CN111972414A - Sterilization disinfectant for medical departments and preparation method thereof - Google Patents

Sterilization disinfectant for medical departments and preparation method thereof Download PDF

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CN111972414A
CN111972414A CN202011001594.XA CN202011001594A CN111972414A CN 111972414 A CN111972414 A CN 111972414A CN 202011001594 A CN202011001594 A CN 202011001594A CN 111972414 A CN111972414 A CN 111972414A
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parts
sterilizing
mixed solution
chlorate
deionized water
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段宁徽
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Anhui Yunqin Technology Co ltd
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Anhui Yunqin Technology Co ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/22—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
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    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
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    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
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    • A01N59/20—Copper
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Abstract

The invention provides a sterilizing disinfectant for medical departments and a preparation method thereof, and relates to the technical field of medical sterilization and disinfection, wherein the sterilizing disinfectant comprises the following raw materials in parts by weight: 10-30 parts of chlorine dioxide, 1-3 parts of stabilizer, 0.01-0.1 part of surfactant, 0.1-0.3 part of sterilization promoter, 10-15 parts of chlorate, 10-15 parts of sodium chloride, 5-10 parts of traditional Chinese medicine extract, 0.1-0.5 part of plant essential oil and 1200 parts of deionized water. The sterilizing disinfectant prepared by the invention has the advantages of good sterilizing effect, pleasant smell, good stability, convenient transportation and the like.

Description

Sterilization disinfectant for medical departments and preparation method thereof
Technical Field
The invention relates to the technical field of medical sterilization and disinfection, in particular to a sterilization disinfectant for medical departments and a preparation method thereof.
Background
Common bacteria for nosocomial infection include escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, candida albicans and the like, and the bacteria show multiple drug resistance along with the application of a large amount of antibiotics. Disinfectants and antibiotics belong to chemical substances with special antimicrobial effects, and the action mechanisms of the disinfectants and the antibiotics on microorganisms are also in many same or similar places. The strain is resistant to the disinfectant. Effectively killing hospital infectious bacteria and controlling hospital infection are important subjects faced by various hospitals at present.
Chlorine dioxide is an effective bactericide in water containing less organic matters, has better permeability on cell walls, has stronger capacity of killing endospores than chlorine, and has good killing effect on heterotrophic bacteria, sulfate reducing bacteria and fungi in a water path system. After being dissolved in water, the chlorine dioxide hardly reacts with the water chemically, does not exist in a dimer or polymer state, and has higher diffusion speed and permeability in the water than chlorine. The molecule of chlorine dioxide is composed of a chlorine atom and two oxygen atoms, the chlorine atom is combined with the two oxygen atoms by two coordinate bonds, and because the electronic structure of the molecule is in an unsaturated state, the oxidation performance of the molecule is shown in that the molecule attacks electron-rich or electron-donating atoms or atomic groups (such as enzyme, sulfide, nitride and the like containing sulfhydryl in amino acid) and forcibly grazes electrons to generate and lose activity or change the property of substances, thereby inhibiting the synthesis of microbial protein and further achieving the aims of sterilization and disinfection.
Chlorine dioxide has the function of killing general bacteria, has good effect of killing spores, viruses, heterotrophic bacteria, iron bacteria, sulfate reducing bacteria, fungi and the like, is not easy to generate drug resistance, and has good and lasting effect on typhoid fever, hepatitis A, hepatitis B, poliomyelitis, AIDS viruses and the like. The removal of the botulinum toxin in the drinking water by the chlorine dioxide is an important index of the hygiene effect, the botulinum toxin can be killed within minutes, the effect is far better than that of liquid chlorine, the low-dose chlorine dioxide also has a strong worm killing effect, the water louse can be killed by using 0.5mg/L of chlorine dioxide, the liquid chlorine needs 6-7mg/L, and the chlorine dioxide can successfully control the musty smell, the fish smell and the peculiar smell brought by actinomycetes.
