CN1114584A - Medicine for tonifying brain and raising intelligence - Google Patents
Medicine for tonifying brain and raising intelligence Download PDFInfo
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- CN1114584A CN1114584A CN 95106738 CN95106738A CN1114584A CN 1114584 A CN1114584 A CN 1114584A CN 95106738 CN95106738 CN 95106738 CN 95106738 A CN95106738 A CN 95106738A CN 1114584 A CN1114584 A CN 1114584A
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Abstract
The present invention provides a pure natural medicine capable of tonifying brain, raising-intelligence and curing intellectual disturbance syndrome of middle school student and its production method. The main ingredients of said medicine are: 10-15g of ginseng, 15-30g of astragalus root, 10-18g of longan aril, 10-15g of poria, 12-18g of white peony root, 10-15g of polygala root, 10-15g of pueraria root, 6-10g of phellodendron bark, 10-18g of grassleaved sweetflag rhizome, 4-6g of cimicifuga rhizome, 5-10g of liquorice and 10-24g of Fructus viticis.
Description
The present invention is a kind of Chinese medicine of brain healthy, and a kind of energy of more specifically saying so improves human IQ, particularly treats middle school student's dysnoesia syndrome, improves the teenager brain function, promotes its intelligence, does not have any artificial additives's pure natural property medicine.
Motherland's medical science thinks whether the height of IQ normally has substantial connection, the especially heart with human five internal organs's function, spleen, and the kidney relation is very close.Says as " Ling Shu Miraculous Pivot or Divine Axis, big puzzled opinion ": " people's forgetful person, only does it make so? fork uncle day: QI of the upper portion of the body being insufficient, the therapeutic method to keep the adverse QI flowing downwards is had a surplus, and the intestines and stomach is had a guilty conscience in fact, and void is then sought to defend and stayed, and is of a specified duration not with to last, so also forgetful." the Zhang Jingyue cloud: " and naivete and being insomnia, must the ying-qi deficiency also, seek main blood, blood is difficult to nourish heart, the then mental derangement of having a guilty conscience." Cheng Guopeng says in " medical science innermost thoughts and feelings ": " kidney master intelligence, heart storing spirit are suffered from a deficiency of the kidney then the intelligence deficiency also." leaf sky scholar's cloud: " the then long intelligence of strengthening the spleen " or the like.
Over the past thousands of years, human carry out unremitting effort for the mental intelligence of improving self, particularly made many work aspect the teenager brain healthy making.For example: doctor Chen Bin is in 38-39 pages of data of having introduced fixed intelligent pill for curing middle school student syndrome 63 examples of relevant production Fructus Alpiniae Oxyphyllae of " communication of traditional Chinese medical science correspondence course " the tenth first phase in 1992.
The inventor thinks that according to a large amount of documents and materials and long-term observation the main pathology of middle school student's dysnoesia syndrome is heart deficiency of spleen-QI, deficiency of kidney-essence, and the temperament and interest uneasiness that causes, the five internal organs do not conform to and cause.At this pathological change, on the basis of " deciding the intelligence ball " two ancient prescriptions in the Thousand Golden Prescriptions that Mr. Sun Simiao of our " yiqi clever soup " in " eastern wall ten books " that gold dollar epoch Mr. Li Dongyuan is shown and the Tang Dynasty is shown, in conjunction with the long-term clinical practice experience, find out the brand-new natural drug composition that is different from above original technology.
The Chinese patent medicine that the purpose of this invention is to provide a kind of brand-new nourishing the brain and improving intelligence.
Another object of the present invention provides a kind of pure natural medical of brand-new treatment middle school student dysnoesia syndrome.
A further object of the present invention provides the preparation brain healthy, the method for the pure natural medical combination of treatment middle school student dysnoesia syndrome.
A further object of the invention provides the application method of pharmaceutical composition of the present invention.
It is as follows that pharmaceutical composition of the present invention constitutes proportioning: Radix Ginseng 5-10g Radix Astragali 15-30g Arillus Longan 10-18g Poria 10-15g Radix Paeoniae Alba 12-18g Radix Polygalae 10-15g Radix Puerariae 10-15g Cortex Phellodendri 6-10g Rhizoma Acori Graminei 10-18g Rhizoma Cimicifugae 4-6g Radix Glycyrrhizae 5-10g Fructus Viticis 10-24g
The Fang Zhongyong Radix Ginseng, Radix Astragali temperature compensation heart spleen, the lucid yang sending up gas, fortune blood, the two is monarch drug altogether, the sweet temperature heart-spleen boosting of Arillus Longan, QI invigorating and calming the nerves; Poria, Radix Polygalae, the Cortex Phellodendri restoring normal coordination between the heart and kidney, hard kidney tonifying YIN, the Fructus Alpiniae Oxyphyllae of calming the nerves is a ministerial drug; The Radix Paeoniae Alba is nourished blood for making yin fluid astringing and blood; Radix Puerariae, Fructus Viticis, Rhizoma Cimicifugae lightly float, and to rise occurring in YANG part of the body bright, and vigour rises in the taste and draw, and is adjuvant drug with solid the foundation of acquired constitution; Rhizoma Acori Graminei is calmed the nerves and is had one's ideas straightened out, the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.More than each flavor share and play replenishing QI to invigorate the spleen altogether, tranquilizing by nourishing the heart, the effect of kidney-tonifying and brain tonic.
