CN111781380A - Heart-type fatty acid binding protein HFABP detection kit - Google Patents
Heart-type fatty acid binding protein HFABP detection kit Download PDFInfo
- Publication number
- CN111781380A CN111781380A CN202010716666.2A CN202010716666A CN111781380A CN 111781380 A CN111781380 A CN 111781380A CN 202010716666 A CN202010716666 A CN 202010716666A CN 111781380 A CN111781380 A CN 111781380A
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- heart
- hfabp
- fatty acid
- binding protein
- acid binding
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- 238000001514 detection method Methods 0.000 title claims abstract description 27
- 102100037738 Fatty acid-binding protein, heart Human genes 0.000 title claims description 12
- 101710136552 Fatty acid-binding protein, heart Proteins 0.000 title claims description 12
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 27
- 238000003466 welding Methods 0.000 claims description 9
- 238000001746 injection moulding Methods 0.000 claims description 6
- 244000309464 bull Species 0.000 claims description 4
- 102000030914 Fatty Acid-Binding Human genes 0.000 abstract description 3
- 108091022862 fatty acid binding Proteins 0.000 abstract description 3
- 238000006243 chemical reaction Methods 0.000 abstract description 2
- 238000003780 insertion Methods 0.000 description 17
- 230000037431 insertion Effects 0.000 description 17
- 230000000694 effects Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 238000004587 chromatography analysis Methods 0.000 description 2
- 230000001086 cytosolic effect Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000002633 protecting effect Effects 0.000 description 2
- 206010008479 Chest Pain Diseases 0.000 description 1
- 102000011026 Fatty Acid Binding Protein 3 Human genes 0.000 description 1
- 108010062715 Fatty Acid Binding Protein 3 Proteins 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 208000037906 ischaemic injury Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 230000036470 plasma concentration Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a heart-shaped fatty acid binding protein HFABP detection kit, which comprises a kit body, wherein the surface of the kit body is bonded with a shell, the rear side of the top of the shell is flexibly connected with a box cover, the bottom of the front side of the box cover is bonded with a fixed plate, the inner side of the fixed plate is rotatably connected with a rotating rod through a bearing, the rotating rod, a sleeve and the fixed plate are arranged to facilitate the rotating plate to drive an insert plate to rotate, the rotating plate is conveniently embedded into an insert slot through the insert slot, the outer surface of a sliding plate slides on the inner surface of the sliding slot through the through slot and the sliding slot, the sliding plate drives a limiting column to guide leftwards through the reaction force of a spring and also drives the insert rod to guide leftwards, so that the insert rod extends into the insert hole on the left side of a lock body, and through the arrangement, the detection kit has the advantage of, thereby facilitating the use of the detection reagent bottle.
Description
Technical Field
The invention relates to a detection kit, belongs to the technical field of detection kits, and particularly relates to a heart-type fatty acid binding protein HFABP detection kit.
Background
The heart-type fatty acid binding protein is a novel small cytoplasmic protein rich in heart, has high heart specificity, but also has low-concentration expression in tissues except the heart, can be found in blood 1-3 hours after the onset of chest pain after the occurrence of myocardial ischemic injury, reaches a peak value within 6-8 hours and returns to normal plasma level within 24-30 hours, the heart fatty acid binding cytoplasmic protein consists of 132 amino acids, is one of the most abundant proteins of the heart, the current clinical treatment detection mode is divided into chromatography detection and instrument detection modes, the detection modes comprise two modes, a chromatography detection method needs to use test paper or reagents, the current detection reagent bottle is packaged by using a detection kit, the current detection kit has the defect of poor protection effect in the taking process, and the reagent bottle is easy to drop and break, therefore, the use of a detection reagent bottle is inconvenient, and a heart-type fatty acid binding protein HFABP detection kit is provided for the purpose, so that the problems provided above are solved.
Disclosure of Invention
The invention aims to provide a heart-shaped fatty acid binding protein HFABP detection kit, which has the advantage of improving the protection effect of a detection reagent bottle and solves the problem of poor protection effect of the existing detection kit.
