CN111676123A - Medium-sized high mass transfer circulating type ventilation fermentation tank - Google Patents
Medium-sized high mass transfer circulating type ventilation fermentation tank Download PDFInfo
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- CN111676123A CN111676123A CN202010730602.8A CN202010730602A CN111676123A CN 111676123 A CN111676123 A CN 111676123A CN 202010730602 A CN202010730602 A CN 202010730602A CN 111676123 A CN111676123 A CN 111676123A
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- 238000000855 fermentation Methods 0.000 title claims abstract description 69
- 230000004151 fermentation Effects 0.000 title claims abstract description 69
- 238000009423 ventilation Methods 0.000 title claims abstract description 33
- 238000009826 distribution Methods 0.000 claims abstract description 23
- 238000001816 cooling Methods 0.000 claims abstract description 8
- 238000002347 injection Methods 0.000 claims abstract description 7
- 239000007924 injection Substances 0.000 claims abstract description 7
- 238000002156 mixing Methods 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 3
- 235000017166 Bambusa arundinacea Nutrition 0.000 abstract description 9
- 235000017491 Bambusa tulda Nutrition 0.000 abstract description 9
- 241001330002 Bambuseae Species 0.000 abstract description 9
- 235000015334 Phyllostachys viridis Nutrition 0.000 abstract description 9
- 239000011425 bamboo Substances 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 7
- 238000006243 chemical reaction Methods 0.000 abstract description 6
- 238000010907 mechanical stirring Methods 0.000 abstract description 2
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 239000007789 gas Substances 0.000 description 21
- 239000007788 liquid Substances 0.000 description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 5
- 239000001301 oxygen Substances 0.000 description 5
- 229910052760 oxygen Inorganic materials 0.000 description 5
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- 238000005265 energy consumption Methods 0.000 description 3
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241001052560 Thallis Species 0.000 description 1
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- 230000003115 biocidal effect Effects 0.000 description 1
- 239000000498 cooling water Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
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- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
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- 238000011031 large-scale manufacturing process Methods 0.000 description 1
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- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
- C12M29/08—Air lift
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
- C12M41/24—Heat exchange systems, e.g. heat jackets or outer envelopes inside the vessel
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Abstract
The invention discloses a medium-sized high mass transfer circulating type ventilation fermentation tank, which relates to the technical field of biological fermentation and comprises a fermentation tank body, wherein a cooling injection pipe is arranged in the fermentation tank body; a circulating cylinder is fixedly arranged in the fermentation tank body, and the top and the bottom of the circulating cylinder are both opened; the bottom of the circulating cylinder is also connected with a ventilation pipe, the first end of the ventilation pipe is arranged at the bottom in the circulating cylinder, and the second end of the ventilation pipe extends out of the fermentation tank body; the first end opening of ventilation pipe is downward to be connected with air distribution head, air distribution head's top and the first end intercommunication of ventilation pipe, air distribution head's bottom is sealed, and air distribution head's lateral wall has the mixed circulator of three-phase through the gas branch union coupling, and the feed inlet and the gas branch pipe intercommunication of the mixed circulator of three-phase, the discharge gate of the mixed circulator of three-phase is located outside the circulation section of thick bamboo. The invention aims to provide good engineering conditions for ventilation biological reaction, realize complete removal of mechanical stirring and improve the energy-saving effect in the fermentation process.
Description
Technical Field
The invention relates to the technical field of biological fermentation, in particular to a medium-sized high-mass-transfer circulating type ventilation fermentation tank.
