CN111920854A - Traditional Chinese medicine acupoint application plaster for treating simple myopia and preparation method thereof - Google Patents
Traditional Chinese medicine acupoint application plaster for treating simple myopia and preparation method thereof Download PDFInfo
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Abstract
The invention provides a Chinese medicinal acupoint application plaster for treating simple myopia and a preparation method thereof, wherein Chinese angelica, white paeony root, corydalis amabilis, rhizoma corydalis, menthol and purified water are used as medicaments to be decocted in water, and are naturally cooled to normal temperature; then soaking the disinfected clean gauze in the water decoction prepared in the step one, and adding borneol; the soaking time is not less than 30 minutes; then the soaked gauze is folded into a block shape and is filled into a dressing bag to prepare a dressing agent plaster; the patch comprises an outer patch coating and an inner patch coating, wherein one side of the edge of the inner patch coating and the outer patch coating is bonded into a bag-shaped structure with an opening, the inner patch coating is provided with a penetration hole, the outer side of the inner patch coating is also provided with a protective film, and the peripheral edge of the outer patch coating is provided with a patch adhesive layer. The invention can be used for the blood-nourishing and tendon-softening pasting agent therapy to enable the medicine to directly act on eyes, has simple and convenient operation, little pain, high patient acceptance and high feasibility in myopia prevention and control, and has obvious advantages compared with the oral administration of traditional Chinese medicines.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine pharmacy, in particular to a traditional Chinese medicine acupoint application plaster for treating simple myopia and a preparation method thereof.
Background
Many researches show that the traditional Chinese medicine has unique advantages in the aspect of myopia prevention and control, the traditional Chinese medicine is applied to prevent and control myopia at home at present, the myopia is generally considered to be mainly related to deficiency of heart yang, deficiency of both liver and kidney and deficiency of qi and blood, and satisfactory effects can be achieved through dialectical treatment.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a traditional Chinese medicine acupoint application plaster for treating simple myopia and a preparation method thereof.
In order to achieve the purpose, the technical scheme adopted by the invention for solving the technical problem is as follows: a method for preparing a Chinese medicinal acupoint patch for treating simple myopia comprises the following steps:
the first step is as follows: decocting radix Angelicae sinensis, radix Paeoniae alba, rhizoma corydalis Decumbentis, rhizoma corydalis, Mentholum, and purified water, and naturally cooling to room temperature;
the second step is that: soaking the disinfected clean gauze in the decoction prepared in the step one, and adding borneol; the soaking time is not less than 30 minutes;
the third step: folding the soaked gauze into blocks, and filling the blocks into a patch bag to prepare a patch;
in the above steps, the ratio of the Chinese angelica, the white paeony root, the corydalis amabilis, the rhizoma corydalis, the borneol, the menthol and the purified water is 5: 1: 50;
the invention further provides a preparation method of the traditional Chinese medicine acupoint application for treating simple myopia, which comprises the steps of soaking the traditional Chinese medicines in purified water for not less than 6 hours at normal temperature, heating to 60-70 ℃, preserving heat for 30 minutes, heating to 100 ℃, preserving heat for 5-10 minutes, and naturally cooling when the decoction is decocted in the first step.
The invention further provides a patch, which comprises an outer patch coating and an inner patch coating, wherein one side of the edge of the inner patch coating and the outer patch coating are bonded into a bag-shaped structure with an opening, the inner patch coating is provided with a penetration hole, and the outer side of the inner patch coating is also provided with a protective film.
The invention further provides the patch, wherein the peripheral edge of the outer patch layer is provided with a patch adhesive layer, the outer side of the patch adhesive layer is also provided with a protective layer, the inner patch layer is a cotton cloth layer, and the outer patch layer is a non-woven cloth layer.
The invention has the beneficial effects that: the invention can be used for the blood-nourishing and tendon-softening pasting agent therapy to enable the medicine to directly act on eyes, has simple and convenient operation, little pain, high patient acceptance and high feasibility in myopia prevention and control, and has obvious advantages compared with the oral administration of traditional Chinese medicines.
Drawings
FIG. 1 is a schematic view of the structure of the patch of the present invention;
in the figure: 1. coating the outer layer; 2. coating the inner side; 3. a protective film; 4. pasting a glue layer; 5. and (4) a protective layer.
