CN111572971B - Device for preserving umbilical cord blood stem cells - Google Patents

Device for preserving umbilical cord blood stem cells Download PDF

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Publication number
CN111572971B
CN111572971B CN202010458521.7A CN202010458521A CN111572971B CN 111572971 B CN111572971 B CN 111572971B CN 202010458521 A CN202010458521 A CN 202010458521A CN 111572971 B CN111572971 B CN 111572971B
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CN
China
Prior art keywords
pressure
plate
box body
stem cell
plates
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Expired - Fee Related
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CN202010458521.7A
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Chinese (zh)
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CN111572971A (en
Inventor
王芳
胡建霞
牛佳鹏
陈爱霞
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Affiliated Hospital of University of Qingdao
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Affiliated Hospital of University of Qingdao
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Priority to CN202010458521.7A priority Critical patent/CN111572971B/en
Publication of CN111572971A publication Critical patent/CN111572971A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/10Devices to locate articles in containers
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0263Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/04Partitions
    • B65D25/06Partitions adapted to be fitted in two or more alternative positions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D43/00Lids or covers for rigid or semi-rigid containers
    • B65D43/02Removable lids or covers
    • B65D43/12Removable lids or covers guided for removal by sliding

Abstract

The invention relates to the technical field of medical equipment, in particular to a device for preserving umbilical cord blood stem cells, which comprises a box body, a pressure isolating plate, a lifting driving mechanism and a fixing mechanism, wherein the pressure isolating plate is arranged on the box body; the number of the pressure isolating plates is more than two, and the pressure isolating plates are sequentially arranged in the box body along the height direction and can be lifted in the box body; a connecting mechanism is arranged between every two adjacent pressure-isolating plates; in the height direction, the upper partition board can be close to or far away from the adjacent lower partition board, and an opening for taking and placing the stem cell collecting bag is formed between the upper partition board and the lower partition board when the upper partition board is lifted and far away to the limit position, and the upper partition board and the lower partition board are linked through a connecting mechanism; the lifting driving mechanism is used for being selectively connected with any pressure isolating plate; the fixing mechanism is used for fixedly connecting any different partition boards. Wherein, medical personnel can only loosen corresponding stem cell collection bag as required, make the collection bag that need not be taken out keep pressfitting state, prevent to take place to damage.

