CN111904979A - Traditional Chinese medicine powder for promoting wound healing and preparation method thereof - Google Patents
Traditional Chinese medicine powder for promoting wound healing and preparation method thereof Download PDFInfo
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- CN111904979A CN111904979A CN202010802697.XA CN202010802697A CN111904979A CN 111904979 A CN111904979 A CN 111904979A CN 202010802697 A CN202010802697 A CN 202010802697A CN 111904979 A CN111904979 A CN 111904979A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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Abstract
The embodiment of the invention discloses traditional Chinese medicine powder for promoting wound healing and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. A traditional Chinese medicine powder for promoting wound healing is prepared from the following components in parts by weight: 0.8-1.2 parts of mercuric oxide, 0.8-1.2 parts of borneol and 16-20 parts of calamine. The traditional Chinese medicine powder for promoting wound healing is prepared from red mercuric oxide, borneol and calamine according to a certain proportion, wherein the red mercuric oxide is used for removing toxicity and decay and promoting the generation of new meat of a wound; borneol has the effects of clearing heat, removing purulence and diminishing inflammation; the calamine toxin-drawing, necrosis-removing and granulation-promoting medicine has a good effect of promoting healing of wounds of intractable trauma and diabetic complications, and has the advantage of convenience in use.
Description
Technical Field
The embodiment of the invention relates to the technical field of traditional Chinese medicines, and particularly relates to traditional Chinese medicine powder for promoting wound healing and a preparation method thereof.
Background
The skin is a protective barrier for our body and is also very fragile and often leaves wounds in life for a variety of reasons. If the wound is small, the wound can be healed quickly if treated properly, but if the wound is deep and large, the treatment is not timely or the treatment method is improper, the wound can bleed, infect and suppuration, and the wound can not heal late.
In general, normal wound healing proceeds from a fresh wound, healing wound, to scarring in three stages: contraction and inflammatory reaction stages, granulation tissue repair, and tissue reconstruction to form scars. Among them, the contraction and inflammatory reaction stages are very important, the contraction can avoid excessive bleeding after injury, and the inflammatory reaction mainly plays a role in protecting the body and preventing serious complications such as sepsis.
Reasons for the long-term inability of wounds to heal include: poor blood supply to the wound site; vascular damage at the wound site is severe; after trauma of people with constitutions such as damp heat and the like, a lot of inflammatory mediators exist at the part of a wound, and inflammatory edema is generated in new small blood vessels, so that the healing of the wound is also greatly influenced.
At present, the clinical treatment of wounds comprises conventional debridement and suture and antibacterial treatment, and has the defects of difficult and unhealthy healing of the wounds.
Disclosure of Invention
Therefore, the embodiment of the invention provides traditional Chinese medicine powder for promoting wound healing and a preparation method thereof, and aims to solve the problems of difficult and long-term healing of the existing wound.
In order to achieve the above object, the embodiments of the present invention provide the following technical solutions:
according to a first aspect of the embodiments of the present invention, the embodiments of the present invention provide a traditional Chinese medicine powder for promoting wound healing, which is prepared from the following components in parts by weight: 0.8-1.2 parts of mercuric oxide, 0.8-1.2 parts of borneol and 16-20 parts of calamine.
Further, the feed additive is prepared from the following components in parts by weight: 1 part of mercuric oxide, 1 part of borneol and 18 parts of calamine.
Red lead: removing putrefaction, and can be used for treating intractable wound. Modern pharmacological research proves that the red lead has an inhibiting effect on pseudomonas aeruginosa, escherichia coli, staphylococcus aureus and the like. The red mercuric oxide used in the application is powder purchased from the market of traditional Chinese medicinal materials.
Borneol: has antibacterial effect, and can inhibit the irritation of inflammatory factor to the surface of sore, relieve inflammatory edema of local microcirculation blood vessel, repair the surface of sore, and promote the healing of sore.
Calamine: has antibacterial effect, can kill local staphylococcus, and has no irritation; has astringent, antiseptic, and protective effects on sore surface. So as to restore the microcirculation small blood vessels of the edema on the sore surface to normal, thereby accelerating the healing of the sore opening.
