CN111856054A - Multistage quantitative ring quantitative system - Google Patents
Multistage quantitative ring quantitative system Download PDFInfo
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- CN111856054A CN111856054A CN202010588465.9A CN202010588465A CN111856054A CN 111856054 A CN111856054 A CN 111856054A CN 202010588465 A CN202010588465 A CN 202010588465A CN 111856054 A CN111856054 A CN 111856054A
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- electromagnetic valve
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- ring
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1032—Dilution or aliquotting
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Analytical Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
A multi-stage quantitative ring quantitative system is used for automatically diluting a high-concentration sample or is used as a quantitative system of an instrument with larger quantitative volume span, and comprises a sampling tube, a sample inlet tube, a quantitative ring, a waste liquid tube, a diluent tube, an electromagnetic valve and a peristaltic pump; the system comprises a plurality of solenoid valves, wherein each solenoid valve comprises a common end C, a normally closed end NC and a normally open end NO; the NC end of the first electromagnetic valve is connected with the sampling tube, the NO end of the first electromagnetic valve is connected with the sampling tube, the common end C of the second electromagnetic valve is communicated with the NC end of the second electromagnetic valve through the first quantitative ring, the common end C of the second electromagnetic valve is communicated with the NC end of the third electromagnetic valve through the second quantitative ring, the operation is repeated until the common end C of the penultimate electromagnetic valve is communicated with the common end C of the last electromagnetic valve through the peristaltic pump, the NC end of the last electromagnetic valve is connected with the diluent tube, the NO ends of all the electromagnetic valves starting from the second electromagnetic valve are connected with the waste liquid tube, and the using number of the quantitative rings and the electromagnetic valves can be increased or decreased according to needs to meet the requirements of different.
Description
Technical Field
The invention belongs to the technical field of sample introduction quantification of automatic analyzers, and particularly relates to a multistage quantification loop quantification system.
Background
The sampling quantitative system is one of the most critical parts of an automatic analysis instrument, and the accuracy and the function of the sampling quantitative system are the basis for ensuring the performance of the whole instrument. The quantitative loop technology is one of the existing precise sampling technologies with good reproducibility
When an automatic analysis instrument is developed, a high-concentration sample is often required to be diluted or different samples with large volume difference are required to be quantified, for example, a single quantification ring or a quantification pump is used for quantification, so that the quantification precision of a large-volume sample and a small-volume sample is difficult to ensure at the same time, and the cost of the instrument is increased by using a plurality of single quantification ring systems or a plurality of quantification pumps for quantification.
Disclosure of Invention
The invention aims to provide a quantitative system of an automatic analysis instrument, which enables the automatic analysis instrument to automatically dilute a high-concentration sample or accurately quantify the sample with larger volume span.
In order to achieve the above object, the present invention provides a multi-stage quantitative ring quantitative system, which comprises a sampling tube, a sample feeding tube, a quantitative ring, a waste liquid tube, a diluent tube, an electromagnetic valve and a peristaltic pump; the system comprises a plurality of electromagnetic valves, wherein each electromagnetic valve comprises a common end C, a normally closed end NC and a normally open end NO; the NC end of the first electromagnetic valve is connected with the sampling tube, the NO end of the first electromagnetic valve is connected with the sampling tube, the common end C of the second electromagnetic valve is communicated with the NC end of the second electromagnetic valve through the first quantitative ring, the common end C of the second electromagnetic valve is communicated with the NC end of the third electromagnetic valve through the second quantitative ring, the connection mode is repeated, the common end C of the penultimate electromagnetic valve is communicated with the common end C of the last electromagnetic valve through the peristaltic pump, the NC end of the last electromagnetic valve is connected with the diluent tube, and the NO ends of all the electromagnetic valves starting from the second electromagnetic valve are connected with the waste liquid tube.
Further, all the solenoid valves of the multi-stage quantitative ring quantitative system can be replaced by a multi-way selector valve which at least has a common end and two branch holes which can be communicated with the common end.
