CN111773532A - Skin penetration promoting method for plastic and beauty - Google Patents
Skin penetration promoting method for plastic and beauty Download PDFInfo
- Publication number
- CN111773532A CN111773532A CN202010684187.7A CN202010684187A CN111773532A CN 111773532 A CN111773532 A CN 111773532A CN 202010684187 A CN202010684187 A CN 202010684187A CN 111773532 A CN111773532 A CN 111773532A
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- Prior art keywords
- ultrasonic
- beauty
- face
- worker
- ultrasonic wave
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0034—Skin treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0039—Ultrasound therapy using microbubbles
Abstract
The invention discloses a transdermal permeation promoting method for plastic cosmetology, which is characterized in that a worker uniformly applies a cosmetology liquid medicine on the face of the cosmetology worker to uniformly cover a layer of cosmetology liquid medicine on the face of the cosmetology worker, the worker sleeves ultrasonic probes of an ultrasonic permeation promoting instrument on the hand, ten ultrasonic probes are arranged and are respectively and electrically connected with a super-nerve generator on the ultrasonic permeation promoting instrument, each ultrasonic probe is fixed on a finger ring sleeve, the ten finger ring sleeves are respectively sleeved on ten fingers of two hands of the worker, the ultrasonic probes are positioned on the palm and face downwards, the hand of the worker presses the face of the cosmetology worker and simultaneously sends out ultrasonic permeation promotion through the ultrasonic probes, and the ultrasonic probes promote the permeation of the cosmetology liquid medicine on the face of the cosmetology worker. The invention has the advantages of large contact area and high efficiency because the hand of a worker rubs the face of a beauty worker and simultaneously emits ultrasonic waves to promote the permeation through the ultrasonic probe.
Description
Technical Field
The invention relates to the technical field of plastic cosmetology, in particular to a transdermal permeation promoting method for plastic cosmetology.
Background
The plastic cosmetology refers to medical science which has strong scientificity, technicality and artistry and aims at improving the external aesthetic feeling of a human body by repairing and remolding the appearance of the human body and the shapes of all parts of the human body by using operations, medicines, medical instruments and other medical technical methods. The popular way of shaping and beautifying is to carve the human body.
Orthopaedic surgery dates back hundreds of years, but rapid development is a matter of these years, and has developed very rapidly in recent years. There are many kinds of cosmetic products, and the cosmetic products can be separately understood. The therapeutic range of plastic surgery is mainly wounds, diseases, congenital or acquired tissue or organ defects and deformities, such as skin, muscle and bone. The treatment comprises two contents of repair and reconstruction. Surgical implantation of various autologous tissues, or repair of tissue defects or malformations due to various causes using xenogenic, xenogenic or tissue substitutes to improve or restore physiological function and appearance. Cosmetic is a product and method that alters the original bad behavior and disease (facial) to make it civilized, high-quality, with an acceptable appearance, with activities and procedures, or to do so.
For the absorption of the cosmetic liquid during beauty treatment, ultrasonic waves are often used to promote the absorption of the liquid medicine. The ultrasonic penetration promotion is also called ultrasonic medicine penetration therapy and sonophoresis therapy, which is to promote the percutaneous or mucosal absorption of medicines by utilizing ultrasonic waves. In the 60 s of the 20 th century, the technology is widely applied to sports medicine, and the clinical application of the technology is increasingly becoming a potential alternative to the traditional transdermal drug delivery after more than 40 years of research and the application of the ultrasound permeation-promoting technology is mature.
The general ultrasonic wave promotes that liquid medicine absorbs and adopts the ultrasonic wave to promote oozing appearance, and ultrasonic probe is the form of pen, and the staff makes a round trip to move pen-shaped ultrasonic probe on beauty personnel's face, and pen-shaped ultrasonic probe is limited with beauty personnel's face area of contact, needs to make a round trip certain, and efficiency is not high to pen-shaped ultrasonic probe has obvious sense of pressing on beauty personnel's face, is not convenient for use.
