CN111467455A - Traditional Chinese medicine patch for strengthening spleen and stomach and preparation method thereof - Google Patents
Traditional Chinese medicine patch for strengthening spleen and stomach and preparation method thereof Download PDFInfo
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- CN111467455A CN111467455A CN202010366630.6A CN202010366630A CN111467455A CN 111467455 A CN111467455 A CN 111467455A CN 202010366630 A CN202010366630 A CN 202010366630A CN 111467455 A CN111467455 A CN 111467455A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine patch for strengthening spleen and stomach and a preparation method thereof, wherein the traditional Chinese medicine patch comprises the following traditional Chinese medicines: poria, Atractylodis rhizoma, semen euryales, fructus Rosae Laevigatae, fructus crataegi preparata, rhizoma Atractylodis, and Curcumae rhizoma. The traditional Chinese medicine patch is suitable for preventing and/or treating infantile abdominal distension, loose stool, inappetence or hypodynamia, and has the advantages of good curative effect, simple preparation and no toxic or side effect.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine patch for strengthening spleen and stomach and a preparation method thereof.
Background
Spleen deficiency and poor appetite are the most common diseases in pediatrics, and the symptoms mainly include spleen deficiency-cold syndromes such as poor appetite, abdominal distension, discomfort and massaging preference, loose stool, enlarged tongue with teeth marks and white fur, and the like. The traditional Chinese medicine considers that the physiological characteristics of children are that the spleen is often insufficient, the spleen qi is weak, the transportation and transformation are abnormal, the diet is not thought, the spleen qi is not lifted and is weak, the food essence is transformed into qi and blood, the whole body is full of qi and blood, the sleepiness and the weakness are shown, the qi is less and the talk is not easy to talk, and the diarrhea is caused by the dysfunction of the spleen and the stomach in lifting clear and descending turbid.
The treatment of spleen deficiency and inappetence can be carried out by western medicine or traditional Chinese medicine. The western medicine treatment scheme comprises: the zinc gluconate is orally taken in consideration of the deficiency of trace element zinc in poor appetite, and probiotics treatment is given along with loose stool. The appetite can be gradually promoted by changing the dietary structure and inducing the food which is lovely eaten by the children. The traditional Chinese medicine treatment scheme is as follows: generally, under the guidance of the theory of traditional Chinese medicine, oral decoction is prepared by adopting a method of activating spleen and stimulating appetite and strengthening middle energizer, or massage and acupoint application for external treatment of children are adopted to stimulate channels and collaterals and acupoints to achieve the treatment purpose.
Patent document CN109620927A discloses a medicine for treating diarrhea due to spleen deficiency, which is prepared from poria cocos, white atractylodes rhizome stir-fried with bran and gordon euryale seed stir-fried with bran in combination with other traditional Chinese medicines, and is suitable for treating diarrhea due to spleen deficiency;
patent document CN201611228380.X discloses a medicine for treating infantile bacterial infectious diarrhea, which is prepared from fructus Rosae Laevigatae and fructus crataegi preparata in combination with other Chinese medicinal materials, and is suitable for treating infantile bacterial infectious diarrhea.
Patent document CN109248305A discloses a medicine for treating hepatic fibrosis, which is prepared from poria, rhizoma atractylodis stir-fried with bran and rhizoma zedoariae with vinegar and other traditional Chinese medicines, and is suitable for treating hepatic fibrosis, chronic liver disease and end-stage liver disease.
Patent document CN102579886A discloses a medicine for treating nephrotic syndrome, which is prepared from poria cocos, white atractylodes rhizome stir-fried with bran and cherokee rose fruit in combination with other traditional Chinese medicines, and is suitable for treating nephrotic syndrome.
Therefore, no prior art related to the combined use of poria cocos, bighead atractylodes rhizome, gordon euryale seed, cherokee rose fruit, scorched hawthorn fruit, rhizoma atractylodis and curcuma zedoary for treating spleen deficiency and inappetence is reported at present.
The present invention has been made in view of the above circumstances.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine patch for strengthening spleen and stomach, which has good curative effect, simple preparation and no toxic or side effect.