According to a second aspect of the embodiments of the present invention, the embodiments of the present invention provide a preparation method of the above traditional Chinese medicine powder for promoting wound healing, including the following steps:
1) grinding Borneolum Syntheticum and Galamina into fine powder;
2) mixing Red mercuric oxide, Borneolum Syntheticum and Galamina at a certain weight ratio, stirring, sealing and bottling.
Further, the particle size of the fine powder is 200-400 meshes.
According to a third aspect of embodiments of the present invention, there is provided a use of a Chinese medicinal powder as described above in the preparation of a medicament for promoting wound healing.
Further, the wounds include intractable traumatic wounds and diabetic complication wounds.
The traumatic wound refers to a broken part of the body formed by striking, colliding or erosion of chemical substances of an external object, and generally refers to the skin, muscle, mucous membrane, etc. of a human or other animals. The traumatic wound in the present invention does not include a burn.
The diabetes patients have reduced capability of carrying oxygen and nutrient substances because of high blood sugar content, and the wounds are not easy to heal. In addition, microorganisms are easily grown on damaged parts due to high blood sugar, and infection is induced.
The use method of the traditional Chinese medicine powder comprises the following steps: after the wound surface is disinfected and debrided, the medicinal powder is uniformly spread on the wound surface, the wound is bound with sterile gauze or cotton cloth, the dressing cloth is opened the next day, the medicinal powder is spread on the moist wound surface again, the wound surface is covered with a new piece of sterile gauze or cotton cloth without debridement, and the moist wound surface is found every other day.
The application range is as follows: the traditional Chinese medicine powder is particularly suitable for long-term unhealed wound sores and wounds which are difficult to heal and are caused by diabetes. The small collided wound in daily life is simpler to use, the wound is disinfected by iodophor or alcohol, the medicinal powder is scattered after the wound surface is washed by a little physiological saline, and the wound surface is wrapped by the band-aid, so that the side effect of wound infection caused by overlong use time of the band-aid can be effectively prevented.
The traditional Chinese medicine powder is an external preparation, is mainly used for patients who have no improvement on the basic conditions of the sore opening or have unhealed sore opening after trauma, regular treatment and medication treatment for 2 months, and can also be used for common small skin wounds. Contraindications are as follows: the use of wound with suture is contraindicated (since the medicinal powder promotes scab formation at the wound opening, so that the suture and scab can be adhered together, and the wound can be used normally after the suture is removed).
The embodiment of the invention has the following advantages:
the traditional Chinese medicine powder for promoting wound healing is prepared from red mercuric oxide, borneol and calamine according to a certain proportion, wherein the red mercuric oxide is used for removing toxicity and decay and promoting the generation of new meat of a wound; borneol has the effects of clearing heat, removing purulence and diminishing inflammation; the calamine toxin-drawing, necrotic tissue removing and granulation promoting medicine has a good effect of promoting healing of wounds caused by trauma and diabetic complications, and has the advantage of convenience in use.
Detailed Description
The present invention is described in terms of particular embodiments, other advantages and features of the invention will become apparent to those skilled in the art from the following disclosure, and it is to be understood that the described embodiments are merely exemplary of the invention and that it is not intended to limit the invention to the particular embodiments disclosed. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The preparation method of the traditional Chinese medicine powder for promoting wound healing comprises the following steps:
1) respectively grinding borneol and calamine into fine powder with the particle size of 200 meshes for later use;
2) weighing 0.8 part of red mercuric oxide, 1 part of borneol and 20 parts of calamine, mixing, uniformly stirring, sealing and bottling.
Example 2
The preparation method of the traditional Chinese medicine powder for promoting wound healing comprises the following steps:
1) respectively grinding borneol and calamine into fine powder with the particle size of 200-400 meshes for later use;
2) weighing 1 part of red mercuric oxide, 1 part of borneol and 18 parts of calamine, mixing, uniformly stirring, sealing and bottling.
Example 3
The preparation method of the traditional Chinese medicine powder for promoting wound healing comprises the following steps:
1) respectively grinding borneol and calamine into fine powder with the particle size of 400 meshes for later use;
2) weighing 1.2 parts of red mercuric oxide, 1 part of borneol and 16 parts of calamine, mixing, uniformly stirring, sealing and bottling.
