CN111789802B - Anti-drop active agent, application and anti-drop composition containing same - Google Patents

Anti-drop active agent, application and anti-drop composition containing same Download PDF

Info

Publication number
CN111789802B
CN111789802B CN202010872957.0A CN202010872957A CN111789802B CN 111789802 B CN111789802 B CN 111789802B CN 202010872957 A CN202010872957 A CN 202010872957A CN 111789802 B CN111789802 B CN 111789802B
Authority
CN
China
Prior art keywords
drop
active agent
application
composition
hair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202010872957.0A
Other languages
Chinese (zh)
Other versions
CN111789802A (en
Inventor
张守华
高嘉阳
黄克文
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hard Core Pharmaceutical Technology Shanghai Co ltd
Original Assignee
Hard Core Pharmaceutical Technology Shanghai Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hard Core Pharmaceutical Technology Shanghai Co ltd filed Critical Hard Core Pharmaceutical Technology Shanghai Co ltd
Priority to CN202010872957.0A priority Critical patent/CN111789802B/en
Publication of CN111789802A publication Critical patent/CN111789802A/en
Application granted granted Critical
Publication of CN111789802B publication Critical patent/CN111789802B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Abstract

The application provides an anti-drop active agent, application and an anti-drop composition containing the same, and relates to the technical field of daily necessities. The anti-drop active agent comprises caffeine, extract of semen Caesalpiniae Oligocarpae, lysine and cysteine. The anti-drop composition is mainly prepared from the following raw materials in percentage by mass: 50-60% of surfactant, 1.3-4% of anti-drop active agent, 0.6-2% of emulsifier and the balance of solvent. The application has the advantages that the anti-drop active agent achieves higher anti-drop effect by blocking DHT generation, promoting hair follicle cell proliferation and providing nutrition support for cells, and the anti-drop composition prepared by the anti-drop active agent has good anti-drop effect, convenient use, easily available raw materials and convenient popularization.

