CN111450193A - Miao medicine composition for treating gout and preparation method thereof - Google Patents

Miao medicine composition for treating gout and preparation method thereof Download PDF

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CN111450193A
CN111450193A CN202010325688.6A CN202010325688A CN111450193A CN 111450193 A CN111450193 A CN 111450193A CN 202010325688 A CN202010325688 A CN 202010325688A CN 111450193 A CN111450193 A CN 111450193A
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wine
parts
medicine composition
miao medicine
treating gout
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唐荣成
石昌超
石昌俊
石昌杰
唐海华
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    • A61K2236/30—Extraction of the material
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Abstract

The invention relates to a Miao medicine composition for treating gout and a preparation method thereof, wherein the Miao medicine composition for treating gout is prepared by taking Chinese angelica, ligusticum wallichii, radix rehmanniae, cinnamon, eucommia ulmoides, myrrh, edible tulip, polygonum cuspidatum and menthol as raw materials and carrying out proper weight proportion, and finally the Miao medicine composition for rapidly relieving pain and effectively treating gout is prepared. The components of the product disclosed by the invention have synergistic effects, can quickly play the roles of clearing heat and promoting diuresis, cooling blood and dredging collaterals, and dissipating blood stasis and relieving pain, has a remarkable curative effect on gout treatment, is safe, does not have side effects, and is simple and convenient to use. The invention provides a novel medicinal liquor for treating gout, which accords with Miao medicine theory, has good taste, coordinated aroma, good stability, clearness and transparency, has no sediment or suspended matters, and can quickly take effect on gout; further provides a reasonable preparation method, and the preparation method is simple and easy to implement, mild in condition, good in stability and easy to popularize.

Description

Miao medicine composition for treating gout and preparation method thereof
Technical Field
The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a Miao medicine composition for treating gout and a preparation method thereof.
Background
Gout is a common and complex type of arthritis, which can be suffered by all ages, with higher incidence in men than women. Patients with gout often have sudden joint pain at night, the joint is in urgent attack, severe pain, edema, red swelling and inflammation appear at the joint, and the pain is slowly relieved until the pain disappears for days or weeks. The affected joints are red, swollen and inflamed finally, tissues become soft after edema, activities are limited, and daily life is affected finally. If the treatment is not carried out in time, the pain feeling is more and more intense as a result of the delay, which is difficult to endure for people.
Miao medicine refers to Chinese herbal medicines planted and grown in Miao mountain, Wumeng mountain, Wuling mountain, Shanxi mountain, Damian mountain and Hainan mountain of Miao ethnic group, and also refers to Miao ethnic group medicinal culture. The Miao medicine has deeper understanding on pathogenic factors, disease diagnosis, treatment, prevention and the like, has a plurality of unique points in the aspect of clinical prescription medication, accumulates abundant medical experience, has unique advantages on gout treatment methods, has various traditional herbal medicines for treating gout on the market, and needs to develop medicines for treating gout with better curative effect.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a Miao medicine composition for treating gout and a preparation method thereof. The components of the product disclosed by the invention have synergistic effects, can quickly play roles in clearing heat and promoting diuresis, cooling blood and dredging collaterals, and dissipating blood stasis and relieving pain, has a remarkable curative effect on gout, is safe and free of side effects, and is simple and convenient to use.
The technical scheme adopted by the invention is as follows:
a Miao medicine composition for treating gout comprises the following raw material components:
6-10 parts of angelica, 4-6 parts of ligusticum wallichii, 6-15 parts of radix rehmanniae, 4-6 parts of cinnamon, 6-15 parts of eucommia ulmoides, 3-5 parts of myrrh, 3-5 parts of edible tulip, 2-4 parts of polygonum cuspidatum and 1-3 parts of menthol.
Further preferably, the Miao medicine composition for treating gout comprises the following raw material components:
8 parts of angelica, 5 parts of ligusticum wallichii, 10.5 parts of radix rehmanniae, 5 parts of cinnamon, 10.5 parts of eucommia ulmoides, 4 parts of myrrh, 4 parts of Indian iphigenia bulb, 3 parts of polygonum cuspidatum and 2 parts of menthol.
The dosage form of the Miao medicine composition is any one of powder, wine or paste.
