CN111773158A

CN111773158A - Internal heat-reducing halitosis-removing whitening toothpaste and preparation method thereof

Info

Publication number: CN111773158A
Application number: CN202010785983.XA
Authority: CN
Inventors: 何炳梁
Original assignee: Guangzhou Mingli Daily Chemical Co ltd
Current assignee: Guangzhou Mingli Daily Chemical Co ltd
Priority date: 2020-08-07
Filing date: 2020-08-07
Publication date: 2020-10-16

Abstract

The invention discloses a fire-reducing halitosis-removing whitening toothpaste, which belongs to the technical field of toothpaste processing and is specifically prepared from the following substances: humectant, adhesive, sweetener, corrosion inhibitor, abrasive, foaming agent, essence, preservative, performance additive A, performance additive B and water. The toothpaste has the advantages of strong and stable efficacies of reducing internal heat, detoxifying, whitening and removing halitosis, good comprehensive characteristics, simple preparation method, easy popularization and application and good economic benefit.

Description

Internal heat-reducing halitosis-removing whitening toothpaste and preparation method thereof

Technical Field

The invention belongs to the technical field of toothpaste processing, and particularly relates to a fire-reducing halitosis-removing whitening toothpaste and a preparation method thereof.

Background

"people eat as the day, eat as the first with the teeth", the health state of the oral cavity is a mirror reflecting the quality of life and health. Nowadays, people pay more and more attention to oral health, and halitosis becomes a serious problem which troubles the life of people. The halitosis brings great troubles to the spirit and life of people, is particularly embarrassing in social interaction, and even causes social automutism due to long-term halitosis. The causes of halitosis are very complex, and statistics show that 80-90% of halitosis comes from oral cavity, and because the surface area of the back of the tongue is large, and the tongue has many papillae, fissure and depression, which are beneficial for the retention of bacteria, oral mucosa desquamation epithelium, food residues and the like, and serve as 'bacteria storage chamber', which causes halitosis. It has been found in many studies that the main components of bad breath odor are volatile sulfides, 90% of which are hydrogen sulfide and methyl mercaptan, and thus, it is necessary to remove bad breath in order to freshen breath.

Toothpaste and toothbrush are daily necessities for cleaning teeth and protecting oral hygiene. Usually, people need to use the toothbrush toothpaste in the morning and at night every day, and the toothbrush toothpaste can not only clean and protect teeth, but also directly improve the oral environment. The conventional toothpaste can clean the oral cavity to a certain extent and improve the breath, but the effect of removing the halitosis is not obvious, and particularly the long-acting inhibition of the halitosis cannot be realized.

The color and luster of the teeth also have great influence on the social contact of people, and a bright and white tooth brings great confidence to people and is beneficial to social contact. At present, toothpaste products for whitening teeth exist in the market, but the problems of limited whitening capability, common effect in long-term use and the like exist mostly.

In addition, with the better life of people at present, the food types eaten every day are more and more, the spicy food is deeply loved by most people, but the problem of the gingival swelling and pain caused by excessive internal heat due to hot air after eating is easily solved, and the toothpaste on the market cannot meet the requirements of cleaning and nursing.

The application numbers are: 201811265889.0 discloses a fire-reducing halitosis-removing whitening toothpaste, which comprises the following components in parts by weight: 2-6 parts of massecuite, 1-5 parts of reed rhizome, 1-2 parts of sodium dihydrogen pyrophosphate, 1 part of rosemary, 2-8 parts of sodium carboxymethylcellulose, 1-5 parts of sodium lauryl sulfate, 10-25 parts of glycerol, 35-45 parts of calcium phosphate, 1-5 parts of polyethylene glycol and 20-30 parts of purified water. Although the effect of reducing pathogenic fire and removing halitosis is achieved, the improvement and progress space is still large; in addition, the problem of poor comprehensive use quality still exists.

Disclosure of Invention

The invention aims to provide a fire-reducing halitosis-removing whitening toothpaste and a preparation method thereof.

The technical purpose of the invention is realized by the following technical scheme:

the internal heat-reducing halitosis-removing whitening toothpaste is prepared from the following substances in parts by weight:

40-55 parts of humectant, 1-1.5 parts of adhesive, 0.1-0.3 part of sweetening agent, 0.1-0.2 part of corrosion inhibitor, 25-30 parts of friction agent, 1.5-2 parts of foaming agent, 0.5-1 part of essence, 0.05-0.08 part of preservative, 0.3-0.5 part of performance additive A, 1-3 parts of performance additive B and 5-9 parts of water.

