CN111840809A - Optical medical device - Google Patents
Optical medical device Download PDFInfo
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- CN111840809A CN111840809A CN202010714173.5A CN202010714173A CN111840809A CN 111840809 A CN111840809 A CN 111840809A CN 202010714173 A CN202010714173 A CN 202010714173A CN 111840809 A CN111840809 A CN 111840809A
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- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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- A61N5/06—Radiation therapy using light
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Abstract
The invention discloses an optical medical device which comprises a light source part and a power supply part, wherein the light source part is electrically connected with the power supply part, the light source part comprises base cloth, a connecting layer, a light source layer and a covering layer, the connecting layer is laminated on the base cloth, the light source layer is laminated on the connecting layer, the covering layer is of a light-transmitting structure and is laminated on the light source layer and covers the light source layer and the connecting layer, and the power supply part is used for lighting the light source layer. The light source layer adopted by the invention has the characteristics of good light-emitting uniformity, lightness and thinness, flexibility, stretchability and the like, and can be completely attached to the part of a patient to be treated with phototherapy, so that the problems that the existing optical medical device is inconvenient to wear, damages normal tissues and the like can be well solved, the design is more humanized, and the comfort and the safety of user experience are ensured.
Description
Technical Field
The invention relates to the technical field of optical medical treatment, in particular to an optical medical treatment device.
Background
Photodynamic therapy is a method for treating diseases by directly using light or using the combination of light and drugs, and is currently applied to clinical medicine. There are two main ways of photodynamic therapy, one is direct light therapy, and the other is light therapy and drug (also called photosensitizer) synergistic therapy. The direct light therapy is to directly irradiate the affected part with one or more kinds of light, and has the effects of sterilizing, disinfecting, promoting cell metabolism, promoting cell regeneration, promoting cell secretion of chemical substances (such as serotonin) and promoting blood circulation. The medical process of the synergistic effect of light and medicine is that the laser irradiation with specific wavelength excites the photosensitizer absorbed by the tissue, and the excited photosensitizer transfers the energy to the surrounding oxygen to generate singlet oxygen with strong activity, and the singlet oxygen and the adjacent biological macromolecules generate oxidation reaction to generate cytotoxicity effect, thereby causing cell damage and even death. At present, the phototherapeutic treatment can treat skin diseases such as herpes zoster, alopecia areata, phlebitis, erysipelas, acne, paronychia, chilblain and the like, surgical diseases such as wound infection, abscess, ulcer and the like, gynecological diseases such as chronic pelvic inflammatory disease, adnexitis, cervical erosion, leukoplakia vulvae and the like, internal diseases such as infantile diarrhea, ischemic heart disease, chronic gastritis and the like, and other diseases such as otorhinolaryngology department, burn department and the like.
The existing optical medical device is inconvenient to wear, and most of the optical medical devices can only be used in hospitals, so that a great deal of inconvenience is brought to patients, and meanwhile, the treatment cost of the patients is increased. In addition, the light medical device can damage normal tissues due to too strong power when treating diseases, and in addition, the light emitting uniformity of the light medical device is poor, so that the light medical device is not beneficial to the treatment of affected parts with large areas.
Disclosure of Invention
Therefore, the invention aims to solve the technical problems that the optical medical device in the prior art is inconvenient to wear, high in treatment cost, poor in light-emitting uniformity and not suitable for treating affected parts with large areas. To this end, the invention provides a photomedical device.
In order to achieve the purpose, the invention adopts the following technical scheme:
the light medical device comprises a light source part and a power supply part, wherein the light source part is electrically connected with the power supply part, the light source part comprises a base cloth, a connecting layer, a light source layer and a covering layer, the connecting layer is laminated on the base cloth, the light source layer is laminated on the connecting layer, the covering layer is of a light-transmitting structure, is laminated on the light source layer and covers the light source layer and the connecting layer, and the power supply part is used for lighting the light source layer.
Furthermore, an integrated structure is formed between the power supply part and the light source part, or the power supply part and the light source part are in an independent arrangement structure, and the power supply part and the light source part are electrically connected through a transmission line; the power supply part comprises a power supply part body and a power supply module arranged on the power supply part body, a controller is further arranged on the light source part or the power supply part, and the controller is respectively electrically connected with the power supply module and the light source layer and is used for adjusting the light-emitting wavelength, the time and the brightness of the light source layer.
Or further, the light source part also comprises a wireless power supply chip, and the power supply part is connected with the light source part through wireless power supply; the power supply part is an intelligent terminal, the light source part or the power supply part is also provided with a controller, and the controller is respectively electrically connected with the power supply part and the light source part and is used for adjusting the light-emitting wavelength, time and brightness of a light source layer in the light source part.
Still further, still be equipped with between the light source layer and the articulamentum and be used for detecting the light source layer luminous temperature's first temperature sensor, first temperature sensor respectively with the controller is connected, the controller configuration is used for receiving and judges when the temperature signal that first temperature sensor detected is higher than the temperature setting value, control the light source layer cooling.
Furthermore, a sensor group is arranged on the covering layer and comprises a second temperature sensor for detecting the temperature of the affected part to be phototherapy, a first sensor for detecting body signals of the part to be phototherapy and a second sensor for detecting biochemical index signals of the part to be phototherapy; the second temperature sensor, the first sensor and the second sensor are respectively connected with the controller and the power supply part; the controller is used for formulating and/or changing the parameters of the medicine related to the light source layer or the affected part to be phototherapy according to the detection signals of the second temperature sensor, the first sensor and the second sensor.