Background
The domestic fermentation industries of antibiotics, vitamins, amino acids, organic acids and the like almost all adopt the general ventilation stirring reaction kettle technology to carry out industrial product production, and the fermentation equipment has not seen great breakthrough for decades, and the current situations of high energy consumption and low utilization rate of ventilation oxygen in the fermentation process exist all the time;
in the fermentation industry, the energy consumption (air oxygen supply, steam sterilization, stirring power consumption and circulating water cooling) accounts for 20-30% of the total product cost, wherein the stirring for fermentation accounts for 20-40% of the total energy consumption; the analysis of hydrodynamics, fermentation engineering and other aspects and antibiotic large-scale production practice are carried out on the state of the fermentation process, and a new fermentation tank structure is adopted, so that the engineering condition requirements of various biological bacteria and various fermentation products can be met, the complete stirring removal can be met, and the energy saving effect of the fermentation process can be realized by 20-40%; many fermentation varieties are suitable for medium-sized fermentation tanks (e.g. a single tank volume of 30 m)3～100m3) The method is widely popularized and implemented on medium-sized fermenters, and can realize an energy-saving result of saving 4-6 hundred million/year for the fermentation industry in anticipation according to the total domestic medium-sized fermenters accounting for 25%.
Disclosure of Invention
The invention aims to provide a medium-sized high-mass-transfer circulating type ventilation fermentation tank, which is used for solving the problems in the prior art, completely removing mechanical stirring and improving the energy-saving effect in the fermentation process.
In order to achieve the purpose, the invention provides the following scheme: the invention provides a medium-sized high mass transfer circulating type ventilation fermentation tank, which comprises a fermentation tank body, wherein a cooling injection pipe is arranged in the fermentation tank body; a circulating cylinder is fixedly arranged in the fermentation tank body, and the top and the bottom of the circulating cylinder are both opened; the bottom of the circulating cylinder is also connected with a ventilation pipe, the first end of the ventilation pipe is arranged at the bottom in the circulating cylinder, and the second end of the ventilation pipe extends out of the fermentation tank body; the first end opening of ventilation pipe is downward to be connected with air distribution head, air distribution head's top with the first end intercommunication of ventilation pipe, air distribution head's bottom is sealed, air distribution head's lateral wall has the mixed circulator of three-phase through gas branch connection, the feed inlet of the mixed circulator of three-phase with gas branch pipe intercommunication, the discharge gate of the mixed circulator of three-phase is located outside the circulating tube.
Preferably, the bottom of the circulating cylinder is fixed to the inner bottom of the fermentation tank body through a first support, and a second support is further arranged at the inner bottom of the fermentation tank body and used for supporting the three-phase mixing rotator.
Preferably, the first support is a T-shaped support, the second support is an n-shaped support, and the three-phase hybrid rotator is fixedly connected with the second support through a fixing piece.
Preferably, the bottom of the air distribution head is located above the bottom opening of the circulation cylinder.
Preferably, the lateral wall of air distribution head is provided with a plurality of gaseous branch pipe, every gaseous branch pipe all is connected with one the three-phase mixes the circulator, and is a plurality of the three-phase mixes the circulator and follows the circumference equipartition.
Preferably, each three-phase mixing rotator is provided with a plurality of discharge ports, and the discharge ports are horizontally arranged and vertically communicated with the three-phase mixing rotator.
Preferably, the three-phase mixing rotator comprises a cylindrical barrel, wherein the feed inlet is formed in one end of the barrel, the feed inlet is located in the circulating barrel and is communicated with the gas branch pipe, and the discharge outlet is formed in the other end of the barrel and extends out of the circulating barrel.
Preferably, the feed inlet and the discharge gate of three-phase mixing rotator are the toper structure, the osculum end of feed inlet and the osculum end of discharge gate all is close to the barrel sets up.
Preferably, the diameter of one end of the gas branch pipe close to the three-phase mixing rotator is gradually reduced, the diameter of the gas branch pipe is smaller than that of the feeding hole of the three-phase mixing rotator, and a gap is formed between the outer wall of the gas branch pipe and the inner wall of the feeding hole.
Compared with the prior art, the invention has the following technical effects:
the invention adopts a new fermentation tank structure, thereby meeting the achievement of completely stirring and saving 20 to 40 percent of energy in the fermentation process; but also realizes the three-pass one-reverse condition of the project of orientation, no detention zone, high gas content and high-speed rotation mixing, and fully meets the ventilation and fermentation conditions of various products of the medium-sized fermentation tank.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a schematic diagram of a medium-sized high mass transfer circulating type ventilated fermenter;
FIG. 2 is a cross-sectional view taken along line A-A of FIG. 1;
in the figure, 1 is a fermentation tank body, 2 is a circulating cylinder, 3 is a three-phase mixing rotator, 4 is a first support, 5 is a second support, 6 is an air distribution head, and 7 is a fixing piece.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.