Description

Anti-drop active agent, application and anti-drop composition containing same
Technical Field
The application relates to the technical field of daily necessities, in particular to an anti-drop active agent, application and an anti-drop composition containing the same.
Background
Alopecia is a problem that people cannot avoid in daily life, and is divided into physiological and pathological aspects. Physiological hair loss refers to normal hair loss, and new hair can be produced along with metabolism and time of a human body without excessive worry. However, pathological alopecia is abnormal or excessive hair loss, which occurs at a rate lower than that of new hair, and gradually causes the hair to be thin and finally forms baldness or even baldness. The alopecia is mainly androgenetic alopecia (also called seborrheic alopecia) caused by abnormal androgen metabolism, and accounts for more than 90%. Androgens produce Dihydrotestosterone (DHT) via 5 a-reductase, which causes a series of physiological and biochemical reactions by binding to intracellular androgen receptors, thereby miniaturizing the hair follicle progressively, tapering the growing period of hair, and shortening the hair growth cycle, as a result of which the originally dark hair gradually turns into pale vellus hair, which finally falls off as a result of the atrophy of the hair follicle, resulting in baldness of the forehead, crown area and top of the head.
At present, the routes for treating alopecia mainly comprise 3 routes: blocking DHT production, promoting follicular cell proliferation and nutritional support. The related treatment products in the current market have single treatment way, and can not improve alopecia in a whole way, so that the use mode of patients is complex, the treatment cost is high, the effect is good or bad, and the hair loss treatment device is not suitable for compliance of long-term use of users. With the continuous increase of social pressure and the acceleration of life rhythm, the continuous deterioration of environment and the eating habit of bad diet, the number of patients suffering from alopecia is increased, the demand for alopecia or preventing alopecia is higher, and no product has the effects of good hair growing effect, convenient use, easy raw material and convenient popularization.
Disclosure of Invention
The application aims to provide an anti-drop active agent, which can improve the route of alopecia by directly blocking the generation of DHT, promoting cell proliferation to counteract the influence of DHT, providing nutrition support for hair roots and the like, so as to achieve the purpose of preventing alopecia.
Another object of the present application is to provide the use of the aforementioned anti-release active agent for the preparation of an anti-release composition.
Another object of the present application is to provide an anti-slip composition containing the aforementioned anti-slip agent. The anti-drop composition is characterized by good anti-drop effect, convenient use, easily available raw materials and convenient popularization by reasonably compounding the anti-drop active agent and other hair base materials.
The application solves the technical problems by adopting the following technical scheme.
In one aspect, the embodiment of the application provides an anti-drop active agent, which comprises the following components in parts by weight: the weight ratio of the caffeine to the saw palmetto extract to the lysine to the cysteine is (1-2): 0.1-1): 0.1-0.5.
In another aspect, embodiments of the present application provide an application of the anti-drop active agent in preparing an anti-drop composition.
On the other hand, the embodiment of the application provides an anti-drop composition containing the anti-drop active agent, which is mainly prepared from the following raw materials in percentage by mass: 50-60% of surfactant, 1.3-4% of anti-drop active agent, 0.6-2% of emulsifying agent and the balance of solvent.
In summary, compared with the prior art, the embodiments of the present application have at least the following advantages or beneficial effects:
1. the anti-drop active substance provided by the application prevents alopecia by blocking DHT generation, promoting hair follicle cell proliferation and supporting nutrition in a whole way, specifically, the extract of the saw palmetto contains beta-sitosterol which is a natural analogue of androgens, and blocks the influence of DHT on hair follicles; caffeine can promote cell proliferation, and counteract the influence of DHT on hair follicle microminiaturization; cysteine and lysine can provide sufficient nutritional support to hair follicle cells to promote hair growth.
2. Compared with the existing anti-drop medicines, the anti-drop active agent provided by the application is different from the conventional anti-drop medicines, is not a medicine, does not increase the cellular metabolism burden, has small anaphylactic reaction and has no adverse reaction.
3. The anti-drop composition prepared by the anti-drop active agent provided by the application is in the form of shampoo, is a daily product, has high use frequency, keeps the anti-drop effect, and does not increase the living burden of a user after long-term use due to the daily product.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention. Furthermore, where noted, the terms "consisting essentially of" and "balance" in the claims of the present application are to be understood as including other substances as required in addition to those recited in the claims.
The embodiment of the application provides an anti-drop active agent which comprises caffeine, a saw palmetto extract, lysine and cysteine.
In some embodiments of the present application, the weight ratio of caffeine, saw palmetto extract, lysine and cysteine is (1-2): 0.1-1): 0.1-0.5.
In some embodiments of the present application, the anti-drop active agent comprises the following components in weight ratio: the weight ratio of the caffeine to the extract of the saw palmetto, the lysine to the cysteine is 1.2:0.5:0.3:0.3.
In another aspect, embodiments of the present application provide an application of the anti-drop active agent in preparing an anti-drop composition.
On the other hand, the embodiment of the application provides an anti-drop composition containing the anti-drop active agent, which is mainly prepared from the following raw materials in percentage by mass: 50-60% of surfactant, 1.3-4% of anti-drop active agent, 0.6-2% of emulsifying agent and the balance of solvent.
In some embodiments of the present application, the above-described anti-slip composition, the surfactant comprises the following components in weight percent: 25 to 35 percent of laureth sodium sulfate, 17 to 20 percent of cocamidopropyl betaine and 8 to 10 percent of cocoyl isethionate sodium.
In some embodiments of the present application, the anti-drop composition is mainly prepared from the following raw materials in percentage by mass: 60% of surfactant, 2% of anti-drop active agent, 2% of emulsifier and the balance of solvent.
In some embodiments of the present application, the anti-drop composition further comprises 4.5% -15.5% of a functional auxiliary agent.
In some embodiments of the present application, the above-described anti-slip composition, the functional auxiliary comprises the following components in weight percent: 1.7 to 5.7 percent of humectant, 0.6 to 2 percent of hair conditioning agent, 0.3 to 1.5 percent of antistatic agent, 0.1 to 0.5 percent of preservative, 0.1 to 0.5 percent of anti-inflammatory agent, 0.1 to 0.5 percent of skin conditioning agent, 0.5 to 1.5 percent of cooling agent, 0.5 to 1.5 percent of softener, 0.08 to 0.12 percent of thickening agent, 0.5 to 1.5 percent of viscosity agent and 0.08 to 0.12 percent of chelating agent.
In some embodiments of the present application, the above-described anti-slip composition, the humectant comprises the following components in weight percent: 0.5 to 1.5 percent of panthenol, 0.1 to 0.5 percent of sunflower seed oil unsaponifiable matter, 0.1 to 0.5 percent of octanediol, 0.3 to 0.7 percent of nicotinamide, 0.1 to 0.5 percent of tocopherol, 0.5 to 1.5 percent of 1, 3-propanediol and 0.1 to 0.5 percent of sunflower seed oil.