In order to realize the purpose of the invention, the invention provides a traditional Chinese medicine patch for strengthening spleen and stomach, which comprises the following traditional Chinese medicinal materials: poria, Atractylodis rhizoma, semen euryales, fructus Rosae Laevigatae, fructus crataegi preparata, rhizoma Atractylodis, and Curcumae rhizoma.
Further optionally, the rhizoma atractylodis macrocephalae is fried rhizoma atractylodis macrocephalae, and the fried rhizoma atractylodis macrocephalae is prepared by taking the rhizoma atractylodis macrocephalae as a raw material according to a processing method of Chinese pharmacopoeia.
Further optionally, the gorgon fruit is prepared from gorgon fruit fried with bran according to a processing method of Chinese pharmacopoeia.
Further optionally, the rhizoma atractylodis is fried rhizoma atractylodis, and the fried rhizoma atractylodis is prepared from the rhizoma atractylodis according to a processing method in Chinese pharmacopoeia.
Further optionally, the curcuma zedoary is vinegar-processed curcuma zedoary, and the vinegar-processed curcuma zedoary is prepared by using the curcuma zedoary as a raw material according to a processing method of Chinese pharmacopoeia.
Further optionally, the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials: poria, parched Atractylodis rhizoma, semen euryales parched with bran, fructus Rosae Laevigatae, fructus crataegi preparata, parched rhizoma Atractylodis and vinegar Curcumae rhizoma.
Further optionally, the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight: 1-3 parts of poria cocos, 1-3 parts of fried bighead atractylodes rhizome, 1-3 parts of bran-fried gordon euryale seed, 1-3 parts of cherokee rose fruit, 1-3 parts of scorched hawthorn fruit and 1-3 parts of fried rhizoma atractylodis
And 1-3 parts of vinegar curcuma zedoary.
Further optionally, the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight: 3 parts of poria cocos, 3 parts of fried bighead atractylodes rhizome, 2 parts of bran-fried gordon euryale seed, 3 parts of cherokee rose fruit, 1 part of scorched hawthorn fruit, 1 part of fried rhizoma atractylodis and 1 part of vinegar-fried curcuma zedoary.
Further optionally, the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight: 2 parts of poria cocos, 2 parts of fried bighead atractylodes rhizome, 3 parts of bran-fried gordon euryale seed, 1 part of cherokee rose fruit, 3 parts of scorched hawthorn fruit, 3 parts of fried rhizoma atractylodis and 2 parts of vinegar-fried curcuma zedoary.
Further optionally, the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight: 3 parts of poria cocos, 3 parts of fried bighead atractylodes rhizome, 2 parts of bran-fried gordon euryale seed, 2 parts of cherokee rose fruit, 3 parts of scorched hawthorn fruit, 2 parts of fried rhizoma atractylodis and 2 parts of vinegar-fried curcuma zedoary.
Further optionally, the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight: 3 parts of poria cocos, 3 parts of fried bighead atractylodes rhizome, 3 parts of bran-fried gordon euryale seed, 3 parts of cherokee rose fruit, 3 parts of scorched hawthorn fruit, 3 parts of fried rhizoma atractylodis and 3 parts of vinegar-fried curcuma zedoary.
Further optionally, the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight: 2 parts of poria cocos, 2 parts of fried bighead atractylodes rhizome, 2 parts of bran-fried gordon euryale seed, 2 parts of cherokee rose fruit, 2 parts of scorched hawthorn fruit, 2 parts of fried rhizoma atractylodis and 2 parts of vinegar-fried curcuma zedoary.
Further optionally, the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight: 1 part of tuckahoe, 1 part of fried bighead atractylodes rhizome, 1 part of bran-fried gordon euryale seed, 1 part of cherokee rose fruit, 1 part of scorched hawthorn fruit, 1 part of fried rhizoma atractylodis and 1 part of vinegar-fried curcuma zedoary.
