CN111678904A - Brain glioma boundary determining device - Google Patents
Brain glioma boundary determining device Download PDFInfo
- Publication number
- CN111678904A CN111678904A CN202010531981.8A CN202010531981A CN111678904A CN 111678904 A CN111678904 A CN 111678904A CN 202010531981 A CN202010531981 A CN 202010531981A CN 111678904 A CN111678904 A CN 111678904A
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- 201000007983 brain glioma Diseases 0.000 title claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 230000000149 penetrating effect Effects 0.000 claims description 7
- 238000004140 cleaning Methods 0.000 abstract description 3
- 230000003749 cleanliness Effects 0.000 abstract description 3
- 238000001514 detection method Methods 0.000 description 7
- 238000007667 floating Methods 0.000 description 6
- 208000032612 Glial tumor Diseases 0.000 description 5
- 206010018338 Glioma Diseases 0.000 description 5
- 239000010865 sewage Substances 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 238000001069 Raman spectroscopy Methods 0.000 description 3
- 238000001237 Raman spectrum Methods 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 208000007660 Residual Neoplasm Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000029578 entry into host Effects 0.000 description 1
- 238000011221 initial treatment Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000010837 poor prognosis Methods 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
Images
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
Abstract
The invention discloses a brain glioma boundary determining device which comprises an external box body, wherein an internal bucket body is arranged in the external box body, sliding plates are symmetrically fixed on two sides of the bottom of the internal bucket body, the bottom ends of the two sliding plates are connected with sliding rails in a sliding mode, two first sliding retractors are fixed between the bottom wall of one sliding rail and the inner side wall of the external box body, and a first sliding retractor and a threaded retractor are fixed between the bottom wall of the other sliding rail and the inner side wall of the external box body. The back that finishes can be placed at the sample to the setting of this scheme through each structure, carries out convenient stable and accurate position control to it to the convenience detects the different position region of sample, takes out the back at the sample simultaneously, can realize making things convenient for efficient cleaning to the inside bucket body of placing the sample, guarantees the inside cleanliness of inside bucket body, makes things convenient for reuse next time.
Description
Technical Field
The invention relates to the technical field of medical treatment, in particular to a brain glioma boundary determining device.
Background
Among brain tumors, brain glioma is the most malignant tumor, which has the biological characteristic of invasive growth, and is difficult to completely cut through by operation, but the degree of residual tumor load after the operation directly influences the prognosis.
Surgical resection of brain gliomas is currently the primary treatment. However, postoperative tumor residues are a major cause of recurrence and poor prognosis. The traditional tumor positioning technology has the defects of inaccurate positioning, long positioning time, invasive and complex operation, high price, toxic and side effects of contrast agents on bodies and the like.
By way of search, chinese patent No. (CN108896531B) discloses a brain glioma boundary determining apparatus including: the object carrying part comprises an object carrying platform, a sealing cover and an air bag, the object carrying platform is spherical, a sample adding port is formed in the top of the sphere, the sealing cover is arranged on the object carrying platform and used for sealing the sample adding port, the air bag is arranged in the object carrying platform, and an inflation port of the air bag is arranged on the outer surface of the object carrying platform; the Raman spectrum detection part comprises a laser emitter, a dichroic mirror, a confocal microscope, an optical filter, a detector and a display. The brain glioma boundary determining device can rapidly, accurately and non-invasively determine the boundary of glioma-infiltrating tissue and non-glioma-infiltrating tissue.
The above device for determining the brain glioma boundary in the prior art still has the following disadvantages: when the device is used, if the position of a sample needs to be adjusted, complicated and complicated operations need to be carried out, and in the operation, the position of the sample cannot be accurately controlled, so that the position of the sample cannot be larger, and the subsequent detection is difficult; in addition, after the detection is finished, the spherical object stage is troublesome to clean, the cleanliness is not easy to guarantee, and the secondary detection is influenced, so that the prior art needs to be improved.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a brain glioma boundary determining device.