In order to achieve the purpose, the invention provides the following technical scheme: heart type fatty acid binding protein HFABP detect reagent box, comprises a box body, the surface bonding of box body has the casing, the soft lid that is connected with in rear side at casing top, the positive bottom of lid bonds and has the fixed plate, the inboard of fixed plate is rotated through the bearing and is connected with the bull stick, the sleeve has been cup jointed in the middle of the bull stick surface, the integrative injection moulding in sleeve surface has the rotor plate, the positive integrative injection moulding in top of rotor plate has the picture peg, the intermediate position at the positive top of casing bonds and has the lock body, the slot has been seted up in the left side of lock body inner chamber, logical groove has been seted up on the right side of lock body inner chamber, the spout has all been seted up to the upper and lower both sides that lead to the groove, the internal surface sliding connection of spout has the slide, the left side welding of slide has the inserted bar, the left side of inserted bar runs through, the outer surface of the limiting column is slidably sleeved with a spring, the left side of the spring is welded with the right side of the sliding plate, and the right side of the spring is welded with the joint of the inner cavity of the through groove.
Preferably, the inner cavity of the inserting plate is provided with a pin hole, and the inner surface of the pin hole is tightly attached to the outer surface of the inserting rod.
Preferably, the right side of lock body front and with lead to the corresponding position of groove and seted up the guide way, the welding of the front of slide has the pillar, the front of pillar runs through the guide way and extends to the welding of the front of lock body and has the shifting block.
Preferably, the left side of the inner cavity of the slot and the position matched with the inserted link for use are provided with jacks, and the inner surfaces of the jacks are tightly attached to the surface of the left side of the inserted link.
Preferably, the bottom fixedly connected with fixing base of lid, the fixed slot has been seted up to the bottom of fixing base, the quantity of fixed slot is six.
Preferably, the bottom of the inner cavity of the box body is embedded with a reagent bottle, and the top of the reagent bottle is tightly attached to the inner surface of the fixing groove.
Compared with the prior art, the invention has the following beneficial effects:
1. the rotary rod, the sleeve and the fixed plate are arranged, so that the rotary plate can drive the inserting plate to rotate conveniently, the inserting plate can be conveniently embedded into the inserting groove by arranging the inserting groove, the outer surface of the sliding plate can slide on the inner surface of the sliding groove conveniently by arranging the rotary rod, the sleeve and the fixed plate, the sliding plate can drive the limiting column to guide leftwards by the reaction force of the spring, and the inserting rod can be driven to guide leftwards by driving the inserting rod to extend into the inserting hole on the left side of the lock body.
2. The pin holes are formed, so that the insertion rods can be conveniently inserted into the pin holes, the insertion plates can be fixed, and the insertion plates are prevented from shaking;
through the arrangement of the guide groove, the shifting block is driven by the support column to slide left and right on the inner surface of the guide groove conveniently to guide the shifting block;
through the arrangement of the jacks, the insertion of the insertion rod is facilitated, the insertion rod is limited, and the insertion rod is prevented from displacement and falling off;
through setting up fixing base and fixed slot, made things convenient for the top of reagent bottle to fix, vibrations about avoiding appearing in the in-process of transport.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is an enlarged view of the structure of FIG. 1 at A in accordance with the present invention;
FIG. 3 is an enlarged view of the structure of FIG. 1 at B in accordance with the present invention;
FIG. 4 is a perspective view of the housing construction of the present invention;
FIG. 5 is a front view of the housing structure of the present invention;
fig. 6 is an enlarged view of the structure of fig. 5 at C according to the present invention.