In one specific embodiment of the invention, the traditional Chinese medicine patch is composed of the following traditional Chinese medicinal materials in parts by weight: 1-3 parts of poria cocos, 1-3 parts of fried bighead atractylodes rhizome, 1-3 parts of bran-fried gordon euryale seed, 1-3 parts of cherokee rose fruit, 1-3 parts of scorched hawthorn fruit, 1-3 parts of fried rhizoma atractylodis and 1-3 parts of vinegar curcuma zedoary.
The invention also provides a preparation method of the traditional Chinese medicine patch for strengthening spleen and stomach, which comprises the following steps:
(1) weighing the medicinal materials in parts by weight respectively;
(2) cleaning the above materials, and oven drying at 50-60 deg.C for 30-40 min;
(3) pulverizing the dried medicinal materials to 50-100 mesh, mixing, and making into powder;
(4) adding rice vinegar into the powder prepared in the step (3), and blending into paste to prepare the dressing;
(5) and placing the dressing on a carrier to prepare the patch.
Further optionally, in the step (5), a pharmaceutically acceptable adjuvant is added to the dressing and then placed on a carrier to prepare the patch. Preferably, the auxiliary material can be one or more selected from glycerol, sorbitol and stearic acid.
Further optionally, the carrier comprises at least one of a non-woven fabric, gauze, adhesive tape, plaster, or medical rubber.
The invention also provides application of the traditional Chinese medicine patch for strengthening spleen and stomach in preparation of a medicine, wherein the medicine is used for preventing and/or treating diseases of children or adults, and preferably, the diseases are selected from abdominal distension, loose stool, inappetence and hypodynamia. More preferably, the traditional Chinese medicine patch is used for treating spleen deficiency type anorexia and diarrhea.
The medicinal materials used in the invention have the following effects:
the Poria is dry sclerotium of Poria cocos (Schw.) wolf of Polyporaceae, and has sweet and light taste, and neutral nature, and it enters heart, lung, spleen, and kidney channels. Has effects in eliminating dampness, invigorating spleen, and calming heart. It is mainly used for treating edema oliguria, phlegm and fluid retention, dizziness and palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
The Atractylodis rhizoma is dried rhizome of Atractylodes macrocephala Koidz of Compositae, and has bitter, sweet and warm taste, and has effects of invigorating spleen, invigorating qi, eliminating dampness, promoting diuresis, arresting sweating, and preventing miscarriage. It is mainly used for treating diet stagnation, abdominal pain, constipation, dysentery, phlegm stagnation, and cough and asthma.
The semen euryales stir-fried with bran is dry mature seed of semen euryales of Nymphaeaceae, has sweet, astringent and neutral taste, has effects of invigorating spleen and kidney channels, benefiting kidney essence, invigorating spleen, relieving diarrhea, eliminating dampness and stopping leukorrhagia, and is mainly used for treating spermatorrhea, enuresis, frequent micturition, spleen deficiency, chronic diarrhea, whitish and turbid urine, and leukorrhagia.
The fructus Rosae Laevigatae is dried mature fruit of fructus Rosae Laevigatae of Rosaceae, and has sour, sweet, astringent and neutral taste, and can enter kidney, bladder and large intestine channels. Has the effects of securing essence and reducing urination, securing metrorrhagia and leukorrhagia, and relieving diarrhea with astringents. It is mainly used for treating spermatorrhea, enuresis, frequent micturition, metrorrhagia, leukorrhagia, chronic diarrhea, and dysentery.
The charred fructus crataegi is dried mature fruit of Crataegus pinnatifida of Rosaceae, and has sour, sweet and slightly warm taste, and can enter spleen, stomach and liver meridians. Has effects in promoting digestion, invigorating stomach, promoting qi circulation, removing blood stasis. It is mainly used for treating meat food stagnation, gastric cavity distention, dysentery abdominal pain, blood stasis amenorrhea, puerperal blood stasis, heart and abdomen stabbing pain, hernia pain, and hyperlipidemia.