Furthermore, the length, the pipe diameter and the material of each quantitative ring can be selected according to the property and the volume of the sample.
Drawings
FIG. 1 is a first embodiment of the present invention;
FIG. 2 is a second embodiment of the present invention;
in the figure: 1, 15-sampling tube; 2, 3-quantitative ring; 4, 16-sample tube; 5, 6, 7-waste pipe; 8-a diluent tube; 9, 10, 11, 12-solenoid valves; 13-a peristaltic pump; 14-common to the multi-way selector valves.
Detailed Description
The multi-stage quantitative loop quantitative system of the present invention will be described in detail with reference to the accompanying drawings.
Example one
Referring to fig. 1, the two-stage quantitative loop quantitative system provided by the present invention comprises a sampling tube (1), a sampling tube (4), quantitative loops (2, 3), waste liquid tubes (5, 6, 7), a diluent tube (8), solenoid valves (9, 10, 11, 12), and a peristaltic pump (13).
The system comprises a plurality of solenoid valves (9, 10, 11, 12), each solenoid valve comprising a common terminal C, a normally closed terminal NC and a normally open terminal NO; the NC end of the first electromagnetic valve (9) is connected with the sampling tube (1), the NO end is connected with the sampling tube (4), the common end C is communicated with the NC end of the second electromagnetic valve (10) through the first quantitative ring (2), the common end C of the second electromagnetic valve (10) is communicated with the NC end of the third electromagnetic valve (11) through the second quantitative ring (3), the common end C of the third electromagnetic valve (11) is communicated with the common end C of the fourth electromagnetic valve (12) through the peristaltic pump (13), the NC end of the fourth electromagnetic valve (12) is connected with the diluent tube (8), the NO ends of all the electromagnetic valves starting from the second electromagnetic valve are connected with the waste liquid tubes (5, 6 and 7), and the using number of the quantitative rings and the electromagnetic valves can be increased or decreased according to meet the requirements of different dilution multiples or quantitative volumes.
When the two-stage quantitative ring quantitative system is used as a quantitative dilution system, the quantitative dilution is carried out according to the following steps:
the fourth electromagnetic valve (12) is switched to a common end C to be communicated with an NO end, all the other electromagnetic valves (9, 10 and 11) are positioned at the common end C to be communicated with an NC end, the peristaltic pump (13) rotates anticlockwise to draw a sample from the sample inlet pipe (1) to fill the first quantitative ring (2), and then the peristaltic pump (13) stops rotating; the second electromagnetic valve (10) is switched to the common end C to be communicated with the NO end, the fourth electromagnetic valve (12) needs to be switched to the common end C to be communicated with the NC end, the other electromagnetic valves (9 and 11) are kept still, the peristaltic pump (13) rotates clockwise until the second quantitative ring (3) is filled with the diluent, and the peristaltic pump (13) stops rotating; the third electromagnetic valve (11) and the fourth electromagnetic valve (12) are switched to a common end C to be communicated with an NO end, the peristaltic pump (13) continues to rotate clockwise to discharge redundant diluent out of the system, and the peristaltic pump (13) stops rotating; and then the third electromagnetic valve (11) is switched to the public end C to be communicated with the NC end, the first electromagnetic valve (9) is switched to the public end C to be communicated with the sample inlet pipe (4) of the NO end, and the peristaltic pump (13) continues to rotate clockwise to pump the well-quantified sample and the diluent into the system.
If the samples with different volumes need to be quantified, the quantification with different volumes can be realized by the way of the quantification of the first quantification ring, the quantification of the first quantification ring + the second quantification ring or the quantification of the first quantification ring + the second quantification ring + … … + the nth quantification ring.
Example two
Compared with the first embodiment, the first solenoid valve (as shown in fig. 2) is replaced by the multi-way selector valve, the first quantitative ring is directly communicated with the common end (14) of the multi-way selector valve, and at least two branch holes on the multi-way selector valve can be respectively communicated with the sampling pipe (15) and the sample inlet pipe (16).
