CN111592959A - Tonic three-penis wine and extraction method thereof - Google Patents

Tonic three-penis wine and extraction method thereof Download PDF

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CN111592959A
CN111592959A CN202010423788.2A CN202010423788A CN111592959A CN 111592959 A CN111592959 A CN 111592959A CN 202010423788 A CN202010423788 A CN 202010423788A CN 111592959 A CN111592959 A CN 111592959A
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wine
ingredients
tonic
liquor
extraction
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刘传文
仇政芳
张咏梅
张衡伟
魏玮
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Yantai Central Asia Healthcare Wine Co ltd
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Yantai Central Asia Healthcare Wine Co ltd
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Abstract

The invention provides a tonic three-animal whip wine and an extraction method thereof, wherein the tonic three-animal whip wine is prepared from the following ingredients: each 10000L of ingredients comprise 0.2-0.7 kg of seal penis, 0.5-1.2 kg of deer penis, 4.5-7 kg of dog penis, 9-12 kg of ginseng, 8-10 kg of cinnamon, 18-20 kg of medlar, 20-22 kg of tuckahoe, 25-35 kg of yam, 2-6 kg of pepper, 3-5 kg of fennel, fen-flavor liquor, distilled grape wine, 15-25L of yellow wine, 500-600 kg of white granulated sugar and 6-10L of caramel color. Weighing the ingredients, and then processing the obtained ingredients through pretreatment, extraction, wine preparation, freezing and filtration; the pretreatment comprises crushing the obtained ingredients; the extraction comprises the steps of soaking the crushed ingredients in fen-flavor liquor, performing multi-stage countercurrent percolation extraction and obtaining an extracting solution; the wine blending comprises adding Chinese liquor and yellow wine into the extract. The nourishing nutritional wine provided by the invention adopts a special extraction process, extracts more abundant nutritional components, and remarkably improves the immunity of animals.

Description

Tonic three-penis wine and extraction method thereof
Technical Field
The invention belongs to the field of food wine and an extraction method, and particularly relates to nourishing three-penis wine and an extraction method thereof.
Background
The Chinese herbal medicine wine is a nourishing drink integrating traditional Chinese medicines for building up the body and wine, takes alcohol as a good solvent of the traditional Chinese medicine components, and the traditional Chinese medicines and the alcohol exert effects in a synergistic manner, so that the curative effect of the traditional Chinese medicines is improved. The preparation of Chinese herbal medicine wine is to soak Chinese herbal medicine in wine for some time to dissolve the effective components of the Chinese herbal medicine in the wine, and then to filter and eliminate dregs before drinking.
The existing extraction process of Chinese herbal medicine wine is that the Chinese herbal medicines are directly soaked in the koji wine or alcohol for a period of time, water is added to reduce the alcohol content, and a proper amount of granulated sugar and auxiliary materials are added to make the wine have moderate taste, but the extraction of the nutrient components in the wine solution is too little, and the nourishing performance of the wine is greatly reduced. Patent CN103060158A discloses a kidney-tonifying three-penis wine, which is prepared from penis cervi, testis Et penis bovis seu Bubali, penis canitis, fructus Lycii, Poria, cortex Cinnamomi, radix Puerariae, and herba Menthae by soaking in 500 g of 50 ° Chinese liquor for 720 hr, filtering, and blending with sweet yellow wine and water. According to the method, the Chinese herbal medicines are soaked in the white spirit to extract the active ingredients of the Chinese herbal medicines, however, the extracted ingredients of the obtained Chinese herbal medicines are very limited, a large amount of valuable active ingredients still remain in the filtered residues, the nutrition and nourishing performance is greatly reduced, and the obtained three-animal whip wine has the technical problems of being too turbid, uncomfortable in taste and the like.
In order to solve the above problems, research and development personnel for medicines are continuously developing various tonic wines with high nutrient contents.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides the nourishing three-animal penes wine and the extraction method thereof, the extracted useful components of the nourishing three-animal penes wine have high extraction rate and unique taste, and the clarity meets the sensory requirements, namely, the wine is clear and transparent and has no sediment or suspended matters.