In order to achieve the purpose, the invention adopts the following technical scheme:
the brain glioma boundary determining device comprises an external box body, wherein an internal bucket body is arranged inside the external box body, sliding plates are symmetrically and fixedly arranged on two sides of the bottom of the internal bucket body, the bottom ends of the sliding plates are all slidably connected with sliding rails, one sliding rail is fixedly provided with two first sliding expansion pieces on the bottom wall of the sliding rail and between the inner side walls of the external box body, the other sliding rail is fixedly provided with a first sliding expansion piece and a threaded expansion piece on the bottom wall of the sliding rail and between the inner side walls of the external box body, each first sliding expansion piece comprises a plurality of sleeves which are mutually sleeved and slidably connected, each sleeve which is far away from one side of the internal bucket body in the first sliding expansion piece is fixedly arranged on the inner wall of the external box body, each threaded expansion piece comprises a plurality of threaded pipes which are mutually sleeved and connected in a threaded manner, and the threaded pipes which are far away from one side of the internal bucket body in the threaded expansion piece extend out of the external box body and are connected The rotating rod is fixed at the tail end of the threaded pipe, the first hand wheel is fixed at the tail end of the rotating rod, the threaded rod is connected with the bottom of one sliding plate in a threaded manner, one end of the threaded rod extends to the outer side of the outer box body and is provided with the second hand wheel,
a drain outlet is formed in the bottom wall of the inner bucket body in a penetrating mode, a drain outlet is also formed in the bottom wall of the outer box body in a penetrating mode, a hose is commonly installed between the two drain outlets, and a drain pipe corresponding to the drain outlet and the hose is installed on the bottom wall of the outer box body;
install circular pipe on the inside wall on inside bucket body top, install the shower nozzle on the inside wall of circular pipe, and the equal slope of every shower nozzle sets up, circular pipe has the water pump through advancing water piping connection, the inside wall of inside bucket body bottom is fixed with the gasbag through a plurality of bracing pieces, the gasbag has the air pump through intake-tube connection, the gasbag upside is equipped with the float board, the upside of float board is equipped with the deflector fixed with the inner wall of inside bucket body, the deflector is to matcing each other with the float board, the symmetry all around of float board diapire is equipped with a plurality of second slip expansion bend, every the second slip expansion bend all includes the sliding sleeve of establishing in the sub-pole outside with the fixed sub-pole of float board and slip cap, and the bottom of slide pipe is fixed with the inside wall of inside bucket body.
Further, slewing mechanism includes and establishes fixed ring with the screwed pipe cover of screw thread expansion bend, the torus is fixed with a plurality of stop block to one side of outside box lateral wall, set up on the lateral wall of outside box with stop block assorted annular spout.
Furthermore, the limiting slide block is of a T-shaped structure.
Furthermore, the cross section of the slide rail is of a U-shaped structure.
Further, the water outlet of the spray head is inclined downwards by 30-60 degrees.
Furthermore, a valve is arranged at the tail end of the sewage discharge pipe.
Furthermore, the both ends of threaded rod all are connected with the fixed plate through the bearing rotation, two the fixed plate is all fixed on the roof of the slide rail of homonymy.
Further, the tail end of the threaded rod extends to the outer side of the external box body, and a transverse groove is formed in the side wall of the external box body in a penetrating mode.
Compared with the prior art, the invention has the beneficial effects that:
the back that finishes can be placed at the sample to the setting of this scheme through each structure, carries out convenient stable and accurate position control to it to the convenience detects the different position region of sample, takes out the back at the sample simultaneously, can realize making things convenient for efficient cleaning to the inside bucket body of placing the sample, guarantees the inside cleanliness of inside bucket body, makes things convenient for reuse next time.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.
Fig. 1 is a schematic view of an overall structure of a brain glioma boundary determining device according to the present invention;
fig. 2 is a schematic diagram of an internal structure of a brain glioma boundary determining device according to the present invention;
FIG. 3 is an enlarged view of the structure of portion A of FIG. 2;
FIG. 4 is an enlarged view of the structure of portion B of FIG. 2;
FIG. 5 is an enlarged view of the structure of portion C of FIG. 2;
FIG. 6 is an enlarged view of a portion D of the structure of FIG. 2;
fig. 7 is a side view of the installation of the threaded rod on the slide rail.