At present, chlorine dioxide products on the market mainly have two dosage forms, namely a liquid type chlorine dioxide preparation and a solid type chlorine dioxide preparation. Liquid-type stabilized chlorine dioxide is to stabilize chlorine dioxide gas in an inert solution to form a 2% or 5% aqueous solution. The solid chlorine dioxide preparation is generally prepared by putting a chlorine dioxide parent in water to react to generate chlorine dioxide, but chlorine gas is generated during the reaction, so that certain potential safety hazard exists.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a sterilizing disinfectant for medical departments and a preparation method thereof, wherein the sterilizing disinfectant is prepared from chlorine dioxide, a sterilization accelerant, a traditional Chinese medicine extract, plant essential oil and the like, and has the advantages of good sterilizing effect, pleasant smell, good stability, convenience in transportation and the like.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme:
a sterilization disinfectant for medical departments comprises the following raw materials in parts by weight: 10-30 parts of chlorine dioxide, 1-3 parts of stabilizer, 0.01-0.1 part of surfactant, 0.1-0.3 part of sterilization promoter, 10-15 parts of chlorate, 10-15 parts of sodium chloride, 5-10 parts of traditional Chinese medicine extract, 0.1-0.5 part of plant essential oil and 1200 parts of deionized water.
Further, the preparation method of the sterilizing disinfectant comprises the following steps:
(1) weighing raw materials according to a ratio, putting nine tenth of deionized water by weight in the ratio into a low-temperature closed container, cooling the deionized water, keeping the temperature at 0-5 ℃, and dissolving chlorine dioxide into the deionized water to obtain a mixed solution A;
(2) adding a stabilizer, a sterilization promoter, chlorate, sodium chloride and a pH regulator into the mixed solution A, and mixing and stirring to obtain mixed solution B;
(3) mixing the traditional Chinese medicine extract, the plant essential oil, the surfactant and the rest deionized water, and stirring to obtain a mixed solution C;
(4) and adding the mixed solution C into the mixed solution B, and mixing and stirring to obtain the sterilizing disinfectant.
Further, the sterilization accelerant comprises one or more of ferric chloride, zinc sulfate and copper sulfate.
Further, the traditional Chinese medicine extract is a mixture of baicalin, berberine, a radix sophorae flavescentis extract and a honeysuckle extract in a mass ratio of 1:3:8: 1.
Further, the preparation method of the plant essential oil comprises the following steps:
(1) cleaning the plant to be extracted with the essential oil, and drying for later use;
(2) soaking the plant in the step (1) in ethanol, stirring for 1-3 hours at 50-60 ℃, cooling and filtering;
(3) crushing the plant obtained in the step (2) in a high-speed crusher to obtain crushed material;
(4) placing the crushed material obtained in the step (3) into ethanol with mass concentration for microwave extraction for 20-30 minutes, and then cooling and filtering to obtain filtrate;
(5) adding the filtrate obtained in the step (4) into steam distillation equipment, heating and refluxing, collecting distillation fractions, and naturally cooling to obtain distillate;
(6) mixing the distillate obtained in the step (5) with ethyl acetate and water, standing at 10-15 deg.C for layering, collecting organic layer, adding desiccant into the organic layer, stirring, standing, collecting organic layer, concentrating under reduced pressure, and removing ethyl acetate to obtain plant essential oil.
Further, the mass concentration of the ethanol in the step (2) of the preparation method of the plant essential oil is 60-70%, and the mass concentration of the ethanol in the step (4) is 70-80%.
Further, in the method for preparing the plant essential oil, the plant to be extracted in the step (1) is one of bergamot, rose, lavender and eucalyptus leaves.
Further, the chlorate comprises one or more of sodium chlorate, potassium chlorate, barium chlorate and magnesium chlorate.
Further, the surfactant is a fluorine-containing anionic surfactant.
Further, the stabilizer comprises one of diethylene triamine penta methylene phosphonic acid heptasodium salt, diethylene triamine penta methylene phosphonic acid, bis 1, 6-hexamethylene triamine penta methylene phosphonic acid and ethylene diamine tetraacetic acid.
(III) advantageous effects
The invention aims to overcome the problems in the prior art and provides a sterilizing disinfectant for medical departments and a preparation method thereof.
The invention provides a sterilizing disinfectant for medical departments and a preparation method thereof.