The rhizoma Atractylodis is dried rhizome of Atractylodes lancea of Compositae, and has effects of eliminating dampness, invigorating spleen, dispelling pathogenic wind, dispelling cold, and improving eyesight, and it is pungent, bitter, warm, and has effects of invigorating spleen, stomach, and liver channel. It is mainly used for treating abdominal distention, diarrhea, edema, rheumatalgia, wind-cold type common cold, and nyctalopia.
The Curcumae rhizoma is dried rhizome of Curcumae rhizoma of Zingiberaceae, and has pungent, bitter, and warm taste, and enters liver and spleen channels. Has the effects of breaking blood, promoting qi circulation, removing food retention, and relieving pain. Is mainly used for treating blood-qi and heart pain, food stagnation, abdominal distention and pain, blood stagnation and amenorrhea, dysmenorrhea, abdominal mass and lump, and traumatic injury.
Based on the clinical experience of the traditional Chinese medicine for many years, the inventor of the invention deeply researches the pathogenesis of diseases such as anorexia and diarrhea caused by spleen deficiency of children, thinks that the disease is located in the spleen and the stomach, which is the acquired root, the stomach is controlled to accept and is transported and transformed by the spleen, and the coordination of the spleen and the stomach indicates hunger, desire to eat and can be transformed by eating. The common causes include improper feeding, damp-heat in spleen and stomach, spleen injury due to other diseases, deficient innate endowment and emotional disorder, which can damage the normal transportation and transformation functions of spleen and stomach, resulting in spleen deficiency and anorexia. Aiming at the etiology and pathogenesis, the treatment principle is as follows: activate the spleen, stimulate the appetite, strengthen the middle energizer. The invention combines and prepares a patch for treating anorexia and diarrhea caused by spleen deficiency by combining a plurality of Chinese medicinal materials including tuckahoe, atractylodes, gordon euryale seed, cherokee rose fruit, scorched hawthorn fruit, rhizoma atractylodis and zedoary; the idea of the formula is as follows: rhizoma atractylodis is taken as a monarch drug, and has the functions of eliminating dampness, strengthening spleen and warming middle-jiao; largehead atractylodes rhizome and Indian buead are taken as ministerial drugs and assistant drugs for invigorating spleen and relieving diarrhea; semen euryales, hawthorn and fructus rosae laevigatae are used as adjuvant drugs, and the emphasis is on astringency and astringency to regulate the bowels; zedoary is used as a guiding drug to avoid the stagnation of all the drugs. The traditional Chinese medicine patch combines and uses the tuckahoe, the white atractylodes rhizome, the gordon euryale seed, the cherokee rose fruit, the scorched hawthorn fruit, the rhizoma atractylodis and the zedoary, and fully exerts the drug effect of each component by utilizing the interaction relationship of monarch, minister, assistant and guide among each drug component.
The traditional Chinese medicine patch is used for treating anorexia, diarrhea and other diseases caused by spleen deficiency by adopting an external application mode, and the specific use method comprises the following steps: the traditional Chinese medicine patch is pasted on the Shenque acupoint for two hours every day, one treatment course is 7 days, and good curative effect can be obtained after four treatment courses are continuously used.
Compared with the prior art, the invention has the beneficial effects that:
has good curative effect on children with anorexia and diarrhea, reasonable formula, no toxic or side effect, safe and reliable curative effect, is suitable for infants and children, can enhance the immunologic function, and avoids the pain of injection and transfusion.
Detailed Description
The present invention is further described in the following description of the specific embodiments, which is not intended to limit the invention, but various modifications and improvements can be made by those skilled in the art according to the basic idea of the invention, within the scope of the invention, as long as they do not depart from the basic idea of the invention.
Example 1
(1) Taking 3 parts by weight of poria cocos, 3 parts by weight of fried bighead atractylodes rhizome, 2 parts by weight of bran-fried gordon euryale seed, 2 parts by weight of cherokee rose fruit, 3 parts by weight of scorched hawthorn fruit, 2 parts by weight of fried rhizoma atractylodis and 2 parts by weight of vinegar curcuma zedoary;
(2) cleaning the Chinese medicinal materials, and drying by a dryer at 50 deg.C for 40 min;
(3) pulverizing the dried Chinese medicinal materials, pulverizing to 80 mesh, mixing, and making into powder;
(4) adding rice vinegar into the powder prepared in the step (3), and blending into paste to prepare the dressing;
(5) and placing the dressing on a carrier to prepare the patch.