Example one
As shown in fig. 1-2, the present embodiment provides a medium-sized high mass transfer circulating ventilation fermentation tank, which includes a fermentation tank body 1, wherein a cooling injection pipe is disposed in the fermentation tank body 1, and the fermentation tank body 1 is a conventional fermentation tank body 1, which is provided with a feeding port and a discharging port to realize feeding, discharging, and the like; the cooling injection pipe is the current device, and the fermentation heat of biological reaction process needs to adopt the heat transfer of circulating water dividing wall to take away the heat to maintain the purpose of fermentation temperature control, and the cooling injection pipe is provided with the multiunit, and along 1 inner wall of the fermentation tank system multiturn from top to bottom, hang on the brace table of 1 inner wall of the fermentation tank, let in the cooling injection pipe has the recirculated cooling water, in order to take away the fermentation heat of biological reaction process. Still fixedly in the fermentation tank body 1 be provided with a circulation section of thick bamboo 2, the top and the bottom of a circulation section of thick bamboo 2 are all opened, and the open-top is used for the material to get into, and the bottom is used for the ejection of compact.
The bottom of the circulating cylinder 2 is also connected with a vent pipe, the first end of the vent pipe is arranged at the bottom in the circulating cylinder 2, and the second end of the vent pipe extends out of the fermentation tank body 1; the first end of the ventilation pipe is downward in opening and is connected with an air distribution head 6, the top of the air distribution head 6 is communicated with the first end of the ventilation pipe, the bottom of the air distribution head 6 is closed, and the bottom of the air distribution head 6 is positioned above the opening at the bottom of the circulation cylinder 2; the lateral wall of air distribution head 6 is connected with three-phase mixing rotator 3 through the gas branch pipe that the level set up, three-phase mixing rotator 3 sets up in the bottom open-ended top of circulation section of thick bamboo 2, its feed inlet with gas branch pipe intercommunication, the discharge gate is located outside circulation section of thick bamboo 2.
In this embodiment, the bottom of the circulation cylinder 2 is fixed to the inner bottom of the fermentation tank body 1 through a first support 4, and a second support 5 is further disposed at the inner bottom of the fermentation tank body 1 and is used for fixedly supporting the three-phase mixing rotator 3. Specifically, the first support 4 is a T-shaped support, wherein the T-shaped support may include an annular reinforcing plate matched with the bottom of the circulation cylinder 2, a fixing groove may be formed in the middle of the upper surface of the reinforcing plate, the bottom of the circulation cylinder 2 is arranged in the fixing groove for fixing, a support column is arranged at the bottom of the annular reinforcing plate, and the bottom of the support column is fixed to the inner bottom wall of the fermentation tank body 1; the second support 5 may also adopt a similar T-shaped support, or an n-shaped support or other support structure meeting the working requirement, the three-phase hybrid rotator 3 is fixedly connected with the second support 5 through a fixing member 7, wherein the fixing member 7 includes a U-shaped bolt and a fixing plate, the three-phase hybrid rotator 3 is clamped on the fixing plate through the U-shaped bolt, the fixing plate is welded on the second support below, and the fixing member 7 may adopt other structures, such as a clamp, as required.
In this embodiment, the side wall of the air distribution head 6 is provided with a plurality of gas branch pipes, each gas branch pipe is connected with one three-phase mixing rotator 3, and the plurality of three-phase mixing rotators 3 are uniformly distributed along the circumference of the lower edge of the circulating cylinder 2; the sizing size and the positioning size of the circulating cylinder 2 are determined according to the actual working requirement.
In this embodiment, each three-phase mixing rotator 3 is provided with a plurality of discharge ports, preferably two discharge ports are provided in this embodiment, and the discharge ports are horizontally arranged and vertically communicated with the three-phase mixing rotator 3; the discharge ports of the plurality of three-phase mixing rotators 3 are opened in directions distributed counterclockwise as a whole.