The present invention is preferred composed as follows:
Radix Ginseng 8-10g Radix Astragali 25-30g Arillus Longan 15-18g
Poria 10-12g Radix Paeoniae Alba 12-15g Radix Polygalae 10-12g
Radix Puerariae 10-12g Cortex Phellodendri 6-8g Rhizoma Acori Graminei 15-18g
Rhizoma Cimicifugae 4-6g Radix Glycyrrhizae 5-10g Fructus Viticis 10-15g
The used above-mentioned various Chinese crude drugs of the present invention are the kind that Chinese Pharmacopoeia nineteen ninety version is recorded, and according to pharmacopeia quality of medicinal material control are carried out in the requirement of each kind respectively.
Compositions of the present invention both can be made into decoction and oral liquid, can be made into the extractum coated tablet again, also can be made into soft capsule.Both can not add any inert additwe, filler etc. also can add an amount of natural bulking agent, filler, Mel for example, Icing Sugar, white dextrin, calcium carbonate, carbon fat acid, arabic gum, gelatin etc.
Pharmaceutical composition of the present invention can various routinely pulverizing, water retting, and ethanol extraction, percolation filters, and processing technique such as concentrates and makes oral liquid, extractum coated tablet, capsule etc.
Particularly, concrete preparation technology's flow process of oral liquid of the present invention is as follows:
Each composition is pulverized the formation coarse powder, then
Extractum coated tablet of the present invention technological process is as follows:
Soft capsule preparation process chart of the present invention does not just add bulking agent with the flow process of extractum coated tablet, obtains fluid extract and does directly to go up the embedding of soft capsule Production and Packaging line.
Compositions of the present invention can be made into Unit Weight and makes agent for oral, and every of oral liquid contains 10ml.About every 0.3g of coated tablet and capsule, the adult obeys the each 10ml of oral liquid, each three of tablet and capsule three times (more than 12 years old) every day.
The present invention can fairly large input commercial production, and its each composition can amplify according to the above ratio and feeds intake.
Compositions of the present invention proves that through a large amount of clinical trials its centering students intelligence obstacle closes disease obvious curative effects is arranged, and is better than prior art.
The inventor has carried out clinical research and tracing study with the tablet of the present composition to 1072 routine dysnoesia syndrome patients, effective percentage reaches 90.96% and with oral liquid 300 example this disease patients is treated, effective percentage reaches 96%, and obvious effective rate reaches 65.7% and do not see any toxic and side effects.Illustrate that compositions of the present invention is the ideal medicament of this non-organic disease of treatment.
Hand-deliver is described in further detail content of the present invention with the form of embodiment under the present invention, but must not be with this as restriction to content of the present invention, allly include in the claim that awaits the reply of the present invention in the change of making on the various embodiments of the present invention basis.
Embodiment 1
Get Radix Ginseng 5g, Radix Astragali 15g, Arillus Longan 10g, Poria 10g, Radix Paeoniae Alba 12g, Radix Polygalae 110g, Radix Puerariae 10g, Cortex Phellodendri 6g, Rhizoma Acori Graminei 10g rises extend protection 4g, Radix Glycyrrhizae 5g, Fructus Viticis 10g with its pulverize separately, was soaked in water 2.5 hours, and institute's water exceeds all powder can be flooded.Decoct then three times, add for the first time the decocting in water 1.5 hours of 8 times of weight, add 6 times of decocting in water 1 hour for the second time, add 5 times of heavy water for the third time and boiled 1 hour, remove by filter medicinal residues then, filtrate decompression is concentrated (pressure-300---500mmhg makes weight reduce one times.The cooling back adds 65% ethanol equal weight, leaves standstill 48 hours, adds 2 times of weights of water then, make 3 precipitations to occur, and solids removed by filtration impurity, (300--500mmHg) be condensed into thick paste, thin up is to concentrating amount in one's power for the first time with filtrate decompression.The active carbon that adds 0.3% weight boiled 15 minutes, and cold preservation 24 hours is filtered, it is an amount of to add flavoring agent (Mel) in the filtrate, add distilled water, exceed (about 1: 1) with the suitable processing of its dilution factor, regulating ph with dilute aqueous solution of sodium bicarbonate is 7.5-7.8, refilter, go in the peace bottle sterilization treatment, packing with the amount embedding of every 10ml, get the oral liquid finished product, yield 95%.