The first aspect of the invention provides a nourishing three-penis wine, which is prepared from the following ingredients: each 10000L of ingredients comprise 0.2-0.7 kg of seal penis, 0.5-1.2 kg of deer penis, 4.5-7 kg of dog penis, 9-12 kg of ginseng, 8-10 kg of cinnamon, 18-20 kg of medlar, 20-22 kg of tuckahoe, 25-35 kg of yam, 2-6 kg of pepper, 3-5 kg of fennel, fen-flavor liquor, distilled grape wine, 15-25L of yellow wine, 500-600 kg of white granulated sugar and 6-10L of caramel color. According to the technical scheme, distilled liquor and fermented liquor are used as liquor bases, edible and medicinal animal and plant and food additives are added, blending and mixing are carried out, the original liquor base style of the alcoholic beverage is changed, and the requirements of national standard GB/T27588-2011 are met.
Preferably, the nourishing three-whip wine has the alcoholic strength of 34-36% vol and the total sugar of 54-66 g/L. By adopting the technical scheme, the alcohol content and the total sugar content of the nourishing three-animal-penis wine are adjusted through a large number of experiments and the requirements of nutrition and nourishing of human bodies, and the taste of the nourishing three-animal-penis wine is adjusted to meet the requirement of the good taste of the food wine.
Preferably, for the nourishing three-animal penes wine, the dosage of the fen-flavor liquor is 10000L multiplied by N% multiplied by 90% ÷ M, and the dosage of the grape distilled liquor is 10000L multiplied by N% multiplied by 10% ÷ G; wherein M is the alcohol content of the fen-flavor liquor, N is the numerical value of the alcohol content of the tonic three-whip liquor, and G is the alcohol content of the grape distilled liquor. The wine base with the proportion realizes the wine flavor of the nourishing three-animal penes wine, and the nourishing three-animal penes wine has unique taste.
The second aspect of the invention provides an extraction method of nourishing three-animal penes wine, weighing the above ingredients, and then processing the obtained ingredients through pretreatment, extraction, wine preparation, freezing and filtration; the pretreatment comprises crushing the obtained ingredients; the extraction comprises the steps of soaking the crushed ingredients in fen-flavor liquor, performing multi-stage countercurrent percolation extraction and obtaining an extracting solution; the wine blending comprises adding Chinese liquor, yellow wine and grape distilled liquor into the extracting solution. By adopting the technical scheme and the novel extraction process, the useful components in the animal and plant medicinal materials are fully extracted, the content of total solids in the extracting solution is improved, and the content of dry extract in the prepared wine is improved.
Preferably, for the extraction method, the weight of the fen-flavor liquor is 45-49 times of the weight of the crushed ingredients. By adopting the technical scheme, the full amount of the fen-flavor liquor in the liquor is nearly equal to the full amount of the fen-flavor liquor in the liquor prepared by extracting and adding the fen-flavor liquor, so that the full extraction of useful components is further ensured.
Preferably, for the extraction method as described above, the extraction comprises: the height of the ingredients of the fen-flavor liquor for soaking is not less than 15 cm. By adopting the technical scheme, the crushed ingredients can be completely soaked in the fen-flavor liquor in the soaking process.
Preferably, for the extraction method, the speed of the percolation is 140 +/-10L/hr, and the temperature of the percolation is 35-40 ℃. By adopting the technical scheme, the useful components in the ingredients are extracted to the maximum extent through percolation in the temperature range; the percolation speed (percolation speed of 5-stage counter-current, average about 28 + -2L/hr per tank) is used for percolation, so that the useful components are completely extracted before the solvent is used up.
Preferably, for the extraction method as described above, said freezing comprises: the freezing temperature is-6.5-7.5 deg.C, and the freezing time is not less than 24 hr. The adoption of the adjustment of the freezing temperature and the freezing time ensures that the clarity of the wine reaches the sensory requirement after the wine is filtered by the diatomite filter and the plate and frame filter, namely the wine is clear and transparent and has no sediment or suspended matters.
The third aspect of the invention provides application of the nourishing three-penis wine in the fields of medical treatment and beauty.
The fourth aspect of the invention provides application of the nourishing three-animal penes wine prepared by the extraction method in the fields of medical treatment and beauty.
The beneficial effects created by the invention are as follows:
the nourishing three-animal penes wine prepared by the invention adopts a new extraction process, so that the active ingredients in the medicinal materials are extracted more completely, the extraction rate of useful ingredients is high, the taste is unique, the clarity meets the sensory requirement, namely, the wine is clear and transparent, and has no precipitate or suspended matters.
