CN111617225A - A Chinese medicinal preparation for treating cough diseases, and its preparation method - Google Patents

A Chinese medicinal preparation for treating cough diseases, and its preparation method Download PDF

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Publication number
CN111617225A
CN111617225A CN202010660177.XA CN202010660177A CN111617225A CN 111617225 A CN111617225 A CN 111617225A CN 202010660177 A CN202010660177 A CN 202010660177A CN 111617225 A CN111617225 A CN 111617225A
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parts
juice
preparation
traditional chinese
cough
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姚玉兰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention discloses a traditional Chinese medicine preparation for treating cough diseases and a preparation method thereof, wherein the active ingredients of the traditional Chinese medicine preparation are prepared from the following traditional Chinese medicines in parts by weight: 55-65 parts of acid pomegranate juice, 20-30 parts of sophora flower honey, 3-4 parts of evanescent shellfish, 6 parts of American ginseng, 1 part of ginger juice and 1 part of snow pear juice. The traditional Chinese medicine preparation for treating cough diseases is prepared from pure traditional Chinese medicines, has a simple preparation method, can be used for treating diseases such as wind-cold cough, asthma, emphysema and the like, has good taste and no side effect, and has a certain effect on enhancing human immunity; snow pear has the functions of moistening lung, clearing away dryness, relieving cough, reducing phlegm, nourishing blood and promoting granulation.

Description

A Chinese medicinal preparation for treating cough diseases, and its preparation method
Technical Field
The invention relates to the technical field of medicaments for treating cough diseases, in particular to a traditional Chinese medicine preparation for treating cough diseases and a preparation method thereof.
Background
Cough is a protective breathing reflex action of the human body. Cough occurs because when foreign substances, irritant gases, airway secretions and the like irritate receptors in the airway mucosa, impulses are transmitted to the medullary cough center through afferent nerve fibers, causing cough. Cough is caused by many reasons, and except respiratory organs such as nose, pharynx, larynx, trachea, bronchus, lung and pleura, vagus nerves of internal organs such as ear, meninges, heart, esophagus and stomach are stimulated and transmitted into cough center to cause cough. Cough is the main symptom of respiratory system diseases, such as dry cough with little or no phlegm, which is often seen in the early stages of acute pharyngolaryngitis and bronchitis; acute and sudden cough often occurs in the intrabronchial foreign body; chronic cough is often seen in chronic bronchitis, pulmonary tuberculosis, etc. The adverse effect of cough is to spread the pathological changes of the trachea to the adjacent small bronchi, which aggravates the disease. In addition, persistent and severe cough can affect rest, is prone to physical exertion, and can cause destruction of alveolar wall elastic tissue, inducing emphysema. The cough of children is endless vexation to parents, and the medicine for treating cough is spread all over the ground, can be difficult to stop children's cough, influences children and parents ' rest, and some coughs have all been spitted out the meal of eating, and father mother's heart lets children's sound of cough tightly, and medication, food therapy, physiotherapy, atomizing treatment, the folk prescription uses one more, and neither can be inexperienced, and the infant cough that can't cure for a long time puzzles father mother. Parents are most concerned about how to relieve cough.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine preparation for treating cough diseases and a preparation method thereof, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a traditional Chinese medicine preparation for treating cough diseases is prepared from the following traditional Chinese medicines as active ingredients in parts by weight: 55-65 parts of acid pomegranate juice, 20-30 parts of sophora flower honey, 3-4 parts of evanescent shellfish, 6 parts of American ginseng, 1 part of ginger juice and 1 part of snow pear juice. The active ingredients of the Chinese medicinal preparation are prepared from the following Chinese medicaments in part by weight: 60 parts of acid pomegranate juice, 25 parts of sophora flower honey, 1.5 parts of evanescent shellfish, 6 parts of American ginseng, 1 part of ginger juice and 1 part of snow pear juice. The invention also discloses a preparation method of the traditional Chinese medicine preparation for treating cough diseases, which comprises the following steps: 1) peeling fructus Punicae Granati, and squeezing to obtain juice; 2) adding 20-30 parts of sophora flower honey, 3-4 parts of evanescent shellfish, 6 parts of American ginseng, 1 part of ginger juice and 1 part of snow pear juice into 55-65 parts of acid pomegranate juice, decocting until boiling for three times, cooling, filtering, and bottling the filtrate.
The invention has the following beneficial effects: in the invention, the acid pomegranate juice contains rich antioxidants with anti-inflammatory effect, the sophora flower honey has lung clearing effect and has a considerable effect on respiratory system diseases, the hybridum has the effects of moistening lung and resolving masses, relieving cough and reducing sputum, and the American ginseng has the function of maintaining balance in vivo and recovering body functions to be normal. The traditional Chinese medicine composition disclosed by the invention is prepared from multiple traditional Chinese medicines, is scientific in compatibility, has the effects of dispelling wind-cold, diminishing inflammation and moistening lung, and has a remarkable effect of treating cough diseases. Especially, the cure rate of people with the diseases of cough due to wind-cold evil, asthma and emphysema is high.
The usage and dosage of the invention are as follows: it is administered orally at an empty stomach 20 ml before meals in the morning and evening every day, and spicy taste is prohibited during administration.
The medicine prepared by using the pomegranate acid is mainly used for treating asthma, cough, whooping cough, pharyngitis, nasosinusitis, pneumonia, chronic bronchitis, emphysema and tracheitis, and has the efficacy of reducing blood pressure, because the medicine is an acid medicine and has the function of dissolving blood vessels;
the ginger juice is added into the traditional Chinese medicine and pharmacy, and has the effects of dispersing, preventing vomiting, relieving cough and the like; snow pear has the functions of moistening lung, clearing dryness, relieving cough, reducing phlegm, nourishing blood and promoting granulation, so that the snow pear has good effects on dry throat, itching, pain, hoarseness, thick phlegm, constipation, dark urine and phlegm elimination of patients suffering from acute tracheitis and upper respiratory tract infection.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides a technical scheme that: a Chinese medicinal preparation for treating cough diseases and a preparation method thereof,
example 11) peeling and juicing pomegranate; 2) 150 g of sophora flower honey, 3g of honey, 6g of American ginseng, 1 g of ginger juice and 1 g of snow pear juice are added into 350 g of acid pomegranate juice, the mixture is decocted for three times, cooled and filtered, and the filtrate is bottled.
Example 2 the following example was prepared as described in example 1: 330 g of acid pomegranate juice, 180g of sophora flower honey, 3g of vanishing shellfish, 6g of American ginseng, 1 g of ginger juice and 1 g of snow pear juice. Example 3
The following examples were prepared as described in example 1: 360 g of acid pomegranate juice, 160g of sophora flower honey, 3g of vanishing shellfish, 6g of American ginseng, 1 g of ginger juice and 1 g of snow pear juice.
Example 4
The following examples were prepared as described in example 1: 380 g of acid pomegranate juice, 140g of sophora flower honey, 4g of vanishing shellfish, 6g of American ginseng, 1 g of ginger juice and 1 g of snow pear juice.
Example 5
The following examples were prepared as described in example 1: 4g of vanishing shellfish, 6g of American ginseng, 1 g of ginger juice and 1 g of snow pear juice. Example 6
In the curative effect test example, 65 patients with 4-14 years old who meet the diagnosis standard of moderate and severe asthma are selected, 36 patients are divided into a group A, 20 milliliters of the traditional Chinese medicine preparation prepared by the embodiment 1 of the invention are used respectively in the morning and at night, 29 patients are selected in a group B, acute bronchitis cough syrup is used for the treatment in the morning and at night, and the treatment course is 8 weeks. The asthma diary and the peak flow meter are provided uniformly, a specialist doctor is responsible for teaching the teacher to record the asthma diary, and the operating method of the quantitative aerosol inhalation device and the peak flow meter is used. Follow-up visits are made 1, 2, 4, 6 and 8 weeks after treatment, and relevant record items, clinical effects and adverse reactions are observed. As a result, the scores of the two groups of symptoms and the PEF values in the morning and at night are remarkably improved, the dosage of the short-acting beta 2 agonist is remarkably reduced, and the curative effect of A, B two groups of children patients is self-curative
The evaluation shows that the effective rate reaches 96.97 percent and 96.3 percent respectively. A. The comprehensive curative effect evaluation of the two groups B shows that the significant efficiency is 84.9 percent and 81.5 percent, and no other adverse reactions are seen except that 1 subjective sore throat occurs for two days and 1 transient hoarseness occurs. The clinical test shows that the traditional Chinese medicine preparation has obvious curative effect on asthma of medium and severe children over 4 years old, is safe to use, can simplify the asthma treatment scheme, is convenient for patients and increases compliance.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (3)