Detailed Description
Example 1
The invention discloses a method for preparing a traditional Chinese medicine acupoint application paste for treating simple myopia, which comprises the following preferred steps:
the first step is as follows: 50 g of angelica, 50 g of white peony root, 50 g of corydalis amabilis, 50 g of rhizoma corydalis, 10 g of menthol and 500 g of purified water are taken as raw materials to be decocted into a decoction, and the decoction is naturally cooled to the normal temperature;
the second step is that: soaking the disinfected clean gauze in the decoction prepared in the step one, and adding 10 g of borneol; the soaking time is 30 minutes;
the third step: folding the soaked gauze into blocks, and filling the blocks into a patch bag to prepare a patch;
furthermore, when the decoction is decocted in the first step, the Chinese herbal medicines are soaked in purified water for 6 hours at normal temperature, then heated to 60 +/-5 ℃ and kept warm for 30 minutes, then heated to 100 ℃ and kept warm for 10 minutes and then naturally cooled.
The invention provides an adhesive plaster, which comprises an outer adhesive coating layer 1 and an inner adhesive coating layer 2, wherein one side of the edge of the inner adhesive coating layer 2 and the outer adhesive coating layer 1 is adhered to form a bag-shaped structure with an opening, the inner adhesive coating layer 2 is provided with a penetration hole, and the outer side of the inner adhesive coating layer 2 is also provided with a protective film 3.
Furthermore, the peripheral edge of the outer coating layer 1 is provided with a bonding adhesive layer 4, the outer side of the bonding adhesive layer 4 is also provided with a protective layer 5, the inner coating layer 2 is a cotton fabric layer, and the outer coating layer 1 is a non-woven fabric layer.
Example 2
The invention discloses a method for preparing a traditional Chinese medicine acupoint application paste for treating simple myopia, which comprises the following preferred steps:
the first step is as follows: 50 g of angelica, 50 g of white peony root, 50 g of corydalis amabilis, 50 g of rhizoma corydalis, 10 g of menthol and 500 g of purified water are taken as raw materials to be decocted into a decoction, and the decoction is naturally cooled to the normal temperature;
the second step is that: soaking the disinfected clean gauze in the decoction prepared in the step one, and adding 10 g of borneol; the soaking time is 30 minutes;
the third step: folding the soaked gauze into blocks, and filling the blocks into a patch bag to prepare a patch;
furthermore, when the decoction is decocted in the first step, the Chinese herbal medicines are firstly soaked in purified water for 8 hours at normal temperature, then heated to 65 +/-5 ℃ and kept warm for 30 minutes, then heated to 100 ℃ and kept warm for 5 minutes and then naturally cooled.
The invention provides an adhesive plaster, which comprises an outer adhesive coating layer 1 and an inner adhesive coating layer 2, wherein one side of the edge of the inner adhesive coating layer 2 and the outer adhesive coating layer 1 is adhered to form a bag-shaped structure with an opening, the inner adhesive coating layer 2 is provided with a penetration hole, and the outer side of the inner adhesive coating layer 2 is also provided with a protective film 3.
Furthermore, the peripheral edge of the outer coating layer 1 is provided with a bonding adhesive layer 4, the outer side of the bonding adhesive layer 4 is also provided with a protective layer 5, the inner coating layer 2 is a cotton fabric layer, and the outer coating layer 1 is a non-woven fabric layer.
The normal temperature in the embodiment is 20-25 ℃, western medicine myopia prevention and control has certain limitation, the traditional Chinese medicine therapy gradually becomes the development trend of myopia prevention and control in the medical field, but the defects of slow effect taking, poor compliance, inconvenient operation and the like still exist. Based on the severe situation, a simple and effective myopia prevention and treatment method is found. The blood-nourishing and tendon-softening plaster is a traditional Chinese medicine external treatment method which is characterized in that traditional Chinese medicines with the effects of promoting blood circulation and nourishing blood, removing nebula and improving eyesight are decocted into a water decoction, and the gauze is soaked in the liquid medicine for external application after the water decoction is cooled. The early clinical researches prove that the technology can effectively delay the myopia progress, reduce the high myopia morbidity and improve the life quality of patients.