Example 4
The preparation method of the traditional Chinese medicine powder for promoting wound healing comprises the following steps:
1) respectively grinding borneol and calamine into fine powder with the particle size of 300 meshes for later use;
2) weighing 1 part of red mercuric oxide, 0.8 part of borneol and 16 parts of calamine, mixing, uniformly stirring, sealing and bottling.
Example 5
The preparation method of the traditional Chinese medicine powder for promoting wound healing comprises the following steps:
1) respectively grinding borneol and calamine into fine powder with the particle size of 200 meshes for later use;
2) weighing 1 part of red mercuric oxide, 1.2 parts of borneol and 20 parts of calamine, mixing, uniformly stirring, sealing and bottling.
Typical cases are as follows:
the skin of the heel bone of the right lower limb is scratched and cracked due to the motor rollover in 2008, the patient can not heal after being hospitalized for 7 days in the urban public hospital except for the unhealed wound of the right heel and thigh without other discomfort, the patient can not heal after being hospitalized for more than 40 days, the patient can take a doctor before listening to the medicine of the application and has a special effect on the unhealed wound, the wound surface is cleaned through a clinic, medicinal powder is spread on the wound surface after the medicine is spread, the wound surface is covered with a thin gauze dressing, the patient is asked to go on the next day if the medicinal powder is spread on the place where the wound surface is wet, the patient does not need to move the place without the wet, the patient is returned after 15 days, the wound surface is healed, and the crust skin is peeled off.
Although the invention has been described in detail above with reference to a general description and specific examples, it will be apparent to one skilled in the art that modifications or improvements may be made thereto based on the invention. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.
Claims (6)
1. The traditional Chinese medicine powder for promoting wound healing is characterized by being prepared from the following components in parts by weight: 0.8-1.2 parts of mercuric oxide, 0.8-1.2 parts of borneol and 16-20 parts of calamine.
2. The traditional Chinese medicine powder for promoting wound healing according to claim 1, which is prepared from the following components in parts by weight: 1 part of mercuric oxide, 1 part of borneol and 18 parts of calamine.
3. A preparation method of the traditional Chinese medicine powder of claim 1, which is characterized by comprising the following steps:
1) grinding Borneolum Syntheticum and Galamina into fine powder;
2) mixing Red mercuric oxide, Borneolum Syntheticum and Galamina at a certain weight ratio, stirring, sealing and bottling.
4. The method as claimed in claim 3, wherein the fine powder has a particle size of 200-400 mesh.
5. Use of a Chinese medicinal powder according to claim 1 for the preparation of a medicament for promoting wound healing.
6. The use of claim 5, wherein the wound comprises a permanent trauma wound and a diabetic complication wound.
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CN202010802697.XA CN111904979A (en) | 2020-08-11 | 2020-08-11 | Traditional Chinese medicine powder for promoting wound healing and preparation method thereof |
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CN202010802697.XA CN111904979A (en) | 2020-08-11 | 2020-08-11 | Traditional Chinese medicine powder for promoting wound healing and preparation method thereof |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1857318A (en) * | 2006-04-14 | 2006-11-08 | 刘皇琼 | Compound Chinese medicine prepn for fast healing trauma and its preparing method |
CN100998604A (en) * | 2007-01-08 | 2007-07-18 | 杜伟 | Traditional Chinese medicine for treat burns and scald and its preparing method |
-
2020
- 2020-08-11 CN CN202010802697.XA patent/CN111904979A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1857318A (en) * | 2006-04-14 | 2006-11-08 | 刘皇琼 | Compound Chinese medicine prepn for fast healing trauma and its preparing method |
CN100998604A (en) * | 2007-01-08 | 2007-07-18 | 杜伟 | Traditional Chinese medicine for treat burns and scald and its preparing method |
Non-Patent Citations (6)
Title |
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庄廷芳,林定周: "炉甘石散对烧伤残余创面的疗效观察", 《辽宁中医杂志》 * |
彭怀仁: "《中医方剂大辞典 第四册》", 28 February 1995, 人民卫生出版社 * |
李今庸: "《李今庸临床医论医话》", 31 July 2017, 中国中医药出版社 * |
李瑞: "冰矾炉甘散外用治疗糖尿病足部溃疡56例", 《中医外治杂志》 * |
谢礼献: ""炉冰散"的临床运用", 《四川中医》 * |
陈加龙: "祛腐生肌散治疗伤口久溃不敛173例", 《陕西中医》 * |
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