Preferably, the food is prepared from the following substances in parts by weight:

45-50 parts of humectant, 1.2-1.4 parts of adhesive, 0.15-0.25 part of sweetening agent, 0.15-0.18 part of corrosion inhibitor, 26-28 parts of friction agent, 1.7-1.9 parts of foaming agent, 0.6-0.8 part of essence, 0.06-0.07 part of preservative, 0.35-0.45 part of performance additive A, 1.5-2.5 parts of performance additive B and 6-8 parts of water.

More preferably, the food additive is prepared from the following substances in parts by weight:

48 parts of humectant, 1.3 parts of adhesive, 0.2 part of sweetening agent, 0.17 part of corrosion inhibitor, 27 parts of abrasive, 1.8 parts of foaming agent, 0.7 part of essence, 0.065 part of preservative, 0.4 part of performance additive A, 2 parts of performance additive B and 7 parts of water.

Further, the humectant is glycerin or sorbitol; the adhesive is sodium carboxymethyl cellulose; the sweetening agent is saccharin sodium; the corrosion inhibitor is sodium nitrate; the friction agent is calcite or aluminum hydroxide; the foaming agent is sodium lauryl sulfate; the preservative is sodium benzoate.

Further, the preparation method of the performance additive A comprises the following steps:

1) crushing noni fruits, putting into an extracting solution, performing ultrasonic extraction treatment for 5-8 hours, and performing suction filtration to obtain a suction filtration solution for later use;

2) carrying out high-speed centrifugation treatment on the suction filtration liquid obtained in the step 1), and removing centrifugal precipitates to obtain a centrifugal liquid for later use; controlling the rotation speed of the centrifugation to be 6800-7200 rpm;

3) filtering the centrifugate obtained in the step 2) to obtain filtrate for later use; the aperture of the filter membrane adopted during the filtration treatment is 6-10 μm;

4) freezing and drying the filtrate obtained in the step 3) to obtain the performance additive A.

Further, the extracting solution in the step 1) is composed of the following substances in parts by weight: 3-5 parts of sodium pyrophosphate, 2-6 parts of algal polysaccharide and 80-85 parts of edible alcohol; the concentration of the edible alcohol is 60%; and the frequency of the ultrasonic wave is controlled to be 520-580 kHz during ultrasonic leaching treatment.

Further, the freezing temperature in the freeze drying treatment in the step 4) is-10 to-15 ℃.

Further, the preparation method of the performance additive B comprises the following steps:

a. the method comprises the following steps of firstly, mixing mint leaves, dried orange peel, asiatic moonseed rhizome, tree peony bark, honeysuckle, grape seeds and water according to a weight ratio of 20-25: 4-7: 2-4: 5-9: 8-12: 3-6: 260-280, heating, boiling for 2-2.5 hours, and filtering to obtain filtrate for later use;

b. and c, heating and concentrating the filtrate obtained in the step a to 8-10% of the original volume.

A preparation method of toothpaste for reducing internal heat, removing halitosis and whitening comprises the following steps:

(1) weighing the following components in parts by weight: humectant, adhesive, sweetener, corrosion inhibitor, abrasive, foaming agent, essence, preservative, performance additive A, performance additive B and water;

(2) mixing the humectant, the adhesive, the sweetener, the corrosion inhibitor, the friction agent, the foaming agent, the essence and the preservative weighed in the step (1) together, and stirring uniformly;

(3) and (2) adding the performance additive A, the performance additive B and water weighed in the step (1) together, stirring uniformly again, and standing for 6-8 hours.

