CN111759882A - Pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion and preparation method thereof - Google Patents

Pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion and preparation method thereof Download PDF

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CN111759882A
CN111759882A CN202010704546.0A CN202010704546A CN111759882A CN 111759882 A CN111759882 A CN 111759882A CN 202010704546 A CN202010704546 A CN 202010704546A CN 111759882 A CN111759882 A CN 111759882A
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traditional chinese
chinese medicine
intervertebral disc
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章军
李少龙
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

The invention provides a pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion and a preparation method thereof, relating to the technical field of traditional Chinese medicines; relates to a pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion, which is prepared from the following raw materials in parts by weight: 10-15 parts of eucommia ulmoides, 12-15 parts of achyranthes bidentata, 13-15 parts of radix angelicae pubescentis, 12-18 parts of caulis spatholobi, 10-12 parts of deerhorn glue, 10-15 parts of frankincense, 12-18 parts of lycopodium clavatum and 6-9 parts of safflower; also relates to a preparation method of the pure traditional Chinese medicine transdermal liniment for treating the protrusion of intervertebral disc, which comprises the following steps: s1, putting eucommia ulmoides, achyranthes bidentata, radix angelicae pubescentis, caulis spatholobi, deer-horn glue, frankincense, lycopodium clavatum and safflower in parts by weight into a stone mortar, and pounding the materials into powder; s2, soaking the mashed mixed powder in 50-100 parts by weight of 75% alcohol for 20-25 days. The embodiment adopts the traditional Chinese medicine preparation with small side effect, adopts effective raw materials and reasonable proportion, and has good curative effect; the preparation is simple, and the traditional Chinese medicine composition is fully dissolved by adopting alcohol, so that the traditional Chinese medicine composition fully exerts the drug effect, improves the treatment effect and plays a role in sterilization and disinfection.