Disclosure of Invention
The invention aims to provide a percutaneous permeation promoting method for plastic cosmetology, which has the advantages of large contact area and high efficiency because the ultrasonic wave is sent out by an ultrasonic probe while the hand of a worker rubs the face of a cosmetology person, and solves the problems that the contact area between a pen-shaped ultrasonic probe and the face of the cosmetology person is limited, the pen-shaped ultrasonic probe needs to be fixed back and forth, the efficiency is not high, and the pen-shaped ultrasonic probe has obvious pressing feeling on the face of the cosmetology person and is inconvenient to use.
In order to achieve the purpose, the invention provides the following technical scheme: a skin penetration promoting method for shaping and beautifying features that the face of beautifying person is uniformly coated with a layer of liquid medicine, and the ultrasonic probe of ultrasonic wave promoting instrument is sleeved on hand of the face of beautifying person for promoting the penetration of said liquid medicine.
As a further scheme of the invention, ten ultrasonic probes are arranged, ten ultrasonic probes are respectively and electrically connected with a super-nerve wave generator on an ultrasonic wave permeation promoting instrument, each ultrasonic probe is fixed on a finger ring sleeve, the ten finger ring sleeves are respectively sleeved on ten fingers of two hands of a worker, the ultrasonic probes are positioned at the palm part and face downwards, and the hands of the worker press the face of the beauty worker and simultaneously emit ultrasonic wave permeation promoting through the ultrasonic probes.
As a further scheme of the invention, the ultrasonic wave has a cavitation effect, and the cavitation is that the activity of various forms of sound-induced bubbles is easy to generate a cavitation phenomenon in a liquid medium; in the negative phase, the bubbles increase to be close to their equilibrium radius, and in the positive phase, the pressure increase causes the radius of the bubbles to decrease, and the local temperature can rise to thousands of degrees centigrade once the bubbles implode; the increase and decrease of bubbles and the service life of the bubbles depend on the amplitude of parameter sound pressure of ultrasound, and the cavitation phenomenon of a liquid medium exists in two forms of a steady state and a transient state; the steady cavitation refers to bubbles which vibrate for a plurality of times around the equilibrium radius Rr, and the bubbles are subjected to a series of second-order phenomena in the vibration process, including radiation force and micro-acoustic flow, so that high velocity gradient and viscous stress exist at the surface of the vibration bubbles, and biological effect on cells and biological macromolecules at the surface can be generated, and living tissues are mainly the bubbles; the existence time of transient cavitation is very short, during the process, the cavitation core rapidly expands, and then suddenly contracts to collapse, implosion occurs to generate shock waves, and organisms such as cells in the cavitation center and the like are seriously damaged or even destroyed; cavitation occurs in and affects cells and tissues.
As a further aspect of the present invention, the mechanical effect is the most basic primary effect of the ultrasonic wave, and the vibration of the ultrasonic wave and the generated sound pressure have a direct influence on cells and tissues; the shearing force and the micro-acoustic flow generated by the ultrasonic wave can destroy cell membranes, the mechanical effect can widen the intercellular space, and the mechanical effect has the permeation promoting effect on increasing the permeability of the skin.
As a further scheme of the invention, the ultrasonic wave can generate radiation pressure, the medicament under the radiation pressure permeates the skin in a flowing mode, and the radiation pressure generated in the ultrasonic wave transmission process can promote the medicament to penetrate the skin and thrombus.
A skin penetration promoting method for plastic and cosmetic use comprises the following steps:
s1, after the face of the beauty staff is cleaned, the beauty staff lies on the beauty bed with the face of the beauty staff facing upwards;
s2, uniformly smearing the prepared beauty liquid medicine on the face of a beauty worker by a worker, scraping the liquid medicine on a scraper after the liquid medicine is smeared manually, scraping the redundant liquid medicine, and leaving a thin layer on the face of the beauty worker;
s3, respectively sleeving finger rings connected with ten ultrasonic probes on ten fingers of two hands by a worker, enabling the ultrasonic probes to be positioned downwards at the palms, starting an ultrasonic wave permeation promoting instrument, and enabling the ten ultrasonic probes to emit ultrasonic waves;
s4, the worker places the started ultrasonic probe on the face of the beauty staff, and the hand of the worker rubs the face of the beauty staff and sends ultrasonic waves to promote the penetration through the ultrasonic probe, so that the face of the beauty staff can better absorb the beauty liquid medicine;
and S5, after the cosmetic treatment course is finished, the staff closes the ultrasonic wave permeation promoting instrument, takes down the finger ring sleeve connected with the ultrasonic probe, and then cleans the ultrasonic probe and cleans the face of the cosmetic staff.