In this embodiment, the three-phase mixing rotator 3 includes a cylindrical barrel, one end of the barrel is provided with the feed inlet, and is located in the circulation barrel 2, for with the gas branch pipe intercommunication, the other end of the barrel is provided with the discharge port, and stretches out outside the circulation barrel 2, is provided with a through hole on the barrel wall of the circulation barrel 2, and the barrel of the three-phase mixing rotator 3 is convenient to pass through. Further, the feed inlet and the discharge gate of three-phase mixing rotator 3 are the toper structure, the osculum end of feed inlet and the osculum end of discharge gate all is close to the barrel sets up.
In this embodiment, the diameter of one end of the gas branch pipe close to the three-phase mixing rotator 3 is gradually reduced, the gas branch pipe can be formed by splicing a plurality of sections of pipelines, and the plurality of sections of pipelines are connected through sealing flanges; the maximum diameter of the gas branch pipe is smaller than the minimum diameter of the feed inlet of the three-phase mixing rotator 3, and a gap is arranged between the outer wall of the gas branch pipe and the inner wall of the feed inlet, so that the material in the circulating cylinder 2 can enter the three-phase mixing rotator 3 and be discharged from the discharge outlet; wherein, one end of the gas branch pipe close to the feed inlet can be fixedly connected with the three-phase mixing rotator 3 through connecting pieces such as a bracket, a connecting rod and the like.
In the embodiment, the ventilation pipe is connected with a fan for ventilation, air introduced into the ventilation pipe is distributed under pressure to enter the three-phase mixing rotator 3, three-phase uniform mixed liquid which rotates upwards is formed outside the circulation cylinder 2 and flows to the top of the circulation cylinder 2, and is baffled to enter the circulation cylinder 2 under the action of fluid continuity characteristics and internal and external density differences to accelerate downward movement, so that fermentation liquor inside the circulation cylinder 2 carries gas and solid to move downward quickly, the external and internal flow ratio is large, and a large amount of bubbles and solid are carried downward at high speed inside the circulation cylinder 2 to form complete circulation; the high-speed mixed liquid in the circulating cylinder 2 flows downwards to push the fermentation liquid retained at the bottom of the cylinder to move to the outside of the circulating cylinder 2 and join into the overall circulation along with the carrying effect of the rising of external bubbles. In the embodiment, the whole tank realizes the three-pass one-reverse condition of the engineering of orientation, no detention zone, high gas content and high-speed rotation mixing, and fully meets the ventilation and fermentation conditions of various products of a medium-sized fermentation tank.
In the embodiment, the circulation cylinder 2 with a smaller size is adopted, and the circulation is oriented from outside to inside, so that the requirement of gas-liquid-solid three-phase circulation mixing can be met, and the requirement of tank unloading operation can be met. The inner lower part of the circulating cylinder 2 adopts a specially designed three-phase mixing rotator 3 which is transversely and rotationally arranged, a gas-liquid-solid mixture rotates along the circulating cylinder 2 and moves upwards in a diffusion manner, a high mass transfer area outside the circulating cylinder 2 maximizes the gas-liquid specific surface area, realizes a high volume oxygen transfer coefficient, and fully meets the requirements of the huge specific surface area of thalli on environmental factors and nutrients;
this embodiment forms circulation section of thick bamboo 2 extrinsic cycle upwards, interior lower circulation flow, less inside and outside through-flow ratio structure under circulation section of thick bamboo 2 inside and outside density difference, the fluid continuity characteristic effect for the inside velocity of flow that falls of circulation section of thick bamboo 2 is enough big, and the high gas content liquid solid of pulling a certain share moves downwards, and the momentum is gone down to the high velocity flow, promotes fermentation cylinder bottom and detains the fermentation broth and gushes out to the section of thick bamboo and along with the lifting and carrying effect that the bubble rises, gets into outside high mass transfer district, has ensured that the whole jar does not have the dead angle, does not have the.
The fermentation reaction kettle design realizes that the characteristic parameters of the fermentation engineering, such as circulation time, circulation liquid velocity, mixing time, gas content, volume oxygen transfer coefficient, PecLet standard number, gas-liquid-solid three-phase uniformity, dissolved oxygen rate and the like, are superior to those of the traditional medium-sized mechanical ventilation fermentation reaction kettle.
The principle and the implementation mode of the invention are explained by applying a specific example, and the description of the embodiment is only used for helping to understand the method and the core idea of the invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In view of the above, the present disclosure should not be construed as limiting the invention.
Claims (9)
1. A medium-sized high mass transfer circulating ventilation fermentation tank comprises a fermentation tank body, wherein a cooling injection pipe is arranged in the fermentation tank body; the method is characterized in that: a circulating cylinder is fixedly arranged in the fermentation tank body, and the top and the bottom of the circulating cylinder are both opened; the bottom of the circulating cylinder is also connected with a ventilation pipe, the first end of the ventilation pipe is arranged at the bottom in the circulating cylinder, and the second end of the ventilation pipe extends out of the fermentation tank body; the first end opening of ventilation pipe is downward to be connected with air distribution head, air distribution head's top with the first end intercommunication of ventilation pipe, air distribution head's bottom is sealed, air distribution head's lateral wall has the mixed circulator of three-phase through gas branch connection, the feed inlet of the mixed circulator of three-phase with gas branch pipe intercommunication, the discharge gate of the mixed circulator of three-phase is located outside the circulating tube.
2. The medium-sized high mass transfer circulating type ventilated fermenter of claim 1, wherein: the bottom of the circulating cylinder is fixed on the inner bottom of the fermentation tank body through a first support, and a second support is further arranged on the inner bottom of the fermentation tank body and used for supporting the three-phase mixing rotator.
3. The medium-sized high mass transfer circulating type ventilated fermenter of claim 2, wherein: the first support is a T-shaped support, the second support is an n-shaped support, and the three-phase hybrid rotator is fixedly connected with the second support through a fixing piece.
4. The medium-sized high mass transfer circulating type ventilated fermenter of claim 3, wherein: the bottom of the air distribution head is positioned above the bottom opening of the circulation cylinder.
5. The medium-sized high mass transfer circulating type ventilated fermenter of claim 1, wherein: the lateral wall of air distribution head is provided with a plurality ofly gaseous branch pipe, every gaseous branch pipe all is connected with one the three-phase mixing rotator is a plurality of the three-phase mixing rotator is along the circumference equipartition.
6. The medium-sized high mass transfer circulating type ventilated fermenter of claim 4, wherein: every the three-phase mixing rotator all is provided with a plurality of discharge gate, the discharge gate level sets up, and with the three-phase mixing rotator is perpendicular to be communicated.
7. The medium-sized high mass transfer circulating type ventilated fermenter of claim 1, wherein: the three-phase mixing rotator comprises a cylindrical barrel, wherein one end of the barrel is provided with the feed inlet and is positioned in the circulating barrel and communicated with the gas branch pipe, and the other end of the barrel is provided with the discharge outlet and extends out of the circulating barrel.
8. The medium-sized high mass transfer circulating type ventilated fermenter of claim 7, wherein: the feed inlet and the discharge gate of three-phase mixing rotator are the toper structure, the osculum end of feed inlet and the osculum end of discharge gate all is close to the barrel sets up.
9. The medium-sized high mass transfer circulating type ventilated fermenter of claim 8, wherein: the diameter that gas branch pipe is close to the one end of three-phase mixing circulator reduces gradually, the diameter of gas branch pipe is less than the diameter of the feed inlet of three-phase mixing circulator, the outer wall of gas branch pipe with be provided with the clearance between the inner wall of feed inlet.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111662812A (en) * | 2020-07-27 | 2020-09-15 | 风之行(上海)生物科技有限公司 | Large-scale high mass transfer circulating ventilation fermentation cylinder |
| CN113073045A (en) * | 2021-05-24 | 2021-07-06 | 风之行(上海)生物科技有限公司 | Self-mixing circulating type ventilation fermentation tank |
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