A method for preparing the Miao medicine wine for treating gout comprises the following steps:
(1) mixing the raw materials except Mentholum, extracting with wine under sealed condition, and filtering to obtain extractive solution and residue;
(2) squeezing the filter residue, mixing the squeezed liquid with the leaching liquor, and filtering to obtain wine base;
(3) dissolving Mentholum in wine, adding into the wine base, and stirring to obtain Mentholum wine base;
(4) adjusting the alcohol degree of the menthol base wine by using wine and purified water to obtain adjusted wine; and then standing, filtering and encapsulating the adjusted wine to obtain the wine.
Further, the wine is any one of kaoliang wine, corn wine, glutinous rice wine or pea wine.
Further, the wine is kaoliang spirit.
Further, the alcohol content of the wine is 60-65% vol.
Further, in the step (1), the mass ratio of the raw materials to the wine is 1 (6-10); the leaching time is 8-12 days.
Further, in the step (2), a stainless steel filter screen of 100-150 meshes is used for the filtration.
Further, in the step (3), the mass ratio of the menthol to the wine is 1 (6-10); the stirring speed is 25-60r/min, and the stirring time is 20-30 min.
Further, in the step (4), the alcohol precision of the adjusted wine is 53-55% vol; the standing time is 10-14 h; the filtration uses a plate-and-frame filter with the aperture of the filter membrane of 0.1-1 um.
The application method comprises oral administration and external application: the oral administration is twice a day with 5ml for the first week and 10ml for the second and later weeks, and four weeks is a treatment course; the external application comprises applying appropriate amount of medicated liquor on affected part, kneading and massaging, and applying for 3 times per day; the oral administration and the external application are simultaneously used for treatment.
The action of the raw materials of the present invention will be briefly described below.
Dang Gui is warm in nature, sweet and pungent in flavor. It enters liver meridian, heart meridian and spleen meridian. Tonify blood, activate blood, regulate menstruation, alleviate pain, moisten intestines and relieve constipation. It is used to treat sallow complexion due to blood deficiency, vertigo, palpitation, menoxenia, amenorrhea, dysmenorrhea, abdominal pain due to deficiency cold, constipation due to intestinal dryness, rheumatic arthralgia, traumatic injury, carbuncle, cellulitis, and pyocutaneous disease.
Chuan Xiong is warm in nature and pungent in flavor. It enters liver meridian, gallbladder meridian and pericardium meridian. Promote blood circulation and move qi, dispel wind and alleviate pain. Can be used for treating thoracic obstruction, cardialgia, pricking pain in chest and hypochondrium, traumatic injury, menoxenia, amenorrhea, dysmenorrhea, addictions, abdominal pain, headache, and rheumatalgia.
Sheng Di Huang is cold in nature and sweet in taste. They enter heart, liver and kidney meridians. Clearing heat and cooling blood, nourishing yin and promoting fluid production. It is commonly indicated for deep-red tongue with polydipsia, yin deficiency with internal heat, bone steaming with internal heat, internal heat with diabetes, hematemesis, epistaxis, macula and eruption
Rou Gui is pungent and sweet in flavor, with large heat in property. It enters kidney, spleen, heart and liver meridians. Tonify fire and strengthen yang, induce fire to return to original, dispel cold to alleviate pain, and warm and dredge meridians. Can be used for treating sexual impotence, cold womb, cold pain of waist and knee, asthma due to kidney deficiency, floating of deficient yang, giddiness, conjunctival congestion, cold pain of heart and abdomen, vomiting and diarrhea due to deficiency cold, cold hernia, abdominal pain, dysmenorrhea, and amenorrhea.
Du Zhong is warm in nature and sweet in flavor. It enters liver and kidney meridians. Tonify liver and kidney, strengthen tendons and bones, and prevent miscarriage. It is indicated for lumbago due to kidney deficiency, weakness of tendons and bones, bleeding during pregnancy, fetal irritability, and hypertension.