In the figure: 1. a box body; 2. a housing; 3. a box cover; 4. a fixing plate; 5. a rotating rod; 6. a sleeve; 7. rotating the plate; 8. inserting plates; 9. a lock body; 10. a slot; 11. a through groove; 12. a chute; 13. a slide plate; 14. inserting a rod; 15. a limiting column; 16. a spring; 17. a pin hole; 18. a guide groove; 19. a pillar; 20. shifting blocks; 21. a jack; 22. a fixed seat; 23. fixing grooves; 24. and (4) reagent bottles.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Examples
Referring to fig. 1-6, a heart-shaped fatty acid binding protein HFABP detection kit comprises a box body 1, a shell 2 is bonded on the surface of the box body 1, a box cover 3 is flexibly connected on the rear side of the top of the shell 2, a fixing plate 4 is bonded on the bottom of the front of the box cover 3, a rotating rod 5 is rotatably connected on the inner side of the fixing plate 4 through a bearing, a sleeve 6 is sleeved in the middle of the outer surface of the rotating rod 5, a rotating plate 7 is integrally formed on the surface of the sleeve 6 by injection molding, an inserting plate 8 is integrally formed on the top of the front of the rotating plate 7 by injection molding, a lock body 9 is bonded in the middle of the top of the front of the shell 2, a slot 10 is formed on the left side of the inner cavity of the lock body 9, a through groove 11 is formed on the right side of the inner cavity of the lock body 9, sliding grooves 12 are formed on the upper and lower sides of, a limiting column 15 is welded on the right side of the sliding plate 13, a spring 16 is sleeved on the outer surface of the limiting column 15 in a sliding manner, the left side of the spring 16 is welded with the right side of the sliding plate 13, the right side of the spring 16 is welded with the joint of the inner cavity of the through groove 11, the rotating rod 5, the sleeve 6 and the fixing plate 4 are arranged, so that the rotating plate 7 can drive the inserting plate 8 to rotate conveniently, the inserting groove 10 is arranged, the rotating plate 7 can be conveniently embedded into the inserting groove 10, meanwhile, the through groove 11 and the sliding groove 12 facilitate the sliding of the outer surface of the sliding plate 13 on the inner surface of the sliding groove 12, the sliding plate 13 drives the limiting column 15 to guide leftwards through the counterforce of the spring 16, at the same time, the inserted link 14 is driven to be guided leftwards, so that the inserted link 14 extends into the insertion hole 21 at the left side of the lock body 9, through setting up above structure, possessed the advantage that improves detect reagent bottle protecting effect, solved the relatively poor problem of current detect reagent box protecting effect to make things convenient for detect reagent bottle's use.
Referring to fig. 2, the inner cavity of the insert plate 8 is provided with a pin hole 17, the inner surface of the pin hole 17 is tightly attached to the outer surface of the insert rod 14, and the insert rod 14 is conveniently inserted into the pin hole 17 through the pin hole 17 to fix the insert plate 8, so that the insert plate is prevented from shaking.
Referring to fig. 3 and 6, a guide groove 18 is formed in the right side of the front of the lock body 9 and in a position corresponding to the through groove 11, a support column 19 is welded to the front of the sliding plate 13, the front of the support column 19 penetrates through the guide groove 18 and extends to the front of the lock body 9, and a shifting block 20 is welded to the front of the lock body 9, so that the support column 19 drives the shifting block 20 to slide left and right on the inner surface of the guide groove 18 to guide the shifting block.
Referring to fig. 6, the insertion hole 21 is formed at the left side of the inner cavity of the slot 10 and at a position matched with the insertion rod 14 for use, the inner surface of the insertion hole 21 is tightly attached to the left surface of the insertion rod 14, and the insertion hole 21 is arranged to facilitate the insertion of the insertion rod 14, limit the insertion rod 14 and prevent the insertion rod from displacement and falling off.
Referring to fig. 1, a fixing seat 22 is fixedly connected to the bottom of the box cover 3, fixing grooves 23 are formed in the bottom of the fixing seat 22, the number of the fixing grooves 23 is six, the fixing seat 22 is made of hard sponge, and the fixing seat 22 and the fixing grooves 23 are arranged to facilitate fixing of the top of the reagent bottle 24 and avoid vertical vibration in the carrying process.
Referring to fig. 1, a reagent bottle 24 is embedded in the bottom of the inner cavity of the box body 1, and the top of the reagent bottle 24 is tightly attached to the inner surface of the fixing groove 23.
