CN111569171A - Light energy blood product keeps device - Google Patents
Light energy blood product keeps device Download PDFInfo
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- CN111569171A CN111569171A CN202010562854.4A CN202010562854A CN111569171A CN 111569171 A CN111569171 A CN 111569171A CN 202010562854 A CN202010562854 A CN 202010562854A CN 111569171 A CN111569171 A CN 111569171A
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- blood product
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0286—Handling a large number of blood product units, e.g. storage cabinets, blood bank administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3327—Measuring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3368—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3673—General characteristics of the apparatus related to heating or cooling thermo-electric, e.g. Peltier effect, thermocouples, semi-conductors
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
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- Genetics & Genomics (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
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Abstract
The invention provides a light energy blood product preservation device, which relates to the technical field of medical equipment and comprises: the shell temperature adjusting assembly and the light emitting assembly. The temperature adjusting assembly and the light emitting assembly are arranged inside the shell. The shell is of a structure with a cavity inside, and is used for storing the existing light-transmitting blood bag. The light emitting component is arranged on the inner wall of the shell, and the weak light emitted by the light emitting component irradiates towards the light-permeable blood bag stored in the shell. The components in the blood can be correspondingly activated to a certain degree or obtain certain quantity, property and state change according to the biological stimulation effect of weak light, so that certain maintenance can be actively carried out on the blood products in the shell, the activity of the blood components is improved, the blood components can maintain certain activity in a longer time period, namely the blood has higher quality in the longer time period, and the quantity, the property and the function of the preserved blood components can be changed and improved even according to clinical expectation and requirements.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a light energy blood product preservation device.
Background
Blood is a red opaque viscous liquid flowing in blood vessels and the heart, which is composed mainly of plasma and blood cells. In clinical medicine, especially in operation, it is often necessary to transfuse plasma or other blood products to patients to replenish blood lost or lost blood cells of patients, and blood products for clinical transfusion to patients need to be preserved for a while after collection. However, the components in the blood product will die gradually after leaving the human body, which is difficult to avoid, so that the activity of the blood product is gradually reduced, and the effect of the blood product on the patient after being delivered into the patient is directly influenced. For example, when the activity of erythrocytes is reduced, breakage occurs, the number of erythrocytes is reduced, hemolysis occurs due to long storage, and on the other hand, before the operation, it is necessary not only to ensure the activity of the blood product, but also to maintain the temperature of the blood product at a level acceptable for the patient, otherwise the patient may rapidly become unhealthy or even life-threatening.
In order to slow down the inactivation of blood products, the prior art mainly adopts a low-temperature freezing mode, and a bag body containing the blood products is placed in a low-temperature environment, so that each blood cell component can be maintained at a lower metabolism level, and the aging and death caused by the accumulation of metabolites within the storage period are reduced. However, the low temperature environment merely reduces the amount of dead blood cells, and does not block the tendency of the dead blood cells. In addition, because of the preservation mode of low-temperature freezing, the blood product is difficult to be directly used before an operation, and needs to be heated before the operation after the preservation environment is removed, the existing preservation of the blood product only can delay the metabolism speed of the blood in the blood bag in a passive mode, slow down the inactivation speed of the components of the blood product, difficult to improve the activity of the preserved blood components, and complicated operation is needed from the preservation to the use.
Disclosure of Invention
The present invention is directed to overcoming the above-mentioned shortcomings of the prior art, and providing a light-powered blood product storage device, which can stimulate the activity of blood product components in a blood product storage bag, or obtain certain quantity, property and state changes, effectively prolong the storage time of blood products, simplify the storage steps to use, and even change and improve the quantity, property and function of the stored blood components according to clinical expectations and requirements.
In order to achieve the above purpose, the embodiment of the present invention adopts the following technical solutions:
in one aspect of an embodiment of the present invention, there is provided a light-powered blood product preservation device, including: the temperature control device comprises a shell, a light-emitting component and a temperature-adjusting component, wherein the light-emitting component and the temperature-adjusting component are arranged in the shell; the shell is internally provided with a cavity for accommodating a blood bag; the light-emitting component is arranged on the inner wall of the shell and used for emitting weak light towards the blood bag; the temperature adjusting component comprises a heat insulating layer arranged on the inner wall of the shell and a temperature adjuster, and the temperature adjuster is used for adjusting the temperature of the chamber.
Optionally, the light emitting component is a first lamp strip, and the first lamp strip is spirally wound on the inner wall of the shell;
or the light-emitting component comprises a plurality of second lamp belts, and each second lamp belt is connected end to end and annularly arranged on the inner wall of the shell; the adjacent second lamp belts are arranged in parallel;
or the light-emitting component comprises a plurality of light emitters which are uniformly distributed along the inner wall of the shell.
Optionally, the casing is further provided with a light homogenizing member, and the light homogenizing member is located on the light emitting side of the light emitting assembly and at least covers the light emitting surface of the light emitting assembly.