Description

Pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a pure traditional Chinese medicine transdermal liniment for treating intervertebral disc herniation and a preparation method thereof.
Background
The intervertebral disc protrusion is one of the more common diseases, although symptoms are not particularly obvious in some cases of mild patients, once the patients have a long-time sitting or waist fatigue and the like, the pain of the parts such as the waist, the lower limbs and the like is easily caused, and the quality of life and work is influenced; the pain and discomfort symptoms of serious patients are obvious and frequently occur, and the normal work and life are seriously influenced. Therefore, the medicine for effectively treating the protrusion of the intervertebral disc and the preparation method thereof are necessary for the majority of patients.
Some existing medicines for treating the herniated disk are prepared by combining western medicines or multiple traditional Chinese medicines according to a certain proportion, and the prepared medicines are tablets, pills, granules and the like; the existing preparation method of the medicament for treating the herniated disk comprises the steps of decocting and/or stewing and the like, and various traditional Chinese medicine compositions are dissolved by adopting a hydrosolvent and the like.
In the process of implementing the embodiment, the inventor finds at least the following problems:
some existing medicines for treating the herniated disk adopt western medicines with large side effects; in addition, although the traditional Chinese medicine composition is adopted, the traditional Chinese medicine composition is mostly in the form of non-external liniment, and the use is relatively unsafe.
In the existing preparation method of the medicament for treating the protrusion of intervertebral disc, the process is relatively complex and more steps are needed, and some traditional Chinese medicine compositions cannot be fully dissolved by adopting solvents such as water and the like, so that the traditional Chinese medicine compositions can not fully exert the drug effect, and can not play a role in disinfection and sterilization.
Disclosure of Invention
The invention aims to provide a pure traditional Chinese medicine transdermal liniment for treating herniated disk, and aims to solve the technical problems that western medicines for treating herniated disk have large side effects, most traditional Chinese medicines are in a non-liniment form, and the use is relatively unsafe.
In order to solve the technical problems, the technical scheme of the invention is as follows:
the invention provides a pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion, which is prepared from the following raw materials in parts by weight: 10-15 parts of eucommia bark, 12-15 parts of achyranthes root, 13-15 parts of pubescent angelica root, 12-18 parts of suberect spatholobus stem, 10-12 parts of deerhorn glue, 10-15 parts of frankincense, 12-18 parts of common clubmoss herb and 6-9 parts of safflower.
Further, the feed is prepared from the following raw materials in parts by weight: 12 parts of eucommia bark, 14 parts of achyranthes root, 15 parts of pubescent angelica root, 18 parts of suberect spatholobus stem, 12 parts of deerhorn glue, 12 parts of frankincense, 12-18 parts of common clubmoss herb and 6 parts of safflower.
The beneficial effect of this scheme does:
the embodiment provides a pure traditional Chinese medicine transdermal liniment for treating the protrusion of intervertebral disc, which adopts a pure traditional Chinese medicine preparation and has small side effect; the effective raw materials and reasonable proportion are adopted, so that the treatment effect on the herniated disk is good; the liniment is used as an external liniment, and is safer to use.
The invention also aims to provide a preparation method of the pure traditional Chinese medicine transdermal liniment for treating the intervertebral disc protrusion, which aims to solve the technical problems that the preparation process is relatively complex and has more steps, the traditional Chinese medicine composition cannot be fully dissolved by adopting solvents such as water and the like, the drug effect is promoted to be fully exerted, and the disinfection and sterilization effects cannot be realized in the existing preparation method of the pure traditional Chinese medicine transdermal liniment for treating the intervertebral disc protrusion.
In order to solve the technical problems, the technical scheme of the invention is as follows:
the invention also provides a preparation method of the pure traditional Chinese medicine transdermal liniment for treating the protrusion of intervertebral disc, which comprises the following steps:
s1, putting eucommia ulmoides, achyranthes bidentata, radix angelicae pubescentis, caulis spatholobi, deer-horn glue, frankincense, lycopodium clavatum and safflower in parts by weight into a stone mortar, and pounding the materials into powder;
s2, soaking the mashed mixed powder in 50-100 parts by weight of 75% alcohol for 20-25 days.
Further, the volume fraction of the alcohol in step S2 is 75%.
The beneficial effect of this scheme does:
the embodiment provides a preparation method of a pure traditional Chinese medicine transdermal liniment for treating herniated disk, which comprises the steps of grinding raw materials into powder, and soaking the powder for 20-25 days by using 75% alcohol in a certain proportion; on one hand, grinding into powder is beneficial to fully mixing all the medicines, and on the other hand, the efficacy and the synergistic effect of all the components can be fully exerted after the medicines are soaked in alcohol for the days. In addition, alcohol has the effect of sterilization and disinfection, and optionally, the concentration of alcohol in the embodiment is 75%, so that the alcohol is more suitable for human skin.
Therefore, the preparation method of the pure traditional Chinese medicine transdermal liniment for treating the herniated disk has simple preparation process and few steps, and the traditional Chinese medicine composition can be fully dissolved by adopting the alcohol, so that the medicine effect is fully exerted, the treatment effect is improved, and the effects of disinfection and sterilization can be achieved.
The effects of the medicines in the invention are as follows:
eucommia ulmoides: it has effects in nourishing liver and kidney, strengthening muscle and bone, and preventing miscarriage. It is indicated for soreness and pain of lumbar and knees, atrophy and weakness of feet and knees, dribbling urination, itching of vulva, vaginal bleeding, threatened abortion, and hypertension.