Detailed Description
The experimental methods of the following examples, which are not specified under specific conditions, are generally determined according to national standards. If there is no corresponding national standard, it is carried out according to the usual international standards, to the conventional conditions or to the conditions recommended by the manufacturer.
As used herein, "comprising," having, "or" including "includes" comprising, "" consisting essentially of … …, "" consisting essentially of … …, "and" consisting of … …; "consisting essentially of … …", "consisting essentially of … …", and "consisting of … …" are subordinate concepts of "comprising", "having", or "including".
The features mentioned with reference to the invention or the features mentioned with reference to the embodiments can be combined. All the features disclosed in this specification may be combined in any combination, and each feature disclosed in this specification may be replaced by alternative features serving the same, equivalent or similar purpose. Thus, unless expressly stated otherwise, the features disclosed are merely generic examples of equivalent or similar features.
The "ranges" disclosed herein are in the form of lower and upper limits. There may be one or more lower limits, and one or more upper limits, respectively. The given range is defined by the selection of a lower limit and an upper limit. The selected lower and upper limits define the boundaries of the particular range. All ranges that can be defined in this manner are inclusive and combinable, i.e., any lower limit can be combined with any upper limit to form a range. For example, the ranges of 2000-. Furthermore, if the minimum range values 1 and 2 are listed, and if the maximum range values 3, 4, and 5 are listed, the following ranges are all contemplated: 1-3, 1-4, 1-5, 2-3, 2-4 and 2-5.
In the present invention, unless otherwise stated, the numerical range "a-b" represents a shorthand representation of any combination of real numbers between a and b, where a and b are both real numbers. For example, a numerical range of "0 to 5" indicates that all real numbers between "0 to 5" have been listed herein, and "0 to 5" is only a shorthand representation of the combination of these numbers.
The term "a" or "an" as used herein means "at least one" if not otherwise specified.
In the present invention, all embodiments and preferred embodiments mentioned herein may be combined with each other to form a new technical solution, if not specifically stated.
In the present invention, all the technical features mentioned herein and preferred features may be combined with each other to form a new technical solution, if not specifically stated.
In the present invention, all the steps mentioned herein may be performed sequentially or randomly, if not specifically stated, but preferably sequentially. For example, the method comprises steps (a) and (b), meaning that the method may comprise steps (a) and (b) performed sequentially, and may also comprise steps (b) and (a) performed sequentially. For example, reference to the process further comprising step (c) means that step (c) may be added to the process in any order, for example, the process may comprise steps (a), (b) and (c), may also comprise steps (a), (c) and (b), may also comprise steps (c), (a) and (b), etc.
In the present invention, specific numerical values and specific substances in the examples herein may be combined with other features of the parts described herein, if not specifically stated. For example, where the temperature of the reaction is mentioned in the description section as being 45-105 ℃ and the temperature of the reaction is mentioned in the examples as being 60 ℃, it is to be understood that the range of 45-60 ℃ or the range of 60-105 ℃ has been specifically disclosed herein and that the other features of the description section can be combined to form new embodiments.
In the present invention, all embodiments and preferred embodiments mentioned herein may be combined with each other to form a new technical solution, if not specifically stated.
In the present invention, all the technical features mentioned herein and preferred features may be combined with each other to form a new technical solution, if not specifically stated.
In order to make the technical means, the original characteristics, the achieved purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments, but the invention includes but is not limited to the embodiments.
Example 1 Tonic Sanbian wine and extraction method thereof
This example describes a tonic three-whip wine and its extraction method, and the formulation of the tonic three-whip wine is shown in table 1 below.
TABLE 1 Tonic Sanbian wine formula (10000L of each ingredient)
Figure BDA0002497915420000041
Figure BDA0002497915420000051
The addition amount of the fen-flavor liquor and the grape distilled liquor is added according to the following formula:
the volume calculation formula of the fen-flavor liquor is as follows: 10000L multiplied by 35.0% multiplied by 90% divided by the alcohol content of the fen-flavor liquor.
The calculation formula of the total volume of the added grape distilled wine is as follows: 10000L 35.0% × 10% ÷ alcohol content of the wine.
All the medicinal materials in the formula are respectively selected to remove impurities and foreign matters according to different requirements. The processing is carried out according to the pharmacopoeia of the people's republic of China and the processing specifications of the traditional Chinese medicines in Shandong province (2002 edition).