In some embodiments of the present application, the anti-drop composition is mainly prepared from the following raw materials in percentage by mass: sodium laureth sulfate 30%, cocamidopropyl betaine 20%, sodium cocoyl isethionate 10%, caffeine 1.5%, saw palmetto extract 0.8%, lysine 0.3%, cysteine 0.3%, octyldodecanol 0.3%, cocamide MEA1%, panthenol 1%, sunflower seed oil unsaponifiables 0.1%, octanediol 0.1%, nicotinamide 0.5%, tocopherol (vitamin E) 0.1%, 1, 3-propanediol 1%, sunflower seed oil 0.1%, hydrolyzed wheat protein PG-propylsilanetriol 1%, extract of Coprinus australis/leaves/rattan 0.3%, polyquaternium-70.3%, polyquaternium-10.3%, guar gum hydroxypropyl trimethyl ammonium chloride 0.3%, phenoxyethanol 0.3%, allantoin 0.3%, black tea seed oil 0.3%, menthol 1%, jojoba wax PEG-120 esters 1%, sodium sulfate 0.1%, sodium chloride 1% and disodium EDTA 0.1%.
The features and capabilities of the present application are described in further detail below in connection with the examples.
Example 1
The aim of this example is to provide an anti-release active agent.
The anti-drop active agent provided in this example can be added as an active ingredient to various anti-drop compositions. The anti-drop active agent comprises 1 to 2 percent of caffeine, a saw palmetto extract, and lysine and cysteine which are sequentially 1 to 2 percent, 0.1 to 1 percent, 0.1 to 0.5 percent and 0.1 to 0.5 percent by mass, and are sequentially preferably 1.2 percent, 0.5 percent, 0.3 percent and 0.3 percent by mass.
Example 2
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in table 1. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine and cysteine respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 1
Example 3
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in table 2. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine, cysteine and functional auxiliary agent respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 2
Example 4
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in Table 3. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine, cysteine and functional auxiliary agent respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 3 Table 3
Example 5
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in table 4. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine, cysteine and functional auxiliary agent respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 4 Table 4
Example 6
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in table 5. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine, cysteine and functional auxiliary agent respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 5
Example 7
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in Table 6. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine, cysteine and functional auxiliary agent respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 6
Example 8
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in table 7. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine, cysteine and functional auxiliary agent respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 7
Example 9
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in Table 8. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine, cysteine and functional auxiliary agent respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 8
Example 10
The object of this example is to provide an anti-slip composition.
The anti-drop composition provided by the application is prepared from the raw materials shown in Table 9. Uniformly mixing water, sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA, heating and stirring until sodium laureth sulfate, cocamidopropyl betaine, sodium cocoyl isethionate and cocamide MEA are dissolved to obtain a clear solution, cooling the solution to room temperature, and finally adding caffeine, saw palmetto extract, lysine, cysteine and functional auxiliary agent respectively in a stirring state, and uniformly stirring to obtain the anti-drop composition.
TABLE 9
/>
The long-term use experience of a plurality of users is recorded, the anti-hair-loss effect of the anti-hair-loss composition provided by the application can reach more than 95%, the hair growth rate can reach more than 90%, and the cost of long-term use of people is not much different from that of common shampoo, so that the anti-hair-loss shampoo is widely popularized.
Note that in examples 3 to 10, panthenol, sunflower seed oil unsaponifiable matter, octanediol, nicotinamide and tocopherol (vitamin E), 1, 3-propanediol and sunflower seed oil were used as moisturizers, ensuring the moisture of scalp and the moisture of hair surface after the use of the anti-hair composition; hydrolyzed wheat protein PG-propylsilanol and extract of herba Ardisiae Japonicae/leaf/vine are used as hair conditioner, and can increase stability of each effective component in the composition, and moisten hair to make hair easy to dry comb and smooth touch; the polyquaternium-7, guar hydroxypropyl trimethyl ammonium chloride and polyquaternium-10 are used as antistatic agents, so that the damage of static electricity to hair is reduced; meanwhile, allantoin is used as an anti-inflammatory agent, a release anti-sensitization agent, ribes nigrum seed oil skin is used as a skin conditioner, menthol is used as a cooling agent, and jojoba wax PEG-120 esters are used as softener, so that the overall use feeling of a user is improved; in addition, phenoxyethanol is used as a preservative, sodium sulfate is used as a thickening agent, sodium chloride is used as a viscosity agent to control the viscosity of the composition, and disodium EDTA is used as a chelating agent so as to improve the overall stability of the composition.
Meanwhile, in examples 2 to 10, citric acid can be used for adjusting the pH according to actual conditions, so that the anti-drop composition has better use feeling, and the citric acid can also be used as a exfoliating agent and an antibacterial agent to improve the overall performance of the product.
In addition, the anti-hair loss active agent provided by the application can be used for preparing anti-hair loss shampoo, anti-hair loss conditioner, shampoo and the like, and can also be used in other fields with anti-hair loss requirements. The anti-drop composition provided by the application is not limited to be used for seborrheic alopecia, and can be used as alopecia caused by other reasons or anti-alopecia products, namely can be applied to all anti-drop fields.
In summary, the anti-release active agent and the anti-release composition according to the embodiments of the present application have the following advantages:
1. the anti-alopecia active substance provided by the application can improve the route of alopecia by directly blocking the generation of DHT, promoting cell proliferation to counteract the influence of DHT, providing nutrition support for hair roots and the like, so as to achieve the purpose of preventing alopecia, specifically, the extract of the brown fruit of the saw blade contains beta-sitosterol which is a natural analogue of androgen, and blocks the influence of DHT on hair follicles; caffeine can promote cell proliferation, and counteract the influence of DHT on hair follicle microminiaturization; cysteine and lysine can provide sufficient nutritional support to hair follicle cells to promote hair growth.
2. Compared with the existing anti-drop medicines, the anti-drop active agent provided by the application is different from the conventional anti-drop medicines, is not a medicine, does not increase the cellular metabolism burden, has small anaphylactic reaction and has no adverse reaction.
3. The anti-drop composition prepared by the anti-drop active agent provided by the application is in the form of shampoo, is a daily product, has high use frequency, keeps the anti-drop effect, and does not increase the living burden of a user after long-term use due to the daily product.
The embodiments described above are some, but not all embodiments of the application. The detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.