Achyranthes root: the roots are used as the medicine, unprocessed, and activate blood and dredge channels; treating puerperal abdominal pain, menoxenia, amenorrhea, epistaxis, toothache due to deficiency fire, loempe and edema; for use in cooking, liver and kidney are tonified, waist and knee are strengthened; it is indicated for soreness and pain of waist and knees, liver and kidney deficiency, traumatic injury, blood stasis and pain.
Radix angelicae pubescentis: can be used for treating arthralgia due to wind-cold-dampness, lumbago, gonalgia, headache due to wind-cold-yin deficiency, and headache due to wind-cold-dampness.
Caulis spatholobi: the stem used as a medicine is one of the main sources of the traditional Chinese medicine caulis spatholobi and has the efficacies of dispelling wind and activating blood circulation, relaxing tendons and activating collaterals. It can be used for treating soreness of waist and knees, numbness, paralysis, and menoxenia.
Deer-horn glue: to warm and nourish liver and kidney, replenish vital essence and nourish blood. Can be used for treating blood deficiency, dizziness, soreness of waist and knees, asthenia, and marasmus.
Frankincense: promote blood circulation, move qi and alleviate pain, resolve swelling and promote tissue regeneration. Can be used for treating thoracic obstruction, cardialgia, epigastralgia, dysmenorrhea, amenorrhea, puerperal blood stasis, abdominal pain, rheumatalgia, spasm of muscles and tendons, traumatic injury, carbuncle, swelling, and pyocutaneous disease
B, common clubmoss herb: has effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles and activating collaterals. Can be used for treating joint pain and difficulty in flexion and extension.
Safflower: promoting blood circulation, dredging channels, removing blood stasis and relieving pain. It is indicated for amenorrhea, abdominal mass, dystocia, dead fetus, postpartum lochiorrhea, pain due to blood stasis, carbuncle, swelling and traumatic injury.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments.
Thus, the following detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
The invention provides a pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion, which is prepared from the following raw materials in parts by weight: 10 parts of eucommia bark, 12 parts of achyranthes root, 15 parts of pubescent angelica root, 18 parts of suberect spatholobus stem, 12 parts of deerhorn glue, 11 parts of frankincense, 18 parts of common clubmoss herb and 6 parts of safflower.
The preparation method of the pure traditional Chinese medicine transdermal liniment for treating the herniated disk comprises the following steps:
s1, putting eucommia ulmoides, achyranthes bidentata, radix angelicae pubescentis, caulis spatholobi, deer-horn glue, frankincense, lycopodium clavatum and safflower in parts by weight into a stone mortar, and pounding the materials into powder;
s2, the mashed mixed powder is put into 75% alcohol with the weight of 50 parts to be soaked for 20 days for use.
Example two
The invention provides a pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion, which is prepared from the following raw materials in parts by weight: 12 parts of eucommia bark, 14 parts of achyranthes root, 15 parts of pubescent angelica root, 18 parts of suberect spatholobus stem, 12 parts of deerhorn glue, 12 parts of frankincense, 12-18 parts of common clubmoss herb and 6 parts of safflower.
The preparation method of the pure traditional Chinese medicine transdermal liniment for treating the herniated disk comprises the following steps:
s1, putting eucommia ulmoides, achyranthes bidentata, radix angelicae pubescentis, caulis spatholobi, deer-horn glue, frankincense, lycopodium clavatum and safflower in parts by weight into a stone mortar, and pounding the materials into powder;
s2, the mashed mixed powder is put into 75% alcohol of 100 parts by weight to be soaked for 25 days.
EXAMPLE III
The invention provides a pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion, which is prepared from the following raw materials in parts by weight: 15 parts of eucommia bark, 12 parts of achyranthes root, 15 parts of pubescent angelica root, 18 parts of suberect spatholobus stem, 10 parts of deerhorn glue, 10 parts of frankincense, 18 parts of common clubmoss herb and 9 parts of safflower.
The preparation method of the pure traditional Chinese medicine transdermal liniment for treating the herniated disk comprises the following steps:
s1, putting eucommia ulmoides, achyranthes bidentata, radix angelicae pubescentis, caulis spatholobi, deer-horn glue, frankincense, lycopodium clavatum and safflower in parts by weight into a stone mortar, and pounding the materials into powder;
s2, the mashed mixed powder is put into 75% alcohol with the weight portion of 80 to be soaked for 20 days for use.
1 clinical cases
50 patients with confirmed disc herniation were selected as the observation group, wherein 37 men and 13 women in the observation group were aged 40-65 years and the course of disease was 1-12 months.
2 method of treatment
The traditional Chinese medicine transdermal liniment prepared by the embodiment of the invention is applied to acupuncture points of skin three times a day, 30 days are a treatment course, and the treatment period is 3 treatment courses.
3 judgment of therapeutic effects
According to the standard of the curative effect of the diagnosis of the traditional Chinese medicine symptoms, the following standards are determined:
and (3) curing: the affected part of the patient has no pain symptom, and the normal work and life are recovered.
Improvement: the patient's condition is effectively improved, and the pain of the affected part is not obvious when sitting properly or doing housework.
The disease is not cured: no obvious change before and after clinical symptoms.
4 therapeutic results
After one treatment cycle, the results of the treatment for the patients in the observation group are detailed in the following table:
group name Number of examples Cure/example Improvement/example Non-healing/example Total effective rate
Observation group 50 35 11 4 92％
As can be seen from the above table, the observation groups have good curative effects, no obvious repeated condition occurs during the clinical observation period, and some basic indexes of the body of the patient have no obvious difference before and after treatment.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims (4)