Compared with the prior art, the invention has the following beneficial effects: ten ultrasonic probes are respectively and electrically connected with a super-god wave generator on the ultrasonic wave permeation promoting instrument, each ultrasonic probe is fixed on a finger ring sleeve, the ten finger ring sleeves are respectively sleeved on ten fingers of two hands of a worker, and the ultrasonic probes are positioned at the palm downwards.
Starting the ultrasonic wave and promoting the instrument that oozes, ten ultrasonic transducer all send the ultrasonic wave, and the staff will start the ultrasonic transducer after the back place in beauty personnel's face, send the ultrasonic wave through ultrasonic transducer and promote the infiltration when staff's hand is according to rubbing beauty personnel's face, and area of contact is big, and is efficient, makes the cosmetic liquid medicine of absorption that beauty personnel's face can be better.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front", "rear", "both ends", "one end", "the other end", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be configured in a specific orientation, and operate, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "connected," and the like are to be construed broadly, such as "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example 1
The embodiment provided by the invention comprises the following steps: the utility model provides a cosmetic method of oozing is promoted with penetrating skin, the staff evenly coats cosmetic liquid medicine on beauty staff's face, make the even cosmetic liquid medicine of one deck that covers on beauty staff's face, the staff promotes the ultrasonic transducer cover of oozing the instrument with the ultrasonic wave on hand, ultrasonic transducer is provided with ten, ten ultrasonic transducer are connected with the ultrasonic wave generator electricity on promoting the instrument of oozing respectively, every ultrasonic transducer all fixes on the ring cover, ten ring covers overlap respectively on ten fingers of staff both hands, ultrasonic transducer is located palm department downwards, send ultrasonic wave through ultrasonic transducer and promote to ooze when staff's hand is according to rubbing cosmetic staff's face, promote to ooze through the cosmetic liquid medicine on beauty staff's face through ultrasonic transducer.
Example 2
The embodiment provided by the invention comprises the following steps: a skin penetration promoting method for shaping and beautifying features that ultrasonic waves have cavitation action, which is the cavitation phenomenon easily generated by the activity of sound-induced bubbles in liquid medium; in the negative phase, the bubbles increase to be close to their equilibrium radius, and in the positive phase, the pressure increase causes the radius of the bubbles to decrease, and the local temperature can rise to thousands of degrees centigrade once the bubbles implode; the increase and decrease of bubbles and the service life of the bubbles depend on the amplitude of parameter sound pressure of ultrasound, and the cavitation phenomenon of a liquid medium exists in two forms of a steady state and a transient state; the steady cavitation refers to bubbles which vibrate for a plurality of times around the equilibrium radius Rr, and the bubbles are subjected to a series of second-order phenomena in the vibration process, including radiation force and micro-acoustic flow, so that high velocity gradient and viscous stress exist at the surface of the vibration bubbles, and biological effect on cells and biological macromolecules at the surface can be generated, and living tissues are mainly the bubbles; the existence time of transient cavitation is very short, during the process, the cavitation core rapidly expands, and then suddenly contracts to collapse, implosion occurs to generate shock waves, and organisms such as cells in the cavitation center and the like are seriously damaged or even destroyed; cavitation occurs in and affects cells and tissues.
The cavitation plays an important role in increasing the permeability of the skin, can destroy lipid bilayers of the stratum corneum, change the structure of the stratum corneum, increase the intercellular space of the stratum corneum and form a water passage between the corneocytes so as to increase the permeability of the skin, and is a key mechanism of low-frequency ultrasonic penetration promotion. The selective inhibition of cavitation by using a coupling medium with high viscosity finds that the cavitation on the surface of the skin plays a key role in the increase of skin permeability caused by the low-frequency ultrasonic bow, and mainly plays a role in transient cavitation.
Example 3
The embodiment provided by the invention comprises the following steps: a skin penetration promoting method for plastic and cosmetic use, the mechanical effect is the most basic primary effect of ultrasonic wave, the vibration of ultrasonic wave and acoustic pressure produced have direct influence on cell and tissue; the shearing force and the micro-acoustic flow generated by the ultrasonic wave can destroy cell membranes, the mechanical effect can widen the intercellular space, and the mechanical effect has the permeation promoting effect on increasing the permeability of the skin.