Description

Device for preserving umbilical cord blood stem cells
Technical Field
The invention relates to the technical field of medical equipment, in particular to a device for preserving umbilical cord blood stem cells.
Background
Human cord blood stem cells are usually stored in a cryogenic refrigerator/liquid nitrogen tank at-85 ℃ or-196 ℃ depending on the desired age of storage. For cord blood stem cells with a short period of time after collection (< 6 months), cryopreservation at-85 ℃ is usually performed by using a deep low temperature refrigerator. In a specific operation, the cord blood stem cells are usually collected in a plastic collection bag, then are contained by using a container with a specific structure, such as a device for preserving cord blood stem cells, and are put into a low-temperature refrigerator to reduce the temperature of the human cord blood stem cells.
At present, as shown in fig. 1, a device for storing umbilical cord blood stem cells is disclosed in patent No. CN108207933B, which comprises a box 1, a movable block 2 and a collection bag containing mechanism, wherein the side surface of the box 1 is provided with a box cover capable of being opened and closed, the number of the collection bag containing mechanisms is more than two, and the collection bag containing mechanisms are all arranged in the box 1, the collection bag containing mechanism comprises a support plate 3 and a pressing plate 4 which are arranged in parallel, and a stem cell collection bag 10 is arranged between the support plate 3 and the pressing plate 4. When the box cover is closed, the box cover pushes the pressing plate 4 through the movable block 2, so that the pressing plate 4 presses the stem cell collecting bag 10 to enable the stem cell collecting bag 10 to be flat, and thus, the temperature of each part in the stem cell collecting bag 10 can be uniformly reduced; when the box cover is opened, the pressing plate 4 is far away from the supporting plate 3 under the action of the elastic piece 12 so as to loosen the stem cell collecting bag 10, thus being convenient for medical staff to take and place the stem cell collecting bag 10.
The device for preserving cord blood stem cells for storing stem cells has at least the following defects: in order to save resources, generally, a plurality of stem cell collection bags 10 for different patients are stored in one apparatus for storing cord blood stem cells, and only one stem cell collection bag 10 is placed in each collection bag housing mechanism in order to prevent adhesion. When medical personnel opened the device of preserving cord blood stem cell, the clamp plate 4 on all patients 'stem cell collection bag 10 all kick-backs and opens, and medical personnel takes out the stem cell collection bag 10 back that corresponds the patient, closes the case lid, and other patients' stem cell collection bag 10 is fixed by the clamp plate 4 pressfitting that corresponds again, so lead to the stem cell collection bag 10 that does not take out to take place to damage easily at the relapse loosening and pressfitting in-process, so the urgent need is solved to this kind of condition.
Disclosure of Invention
In view of the above, the present invention provides a device for preserving umbilical cord blood stem cells, and mainly aims to solve the technical problem of how to loosen only the stem cell collecting bag of a specific patient in a box body according to needs, and prevent the stem cell collecting bags of other patients from being damaged in the repeated loosening and pressing processes.
In order to achieve the purpose, the invention mainly provides the following technical scheme:
the embodiment of the invention provides a device for preserving umbilical cord blood stem cells, which comprises a box body, a pressure isolating plate, a lifting driving mechanism, a fixing mechanism and a pressing mechanism, wherein the pressure isolating plate is arranged on the box body; the side surface of the box body is provided with the collecting bag taking and placing opening; the number of the pressure isolating plates is more than two, and the pressure isolating plates are sequentially arranged in the box body along the height direction and can lift in the box body; a connecting mechanism is arranged between every two adjacent partition pressing plates, wherein in the height direction, the partition pressing plate positioned above can be close to or far away from the partition pressing plate positioned below and adjacent to the partition pressing plate, an opening for taking and placing the stem cell collecting bag is formed between the two partition pressing plates when the partition pressing plates are lifted and far away to the limit position, and the two partition pressing plates are linked with the partition pressing plates below and adjacent to the partition pressing plates through the connecting mechanism; the lifting driving mechanism is used for being selectively connected with any pressure isolating plate so as to drive the corresponding pressure isolating plate to lift; the pressure mechanism is used for pressing the stem cell collecting bag through the pressure isolating plate; the fixing mechanism is used for fixedly connecting any different partition pressure plates; the fixing mechanism comprises a connecting plate and a connecting piece, and the connecting plate is provided with a strip-shaped through groove; the connecting piece comprises a screw and a nut, wherein each pressure-isolating plate is provided with a first threaded hole, the screw is used for penetrating through the groove and is in threaded connection with the first threaded hole, and the nut is used for being in threaded connection with the screw and is matched with and fixedly clamped with the nut of the screw.
