CN111888407A - Chinese medicinal preparation for treating gynecological inflammation and its preparation method - Google Patents

Chinese medicinal preparation for treating gynecological inflammation and its preparation method Download PDF

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Publication number
CN111888407A
CN111888407A CN201910377849.3A CN201910377849A CN111888407A CN 111888407 A CN111888407 A CN 111888407A CN 201910377849 A CN201910377849 A CN 201910377849A CN 111888407 A CN111888407 A CN 111888407A
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traditional chinese
chinese medicine
gynecological inflammation
medicine preparation
oxygen
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葛龙海
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Hebei Huanxing Health Food Co ltd
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Hebei Huanxing Health Food Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Reproductive Health (AREA)
  • Biotechnology (AREA)
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  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
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Abstract

The invention relates to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine preparation widely used for gynecological inflammation and a preparation method thereof, wherein the traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 30-50g and matrine 50-70g, and the total amount of oxygen is 20-24g per 1L of oleum Olivarum at 20-26 deg.C and 0.5-1.5 bar. The traditional Chinese medicine composition is simple to prepare, is used for people suffering from urinary tract infection and the like caused by vaginitis, adnexitis, mycoplasma, pelvic inflammation, chlamydia, cervical erosion, ovarian cyst, cervical polyp, uterine fibroid, endometritis, endometriosis, endometrial hyperplasia, functional uterine bleeding and the like, and is simple, convenient and rapid to cure. No toxic side effect, strong penetrating power and no drug resistance.