Optionally, the light uniformizing element includes a light transmitting plate and a nanoparticle layer disposed on the light transmitting plate, and the light transmitting plate at least covers the light emitting surface of the light emitting assembly.
Optionally, a partition plate connected with the inner wall of the shell is arranged in the shell; the partition plate is used for dividing the chamber into a plurality of sub-chambers.
Optionally, the partition plate is a light shielding partition plate, and the light emitting assembly is further arranged on the light shielding partition plate.
Optionally, the temperature adjusting assembly includes a plurality of temperature adjusters, and the plurality of temperature adjusters respectively correspond to the plurality of sub-chambers one to one, and are used for respectively adjusting the temperature of each sub-chamber.
Optionally, the temperature regulator includes a controller, and a temperature sensor and a temperature controller electrically connected to the controller, respectively; the temperature sensor is used for collecting the temperature information in the chamber, and the controller is used for acquiring the temperature information and controlling the temperature controller to adjust the temperature in the chamber according to the temperature information.
Optionally, an openable cabinet door is arranged on one side of the housing, and a sealing strip is arranged at the closed position of the cabinet door and the housing.
The beneficial effects of the invention include:
the invention provides a light energy blood product preservation device, comprising: the temperature control device comprises a shell, a light emitting assembly and a temperature adjusting assembly. The light emitting component and the temperature adjusting component are arranged inside the shell. The shell is of a structure with a chamber inside, and the chamber is used for storing a blood bag for temporarily storing a blood product in the prior art. The light-emitting component can emit weak light in the power-on state, the weak light refers to the irradiation light of low power density or low energy radiation, the wavelength is usually 280-10000nm, especially usually 380-2000nm, and the power output to the irradiation part is 0.01-90mw/cm2The energy density of the irradiation light can be adjusted by adjusting the irradiation time. For example, red light (wavelength is 635 +/-5 nm) and output power is 20mw/cm2Outputting 2 times per day with energy density of 2J/cm2. There is evidence that blood product components can be activated by low light irradiation, such as by irradiation with a 10mw helium neon laser, the viscosity of blood decreases, and the activities of lactate dehydrogenase and potassium, sodium, etc. increase. The light-emitting component is arranged on the inner wall of the shell, so that the bag body of the blood product stored in the shell can be irradiated uniformly and comprehensively in all directions of the inner wall of the shell. Simultaneously, still be provided with the heat preservation on the inner wall of casing, still be provided with temperature regulator on the casing, it can be adjusted the temperature in the chamber as required, for example can be so that the temperature in the chamber is in lower temperature interval in the stage of preserving, before the needs operation, through the mode of adjustment temperature, convenient with the temperature regulation in the chamber in the temperature interval of suitable patient's input, in addition, can also further make the temperature environment of the inside of chamber independently open with external temperature environment through the heat preservation. When the blood in the light-permeable blood bag is irradiated by weak light, the components in the blood product can be preserved according to the biological stimulation of the weak lightTo sustain even a certain degree of increased activity or to achieve certain quantitative, qualitative, state changes. Therefore, the temperature adjusting component can actively control the temperature of the preservation environment to improve the blood product to rapidly enter the pre-operation state to be used, and meanwhile, the blood product in the shell is actively maintained to a certain extent, namely, the blood product has higher quality in a longer time period, the inactivation speed of blood product components is effectively reduced, and even the quantity, the property and the function of the preserved blood components can be changed and improved according to clinical expectation and requirements.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic diagram of a light-powered blood product preservation apparatus according to an embodiment of the present invention;
FIG. 2 is a second schematic structural view of a light-powered blood product preservation apparatus according to an embodiment of the present invention;
FIG. 3 is a third schematic structural view of a light-powered blood product preservation apparatus according to an embodiment of the present invention;
FIG. 4 is a fourth illustration of the structure of a light-powered blood product preserving device according to an embodiment of the present invention;
FIG. 5 is a fifth schematic view of a light-powered blood product preservation apparatus according to an embodiment of the present invention;
fig. 6 is a sixth schematic structural view of a light-energy blood product preserving device according to an embodiment of the present invention.
Icon: 100-a housing; 101-a second light strip; 102-a roller; 103-a first light strip; 104-a light emitter; 1051-diaphragm plate; 1052-vertical baffles; 106-a handle; 107-cabinet door; 108-a viewing window; 200-blood bag.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. It should be noted that, in the case of no conflict, various features in the embodiments of the present invention may be combined with each other, and the combined embodiments are still within the scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are only for convenience of describing the present invention and simplifying the description, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
In the description of the present invention, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly unless otherwise specifically indicated and limited. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In one aspect of an embodiment of the present invention, referring to fig. 1, there is provided a light-powered blood product preserving apparatus including: a housing 100, and a light emitting assembly and a temperature adjusting assembly disposed inside the housing 100; the housing 100 has a chamber therein for accommodating the blood bag 200; the light emitting assembly is disposed on the inner wall of the housing 100, and is used for emitting weak light toward the blood bag 200; the temperature adjusting assembly includes an insulating layer disposed on an inner wall of the case 100 and a temperature adjuster for adjusting the temperature of the chamber.