Example 4
The embodiment provided by the invention comprises the following steps: a percutaneous permeation promoting method for shaping and beautifying features that ultrasonic waves generate radiation pressure, the medicine under the radiation pressure permeates through skin in flowing mode, and the radiation pressure generated by ultrasonic waves in the process of transmission can promote the medicine to penetrate through skin and thrombus.
Example 5
The embodiment provided by the invention comprises the following steps: a skin penetration promoting method for plastic and cosmetic use comprises the following steps:
s1, after the face of the beauty staff is cleaned, the beauty staff lies on the beauty bed with the face of the beauty staff facing upwards;
s2, uniformly smearing the prepared beauty liquid medicine on the face of a beauty worker by a worker, scraping the liquid medicine on a scraper after the liquid medicine is smeared manually, scraping the redundant liquid medicine, and leaving a thin layer on the face of the beauty worker;
s3, respectively sleeving finger rings connected with ten ultrasonic probes on ten fingers of two hands by a worker, enabling the ultrasonic probes to be positioned downwards at the palms, starting an ultrasonic wave permeation promoting instrument, and enabling the ten ultrasonic probes to emit ultrasonic waves;
s4, the worker places the started ultrasonic probe on the face of the beauty staff, and the hand of the worker rubs the face of the beauty staff and sends ultrasonic waves to promote the penetration through the ultrasonic probe, so that the face of the beauty staff can better absorb the beauty liquid medicine;
and S5, after the cosmetic treatment course is finished, the staff closes the ultrasonic wave permeation promoting instrument, takes down the finger ring sleeve connected with the ultrasonic probe, and then cleans the ultrasonic probe and cleans the face of the cosmetic staff.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Claims (6)
1. A skin penetration promoting method for plastic cosmetology is characterized in that: the working personnel evenly apply the beauty liquid medicine on the face of the beauty personnel to enable the face of the beauty personnel to be evenly covered with a layer of beauty liquid medicine, the working personnel sleeve the ultrasonic probe of the ultrasonic wave permeation promoting instrument on the hand, and the ultrasonic probe promotes the permeation of the beauty liquid medicine on the face of the beauty personnel.
2. The percutaneous penetration promoting method for plastic cosmetics according to claim 1, wherein: the ultrasonic wave probe is provided with ten, and ten ultrasonic wave probes are connected with ultrasonic wave generator electricity on the short oozing instrument of ultrasonic wave respectively, and every ultrasonic wave probe all fixes on the ring cover, and ten ring covers overlap respectively on ten fingers of staff two hands, and ultrasonic wave probe is located palm department and faces downwards, and the staff's hand is pressed and is sent ultrasonic wave through ultrasonic wave probe and promote oozing when cosmetic staff's face.
3. The percutaneous penetration promoting method for plastic cosmetics according to claim 1, wherein: the ultrasonic wave has a cavitation effect, and the cavitation is that the activity of various forms of sound-induced bubbles easily generates a cavitation phenomenon in a liquid medium; in the negative phase, the bubbles increase to be close to their equilibrium radius, and in the positive phase, the pressure increase causes the radius of the bubbles to decrease, and the local temperature can rise to thousands of degrees centigrade once the bubbles implode; the increase and decrease of bubbles and the service life of the bubbles depend on the amplitude of parameter sound pressure of ultrasound, and the cavitation phenomenon of a liquid medium exists in two forms of a steady state and a transient state; the steady cavitation refers to bubbles which vibrate for a plurality of times around the equilibrium radius Rr, and the bubbles are subjected to a series of second-order phenomena in the vibration process, including radiation force and micro-acoustic flow, so that high velocity gradient and viscous stress exist at the surface of the vibration bubbles, and biological effect on cells and biological macromolecules at the surface can be generated, and living tissues are mainly the bubbles; the existence time of transient cavitation is very short, during the process, the cavitation core rapidly expands, and then suddenly contracts to collapse, implosion occurs to generate shock waves, and organisms such as cells in the cavitation center and the like are seriously damaged or even destroyed; cavitation occurs in and affects cells and tissues.