Preferably, the covering layer is a fabric layer with transmittance greater than 1% and is used for controlling the light dose and temperature of the light emitted from the covering layer;
one or more of silver ions, silver nanowires, iodide ions, a photosensitizer and a drying agent are doped in the covering layer, and the side surface of the covering layer, which is attached to a part to be phototherapeutic, is of a concave-convex structure or an arched structure;
or the covering layer comprises a drug care layer and a sweat guide layer stacked on the outer side of the drug care layer, the drug care layer is stacked on the light source layer and is a packaging base material doped with one or more of silver ions, silver nanowires, iodide ions and a photosensitizer, a drying agent is arranged in the packaging base material, and a plurality of air holes communicated with the drying agent are formed in the packaging base material; the sweat guide layer is of a concave-convex structure or an arch structure.
Preferably, the light source unit further includes an isolation layer stacked between the cover layer and the light source layer, scattering particles may be disposed in the isolation layer, the isolation layer is an indium tin oxide coating or an aerogel material, and the scattering particles are made of TiO2Particles, ZrO2Particles, SiO2Particles, SiO particles, TiO particles.
The photomedical device is also provided with a protective layer, the protective layer is arranged on the covering layer, and the protective layer can be taken down when the photomedical device is used.
The light source layer includes: the LED lamp comprises a flexible substrate and a plurality of LED lamp beads arranged on the flexible substrate;
or, the light source layer is a flexible OLED screen body; the controller controls the light source layerThe light emission wavelength ranges from 260nm to 1018nm, preferably from 260nm to 460nm and from 590nm to 810 nm; the irradiation power density of the light source layer is 1000mW/cm2Below, 1mW/cm is preferable2-100mW/cm2。
In specific application, two ends of the base cloth are provided with a fitting structure I for fixing the light source part on a part to be phototherapy; the power supply part is provided with a fitting structure II, so that wearing and power supply are facilitated.
Compared with the prior art, the technical scheme of the invention has the following beneficial effects:
A. the connecting layer is provided with the light source layer, and the light source layer has the characteristics of good light-emitting uniformity, light weight, flexibility, stretchability and the like, so that the part of a patient to be treated with phototherapy can be completely attached, and the light source layer is easy to prepare into a wearable photomedical device.
B. According to the invention, the isolation layer and/or the covering layer is arranged on the light source layer, the covering layer is in contact with the part to be phototherapy, the covering layer comprises the sterilization layer and drying structures for absorbing sweat, sweating and the like, the condition of the phototherapy part can be obtained according to the detection signals of the second temperature sensor, the second sensor, the first sensor and other sensors, the detection data of the phototherapy part can be displayed through the light source part or the intelligent terminal, the phototherapy condition can be reflected quickly and timely, and the wavelength, time and brightness of the medicine or the light source layer at the phototherapy part can be established and/or adjusted in real time.
C. Because the disease treatment cycle is long and many patients need to go to hospitals for medical treatment, the light medical treatment device can be used for home treatment without influencing normal life and work. The sensor can real-time supervision phototherapy required parameter and transmit to the controller, provides the basis for the regulation of illumination intensity.
D. The power supply part and the light source part are designed separately, and the middle part of the power supply part and the light source part are connected by a transmission line or an intelligent terminal in a wireless power supply way; two parts are dressed respectively, and light source portion dresses treating the phototherapy affected part, and power portion can laminate in light source portion or directly dress on the human body or wear on the clothes, and it is more convenient to use and carry.
E. The power supply part and the light source part adopted by the invention can be integrated together, the light source part and the power supply part are both arranged on the same base cloth, the power supply part and the light source part are connected through a lead, the power supply part can directly supply power to the light source part, the lighting wavelength, the brightness and the time length of the light source part are realized by controlling a switch on the power supply part, the wearing is convenient, the using volume is reduced, and the convenience is further promoted.
F. The invention firstly detects whether the light emitting temperature of the light source layer is normal through the first temperature sensor, the light source layer can be normally opened when the light emitting temperature is detected within the normal temperature range, then the temperature of the affected part of the skin is further detected through the second temperature sensor, the temperature of the light source layer is required to be adjusted or the light medical device is directly closed when the temperature is higher than the set temperature, the light medical device normally carries out phototherapy on the skin of the affected part when the skin temperature at the position where the light medical device is attached is detected to be lower than the set value, and the light emitting temperature of the light source layer and the skin temperature at the position where the light medical device; meanwhile, whether infection exists on the affected part is monitored through the pH sensor, the light-emitting wavelength of the light source layer is adjusted through the controller according to the infection condition of the affected part, and the pH value of the affected part is controlled within a certain range. Under guaranteeing the affected part normal conditions, through pressure sensor monitoring affected part pressure value, according to the illumination intensity of affected part pressure value adjustment light source layer, keep the phototherapy effect in affected part, avoid the patient that burns.