When the reagent bottle opener is used, a reagent bottle 24 is firstly embedded into an inner cavity of a box body 1, a box cover 3 is closed, the box cover 3 drives a fixing seat 22 to move downwards, so that the inner surface of a fixing groove 23 is tightly attached to the top of the reagent bottle 24, then a shifting block 20 is shifted rightwards, the shifting block 20 drives a sliding plate 13 to slide on the inner surface of a sliding groove 12 through a supporting column 19, meanwhile, a limiting column 15 is also driven to extrude a spring 16, the sliding plate 13 drives an inserting rod 14 to move rightwards, so that the inserting rod 14 is far away from an inserting hole 21, at the moment, a rotating rod 5 is rotated, the rotating rod 5 drives a sleeve 6 to rotate through a bearing, the sleeve 6 drives an inserting plate 8 to rotate through a rotating plate 7, so that the inserting plate 8 is inserted into the inner cavity of a slot 10, at the moment, the shifting block 20 is loosened, the limiting column 15 and the sliding plate 13 are ejected, make the inserted bar 14 run through lock body 9 to run through pinhole 17 and insert to the inner chamber of jack 21, and then fix lid 3 and casing 2, improved the safeguard effect, avoid reagent bottle 24 to appear rocking, thereby increase reagent bottle 24's broken risk, through setting up above structure, possessed the advantage that improves the protection effect of testing reagent bottle, solved the relatively poor problem of current testing kit safeguard effect, thereby made things convenient for the use of testing reagent bottle.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. Heart type fatty acid binding protein HFABP detect reagent box, including box body (1), its characterized in that: the surface bonding of box body (1) has casing (2), the rear side soft of casing (2) top is connected with lid (3), lid (3) positive bottom bonds and has fixed plate (4), the inboard of fixed plate (4) is rotated through the bearing and is connected with bull stick (5), sleeve (6) have been cup jointed to the centre department of bull stick (5) surface, the integrative injection moulding in surface of sleeve (6) has commentaries on classics board (7), the integrative injection moulding in positive top of commentaries on classics board (7) has picture peg (8), the intermediate position at casing (2) positive top bonds and has lock body (9), slot (10) have been seted up in the left side of lock body (9) inner chamber, logical groove (11) have been seted up on the right side of lock body (9) inner chamber, spout (12) have all been seted up to the upper and lower both sides that lead to groove (11), the internal surface sliding connection of spout (12) has slide, the left side welding of slide (13) has inserted bar (14), the left side of inserted bar (14) runs through lock body (9) and extends to the inner chamber that leads to groove (11), the right side welding of slide (13) has spacing post (15), the surface slip cover of spacing post (15) is equipped with spring (16), the left side of spring (16) and the right side welding of slide (13), the right side of spring (16) and the junction welding that leads to groove (11) inner chamber.
2. The heart-type fatty acid binding protein HFABP detection kit according to claim 1, characterized in that: the inner cavity of the inserting plate (8) is provided with a pin hole (17), and the inner surface of the pin hole (17) is tightly attached to the outer surface of the inserting rod (14).
3. The heart-type fatty acid binding protein HFABP detection kit according to claim 1, characterized in that: the right side of lock body (9) front and with lead to groove (11) corresponding position seted up guide way (18), the front welding of slide (13) has pillar (19), the front welding that the guide way (18) was run through and extend to lock body (9) of pillar (19) has shifting block (20).
4. The heart-type fatty acid binding protein HFABP detection kit according to claim 1, characterized in that: the left side of slot (10) inner chamber and with inserted bar (14) cooperation position of using seted up jack (21), the internal surface of jack (21) closely laminates with the left surface of inserted bar (14).
5. The heart-type fatty acid binding protein HFABP detection kit according to claim 1, characterized in that: the bottom fixedly connected with fixing base (22) of lid (3), fixed slot (23) have been seted up to the bottom of fixing base (22), the quantity of fixed slot (23) is six.
6. The heart-type fatty acid binding protein HFABP detection kit of claim 5, wherein: the bottom of the inner cavity of the box body (1) is embedded with a reagent bottle (24), and the top of the reagent bottle (24) is tightly attached to the inner surface of the fixing groove (23).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010716666.2A CN111781380A (en) | 2020-07-23 | 2020-07-23 | Heart-type fatty acid binding protein HFABP detection kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010716666.2A CN111781380A (en) | 2020-07-23 | 2020-07-23 | Heart-type fatty acid binding protein HFABP detection kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111781380A true CN111781380A (en) | 2020-10-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010716666.2A Pending CN111781380A (en) | 2020-07-23 | 2020-07-23 | Heart-type fatty acid binding protein HFABP detection kit |
Country Status (1)
| Country | Link |
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| CN (1) | CN111781380A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117360931A (en) * | 2023-12-07 | 2024-01-09 | 鹍远泰州医学检验实验室有限公司 | Tumor marker detection kit |
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| CN117360931B (en) * | 2023-12-07 | 2024-04-05 | 鹍远泰州医学检验实验室有限公司 | Tumor marker detection kit |
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Application publication date: 20201016 |
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