At present, global myopia and high myopia patients increase year by year, and are estimated to exceed 47 hundred million and nearly 10 hundred million people respectively by 2050, and China is the first big myopia country. The myopia prevention and control of children and teenagers is a key for solving the problem and is a hotspot and difficulty of current research. The clinical research in the early period of the team proves that the eye acupoint application of the compatibility of six traditional Chinese medicines of Chinese angelica, white paeony root, corydalis amabilis, rhizoma corydalis, borneol and menthol has significant significance for improving the adjustment sensitivity of children with myopia and effectively delaying the myopia progress. The traditional Chinese medicine is currently applied to research special items in thirteen-five key fields of Chinese academy of science, and is used for researching diagnosis and treatment modes of myopia development intervention (ZZ10-017) and 2017.2-2020.12.
The application agent of the invention attaches importance to the comprehensive curative effects of enriching blood, nourishing liver, promoting blood circulation, softening tendons and permeating eyes, the angelica in the prescription used in the research has obvious effects of enriching blood and promoting blood circulation, the effects of enriching blood and replenishing essence are achieved to benefit liver and kidney, the effects of promoting blood circulation and dredging collaterals are achieved to promote spleen transportation, and the effects of nourishing qi and blood and achieving the effect of the Shengao can be reached. White peony root, radix Paeoniae alba is bitter in taste and slightly cold in nature, enters liver and spleen channels, has the effects of tonifying liver blood, nourishing blood, softening liver and improving eyesight, and is especially suitable for patients with liver deficiency. Dang Gui excels in tonifying blood and activating blood, and Bai Shao excels in nourishing blood and astringing yin, so they both have the actions of nourishing liver, tonifying blood, nourishing yin and improving eyesight. Rhizoma corydalis Decumbentis has effects of promoting blood circulation, dredging collaterals, activating qi-flowing and relieving pain. Modern pharmacological research finds that the main component of corydalis amabilis, namely protopine, can directly relax smooth muscles and relieve the tension of ciliary muscles. Rhizoma corydalis, which belongs to the liver, can accelerate the blood circulation and metabolism of eyes, can remarkably increase the blood flow of eyeground of mice and the content of trace elements such as Cu, Zn, Mn and the like in the vitreous body of an eyeball, and is an indispensable essential element for the growth and development of the eyeball and the visual function. Borneol and menthol are common aromatic resuscitation inducing Chinese medicines and have high use frequency in ophthalmology. Research shows that the borneol has the functions of opening biological barriers and promoting drug permeation and has mild analgesic and anti-inflammatory effects; the pharmacological action of the menthol is similar to that of the borneol, the external pharmacological action is beneficial to promoting the percutaneous absorption of the medicine, has very good anti-inflammatory and antibacterial effects, and can clear head and eyes, promote qi circulation and relieve depression. The application of the invention integrates the advantages of traditional Chinese medicine, acupuncture point and application. The traditional Chinese medicine is directly applied to the affected part, and directly acts on acupuncture points around the eyes, so that blood vessels around the eyes are expanded, blood circulation is accelerated, and the absorption rate of eye tissues to the medicine is promoted.
Clinical trial data:
traditional Chinese medicine integrated therapy intervenes in stratified random control research of teenager simple myopia patients [ J ]. China journal, 2020, 61 (14): 1253-1258
② Tengyue, Zelixia, research on the diagnosis and treatment mode of the intervention and development of myopia by traditional Chinese medicine [ D ]. Beijing: chinese academy of science of traditional chinese medicine, 2019: 1-96
The method comprises the following steps: the method adopts a layering random grouping method, the screening is carried out according to the inclusion and exclusion standards of cases, the diopters of the two eyes of the patients are not completely the same due to the particularity of ophthalmic diseases, so the patients to be treated are divided into two layers of minus 1.00DS and minus 1.00DS to minus 3.00DS by taking one eye with higher myopia degree as the standard, each layer comprises 120 cases, the two layers are respectively divided into a treatment group and a control group at random, and each layer of each group of the treatment group and the control group of the traditional Chinese medicine comprehensive treatment is respectively included into 60 cases according to the early retrospective clinical research result. 156 patients (312 eyes) in 6-12 years old adolescent patients are included at present, and 78 patients (141 eyes) in a treatment group and 78 patients (146 eyes) in a control group meeting the layering requirement are included in statistics. The health promotion of the treatment group, conventional prescription, ear acupoint pressing bean, plum blossom needle tapping, pulse, and traditional Chinese medicine external application, 2 times per week for 3 months; performing health promotion and conventional lens preparation on a control group; the two groups were evaluated for efficacy after 3 months.