Drawings
FIG. 1 is a cross-sectional view of a photomedical device provided in example 1 of the invention;
fig. 2 is an expanded schematic view of a power supply unit provided in embodiment 1 of the present invention;
fig. 3 is a functional block diagram of the control of the photomedical device provided in embodiment 1 of the invention;
fig. 4 is a structure diagram of a plurality of light sources assembled in embodiment 1 of the present invention;
fig. 5 is a structural diagram of a light source layer provided in embodiment 1 of the present invention;
FIG. 6 is a view showing the structure of a cover layer provided in example 1 of the present invention;
FIG. 7 is a top view of a photomedical device provided in example 1 of the invention;
fig. 8 is a first integrated configuration diagram of a light source section and a power supply section provided in embodiment 2 of the present invention;
fig. 9 is a second integrated configuration diagram of the light source section and the power supply section provided in embodiment 2 of the present invention;
fig. 10 is a structural view of a wireless power supply chip provided in a light source unit according to embodiment 3 of the present invention;
FIG. 11 is a cross-sectional view of a photomedical device provided in accordance with example 4 of the invention;
fig. 12 is a structure diagram of a concave-convex surface of a covering layer provided in embodiment 4 of the present invention;
FIG. 13 is a schematic view of the surface of the covering layer provided in example 4 of the present invention in an arch configuration;
FIG. 14 is a cross-sectional view of a photomedical device provided in accordance with example 5 of the invention;
fig. 15 is a functional block diagram of the control of the photomedical device provided by embodiment 6 of the invention;
fig. 16 is a functional block diagram of the control of the photomedical device provided by embodiment 7 of the invention;
FIG. 17 is a block diagram of the control logic for the photomedical device of the present invention;
fig. 18a, 18b and 18c are illustrations of specific application examples of the wearable photomedical device provided by the invention.
Description of reference numerals:
10-light source part
101-base cloth, 1011-fitting structure I; 102-a tie layer; 103-a light source layer, 1031-a first temperature sensor, 1032-a wireless power supply chip; 104-an isolation layer; 105-cover, 1051-drug care layer, 1052-wicking layer, 1053-desiccant, 1054-vent, 1052 a-second temperature sensor, 1052 b-first sensor, 1052 c-second sensor; 106-protective layer.
20-Power supply section
201-a power supply part body, 202-a power supply module, 203-a phototherapy module, 204-a charging port, 205-a power switch, 206-a screen brightness adjusting knob, 207-a fitting structure II, 208-a communication module and 209-a display module.
30-telescopic transmission line
301-connecting port
40-controller, 401-main control module, 402-instruction identification module, 403-voice playing module a-concave-convex structure, b-arched structure
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
This invention may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete and will fully convey the concept of the invention to those skilled in the art, and the present invention will only be defined by the appended claims. In the drawings, the size and relative sizes of layers and regions may be exaggerated for clarity. It will be understood that when an element such as a layer, region or substrate is referred to as being "formed on" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. In contrast, when an element is referred to as being "directly formed on" or "directly disposed on" another element, there are no intervening elements present.
In addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
Example 1
As shown in fig. 1 and 18b, the present invention provides a photomedical device, which includes a light source unit 10 and a power supply unit 20, wherein the light source unit 10 is connected to the power supply unit 20, the light source unit 10 sequentially includes a base cloth 101, a connecting layer 102, a light source layer 103 and a covering layer 105, the connecting layer 102 is laminated on the base cloth 101, the light source layer 103 is laminated on the connecting layer 102, the covering layer 105 is a light-transmitting structure, is laminated on the light source layer 103 and completely covers the light source layer 103 and the connecting layer 102, and the power supply unit is used for lighting the light source layer to perform phototherapy treatment on an affected part of a body; the cover layer 105 is preferably of a heat-insulating and light-transmitting structure, and is made of heat-insulating transparent fabric, the transmittance of the fabric layer is greater than 1%, preferably greater than 85%, and the light dose and the temperature can be controlled by controlling the transmittance of the cover layer 105. The light source layer 103 is one or a combination of more of an OLED, a micro-OLED, an LED, a mini LED and a micro LED.
When the power supply part 20 and the light source part 10 are in an independent structure, the power supply part and the light source part are electrically connected through a transmission line; when the power supply unit 20 and the light source unit 10 are connected by the retractable transmission line 30, both ends of the retractable transmission line 30 are detachably connected to the connection ports 301 provided in the power supply unit 20 and the light source unit 10, respectively. When the distance between the light source 10 and the power source 20 needs to be changed, the length of the retractable transmission line 30 can be directly adjusted, so that the wires inside the light source 10 and the power source 20 are prevented from being pulled, and the service life is prolonged. In this embodiment, the retractable transmission line 30 is an automatic retractable winder, or a spring wire transmission line, and the power supply unit can be fixed on the body or on the clothes worn by the body, or the power supply unit can be disposed on other supports outside the body, such as other medical devices, for example, a bone fixing support, a bandage, etc., and the specific installation position of the power supply unit is not limited in the present invention. As shown in fig. 2 and 3, the power supply part 20 includes a power supply part body 201 and a power supply module 202 disposed on the power supply part body 201, and preferably, in order to better control the light emitting wavelength, time and brightness of the light source layer, a controller 40 is further disposed on the power supply part 20; the power module 202 is used to supply power to the light source layer 103 and the controller 40. Of course, the controller 40 may be disposed on the light source section 10 to directly control the light source layer 103 on the light source section 10, and the light emitting wavelength, time, and brightness of the light source layer 103 may be adjusted in the same manner.