Illustratively, as shown in fig. 5, a chamber is provided inside the housing 100, and at the same time, a light-permeable existing blood bag 200 is placed in the chamber inside the housing 100, and at the same time, as shown in fig. 1, a light emitting assembly is provided on the inner wall of the housing 100. And current is introduced into the light-emitting component, so that the light-emitting component emits weak light in the working state. In order to enable the blood stored in the blood bag 200 to be irradiated by weak light, the light emitting direction of the light emitting component is corresponding to the position of the blood bag 200, and at least the range of the blood bag 200 can completely cover the irradiation of the weak light. Meanwhile, the temperature adjusting component is further arranged in the chamber, so that the temperature environment in the shell 100 can be adjusted, the blood product in the blood bag 200 can be conveniently and rapidly stored and switched to a state to be used in a mode of adjusting the temperature environment where the blood product is located according to needs, the storage and the use convenience are improved, and meanwhile, the unnecessary damage caused by the vibration to the components contained in the blood product in the blood bag 200 in the existing process of moving the blood bag 200 out of the storage environment and transferring the blood bag 200 before use is avoided, so that the quality of the blood product is reduced. Specifically, the temperature regulating assembly comprises an insulating layer and a temperature regulator. When weak light irradiates blood, the components in the blood product can achieve the purpose of enhancing activity under the action of biological stimulation, and the mode is to actively enhance the activity of the components in the blood product in the blood bag 200, effectively reduce the inactivation speed of the components in the blood product, improve the preservation quality of the blood product in the preservation period, and thus be beneficial to improving the treatment effect in the follow-up clinical treatment. In addition, can also be through setting up temperature regulator in casing 100 inside, thereby utilize its temperature regulation's ability to make the inside cavity of casing 100, it is in the suitable temperature that does benefit to preserve promptly to preserve the environment, specifically can carry out reasonable setting according to the kind of the blood products that preserve, it then can be so that the temperature environment in the cavity is in suitable interval within range all the time to set up the heat preservation on casing 100 inner wall, the frequent start-up of temperature regulator has been avoided, when reducing light energy blood products and preserving the device consumption in this application, temperature regulator's life has still been prolonged. For example, when the blood product is a whole blood and red blood cell preparation, it may be set at 2 to 6 degrees celsius; when the blood product is platelet concentrate or granulocyte concentrate, it can be set at 20 to 24 degrees celsius; when the blood product is fresh frozen plasma or cryoprecipitate, the storage time can be set to be between minus 30 and minus 65 degrees centigrade, and the like. Since rapid infusion of cryogenic blood products into a patient during surgery can cause rapid temperature loss in the patient, and can be serious or even life-threatening, it is desirable to minimize the time required to switch the blood product from a storage state to a ready-to-use state and the switching steps in order to provide more time for the patient to be treated. When the blood product in the preservation state needs to be used, the blood product in the preservation state can be quickly switched to the pre-operation state to be used in a temperature increasing mode through the temperature regulator, and the steps during switching are simplified.
The biological stimulation effect of weak light on components in blood products is mainly shown in the following aspects: the weak light also has a biostimulating effect on red blood cells without mitochondria by acting on molecules that contain chromophores in the cells. The activity of chromophore in blood is increased, and the damage caused by the concentration change of active oxygen, calcium ions and nitric oxide is reduced, so that blood cells are effectively activated, the structure and function of cell membranes are changed, the stability of the membranes is improved, the deformability of red blood cells is enhanced, the intercellular repulsion is increased, and the aggregative property of red blood cells and platelets is reduced, so that the red blood cells and platelets are not easy to aggregate and coagulate. Increase the movement of the red blood cells, increase the aggregation resistance, reduce the viscosity of the blood and improve the microcirculation of the blood. The activity of cells in blood is effectively improved by various modes such as activating the activity of various enzymes, improving the rheology of blood, increasing the expression of related genes and the like. For example, low-energy helium neon laser irradiates red blood cells, white blood cells, platelets, proteins, lipids, inorganic salts, trace elements, gases and metabolites in blood to enable the red blood cells, the white blood cells, the platelets, the proteins, the lipids, the inorganic salts, the trace elements, the gases and the metabolites to obtain energy, so that various metabolic processes of an organism are enhanced. On the other hand, the levels of alpha 1-antitrypsin and alpha 2-globulin can also be decreased, resulting in activation of the fibrinolytic system and a decrease in fibrinogen.
