CN111529046B - 一种冷冻范围可控的精准治疗冷冻球囊导管装置 - Google Patents
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Abstract
本发明公开了一种冷冻范围可控的精准治疗冷冻球囊导管装置，涉及医疗器械领域，包括鞘管、冷冻球囊和回拉球囊，所述鞘管是弹性材料，所述冷冻球囊和所述回拉球囊均设置在所述鞘管的同一端，所述冷冻球囊与所述鞘管相接触，所述回拉球囊上设置有导杆，所述冷冻球囊上设置有导杆套，所述导杆可在所述导杆套内往复移动，所述导杆和所述导杆套均穿过所述鞘管内部。该发明可控制冷冻消融肺静脉内壁的范围，增加冷冻消融的精准度，避免球囊推动导致冷冻部位与毗邻的膈神经和食道距离过近所带来的副作用及并发症。
Description
技术领域
本发明涉及医疗器械领域，尤其涉及一种冷冻范围可控的精准治疗冷冻球囊导管装置。
背景技术
采用冷冻球囊技术对肺静脉进行隔离来治疗房颤疾病的过程中，需要在肺静脉口处通过冷冻消融形成不可逆的消融灶，进而使得肺静脉中的异常电信号无法传导至左心房。为了使得肺静脉与左心房之间完全隔离，就需要在肺静脉中所形成的消融灶是绕该肺静脉内壁一周且连续的透壁消融灶。但是，目前在对肺静脉进行冷冻消融的过程中，由于无法准确获悉球囊与肺静脉内壁之间的贴合状态，医生只能凭借经验判断球囊与肺静脉内壁贴合的状态，极易出现贴合状态不佳的情况；一旦球囊与肺静脉内壁之间贴合不佳，左心房中流动的血液就会在球囊与肺静脉内壁之间形成冲刺，会大大降低肺静脉内壁冷却的速度，进而使得所形成的消融灶会出现诸如断续、透壁性较差等无法满足治疗需求的缺陷。
本发明要解决的技术问题时如何避免球囊推动导致冷冻部位与毗邻的膈神经和食道距离过近以降低适当损伤和膈神经损伤等并发症的概率。
因此，本领域的技术人员致力于开发一种冷冻范围可控的精准治疗冷冻球囊导管装置，可控制冷冻消融肺静脉内壁的范围，增加冷冻消融的精准度，避免球囊推动导致冷冻部位与毗邻的膈神经和食道距离过近所带来的副作用及并发症。
发明内容
有鉴于现有技术的上述缺陷，本发明所要解决的技术问题是如何避免球囊推动导致冷冻部位与毗邻的膈神经和食道距离过近以降低适当损伤和膈神经损伤等并发症的概率。
为实现上述目的，本发明提供了一种冷冻范围可控的精准治疗冷冻球囊导管装置，包括鞘管、冷冻球囊和回拉球囊，所述鞘管是弹性材料，所述冷冻球囊和所述回拉球囊均设置在所述鞘管的同一端，所述冷冻球囊与所述鞘管相接触，所述回拉球囊上设置有导杆，所述冷冻球囊上设置有导杆套，所述导杆可在所述导杆套内往复移动，所述导杆和所述导杆套均穿过所述鞘管内部。
进一步地，所述回拉球囊是受压后可膨胀的弹性材料。
进一步地，所述导杆设置在所述回拉球囊的轴心线上。
进一步地，所述导杆套设置在所述冷冻球囊的轴心线上。
进一步地，所述鞘管是喇叭状结构，与所述冷冻球囊相接触的一端的直径较大。
进一步地，所述鞘管是网筒装结构。
进一步地，所述鞘管上设置有多个网格。
本发明还提供了一种在肺静脉口处形成不可逆消融灶的方法，包括如下步骤：
1)使所述冷冻球囊和所述回拉球囊与血管壁相接触，所述鞘管的一端和所述冷冻球囊相接触；
2)加压使所述回拉球囊膨胀并对所述血管壁产生径向压力；
3)拉动所述导杆使所述回拉球囊向所述冷冻球囊移动；
4)推动所述鞘管向所述冷冻球囊移动并产生挤压；
5)所述冷冻球囊进行冷冻消融形成消融灶。
进一步地，所述步骤1中的与所述鞘管是喇叭状结构，且和所述冷冻球囊相接处的鞘管的一端直径较大。
进一步地，所述步骤1中的所述冷冻球囊和所述回拉球囊均是生物材料。
该发明可控制冷冻消融肺静脉内壁的范围，增加冷冻消融的精准度，避免球囊推动导致冷冻部位与毗邻的膈神经和食道距离过近所带来的副作用及并发症。
以下将结合附图对本发明的构思、具体结构及产生的技术效果作进一步说明，以充分地了解本发明的目的、特征和效果。
附图说明
图1是本发明的一个较佳实施例的冷冻范围可控的精准治疗冷冻球囊导管装置示意图；
图2是传统冷冻球囊示意图；
图3是本发明的鞘管示意图。
具体实施方式
以下参考说明书附图介绍本发明的多个优选实施例，使其技术内容更加清楚和便于理解。本发明可以通过许多不同形式的实施例来得以体现，本发明的保护范围并非仅限于文中提到的实施例。
在附图中，结构相同的部件以相同数字标号表示，各处结构或功能相似的组件以相似数字标号表示。附图所示的每一组件的尺寸和厚度是任意示出的，本发明并没有限定每个组件的尺寸和厚度。为了使图示更清晰，附图中有些地方适当夸大了部件的厚度。
如图2所示，为避免冷冻球囊1与肺静脉内壁2之间贴合不佳，常通过采用过量贴合的方式，即推动冷冻球囊1使肺静脉内壁2向内部发生形变来提升冷冻球囊1与肺静脉内壁2之间的贴合度，但由于冷冻球囊2推动导致冷冻部位与毗邻的膈神经和食道距离过近，在冷冻消融手中会引起诸如食道损伤、膈神经损伤等手术并发症的概率。