In the figure: the device comprises an external box body 1, an internal bucket body 2, a water pump 3, a water inlet pipe 31, an air pump 4, an air inlet pipe 41, an air bag 5, a floating plate 6, a guide plate 7, a support rod 8, a hose 9, a sewage discharge pipe 10, a circular pipe 11, a spray head 12, a first sliding expansion piece 13, a threaded expansion piece 14, a circular ring 15, a limiting slide block 16, a rotating rod 17, a sliding rail 18, a sliding plate 19, a threaded rod 20, a second sliding expansion piece 21, a fixed plate 22 and a transverse groove 23.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Referring to fig. 1-7, a glioma boundary determining device includes an external box 1, and further includes a raman spectrum detection portion, where the raman spectrum detection portion includes a laser emitter, a dichroic mirror, a confocal microscope, an optical filter, a detector, and a display, which are disclosed in the prior patent (CN108896531B), and therefore, no further description is given in this embodiment.
The inside of the external box body 1 is provided with an internal bucket body 2, sliding plates 19 are symmetrically fixed on two sides of the bottom of the internal bucket body 2, the bottom ends of the two sliding plates 19 are respectively connected with a sliding rail 18 in a sliding manner, two first sliding expanders 13 are jointly fixed between the bottom wall of one sliding rail 18 and the inner side wall of the external box body 1, a first sliding expander 13 and a threaded expander 14 are jointly fixed between the bottom wall of the other sliding rail 18 and the inner side wall of the external box body 1, each first sliding expander 13 comprises a plurality of sleeves which are mutually sleeved and are in sliding connection, the sleeve on one side of the first sliding expander 13 far away from the internal bucket body 2 is fixed with the inner wall of the external box body 1, the threaded expander 14 comprises a plurality of threaded pipes which are mutually sleeved and in threaded connection, the threaded pipe on one side of the threaded expander 14 far away from the internal bucket body 2 extends to the outer side of the external box body 1 and is rotatably connected with the external box body 1 through a rotating, a rotating rod 17 is fixed at the tail end of the threaded pipe, a first hand wheel is fixed at the tail end of the rotating rod 17, a threaded rod 20 is connected with the bottom of one sliding plate 19 in a threaded manner, one end of the threaded rod 20 extends to the outer side of the outer box body 1 and is provided with a second hand wheel,
a drain outlet is arranged on the bottom wall of the inner bucket body 2 in a penetrating way, a drain outlet is also arranged on the bottom wall of the outer box body 1, a hose 9 is commonly arranged between the two drain outlets, and a drain pipe 10 corresponding to the drain outlet and the hose 9 is arranged on the bottom wall of the outer box body 1;
install circular pipe 11 on the inside wall on 2 tops of inside bucket body, install shower nozzle 12 on circular pipe 11's the inside wall, and every shower nozzle 12 all inclines to set up, circular pipe 11 is connected with water pump 3 through inlet tube 31, the inside wall of 2 bottoms of inside bucket body is fixed with gasbag 5 through a plurality of bracing pieces 8, gasbag 5 is connected with air pump 4 through intake pipe 41, 5 upsides of gasbag are equipped with unsteady board 6, the upside of unsteady board 6 is equipped with deflector 7 fixed with the inner wall of inside bucket body 2, deflector 7 is to matcing with unsteady board 6 each other, the symmetry all around of unsteady 6 diapire of unsteady board is equipped with a plurality of second slip expansion bend 21, every second slip expansion bend 21 all include with unsteady 6 fixed sub-pole and the sliding sleeve of establishing in the sub-pole outside, and the bottom of slide pipe is fixed with the inside wall of inside bucket body 2.