Optionally, the pressing mechanism includes a driving screw, a second threaded hole is formed in a top plate of the box body, and the driving screw is used for penetrating through the second threaded hole and abutting against the uppermost pressure-isolating plate.
Optionally, a box cover is arranged on the side face of the box body, and the box cover is a rotary opening-closing type cover body.
By means of the technical scheme, the device for preserving the cord blood stem cells has at least the following beneficial effects:
1. medical personnel can only loosen the corresponding stem cell collecting bag according to the needs, so that the stem cell collecting bag which does not need to be taken out is kept in a pressing state, and the stem cell collecting bag which does not need to be taken out can be prevented from being damaged in the repeated loosening and pressing processes;
2. the lifting driving mechanism can be detached relative to the box body, so that when the lifting driving mechanism is not needed to be used, for example, when the device for preserving umbilical cord blood stem cells is placed in a refrigeration house for refrigeration, the lifting driving mechanism can be detached from the box body through the detaching mounting seat, and the lifting driving mechanism can be prevented from being frozen during refrigeration.
The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical solutions of the present invention more clearly understood and to implement them in accordance with the contents of the description, the following detailed description is given with reference to the preferred embodiments of the present invention and the accompanying drawings.
Drawings
FIG. 1 is a schematic diagram of a prior art apparatus for preserving cord blood stem cells;
FIG. 2 is a top view of an apparatus for preserving cord blood stem cells according to an embodiment of the present invention;
FIG. 3 is a schematic view of the apparatus for preserving cord blood stem cells of FIG. 2 with the lid open;
FIG. 4 is a schematic structural view of an upper pressure separator plate relative to an adjacent lower pressure separator plate when raised away from a limit position according to an embodiment of the present invention;
FIG. 5 is a cross-sectional view taken along line A-A of FIG. 2;
FIG. 6 is a partially exploded view of the apparatus for preserving cord blood stem cells of FIG. 3.
Reference numerals: 1. a box body; 2. a pressure-isolating plate; 3. a lifting drive mechanism; 4. a fixing mechanism; 5. a pressure applying mechanism; 6. a connecting mechanism; 7. a slider; 8. a first positioning projection; 9. a second positioning projection; 10. a collecting bag taking and placing opening; 11. a box cover; 12. a top plate; 13. a base plate; 20. an opening; 21. an upper pressure-isolating plate; 22. a lower pressure-isolating plate; 30. a limiting guide groove; 31. a screw; 32. a nut seat; 33. a mounting seat; 34. a drive handle; 41. a connecting plate; 42. a screw; 43. a nut; 51. a drive screw; 61. a connecting rod; 62. a base; 100. a stem cell collection bag; 101. a first stem cell collection bag; 102. a second stem cell collection bag; 103. a third stem cell collection bag; 104. a fourth stem cell collection bag; 121. a second threaded hole; 200. a first threaded hole; 201. a first pressure-isolating plate; 202. a second pressure-isolating plate; 203. a third pressure-isolating plate; 204. a fourth pressure-isolating plate; 321. a first insertion groove; 331. a second insertion groove; 411. passing through a groove; 421. a nut of the screw; 611. hooking; 621. and (7) hanging holes.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that, if directional indications (such as up, down, left, right, front, and back … …) are involved in the embodiment of the present invention, the directional indications are only used to explain the relative positional relationship between the components, the movement situation, and the like in a specific posture (as shown in the drawing), and if the specific posture is changed, the directional indications are changed accordingly.
In addition, if there is a description of "first", "second", etc. in an embodiment of the present invention, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present invention.
As shown in FIGS. 2 and 3, an apparatus for preserving cord blood stem cells according to an embodiment of the present invention comprises a housing 1, a pressure-isolating plate 2, a lifting/lowering driving mechanism 3, a fixing mechanism 4, and a pressing mechanism 5. The side of the box body 1 is provided with a collection bag taking and placing opening 10, and a stem cell collection bag 100 storing stem cells of a patient can be placed into the box body 1 or taken out from the box body 1 through the collection bag taking and placing opening 10. The side of the case 1 may have a cover 11, and preferably, the cover 11 is a rotary opening and closing cover. The number of the pressure-isolating plates 2 is more than two, and the pressure-isolating plates 2 are sequentially arranged in the box body 1 along the height direction. Each pressure-isolating plate 2 can be lifted in the box body 1. Of course, in order to ensure the lifting precision of the pressure-isolating plate 2, it is preferable that the apparatus for preserving cord blood stem cells of the present invention further comprises a limit guide mechanism for limiting and guiding the lifting of each pressure-isolating plate 2. In a specific application example, the limit guide mechanism may include a limit guide groove 30 disposed on a side wall of the box body 1, and a slider 7 is disposed on each partition board 2, wherein each partition board 2 and the slider 7 thereon may be an integrally formed structure. The sliding blocks 7 on the pressure isolating plates 2 are in sliding fit with the limiting guide grooves 30 so as to ascend and descend along the limiting guide grooves 30.