Compared with the prior art, the invention has the following advantages:

the invention provides a novel toothpaste for reducing internal heat, removing halitosis and whitening, which is characterized in that a plurality of raw material components are reasonably matched, the use quality of the toothpaste is effectively improved, particularly, two components of a performance additive A and a performance additive B are added and used, the two components well cooperate to improve the use performance of the toothpaste, wherein the performance additive A is a substance extracted from noni fruits, and the substance is rich in ingredients such as siloenin, antioxidant and antibacterial agents and is easy to be absorbed by oral cavity and gum, so that the development and repair of dental nerves are facilitated, the aging of the dental nerves and the like is delayed, the whiteness and color of teeth are endogenously enhanced, and the quality of the teeth is improved; the performance additive B is extracted from various Chinese herbal medicines, not only has good effects of oxidation resistance and the like, but also has effects of antibiosis, disinfection, fire clearing and the like, can obviously improve the effects of removing halitosis, reducing fire and expelling toxin, can promote the effects of enhancing the performance additive A on endogenous whitening and brightening of teeth, and has good synergistic effect; the toothpaste has strong and stable efficacies of reducing internal heat, detoxifying, whitening and removing halitosis and has good comprehensive characteristics when being used together with the addition of other components. The preparation method is simple, easy to popularize and apply, good in economic benefit, strong in competitiveness of the prepared toothpaste and extremely high in market competitiveness.

Detailed Description

Example 1

ingredients of raw materials	Parts by weight (parts)
		Moisture-retaining agent	40
Adhesive agent	1
		Sweetening agent	0.1
Corrosion inhibitor	0.1
		Friction agent	25
Foaming agent	1.5
		Essence	0.5
Preservative	0.05
		Performance additives A	0.3
Performance additives B	1
		Water (W)	5

The humectant is glycerin; the adhesive is sodium carboxymethyl cellulose; the sweetening agent is saccharin sodium; the corrosion inhibitor is sodium nitrate; the friction agent is calcite; the foaming agent is sodium lauryl sulfate; the preservative is sodium benzoate.

The preparation method of the performance additive A comprises the following steps:

1) crushing noni fruits, putting into the extracting solution, carrying out ultrasonic leaching treatment for 5 hours, and then carrying out suction filtration to obtain a suction filtration solution for later use;

2) carrying out high-speed centrifugation treatment on the suction filtration liquid obtained in the step 1), and removing centrifugal precipitates to obtain a centrifugal liquid for later use; controlling the rotating speed of the centrifugation to be 6800 rpm;

The extracting solution in the step 1) is composed of the following substances in parts by weight: 3 parts of sodium pyrophosphate, 2 parts of algal polysaccharide and 80 parts of edible alcohol; the concentration of the edible alcohol is 60%; the ultrasonic frequency is controlled to be 520kHz during the ultrasonic leaching treatment.

The freezing temperature in the freeze-drying treatment in the step 4) is-10 ℃.

The preparation method of the performance additive B comprises the following steps:

a. mint leaves, dried orange peel, asiatic moonseed rhizome, tree peony bark, honeysuckle, grape seeds and water are mixed according to the weight ratio of 20: 4: 2:5:8:3: 260, then heating and boiling for 2 hours, and filtering to obtain filtrate for later use;

b. and c, heating and concentrating the filtrate obtained in the step a to 8% of the original volume.

(3) and (2) adding the performance additive A, the performance additive B and water weighed in the step (1) together, stirring uniformly again, and standing for 6 hours.

Example 2

ingredients of raw materials	Parts by weight (parts)
		Moisture-retaining agent	45
Adhesive agent	1.2
		Sweetening agent	0.15
Corrosion inhibitor	0.15
		Friction agent	26
Foaming agent	1.7
		Essence	0.6
Preservative	0.06
		Performance additives A	0.35
Performance additives B	1.5
		Water (W)	6

Example 3

ingredients of raw materials	Parts by weight (parts)
		Moisture-retaining agent	48
Adhesive agent	1.3
		Sweetening agent	0.2
Corrosion inhibitor	0.17
		Friction agent	27
Foaming agent	1.8
		Essence	0.7
Preservative	0.065
		Performance additives A	0.4
Performance additives B	2
		Water (W)	7

The humectant is sorbitol; the adhesive is sodium carboxymethyl cellulose; the sweetening agent is saccharin sodium; the corrosion inhibitor is sodium nitrate; the friction agent is aluminum hydroxide; the foaming agent is sodium lauryl sulfate; the preservative is sodium benzoate.

1) crushing noni fruits, putting into the extracting solution, performing ultrasonic extraction treatment for 7 hours, and performing suction filtration to obtain a suction filtration solution for later use;

2) carrying out high-speed centrifugation treatment on the suction filtration liquid obtained in the step 1), and removing centrifugal precipitates to obtain a centrifugal liquid for later use; controlling the rotation speed of the centrifugation to 7000 rpm;

The extracting solution in the step 1) is composed of the following substances in parts by weight: 4 parts of sodium pyrophosphate, 4 parts of algal polysaccharide and 83 parts of edible alcohol; the concentration of the edible alcohol is 60%; and the ultrasonic frequency is controlled to be 550kHz during the ultrasonic leaching treatment.