Chlorine dioxide has good permeability to cell walls, and the oxidation performance of chlorine dioxide is shown in that the chlorine dioxide attacks atoms or atomic groups rich in electrons or supplying electrons (such as enzyme containing sulfhydryl in amino acid, sulfide, nitride and the like), and the chlorine dioxide forcibly grabs electrons to generate inactive substances or change the properties of the substances, so that the synthesis of microbial protein is inhibited, and the aims of sterilization and disinfection are achieved. Ethylene diamine tetraacetic acid is used as a stabilizer to form a chelate with chlorine dioxide, so that the ethylene diamine tetraacetic acid is stable in a solution in a molecular form and can accept stronger electrons and stronger metal ions to be released through a displacement reaction, and the ethylene diamine tetraacetic acid also has the capabilities of effectively overcoming gram-negative bacteria and increasing the permeability of chlorine dioxide to cell walls. Chlorate and sodium chloride are added to increase the stability of chlorine dioxide in deionized water, thereby facilitating the transportation and storage of the sterilizing disinfectant. The addition of the sterilization accelerant increases the heavy metal components in the sterilization disinfectant, thereby increasing the sterilization and disinfection effects.
The plant sterilization and disinfection components are obtained by compounding baicalin, berberine, the sophora flavescens extracts and the honeysuckle extracts, the antibacterial spectrum of the plant sterilization and disinfection components can be expanded by compounding different antibacterial plant active ingredients, the bacteria are not easy to generate drug resistance, and the plant sterilization and disinfection components are compounded with a small amount of chemical sterilizing substances, so that the high-efficiency and quick-acting performance of the chemical sterilizing substances can be utilized, and the advantages of environmental protection, complexity, broad-spectrum antibacterial property, difficult generation of resistance of the bacteria and the like of natural antibacterial ingredients can be utilized, thereby achieving complementation and having good compounding combined antibacterial effect. The added plant essential oil not only has the auxiliary effect of sterilization, but also can improve the smell of the sterilization disinfectant. The obtained sterilizing and disinfecting liquid has the advantages of good sterilizing and disinfecting effect, pleasant smell, convenient storage and transportation and the like.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a sterilization disinfectant for medical departments comprises the following raw materials in parts by weight: 10 parts of chlorine dioxide, 1 part of ethylene diamine tetraacetic acid, 0.01 part of perfluorononene oxy benzene sulfonic acid sodium, 0.1 part of copper sulfate, 10 parts of sodium chlorate, 10 parts of sodium chloride, 5 parts of traditional Chinese medicine extract, 0.1 part of plant essential oil and 1000 parts of deionized water.
The traditional Chinese medicine extract is a mixture of baicalin, berberine, a radix sophorae flavescentis extract and a honeysuckle extract in a mass ratio of 1:3:8: 1.
The preparation method of the plant essential oil comprises the following steps:
(1) cleaning bergamot, and drying for later use;
(2) soaking the plant in the step (1) in ethanol with the mass concentration of 60%, stirring for 1 hour at 50 ℃, cooling and filtering;
(3) crushing the plant obtained in the step (2) in a high-speed crusher to obtain crushed material;
(4) placing the crushed material obtained in the step (3) into ethanol with the mass concentration of 70% for microwave extraction for 20 minutes, and then cooling and filtering to obtain filtrate;
(5) adding the filtrate obtained in the step (4) into steam distillation equipment, heating and refluxing, collecting distillation fractions, and naturally cooling to obtain distillate;
(6) mixing the distillate obtained in the step (5) with ethyl acetate and water, standing at 10 ℃ for layering, collecting an organic layer, adding a drying agent into the organic layer, stirring, standing, taking the organic layer, concentrating under reduced pressure, and removing ethyl acetate to obtain the plant essential oil.
The preparation method of the sterilizing disinfectant comprises the following steps:
(1) weighing raw materials according to a ratio, adding nine tenth of deionized water by weight in the ratio into a low-temperature closed container, cooling the deionized water and keeping the temperature at 0 ℃, and dissolving chlorine dioxide into the deionized water to obtain a mixed solution A;
(2) adding ethylenediamine tetraacetic acid, copper sulfate, sodium chlorate and sodium chloride into the mixed solution A, and mixing and stirring to obtain mixed solution B;
(3) mixing and stirring the traditional Chinese medicine extract, the plant essential oil, the sodium perfluorononenoxybenzene sulfonate and the rest deionized water to obtain a mixed solution C;
(4) and adding the mixed solution C into the mixed solution B, and mixing and stirring to obtain the sterilizing disinfectant.
Example 2:
a sterilization disinfectant for medical departments comprises the following raw materials in parts by weight: 30 parts of chlorine dioxide, 3 parts of ethylene diamine tetraacetic acid, 0.1 part of perfluorononene oxy benzene sulfonate, 0.3 part of copper sulfate, 15 parts of sodium chlorate, 15 parts of sodium chloride, 10 parts of traditional Chinese medicine extract, 0.5 part of plant essential oil and 1200 parts of deionized water.