The controller 40 controls the light emitting wavelength, time and brightness of the light source layer 103 according to the phototherapy condition of the phototherapy part, so as to realize phototherapy on the affected part of the body. Because light source portion adopts single flexible OLED or can stretch OLED or set up a plurality of LED lamp pearls on a plurality of flexible OLED screen bodies or the flexible base plate, consequently, can realize the phototherapy to plane skin and the circular arc skin position on the health. As shown in fig. 4, if the area of the affected part is large, a large-area light source layer can be formed by splicing a plurality of flexible OLED screens or a plurality of LED beads, and the light source layer is controlled to perform phototherapy on the affected part at the same time.
Further preferably, in order to facilitate real-time monitoring of phototherapy conditions at an affected part, as shown in fig. 5, a first temperature sensor 1031 for detecting light emitting temperature of the light source layer 103 is disposed between the light source layer 103 and the connection layer 102, when the temperature of the light source layer 103 monitored by the first temperature sensor 1031 is higher than 40 ℃, the first temperature sensor 1031 transmits a signal to the controller, and the controller automatically implements cooling processing, such as controlling the light source layer 103 to be turned off or reducing brightness of the light source layer 103 or turning on other devices for dissipating heat for cooling; as shown in fig. 6, a second temperature sensor 1052a for detecting the temperature of the affected part to be phototherapy, a first sensor 1052b for detecting a body signal of the affected part to be phototherapy, and a second sensor 1052c for detecting a biochemical index signal of the part to be phototherapy are further disposed on one side of the covering layer 105 away from the light source layer 103, the first sensor can acquire signals of heat, sound, light, electricity, and force of the body, such as electrocardio, electroencephalogram, electrooculogram, myoelectricity, blood oxygen, and blood pressure, preferably a pressure sensor for monitoring the swelling degree of the part to be phototherapy is employed, the second sensor can acquire index signals of glucose, lactic acid, and uric acid of the part to be phototherapy, and after the controller receives the signals, the controller formulates and/or changes the light source part or the medicine related to be phototherapy, preferably a pH sensor; the second temperature sensor 1052a may be placed in the center or edge of the light source layer 103 or other location, the first sensor 1052b may be placed in the effective treatment area, and may be a plurality of pressure sensors, and the pH sensor (the sensor disclosed in Chen X, Wo F, Jin Y, et. Power module 202 is used to power light source layer 103, first temperature sensor 1031, second temperature sensor 1052a, first sensor 1052b, second sensor 1053b, and controller 40; the controller 40 is configured to adjust the light emitting wavelength, time and brightness of the light source layer 103 and the medication related parameters of the phototherapy region by using automatic and/or manual input signals according to the detection signals of the first temperature sensor 1031, the second temperature sensor 1052a, the first sensor 1052b and the second sensor 1052 c.
The first temperature sensor and the second temperature sensor are both connected to a controller, and the controller is configured to receive and determine that the temperature signal detected by the first temperature sensor is higher than a temperature set value, and reduce the brightness of the light source layer 103 or disconnect the power supply of the light source layer 103. Meanwhile, when the controller detects that the temperature signal detected by the second temperature sensor is higher than a normal value, the controller controls the light source layer 103 to emit light with corresponding wavelength for sterilization and the like. When the temperature of the light source portion rises above a suitable value due to some abnormal reasons, the controller 40 automatically reduces the brightness and power of the light source layer 103, and even directly shuts down the light source portion, so as to protect the health of the user and the light source layer 103. The temperature sensors are all in the prior art, and are not described in detail herein.
The controller is configured to receive and judge that the pressure signal detected by the pressure sensor is higher than or lower than a pressure set value, and increase/decrease the brightness of the light source layer. As shown in fig. 3, it is needless to say that the power supply unit 20 may further include a communication module 208; the communication module 208 is configured to transmit the signal detected by the sensor to the intelligent terminal, so that a user can know relevant conditions on the intelligent terminal. The communication module can be, for example, a mobile communication module such as GSM, CDMA, etc., or a short-distance wireless communication module such as a WIFI module or a bluetooth module, etc., and the intelligent terminal can be, for example, a mobile phone, a PAD, etc.
The pressure sensor can reflect the swelling degree of the affected part to a certain extent, and usually, before formal start of phototherapy, the light source part is fixed at a non-swelling position for initial pressure measurement; and fixing the light source part on the affected part to be phototherapy to detect pressure, and setting the brightness of the screen body according to the difference value between the detected pressure and the initial pressure as a parameter. The controller can adjust the voltage or current or duty ratio of the light source layer to make the screen brighter during phototherapy. In this embodiment, the first sensor may be selected from various pressure sensors with suitable dimensions, such as those disclosed in Manik Dautta et al, Multi-Functional Hydrogel-interlayer RF/NFC detectors as a Versatile Platform for Passive and WirelessBiosensing, adv.Electron.Mater.2020, 1901311; in other embodiments of the present application, other sensors may be used.