The freezing temperature in the freeze-drying treatment in the step 4) is-13 ℃.

a. mint leaves, dried orange peel, asiatic moonseed rhizome, tree peony bark, honeysuckle, grape seeds and water are mixed according to the weight ratio of 22: 6: 3:8:10:5: 270, then heating and boiling for 2.3 hours, and filtering to obtain filtrate for later use;

b. and c, heating and concentrating the filtrate obtained in the step a to 9% of the original volume.

(3) and (2) adding the performance additive A, the performance additive B and water weighed in the step (1) together, stirring uniformly again, and standing for 7 hours.

Example 4

ingredients of raw materials	Parts by weight (parts)
		Moisture-retaining agent	50
Adhesive agent	1.4
		Sweetening agent	0.25
Corrosion inhibitor	0.18
		Friction agent	28
Foaming agent	1.9
		Essence	0.8
Preservative	0.07
		Performance additives A	0.45
Performance additives B	2.5
		Water (W)	8

1) crushing noni fruits, putting into the extracting solution, performing ultrasonic extraction treatment for 8 hours, and performing suction filtration to obtain a suction filtration solution for later use;

2) carrying out high-speed centrifugation treatment on the suction filtration liquid obtained in the step 1), and removing centrifugal precipitates to obtain a centrifugal liquid for later use; controlling the rotation speed of the centrifugation to be 7200 rpm;

The extracting solution in the step 1) is composed of the following substances in parts by weight: 5 parts of sodium pyrophosphate, 6 parts of algal polysaccharide and 85 parts of edible alcohol; the concentration of the edible alcohol is 60%; the ultrasonic frequency is controlled to be 580kHz during the ultrasonic leaching treatment.

The freezing temperature in the freeze-drying treatment in the step 4) is-15 ℃.

a. mint leaves, dried orange peel, asiatic moonseed rhizome, tree peony bark, honeysuckle, grape seeds and water are mixed according to the weight ratio of 25: 7: 4:9:12:6: 280, then heating, boiling and boiling for 2.5 hours, and filtering to obtain filtrate for later use;

b. and c, heating and concentrating the filtrate obtained in the step a to 10% of the original volume.

(3) and (2) adding the performance additive A, the performance additive B and water weighed in the step (1) together, stirring uniformly again, and standing for 8 hours.

Example 5

ingredients of raw materials	Parts by weight (parts)
		Moisture-retaining agent	55
Adhesive agent	1.5
		Sweetening agent	0.3
Corrosion inhibitor	0.2
		Friction agent	30
Foaming agent	2
		Essence	1
Preservative	0.08
		Performance additives A	0.5
Performance additives B	3
		Water (W)	9

Comparative example 1

ingredients of raw materials	Parts by weight (parts)
		Moisture-retaining agent	48
Adhesive agent	1.3
		Sweetening agent	0.2
Corrosion inhibitor	0.17
		Friction agent	27
Foaming agent	1.8
		Essence	0.7
Preservative	0.065
		Performance additives B	2
Water (W)	7

This comparative example 1 is different from example 3 only in that the addition of the component A as a performance additive is omitted, except that the steps of the method are the same.

Comparative example 2

ingredients of raw materials	Parts by weight (parts)
		Moisture-retaining agent	48
Adhesive agent	1.3
		Sweetening agent	0.2
Corrosion inhibitor	0.17
		Friction agent	27
Foaming agent	1.8
		Essence	0.7
Preservative	0.065
		Performance additives A	0.4
Water (W)	7

This comparative example 2 is different from example 3 only in that the addition of the component B as a performance additive is omitted, except that the process steps are the same.

Comparative example 3

ingredients of raw materials	Parts by weight (parts)
		Moisture-retaining agent	48
Adhesive agent	1.3
		Sweetening agent	0.2
Corrosion inhibitor	0.17
		Friction agent	27
Foaming agent	1.8
		Essence	0.7
Preservative	0.065
		Water (W)	7

This comparative example 3 is different from example 3 only in that the addition of the components of performance additive A and performance additive B is omitted, except that the process steps are the same.