Description

Chinese medicinal preparation for treating gynecological inflammation and its preparation method
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation widely used for gynecological inflammation and a preparation method thereof.
Background
The gynecological inflammation specifically comprises vaginitis, cervicitis, cervical erosion, adnexitis, ovarian cyst, endometritis, urinary tract infection and the like, symptoms mainly focus on irregular menstruation, leukorrhagia, peculiar smell, change of characters, pruritus of vulva, bleeding, pain, lower abdominal tenderness and the like, and the inflammation is mainly caused by breaking the original ecological environment and imbalance of flora. The existing medicines generally have the problems of slow drug effect and relatively long treatment period, so that the majority of patients suffer from pains, and the physical and mental health of women is influenced
In view of the above, the present invention is particularly proposed.
Disclosure of Invention
Technical problem to be solved
According to the deficiency of the treatment effect of the existing medicines, the invention provides a traditional Chinese medicine preparation widely used for gynecological inflammation and a preparation method thereof, the traditional Chinese medicine preparation widely used for gynecological inflammation improves the treatment and prevention effects of the traditional Chinese medicine by research in the direction of pure traditional Chinese medicines, and clinical verification proves that the traditional Chinese medicine preparation has no toxic or side effect, the effective rate reaches more than 90%, the treatment period is short, the effect is fast, and the effects of treating both symptoms and root causes and improving symptoms can be achieved.
(II) technical scheme
In order to solve the technical problems, the invention provides a traditional Chinese medicine preparation widely used for gynecological inflammation and a preparation method thereof, the preparation method has simple operation steps, saves the operation cost, and is beneficial to further expanding the application in the follow-up process, and the following technical scheme is that:
a traditional Chinese medicine preparation widely used for gynecological inflammation comprises the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 30-50g and matrine 50-70g, and the total amount of oxygen is 20-24g per 1L of oleum Olivarum at 20-26 deg.C and 0.5-1.5 bar.
Preferably, the feed comprises the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 40g and matrine 60g, and oxygen is introduced into 1L of oleum Olivarum at 20-26 deg.C and 1bar to total amount of 22 g.
Preferably, the feed comprises the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 30g and matrine 50g, and oxygen is introduced into 1L of oleum Olivarum at 20-26 deg.C and 0.5bar to total amount of 20 g.
Preferably, the feed comprises the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 50g and matrine 70g, and oxygen is introduced into 1L of oleum Olivarum at 20-26 deg.C and 1.5bar to total amount of 24 g.
Preferentially, the flow rate is controlled to be 4g/h in the oxygen introducing process; the time of oxygen introduction is controlled to be 5-6 hours.
A preparation method of a traditional Chinese medicine preparation widely used for gynecological inflammation comprises the following steps:
1) cleaning 30-50g of phellodendron and 50-70g of matrine, drying, and then crushing to prepare a mixture;
2) mixing the mixture with 75-95% ethanol according to the mass ratio of 1:10-12 to obtain an extraction solution;
3) mixing the extractive solution with 1L oleum Olivarum, stirring, placing into a mixer, introducing medical oxygen into the mixer at 20-26 deg.C and 0.5-1.5bar, controlling flow at 4g/h and oxygen introduction time at 5-6 h. The Chinese medicine preparation widely used for gynecological inflammation is prepared.
(III) advantageous effects
Compared with the prior art, the invention has the beneficial effects that:
the traditional Chinese medicine preparation widely used for gynecological inflammation improves the treatment and prevention effects of the traditional Chinese medicine through research in the direction of pure traditional Chinese medicines, has no toxic or side effect through clinical verification, has the effective rate of more than 90 percent, can achieve the effects of treating both symptoms and root causes and improving symptoms, can obviously improve light symptoms generally within three days after use, and can obviously improve symptoms of heavier symptoms generally within more than half a month.
The invention also provides a preparation method of the traditional Chinese medicine preparation widely used for gynecological inflammation, the preparation method has simple operation steps, strict national sanitary standard requirements are strictly executed during operation, the front and back connection of the operation steps is tight, the operation conditions are mild, the operation time is greatly shortened, the operation cost is saved, and the subsequent further expansion application is facilitated.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
Example 1:
a traditional Chinese medicine preparation widely used for gynecological inflammation comprises the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 40g and matrine 60g, and oxygen is introduced into 1L of oleum Olivarum at 20-26 deg.C and 1bar to total amount of 22 g.
A preparation method of a traditional Chinese medicine preparation widely used for gynecological inflammation comprises the following steps:
1) cleaning and drying 40g of phellodendron and 60g of matrine, and then crushing the phellodendron and the matrine to prepare a mixture;
2) mixing the mixture with 80% ethanol according to the mass ratio of 1:11 to obtain an extraction solution;
3) mixing the extractive solution with 1L oleum Olivarum, stirring, placing into a mixer, introducing medical oxygen into the mixer at 20-26 deg.C and 1bar, controlling flow at 4g/h and oxygen introduction time at 5.5 h. The Chinese medicine preparation widely used for gynecological inflammation is prepared.
Example 2
A traditional Chinese medicine preparation widely used for gynecological inflammation comprises the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 30g and matrine 50g, and the total amount of oxygen gas introduced into 1L of oleum Olivarum is 15g at 20-26 deg.C and 0.5 bar.
A preparation method of a traditional Chinese medicine preparation widely used for gynecological inflammation comprises the following steps:
1) cleaning 30g of phellodendron and 50g of matrine, drying, and then crushing to prepare a mixture;
2) mixing the mixture with 75% ethanol according to the mass ratio of 1:10 to obtain an extraction solution;
3) mixing the extractive solution with 1L oleum Olivarum, stirring, placing into a mixer, introducing medical oxygen into the mixer at 20-26 deg.C and 0.5bar, controlling flow at 4g/h and oxygen introduction time at 5 h. The Chinese medicine preparation widely used for gynecological inflammation is prepared.
Example 3
A traditional Chinese medicine preparation widely used for gynecological inflammation comprises the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 50g and matrine 70g, and oxygen is introduced into 1L of oleum Olivarum at 20-26 deg.C and 1.5bar to total amount of 24 g.
A preparation method of a traditional Chinese medicine preparation widely used for gynecological inflammation comprises the following steps:
1) 50g of phellodendron and 70g of matrine are cleaned, dried and then crushed to prepare a mixture;
2) mixing the mixture with 95% ethanol according to the mass ratio of 1:12 to obtain an extraction solution;
3) mixing the extractive solution with 1L oleum Olivarum, stirring, placing into a mixer, introducing medical oxygen into the mixer at 20-26 deg.C and 1.5bar, controlling flow at 4g/h and oxygen introduction time at 6 h. The Chinese medicine preparation widely used for gynecological inflammation is prepared.
The beneficial effects of the invention are as follows: the traditional Chinese medicine preparation widely used for gynecological inflammation achieves the effect of treating diseases, can achieve the effect of treatment after being externally applied, has mild medicine effect, no relapse after healing, no dependence, comprehensive effect and prominent effect.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Case 1:
after a Wuhan patient is aged 38 years old with certain Li and women suffering from pelvic inflammation for more than 4 years, the patient is painful, the fever symptom disappears, the appetite is obviously enhanced, and the facial complexion of the patient is ruddy and glossy. After one week of use, the patient experienced no pain in the lower abdomen during menstruation. After one treatment course, the patients have improved all aspects of the bodies and are full of energy. The examination of the ultrasonic B basin cavity is not carried out any inflammatory exudation.
Case 2:
liu somean, female, age 36, Anhui and fertile people. The infertility history is 7 years, and is accompanied by severe gynecological inflammation. After one month of use of a traditional Chinese medicine preparation widely used for gynecological inflammation, the gynecological inflammation basically disappears, and the menstruation of Liu is changed like a strange trace, and the curative effect is obvious. Persisting in use for three months, Liu somebody has been gestated for 8 months now, and is ready to be made into expectant mothers.
Case 3:
plum women, 28 years old, guangdong. In the early plum woman in 2015 2 months, a left labia minora is long, the surface is uneven, dirty gray, cauliflower-shaped is increased, the base part is gray black, and the texture is hard. The plum female then goes to a hospital for diagnosis and treatment, and the diagnosis is confirmed to be condyloma acuminatum. Topical injections of interferon were given after laser treatment, one at a time, for twenty total doses. Approximately twenty days after treatment, the disease recurred at the original lesion and some new warts appeared around the lesion. The plum lady cannot accept the situation and has a light idea. After one month, using a Chinese medicinal preparation widely used for gynecological inflammation, the wart body of the plum lady gradually decreases and shrinks and finally heals.