Wherein: the fried rhizoma atractylodis macrocephalae is directly purchased or is prepared by processing rhizoma atractylodis macrocephalae according to the legal processing method of Chinese pharmacopoeia; the gordon euryale seed fried with bran is obtained by direct purchase or is prepared according to the legal processing method of Chinese pharmacopoeia; the parched rhizoma Atractylodis is obtained directly or prepared according to the legal processing method of Chinese pharmacopoeia; the vinegar-processed rhizoma Curcumae is obtained by directly purchasing, or processing rhizoma Curcumae according to the legal processing method of Chinese pharmacopoeia.
Examples 2 to 7
Examples 2-7 are the preparation of the Chinese medicinal patch according to the preparation of example 1, the pharmaceutical components and process conditions shown in Table I.
Table one: the components of the Chinese traditional medicines in examples 2-7 and the process conditions
Test examples
The experimental example is a clinical study on the aspect of treating infantile spleen deficiency and inappetence by using the traditional Chinese medicine patch prepared in example 1.
1. Case selection
Randomly selecting 100 children patients with spleen deficiency type inappetence in Beijing Huimin traditional Chinese medicine children hospital, wherein the average age of the children patients is 5 years old and 6 months, the male-female ratio is 1:1, and the diagnosis basis is as follows: two or more symptoms of abdominal distension, loose stool, inappetence and hypodynamia appear, the duration lasts for one week or more and is not more than four weeks, and no improvement is seen. According to the degree of the symptoms, the children patients are classified into four grades of mild, severe and severe, and the specific classification standard is shown in the table two:
table two: grading standard of disease symptoms of children patients
2. Method of treatment
The patch prepared in example 1 is applied to the Shenque point of a child patient once a day, two hours each time, 7 days as a treatment course, and four treatment courses are continuously observed.
3. Observation index
All children patients are observed and counted according to a unified scientific research design, and are researched in a self-front-back comparison mode. And (5) adopting a classification statistical method, and setting 10 classifications of improvement conditions of each symptom from weak to strong.
Appetite improvement: the food intake is the same as that before (0 min), the food intake is slightly increased (1-5 min) and obviously improved (6-10 min); abdominal discomfort conditions: no obvious change (score 0), slight decrease of pain frequency or duration (score 1-5), and obvious decrease (score 6-10); stool improvement: no change (0 min), reduced stool frequency or improved soft stool character (1-5 min), moderate soft stool character (6-10 min) for 1-2 times per day;
the diagnosis and treatment conditions of the children patients at different levels after the medicine is taken are divided into invalid, effective and recovery, wherein the total score is 0, 1-15, 16-18 and 19-30, respectively.
4. The results of clinical experiments are shown in table three.
TABLE III clinical test results after drug administration for children patients
| Number of cases before administration | Number of cure cases | Number of effective cases | Effective number of cases | Number of invalid cases | |
| Light and slight | 30 | 6 | 15 | 9 | 0 |
| Is lighter | 55 | 11 | 23 | 20 | 1 |
| Heavy weight | 8 | 2 | 4 | 1 | 1 |
| Severe severity of disease | 7 | 1 | 3 | 1 | 2 |
After four courses of treatment, most of the children patients meet the effective curative effect standard, and no obvious adverse reaction is found in the treatment process.
5. Case analysis
Case one: the infant patient is 4 years old, the gender is female, the appetite of the infant patient is poor in nearly one month, umbilical pain occurs sometimes, stool is dry and irregular, sleeping is uneasy to lie prone, teeth are ground, peculiar smell occurs in morning, the face is white, the tongue body is fat and large, the coating is white and thick, and the fingerprint is hidden and slightly purple. After one week of the application treatment, the symptoms are better, the pain around the umbilicus is relieved, the appetite is increased, and the stool is not shaped occasionally. After being continuously applied for two weeks, the appetite is obviously improved, and the symptom of insomnia and uneasiness at night is improved. After four weeks the symptoms had disappeared completely.