Control group

The application numbers are: 201811265889.0 discloses a toothpaste for decreasing internal heat, removing halitosis and whitening, which is prepared by the technical proposal of the embodiment 2.

In order to compare the effects of the present invention, the toothpastes of example 3, comparative examples 1 to 3, and the control group were subjected to in vivo tests for tooth whitening effect, and the specific results are shown in table 1 below:

TABLE 1

	Becomes good (%)	Same (%)	Variation (%)
				Example 3	84	16	0
Comparative example 1	49	51	0
				Comparative example 2	60	40	0
Comparative example 3	29	71	0
				Control group	25	75	0

Note: the corresponding test is specifically as follows: 200 healthy males and females were selected as subjects to measure the tooth color before and after the use of the toothpaste. The original tooth color of the subject was measured by the shield eye-EX (SHOFU co. The baseline value (first standard value) was determined and collected by placing the shield eye-EX tip perpendicularly on the tooth surface located 2mm above the bucco-cervical region of the central incisor in the middle of the mesio-distal diameter (maxillary-left side), and carefully illuminating the tooth surface without being illuminated. Then, the subjects brushed their teeth three times a day for 2 months with the toothpastes of example 3, comparative examples 1 to 3, and the control group. During the experiment, food was taken according to the respective eating habits, but on the day of measuring tooth color, coffee, cola and tobacco were prohibited. The results were obtained by measuring the color (second measurement value) after using the toothpastes of example 3, comparative examples 1 to 3, and control group, and comparing and calculating.

As can be seen from the above table 1, the toothpaste of the invention can whiten teeth well, and has high effective rate and stable use effect.

In order to further compare the effects of the invention, the halitosis removing experiment is carried out, specifically:

(one) subject selection: 1. the age is 30-40 years, half of male and half of female, 50 (divided into S1 group, S2 group, S3 group, S4 group, S5 group, 10 persons in each group, and half of male and female in each group); 2. halitosis has lasted for more than half a year; 3. in half a year before the test, the test has the habits of brushing teeth after getting up in the morning and brushing teeth before sleeping in the evening; 4. detecting by Rosenberg nasal smell method, wherein the examiner and the subject face to face with a distance of 10cm, the subject closes mouth, breathes in nose for 1 min, and then opens mouth to breathe lightly, and has similar halitosis symptom; 5. at least 20 teeth; 6. no denture, no appliance; 7. otorhinolaryngology, digestive system, respiratory system and other systemic diseases; 8. no medicine is taken, and no halitosis treatment or tooth and oral disease treatment is carried out; 9. spicy and pungent food is not taken; 10. the food with high sulfur content such as garlic, onion, leek, radish, etc. is not eaten; 10. no alcohol or beverage was consumed the day before the test.

(II) subject distribution: subjects of groups S1, S2, S3, S4 and S5 were each subjected to tooth brushing after rising in the morning and tooth brushing before sleeping in the evening, and for the toothpastes using the above-mentioned examples 2, comparative examples 1 to 3 and control group, the mass concentrations of hydrogen sulfide, methyl mercaptan and dimethyl sulfide of each individual were each measured as the initial mass concentrations of hydrogen sulfide, methyl mercaptan and dimethyl sulfide of each individual by a portable gas chromatograph (Oral Chromatm, ABILIT Co., Japan) before using the toothpastes. Two weeks after using the toothpaste, the mass concentrations of hydrogen sulfide, methyl mercaptan and dimethyl sulfide were measured for each person as the final mass concentrations of hydrogen sulfide, methyl mercaptan and dimethyl sulfide for each person using a portable gas chromatograph (Oral ChromaTM, ABILIT corporation, japan). All subjects were unable to eat, drink, reject chewing gum, brush teeth within 2 hours prior to testing.

(III) the detection method comprises the following steps: the specific detection method for detecting the mass concentration of hydrogen sulfide, methyl mercaptan and dimethyl sulfide by using a portable gas chromatograph (Oral ChromaTM, ABILIT corporation, Japan) comprises the following steps: preheating for 30 minutes, closing the mouth of a subject, breathing for 1 minute with the nose, inserting a plastic injector with the capacity of 1mL into the deep part of the oral cavity, fixing the injector by the upper lip and the lower lip and keeping the closed state, avoiding the injector from contacting the tongue in the process, evacuating initial gas in the injector by pulling and pushing a piston, extracting 1mL of gas in the oral cavity, injecting the gas in the injector into a portable gas chromatograph (the injection amount is 0.5mL), recording the mass concentration of hydrogen sulfide, methyl mercaptan and dimethyl sulfide, carrying out parallel detection for three times on each subject, and taking an average value.