Embodiment 2
With Radix Ginseng 10g, Arillus Longan 18g does solvent impregnated 24 hours by Chang Yuanjian fluid extract percolation (the 17th page of first appendix of Pharmacopoeia of the People's Republic of China nineteen ninety version) with 60% ethanol, makes percolation.Receive the about 210ml of percolation, be condensed into paste (relative density 1.18-1.22,80c, standby.
With Radix Polygalae 12g, Radix Paeoniae Alba 15g, Poria 12g, Radix Puerariae 12g, Cortex Phellodendri 8g, Radix Glycyrrhizae 6g, Radix Astragali 30g adds the suitable quantity of water steaming and decocting three times: 1.5 hours for the first time, be 1 hour the second, three time, then three times medicinal liquid is merged, filtering and concentrating is standby to half weight.
With Rhizoma Acori Graminei 18g, Fructus Viticis 16g, Rhizoma Cimicifugae 5g wipes medicinal residues with its volatile oil of 60% ethanol extraction.
Then the outrunner is joined paste, the concentrated solution that flavor medicines such as Radix Polygalae are made and state volatile oil and be mixed and made into fluid extract with the filler (as the carbon fatty acid magnesium) of active ingredient equivalent is granulated tabletting (every 0.25g by the rule method, polishing packing, sterilization the extractum coated tablet.
Embodiment 3
With Radix Ginseng 9g, Arillus Longan 16g, Radix Astragali 25g, Poria 14g, Radix Puerariae 13g, Cortex Phellodendri 10g, Radix Glycyrrhizae 8g, Radix Polygalae 14g, Radix Paeoniae Alba 17g, Rhizoma Acori Graminei 16g, Fructus Viticis 20g, Rhizoma Cimicifugae 6g, method by embodiment 2 is made fluid extract, but do not add filler, directly go up the soft capsule baling line, obtain soft capsule preparation of the present invention by normal rule method embedding (0.5g, grain) far away.
Embodiment 4
60 ages are divided into two groups, first group of 40 people (for product of the present invention is controlled group), second group of 20 people (being matched group) at random the middle school student of 11-17 between year.These 60 teenagers all have dysnoesia in various degree.Its symptom: shortness of breath and palpitation, dizzy forgetful, insomnia and dreamful sleep, headache, lack of appetite is indigestion and loss of appetite, body is strong weak, sends essence (female irregular menstruation), everyone all have in above eight symptoms more than four, its domestic animal: feel down in spirits, extremely worried, to feel oneself inferior and deceive oneself, attention laxes, detest teacher or father and mother, play truant or leave, sexual behaviour is arranged, the idea of committing suicide, everyone all has the performance more than five in above eight symptoms, and the diligent Wechsler intelligence scale for children of Wei Kesi (wip-cr) test iq value (90) the tongue pulse condition of revising through China: all show as pale tongue, tongue is white, thready and weak pulse without strength.But above teenager does not all have merging conscience, serious primary disease such as kidney and hemopoietic system, and anencephaly matter sexually transmitted disease (STD) becomes and psychosis.
Give oral liquid of the present invention each one (10ml) to first group, every day three times, oral 10 days is a course of treatment, obeys three courses of treatment altogether.
Give piracetam 0.8g/ time to second group (matched group), oral 10 days is a course of treatment.
Inactive other all medicines during the treatment.
The clinical development standard is as follows:
1 tcm syndrome curative effect, psychological indication curative effect adopt comprehensive score to judge, to be designated as (+) as symptom be 1 minute in score according to mild symptoms weight classification table; Slightly being designated as (++) is 2 minutes, severe (+++) be 3 minutes.Mark before its therapeutic index n=treatment back mark/treatment.Recovery from illness n=0, effective invalid n=0.5 in 0.2 5 (n＜0.50)
2 survey IQ
3 total effectses: recovery from illness: traditional Chinese medical science sign and psychological indication all disappear, and the tongue pulse condition is normal, and IQ is brought up to more than 100.Produce effects: traditional Chinese medical science sign, psychological indication is clearly better, (total mark reduces more than 75%), IQ improves more than 10 than before.Effectively: traditional Chinese medical science sign, psychological indication are improved (total mark reduces more than 50%) than before, and IQ improves more than 5.Invalid: as not reach above-mentioned effective standard.
