CN111466997A - Thrombolytic device for promoting drug absorption by using ultrasonic waves - Google Patents
Thrombolytic device for promoting drug absorption by using ultrasonic waves Download PDFInfo
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- CN111466997A CN111466997A CN202010463349.4A CN202010463349A CN111466997A CN 111466997 A CN111466997 A CN 111466997A CN 202010463349 A CN202010463349 A CN 202010463349A CN 111466997 A CN111466997 A CN 111466997A
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- 239000003814 drug Substances 0.000 title claims abstract description 84
- 229940079593 drug Drugs 0.000 title claims abstract description 72
- 230000002537 thrombolytic effect Effects 0.000 title claims abstract description 53
- 239000003146 anticoagulant agent Substances 0.000 title claims abstract description 30
- 238000010521 absorption reaction Methods 0.000 title claims abstract description 29
- 230000001737 promoting effect Effects 0.000 title abstract description 18
- 238000002604 ultrasonography Methods 0.000 claims description 17
- 239000008280 blood Substances 0.000 claims description 4
- 210000004369 blood Anatomy 0.000 claims description 4
- 238000012377 drug delivery Methods 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 208000007536 Thrombosis Diseases 0.000 abstract description 21
- 230000000694 effects Effects 0.000 abstract description 12
- 230000002792 vascular Effects 0.000 abstract description 9
- 238000004090 dissolution Methods 0.000 abstract description 3
- 230000035515 penetration Effects 0.000 abstract 1
- 239000003527 fibrinolytic agent Substances 0.000 description 9
- 238000001727 in vivo Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000008719 thickening Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 239000002872 contrast media Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000009210 therapy by ultrasound Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
- A61B2017/22045—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire fixed to the catheter; guiding tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
- A61B2017/22084—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance stone- or thrombus-dissolving
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
- A61B2017/22088—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance ultrasound absorbing, drug activated by ultrasound
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Mechanical Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The invention discloses a thrombolytic device for promoting drug absorption by using ultrasonic waves, and belongs to the technical field of medical instruments. The thrombolytic device for promoting drug absorption by using ultrasonic waves comprises an operating handle, a drug release catheter and an ultrasonic waveguide wire; the operating handle is fixedly connected with the drug release catheter through a luer connector; the operating handle consists of a shell, an ultrasonic generator, an ultrasonic transducer, a battery, an ultrasonic switch and an ultrasonic adjusting knob. The thrombolysis device for promoting drug absorption by using ultrasonic waves carries out continuous ultrasonic cavitation treatment on the thrombolysis drug at the thrombus part, thereby greatly promoting the penetration and dissolution of the thrombolysis drug on thrombus; and this device ultrasonic wave guide silk is located inside the medicine release pipe, does not contact with the vascular wall, can not harm vascular wall and surrounding tissue. The thrombolysis device for promoting drug absorption by using ultrasonic waves is used for removing thrombus and has the advantages of good thrombolysis effect, short treatment time, simple operation, safety, reliability and the like.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a thrombolytic device for promoting drug absorption by using ultrasonic waves.
Background
Catheter thrombolysis is effective in treating vascular thrombosis and has become widely accepted and entered clinical guidelines. Catheter thrombolysis most commonly involves placing a drug-releasing catheter in the area of the thrombus and directly infusing thrombolysis drug through the catheter to achieve thrombolysis, which often requires the catheter to be left in the body for several days due to the slow action of thrombolysis drug and thrombus. The prolonged treatment time results in prolonged patient hospitalization and an increased risk of catheter thrombolysis complications. Therefore, the method has important clinical value for improving the thrombolytic efficiency of the medicine and shortening the thrombolytic time.
The role of ultrasonic thrombolysis in thrombus treatment is more and more attracting attention of people, and the ultrasonic thrombolysis is mainly divided into in vitro ultrasonic and in vivo ultrasonic according to the action position of ultrasonic. Research shows that in vitro therapeutic ultrasound (ETUS) assisted thrombolysis can utilize the cavitation effect of ultrasound, so that thrombolytic drugs can enter the interior of thrombus more and more quickly to play a role, and the drug thrombolysis effect is enhanced. The method has the disadvantages that the parameters such as the optimal ultrasonic frequency, the sound intensity and the like of thrombus at different parts in vivo need to be researched by large-scale clinical research because the external ultrasonic wave attenuates when passing through the tissues of the human body and the attenuation degree is different along with the passing tissues. The ultrasonic treatment in vivo utilizes the mechanical vibration effect of the ultrasound, the thrombus removal effect is good, but the thrombus removal effect can be achieved only by adopting high-frequency ultrasound, and the side effect is large.