First, the light emitting module may be powered by a storage battery disposed in the cavity inside the housing 100, and in order to improve convenience of use, the storage battery may be a rechargeable storage battery, a charging interface is disposed on an outer wall of the housing 100, and in order to further expand a usable environment of the light-energy blood product storage device, a sealing valve may be disposed at the charging interface, so as to enhance dust-proof, water-proof, and impact-proof performance of the power supply. In addition, a power plug of the light emitting device may be directly disposed on an outer wall of the housing 100, so as to supply power to the light emitting device through an external socket.
Second, the above-mentioned weak light is not measured by physical parameters. In medicine, the strong light and the weak light are distinguished by the strength of biological effects generated after the laser itself acts on biological tissues, and the weak light referred to in the application refers to the light with the weak reaction level which can stimulate organisms to generate a series of physiological and biochemical response reactions when the organisms are directly irradiated by the low-strength light, so that the aim of activating cell activity is fulfilled, and irreversible damage can not be caused to target tissues.
Thirdly, the parameter wavelength of the weak light can be 280-10000nm, and can be light with the wavelength of 632.8, 820, 830 or 904nm and other wave bands; the power is primarily 10-90mw (of course, a few may be less than 10mw or greater than 100 mw); the waveform is mainly continuous wave or pulse wave (1-4000 Hz); the energy density is about 1-4J/cm2In the meantime. The weak light may be He-Ne laser (corresponding to the wavelength of 632.8nm), or GaAlAs laser (corresponding to the wavelength of 632.8nm)820, 830nm long), GaAs laser (corresponding to the above wavelength 904nm), and so on. It should be noted that in selecting the wavelength, a reasonable choice should be made to avoid the selected wavelength producing an activation effect that is less than desired.
Fourthly, the light emitting component corresponding to the weak light can be a semiconductor emitter, a laser emitter, various weak light sources with light emitting performance and meeting the requirements, such as optical fibers and the like. The semiconductor emitter may be an LED emitter and the laser emitter may be a He-Ne laser.
Fifth, the housing 100 may be made of a material having a certain strength, i.e., a hard material, so that the blood bag 200 stored in the housing 100 can be well protected. The shape of the housing 100 may be a rectangular parallelepiped, a cylinder, or other forms.
Optionally, the light emitting component is a first light strip 103, and the first light strip 103 is spirally wound on the inner wall of the casing 100.
As shown in fig. 2, the light emitting component is a first light strip 103, and the first light strip 103 is disposed along an inner wall of the casing 100, wherein, in order to provide more comprehensive weak light coverage for the blood bags 200 at different positions in the casing 100 through the first light strip 103, the first light strip 103 may be spirally raised along the inner wall from the bottom end of the casing 100, and finally the first light strip 103 reaches the top end of the casing 100. The number of the first light strips 103 may be multiple, and the first light strips may be spirally arranged in a mutually parallel and non-intersecting manner, or spirally arranged in an intersecting manner. In addition, the spiral direction of the first light strip 103 may be a vertical direction around the housing 100, or may be a horizontal direction around the housing 100. It should be noted that the first light strip 103 and the second light strip 101 in the subsequent embodiments may be a flexible light strip or a rigid light strip, and this application does not specifically limit the present invention. After casing 100 was provided with cabinet door 107, first lamp area 103 and second lamp area 101 all can be in the suitable breaking of the department that opens and shuts of cabinet door 107 to do not influence opening and shutting of cabinet door 107 and be suitable.
Optionally, the light emitting assembly includes a plurality of second light strips 101, and each second light strip 101 is connected end to end and annularly disposed on an inner wall of the housing 100; the adjacent second lamp strips 101 are arranged in parallel to each other.
For example, as shown in fig. 1, the second light strips 101 may be provided in a plurality of strips, wherein one of the second light strips 101 is surrounded on the inner wall of the casing 100 in an end-to-end manner along the horizontal direction, and the remaining second light strips 101 may be arranged in parallel with the same and at equal intervals along the height direction of the casing 100. In order to further improve the uniformity of the illumination of the light-permeable blood bag 200 inside the casing 100, referring to fig. 3, a plurality of parallel light strips may be further disposed on the top and bottom of the casing 100, and the distance between each light strip is equal to the above-mentioned equal distance, i.e. weak light is emitted from each side of the casing 100 to the blood bag 200 inside the casing 100, so that the illumination range of the weak light can cover all positions of the internal cavity of the casing 100. The adverse situation that weak light is difficult to effectively cover the light-powered blood product storage device after the blood bag 200 positioned in the light-powered blood product storage device is displaced after the light-powered blood product storage device is shaken is avoided. Furthermore, it is also possible to make a plurality of second light strips 101 cross each other, and finally form a grid-shaped arrangement on the inner wall of the housing 100.
Optionally, the light emitting assembly includes a plurality of light emitters 104, and the plurality of light emitters 104 are uniformly distributed along an inner wall of the housing 100.