Claims (6)

1. The traditional Chinese medicine preparation widely used for gynecological inflammation is characterized by comprising the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 30-50g and matrine 50-70g, and the total amount of oxygen is 20-24g per 1L of oleum Olivarum at 20-26 deg.C and 0.5-1.5 bar.
2. The traditional Chinese medicine preparation widely used for gynecological inflammation according to claim 1, characterized by comprising the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 40g and matrine 60g, and oxygen is introduced into 1L of oleum Olivarum at 20-26 deg.C and 1bar to total amount of 22 g.
3. The traditional Chinese medicine preparation widely used for gynecological inflammation according to claim 1, characterized by comprising the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 30g and matrine 50g, and oxygen is introduced into 1L of oleum Olivarum at 20-26 deg.C and 0.5bar to total amount of 20 g.
4. The traditional Chinese medicine preparation widely used for gynecological inflammation according to claim 1, characterized by comprising the following raw materials in parts by weight: every 1L of oleum Olivarum contains cortex Phellodendri 50g and matrine 70g, and oxygen is introduced into 1L of oleum Olivarum at 20-26 deg.C and 1.5bar to total amount of 24 g.
5. The traditional Chinese medicine preparation for treating gynecological inflammation widely according to claim 1, wherein the flow rate is controlled to be 4g/h during the oxygen introducing process; the time of oxygen introduction is controlled to be 5-6 hours.
6. A preparation method of a traditional Chinese medicine preparation widely used for gynecological inflammation is characterized by comprising the following steps:
1) cleaning and drying 30-50g of phellodendron and 50-70g of matrine, and then crushing the materials to prepare a mixture;
2) mixing the mixture with 75-95% ethanol according to the mass ratio of 1:10-12 to obtain an extraction solution;
3) mixing the extractive solution with 1L oleum Olivarum, stirring, placing into a mixer, introducing medical oxygen into the mixer at 20-26 deg.C and 0.5-1.5bar, controlling flow at 4g/h and oxygen introduction time at 5-6 h. The Chinese medicine preparation widely used for gynecological inflammation is prepared.
CN201910377849.3A 2019-05-06 2019-05-06 Chinese medicinal preparation for treating gynecological inflammation and its preparation method Pending CN111888407A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101185702A (en) * 2006-11-16 2008-05-28 高建泉 Medicine for treating gynaecologic inflammation
CN102895524A (en) * 2012-09-28 2013-01-30 史培德 Combination medicine for treating gynecological inflammation
CN105770239A (en) * 2016-05-19 2016-07-20 庹朝彦 External health gel for treating gynecological inflammation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101185702A (en) * 2006-11-16 2008-05-28 高建泉 Medicine for treating gynaecologic inflammation
CN102895524A (en) * 2012-09-28 2013-01-30 史培德 Combination medicine for treating gynecological inflammation
CN105770239A (en) * 2016-05-19 2016-07-20 庹朝彦 External health gel for treating gynecological inflammation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
冯涤尘等: "《中国男科临床研究》", 31 December 1993, 中国中医药出版社 *
吴凌: "《舌尖上的食物：吃对了，全家健康》", 31 January 2016, 陕西科学技术出版社 *
柯铭清: "《中草药有效成分理化与药理特性》", 29 February 1980, 湖南科学技术出版社 *

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