4. The percutaneous penetration promoting method for plastic cosmetics according to claim 1, wherein: the mechanical effect is the most basic primary effect of the ultrasonic wave, and the vibration of the ultrasonic wave and the generated sound pressure have direct influence on cells and tissues; the shearing force and the micro-acoustic flow generated by the ultrasonic wave can destroy cell membranes, the mechanical effect can widen the intercellular space, and the mechanical effect has the permeation promoting effect on increasing the permeability of the skin.
5. The percutaneous penetration promoting method for plastic cosmetics according to claim 1, wherein: the ultrasonic wave can generate radiation pressure, the medicament under the radiation pressure permeates the skin in a flowing mode, and the radiation pressure generated in the ultrasonic wave transmission process can promote the medicament to penetrate the skin and thrombus.
6. The percutaneous penetration promoting method for plastic cosmetics according to claim 1, wherein: the use steps are as follows:
s1, after the face of the beauty staff is cleaned, the beauty staff lies on the beauty bed with the face of the beauty staff facing upwards;
s2, uniformly smearing the prepared beauty liquid medicine on the face of a beauty worker by a worker, scraping the liquid medicine on a scraper after the liquid medicine is smeared manually, scraping the redundant liquid medicine, and leaving a thin layer on the face of the beauty worker;
s3, respectively sleeving finger rings connected with ten ultrasonic probes on ten fingers of two hands by a worker, enabling the ultrasonic probes to be positioned downwards at the palms, starting an ultrasonic wave permeation promoting instrument, and enabling the ten ultrasonic probes to emit ultrasonic waves;
s4, the worker places the started ultrasonic probe on the face of the beauty staff, and the hand of the worker rubs the face of the beauty staff and sends ultrasonic waves to promote the penetration through the ultrasonic probe, so that the face of the beauty staff can better absorb the beauty liquid medicine;
and S5, after the cosmetic treatment course is finished, the staff closes the ultrasonic wave permeation promoting instrument, takes down the finger ring sleeve connected with the ultrasonic probe, and then cleans the ultrasonic probe and cleans the face of the cosmetic staff.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010684187.7A CN111773532A (en) | 2020-07-16 | 2020-07-16 | Skin penetration promoting method for plastic and beauty |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010684187.7A CN111773532A (en) | 2020-07-16 | 2020-07-16 | Skin penetration promoting method for plastic and beauty |
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| CN111773532A true CN111773532A (en) | 2020-10-16 |
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| CN202010684187.7A Pending CN111773532A (en) | 2020-07-16 | 2020-07-16 | Skin penetration promoting method for plastic and beauty |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102755692A (en) * | 2012-07-30 | 2012-10-31 | 王路 | Ultrasonic wave and ion conduction transdermal medicament or cosmetic conduction device |
| CN105944246A (en) * | 2016-06-01 | 2016-09-21 | 华南理工大学 | Cosmetic health preserving ultrasonic focusing massage rod |
| WO2017079758A1 (en) * | 2015-11-06 | 2017-05-11 | Bkr Ip Holdco Llc | Modified transdermal delivery device or patch and method of delivering insulin from said modified transdermal delivery device |
| CN109806513A (en) * | 2019-03-27 | 2019-05-28 | 广州市圣洁美美容科技有限公司 | A kind of cold and hot supersonic face care instrument |
-
2020
- 2020-07-16 CN CN202010684187.7A patent/CN111773532A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102755692A (en) * | 2012-07-30 | 2012-10-31 | 王路 | Ultrasonic wave and ion conduction transdermal medicament or cosmetic conduction device |
| WO2017079758A1 (en) * | 2015-11-06 | 2017-05-11 | Bkr Ip Holdco Llc | Modified transdermal delivery device or patch and method of delivering insulin from said modified transdermal delivery device |
| US20180325835A1 (en) * | 2015-11-06 | 2018-11-15 | Bkr Ip Holdco Llc | Modified transdermal delivery patch with multiple absorbent pads |
| CN105944246A (en) * | 2016-06-01 | 2016-09-21 | 华南理工大学 | Cosmetic health preserving ultrasonic focusing massage rod |
| CN109806513A (en) * | 2019-03-27 | 2019-05-28 | 广州市圣洁美美容科技有限公司 | A kind of cold and hot supersonic face care instrument |
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Application publication date: 20201016 |