(IV) conversion formula:

hydrogen sulfide decrease rate (%) - (initial mass concentration of hydrogen sulfide-final mass concentration of hydrogen sulfide)/initial mass concentration of hydrogen sulfide × 100%;

adding the average hydrogen sulfide reduction (%) of each person in the test group, and dividing the sum by the total number of persons in the test group;

the methyl mercaptan decrease rate (%) ═ (initial mass concentration of methyl mercaptan-final mass concentration of methyl mercaptan)/initial mass concentration of methyl mercaptan x 100%;

the average methyl mercaptan decrease (%) is the sum of the methyl mercaptan decreases (%) for each individual in the test group divided by the total number of individuals in the test group;

the reduction in the mass% of dimethyl sulfide (initial mass concentration of dimethyl sulfide-final mass concentration of dimethyl sulfide)/initial mass concentration of dimethyl sulfide x 100%;

average reduction (%) in dimethyl sulfide was added to the reduction (%) of each individual in the test group and divided by the total number of individuals in the test group.

(V) data recording and comparing: the average decrease (%) of hydrogen sulfide, the average decrease (%) of methyl mercaptan and the average decrease (%) of dimethyl sulfide obtained from the above groups were recorded and converted, and the specific comparative data are shown in table 2 below:

TABLE 2

	Average decrease of hydrogen sulfide (%)	Mean reduction of methyl mercaptan (%)	Average reduction of dimethyl sulfide (%)
				S1 group	98.24	95.36	85.47
S2 group	89.61	88.43	80.27
				S3 group	82.66	81.34	76.12
S4 group	75.28	83.12	71.45
				S5 group	77.89	80.13	69.84

As can be seen from the above table 2, the toothpaste of the invention can significantly reduce the symptoms of halitosis, and subjects who hear the toothpaste use the toothpaste obviously feel refreshing and comfortable after using the toothpaste for a period of time, and the frequency of symptoms such as gingival excessive internal heat is also obviously reduced, indicating that the toothpaste of the invention has good effects of clearing heat and reducing internal heat.

In conclusion, the toothpaste has strong efficacies of reducing internal heat, removing halitosis and whitening teeth, does not contain irritant additive components, is safe to use, is green and environment-friendly, is suitable for people of all ages, and has high popularization and application values and market competitiveness.

Claims

1. The internal heat-reducing halitosis-removing whitening toothpaste is characterized by being prepared from the following substances in parts by weight:

2. The toothpaste as claimed in claim 1, wherein the toothpaste is prepared from the following materials in parts by weight:

3. The toothpaste as claimed in claim 2, wherein the toothpaste is prepared from the following materials in parts by weight:

4. The toothpaste as claimed in any one of claims 1 to 3, wherein the humectant is glycerin or sorbitol; the adhesive is sodium carboxymethyl cellulose; the sweetening agent is saccharin sodium; the corrosion inhibitor is sodium nitrate; the friction agent is calcite or aluminum hydroxide; the foaming agent is sodium lauryl sulfate; the preservative is sodium benzoate.

5. The toothpaste as claimed in any one of claims 1 to 3, wherein the preparation method of the performance additive A comprises the following steps:

6. The toothpaste as claimed in claim 5, wherein the extract in step 1) is composed of the following materials in parts by weight: 3-5 parts of sodium pyrophosphate, 2-6 parts of algal polysaccharide and 80-85 parts of edible alcohol; the concentration of the edible alcohol is 60%; and the frequency of the ultrasonic wave is controlled to be 520-580 kHz during ultrasonic leaching treatment.

7. The toothpaste as claimed in claim 5, wherein the freezing temperature of the freeze-drying treatment in step 4) is-10 to-15 ℃.

8. The toothpaste as claimed in any one of claims 1 to 3, wherein the preparation method of the performance additive B comprises the following steps:

9. A method for preparing the toothpaste with effects of reducing internal heat, removing halitosis and whitening according to any one of claims 1-8, comprising the following steps: