CN111658741A - A Chinese medicinal composition for treating gastritis and peptic ulcer - Google Patents
A Chinese medicinal composition for treating gastritis and peptic ulcer Download PDFInfo
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- CN111658741A CN111658741A CN202010593344.3A CN202010593344A CN111658741A CN 111658741 A CN111658741 A CN 111658741A CN 202010593344 A CN202010593344 A CN 202010593344A CN 111658741 A CN111658741 A CN 111658741A
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/57—Magnoliaceae (Magnolia family)
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Abstract
The invention discloses a traditional Chinese medicine for treating gastritis and peptic ulcer, which is prepared from the following raw material medicines in parts by weight: semen Alpiniae, radix Inulae, herba Portulacae, rhizoma Polygoni Paleachi, cortex Cinnamomi, caulis Kadsurae Longipedunculatae, fructus Caricae, herba Caryopteridis Incanae, caulis Kadsurae Longipedunculatae, herba Pileae Scriptae, radix Cudraniae Longipedunculatae, radix Rumicis Patientiae, and herba Kalimeridis. According to the traditional Chinese medicine composition for treating gastritis and peptic ulcer, the raw materials are matched and coordinated, so that the traditional Chinese medicine composition has the effects of clearing heat and removing toxicity, strengthening spleen and stomach, regulating qi to alleviate pain, stopping bleeding and removing food retention, promoting blood circulation to remove blood stasis and the like, and has a good curative effect on treating gastritis and peptic ulcer.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for treating gastritis and peptic ulcer.
Background
Gastritis is an inflammation of the gastric mucosa. There are many kinds of gastritis, such as acute and chronic gastritis, superficial gastritis, atrophic gastritis, peptic ulcer, erosive gastritis, etc. The western medicine adopts acid-inhibiting drugs or gastric motility drugs and antiviral or anti-inflammatory drugs for treatment, and treats the symptoms but not the root causes.
Peptic ulcer is a common chronic digestive tract disease, can occur in esophagus, stomach or duodenum, can also occur near a stomach-jejunum anastomotic stoma or in a Meckel diverticulum containing gastric mucosa, is easy to relapse, has long course of disease, and can be complicated with complications such as bleeding, perforation, pyloric obstruction, cachexia and the like. The western medicine uses antacid preparation, wall cell various receptor blockers, mucosa protective agent and anti-helicobacter pylori antibiotic for treatment, even needs surgical treatment, and treats the symptoms but not the root causes.
Disclosure of Invention
The invention aims to improve the defects of the prior art and provide the traditional Chinese medicine composition for treating gastritis and peptic ulcer, which can effectively improve or even eliminate the clinical symptoms of patients and has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.
Chronic gastritis belongs to the categories of epigastric pain, stuffiness syndrome and the like in traditional Chinese medicine. Gastritis has both congenital and acquired factors. Congenital factors are the relationship between the kidney and the stomach, the deficiency of the innate kidney, the lack of heat in the earth, the dysfunction of the spleen and stomach in transportation, and the formation of chronic gastritis. Modern medicine proves that chronic gastritis belongs to autoimmune injury, the blood T cell ratio is reduced due to the kidney deficiency, the body immunity function is low, and the disease is caused by the inability to eliminate antigen-antibody complexes.
The acquired factors include improper diet, impairment of middle-jiao yang, invasion of exogenous pathogenic factors due to deficiency, retention of dampness in middle-jiao, dysfunction of spleen in transport and transportation, and stomach disorder; overeating can impair the stomach and affect the spleen and stomach function; the mixed cold and heat, abnormal ascending and descending; liver qi stagnation, spleen qi deficiency or prolonged illness can enter collaterals, resulting in unsmooth blood circulation, stagnation of blood in stomach, or accumulation of stagnant phlegm; infection with Helicobacter Pylori (HP) due to pathogenic dampness, etc.
The peptic ulcer belongs to the categories of acid regurgitation and epigastric pain in traditional Chinese medicine. The traditional Chinese medicine considers that the pathogenesis of the disease is mainly due to emotional damage, overeating and the like. Worry, anger, stimulation of seven emotions, liver loss of flow and diarrhea, transverse invasion of the stomach; or spleen qi stagnation, abnormal transportation and transformation; improper diet or preference can damage the spleen and stomach; or dampness-heat obstructing the middle energizer and damaging the stomach membrane can cause ulcer. Over-working due to long-term physical or mental work, impairment of the spleen and consumption of qi, retardation of transportation and transformation, stagnation of qi and blood, and failure of the gastric membrane to grow, which are likely to cause the disease. The disease is most closely related to the spleen and kidney in the stomach, and has the characteristics of transformation from qi and blood, transformation from excess to deficiency, transformation from cold to heat, or transformation from cold to yang, transformation from heat to yin and the like in the aspect of pathogenesis transformation.