As shown in fig. 3, a connecting mechanism 6 is provided between each adjacent two of the partition boards 2. As shown in fig. 4, in the height direction, the upper partition plate 2 may be closer to or farther from the adjacent lower partition plate 2. In the two adjacent partition plates 2, when the upper partition plate 2 is lifted away to the limit position, an opening 20 for taking and placing the stem cell collection bag 100 is formed between the two partition plates, and the upper partition plate 2 is linked with the adjacent lower partition plate 2 through the connecting mechanism 6. For convenience of description, in two adjacent pressure separators 2, the pressure separator 2 located above is taken as an upper pressure separator 21, and the pressure separator 2 located below is taken as a lower pressure separator 22, and the above "linkage" means that when the upper pressure separator 21 is lifted away from the limit position relative to the lower pressure separator 22 and continues to lift, the upper pressure separator 21 can drive the lower pressure separator 22 to lift together. The "extreme position" mentioned above refers to the maximum position at which the two adjacent partition plates 2 can be relatively apart.
The lifting driving mechanism 3 is selectively connected to any of the pressure-isolating plates 2 to drive the corresponding pressure-isolating plate 2 to lift. The fixing mechanism 4 is used to fixedly connect any of the different partition plates 2. The aforementioned pressing mechanism 5 is used to press the stem cell collection bag 100 through the pressure-isolating plate 2.
As shown in fig. 5, the connection mechanism 6 may be provided between the lowermost partition plate 2 and the bottom plate 13 of the housing 1 among the partition plates 2, so that one stem cell collection bag 100 may be placed between the lowermost partition plate 2 and the bottom plate 13, thereby increasing the accommodation rate of the stem cell collection bag 100 in the housing 1.
The device for preserving cord blood stem cells in fig. 5 is exemplified below, and the device for preserving cord blood stem cells can store four stem cell collection bags 100, and each stem cell collection bag 100 corresponds to a different patient, the four stem cell collection bags 100 are respectively a first stem cell collection bag 101, a second stem cell collection bag 102, a third stem cell collection bag 103 and a fourth stem cell collection bag 104 from bottom to top, wherein a pressure-isolating plate 2 is arranged above each stem cell collection bag 100, and is respectively taken as a first pressure-isolating plate 201, a second pressure-isolating plate 202, a third pressure-isolating plate 203 and a fourth pressure-isolating plate 204 from bottom to top.
In an application scenario of the above apparatus for preserving umbilical cord blood stem cells, as shown in fig. 5, when a medical staff only needs to take out a stem cell collection bag of a certain patient, such as the second stem cell collection bag 102, the fixing mechanism 4 does not need to fix the partition plate 2, at this time, the lifting driving mechanism 3 is connected to the partition plate 2, i.e., the second partition plate 202, which is located immediately above the second stem cell collection bag 102, and the lifting driving mechanism 3 drives the second partition plate 202 to ascend to an extreme position away from the first partition plate 201, and then stops, i.e., the second stem cell collection bag 102 can be released, and the second stem cell collection bag 102 is taken out.
In another application scenario of the above apparatus for preserving cord blood stem cells, as shown in fig. 5, when a medical staff needs to take out stem cell collection bags 100 of more than two patients, but not all stem cell collection bags 100, the fixing mechanism 4 fixes the pressure-isolating plates 2 on both sides of the stem cell collection bag 100 that need not be taken out together, for example, when the medical staff needs to take out the first stem cell collection bag 101, the second stem cell collection bag 102, and the fourth stem cell collection bag 104, the fixing mechanism 4 fixes the pressure-isolating plates 2 on both sides of the third stem cell collection bag 103, i.e. the second pressure-isolating plate 202 and the third pressure-isolating plate 203, then connects the elevation driving mechanism 3 with the fourth pressure-isolating plate 204, and when the fourth pressure-isolating plate 204 is raised, drives both the first pressure-isolating plate 201 and the second pressure-isolating plate 202 to release the corresponding stem cell collection bag 100, that is, the first stem cell collection bag 101, the second stem cell collection bag 102, and the fourth stem cell collection bag 104 can all be removed.