For example, the present embodiment schematically shows a light emitting assembly arrangement in which a plurality of light emitters 104 are disposed on the inner wall of the housing 100. Referring to fig. 4, the light emitter 104 is a point light source generator of a point light source, and the point light source generators are uniformly arranged on the inner wall of the casing 100, and the uniform arrangement means that the distances between adjacent point light source generators are equal, wherein the distances can be reasonably set according to actual requirements and parameters such as the power of weak light, so as to achieve the optimal activation effect. The point light source generator can be an LED lamp or the like. The light-energy blood product storage device has the advantages of small volume, high integration level and space saving, and is more beneficial to the light-energy blood product storage device, and the light-energy blood product storage device can be smaller and lighter. It should be noted that, when the point light source generator is disposed, when it is disposed only on one side surface of the casing 100, it should be disposed on the bottom surface of the casing 100, so that weak light can be irradiated from bottom to top in use, thereby facilitating uniform sensitization of blood.
Optionally, the housing 100 is further provided with a light homogenizing member, and the light homogenizing member is located on the light emitting side of the light emitting assembly and at least covers the light emitting surface of the light emitting assembly.
For example, in order to further improve the uniformity of the weak light emitted by the light emitting module, a light homogenizing member should be disposed on the light emitting side of the light emitting module, wherein the light homogenizing member may be connected to the inner wall of the housing 100 (either fixedly connected or detachably connected), or may be directly connected to the light emitting module (i.e., covered on the light emitting module). When the light emitting component emits weak light, the weak light can penetrate through the light homogenizing piece to finish final emission, namely, the incident uneven light is converted into more even emergent light by utilizing the light scattering effect of the light homogenizing piece, for example, a point light source or a line light source is converted into a surface light source. Thereby further improving the light receiving uniformity of the blood bag 200 and ensuring that the biological stimulation of the blood in different directions is more uniform and stable. It should be noted that the light uniformizing element can be a light uniformizing plate (i.e. nanoparticles are uniformly dispersed in the light uniformizing plate), or a homogeneous hexagonal light guiding rod (which converts a non-uniform light source into a uniform light source by using the principle of total internal reflection), and the like.
Optionally, the light uniformizing element includes a light transmitting plate and a nanoparticle layer disposed on the light transmitting plate, and the light transmitting plate at least covers the light emitting surface of the light emitting assembly.
For example, when the light homogenizing member is a structure of a light transmitting plate and a nanoparticle layer (a nano light transmitting plate), it may utilize the light scattering effect of nanoparticles uniformly distributed on the light transmitting plate, that is, a process of changing the spatial distribution, polarization state or frequency of the light intensity of the light due to the interaction with molecules (atoms) in a substance when the light propagates. That is, the light is spread in all directions, thereby converting a point light source or a line light source into a surface light source. Wherein, the diameter of the nano particles can be 5-50 microns, and the nano particles can be made of superfine barium sulfate, titanium dioxide and other similar materials. Moreover, the light transmittance is high, the uniformity is better, and the uniformity of the light rays irradiated on different parts of the blood bag 200 is further improved.
The example, when being provided with the heat preservation on the casing body, can also make the casing body be shading casing body, can be provided with the light-absorbing layer of absorption light on the casing body promptly, also can be provided with the reflector layer of reflection light to guarantee inside and outside light and do not take place the interference. Therefore, the temperature of the inner cavity of the light energy blood product preservation device is always maintained at the proper preservation temperature of the blood through the heat preservation layer, so that the preservation time of the blood is further prolonged and the preservation quality of the blood is improved on the basis of actively improving the activity of the blood. The specific arrangement form of the heat-insulating layer can be divided into the following types:
first, the housing body may be made of a hard material having a protective ability, and the heat insulation layer may be a polyurethane foam layer or a glass wool layer having a heat insulation effect, or the like.
Secondly, the casing body can be including first casing 100 and second casing 100, is formed with the intermediate layer between first casing 100 and second casing 100, and the heat preservation sets up in the intermediate layer, and the heat preservation can be aforementioned multiple material layer that has the heat preservation effect, also can be the vacuum layer, is about to take out the gas between first casing 100 and the second casing 100 for form the heat preservation of vacuum form between the two.
Optionally, a partition plate connected to the inner wall of the casing 100 is disposed inside the casing 100; the partition plate is used for dividing the chamber into a plurality of sub-chambers.
For example, as shown in fig. 5, a partition plate is further disposed inside the casing 100 and is connected to an inner wall of the casing 100, and the inner wall may be formed with a groove matching with the thickness of the partition plate, so that the degree of freedom of the partition plate is reduced by the structure of the groove, and the partition plate can be removed only by being drawn out when necessary. In addition, the separation plate can also be connected with the inner wall in a sliding block sliding rail mode, so that the blood bag 200 can be conveniently taken out and put in. Utilize the division board to divide the inside cavity of casing 100 into a plurality of subchambers, simultaneously, the division board still can provide the mode of placing of multistage for blood bag 200 to improve the degree of consistency that blood bag 200 placed in the cavity, make each blood bag 200 homoenergetic reasonable receive the cover of low light. By utilizing the characteristics of the sub-chamber, a plurality of blood bags 200 can be classified and stored. The partition plate may be made of a transparent material, and the above-described functional effects can be achieved without affecting the light irradiation on the inner wall of the casing 100 by utilizing the light transmittance of the partition plate. It should be noted that in other embodiments, the partition plate may be fixedly connected to the inner wall of the casing 100.