Further, slewing mechanism includes and establishes fixed ring 15 with the screw thread pipe box of screw thread expansion bend 14, and ring 15 is fixed with a plurality of stop block 16 towards one side of outside box 1 lateral wall, offers on the lateral wall of outside box 1 with stop block 16 assorted annular spout.
Further, the limiting slide block 16 is in a T-shaped structure.
Further, the cross section of the slide rail 18 is a U-shaped structure.
Further, the water outlet of the spray head 12 is inclined downwards by 30-60 degrees.
Further, a valve is installed at the end of the sewage drain pipe 10.
Further, both ends of the threaded rod 20 are rotatably connected with fixing plates 22 through bearings, and the two fixing plates 22 are fixed on the top wall of the slide rail 18 on the same side.
Further, the end of the threaded rod 20 extends to the outside of the external box 1, and a transverse groove 23 is formed on the side wall of the external box 1 in a penetrating manner.
The working principle and the using process of the invention are as follows: the air pump 4 and the air inlet pipe 41 (the pressure relief valve is installed on the air inlet pipe 41) inflate the air bag 5, the expanded air bag 5 pushes up the floating plate 6, the floating plate and the guide plate 7 are mutually matched in a splicing manner, a sample is placed on a placing surface formed by the floating plate 6 and the guide plate 7, and then subsequent operations are carried out, namely the contents disclosed in the prior patent (CN108896531B), such as: the laser emitter emits laser, the laser is reflected by the dichroic mirror, emitted light is collected by the confocal microscope and irradiates on a specimen, Raman scattering occurs on the specimen, scattered light passes through the dichroic mirror and then vertically transmits to the optical filter, the optical filter filters interference scattered light, Raman scattered light is obtained, Raman scattered light signals are detected and checked, a display displays detection results, and boundary information of glioma infiltrated tissues and non-glioma infiltrated tissues is obtained.
After the operation is finished, the sample is moved out of the inner bucket body 2, then the gas in the air bag 5 is exhausted, at the moment, the floating plate 6 can be lowered to be separated from the guide plate 7, then the water is injected into the circular pipe 11 through the water pump 3 and the water pipe 31, water flow is sprayed out through the spray head 12, the floating plate 6, the guide plate 7 and the inner bucket body 2 are cleaned, and after the cleaning, a valve on the sewage discharge pipe 10 is opened, and sewage is discharged.
In order to adjust the position of sample in inside bucket 2, conveniently observe different parts, the holistic position of inside bucket 2 is adjusted to the accessible, specifically is: one of the threaded pipes of the threaded expansion piece 14 is driven to rotate through the first hand wheel and the rotating rod 17, the threaded pipes are in threaded fit with the threaded pipes, so that the length of the threaded expansion piece 14 is adjusted, then the sliding rail 18, the sliding plate 19 and the inner bucket body 2 can be pulled or pushed to integrally move horizontally (can be understood as moving leftwards or rightwards in fig. 2), when the threaded expansion piece 14 extends, the first sliding expansion pieces 13 on the same side extend, and the two first sliding expansion pieces 13 opposite to the threaded expansion pieces 14 contract.
The threaded rod 20 is driven to rotate by the second hand wheel, the threaded rod 20 is in threaded fit with the sliding plate 19, and the sliding plate 19 and the inner bucket body 2 are controlled to integrally move horizontally (which can be understood as forward or backward movement in fig. 2), wherein the horizontal movement and the horizontal movement are in the same plane and are perpendicular to each other.