The traditional Chinese medicine extract is a mixture of baicalin, berberine, a radix sophorae flavescentis extract and a honeysuckle extract in a mass ratio of 1:3:8: 1.
The preparation method of the plant essential oil is the same as the preparation method of the plant essential oil in example 1.
The preparation method of the sterilizing disinfectant comprises the following steps:
(1) weighing raw materials according to a ratio, adding nine tenth of deionized water by weight in the ratio into a low-temperature closed container, cooling the deionized water, keeping the temperature at 5 ℃, and dissolving chlorine dioxide into the deionized water to obtain a mixed solution A;
(2) adding ethylenediamine tetraacetic acid, copper sulfate, sodium chlorate and sodium chloride into the mixed solution A, and mixing and stirring to obtain mixed solution B;
(3) mixing and stirring the traditional Chinese medicine extract, the plant essential oil, the sodium perfluorononenoxybenzene sulfonate and the rest deionized water to obtain a mixed solution C;
(4) and adding the mixed solution C into the mixed solution B, and mixing and stirring to obtain the sterilizing disinfectant.
Example 3:
a sterilization disinfectant for medical departments comprises the following raw materials in parts by weight: 10 parts of chlorine dioxide, 3 parts of ethylene diamine tetraacetic acid, 0.01 part of perfluorononene oxy benzene sulfonic acid sodium, 0.3 part of copper sulfate, 10 parts of sodium chlorate, 15 parts of sodium chloride, 10 parts of traditional Chinese medicine extract, 0.1 part of plant essential oil and 1200 parts of deionized water.
The traditional Chinese medicine extract is a mixture of baicalin, berberine, a radix sophorae flavescentis extract and a honeysuckle extract in a mass ratio of 1:3:8: 1.
The preparation method of the plant essential oil is the same as the preparation method of the plant essential oil in example 1.
The preparation method of the sterilizing disinfectant comprises the following steps:
(1) weighing raw materials according to a ratio, adding nine tenth of deionized water by weight in the ratio into a low-temperature closed container, cooling the deionized water and keeping the temperature at 0 ℃, and dissolving chlorine dioxide into the deionized water to obtain a mixed solution A;
(2) adding ethylenediamine tetraacetic acid, copper sulfate, sodium chlorate and sodium chloride into the mixed solution A, and mixing and stirring to obtain mixed solution B;
(3) mixing and stirring the traditional Chinese medicine extract, the plant essential oil, the sodium perfluorononenoxybenzene sulfonate and the rest deionized water to obtain a mixed solution C;
(4) and adding the mixed solution C into the mixed solution B, and mixing and stirring to obtain the sterilizing disinfectant.
Example 4:
a sterilization disinfectant for medical departments comprises the following raw materials in parts by weight: 30 parts of chlorine dioxide, 1 part of ethylene diamine tetraacetic acid, 0.1 part of perfluorononene oxy benzene sulfonate, 0.1 part of copper sulfate, 15 parts of sodium chlorate, 10 parts of sodium chloride, 5 parts of traditional Chinese medicine extract, 0.5 part of plant essential oil and 1000 parts of deionized water.
The traditional Chinese medicine extract is a mixture of baicalin, berberine, a radix sophorae flavescentis extract and a honeysuckle extract in a mass ratio of 1:3:8: 1.
The preparation method of the plant essential oil is the same as the preparation method of the plant essential oil in example 1.
The preparation method of the sterilizing disinfectant comprises the following steps:
(1) weighing raw materials according to a ratio, adding nine tenth of deionized water by weight in the ratio into a low-temperature closed container, cooling the deionized water, keeping the temperature at 5 ℃, and dissolving chlorine dioxide into the deionized water to obtain a mixed solution A;
(2) adding ethylenediamine tetraacetic acid, copper sulfate, sodium chlorate and sodium chloride into the mixed solution A, and mixing and stirring to obtain mixed solution B;
(3) mixing and stirring the traditional Chinese medicine extract, the plant essential oil, the sodium perfluorononenoxybenzene sulfonate and the rest deionized water to obtain a mixed solution C;
(4) and adding the mixed solution C into the mixed solution B, and mixing and stirring to obtain the sterilizing disinfectant.