As a result: (1) according to the disease curative effect judgment standard, the refractive power stability rate of the treatment group is 36.88 percent, and the stability rate of the control group is 21.23 percent; the progression rate of the treatment group is 63.12 percent, the progression rate of the control group is 78.77 percent, the difference between the stability rate and the progression rate of the two groups has statistical significance (P is less than 0.05), and the refractive index of the treatment group is more stable;
(2) treatment group naked eye vision, diopter, corneal curvature, eye axis self front and back contrast: the treatment groups had decreased naked eye vision, increased diopter, increased axial length after intervention, and the differences were statistically significant (P < 0.05) compared to those before intervention;
(3) the treatment group and the control group are compared after naked eye vision, diopter, corneal curvature and ocular axis intervention: after intervention, the naked eye vision of the treatment group is higher than that of the control group, the diopter of the treatment group is lower than that of the control group, and the difference has statistical significance (P is less than 0.05);
(4) treatment adjustment parameters self-ante-post control: the adjustment sensitivity of a treatment group with less than-1.00 DS and a treatment group with-1.00 DS to-3.00 DS is improved after the intervention, and the difference has statistical significance (P is less than 0.05) compared with that before the intervention;
and (4) conclusion: the traditional Chinese medicine comprehensive therapy intervention can improve the regulation function and control the myopia progression speed to a certain extent, has positive effects on juvenile myopia prevention and control, and is worthy of clinical popularization and application.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (3)
1. A method for preparing a traditional Chinese medicine acupoint application plaster for treating simple myopia is characterized by comprising the following steps:
the first step is as follows: decocting radix Angelicae sinensis, radix Paeoniae alba, rhizoma corydalis Decumbentis, rhizoma corydalis, Mentholum, and purified water, and naturally cooling to room temperature;
the second step is that: soaking the disinfected clean gauze in the decoction prepared in the step one, and adding borneol; the soaking time is not less than 30 minutes;
the third step: folding the soaked gauze into blocks, and filling the blocks into a patch bag to prepare a patch;
in the above steps, the ratio of the Chinese angelica, the white paeony root, the corydalis amabilis, the rhizoma corydalis, the borneol, the menthol and the purified water is 5: 1: 50;
the method for preparing the traditional Chinese medicine acupoint application for treating simple myopia according to claim 1, which is characterized in that: when the decoction is decocted in the first step, the Chinese herbal medicines are soaked in the purified water for not less than 6 hours at normal temperature, then heated to 60-70 ℃ and kept warm for 30 minutes, then heated to 100 ℃ and kept warm for 5-10 minutes and then naturally cooled.
2. The patch according to claim 1 or 2, characterized in that the patch comprises an outer patch coating (1) and an inner patch coating (2), wherein a bag-shaped structure with an opening at one side is adhered between the edge of the inner patch coating (2) and the outer patch coating (1), the inner patch coating (2) is provided with a penetration hole, and a protective film (3) is arranged at the outer side of the inner patch coating (2).
3. The applicator pad according to claim 1, wherein the peripheral edge of the outer pad layer (1) is provided with a layer of adhesive (4), the outer side of the layer of adhesive (4) is further provided with a protective layer (5), the inner pad layer (2) is a cotton cloth layer, and the outer pad layer (1) is a non-woven cloth layer.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112263389A (en) * | 2020-11-17 | 2021-01-26 | 中山大学中山眼科中心 | Ophthalmic medicine moxibustion plaster |
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2020
- 2020-09-16 CN CN202010978297.4A patent/CN111920854A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 滕月等: "中医综合疗法干预青少年单纯性近视患者分层随机对照研究", 《中医杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112263389A (en) * | 2020-11-17 | 2021-01-26 | 中山大学中山眼科中心 | Ophthalmic medicine moxibustion plaster |
| CN112263389B (en) * | 2020-11-17 | 2024-05-14 | 中山大学中山眼科中心 | Ophthalmic medicinal moxibustion plaster |
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