As shown in fig. 17, the first temperature sensor first detects whether the temperature of the light source layer is normal, if not, the entire photomedical device is directly turned off, and if so, the timer, the sensors and the light source layer start to operate, and the temperature of the light source layer is monitored in real time. And when the timing time is 15-60 min, closing the optical medical device. When the second temperature sensor detects that the skin temperature is higher than 40 ℃, the temperature of the OLED light source layer is reduced or the optical medical device is turned off, and when the skin temperature is lower than 40 ℃, the optical medical device works normally, and the skin temperature is monitored in real time. Whether there is infection in the affected part of pH sensor monitoring simultaneously, can open blue light or near ultraviolet after the pH value that surveys is higher than a definite value and disinfect to the affected part, blue light or near ultraviolet open can carry out pH value detection again after 5min ~ 15min, perhaps pH sensor real-time supervision affected part's pH value, when pH value is in a certain extent, pressure sensor begins work, when pressure is higher than a definite value, the illumination intensity of light source layer risees, can carry out pressure value detection again after 5min ~ 15min, perhaps pressure sensor real-time supervision affected part's pressure value, when the pressure value is in a certain extent, the sensor can carry out other detections to the affected part, when all belonging to a certain extent, the light source layer is normally bright. Of course, the types of sensors may be increased or decreased, and the detection sequence may be changed, depending on the disease to be treated.
The cover layer 105 of the present invention has a single-layer structure and is directly prepared from a polyurethane resin, polyethylene, PVP, or the like. The special excitation effect can be achieved by doping different particles, the functions of filtering and the like can be realized by changing the transmission spectrum of light, and the covering layer is doped with silver ions or silver nanowires or iodide ions or photosensitizer and the like, so that the covering layer 105 has a certain sterilization effect. In order to make the cover layer 105 have the sweat guiding performance, some desiccant components can be doped in the cover layer to achieve the sweat absorbing effect, and the cover layer 105 can be directly made into a concave-convex structure or an arched structure to have the sweat guiding function. According to the condition of different affected parts, the overburden can also be as packaging substrate, can hold different medicines in it, and the medicine is as the consumptive material, needs the periodic replacement, and the medicine in it can be put into packaging substrate in advance.
The base fabric 101 of the present invention serves as a support for the entire light source unit, and has elasticity that makes wearing more comfortable and porosity that ensures ventilation and heat dissipation of the device, and may be formed of any suitable nonwoven fabric including, but not limited to, spunlace, spunbond, thermal bond, wet laid nonwoven fabric, any suitable synthetic fiber may be used to produce spunlaced nonwoven fabric including polyalkylene, polyurethane, polypropylene, polyethylene terephthalate, nylon, etc., any thermal bond nonwoven fabric is a fabric produced by melting thermoplastic powder or fiber (including polyester, polypropylene, and polyethylene terephthalate fiber) using heat and many wet laid nonwoven fabrics are made of wood pulp or other natural fiber mixed with synthetic fiber, PU tape, zinc oxide tape, etc.
As shown in fig. 7, in order to make the whole optical medical device have a wearable function, the present invention provides a base cloth 101 with a fitting structure I1011, such as a magic tape structure or a coating adhesive layer or a magnetic device disposed at two ends of the base cloth 101, for fixing the light source part 10 on the affected part to be phototherapy, the adhesive layer may be a pressure sensitive adhesive, including a pressure sensitive adhesive biocompatible with human skin, including a water-soluble and water-insoluble pressure sensitive adhesive and a pressure sensitive adhesive dispersible in water-containing environment, and may also be a resin, rubber or PU adhesive, the invention also provides a fitting structure II207 on the power source part body 201, for example, one of a magic tape, an adhesive layer and a magnetic device is provided at two ends thereof, for wearing the power source part on the body or on clothes, the power supply unit main body 201 is also provided with a charging port 204 and a power switch 205 electrically connected to the power supply module 202.
The connecting layer 102 arranged on the base cloth can be formed by metal, inorganic materials, rubber materials and the like or directly formed by the rubber materials, the rubber materials are prepared by materials such as rubber or resin and the like, and can also be prepared by mixing with metal particles; metals such as gold, silver, copper, aluminum, etc.; the inorganic material such as graphene, the connection layer is adhered to the base fabric 101, and can also conduct heat generated by the OLED light source layer.
The light source layer 103 arranged on the connecting layer 102 can be provided with different flexible OLED screen bodies and LED lamp bead sizes according to different affected part areas and can be used as a light source for optical medical treatment, the light source layer consisting of one or more of a plurality of OLEDs, micro-OLEDs, LEDs, mini LEDs and micro LEDs can realize multi-dimensional bending, the light emitting wavelength of the light source layer is one or more light combinations in 260 nm-1018 nm, and ultraviolet rays in the wavelength range of 260 nm-440 nm can sterilize and disinfect the surface of skin, promote vasodilatation and dredge the blood sugar content; the blue light irradiation of the wave band of 440 nm-510 nm can be used for relieving pain and swelling caused by inflammation; the irradiation depth of the yellow green light with the wave band of 510 nm-590 nm is between the blue light and the red light, so that the dredging and the expansion of the capillary vessel in the skin depth can be promoted, the resistance of cells is enhanced, and the treatment effect of the affected part is accelerated. Red light with a waveband of 590 nm-810 nm can enable mitochondria to release cytochrome c oxidase, increase adenosine triphosphate, and cells provide energy by utilizing the adenosine triphosphate, so that the metabolism of the cells is promoted; meanwhile, the red light irradiation heats molecules in the blood vessel, so as to adjust the blood vessel expansion and improve the blood circulation; red in wave band of 810 nm-1018 nmThe external line can heat deep part of skin to promote blood circulation. When the light source layer capable of emitting light with corresponding wavelength is selected for the light medical device provided by the invention, the light medical device can generate corresponding phototherapy effect. The light-emitting wavelength of the light source layer is realized by selecting functional materials of the light-emitting layer, various combinations can be realized by selecting different functional materials through different pixel points, and the selection of the functional materials belongs to the prior art and is not repeated herein. In theory, various light source layers made of existing and future light emitting layer functional materials can be used in this embodiment; various medically approved or future approved wavelengths of phototherapy capable of treating disease may be used in this embodiment. For the present research results, the preferred emission wavelengths are 260nm to 460nm and 590nm to 810 nm; the irradiation power density of the luminous irradiation dose is 1000mW/cm under the brightness of 50nit-10000nit2Hereinafter, it is preferable to use 1mW/cm2-100 mW/cm2The OLED screen body is composed of an anode, a hole injection and transmission layer, a luminescent layer, an electron injection and transmission layer, a cathode, a thin film package and a sticking film.