Mo Yao, neutral in nature, pungent and bitter in flavor. They enter heart, liver and spleen meridians. Removing blood stasis, relieving pain, eliminating swelling, and promoting granulation. Can be used for treating thoracic obstruction, cardialgia, gastralgia, dysmenorrhea, amenorrhea, puerperal stagnation, abdominal mass, rheumatic arthralgia, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Pseudobulbus Cremastrae seu pleiones, sweet in flavor, slightly pungent and cold in nature; it enters liver, stomach and lung meridians. The efficacy is mainly as follows: clearing away heat and toxic material, relieving swelling and dissipating stagnation. Can be used for treating carbuncle, cellulitis, malignant sore, scrofula, tuberculosis, pharyngalgia, pharyngitis, snake bite, and insect bite.
Giant knotweed rhizome, bitter in taste and cold in nature; it enters liver, gallbladder and lung meridians. The efficacy is mainly as follows: promoting blood circulation, relieving pain, clearing away heat and toxic materials, promoting diuresis, eliminating phlegm, and relieving cough. Can be used for treating amenorrhea due to blood stagnation, rheumatalgia, traumatic injury, jaundice due to damp-heat pathogen, leukorrhagia due to turbid discharge, scald, skin ulcer, carbuncle, toxic swelling, and cough due to lung heat.
The menthol has the function of mainly stimulating skin mucosa, and has cool feeling on the local part while relieving itching, diminishing inflammation and relieving pain. It can be used for treating pain, inflammation and swelling, and also for treating headache, rhinitis, pharyngitis and laryngitis by oral administration.
The invention has the beneficial effects that:
the Miao medicine composition for treating gout is prepared by taking Chinese angelica, ligusticum wallichii, radix rehmanniae, cinnamon, eucommia ulmoides, myrrh, edible tulip, polygonum cuspidatum and menthol as raw materials and carrying out proper weight proportion, and finally the Miao medicine composition for rapidly relieving pain and effectively treating gout is prepared. The rehmannia root, the Indian iphigenia bulb and the giant knotweed rhizome in the product have the effects of clearing heat, cooling blood and promoting diuresis, the Chinese angelica and the szechuan lovage rhizome have the effects of warming and activating meridians and collaterals, promoting blood circulation and activating qi, the myrrh and the cinnamon have the effects of dissipating blood stasis and relieving pain, and the eucommia bark and the mint ice have the effects of strengthening muscles and bones, diminishing inflammation and the like in combination, so that the components have synergistic effect, the traditional Chinese medicine has a remarkable curative effect on treating gout, is safe, does not have side effects, and is simple. More than 2000 patients are treated in 2019 years by using the product, wherein 90% of patients are basically cured, and the curative effect is remarkable. The invention provides a novel medicinal liquor for treating gout, which accords with Miao medicine theory, has good taste, coordinated aroma, good stability, clearness and transparency, has no sediment or suspended matters, and can quickly take effect on gout; and further provides a reasonable preparation method, and the preparation method is simple and easy to implement, mild in condition, good in stability and easy to popularize.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
In the following examples, 1 part by weight represents 1 g.
Example 1
The embodiment provides a Miao medicine composition for treating gout, which comprises the following raw material components:
6 parts of angelica sinensis, 4 parts of ligusticum wallichii, 6 parts of radix rehmanniae, 4 parts of cinnamon, 6 parts of eucommia ulmoides, 3 parts of myrrh, 3 parts of Indian iphigenia bulb, 2 parts of polygonum cuspidatum and 1 part of menthol.
Example 2
The embodiment provides a Miao medicine wine for treating gout, which comprises the following raw material components:
6 parts of angelica sinensis, 4 parts of ligusticum wallichii, 6 parts of radix rehmanniae, 4 parts of cinnamon, 6 parts of eucommia ulmoides, 3 parts of myrrh, 3 parts of Indian iphigenia bulb, 2 parts of polygonum cuspidatum and 1 part of menthol.
Further, the present embodiment provides a preparation method of the Miao medicine wine for treating gout, which includes the following steps:
(1) mixing the other raw materials except the mentholum, carrying out closed leaching on the raw materials for 8 days by using corn wine with the mass being 6 times of that of the raw materials and the alcohol degree being 65% vol, and filtering to obtain leaching liquor and filter residues;
(2) squeezing the filter residue, mixing squeezed liquid and the leaching liquor, and filtering with a 100-mesh stainless steel filter screen to obtain wine base;
(3) dissolving the mentholum by using corn wine with the mass 6 times of that of the raw material and the alcohol content of 65% vol, adding the dissolved mentholum into the wine base, and stirring for 30min at the speed of 25r/min to obtain the mentholum wine base;
(4) adjusting the alcohol content of the menthol base wine to 53% vol by using corn wine with the alcohol content of 65% vol and purified water to obtain adjusted wine; and standing the adjusted wine for 10 hours, filtering by using a plate-and-frame filter with the filter membrane aperture of 0.1um, and encapsulating to obtain the Miao medicine wine.
