CN111630389B - 牙周炎诊断方法、用途和试剂盒 - Google Patents

牙周炎诊断方法、用途和试剂盒 Download PDF

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Publication number
CN111630389B
CN111630389B CN201980008597.5A CN201980008597A CN111630389B CN 111630389 B CN111630389 B CN 111630389B CN 201980008597 A CN201980008597 A CN 201980008597A CN 111630389 B CN111630389 B CN 111630389B
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Prior art keywords
periodontitis
protein
concentration
light chain
free light
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CN201980008597.5A
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Chinese (zh)
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CN111630389A (zh
Inventor
G·库伊杰曼
A·H·里迈勒
C·格拉斯
M·K·J·德加格
I·L·C·察柏尔
M·M·格兰特
P·普雷肖
J·J·泰洛尔
M·A·范哈特斯卡姆普
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/18—Dental and oral disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CN201980008597.5A 2018-01-16 2019-01-09 牙周炎诊断方法、用途和试剂盒 Active CN111630389B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18151839.0A EP3511716A1 (en) 2018-01-16 2018-01-16 Periodontitis diagnostic methods, uses and kits
EP18151839.0 2018-01-16
PCT/EP2019/050364 WO2019141547A1 (en) 2018-01-16 2019-01-09 Periodontitis diagnostic methods, uses and kits

Publications (2)

Publication Number Publication Date
CN111630389A CN111630389A (zh) 2020-09-04
CN111630389B true CN111630389B (zh) 2025-04-22

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CN201980008597.5A Active CN111630389B (zh) 2018-01-16 2019-01-09 牙周炎诊断方法、用途和试剂盒

Country Status (7)

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US (1) US20210063412A1 (https=)
EP (2) EP3511716A1 (https=)
JP (2) JP7330983B2 (https=)
CN (1) CN111630389B (https=)
CA (1) CA3088339A1 (https=)
RU (1) RU2020127365A (https=)
WO (1) WO2019141547A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3553523A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Diagnostics of mild or advanced periodontitis
EP3553520A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Methods, uses and kits for monitoring or predicting response to periodontal disease treatment
WO2022096893A1 (en) 2020-11-04 2022-05-12 The University Of Birmingham Device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104620110A (zh) * 2012-09-10 2015-05-13 皇家飞利浦有限公司 使用ft-icr-ms/ms的对于牙龈炎和牙周炎的生物标志物的唾液蛋白质组分析

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Publication number Priority date Publication date Assignee Title
US7179606B2 (en) * 2001-11-23 2007-02-20 Syn X Pharma, Inc. IG heavy chain, IG kappa, IG lambda biopolymer markers predictive of Alzheimer's disease
CN101523218B (zh) * 2006-09-29 2014-07-09 霍夫曼-拉罗奇有限公司 评估类风湿性关节炎患者疾病进展的风险
US8728744B2 (en) 2007-10-26 2014-05-20 The Regents Of The University Of California Salivary protein biomarkers for human oral cancer
US8889364B2 (en) * 2009-05-14 2014-11-18 The Chancellor, Masters And Scholars Of The University Of Oxford Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
WO2010151789A1 (en) * 2009-06-25 2010-12-29 The Regents Of The University Of California Salivary transcriptomic and microbial biomarkers for pancreatic cancer
WO2011133770A2 (en) * 2010-04-21 2011-10-27 Board Of Regents Of The University Of Texas System Salivary protein markers for detection of breast cancer
JP5869323B2 (ja) 2011-12-01 2016-02-24 花王株式会社 歯周病マーカー
US10393749B2 (en) * 2013-12-11 2019-08-27 Shiseido Company, Ltd. Marker for early diagnosis of kidney failure
US10703813B2 (en) * 2014-12-19 2020-07-07 Universite De Nantes Anti IL-34 antibodies
GB201708262D0 (en) * 2017-05-23 2017-07-05 Binding Site Group Ltd Assay for plasma cell associated disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104620110A (zh) * 2012-09-10 2015-05-13 皇家飞利浦有限公司 使用ft-icr-ms/ms的对于牙龈炎和牙周炎的生物标志物的唾液蛋白质组分析

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Jennifer L J Heaney等.Salivary immunoglobulin free light chains: reference ranges and responses to exercise in young and older adults.Exerc Immunol Rev..2016,第22卷第28-41页. *
Salivary immunoglobulin free light chains: reference ranges and responses to exercise in young and older adults;Jennifer L J Heaney等;Exerc Immunol Rev.;第22卷;第28-41页 *

Also Published As

Publication number Publication date
RU2020127365A3 (https=) 2022-04-08
JP2023134563A (ja) 2023-09-27
CN111630389A (zh) 2020-09-04
EP3740759A1 (en) 2020-11-25
JP7330983B2 (ja) 2023-08-22
RU2020127365A (ru) 2022-02-17
JP2021510815A (ja) 2021-04-30
WO2019141547A1 (en) 2019-07-25
EP3740759C0 (en) 2025-04-30
CA3088339A1 (en) 2019-07-25
EP3511716A1 (en) 2019-07-17
US20210063412A1 (en) 2021-03-04
EP3740759B1 (en) 2025-04-30

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