Example 2
The present embodiment provides an optical medical device, and the main structure of the light source portion is the same as that of embodiment 1, and the description of the same parts is omitted. The present embodiment is different from embodiment 1 in that:
as shown in fig. 8, the power supply unit 20 is integrated with the light source unit 10, the light source unit 10 and the power supply unit 20 are both disposed at the same position of the base fabric 101, the power supply unit is a paper battery, the power supply unit 20 can directly supply power to the light source unit 10, the light source unit 10 is turned on by controlling a switch on the power supply unit 20, and the power supply unit 20 and the light source unit 10 are connected by a wire.
In addition, the light source unit 10 and the power source unit 20 may be directly attached to each other, as shown in fig. 9, the power source unit 20 is disposed on the outer side of the base fabric 101, the two units may be connected by a wire, the controller is disposed on the power source unit 20 or the light source unit 10, and the light emitting wavelength, time, and brightness of the light source layer may be adjusted by adjusting the controller.
For the above integration manner, the present invention may only set the attaching structure I on the base cloth 101 of the light source portion 10, and directly attach the base cloth 101 to the skin around the position requiring phototherapy, and the detailed structure is not described again.
Example 3
The present embodiment provides an optical medical device, and the main structure of the light source portion is the same as that of embodiment 1, and the description of the same parts is omitted. The present embodiment is different from embodiment 1 in that:
as shown in fig. 10, a wireless power supply chip 1032 is added to the light source unit 10, the power source unit 20 is connected to the light source unit 10 through wireless power supply, for example, the light source is bound to an FPC, the FPC is connected to an NFC coil, the power source unit is preferably an NFC smart terminal, the NFC smart terminal can light a light source layer when placed on the NFC coil, and after the power source unit 20 is directly attached to the light source unit 10, wireless power supply of the light source unit by the mobile terminal can be achieved without a wire. The controller for adjusting the light emitting wavelength, time and brightness of the light source layer may be disposed in the power supply portion or the light source portion. The wireless connection technology and the wireless power supply technology are mature communication technologies, and detailed description thereof is omitted.
Based on above-mentioned power supply unit 20 and light source unit 10 adopt the wireless power supply mode, be equipped with on the base cloth 101 of light source unit 10 and be used for the laminating outside the laminating structure I of affected part, can also set up laminating structure II on power supply unit 20 for power supply unit 20 laminates on light source unit 10 or dresses on the health or wears on the clothing, is convenient for realize dressing and power supply.
Example 4
This example provides a photomedical device, and the main body portion is the same as in examples 1, 2, and 3, and the description of the same portions will be omitted. The present embodiment is different from embodiment 1 in that:
in the embodiment, as shown in fig. 11, the light source unit 10 further includes an isolation layer 104 disposed between the cover layer 105 and the light source layer 103, the isolation layer 104 may be made of ito paint, aerogel, etc., and is used to separate the light source layer 103 from the cover layer 105 and transmit heat of the light source layer 103 to the cover layer 105 side, and scattering particles, such as TiO, may be mixed into the ito paint and the aerogel2Particles, ZrO2Particles, SiO2Particles, SiO particles, TiO particlesAt least one of the particles is used to improve the light output rate and the light emitting uniformity of the light source layer 103, and the light dose and the temperature of the light emitted from the isolation layer can be controlled.
Meanwhile, the covering layer 105 preferably adopts a double-layer structure and comprises a drug care layer 1051 and a sweat guide layer 1052 which are combined together, the drug care layer 1051 is arranged on the light source layer 103, the drug care layer 1051 is prepared by mixing silver ions such as polyurethane resin, polyethylene and PVP, or silver nanowires, or iodide ions, or photosensitizer, so that the covering layer 105 has a certain sterilization effect, meanwhile, the drug care layer 1051 can be used as a packaging base material, a transparent drying agent 1053 is filled in the packaging base material, and a plurality of air holes 1054 communicated with the drying agent 1053 in the drug care layer 1051 are arranged on the packaging base material; sweat guide layer 1052 is prepared from polyurethane, carboxylated butadiene styrene rubber, polyester, polyacrylate, polyethylene, PVP and the like, silver ions or silver nanowires or iodide ions or photosensitizer and the like to form a sterilization layer or a medicine layer. For example, the sweat-conductive layer 1052 is prepared by immersing a substrate made of polyurethane, carboxylated butadiene styrene rubber, polyester, polyacrylate, polyethylene, PVP, fiber, or the like in a photosensitizer solution and then drying the substrate, or by coating the photosensitizer directly on the substrate, and the photosensitizer may be in the form of one of a solution, a gel, a paste, a cream, and a powder. In addition, the photosensitizer such as liquid and colloid can be dipped with 1052 before use. The sweat-guiding layer 1052 has a concavo-convex structure or an arched structure, as shown in fig. 12 and 13, to achieve the function of guiding sweat.