Disclosure of Invention
The invention aims to provide a thrombolysis device for promoting drug absorption by using ultrasonic waves, which solves the problems of complex ultrasonic parameter adjustment and great ultrasonic side effect in the traditional mode of enhancing the thrombolysis effect by using the ultrasonic cavitation effect.
In order to solve the technical problems, the invention provides a thrombolytic device for promoting drug absorption by using ultrasonic waves, which comprises an operating handle, a drug release catheter and an ultrasonic waveguide wire;
the operating handle is fixedly connected with the drug release catheter through a luer connector;
the operating handle consists of a shell, an ultrasonic generator, an ultrasonic transducer, a battery, an ultrasonic switch and an ultrasonic adjusting knob;
the battery, the ultrasonic generator and the ultrasonic transducer are sequentially connected;
the ultrasonic wave guide wire penetrates through the drug release catheter and the luer connector to be welded with the ultrasonic wave transducer.
Optionally, the front end of the ultrasonic waveguide wire is provided with an ultrasonic release thickening end, so that the ultrasonic emission surface area can be increased.
Optionally, the top end of the ultrasonic guide wire is fixedly connected with a spring contact end, and the spring contact end extends out from the top end of the drug release catheter to provide tactile feedback.
Optionally, the end of the drug release catheter is provided with a Y-shaped multi-way tube, and the Y-shaped multi-way tube is respectively composed of an ultrasonic waveguide thread inlet and a liquid medicine inlet.
Optionally, a blood backflow prevention sealing ring is arranged in the ultrasonic waveguide thread inlet.
Optionally, a plurality of micropores are uniformly distributed on the side wall of the front end of the drug release catheter, the micropores are longitudinally arranged rectangular holes, and the longitudinal section of the catheter wall is of a negative cone structure.
Optionally, a plurality of said micropores are arranged at equal intervals along the circumference of said drug release catheter.
Optionally, a plurality of said micropores are arranged at equal intervals along the longitudinal direction of said drug release catheter.
Optionally, the top end of the drug release catheter is a hollow conical head.
Optionally, the ultrasonic switch is a push switch, and is fixedly mounted on the side wall of the housing and used for controlling the on-off of the ultrasonic generator; the ultrasonic adjusting knob is a knob type switch and is fixedly arranged on the side wall of the shell and used for adjusting ultrasonic frequency.
The invention provides a thrombolytic device for promoting drug absorption by using ultrasonic waves, which comprises an operating handle, a drug release catheter and an ultrasonic waveguide wire; the operating handle is fixedly connected with the drug release catheter through a luer connector; the operating handle consists of a shell, an ultrasonic generator, an ultrasonic transducer, a battery, an ultrasonic switch and an ultrasonic adjusting knob; the battery, the ultrasonic generator and the ultrasonic transducer are sequentially connected; the ultrasonic wave guide wire penetrates through the drug release catheter and the luer connector to be welded with the ultrasonic wave transducer. The thrombolytic device for promoting drug absorption by using ultrasonic waves is internally provided with the thrombolytic device for promoting drug absorption by using ultrasonic waves, continuous ultrasonic cavitation treatment is directly carried out on the thrombolytic drug at a thrombus part, and the permeation and dissolution of the thrombolytic drug to thrombus are greatly promoted; and this device ultrasonic wave guide silk is located inside the medicine release pipe, does not contact with the vascular wall, can not harm vascular wall and surrounding tissue. The thrombolysis device for promoting drug absorption by using ultrasonic waves is used for removing thrombus and has the advantages of good thrombolysis effect, short treatment time, simple operation, safety, reliability and the like.