In another application scenario of the above apparatus for preserving cord blood stem cells, as shown in fig. 5, when a medical worker needs to take out all stem cell collection bags 100, the fixing mechanism 4 does not need to fix the partition plate 2 at this time, and only needs to connect the lifting mechanism with the uppermost partition plate 2, i.e. the fourth partition plate 204, and when the lifting mechanism drives the fourth partition plate 204 to ascend, the fourth partition plate 204 drives the other partition plates 2 to release the corresponding stem cell collection bags 100 together, so that all stem cell collection bags 100 can be taken out.
In the above example, the medical staff may only loosen the corresponding stem cell collection bags 100 as needed, so that the stem cell collection bags 100 that do not need to be taken out are kept in a pressed state, and thus, the stem cell collection bags 100 that do not need to be taken out may be prevented from being damaged during repeated loosening and pressing.
In order to realize the function of the connecting mechanism 6, when the upper pressure-isolating plate 2 is lifted to a limit position relative to the adjacent lower pressure-isolating plate 2 and is further lifted, the adjacent lower pressure-isolating plate 2 can be driven by the connecting mechanism 6 to lift together, as shown in fig. 4, the connecting mechanism 6 may include a link 61 and a base 62. The connecting rod 61 may be provided with a hook 611 fixed by welding, for example, and the base 62 is provided with a hanging hole 621. The connecting rods 61 and the bases 62 are disposed on the two adjacent pressure-separating plates 2 in a one-to-one correspondence, that is, in the two adjacent pressure-separating plates 2, the connecting rods 61 are disposed on one of them, and the bases 62 are disposed on the other. The hook 611 is configured to extend into the hanging hole 621 and can move along the length direction of the hanging hole 621, and hook on one side of the length direction of the hanging hole 621 when the upper pressure-isolating plate 2 rises and moves away from the limit position, so that the upper pressure-isolating plate 2 can drive the adjacent lower pressure-isolating plate 2 to rise together when continuing to rise.
Further, as shown in fig. 4, the connecting rod 61 may be a guide rod, and the base 62 may be a guide cylinder. The guide rod and the guide cylinder are in insertion fit. The aforementioned hanging holes 621 penetrate through opposite sides of the base 62. So the guide bar can be opened and shut relatively of two adjacent pressure plates 2 with the cooperation of guide cylinder and lead to improve two adjacent pressure plates 2 that separate the precision that opens and shuts. Thus, it should be noted that: the relative distance between two adjacent partition boards 2 can be interpreted as relative opening, and the relative approach between two adjacent partition boards 2 can be interpreted as relative closing.
In order to realize the function of the lifting mechanism, the lifting mechanism can be selectively connected with any one of the pressure-isolating plates 2 to drive the corresponding pressure-isolating plate 2 to lift, as shown in fig. 6, the lifting mechanism can include a mounting seat 33, a screw 31 and a nut seat 32. The mounting seat 33 is used for mounting on the case 1, such as fixedly or detachably mounting on the case 1. The screw 31 is rotatably provided on the mount 33, and a bearing may be installed therebetween. The nut seat 32 is used for being sleeved on the screw rod 31 and is in threaded connection with the screw rod 31. The nut seat 32 is further provided with a detachable connecting structure, and the lifting driving mechanism 3 can be selectively connected with any one of the pressure-isolating plates 2 through the detachable connecting structure. Wherein, because there is spacing guiding mechanism to each pressure-isolating plate 2 spacing and direction to when the detachable connection structure on the nut seat 32 is connected with pressure-isolating plate 2, the aforesaid spacing guiding mechanism also can be spacing to the lift of nut seat 32, so make the screw 31 drive the nut seat 32 to go up and down when rotating, and then nut seat 32 drives the pressure-isolating plate 2 that links to each other with it and goes up and down together.
As shown in fig. 6, a driving handle 34 may be disposed on the screw rod 31, and the medical staff may drive the screw rod 31 to rotate through the driving handle 34, so that the operation is convenient.
In order to realize the function of selectively connecting the lifting drive mechanism 3 with any one of the pressure-isolating plates 2 through the detachable connecting structure, as shown in fig. 6, the detachable connecting structure may be a first insertion groove 321 provided on the nut holder 32. Each partition board 2 is provided with a first positioning protrusion 8, and each first positioning protrusion 8 is used for being inserted into the first insertion groove 321. The nut seat 32 is of a two-half open-close structure and is detachable relative to the screw 31. Specifically, the nut seat 32 has half grooves on both halves, and the half grooves form the first insertion groove 321 when the half grooves are combined. Half threaded holes are also formed in the two halves of the same nut seat 32, and the two half threaded holes can form a threaded hole sleeved on the screw 31 together. The two halves of the nut seat 32 may be connected by bolts or the like so that the two halves of the nut seat 32 can be opened and closed. When the two halves of the nut seat 32 are opened, the nut seat 32 can be detached relative to the screw 31; when the two halves of the nut seat 32 are closed, the nut seat 32 can be sleeved on the screw 31 and is in insertion fit with the first positioning protrusion 8 on the pressure-isolating plate 2 through the first insertion groove 321 on the nut seat.