1. A traditional Chinese medicine preparation for treating cough diseases is characterized in that: the active ingredients of the Chinese medicinal preparation are prepared from the following Chinese medicaments in part by weight: 55-65 parts of acid pomegranate juice, 20-30 parts of sophora flower honey, 3-4 parts of evanescent shellfish, 6 parts of American ginseng, 1 part of ginger juice and 1 part of snow pear juice.
2. The traditional Chinese medicine preparation for treating cough diseases according to claim 1, which is characterized in that: the active ingredients of the Chinese medicinal preparation are prepared from the following Chinese medicaments in part by weight: 60 parts of acid pomegranate juice, 25 parts of sophora flower honey, 1.5 parts of evanescent shellfish, 6 parts of American ginseng, 1 part of ginger juice and 1 part of snow pear juice.
3. The method for preparing a Chinese medicinal preparation for treating cough diseases according to claim 2, wherein the method comprises the following steps: the preparation method comprises the following steps: 1) peeling fructus Punicae Granati, and squeezing to obtain juice; 2) adding 20-30 parts of sophora flower honey, 3-4 parts of evanescent shellfish, 6 parts of American ginseng, 1 part of ginger juice and 1 part of snow pear juice into 55-65 parts of acid pomegranate juice, decocting until boiling for three times, cooling, filtering, and bottling the filtrate.
CN202010660177.XA 2020-07-10 2020-07-10 A Chinese medicinal preparation for treating cough diseases, and its preparation method Pending CN111617225A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1628707A (en) * 2003-12-16 2005-06-22 孙家盛 Cough stopping liquor
CN101342306A (en) * 2008-08-27 2009-01-14 姚玉兰 Traditional Chinese medicine preparation for treating cough diseases and preparation method thereof
CN104587429A (en) * 2015-01-08 2015-05-06 吉林省北域西洋参研究有限公司 Ginger juice and honey impregnated American ginseng preparation and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1628707A (en) * 2003-12-16 2005-06-22 孙家盛 Cough stopping liquor
CN101342306A (en) * 2008-08-27 2009-01-14 姚玉兰 Traditional Chinese medicine preparation for treating cough diseases and preparation method thereof
CN104587429A (en) * 2015-01-08 2015-05-06 吉林省北域西洋参研究有限公司 Ginger juice and honey impregnated American ginseng preparation and preparation method thereof

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Application publication date: 20200904