Drawings
FIG. 1 is a schematic diagram illustrating the overall structure of a thrombolytic device using ultrasound to promote drug absorption according to the present invention;
FIG. 2 is a schematic view showing the internal structure of an operation handle of a thrombolytic device using ultrasonic waves to promote drug absorption according to the present invention;
FIG. 3 is a schematic diagram of the tip structure of an ultrasonic waveguide wire of a thrombolytic device using ultrasonic waves to promote drug absorption according to the present invention;
FIG. 4 is a schematic structural view of a drug delivery catheter of a thrombolytic device using ultrasound to promote drug absorption according to the present invention;
fig. 5 is a partially enlarged view of a drug delivery catheter of a thrombolytic device using ultrasound to promote drug absorption according to the present invention.
Detailed Description
The thrombolytic device using ultrasound to promote drug absorption according to the present invention will be described in further detail with reference to the accompanying drawings and specific examples. Advantages and features of the present invention will become apparent from the following description and from the claims. It is to be noted that the drawings are in a very simplified form and are not to precise scale, which is merely for the purpose of facilitating and distinctly claiming the embodiments of the present invention.
Example one
The invention provides a thrombolytic device for promoting drug absorption by using ultrasonic waves, which is structurally shown in figures 1 and 2 and comprises an operating handle 1, a drug release catheter 2 and an ultrasonic waveguide wire 3; the operating handle 1 is fixedly connected with the drug release catheter 2 through a luer connector 4; the operating handle 1 consists of a shell 11, an ultrasonic generator 12, an ultrasonic transducer 13, a battery 14, an ultrasonic switch 15 and an ultrasonic adjusting knob 16; the battery 14, the ultrasonic generator 12 and the ultrasonic transducer 13 are connected in sequence; the ultrasonic wave guide wire 3 passes through the drug release catheter 2 and the luer 4 to be welded with the ultrasonic wave transducer 13.
Specifically, as shown in fig. 3, the front end of the ultrasonic waveguide wire 3 is provided with an ultrasonic wave releasing thickened end 31, which can increase the ultrasonic wave emission surface area; the top end of the ultrasonic wave guide wire 3 is fixedly connected with a spring contact end 32, and the spring contact end 32 extends out of the top end of the drug release catheter 2 to provide tactile feedback.
Specifically, as shown in fig. 4, a Y-shaped multi-way tube is arranged at the end of the drug release catheter 2, and the Y-shaped multi-way tube is respectively composed of an ultrasonic waveguide thread inlet 21 and a drug solution inlet 22; a blood backflow prevention sealing ring 23 is arranged in the ultrasonic waveguide thread inlet 21, so that blood backflow can be prevented; a plurality of micropores 24 are uniformly distributed on the side wall of the front end of the drug release catheter 2, the micropores 24 are rectangular holes which are longitudinally arranged, and the longitudinal section of the catheter wall is of a negative cone structure, as shown in fig. 5; the plurality of micropores 24 are arranged at equal intervals along the circumference of the drug release catheter 2, and the plurality of micropores 24 are arranged at equal intervals along the longitudinal direction of the drug release catheter 2; the top end of the drug release catheter 2 is a hollow conical head 25, the spring contact end 32 extends out of the hollow conical head 25, and the ultrasonic release thickening end 31 plugs the hollow conical head 25; the ultrasonic switch 15 is a push switch, is fixedly mounted on the side wall of the housing 11, and is used for controlling the start and stop of the ultrasonic generator 12; the ultrasonic adjusting knob 16 is a knob switch, fixedly mounted on the side wall of the housing 11, and used for adjusting ultrasonic frequency.