Example 5
This example provides a photomedical device, and the main part is the same as in example 4, and the description of the same parts is omitted. This embodiment is different from embodiment 4 in that:
as shown in fig. 14, the present invention further provides a protective layer 106 on the photomedical device, and the protective layer 106 completely covers the cover layer 105 on the base fabric 101. The protective layer may be constructed of any suitable material including, but not limited to, polyethylene, polypropylene, kraft paper, polyester, Polystyrene (PS), High Impact Polystyrene (HIPS), or a composite of any of these materials. In use of the phototherapeutic device, the protective layer 106 can be removed and the phototherapeutic device can then be secured to the site to be phototherapeutic.
Example 6
This example provides a photomedical device, and the main body portion is the same as in example 5, and the description of the same portions is omitted. This embodiment is different from embodiment 5 in that:
the photomedical device shown in fig. 15 further includes a display module 209 provided on the power supply section body 201; the display module 209 includes a display screen; the first temperature sensor, the second temperature sensor, the first sensor and the second sensor transmit the detection signals to the controller 40, and the controller 40 controls the display module 209 to display the sensor detection data.
In this embodiment, the power supply main body 201 is further provided with a screen brightness adjusting knob 206, so that a user can manually adjust the brightness adjusting knob 206 of the light source layer 103 according to data displayed by the display module 209, or medical detection data (such as leukocyte concentration detected by blood routine items), or a result obtained by direct observation (such as swelling degree) to transmit a manual input signal to the controller 40, and the controller 40 adjusts the brightness of the light source layer 103 according to the manual input signal.
In the present invention, the brightness adjustment of the light source layer is realized by adjusting the operating voltage or current of the light source layer, and the voltage or current of the driving power supply of the light source layer can be directly adjusted regardless of manual adjustment or controller control adjustment.
Example 7
This example provides a photomedical device, and the main body portion is the same as in example 6, and the description of the same portions is omitted. This embodiment is different from embodiment 6 in that:
as shown in fig. 16, the power supply unit 20 of the present invention further includes a phototherapy module 203; the phototherapy module 203 includes a light source with adjustable brightness.
In the present embodiment, the phototherapy module 203 may be provided with a sensor separately with reference to the light source unit, and the controller 40 may adjust the brightness of the phototherapy module 203 according to a signal detected by the sensor; the screen brightness adjusting knob can be independently arranged to manually adjust the screen brightness.
The controller 40 in the above embodiments includes a main control module 401, an instruction recognition module 402, and a voice playing module 403; an instruction identification module 402 configured to respond to and identify an external signal instruction; a voice playing module 403 configured to respond to a playing instruction sent by the main control module; the main control module 401 is specifically configured to: when the result of the external signal instruction is the report position, the main control module 401 controls the voice playing module to start and send an alarm sound. When equipment in communication connection with the main control module, such as a mobile phone, sends an external signal instruction to the controller, the main control module receives the external signal instruction and controls the voice playing module to send out an alarm sound.
The following therapeutic applications of the photomedical device provided in example 7 for chilblain, wounds, arthritis and large areas of affected parts are described.
Application example 1
As shown in FIG. 18a, the wearable glove for treating chilblain is designed according to the present application example, the light source layer is adjusted to emit light with a wavelength of 260nm to 1018nm, preferably 600nm to 700nm, and the irradiation power density of the light source layer is 0.1mW/cm at a luminous intensity of 50nit to 20000nit2-1000mW/cm2。
Through distributing each phototherapy device in each finger department, be located the palm position and be power module and controller, power module provides the power for each light source layer, and the controller is controlling the light source portion on every finger respectively, and light source portion in the whole gloves also can be through power source interface direct power supply, and this gloves still have the heat preservation effect simultaneously. The power interface on the glove can be directly connected with a common mobile phone charger for use, and directly charges the power module or directly supplies power to the light source layer in the light source part.
The scheme can also be used for socks, leg sleeves, arm sleeves and the like for treating chilblain at home.
Application example 2
As shown in fig. 18b, the flexible wearable photomedical device for treating wounds provided by the present application example adjusts the wavelength of the emitted light of the light source layer to 280nm to 460nm for sterilization; the wound healing can be promoted at a wavelength of 580nm to 1100nm, and the light emission luminance is not limited herein.
In fig. 18b, for the treatment of finger wounds (similar to the function of a band-aid), the power supply part is fixed on the wrist part, and the light source part is wound on the affected part of the thumb, so that phototherapy of the finger partial wounds can be realized. When the phototherapy is performed, the controller adjusts the light-emitting wavelength and the brightness of the light source part, and the phototherapy function for a long time or a fixed time can be realized by setting the time. Because of the high homogeneity of light source layer, and the low nature that generates heat in the course of the work, avoided causing amazing and thermal injury to the affected part, and the disconnect-type design of power module and light source layer is fixed in wrist department, has guaranteed the portability of light medical treatment device, and treatment at home, and can not influence normal life work.