：： ％ ％ ％ ％：40 4 ( 10.00 ) 19 ( 17.50 ) 14 ( 35.00 ) 3 ( 7.50 ) ：20 0 ( 0.00 ) 6 ( 0.00 ) 9 ( 45.00 ) 5 ( 25.00 ) ： ％ ％ ％ ％：40 3 ( 7.50 ) 25 ( 62.50 ) 10 ( 25.00 ) 2 ( 5.00 ) ：20 1 ( 5.00 ) 8 ( 40.00 ) 5 ( 25.00 ) 6 ( 30.00 ) ： ％ ％ ％ ％：40 2 ( 5.00 ) 22 ( 55.00 ) 12 ( 30.00 ) 4 ( 10.00 ) ：20 1 ( 5.00 ) 9 ( 45.00 ) 7 ( 35.00 ) 3 ( 15.00 )
75.63 ± 10.93 after the treatment brought up in average 45.37 ± 9.27 before by the treatment of its IQ treatment group, and matched group bring up to 74.00 ± 11.272 by 64.875 ± 5.56.
Other treat front and back thing significant change as blood pressure, heart rate, three big routines, liver function etc.Untoward reaction takes place in none example.
Claims (6)
1 one kinds of pure natural medical composition of medicine for the treatment of middle school student's dysnoesia syndrome, this medicine is composed as follows:
Radix Ginseng 5-10g Radix Astragali 15-30g Arillus Longan 10-18g
Poria 10-15g Radix Paeoniae Alba 12-18g Radix Polygalae 10-15g
Radix Puerariae 10-15g Cortex Phellodendri 6-10g Rhizoma Acori Graminei 10-18g
Rise extend protection 4-6g Radix Glycyrrhizae 5-10g Fructus Viticis 10-24g
Can amplify by above proportioning and feed intake and produce finished product in batches.
2 pharmaceutical compositions according to claim 1 wherein contain Radix Ginseng 7-10g, Radix Astragali 20-30g, and Arillus Longan 15-18g, Rhizoma Acori Graminei 15-18g, all the other content of respectively distinguishing the flavor of are constant.
3 compositionss according to right 1 and 2, it is a liquid oral liquid.
4 compositionss according to right 1 and 2, it is the extractum coated tablet.
5 compositionss according to right 1 and 2, it is the soft capsule ball.
A kind of method for the treatment of the pure natural medical combination of middle school student's dysnoesia syndrome of 6 preparations, comprise each component is pulverized by traditional diamond-making technique, water retting, the steaming and decocting percolation, technologies such as ethanol extraction filters, and is concentrated, be made into oral liquid and be poured in the peace bottle, be made into fluid extract and be pressed into coated tablet or make the fluid extract soft capsule of packing into and make the soft capsule pill.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95106738 CN1114584A (en) | 1995-06-21 | 1995-06-21 | Medicine for tonifying brain and raising intelligence |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 95106738 CN1114584A (en) | 1995-06-21 | 1995-06-21 | Medicine for tonifying brain and raising intelligence |
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| CN1114584A true CN1114584A (en) | 1996-01-10 |
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| CN 95106738 Pending CN1114584A (en) | 1995-06-21 | 1995-06-21 | Medicine for tonifying brain and raising intelligence |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103041264A (en) * | 2012-12-31 | 2013-04-17 | 青岛华仁信息技术开发有限公司 | Kudzuvine root brain-boosting and intelligence-boosting oral solution with function of preventing vascular dementia and preparation method thereof |
| CN103520622A (en) * | 2013-10-26 | 2014-01-22 | 王祖阳 | Traditional Chinese medicine prescription good for improving memory |
-
1995
- 1995-06-21 CN CN 95106738 patent/CN1114584A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103041264A (en) * | 2012-12-31 | 2013-04-17 | 青岛华仁信息技术开发有限公司 | Kudzuvine root brain-boosting and intelligence-boosting oral solution with function of preventing vascular dementia and preparation method thereof |
| CN103041264B (en) * | 2012-12-31 | 2014-11-05 | 青岛华仁技术孵化器有限公司 | Kudzuvine root brain-boosting and intelligence-boosting oral solution with function of preventing vascular dementia and preparation method thereof |
| CN103520622A (en) * | 2013-10-26 | 2014-01-22 | 王祖阳 | Traditional Chinese medicine prescription good for improving memory |
| CN103520622B (en) * | 2013-10-26 | 2016-03-16 | 崔子扬 | Contribute to the Chinese prescription improving memory |
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