The method comprises the following steps: pretreatment of
(A) Ginseng radix, cortex Cinnamomi, fructus Lycii, Poria, rhizoma Dioscoreae, fructus Zanthoxyli, and fructus Foeniculi to remove impurities and non-medicinal parts (conventional method, specifically, see the pharmacopoeia of people's republic of China 2015 edition and the processing Specification of decoction pieces of Chinese medicinal materials in Shandong province 2012 edition).
(B) The fur seal penis, deer penis and testis et penis Canitis are processed by the processing technique after removing impurities and non-medicinal parts.
(C) Preparing materials: the finished product 10000L is proportioned, and the pretreated pure medicinal materials with the specified weight in the formula table are weighed.
(D) Crushing: the materials obtained in the batching procedure are crushed into coarse slag by a crusher, and the coarse slag passes through a No. one sieve (10 meshes) according to a medicine sieve used in the pharmacopoeia of the people's republic of China 2015 edition, but is mixed with powder which can pass through a No. three sieve (50 meshes) and does not exceed 20%.
Step two: extraction of
1. Feeding: and (4) putting the medicinal materials processed in the step one into an extraction tank.
2. Extraction: soaking each pot of crude drug residues in 60-65% fen-flavor liquor for 24 hours (at the soaking temperature of 35-40 ℃), wherein the dosage of the soaked fen-flavor liquor is about 15cm before the crude drugs, and then performing multi-stage countercurrent percolation extraction. The addition amount of 60-65% of fen-flavor liquor for soaking and percolating is 45 (65%) to 49 times (60%) of the weight of the crude residue. Percolation speed: 140 plus or minus 10L/hr, controlling the leaching temperature: 35-40 ℃. The 60-65% of fen-flavor liquor refers to the volume percentage of the concentration of ethanol contained in the fen-flavor liquor.
Step three: blended wine
1. And C, pumping the extracting solution obtained in the step II into a wine mixing tank, fully and uniformly mixing, and sampling to carry out alcohol content inspection on the extracting solution.
2. And (3) adding the faint scent type white spirit and the yellow wine with specified amounts into the wine preparation tank in the step (1). Wherein, the volume of the added fen-flavor liquor is obtained according to the following calculation formula:
Figure BDA0002497915420000061
wherein, V2Adding fresh-scent Chinese liquor to the required volume2Is faint scent white spirit alcohol content C1Is the alcohol content A, V of the extract1Is the volume of the extract.
3. According to 10000L of the blended wine, the volume of the lacking alcohol is supplemented, then the purified water is supplemented to the specified volume, and the mixture is fully stirred uniformly. Volume of the alcohol in shortage is V3The specific calculation formula is as follows:
Figure BDA0002497915420000062
wherein, V3Distilling to obtain grape extractVolume of wine, C3The alcohol content is the alcohol content of the grape distilled liquor.
4. Adding white sugar and caramel color according to 10000L formula.
5. And after the prepared wine is uniformly stirred, filtering by adopting a diatomite filter and a plate and frame filter.
Step four: freezing
And (4) putting all the semi-finished products obtained in the step three into a freezing tank, starting the freezing tank for freezing, stopping freezing when the freezing temperature reaches-6.5 to-7.5 ℃, and keeping the temperature for more than or equal to 24 hours.
Step five: filtration
Filtering the wine liquid frozen to be warm by a diatomite filter and a plate frame filter while the wine liquid is cold, and checking the clarity of the filtered wine at any time during filtering.
Example 2A tonic three-animal penes wine and its extraction method
This example mainly describes a tonic three-whip wine and its extraction method, which is different from example 1 in that the tonic three-whip wine is prepared from the ingredients shown in table 2.
TABLE 2 Tonic Sanbian wine formula (10000L of each ingredient)
Figure BDA0002497915420000071
The addition amount of the fen-flavor liquor and the grape distilled liquor is added according to the following formula:
the volume calculation formula of the fen-flavor liquor is as follows: 10000L multiplied by 34.0% multiplied by 90% divided by the alcohol content of the fen-flavor liquor.
The calculation formula of the total volume of the added grape distilled wine is as follows: 10000L 34.0% × 10% ÷ alcohol content of wine.
In the third step, the volume V of the fen-flavor liquor is added2The following calculation formula is obtained:
Figure BDA0002497915420000072
V2adding fresh-scent Chinese liquor to the required volume2Is faint scent white spirit alcohol content C1Is the alcohol content A, V of the extract1Is the volume of the extract.