1. A pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion is characterized by being prepared from the following raw materials in parts by weight: 10-15 parts of eucommia bark, 12-15 parts of achyranthes root, 13-15 parts of pubescent angelica root, 12-18 parts of suberect spatholobus stem, 10-12 parts of deerhorn glue, 10-15 parts of frankincense, 12-18 parts of common clubmoss herb and 6-9 parts of safflower.
2. The pure traditional Chinese medicine transdermal liniment for treating intervertebral disc herniation according to claim 1, is characterized by being prepared from the following raw materials in parts by weight: 12 parts of eucommia bark, 14 parts of achyranthes root, 15 parts of pubescent angelica root, 18 parts of suberect spatholobus stem, 12 parts of deerhorn glue, 12 parts of frankincense, 12-18 parts of common clubmoss herb and 6 parts of safflower.
3. A preparation method of a pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion, which is characterized by comprising the preparation method of the pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion of claim 1 or 2, and comprises the following steps:
s1, putting eucommia ulmoides, achyranthes bidentata, radix angelicae pubescentis, caulis spatholobi, deer-horn glue, frankincense, lycopodium clavatum and safflower in parts by weight into a stone mortar, and pounding the materials into powder;
s2, soaking the mashed mixed powder in 50-100 parts by weight of 75% alcohol for 20-25 days.
4. The method for preparing a pure Chinese medicinal transdermal liniment for treating intervertebral disc protrusion according to claim 4, wherein the volume fraction of the alcohol in step S2 is 75%.
CN202010704546.0A 2020-07-21 2020-07-21 Pure traditional Chinese medicine transdermal liniment for treating intervertebral disc protrusion and preparation method thereof Pending CN111759882A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1254575A (en) * 1998-11-20 2000-05-31 王秀琴 Exterior-applied powder medicine for treating lumbar intervertebral disk protrusion and preparing process
CN102872238A (en) * 2012-09-06 2013-01-16 马加明 Medicine for treating osteoarthrosis and preparation method thereof
CN104922205A (en) * 2015-04-23 2015-09-23 秦宝兰 Traditional Chinese medicine formula for treating lumbar disc herniation
CN107007724A (en) * 2017-04-20 2017-08-04 安阳古方医药科技有限公司 A kind of Traditional Chinese medice healthy liquid and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1254575A (en) * 1998-11-20 2000-05-31 王秀琴 Exterior-applied powder medicine for treating lumbar intervertebral disk protrusion and preparing process
CN102872238A (en) * 2012-09-06 2013-01-16 马加明 Medicine for treating osteoarthrosis and preparation method thereof
CN104922205A (en) * 2015-04-23 2015-09-23 秦宝兰 Traditional Chinese medicine formula for treating lumbar disc herniation
CN107007724A (en) * 2017-04-20 2017-08-04 安阳古方医药科技有限公司 A kind of Traditional Chinese medice healthy liquid and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
师彬: "《治疗颈椎间盘突出症》", 31 March 2018, 山东科学技术出版社 *
郑志波，等: "三步疗法治疗腰椎间盘突出症152例", 《新疆中医药》 *
钱国栋，等: "综合治疗老年性腰椎间盘突出症的疗效观察", 《安徽医学》 *

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Application publication date: 20201013