Example 5:
a sterilization disinfectant for medical departments comprises the following raw materials in parts by weight: 25 parts of chlorine dioxide, 1.5 parts of ethylene diamine tetraacetic acid, 0.1 part of perfluorononenoxybenzene sodium sulfonate, 0.2 part of copper sulfate, 15 parts of sodium chlorate, 15 parts of sodium chloride, 8 parts of traditional Chinese medicine extract, 0.5 part of plant essential oil and 1000 parts of deionized water.
The traditional Chinese medicine extract is a mixture of baicalin, berberine, a radix sophorae flavescentis extract and a honeysuckle extract in a mass ratio of 1:3:8: 1.
The preparation method of the plant essential oil is the same as the preparation method of the plant essential oil in example 1.
The preparation method of the sterilizing disinfectant comprises the following steps:
(1) weighing raw materials according to a ratio, adding nine tenth of deionized water by weight in the ratio into a low-temperature closed container, cooling the deionized water and keeping the temperature at 0 ℃, and dissolving chlorine dioxide into the deionized water to obtain a mixed solution A;
(2) adding ethylenediamine tetraacetic acid, copper sulfate, sodium chlorate and sodium chloride into the mixed solution A, and mixing and stirring to obtain mixed solution B;
(3) mixing and stirring the traditional Chinese medicine extract, the plant essential oil, the sodium perfluorononenoxybenzene sulfonate and the rest deionized water to obtain a mixed solution C;
(4) and adding the mixed solution C into the mixed solution B, and mixing and stirring to obtain the sterilizing disinfectant.
The sterilizing and disinfecting solutions were prepared according to the compositions and methods of examples 1 to 5, and tested for chlorine dioxide content, chlorine dioxide chemical yield, product storage stability, and microbial detection under the same conditions.
1. Detecting the content of chlorine dioxide:
(1) adding 100mL of distilled water and a proper amount of phosphate buffer solution into a 500mL iodine measuring flask, sucking 10-50 mL of sterilization disinfectant, adding 10mL of potassium iodide solution, mixing uniformly, and measuring the pH value of the solution by using an acidity detector to keep the pH value at about 7 (adjusting the pH value by using the phosphate buffer solution). After titration to a pale yellow color with 0.01mol/L sodium thiosulfate, 1mL of the starch solution was added and the titration continued until the blue color just disappeared and a reading of A was recorded.
(3) 2.5mL of 2.5mol/L hydrochloric acid solution was added to the above solution from which the A value was dropped, and the mixture was left in the dark for 5 min. Titration with sodium thiosulfate titrant at 0.01mol/L until the blue color disappears and a reading B is recorded.
(4) 100mL of distilled water and a proper amount of phosphate buffer solution are added into a 500mL iodine measuring flask, 50mL of chlorine dioxide solution or diluent is absorbed and added into the iodine measuring flask, and then high-purity nitrogen is introduced to blow till yellow-green color disappears, which is about 20 min. 10mL potassium iodide solution was added, and 1mL starch solution was added when the solution was titrated to light yellow with 0.01mol/L sodium thiosulfate, and the solution was dropped until the blue color just disappeared, and the reading was recorded as C.
(5) 2.5mL of 2.5mol/L hydrochloric acid solution was added to the above solution from which the C value was dropped, and the mixture was left in the dark for 5 min. Titration with 0.01mol/L sodium thiosulfate titrant until the blue color disappears recorded a reading of D. The measurement was repeated 2 times, and the average value of 2 times was calculated as follows.
(6) Computing
ClO2(mg/L)＝(B-D)×c×16863÷V
Cl2(mg/L)＝[A-(B-D)÷4]×c×35450÷V
In the formula: a, B, C and D are the dosage of sodium thiosulfate titration solution in each step, and are mL;
v is the sample volume of the disinfectant, mL;
and c is the concentration of sodium thiosulfate titration solution, mol/L.
2. And (3) detecting the storage stability of the product:
a54 ℃ thermally accelerated stability test was carried out. And (3) storing the packaged product for 14 days under the environmental conditions that the temperature is more than or equal to 54 ℃ and the relative humidity is more than or equal to 75%, and detecting the reduction rate of the chlorine dioxide content according to the method for detecting the chlorine dioxide content.
(3) And (3) detecting microorganisms: the test is carried out according to the sterilization performance test method in appendix C3 of GB 15979-2002 hygienic Standard for Disposable sanitary articles.
The results are shown in Table 1.
