CN111655868A - 恶性淋巴瘤标志物及其应用 - Google Patents

恶性淋巴瘤标志物及其应用 Download PDF

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Publication number
CN111655868A
CN111655868A CN201880083693.1A CN201880083693A CN111655868A CN 111655868 A CN111655868 A CN 111655868A CN 201880083693 A CN201880083693 A CN 201880083693A CN 111655868 A CN111655868 A CN 111655868A
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China
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mutation
sequencing
malignant lymphoma
probe
candidate
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CN201880083693.1A
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English (en)
Inventor
叶晓飞
苏红
潘嫱
刘栋兵
任伟成
吴逵
朱师达
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BGI Shenzhen Co Ltd
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BGI Shenzhen Co Ltd
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Publication of CN111655868A publication Critical patent/CN111655868A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

提供了一种恶性淋巴瘤标志物，该恶性淋巴瘤的标志物包括AICDA、AKT1等共计212个基因。还提供了该标志物在基因测序以及医学检测领域的应用。

Description

PCT国内申请，说明书已公开。

Claims (30)

  1. PCT国内申请，权利要求书已公开。
CN201880083693.1A 2018-03-14 2018-03-14 恶性淋巴瘤标志物及其应用 Pending CN111655868A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2018/079061 WO2019173991A1 (zh) 2018-03-14 2018-03-14 恶性淋巴瘤标志物及其应用

Publications (1)

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CN111655868A true CN111655868A (zh) 2020-09-11

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CN201880083693.1A Pending CN111655868A (zh) 2018-03-14 2018-03-14 恶性淋巴瘤标志物及其应用

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CN (1) CN111655868A (zh)
WO (1) WO2019173991A1 (zh)

Citations (12)

* Cited by examiner, † Cited by third party
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WO2006112483A1 (ja) * 2005-04-19 2006-10-26 Aichi Prefecture びまん性大細胞型ｂ細胞リンパ腫の病型の診断方法及び予後診断の方法
US20080004208A1 (en) * 2004-12-03 2008-01-03 Aichi Prefecture Methods for Diagnosis and Prognosis of Malignant Lymphoma
CN101184772A (zh) * 2005-03-30 2008-05-21 金弦起 人类原癌基因及其编码的蛋白质
WO2009082856A1 (fr) * 2007-12-28 2009-07-09 Ruijin Hospital Affiliated To The Shanghai Jiao Tong University Medical School Marqueur moléculaire utilisé pour le pronostic d'un lymphome diffus à gros lymphocytes b
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US20110159492A1 (en) * 2008-06-04 2011-06-30 Rimsza Lisa M Diffuse Large B-Cell Lymphoma Markers and Uses Therefore
CN102808019A (zh) * 2011-06-03 2012-12-05 复旦大学附属肿瘤医院 弥漫性大b细胞淋巴瘤分子标记物检测方法及其应用
US20140045915A1 (en) * 2010-08-31 2014-02-13 The General Hospital Corporation Cancer-related biological materials in microvesicles
JP2016080672A (ja) * 2014-10-17 2016-05-16 勇 廣▲瀬▼ 悪性リンパ腫の検出法
CN105603052A (zh) * 2014-11-11 2016-05-25 武汉华大医学检验所有限公司 探针及其用途
CN105624272A (zh) * 2014-10-29 2016-06-01 深圳华大基因科技有限公司 基因组预定区域核酸测序文库的构建方法及装置
CN105779572A (zh) * 2014-12-22 2016-07-20 深圳华大基因研究院 肿瘤易感基因目标序列捕获芯片、方法及突变检测方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101470112A (zh) * 2007-12-28 2009-07-01 上海交通大学医学院附属瑞金医院 弥漫性大b细胞淋巴瘤治疗指导和预后判断的分子标志物
CN101470119A (zh) * 2007-12-28 2009-07-01 上海交通大学医学院附属瑞金医院 弥漫性大b细胞淋巴瘤分子病理分型方法及应用
US8592156B2 (en) * 2011-08-08 2013-11-26 Roche Molecular Systems, Inc. Predicting response to anti-CD20 therapy in DLBCL patients

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080004208A1 (en) * 2004-12-03 2008-01-03 Aichi Prefecture Methods for Diagnosis and Prognosis of Malignant Lymphoma
CN101184772A (zh) * 2005-03-30 2008-05-21 金弦起 人类原癌基因及其编码的蛋白质
WO2006112483A1 (ja) * 2005-04-19 2006-10-26 Aichi Prefecture びまん性大細胞型ｂ細胞リンパ腫の病型の診断方法及び予後診断の方法
WO2009082856A1 (fr) * 2007-12-28 2009-07-09 Ruijin Hospital Affiliated To The Shanghai Jiao Tong University Medical School Marqueur moléculaire utilisé pour le pronostic d'un lymphome diffus à gros lymphocytes b
US20110159492A1 (en) * 2008-06-04 2011-06-30 Rimsza Lisa M Diffuse Large B-Cell Lymphoma Markers and Uses Therefore
US20140045915A1 (en) * 2010-08-31 2014-02-13 The General Hospital Corporation Cancer-related biological materials in microvesicles
CN101968491A (zh) * 2010-09-29 2011-02-09 上海生物芯片有限公司 弥漫性大b细胞淋巴瘤分子病理分型方法及试剂盒和应用
CN102808019A (zh) * 2011-06-03 2012-12-05 复旦大学附属肿瘤医院 弥漫性大b细胞淋巴瘤分子标记物检测方法及其应用
JP2016080672A (ja) * 2014-10-17 2016-05-16 勇 廣▲瀬▼ 悪性リンパ腫の検出法
CN105624272A (zh) * 2014-10-29 2016-06-01 深圳华大基因科技有限公司 基因组预定区域核酸测序文库的构建方法及装置
CN105603052A (zh) * 2014-11-11 2016-05-25 武汉华大医学检验所有限公司 探针及其用途
CN105779572A (zh) * 2014-12-22 2016-07-20 深圳华大基因研究院 肿瘤易感基因目标序列捕获芯片、方法及突变检测方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MARA COMPAGNO 等: "Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma" *
崔蕴博 等: "弥漫性大B 细胞淋巴瘤发病分子遗传机制的研究进展" *

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