In step three, the volume of the alcohol in shortage is V3The specific calculation formula is as follows:
Figure BDA0002497915420000081
V3to the volume of wine to be added, C3The alcohol content is the alcohol content of the grape distilled liquor.
Example 3A tonic three-animal penes wine and its extraction method
This example mainly describes a tonic three-whip wine and its extraction method, which is different from example 1 in that the tonic three-whip wine is prepared from the ingredients shown in table 3.
TABLE 3 Tonic Sanbian wine formula (10000L of each ingredient)
Figure BDA0002497915420000082
In addition, the addition amount or supplement amount of the fen-flavor liquor, the grape distilled liquor and the yellow wine is added according to the following formula:
the volume total amount calculation formula of the fen-flavor liquor is as follows: 10000L multiplied by 36.0% multiplied by 90% divided by the alcohol content of the fen-flavor liquor.
The calculation formula of the total volume of the added grape distilled wine is as follows: 10000L multiplied by 36.0% multiplied by 10% divided by the alcohol content of the wine.
In the third step, the volume V of the fen-flavor liquor is added2The following calculation formula is obtained:
Figure BDA0002497915420000091
V2adding fresh-scent Chinese liquor to the required volume2Is faint scent white spirit alcohol content C1Is the alcohol content A, V of the extract1Is the volume of the extract.
In step three, the volume of the alcohol in shortage is V3The specific calculation formula is as follows:
Figure BDA0002497915420000092
V3to the volume of wine to be added, C3The alcohol content is the alcohol content of the grape distilled liquor.
Example 4 nutritional Tonic Performance test of Tonic triple Strand wine
The tonic three-whip wine obtained in examples 1 to 3 was subjected to performance tests in terms of alcohol content, total sugar, and the like, and data shown in table 4 were obtained:
TABLE 4 nutritional and tonic performance data
Detecting the index Example 1 Example 2 Example 3
Alcohol content (20 ℃ C.),% (V/V) 35 34 36
Total sugar (in terms of glucose), g/L 60 54 66
Total acid (in terms of acetic acid, g/L) ≤6.0 ≤6.0 ≤6.0
Dry extract (g/L) ≥0.5 ≥0.5 ≥0.5
Total esters (in terms of ethyl acetate) (g/L) ≥0.35 ≥0.35 ≥0.35
As can be seen from Table 4, the tonic three-whip wine obtained by the method of examples 1 to 3 of the present invention meets the requirements of the national standard GB/T27588-2011 in alcohol content, total sugar content, total acid, dry extract and total ester.
In addition, the inventor takes distilled liquor and fermented liquor as liquor bases through experiments, adds edible and medicinal animals and plants and food additives, and carries out blending and mixing to obtain the alcoholic liquor with the changed original liquor base style, adjusts the alcoholic strength and the total sugar content of the tonic three-animal penis liquor, and adjusts the taste of the tonic three-animal penis liquor to meet the requirements of food liquor on the best quality. The wine base with unique mixture ratio realizes the wine flavor of the nourishing three-animal penes wine, and the nourishing three-animal penes wine has unique taste. By adopting a new extraction process, useful components in the animal and plant medicinal materials are fully extracted, the content of total solids in an extracting solution is improved, and the content of dry extract in prepared wine is improved. The full extraction of useful components is further ensured by adding the fen-flavor liquor close to the full amount of the fen-flavor liquor in the prepared liquor. And the ingredients crushed in the soaking process can be ensured to be completely soaked by the fen-flavor liquor by adjusting the soaking amount of the liquor. Parameters such as the temperature of percolation are set, and useful components in the ingredients are extracted to the maximum extent through the percolation in the temperature range; the percolation speed (percolation speed of 5-stage counter-current, average about 28 + -2L/hr per tank) is used for percolation, so that the useful components are completely extracted before the solvent is used up. By adjusting the freezing temperature and the freezing time, the clarity of the wine can meet the sensory requirements after being filtered by the diatomite filter and the plate and frame filter, namely the wine is clear and transparent and has no sediment or suspended matters.
Example 5 extraction Performance test of Tonic Sanbian wine extraction method
The tonic three-whip wines of examples 1 to 3 were weighed and extracted by the conventional method (cyclic extraction) and the extraction methods described in examples 1 to 3, respectively, to obtain the experimental results of comparative examples 1-1, 2-1 and 3-1 and the experimental results of examples 1-2, 2-2 and 3-2 of the present invention, as shown in table 5. As can be seen from Table 5, the extraction methods of examples 1 to 3 of the present invention showed an average increase in the total solid content volume of the extract solution of 10.1% and an average increase in the dry extract volume of 10.0% as compared with the cyclic extraction.