The position adjustment of the inner bucket body 2 and the inner sample is completed, and different parts of the sample can be observed conveniently.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (8)
1. A brain glioma boundary determining device comprises an external box body (1), and is characterized in that an internal bucket body (2) is arranged inside the external box body (1), sliding plates (19) are symmetrically fixed on two sides of the bottom of the internal bucket body (2), sliding rails (18) are connected to the bottom ends of the two sliding plates (19) in a sliding mode, two first sliding expanders (13) are jointly fixed between the bottom wall of one sliding rail (18) and the inner side wall of the external box body (1), a first sliding expander (13) and a threaded expander (14) are jointly fixed between the bottom wall of the other sliding rail (18) and the inner side wall of the external box body (1), each first sliding expander (13) comprises a plurality of sleeves which are sleeved with each other and are in sliding connection, and the sleeves far away from one side of the internal bucket body (2) in each first sliding expander (13) are fixed to the inner wall of the external box body (1), the threaded expansion piece (14) comprises a plurality of threaded pipes which are sleeved with each other and are in threaded connection, the threaded pipe which is far away from one side of the inner bucket body (2) in the threaded expansion piece (14) extends to the outer side of the outer box body (1) and is rotationally connected with the outer box body (1) through a rotating mechanism, a rotating rod (17) is fixed at the tail end of the threaded pipe, a first hand wheel is fixed at the tail end of the rotating rod (17), a threaded rod (20) is in threaded connection with the bottom of one of the sliding plates (19), one end of the threaded rod (20) extends to the outer side of the outer box body (1) and is provided with a second hand wheel,
a drain outlet is formed in the bottom wall of the inner bucket body (2) in a penetrating mode, a drain outlet is also formed in the bottom wall of the outer box body (1), a hose (9) is installed between the two drain outlets, and a drain pipe (10) corresponding to the drain outlet and the hose (9) is installed on the bottom wall of the outer box body (1);
install circular pipe (11) on the inside wall on inside bucket body (2) top, install shower nozzle (12) on the inside wall of circular pipe (11), and every shower nozzle (12) all inclines to set up, circular pipe (11) are connected with water pump (3) through inlet tube (31), the inside wall of inside bucket body (2) bottom is fixed with gasbag (5) through a plurality of bracing pieces (8), gasbag (5) are connected with air pump (4) through intake pipe (41), gasbag (5) upside is equipped with unsteady board (6), the upside of unsteady board (6) is equipped with deflector (7) fixed with the inner wall of inside bucket body (2), deflector (7) and unsteady board (6) are each other to matching, the symmetry all around of unsteady board (6) diapire is equipped with a plurality of second slip expansion bend (21), every second slip expansion bend (21) all include with unsteady board (6) fixed sub-rod and slip cover establish the sub-rod outside The sliding sleeve, and the bottom of slide tube is fixed with the inside wall of inside bucket body (2).
2. The brain glioma boundary determining device according to claim 1, wherein the rotating mechanism comprises a circular ring (15) fixedly arranged with a threaded pipe sleeve of the threaded expansion piece (14), a plurality of limiting sliding blocks (16) are fixedly arranged on one side of the circular ring (15) facing to the outer side wall of the external box body (1), and an annular sliding groove matched with the limiting sliding blocks (16) is arranged on the outer side wall of the external box body (1).
3. The brain glioma boundary determining device of claim 2 wherein the stop slider (16) is of a T-shaped configuration.
4. The brain glioma boundary determining device of claim 1 wherein the cross-section of the sliding rail (18) is a U-shaped structure.
5. The brain glioma boundary defining device of claim 1 wherein the outlet of the nozzle (12) is angled downward 30-60 degrees.
6. The brain glioma boundary determining device of claim 1 wherein the end of the drain pipe (10) is provided with a valve.
7. The brain glioma boundary determining device of claim 1, wherein both ends of the threaded rod (20) are rotatably connected with fixing plates (22) through bearings, and the two fixing plates (22) are fixed on the top wall of the slide rail (18) on the same side.
8. The brain glioma boundary determining device according to claim 1 or 7, wherein the end of the threaded rod (20) extends to the outside of the outer box (1), and a transverse groove (23) is formed in the side wall of the outer box (1) in a penetrating manner.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010531981.8A CN111678904A (en) | 2020-06-11 | 2020-06-11 | Brain glioma boundary determining device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010531981.8A CN111678904A (en) | 2020-06-11 | 2020-06-11 | Brain glioma boundary determining device |
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| CN111678904A true CN111678904A (en) | 2020-09-18 |
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Application publication date: 20200918 |