In another embodiment, each of the sub-chambers may be further independent from each other, and each of the sub-chambers may further be provided with an independent insulating layer or a heat insulating layer, wherein each of the sub-chambers may further be correspondingly provided with a temperature regulator, so as to further improve the convenience of the light energy blood product preservation device in actual use. For example, when only a small amount of blood product is needed, the temperature of only one or some of the sub-chambers may be adjusted to quickly return to the pre-operative ready-to-use condition. At this point, the ambient temperature in the other subchambers is still in a preserved state.
Optionally, the partition plate includes a horizontal partition plate 1051 and a vertical partition plate 1052; the transverse partition 1051 and the vertical partition 1052 are perpendicular to each other and equally divide the chamber.
For example, when the partition prevention plate includes the horizontal partition plate 1051 and the vertical partition plate 1052, the horizontal partition plate 1051 is stacked and spaced in the height direction of the case 100, and the vertical partition plate 1052 is spaced in the width direction of the case 100 so as to be perpendicular to the horizontal partition plate 1051. The vertical partition 1052 and the transverse partition 1051 divide the chamber into a plurality of sub-chambers, each of which can hold a different blood bag 200. For example, in fig. 5, a transverse partition 1051 and a vertical partition 1052 are provided to divide the chamber in the rectangular parallelepiped housing 100 into four rectangular parallelepiped sub-chambers. The transversal partition 1051 and the vertical partition 1052 may be made of transparent material, such as polymethyl methacrylate (PMMA), commonly known as plexiglass, or Polycarbonate (PC).
Optionally, the partition plate is a light shielding partition plate, and the light emitting assembly is further arranged on the light shielding partition plate.
For example, in order to further improve the light receiving uniformity (including intensity, light receiving area, etc.) of the blood bag 200 in each sub-chamber, and at the same time, also further improve the activation effect in the blood bag 200 in each sub-chamber, the partition plate may be a light shielding partition plate (for example, as shown in fig. 5, a transverse partition plate 1051 and a vertical partition plate 1052 are arranged inside the housing 100, and both are made of light shielding materials), and at the same time, the light emitting component may be arranged on the light shielding partition plate. In this embodiment, the specific form of the light emitting device is not limited, for example, when the light emitting device is a light strip, a continuous or discontinuous light strip may be uniformly disposed on the light shielding partition and the inner wall of the housing 100; in addition, when the light emitting component is in the form of a lamp bead or a lamp particle, the light emitting component can be uniformly arranged on the light shielding partition plate and the inner wall of the shell 100. In addition, the shading partition plate can also comprise a main partition plate which is responsible for basic strength support and a heat preservation or heat insulation material which is arranged on the surface of the main partition plate, so that each sub-chamber is independent from each other (mainly from the aspects of illumination, temperature and the like). Thereby facilitating targeted preservation of each sub-chamber for different types of blood product blood bags 200 for better preservation.
For example, as shown in fig. 5, the inside of the casing 100 is divided into 4 sub-chambers by using the horizontal partition plate 1051 and the vertical partition plate 1052 (the sub-chambers may share one cabinet door 107, or the cabinet doors 107 may be separately provided, for convenience of description, the present embodiment will be described by taking the sharing of one cabinet door 107 as an example), and each sub-chamber is controlled in a partitioned manner, that is, the temperature, the illumination, and the like of each sub-chamber are independently adjusted. The 4 sub-chambers are a platelet storage chamber, an erythrocyte storage chamber, a whole blood storage chamber and a frozen plasma storage chamber respectively. And the weak light generator with correspondingly matched wavelength and output power is arranged according to the type of the blood product stored in each storage room, so that the activation effect is effectively improved. Meanwhile, each sub-chamber can be respectively set to different temperatures according to the type of the preserved blood product so as to achieve longer preservation time.
In another embodiment, each sub-chamber can be set to a mode selection, and multiple modes can be set by the controller, a mode selection knob (which can be operated by a touch screen in other embodiments), a temperature regulator, and different types of weak light generators. For example, each sub-chamber is provided with two modes, namely a (platelet) mode and a (red blood cell) mode (in other embodiments, multiple modes, such as 3, 4, 5, etc., may be provided, corresponding to multiple different blood products), and a corresponding mode is selected according to whether the actually placed blood product is a platelet or a red blood cell (the corresponding mode may be a program set in the controller in advance, and when the mode selection knob is rotated to a predetermined position, the corresponding sub-chamber enters the corresponding mode), so as to achieve the purpose of targeted preservation.