In the above example, since the nut holder 32 is of a two-half openable structure, it can be easily connected to the screw 31 and any partition plate 2 after the two halves are opened relatively.
In order to improve the connection stability between the nut seat 32 and the pressure-isolating plate 2, it is preferable that the first positioning protrusion 8 is inserted into the first insertion groove 321 and then connected to the nut seat 32 by a bolt.
As shown in fig. 6, preferably, the mounting seat 33 is detachable with respect to the box body 1, for example, the mounting seat 33 may be provided with a second insertion groove 331, and the box body 1 is provided with a second positioning protrusion 9. The second positioning protrusion 9 is for being inserted into the second insertion groove 331. The second positioning protrusion 9 is matched with the second insertion groove 331 to achieve the function that the mounting seat 33 is detachable relative to the box body 1.
In the above example, since the mount 33 is detachable with respect to the casing 1, when it is not necessary to use the elevation drive mechanism 3, such as when the apparatus for preserving cord blood stem cells of the present invention is put into a refrigerator for refrigeration, the elevation drive mechanism 3 can be detached from the casing 1 by detaching the mount 33, so that the elevation drive mechanism 3 can be prevented from being frozen out at the time of refrigeration.
In order to fulfill the function of the aforementioned fixing mechanism 4, enabling the fixing mechanism 4 to fix any of the different partition plates 2 together, as shown in fig. 5, the fixing mechanism 4 may include a connecting plate 41 and a connecting member. The connecting plate 41 is provided with a strip-shaped through slot 411. The connector comprises a screw 42 and a nut 43. Each pressure-isolating plate 2 is provided with a first threaded hole 200. Wherein, the screw 42 is used to pass through the through slot 411 and is screwed in the first screw hole 200, so that the screw 42 can be kept fixed with the partition board 2. The nut 43 is screwed on the screw 42 and cooperates with the nut of the screw 42 to clamp the connecting plate 41, so that the screw 42 can be fixed to the connecting plate 41. When the screws 42 of different connecting members are connected with different pressure-isolating plates 2, the pressure-isolating plates 2 connected with the screws 42 can be fixed together because each screw 42 is kept fixed relative to the connecting plate 41.
As shown in fig. 5, the aforementioned pressing mechanism 5 may include a drive screw 51. The top plate 12 of the case 1 is provided with a second screw hole 121, and the drive screw 51 is inserted through the second screw hole 121 and abuts against the uppermost partition plate 2. When the driving screw 51 is screwed, a force can be applied to each of the lower pressure-isolating plates 2 through the uppermost pressure-isolating plate 2 to press each of the stem cell collection bags 100; when the driving screw 51 is screwed in the opposite direction, the pressure-isolating plates 2 can be loosened, so that the pressure-isolating plates 2 can be driven by the lifting driving mechanism 3 to lift.
The working principle and preferred embodiments of the present invention are described below.
The invention aims to design a device for preserving umbilical cord blood stem cells, and medical staff can only loosen corresponding stem cell collecting bags 100 according to needs, so that the stem cell collecting bags 100 which do not need to be taken out are kept in a pressed state, and the stem cell collecting bags 100 which do not need to be taken out can be prevented from being damaged in the repeated loosening and pressing processes.
When the stem cell collection bag is used, the driving screw 51 is firstly unscrewed, and then each stem cell collection bag 100 is placed between two adjacent pressure isolation plates 2; then screwing the driving screw 51, wherein the driving screw 51 is pressed against the uppermost insulating plate 2, and the uppermost insulating plate 2 drives the lower insulating plates 2 to press the corresponding stem cell collecting bags 100, so that each stem cell collecting bag 100 is flat; the apparatus for preserving cord blood stem cells of the present invention is then placed in a refrigerator for refrigeration. When the stem cell collecting bag 100 of a certain patient needs to be taken out, the box body 1 is opened, then the nut seat 32 on the lifting driving mechanism 3 is connected with the corresponding pressure isolating plate 2, the fixing mechanism 4 is reasonably arranged, and the lifting driving mechanism 3 drives the corresponding pressure isolating plate 2 to ascend, so that the stem cell collecting bag 100 of the corresponding patient can be taken out. The specific connection between the lifting driving mechanism 3 and the fixing mechanism 4 and the partition board 2 can refer to the description of the corresponding application scenario above, and is not described herein again.
Here, it should be noted that: in the case of no conflict, a person skilled in the art may combine the related technical features in the above examples according to actual situations to achieve corresponding technical effects, and details of various combining situations are not described herein.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may occur to those skilled in the art without departing from the principle of the invention, and are considered to be within the scope of the invention.