In clinical treatment of gastritis and peptic ulcer, the traditional Chinese medicine composition has the effects of clearing heat and removing toxicity, strengthening spleen and stomach, regulating qi to alleviate pain, stopping bleeding and removing food retention, and promoting blood circulation to remove blood stasis.
Based on the theory, the invention provides a traditional Chinese medicine for treating gastritis and peptic ulcer, which is prepared from the following raw material medicines in parts by weight: 3-6 parts of katsumadai seed; 5-10 parts of elecampane inula root; 10-20 parts of purslane, rhizoma polygoni paleacei, cinnamomum japonicum thunb, sargentgloryvine stem, papaya, common bluebeard herb and black tiger; 15-30 parts of glabrous sarcandra herb, cudrania root, patience dock root and Indian kalimeris herb.
In a preferred embodiment, the traditional Chinese medicine composition for treating gastritis and peptic ulcer consists of the following raw material medicines in parts by weight: 6 parts of katsumade galangal seed and 10 parts of elecampane root; 20 parts by weight of purslane, rhizoma polygoni paleacei, cinnamomum japonicum thunb, sargentgloryvine stem, papaya, common bluebeard herb and black tiger; 30 parts of glabrous sarcandra herb, cudrania root, patience dock root and Indian kalimeris herb.
Wherein, glabrous sarcandra herb: bitter, pungent and mild. It enters heart and liver meridians. For heat-clearing and blood-cooling, promoting blood circulation and removing ecchymoses, dispelling wind and dredging collaterals. The glabrous sarcandra herb has obvious antiulcer effect, strong protection and repair effect on gastric mucosa, obvious astringency effect on anabrotic ulcer and healing digestive tract ulcer in a short time, and obvious effect compared with sucralfate and Hericium erinaceus. Herba Pileae Scriptae also has effects of promoting gastric secretion and stimulating appetite.
Rhizoma polygoni paleacei: is bitter in taste; pungent taste; is cold in nature. Removing blood stasis, resolving food stagnation, and descending qi; sterilizing; stop bleeding and remove dampness. For chronic gastritis; gastric and duodenal ulcers; stagnation of food; dysentery; enteritis; edema, and the like.
Purslane: sour and cold in flavor. Clear heat and remove toxicity, remove dampness and cool blood. The purslane is rich in to-3 fatty acid, vitamin C and the like, has strong antioxidation and gastric mucosa protection effects, and has remarkable treatment effect on ulcer caused by gastric mucosa injury.
Fragrant osmanthus root: pungent, bitter and even in flavor. Regulate qi to alleviate pain, dispel wind and activate collaterals. Can be used for treating acute and chronic gastritis, and digestive tract ulcer.
Elecampane inula root: pungent, bitter and warm. Invigorating spleen; the stomach; the liver meridian. Strengthening the spleen and stomach, regulating qi to alleviate pain, stimulating the appetite and expelling parasites, regulating qi and resolving stagnation, and relieving pain and preventing miscarriage. It can be used for treating chronic gastritis, gastrointestinal dysfunction, and chronic enteritis.
Big leaf capacity sandwort: pungent in flavor and slightly warm in nature. Dispel wind and dampness, regulate qi to alleviate pain, activate blood and dissipate blood stasis. Can be used for treating acute gastroenteritis, chronic gastritis, gastric ulcer, and duodenal ulcer.
Papaya: sweet in taste; the nature is mild. Promoting digestion and promoting lactation; removing dampness and dredging collaterals; detoxicate and expel parasites. For use in dyspepsia; the stomach; duodenal ulcer pain, and the like.
And (3) kalimeris indica: pungent, bitter and cold in flavor. Clear heat and remove toxicity, dissipate blood stasis and stop bleeding, and remove food retention. For gastric ulcer, duodenal ulcer, enteritis, dysentery, etc.
Herba Caryopteridis Incanae: pungent and warm in flavor. Dispelling wind, relieving exterior syndrome, eliminating phlegm, relieving cough, dispelling blood stasis, and relieving pain. Can be used for treating gastroenteritis.
Katsumade galangal seed: pungent and warm. It enters spleen and stomach meridians. Warming middle energizer and eliminating dampness; move qi and invigorate spleen, warm stomach and arrest vomiting. Used for treating abdominal psychroalgia due to cold-dampness and yin stagnation in spleen and stomach; abdominal distention, cold pain, vomiting; diarrhea; the food cannot be eaten; halitosis is caused. It is contraindicated for patients with yin deficiency, blood deficiency and fluid deficiency, and should be used with cautions for patients without cold-dampness.
Black tiger: pungent, slightly bitter and warm. Move qi and alleviate pain, dispel wind and activate collaterals, dissipate blood stasis and relieve swelling. Can be used for treating gastric ulcer, duodenal ulcer, chronic gastritis, acute gastroenteritis, and swelling and pain due to traumatic injury.