Table 1:
Figure BDA0002694520390000091
Figure BDA0002694520390000101
as can be seen from Table 1, the sterilizing and disinfecting liquid prepared by the embodiment of the invention has the advantages of good sterilizing and disinfecting effects, pleasant smell, convenience in storage and transportation and the like, can meet the requirements of the industry, and has a good application prospect.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims (10)

1. The sterilizing disinfectant for the medical department is characterized by comprising the following raw materials in parts by weight: 10-30 parts of chlorine dioxide, 1-3 parts of stabilizer, 0.01-0.1 part of surfactant, 0.1-0.3 part of sterilization promoter, 10-15 parts of chlorate, 10-15 parts of sodium chloride, 5-10 parts of traditional Chinese medicine extract, 0.1-0.5 part of plant essential oil and 1200 parts of deionized water.
2. The sterilizing and disinfecting liquid for medical departments as claimed in claim 1, wherein: the preparation method of the sterilizing disinfectant comprises the following steps:
(1) weighing raw materials according to a ratio, putting nine tenth of deionized water by weight in the ratio into a low-temperature closed container, cooling the deionized water, keeping the temperature at 0-5 ℃, and dissolving chlorine dioxide into the deionized water to obtain a mixed solution A;
(2) adding a stabilizer, a sterilization promoter, chlorate, sodium chloride and a pH regulator into the mixed solution A, and mixing and stirring to obtain mixed solution B;
(3) mixing the traditional Chinese medicine extract, the plant essential oil, the surfactant and the rest deionized water, and stirring to obtain a mixed solution C;
(4) and adding the mixed solution C into the mixed solution B, and mixing and stirring to obtain the sterilizing disinfectant.
3. The sterilizing and disinfecting solution for medical departments as claimed in claim 1 or 2, wherein the sterilizing accelerator comprises one or more of ferric chloride, zinc sulfate and copper sulfate.
4. The sterilizing and disinfecting solution for medical departments according to claim 1 or 2, wherein the traditional Chinese medicine extract is a mixture of baicalin, berberine, radix sophorae flavescentis extract and honeysuckle extract in a mass ratio of 1:3:8: 1.
5. The sterilizing and disinfecting solution for medical departments according to claim 1, wherein the preparation method of the plant essential oil comprises the following steps:
(1) cleaning the plant to be extracted with the essential oil, and drying for later use;
(2) soaking the plant in the step (1) in ethanol, stirring for 1-3 hours at 50-60 ℃, cooling and filtering;
(3) crushing the plant obtained in the step (2) in a high-speed crusher to obtain crushed material;
(4) placing the crushed material obtained in the step (3) into ethanol with mass concentration for microwave extraction for 20-30 minutes, and then cooling and filtering to obtain filtrate;
(5) adding the filtrate obtained in the step (4) into steam distillation equipment, heating and refluxing, collecting distillation fractions, and naturally cooling to obtain distillate;
(6) mixing the distillate obtained in the step (5) with ethyl acetate and water, standing at 10-15 deg.C for layering, collecting organic layer, adding desiccant into the organic layer, stirring, standing, collecting organic layer, concentrating under reduced pressure, and removing ethyl acetate to obtain plant essential oil.
6. The sterilizing and disinfecting solution for medical departments according to claim 5, wherein the ethanol mass concentration in the step (2) is 60-70%, and the ethanol mass concentration in the step (4) is 70-80%.
7. The sterilizing and disinfecting solution for medical departments according to claim 5, wherein the plant to be extracted in step (1) is one of bergamot, rose, lavender and eucalyptus leaves.
8. The disinfectant liquid for medical departments as claimed in claim 1 or 2, wherein said chlorate comprises one or more of sodium chlorate, potassium chlorate, barium chlorate and magnesium chlorate.
9. The disinfectant liquid for medical departments as claimed in claim 1 or 2, wherein said surfactant is a fluorine-containing anionic surfactant.
10. The sterilizing and disinfecting solution for medical departments according to claim 1 or 2, which is characterized in that: the stabilizer comprises one of diethylene triamine pentamethylene phosphonic acid heptasodium salt, diethylene triamine pentamethylene phosphonic acid, bis (1, 6-hexamethylene triamine pentamethylene phosphonic acid) and ethylene diamine tetraacetic acid.
CN202011001594.XA 2020-09-22 2020-09-22 Sterilization disinfectant for medical departments and preparation method thereof Withdrawn CN111972414A (en)

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