Claims (1)

1. The anti-drop composition is characterized by being prepared from the following raw materials in percentage by mass: 25-35% of laureth sulfate sodium, 17-20% of cocoamidopropyl betaine, 8-10% of cocoyl isethionate sodium, 1.5% of caffeine, 0.8% of saw palmetto extract, 0.3% of lysine, 0.3% of cysteine, 0.3% of octyl dodecanol, 1% of cocoamidoMEA, 0.5-1.5% of panthenol, 0.1-0.5% of sunflower seed oil unsaponifiable matter, 0.1-0.5% of octanediol, 0.3-0.7% of nicotinamide, 0.1-0.5% of tocopherol, 0.5-1.5% of 1, 3-propanediol, 0.1-0.5% of sunflower seed oil, 1% of hydrolyzed wheat protein PG-propylsilanetriol, 0.3% of cepharanthine/leaf/rattan extract, 0.3% of polyquaternium-7.3%, 0.3% of polyquaternium-10.3% of guar gum hydroxypropyl trimethylammonium chloride, 0.3% of phenoxyethanol, 0.3% of PEG (PEG) seed oil, 0.3% of black tea seed oil, 1-1.5% of 1% of palmiton sodium chloride, and the balance sodium chloride, and 1.1% of sodium chloride.
CN202010872957.0A 2020-08-26 2020-08-26 Anti-drop active agent, application and anti-drop composition containing same Active CN111789802B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010872957.0A CN111789802B (en) 2020-08-26 2020-08-26 Anti-drop active agent, application and anti-drop composition containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010872957.0A CN111789802B (en) 2020-08-26 2020-08-26 Anti-drop active agent, application and anti-drop composition containing same