Breaking the stone: light taste; slightly bitter; is cool in nature. Dispelling wind and dredging collaterals; clearing heat and removing dampness; detoxify and detumescence. Can be used for treating gastric ulcer and duodenal ulcer.
And (4) beef west: bitter; an acid; is cold in nature. Clearing away heat and toxic materials; hemostasis and detumescence; to moisten intestines and relax bowels. Killing pests. For hematochezia; dysentery; appendicitis, chronic enteritis, constipation; gastroduodenal bleeding, and the like.
The Chinese medicine is prepared from Chinese traditional herbal medicines, and is a Chinese medicine for effectively treating gastritis and peptic ulcer by orderly matching certain natural extracts with determined components and clear effects according to a plurality of principles of traditional Chinese medicine treatment based on syndrome differentiation and modern medicine.
The invention can be used throughout the whole process of treating gastritis and peptic ulcer, treats both principal and secondary aspect of disease and is not easy to relapse. The invention is safe and reliable, has no obvious toxic and side effects, is convenient for patients to insist on taking for a long time, has no adverse reaction after taking the medicine for many years, and tracks the blood to check normally.
The traditional Chinese medicine composition has the advantages of easily available raw materials, simple process, low cost and high efficiency, and is beneficial to pharmaceutical enterprises for medicine production and quality control; the product has low price and is easy to be accepted by patients.
The traditional Chinese medicine composition has remarkable effect of treating gastritis and peptic ulcer, and clinical experiment results show that the traditional Chinese medicine composition is used for treating gastritis and peptic ulcer, one dose of the traditional Chinese medicine composition is taken every day, the traditional Chinese medicine composition is decocted with 100 ml of water and divided into two parts, the two parts are taken in the morning and at night, one part is taken in a month as a treatment course, the traditional Chinese medicine composition takes effect in one treatment course generally, and the functions of three to six treatment courses are basically cured. The cure rate is 92 percent, and the total effective rate is 100 percent.
The invention also provides an oral preparation prepared from the traditional Chinese medicine composition for treating gastritis and peptic ulcer, wherein the oral preparation comprises oral liquid, tablets, capsules, pills and the like, preferably the dosage forms are tablets and capsules, and one dose is taken every day in the morning and at night.
The traditional Chinese medicine composition can be prepared into various dosage forms. For example, the decocted liquid medicine is sterilized and disinfected and then packaged to prepare oral liquid; or concentrating the decoction, oven drying, adding pharmaceutically acceptable adjuvants, and making into tablet, capsule, pill, etc.
The medically acceptable auxiliary materials comprise starch, dextrin, sodium carboxymethylcellulose, polyethylene glycol, calcium hydrophosphate, sodium alginate, potassium sorbate and the like.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention in any way, and it will be apparent to those skilled in the art that the above description of the present invention can be applied to various modifications, equivalent variations or modifications without departing from the spirit and scope of the present invention.
Claims (4)
1. The traditional Chinese medicine for treating gastritis and peptic ulcer is characterized by comprising the following raw material medicines in parts by weight: 3-6 parts of katsumadai seed; 5-10 parts of elecampane inula root; 10-20 parts of purslane, rhizoma polygoni paleacei, cinnamomum japonicum thunb, sargentgloryvine stem, papaya, common bluebeard herb and black tiger; 15-30 parts of glabrous sarcandra herb, cudrania root, patience dock root and Indian kalimeris herb.
2. The traditional Chinese medicine for treating gastritis and peptic ulcer according to claim 1 is characterized by comprising the following raw material medicines in parts by weight: 10 parts of elecampane inula root; 20 parts by weight of purslane, rhizoma polygoni paleacei, cinnamomum japonicum thunb, sargentgloryvine stem, papaya, common bluebeard herb and black tiger; 30 parts of glabrous sarcandra herb, hericium erinaceus, cudrania root and rhizome, patience dock root and Indian kalimeris herb.
3. An oral preparation for treating gastritis and peptic ulcer, which is prepared from the Chinese medicinal composition of any one of claims 1 or 2.
4. The oral preparation for treating gastritis and peptic ulcer according to claim 3, comprises oral liquid, tablets, capsules and pills, preferably oral liquid and tablets.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383132A (en) * | 2014-12-11 | 2015-03-04 | 吕桂兰 | Traditional Chinese medicine preparation used for treating gastric ulcer and preparation method |
| CN105943955A (en) * | 2016-06-22 | 2016-09-21 | 孙奉生 | Traditional Chinese medicine preparation for treating gastric ulcer and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383132A (en) * | 2014-12-11 | 2015-03-04 | 吕桂兰 | Traditional Chinese medicine preparation used for treating gastric ulcer and preparation method |
| CN105943955A (en) * | 2016-06-22 | 2016-09-21 | 孙奉生 | Traditional Chinese medicine preparation for treating gastric ulcer and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 周毛吉: "中藏药结合治疗胃病疗效观察", 《中国民族医药杂志》, vol. 9, no. 1, pages 17 * |
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