如图1和图3所示，本发明除包括传统冷冻球囊部件外，还包括鞘管4及回拉球囊5。鞘管4为封闭式编织网筒结构，由多个网格6组成。当鞘管4受到挤压，网筒结构将发生形变，即轴向长度缩短，径向长度增加，最大长度为两倍网格6的边长。回拉球囊5从冷冻球囊1内部穿过，可通过外界加压使其膨胀，并可通过外界对其位置进行回拉。回拉球囊5膨胀后与血管壁之间紧密贴合，封堵住血流并对血管产生径向向外的压迫，通过增加接触面积和接触力来达到回拉所需的摩擦力，通过对回拉球囊5的回撤实现对血管的回拉，当冷冻球囊1向鞘管4的方向移动时，可通过摩擦力使血管壁发生一定程度的形变与位移。同时推动鞘管4，使其末端抵住肺静脉内壁2，形成开口喇叭状结构。肺静脉内壁2将在回拉球囊5与鞘管4的共同作用下发生形变，冷冻消融肺静脉内壁接触区域3形成丘状结构，填充入鞘管4的喇叭状结构内。此时冷冻球囊1与血管接触面积降低，同时实现冷冻消融部位远离膈神经、食道等部位，再通过冷冻球囊1对其进行精确冷冻消融。
本发明可控制冷冻消融肺静脉内壁范围，增加冷冻消融的精准度，避免球囊推动导致冷冻部位与毗邻的膈神经和食道距离过近所带来的副作用及并发症。
以上详细描述了本发明的较佳具体实施例。应当理解，本领域的普通技术无需创造性劳动就可以根据本发明的构思作出诸多修改和变化。因此，凡本技术领域中技术人员依本发明的构思在现有技术的基础上通过逻辑分析、推理或者有限的实验可以得到的技术方案，皆应在由权利要求书所确定的保护范围内。
Claims (6)
1.一种冷冻范围可控的精准治疗冷冻球囊导管装置，包括鞘管、冷冻球囊和回拉球囊，其特征在于，所述鞘管是弹性材料，所述冷冻球囊和所述回拉球囊均设置在所述鞘管的同一端，所述冷冻球囊与所述鞘管相接触，所述回拉球囊上设置有导杆，所述冷冻球囊上设置有导杆套，所述导杆可在所述导杆套内往复移动，所述导杆和所述导杆套均穿过所述鞘管内部；所述回拉球囊膨胀后与血管壁贴合，回撤所述回拉球囊，使所述冷冻球囊向所述鞘管方向移动，同时推动所述鞘管，使所述鞘管的末端抵住血管内壁，所述鞘管形成喇叭状结构，所述鞘管与所述冷冻球囊相接触的一端的直径较大。
2.如权利要求1所述的冷冻范围可控的精准治疗冷冻球囊导管装置，其特征在于，所述回拉球囊是受压后可膨胀的弹性材料。
3.如权利要求1所述的冷冻范围可控的精准治疗冷冻球囊导管装置，其特征在于，所述导杆设置在所述回拉球囊的轴心线上。
4.如权利要求1所述的冷冻范围可控的精准治疗冷冻球囊导管装置，其特征在于，所述导杆套设置在所述冷冻球囊的轴心线上。
5.如权利要求1所述的冷冻范围可控的精准治疗冷冻球囊导管装置，其特征在于，所述鞘管是网筒装结构。
6.如权利要求5所述的冷冻范围可控的精准治疗冷冻球囊导管装置，其特征在于，所述鞘管上设置有多个网格。
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106725838A (zh) * | 2016-02-11 | 2017-05-31 | 上海魅丽纬叶医疗科技有限公司 | 兼具球囊扩张和射频消融功能的导管及其消融方法 |
| CN109717942A (zh) * | 2017-10-31 | 2019-05-07 | 四川锦江电子科技有限公司 | 一种冷冻消融导管 |
| CN110494183A (zh) * | 2017-02-10 | 2019-11-22 | 德克萨斯医疗中心 | 用于心房间吻合术的经导管装置 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8025661B2 (en) * | 1994-09-09 | 2011-09-27 | Cardiofocus, Inc. | Coaxial catheter instruments for ablation with radiant energy |
| CA2878588A1 (en) * | 2012-07-30 | 2014-02-06 | Northwestern University | Radiofrequency probe for circumferential ablation of a hollow cavity |
| US9179973B2 (en) * | 2013-03-15 | 2015-11-10 | St. Jude Medical, Cardiology Division, Inc. | Feedback systems and methods for renal denervation utilizing balloon catheter |
| CN209360885U (zh) * | 2018-11-13 | 2019-09-10 | 上海安钛克医疗科技有限公司 | 肺静脉电隔离球囊结构 |
| CN209316044U (zh) * | 2018-11-23 | 2019-08-30 | 复旦大学附属中山医院 | 一种冷冻消融导管 |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106725838A (zh) * | 2016-02-11 | 2017-05-31 | 上海魅丽纬叶医疗科技有限公司 | 兼具球囊扩张和射频消融功能的导管及其消融方法 |
| CN110494183A (zh) * | 2017-02-10 | 2019-11-22 | 德克萨斯医疗中心 | 用于心房间吻合术的经导管装置 |
| CN109717942A (zh) * | 2017-10-31 | 2019-05-07 | 四川锦江电子科技有限公司 | 一种冷冻消融导管 |
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