Specifically, when a patient is subjected to a thrombolysis operation, a common guide wire is firstly used for vascular intervention to reach a vascular thrombus area, and the drug release catheter 2 is implanted; then, a contrast medium is poured into the liquid medicine inlet 22 of the Y-shaped multi-way tube at the proximal end of the medicine release catheter 2, the position of a developing ring at the distal end of the medicine release catheter 2 is observed, the developing ring is positioned at two sides of thrombus, a common guide wire is pulled out, the ultrasonic guide wire 3 is implanted, the spring contact end 32 guides the ultrasonic release thickened end 31 to enter the top end of the medicine release catheter 2 through the top end of the medicine release catheter 2, and the hollow conical head 25 at the top end of the medicine release catheter 2 is plugged; then, thrombolytic drugs are infused from the liquid medicine inlet 22 of the Y-shaped multi-way tube, and the thrombolytic drugs are released into thrombus from a plurality of micropores 24 at the front end of the drug release catheter 2 due to the blockage of the top end of the drug release catheter 2; finally, the ultrasonic switch 15 is turned on, the ultrasonic generator 12 emits ultrasonic waves, the ultrasonic wave is adjusted by the ultrasonic adjusting knob 16 to generate low-frequency ultrasonic waves, the ultrasonic transducer 13 converts the ultrasonic waves into mechanical vibration, the mechanical vibration is transmitted to the ultrasonic release thickening end 31 through the ultrasonic waveguide wire 3, and thrombolytic drugs are continuously cavitated; the cavitated thrombolytic drug is released into the thrombus from the micropores of the drug release catheter for thrombolysis. The thrombolytic device for promoting drug absorption by using ultrasonic waves is internally provided with the thrombolytic device for promoting drug absorption by using ultrasonic waves, continuous ultrasonic cavitation treatment is directly carried out on the thrombolytic drug at a thrombus part, and the permeation and dissolution of the thrombolytic drug to thrombus are greatly promoted; and this device ultrasonic wave guide silk is located inside the medicine release pipe, does not contact with the vascular wall, can not harm vascular wall and surrounding tissue. The thrombolysis device for promoting drug absorption by using ultrasonic waves is used for removing thrombus and has the advantages of good thrombolysis effect, short treatment time, simple operation, safety, reliability and the like.
The above description is only for the purpose of describing the preferred embodiments of the present invention, and is not intended to limit the scope of the present invention, and any variations and modifications made by those skilled in the art based on the above disclosure are within the scope of the appended claims.
Claims (10)
1. A thrombolytic device using ultrasonic waves to promote drug absorption, comprising an operation handle (1), a drug release catheter (2) and an ultrasonic waveguide wire (3);
the operating handle (1) is fixedly connected with the drug release catheter (2) through a luer connector (4);
the operating handle (1) consists of a shell (11), an ultrasonic generator (12), an ultrasonic transducer (13), a battery (14), an ultrasonic switch (15) and an ultrasonic adjusting knob (16);
the battery (14), the ultrasonic generator (12) and the ultrasonic transducer (13) are connected in sequence;
the ultrasonic wave guide wire (3) penetrates through the drug release catheter (2) and the luer connector (4) to be welded with the ultrasonic wave transducer (13).
2. The thrombolytic device of claim 1, wherein the ultrasound wave guide wire (3) has an ultrasound wave releasing enlarged end (31) at the front end thereof to increase the ultrasound wave emitting surface area.
3. A thrombolytic device using ultrasound to facilitate drug absorption according to claim 1, wherein a spring contact end (32) is fixedly attached to the tip of the ultrasound waveguide wire (3), and the spring contact end (32) extends from the tip of the drug release catheter (2) to provide tactile feedback.
4. The thrombolytic device of claim 1, wherein the drug release catheter (2) is terminated with a Y-manifold consisting of an ultrasound guide wire inlet (21) and a drug solution inlet (22), respectively.
5. A thrombolytic device using ultrasound to facilitate drug absorption according to claim 4, wherein a blood backflow preventing sealing ring (23) is provided in the ultrasound waveguide thread inlet (21).
6. The thrombolytic device of claim 1, wherein the drug release catheter (2) has a plurality of micropores (24) uniformly distributed on the side wall of the front end, the micropores (24) are longitudinally arranged rectangular holes, and the longitudinal section of the catheter wall has a negative cone structure.
7. A thrombolytic device using ultrasound to facilitate drug absorption according to claim 6, wherein a plurality of the micropores (24) are arranged at equal intervals along the circumference of the drug delivery catheter (2).
8. A thrombolytic device using ultrasonic waves to facilitate drug absorption according to claim 6, wherein a plurality of the micropores (24) are arranged at equal intervals in the longitudinal direction of the drug releasing catheter (2).