Claims (2)

1. A device for preserving cord blood stem cells is characterized by comprising a box body (1), a pressure isolating plate (2), a lifting driving mechanism (3), a fixing mechanism (4) and a pressing mechanism (5); the side surface of the box body (1) is provided with a collecting bag taking and placing opening (10);
the number of the pressure isolating plates (2) is more than two, and the pressure isolating plates (2) are sequentially arranged in the box body (1) along the height direction and can be lifted in the box body (1); a connecting mechanism (6) is arranged between every two adjacent pressure separating plates (2), wherein in the height direction, the pressure separating plate (2) positioned above can be close to or far away from the pressure separating plate (2) positioned below and adjacent to each other, an opening (20) for taking and placing the stem cell collecting bag (100) is formed between the pressure separating plates when the pressure separating plates are lifted and far away to the limit position, and the pressure separating plates are linked with the pressure separating plates (2) below and adjacent to each other through the connecting mechanism (6);
the lifting driving mechanism (3) is selectively connected with any pressure isolating plate (2) to drive the corresponding pressure isolating plate (2) to lift; the pressing mechanism (5) is used for pressing the stem cell collecting bag (100) through the pressure isolating plate (2);
the fixing mechanism (4) is used for fixedly connecting any different partition pressure plates (2); the fixing mechanism (4) comprises a connecting plate (41) and a connecting piece, and a strip-shaped through groove (411) is formed in the connecting plate (41); the connecting piece comprises a screw (42) and a nut (43), each pressure partition plate (2) is provided with a first threaded hole (200), the screw (42) is used for penetrating through the through groove (411) and is in threaded connection with the first threaded hole (200), and the nut (43) is used for being screwed on the screw (42) and is matched with a nut of the screw (42) to clamp the connecting plate (41);
the connecting mechanism (6) comprises a connecting rod (61) and a base (62), a hook (611) is arranged on the connecting rod (61), a hanging hole (621) is arranged on the base (62), and the connecting rod (61) and the base (62) are correspondingly arranged on two adjacent pressure-isolating plates (2) one by one; the hook (611) is used for extending into the hanging hole (621), can move along the length direction of the hanging hole (621), and is hooked on one side of the hanging hole (621) in the length direction when the upper pressure isolation plate (2) rises and is far away from the limit position;
the pressing mechanism (5) comprises a driving screw (51), a second threaded hole (121) is formed in a top plate (12) of the box body (1), and the driving screw (51) is used for penetrating through the second threaded hole (121) and abutting against the uppermost pressure-isolating plate (2).
2. The apparatus for preserving cord blood stem cells of claim 1,
the side of the box body (1) is provided with a box cover (11), and the box cover (11) is a rotary opening-closing type cover body.
CN202010458521.7A 2020-05-27 2020-05-27 Device for preserving umbilical cord blood stem cells Expired - Fee Related CN111572971B (en)

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CN114013817B (en) * 2021-11-15 2023-06-06 青岛市中心血站 Constant temperature blood transfer device for blood collection

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Publication number Priority date Publication date Assignee Title
JPS5647055B2 (en) * 1976-03-09 1981-11-07
CN108177878A (en) * 2018-01-06 2018-06-19 谷昌德 Cryopreservation of Human Cord Blood Stem Cells device
CN108184816A (en) * 2018-01-06 2018-06-22 谷昌德 stem cell low temperature storage device
CN108190215A (en) * 2018-01-06 2018-06-22 谷昌德 Cord blood stem cell freezing storage device

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TWI321119B (en) * 2006-12-15 2010-03-01 Au Optronics Corp Container having product protecting structure

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JPS5647055B2 (en) * 1976-03-09 1981-11-07
CN108177878A (en) * 2018-01-06 2018-06-19 谷昌德 Cryopreservation of Human Cord Blood Stem Cells device
CN108184816A (en) * 2018-01-06 2018-06-22 谷昌德 stem cell low temperature storage device
CN108190215A (en) * 2018-01-06 2018-06-22 谷昌德 Cord blood stem cell freezing storage device

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