TABLE 5 Experimental results verification of extraction method
Figure BDA0002497915420000101
Further, the inventors conducted the same experiment with reference to the method of CN103060158A, and found that the same compounding ratio of CN103060158A, extracted by the method described in CN103060158A, did not reach 47% by volume of the total solid content of comparative examples 1-1, 2-1 and 3-1, nor did the concentration of the dry extract reach 41% by volume of the total solid content of comparative examples 1-1, 2-1 and 3-1.
The tonic three-whip wines obtained in examples 1 to 3 were tested for collagen, hemoglobin, mucin, ginsenoside, ginseng alkene, and β -sitosterol, and it was found that the presence of various nutritional components was detected in all of examples 1 to 3.
Example 6 testing of Tonic Sanbian wine for animal toxicity and immune Performance
1. Observation of acute toxic effects in animals
30 healthy Swiss mice were used, weighing 10. + -.1 g, male and female halves. The tonic three-whip wine obtained in example 1 was concentrated to 1: 10, by gavage of mice. The experiment was carried out once in the morning and once in the evening, each time 0.3ml/10g mouse weight, and then continuously observed for 10 days. During the experiment, the mice have good activity and appetite, the back hair is glossy, the expression and the urine are not abnormal, and none of 30 used mice die, which is also an abnormal phenomenon. Similar experimental results were obtained by performing toxicity experiments using examples 2 to 3, respectively. The dosage of the experiment is more than 70 times of the clinical dosage, which shows that the nourishing three-penis wine has no obvious acute toxicity.
2. Effects on body weight of Normal animals
30 healthy male Swiss mice were used, weighing about 20g, and were randomly divided into two groups according to weight balance. The mice obtained in example 1 were re-filled with the tonic three-animal penes wine and physiological saline 0.2ml/10g once a day for 10 consecutive days, and the body weights were recorded before and after administration. The body weight experiments were performed using examples 2 to 3, respectively. The experimental result shows that the nourishing three-animal penis wine has no influence on the weight of normal animals.
3. Influence on animal sports physical strength
30 healthy Swiss mice with weight of about 10g are divided into groups according to weight balance and randomness, and the physiological saline and the tonic three-penis wine obtained in the example 1 are respectively added with 0.2ml/10g of mice to be re-filled with stomach, and the mixture is taken once a day for 10 days. On the eleventh day of the experiment, the rotating rod is adjusted to rotate at a speed of 10 circles/minute, the animals are placed on the rod one by one, and the retention time of the animals on the rod is recorded, namely the time of physical consumption of the animals during movement and the bearing time of the physical strength of the animals. Physical force experiments were performed using examples 2 to 3, respectively. The result shows that the nourishing three-penis wine has the function of improving the physical strength and the movement tolerance of animals.
4. Influence on body weight, plasma cortisol content and adrenal weight of yang-deficient animals.
100 healthy male Swiss mice weighing about 15 g were injected subcutaneously with 0.5% hydrocortisone 0.1 ml/day for 9 consecutive days. During the period, the weight of the animals is obviously reduced, about 12 g on average, about 40 percent of the animals die, and the surviving animals all have loose hair, aversion to cold, inappetence and cachexia. On the 10 th day of the experiment, the animals were divided into two groups according to the weight random equilibrium, and the animals were re-filled with normal saline and the tonic three-whip wine obtained in examples 1 to 3 in an amount of 0.2ml/10g, once a day for 12 consecutive days, and the weight was recorded every 4 days during the experiment, and the results were recorded. On the 21 st day of the experiment, the eyeballs of the mice are removed, blood is taken from the orbital veins, heparin is used for anticoagulation, after centrifugation, plasma is quantitatively sucked, and the plasma cortisol content is measured by using an EJ-2008r immune counter. Differences between groups were compared using the T-test method. Weighing blood and adrenal gland, taking adrenal gland on both sides, fixing in Bownis solution for 24 hours, then sucking surface liquid with filter paper, removing fat and other tissues, weighing wet weight, converting to adrenal gland mg wet weight/10 mouse weight, and performing statistical treatment by an inspection method. The effects on plasma cortisol and adrenal weight suggest that the tonic triple penes obtained in examples 1 to 3 increase the body weight of experimental mice, and enhance the adrenal endocrine function of mice, and the weight of adrenal glands of mice increases.