The light-shielding partition plate is made of a light-impermeable material, such as a metal or a crystalline material. In other embodiments, the partition plate may also be made of a light-transmitting material. It should be further noted that, in this embodiment, the irradiation time of the light emitting assembly may also be set reasonably according to actual requirements, for example, the irradiation may be performed continuously; or a plurality of modes such as irradiating for a fixed time after irradiating for a fixed time, and irradiating for a fixed time after intermittent time.
Optionally, the temperature adjusting assembly includes a plurality of temperature adjusters, and the plurality of temperature adjusters respectively correspond to the plurality of sub-chambers one to one, and are used for respectively adjusting the temperature of each sub-chamber.
In an example, the temperature adjusting assembly comprises a plurality of temperature adjusters, and each sub-chamber is arranged corresponding to different temperature adjusters, so that independent temperature adjustment of each sub-chamber is realized. In one aspect, as illustrated in the above examples, different storage periods may be adjusted to different storage temperatures for different types of blood products. On the other hand, when a plurality of sub-chambers are included in one light energy blood product preservation device, when only the blood product in one sub-chamber needs to be used, the temperature can be selectively increased to the suitable temperature for the operation through the operation end (which can be a knob, a touch operation screen and the like), and meanwhile, the preservation of the blood product in other sub-chambers is not influenced, so that the usability and the flexibility of the light energy blood product preservation device can be improved.
Optionally, the temperature regulator includes a controller, and a temperature sensor and a temperature controller electrically connected to the controller, respectively; the temperature sensor is used for collecting the temperature information in the chamber, and the controller is used for acquiring the temperature information and controlling the temperature controller to adjust the temperature in the chamber according to the temperature information.
For example, to further improve the preservation performance of the light-powered blood product preservation device, the temperature regulator may include a controller, and a temperature sensor and a temperature controller. The temperature sensor and the temperature controller respectively use the controller as a central control core and are electrically connected with the controller, the temperature sensor can be used as a sensing end to collect temperature information of a chamber (which can be a sub-chamber when being applied to the last embodiment) inside the shell 100, and the collection mode can be real-time collection or collection at certain intervals. It may be a contact temperature sensor or a non-contact temperature sensor. The temperature controller may be a refrigerator having only a refrigerating function, or may be a device having both a refrigerating function and a heating function (which may achieve the purpose of preparing to make the blood bag 200 quickly enter an appropriate temperature before an operation), so as to cooperate with the heat insulating layer in the foregoing embodiment to achieve a better preservation effect. For example, the casing 100 includes an interlayer, a compressor, a condenser, a capillary tube, an evaporator and other components are disposed at the bottom of the interlayer, the temperature in the chamber is controlled by transferring heat in the chamber to the outside, and meanwhile, a program may be preset in the controller, so that the controller controls the operation of the compressor, the condenser and other components after the difference between the temperature in the chamber and a preset target temperature reaches a certain value, and when the temperature difference value meets a predetermined range, the controller controls the operation of the refrigeration component to keep the temperature in the chamber at a predetermined value or within a predetermined range, thereby effectively saving energy and reducing the use cost of the refrigeration component. The temperature controller can also be set as a semiconductor refrigerator, and the temperature in the cavity is at a reasonable value by utilizing the heat transfer mode of the semiconductor in the electrified state. Similarly, the semiconductor refrigerator can still be precisely controlled by the controller according to the preset program. The temperature controller can also be a water chiller, and the temperature in the chamber is correspondingly increased or decreased by heating or cooling the circulating water, so that the blood bag 200 is at an environment temperature suitable for storage, and meanwhile, the requirement that the blood bag 200 can quickly enter the available temperature before being used in the embodiment is met.
Optionally, an openable cabinet door 107 is arranged on one side of the housing 100, and a sealing strip is arranged at a closed position of the cabinet door 107 and the housing 100; a handle 106 is also provided on the housing 100, and a roller 102 is provided on the bottom of the housing 100.