9. The thrombolytic device of claim 1, wherein the drug releasing catheter (2) has a hollow conical tip (25) at its tip.
10. The thrombolytic device using ultrasonic waves to promote drug absorption according to claim 1, wherein the ultrasonic switch (15) is a push-type switch fixedly mounted on the side wall of the housing (11) for controlling the on-off of the ultrasonic generator (12); the ultrasonic adjusting knob (16) is a knob type switch and is fixedly arranged on the side wall of the shell (11) and used for adjusting ultrasonic frequency.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010463349.4A CN111466997A (en) | 2020-05-27 | 2020-05-27 | Thrombolytic device for promoting drug absorption by using ultrasonic waves |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010463349.4A CN111466997A (en) | 2020-05-27 | 2020-05-27 | Thrombolytic device for promoting drug absorption by using ultrasonic waves |
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| CN111466997A true CN111466997A (en) | 2020-07-31 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111820992A (en) * | 2020-08-17 | 2020-10-27 | 北京华脉泰科医疗器械有限公司 | Thrombolytic catheter device |
| CN113995470A (en) * | 2021-10-26 | 2022-02-01 | 广东博迈医疗科技股份有限公司 | Medical interventional aspiration catheter |
| CN115429382A (en) * | 2022-09-01 | 2022-12-06 | 上海腾复医疗科技有限公司 | Thrombolysis device |
| CN118526257A (en) * | 2024-07-10 | 2024-08-23 | 重庆市急救医疗中心 | Ultrasonic drainage tube with promote medicine dispersion |
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| US6689086B1 (en) * | 1994-10-27 | 2004-02-10 | Advanced Cardiovascular Systems, Inc. | Method of using a catheter for delivery of ultrasonic energy and medicament |
| CN203379185U (en) * | 2013-06-04 | 2014-01-08 | 加奇生物科技(上海)有限公司 | Intracranial thrombus removing device |
| CN108187183A (en) * | 2017-12-22 | 2018-06-22 | 中国船舶重工集团公司第七〇五研究所 | A kind of built-in medical supersonic thromboembolism treatment instrument |
| CN212234582U (en) * | 2020-05-27 | 2020-12-29 | 江苏金泰医疗器械有限公司 | Ultrasonic thrombolysis device |
-
2020
- 2020-05-27 CN CN202010463349.4A patent/CN111466997A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6689086B1 (en) * | 1994-10-27 | 2004-02-10 | Advanced Cardiovascular Systems, Inc. | Method of using a catheter for delivery of ultrasonic energy and medicament |
| CN203379185U (en) * | 2013-06-04 | 2014-01-08 | 加奇生物科技(上海)有限公司 | Intracranial thrombus removing device |
| CN108187183A (en) * | 2017-12-22 | 2018-06-22 | 中国船舶重工集团公司第七〇五研究所 | A kind of built-in medical supersonic thromboembolism treatment instrument |
| CN212234582U (en) * | 2020-05-27 | 2020-12-29 | 江苏金泰医疗器械有限公司 | Ultrasonic thrombolysis device |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111820992A (en) * | 2020-08-17 | 2020-10-27 | 北京华脉泰科医疗器械有限公司 | Thrombolytic catheter device |
| CN113995470A (en) * | 2021-10-26 | 2022-02-01 | 广东博迈医疗科技股份有限公司 | Medical interventional aspiration catheter |
| CN115429382A (en) * | 2022-09-01 | 2022-12-06 | 上海腾复医疗科技有限公司 | Thrombolysis device |
| CN115429382B (en) * | 2022-09-01 | 2023-11-03 | 上海腾复医疗科技有限公司 | Thrombolysis device |
| WO2024045386A1 (en) * | 2022-09-01 | 2024-03-07 | 上海腾复医疗科技有限公司 | Thrombolytic apparatus |
| CN118526257A (en) * | 2024-07-10 | 2024-08-23 | 重庆市急救医疗中心 | Ultrasonic drainage tube with promote medicine dispersion |
| CN118526257B (en) * | 2024-07-10 | 2024-10-22 | 重庆市急救医疗中心 | Ultrasonic drainage tube with promote medicine dispersion |
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