Publications (2)

Publication Number Publication Date
CN111789802A CN111789802A (en) 2020-10-20
CN111789802B true CN111789802B (en) 2023-10-24

Family

ID=72834037

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010872957.0A Active CN111789802B (en) 2020-08-26 2020-08-26 Anti-drop active agent, application and anti-drop composition containing same

Country Status (1)

Country Link
CN (1) CN111789802B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116712374B (en) * 2023-08-08 2023-10-31 广州善元堂健康科技股份有限公司 High-stability alopecia-preventing composition and preparation method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009053163A1 (en) * 2007-10-25 2009-04-30 Unilever Plc Hair care composition
KR100917673B1 (en) * 2007-12-06 2009-09-18 주식회사 솔레오 Composition for preventing alopecia or growing hair containing the cation/anion mixed surfactant comprising a caffein
CN110123684A (en) * 2018-02-09 2019-08-16 东莞自然衡健康科技有限公司 A kind of hair follicle former base tax liquid living and preparation method thereof with anticreep, hair regrowth
CN110403882A (en) * 2019-09-02 2019-11-05 佛山科学技术学院 A kind of shampoo with hair-growing and hair care effect

Also Published As

Publication number Publication date
CN111789802A (en) 2020-10-20

Similar Documents

Publication Publication Date Title
JP5096742B2 (en) Composition for scalp and hair
JP4974532B2 (en) Use of at least one cypress plant extract as an anti-glycation agent
CN110025658A (en) A kind of hair-loss preventing and hair-restoring liquid and preparation method thereof
CN108186385A (en) A kind of hair scalp cleaning compositions
CN110025519A (en) A kind of amino acid shampoo that moisturizing is releived
CN110123659A (en) A kind of Anti-hair loss composition and its in the application for preparing Anti-hair loss and washing in shield product
US5750107A (en) Hair growth promoter
CN107550795A (en) Nourish reparation, black hair anticreep camellia oleifera fruit shampoo and preparation method thereof
CN111789802B (en) Anti-drop active agent, application and anti-drop composition containing same
CN106798656B (en) Deep hair nourishing essence containing yak bone small molecule peptide and preparation method thereof
CN107921295A (en) Hair cleansing composition containing lotus flower oil and application thereof
CN102058513B (en) Chinese herbal medicine crude solution and cosmetic containing same
CN109350572A (en) A kind of cosmetic composition of Red blood streak dispelling and its preparation method and application
CN106937957B (en) Composition for treating androgenetic alopecia and shampoo thereof
EP1079795A2 (en) Preparation for treating human skin and human hair comprising a special active ingredient combination, and the use of this active ingredient combination
CN108721177A (en) Camellia amino acid shampoo
JP5219344B2 (en) Topical skin preparation
CN105380868A (en) Acne removal foundation make-up and preparation method thereof
KR102140185B1 (en) Hydrogel nanoparticles comprising hair growth solution of fermentation extract with natural products, method for manufacturing the same
KR20120051199A (en) Cosmetic compositions for hair or scalp to prevent hair loss and promote growing hair
KR100753437B1 (en) Nano-liposomal particles containing red ginseng irradiated with saponin, licorice, biotin, copper peptide, cytokine and cosmetics for hair care
JP2003089624A (en) Rinse for hair
CN101836941B (en) Microcapsule controlled-release anti-dandruff shampoo and preparation method thereof
CN115335069A (en) Composition for preventing alopecia and promoting hair growth containing extract of aerial parts of carrot
KR102131361B1 (en) Cosmetic composition for hair and scalp comprising keratin peptides as active ingredients

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information
CB02 Change of applicant information

Address after: Room A1355, Building 3, No. 112-118 Gaoyi Road, Baoshan District, Shanghai, 200000

Applicant after: Hard core Pharmaceutical Technology (Shanghai) Co.,Ltd.

Address before: 200120 Room 2145, Building 2, No. 495 Yuejin South Road, Xinhai Town, Chongming District, Shanghai (Guangming Rice Industry Economic Park)

Applicant before: Shanghai Yuanjing Information Technology Co.,Ltd.

GR01 Patent grant
GR01 Patent grant