For example, as shown in fig. 5, in order to improve the convenience of the blood bag 200 during the insertion and removal, a cabinet door 107 may be provided at one side of the housing 100, one side of the cabinet door 107 is hinged to the housing 100, and in order to improve the sealing and safety of the preservation, a mutually-matched fixture or lock may be provided at the other side of the cabinet door 107 and the housing 100. Sealing strips can be arranged on the cabinet door 107 or the housing 100 in a matching way, and the sealing strips are arranged at the closed connecting positions when the cabinet door 107 and the housing 100 are closed. The sealing strip can be made of rubber or silica gel. In order to improve the convenience of the optical blood product preservation device during movement, a handle 106 may be further disposed on the housing 100, and a roller 102 may be disposed at the bottom of the housing 100, wherein the roller 102 may be a universal wheel or the like. As shown in fig. 6, in order to further improve the convenience of the light energy blood product preservation device in the present application, an observation window 108 may be further disposed on the cabinet door 107, so as to avoid light inside the chamber from leaking outwards through the observation window 108, and also avoid interference of external light to light inside the chamber, and further enable the observation window 108 to include a transparent window and a light shielding device, where the light shielding device may be in a hinged form, and when observation is not needed, it may completely shield the transparent window, and when observation is needed, it may be opened in a hinged rotating form to perform observation. Furthermore, the arrangement can be similar to that of a sliding door. In one embodiment, the light-powered blood product storage device may be a small, portable box with a volume of 6L, 10L, 15L, etc., and the upper cover may be a door 107 that can be opened and closed, and the door 107 may be in the form of a snap-fit connection with the housing 100. In another embodiment, the light-powered blood product storage device may be a large storage cabinet having a volume of 1000L, 1500L, 2000L, etc.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (9)
1. A light-powered blood product preservation device, comprising: the temperature control device comprises a shell, a light emitting component and a temperature adjusting component, wherein the light emitting component and the temperature adjusting component are arranged in the shell; the shell is internally provided with a chamber for accommodating a blood bag; the light-emitting component is arranged on the inner wall of the shell and used for emitting weak light towards the blood bag; the temperature adjusting component comprises a heat insulating layer and a temperature adjuster, wherein the heat insulating layer is arranged on the inner wall of the shell, and the temperature adjuster is used for adjusting the temperature of the chamber.
2. The light-powered blood product storage device of claim 1, wherein said light emitting element is a first strip of light helically wound around an interior wall of said housing;
or the light-emitting component comprises a plurality of second lamp strips, and each second lamp strip is annularly arranged on the inner wall of the shell in an end-to-end manner; the adjacent second lamp belts are arranged in parallel;
or the light-emitting component comprises a plurality of light emitters which are uniformly distributed along the inner wall of the shell.
3. The light energy blood product preserving device according to claim 1 or 2, wherein a light homogenizing member is further disposed in the housing, and the light homogenizing member is located on the light emitting side of the light emitting module and at least covers the light emitting surface of the light emitting module.
4. The light-powered blood product preserving apparatus according to claim 3, wherein the light homogenizing member comprises a light-transmitting plate and a nanoparticle layer disposed on the light-transmitting plate, and the light-transmitting plate at least covers the light-emitting surface of the light-emitting assembly.
5. The light energy blood product preservation device of claim 1, wherein a divider is disposed within said housing and connected to an interior wall of said housing; the partition plate is used for dividing the chamber into a plurality of sub-chambers.
6. The light energy blood product preservation device according to claim 5, wherein said divider is a light blocking divider, and said light emitting assembly is further disposed on said light blocking divider.
7. The light energy blood product preservation device according to claim 5, wherein said temperature regulating assembly comprises a plurality of temperature regulators, each of said plurality of temperature regulators corresponding one-to-one to each of said plurality of sub-chambers for regulating the temperature of each of said sub-chambers.
8. The light energy blood product preservation device according to claim 1, wherein said temperature regulator comprises a controller and a temperature sensor and a temperature controller electrically connected to said controller, respectively; the temperature sensor is used for collecting temperature information in the chamber, and the controller is used for acquiring the temperature information and controlling the temperature controller to adjust the temperature in the chamber according to the temperature information.
9. The light-powered blood product preservation device according to claim 1, wherein an openable and closable cabinet door is provided on one side of said housing, and a sealing strip is provided where said cabinet door closes said housing.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112214049A (en) * | 2020-10-10 | 2021-01-12 | 联胜医疗科技(深圳)有限公司 | Temperature control method and system for mobile blood bank |
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| CN201308726Y (en) * | 2008-12-02 | 2009-09-16 | 南通同润生物科技有限公司 | Brain strengthening machine capable of activating brain by near-infrared light |
| CN203227071U (en) * | 2012-12-15 | 2013-10-09 | 钱捷 | Ultraviolet irradiation blood treatment device |
| CN204072915U (en) * | 2014-10-11 | 2015-01-07 | 张�雄 | A kind of Multifunctional full spectrum tachometer system |
| CN204822605U (en) * | 2015-05-13 | 2015-12-02 | 中国人民解放军第三军医大学第二附属医院 | Blood transport case |
| CN106923792A (en) * | 2017-03-21 | 2017-07-07 | 重庆理工大学 | Reflective super portable human body superficial portion vein blood vessel imager |
| CN107456615A (en) * | 2017-09-18 | 2017-12-12 | 佛山迅拓奥科技有限公司 | A kind of blood insulation preserves equipment |
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| CN112214049A (en) * | 2020-10-10 | 2021-01-12 | 联胜医疗科技(深圳)有限公司 | Temperature control method and system for mobile blood bank |
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