Case two: the patient is 7 years old, and male with sex has symptoms of poor appetite, easy abdominal distension, hypodynamia, mental confusion, light weight and loose stool. After being pasted and treated for two weeks, the Chinese medicinal preparation has the advantages of good symptom, no abdominal distension, appetite increase and occasional loose stool. After two weeks of continued treatment, the symptoms essentially disappeared and appetite improved.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A traditional Chinese medicine patch for strengthening spleen and stomach is characterized by comprising the following traditional Chinese medicine materials: poria, Atractylodis rhizoma, semen euryales, fructus Rosae Laevigatae, fructus crataegi preparata, rhizoma Atractylodis, and Curcumae rhizoma.
2. The traditional Chinese medicine patch for strengthening spleen and stomach according to claim 1, wherein the traditional Chinese medicine patch comprises the following traditional Chinese medicines: poria, parched Atractylodis rhizoma, semen euryales parched with bran, fructus Rosae Laevigatae, fructus crataegi preparata, parched rhizoma Atractylodis and vinegar Curcumae rhizoma.
3. The traditional Chinese medicine patch for strengthening spleen and stomach according to claim 2, characterized in that the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight:
4. the traditional Chinese medicine patch for strengthening spleen and stomach according to claim 2, characterized in that the traditional Chinese medicine patch comprises the following traditional Chinese medicinal materials in parts by weight:
5. the traditional Chinese medicine patch for strengthening spleen and stomach according to claim 1, wherein the traditional Chinese medicine patch is composed of the following traditional Chinese medicinal materials in parts by weight:
6. a method of preparing a spleen and stomach strengthening traditional Chinese medicine patch according to any one of claims 1-5, characterized in that the preparation method comprises the following steps:
(1) weighing the medicinal materials in parts by weight respectively;
(2) cleaning the above materials, and oven drying at 50-60 deg.C for 30-40 min;
(3) pulverizing the dried medicinal materials to 50-100 mesh, mixing, and making into powder;
(4) adding rice vinegar into the powder prepared in the step (3), and blending into paste to prepare the dressing;
(5) and placing the dressing on a carrier to prepare the patch.
7. The preparation method according to claim 6, wherein in the step (5), the dressing is added with pharmaceutically acceptable auxiliary materials and then placed on a carrier to prepare the patch.
8. The method of claim 6 or 7, wherein the carrier comprises at least one of a non-woven fabric, gauze, adhesive tape, plaster, or medical rubber.
9. Use of a traditional Chinese medicine patch according to any one of claims 1 to 5 for the preparation of a medicament for the prevention and/or treatment of pediatric disorders selected from the group consisting of abdominal distension, loose stool, loss of appetite or lack of strength.
10. Use of a traditional Chinese medicine patch according to any one of claims 1 to 5 for the preparation of a medicament for the prevention and/or treatment of a pediatric disorder selected from the group consisting of anorexia due to spleen deficiency, diarrhea.
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| CN104127795A (en) * | 2014-08-14 | 2014-11-05 | 吴荣梅 | Children patch for strengthening spleen and stomach |
| CN104800327A (en) * | 2015-05-11 | 2015-07-29 | 张先雷 | Navel paste for treating infant autumn diarrhea |
| CN109771602A (en) * | 2019-03-07 | 2019-05-21 | 张春梅 | For treating external application type Traditional Chinese medicine composition patch, preparation and its application of diarrhea |
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2020
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| CN104127795A (en) * | 2014-08-14 | 2014-11-05 | 吴荣梅 | Children patch for strengthening spleen and stomach |
| CN104800327A (en) * | 2015-05-11 | 2015-07-29 | 张先雷 | Navel paste for treating infant autumn diarrhea |
| CN109771602A (en) * | 2019-03-07 | 2019-05-21 | 张春梅 | For treating external application type Traditional Chinese medicine composition patch, preparation and its application of diarrhea |
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