Application example 3
As shown in fig. 18c, the flexible wearable photomedical device for treating arthritis provided by the present application example adjusts the light source layer to emit one or a combination of lights with wavelengths of 260nm to 1018 nm; preferably, the light-emitting wavelength of the light-emitting layer is 590nm to 810nm, and the irradiation power density of the light-emitting layer under the brightness of 50nit to 10000nit is 0.1mW/cm2-50mW/cm2。
In fig. 18c, the power supply unit is fixed to the arm and the leg for treatment of the wrist, the ankle, and the toe. Fig. 18c shows a power supply part wound around the leg and a light source part wound around the bare joint, which can realize phototherapy of arthritis symptoms at the bare joint. The wavelength and the brightness of the light source layer are adjusted through a controller or a screen brightness adjusting knob, and targeted phototherapy is performed.
Application example 4
The invention can also realize phototherapy of a large area of affected parts, and can carry out targeted phototherapy on symptoms such as arthritis, wounds or chilblain and the like generated at the parts. When carrying out the phototherapy to the local affected part under the great area, for example certain affected part of upper part of the body, directly with the direct attached and bonding of the base cloth of light source portion and the power supply portion body of power supply portion on the health, also can fix power supply portion on user's clothes, can be through the luminous wavelength and the luminance of intelligent terminal direct control light source layer, especially adapted treatment at home.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the invention.
Claims (10)
1. The photomedical device comprises a light source part and a power supply part, wherein the light source part is electrically connected with the power supply part, and is characterized in that the light source part comprises a base cloth, a connecting layer, a light source layer and a covering layer, the connecting layer is laminated on the base cloth, the light source layer is laminated on the connecting layer, the covering layer is of a light-transmitting structure and is laminated on the light source layer, the light source layer and the connecting layer are covered, and the power supply part is used for lighting the light source layer.
2. The photomedical device of claim 1, wherein the power supply portion and the light source portion form an integrated structure therebetween, or the power supply portion and the light source portion are in an independent structure, and the power supply portion and the light source portion are electrically connected by a transmission line; the power supply part comprises a power supply part body and a power supply module arranged on the power supply part body, a controller is further arranged on the light source part or the power supply part, and the controller is respectively electrically connected with the power supply module and the light source layer and is used for adjusting the light-emitting wavelength, the time and the brightness of the light source layer.
3. The photomedical device of claim 1, wherein the light source portion further comprises a wireless power supply chip, and the power supply portion is wirelessly connected with the light source portion; the power supply part is an intelligent terminal, the light source part or the power supply part is also provided with a controller, and the controller is respectively electrically connected with the power supply part and the light source part and is used for adjusting the light-emitting wavelength, time and brightness of a light source layer in the light source part.
4. The photomedical device of claim 2 or 3, wherein a first temperature sensor for detecting the light emitting temperature of the light source layer is further arranged between the light source layer and the connecting layer, the first temperature sensor is respectively connected with the controller, and the controller is configured to receive and judge that the temperature signal detected by the first temperature sensor is higher than a temperature set value, and control the light source layer to cool down.
5. The photomedical device of claim 4, wherein the cover layer is provided with a sensor group, the sensor group comprising a second temperature sensor for detecting the temperature of the affected area to be phototherapy, a first sensor for detecting the body signal of the area to be phototherapy, and a second sensor for detecting the biochemical index signal of the area to be phototherapy; the second temperature sensor, the first sensor and the second sensor are respectively connected with the controller and the power supply part; the controller is used for formulating and/or changing the parameters of the medicine related to the light source layer or the affected part to be phototherapy according to the detection signals of the second temperature sensor, the first sensor and the second sensor.
6. The photomedical device of claim 1, wherein the covering layer is a fabric layer having a transmittance of greater than 1% for controlling the dose and temperature of light exiting the covering layer;
one or more of silver ions, silver nanowires, iodide ions, a photosensitizer and a drying agent are doped in the covering layer, and the side surface of the covering layer, which is attached to a part to be phototherapeutic, is of a concave-convex structure or an arched structure;
or the covering layer comprises a drug care layer and a sweat guide layer stacked on the outer side of the drug care layer, the drug care layer is stacked on the light source layer and is a packaging base material doped with one or more of silver ions, silver nanowires, iodide ions and a photosensitizer, a drying agent is arranged in the packaging base material, and a plurality of air holes communicated with the drying agent are formed in the packaging base material; the sweat guide layer is of a concave-convex structure or an arch structure.
7. The photomedical device of claim 6, wherein the light source further comprises an isolation layer laminated between the cover layer and the light source layer, wherein the isolation layer may have scattering particles disposed therein, wherein the isolation layer is an indium tin oxide coating or aerogel material, and wherein the scattering particles are made of TiO2Particles, ZrO2Particles, SiO2Particles, SiO particles, TiO particles.
8. The photomedical device of claim 5, further comprising a protective layer disposed on the cover layer, the protective layer being removable during use of the photomedical device.
9. The photomedical device of claim 2 or 3, wherein the light source layer comprises: the LED lamp comprises a flexible substrate and a plurality of LED lamp beads arranged on the flexible substrate;
or, the light source layer is a flexible OLED screen body; the controller controls the light emitting wavelength range of the light source layer to be 260 nm-1018 nm, preferably 260 nm-460 nm and 590 nm-810 nm; the irradiation power density of the light source layer is 1000mW/cm2Below, 1mW/cm is preferable2-100mW/cm2。
10. The photomedical device of claim 1, wherein the base fabric is provided at both ends with attachment structures I for fixing the light source portion to a site to be phototherapy; the power supply part is provided with a fitting structure II, so that wearing and power supply are facilitated.
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