Claims (3)
1. A multi-stage quantitative ring quantitative system comprises a sampling tube, a quantitative ring, a waste liquid tube, a diluent tube, an electromagnetic valve and a peristaltic pump; the system comprises a plurality of electromagnetic valves, wherein each electromagnetic valve comprises a common end C, a normally closed end NC and a normally open end NO; the NC end of the first electromagnetic valve is connected with the sampling tube, the NO end of the first electromagnetic valve is connected with the sampling tube, the common end C of the second electromagnetic valve is communicated with the NC end of the second electromagnetic valve through the first quantitative ring, the common end C of the second electromagnetic valve is communicated with the NC end of the third electromagnetic valve through the second quantitative ring, the connection mode is repeated, the common end C of the penultimate electromagnetic valve is communicated with the common end C of the last electromagnetic valve through the peristaltic pump, the NC end of the last electromagnetic valve is connected with the diluent tube, and the NO ends of all the electromagnetic valves starting from the second electromagnetic valve are connected with the waste liquid tube.
2. The multi-stage dosing ring dosing system of claim 1, wherein: all solenoid valves of the multi-stage quantitative ring quantitative system can be replaced by a multi-way selector valve which at least has a common end and two branch holes which can be communicated with the common end.
3. The multi-stage dosing ring dosing system of claim 1, wherein: the length, the pipe diameter and the material of each quantitative ring can be selected according to the property and the volume of the sample.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010588465.9A CN111856054A (en) | 2020-06-24 | 2020-06-24 | Multistage quantitative ring quantitative system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010588465.9A CN111856054A (en) | 2020-06-24 | 2020-06-24 | Multistage quantitative ring quantitative system |
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| Publication Number | Publication Date |
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| CN111856054A true CN111856054A (en) | 2020-10-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202010588465.9A Pending CN111856054A (en) | 2020-06-24 | 2020-06-24 | Multistage quantitative ring quantitative system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116242688A (en) * | 2023-02-16 | 2023-06-09 | 广州伊创科技股份有限公司 | Quick dilution device for online analysis |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0755779A (en) * | 1993-08-19 | 1995-03-03 | Kawasaki Steel Corp | Managing method for neutral salt liquid of stainless steel plate manufacturing process |
| CN203688432U (en) * | 2013-12-17 | 2014-07-02 | 中兴仪器（深圳）有限公司 | Liquid metering system |
| CN106525506A (en) * | 2016-12-13 | 2017-03-22 | 浙江微兰环境科技有限公司 | System provided with double quantification rings |
| CN208076383U (en) * | 2018-04-27 | 2018-11-09 | 山东清锦环保科技有限公司 | Flow path and water quality on-line monitoring instrument |
| CN208140688U (en) * | 2018-04-27 | 2018-11-23 | 山东清锦环保科技有限公司 | Flow path and water quality on-line monitoring instrument |
-
2020
- 2020-06-24 CN CN202010588465.9A patent/CN111856054A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0755779A (en) * | 1993-08-19 | 1995-03-03 | Kawasaki Steel Corp | Managing method for neutral salt liquid of stainless steel plate manufacturing process |
| CN203688432U (en) * | 2013-12-17 | 2014-07-02 | 中兴仪器（深圳）有限公司 | Liquid metering system |
| CN106525506A (en) * | 2016-12-13 | 2017-03-22 | 浙江微兰环境科技有限公司 | System provided with double quantification rings |
| CN208076383U (en) * | 2018-04-27 | 2018-11-09 | 山东清锦环保科技有限公司 | Flow path and water quality on-line monitoring instrument |
| CN208140688U (en) * | 2018-04-27 | 2018-11-23 | 山东清锦环保科技有限公司 | Flow path and water quality on-line monitoring instrument |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116242688A (en) * | 2023-02-16 | 2023-06-09 | 广州伊创科技股份有限公司 | Quick dilution device for online analysis |
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