The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (10)

1. The tonic three-animal penes wine is characterized by being prepared from the following ingredients: each 10000L of ingredients comprise 0.2-0.7 kg of seal penis, 0.5-1.2 kg of deer penis, 4.5-7 kg of dog penis, 9-12 kg of ginseng, 8-10 kg of cinnamon, 18-20 kg of medlar, 20-22 kg of tuckahoe, 25-35 kg of yam, 2-6 kg of pepper, 3-5 kg of fennel, fen-flavor liquor, distilled grape wine, 15-25L of yellow wine, 500-600 kg of white granulated sugar and 6-10L of caramel color.
2. A tonic trichuris wine according to claim 1, wherein the alcoholic strength of the tonic trichuris wine is 34-36% vol and the total sugar content is 54-66 g/L.
3. A tonic three whip wine as claimed in claim 1, wherein said fen-flavor liquor is 10000L x N% × 90% ÷ M, and said wine distillate is 10000L x N% × 10% ÷ G; wherein M is the alcohol content of the fen-flavor liquor, N is the numerical value of the alcohol content of the tonic three-whip liquor, and G is the alcohol content of the grape distilled liquor.
4. A method for extracting tonic three-animal penes wine is characterized in that the ingredients of claim 1 or 3 are weighed, and then the obtained ingredients are processed by pretreatment, extraction, wine preparation, freezing and filtration;
the pretreatment comprises crushing the obtained ingredients;
the extraction comprises the steps of soaking the crushed ingredients in fen-flavor liquor, performing multi-stage countercurrent percolation extraction and obtaining an extracting solution;
the wine blending comprises adding Chinese liquor, yellow wine and grape distilled liquor into the extracting solution.
5. The extraction method according to claim 4, wherein the weight of the fen-flavor liquor is 45-49 times of the weight of the crushed ingredients.
6. The extraction method according to claim 4, wherein the extracting comprises: the height of the ingredients of the fen-flavor liquor for soaking is not less than 15 cm.
7. The extraction method according to claim 4, wherein the speed of the percolation is 140 ± 10L/hr, and the temperature of the percolation is 35-40 ℃.
8. The extraction method according to claim 4, wherein the freezing comprises: the freezing temperature is-6.5 to-7.5 ℃, and the freezing time is not less than 24 hours.
9. Use of a tonic triple whip wine as claimed in any one of claims 1 to 3 in the medical and cosmetic fields.
10. Use of a tonic three-whip wine prepared by the extraction process according to any one of claims 5 to 8 in the medical and cosmetic fields.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112143609A (en) * 2020-10-30 2020-12-29 烟台中亚医药保健酒有限公司 Tonic and nutritious three-penis wine and its extraction method
CN112195090A (en) * 2020-10-30 2021-01-08 烟台中亚医药保健酒有限公司 Sugar-free three-penis wine and preparation process thereof

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Publication number Priority date Publication date Assignee Title
CN103060158A (en) * 2012-12-31 2013-04-24 威海金颐阳药业有限公司 Three-penis liquor capable of tonifying kidney
CN110917284A (en) * 2019-12-31 2020-03-27 烟台中亚医药保健酒有限公司 Ginseng-antler-three-penis wine capable of strengthening male sexual capacity and preparation method thereof
CN111019797A (en) * 2019-12-31 2020-04-17 烟台中亚医药保健酒有限公司 Preparation process of three-penis wine

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
CN103060158A (en) * 2012-12-31 2013-04-24 威海金颐阳药业有限公司 Three-penis liquor capable of tonifying kidney
CN110917284A (en) * 2019-12-31 2020-03-27 烟台中亚医药保健酒有限公司 Ginseng-antler-three-penis wine capable of strengthening male sexual capacity and preparation method thereof
CN111019797A (en) * 2019-12-31 2020-04-17 烟台中亚医药保健酒有限公司 Preparation process of three-penis wine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112143609A (en) * 2020-10-30 2020-12-29 烟台中亚医药保健酒有限公司 Tonic and nutritious three-penis wine and its extraction method
CN112195090A (en) * 2020-10-30 2021-01-08 烟台中亚医药保健酒有限公司 Sugar-free three-penis wine and preparation process thereof

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