Example 3
The embodiment provides a Miao medicine wine for treating gout, which comprises the following raw material components:
10 parts of angelica sinensis, 6 parts of ligusticum wallichii, 15 parts of radix rehmanniae, 6 parts of cinnamon, 15 parts of eucommia ulmoides, 5 parts of myrrh, 5 parts of Indian iphigenia bulb, 4 parts of polygonum cuspidatum and 3 parts of menthol.
Further, the present embodiment provides a preparation method of the Miao medicine wine for treating gout, which includes the following steps:
(1) mixing the other raw materials except the menthol, carrying out closed leaching on the raw materials for 12 days by using glutinous rice wine with the mass being 10 times that of the raw materials and the alcohol degree being 60% vol, and filtering to obtain leaching liquor and filter residues;
(2) squeezing the filter residue, mixing squeezed liquid and the leaching liquor, and filtering with a 150-mesh stainless steel filter screen to obtain raw wine;
(3) dissolving mentholum in glutinous rice wine with the alcohol content of 60% vol and the mass of 10 times of the raw materials, adding the dissolved mentholum into the wine base, and stirring for 20min at the speed of 60r/min to obtain the mentholum wine base;
(4) adjusting the alcohol degree of the menthol base wine to 55% vol by using glutinous rice wine with the alcohol degree of 60% vol and purified water to obtain adjusted wine; and standing the adjusted wine for 14h, filtering by using a plate-and-frame filter with the filter membrane aperture of 1um, and encapsulating to obtain the Miao medicine wine.
Example 4
The embodiment provides a Miao medicine wine for treating gout, which comprises the following raw material components:
8 parts of angelica, 5 parts of ligusticum wallichii, 10.5 parts of radix rehmanniae, 5 parts of cinnamon, 10.5 parts of eucommia ulmoides, 4 parts of myrrh, 4 parts of Indian iphigenia bulb, 3 parts of polygonum cuspidatum and 2 parts of menthol.
Further, the present embodiment provides a preparation method of the Miao medicine wine for treating gout, which includes the following steps:
(1) mixing the other raw materials except the menthol, carrying out closed leaching on the raw materials for 10 days by using kaoliang spirit with the mass of 8 times of the raw materials and the alcohol degree of 63% vol, and filtering to obtain leaching liquor and filter residues;
(2) squeezing the filter residue, mixing squeezed liquid and the leaching liquor, and filtering with a 130-mesh stainless steel filter screen to obtain raw wine;
(3) dissolving mint ice by using sorghum liquor with the mass being 8 times of that of the raw material and the alcohol content being 63% vol, adding the dissolved mint ice into the raw wine, and stirring for 25min at the speed of 43r/min to obtain mint ice raw wine;
(4) adjusting the alcohol content of the menthol base wine to 54% vol by using kaoliang spirit and purified water with the alcohol content of 63% vol to obtain adjusted wine; and standing the adjusted wine for 12h, filtering by using a plate-and-frame filter with the filter membrane aperture of 0.5um, and encapsulating to obtain the Miao medicine wine.
Example 5
This example differs from example 4 only in that the wine used was pea wine, and the other operations were the same as example 4.
Typical case
1. The wine is applied to an affected part three times a day and is taken orally at the same time, 5ml is taken every time, the wine is taken in the morning and at the evening every day, the red swelling and pain are obviously relieved after three days of treatment, and the symptom disappears and is cured after the wine is continuously used for one week.
2. The medicinal liquor is applied to an affected part three times a day and is taken orally at the same time, 5ml of the medicinal liquor is taken every time, and the medicinal liquor is taken on an empty stomach in the morning and at night every day, so that symptoms are obviously relieved after the medicinal liquor is taken for one week, and the patients are cured after the medicinal liquor is taken for 5 treatment courses.
3. The liquor is applied to an affected part three times a day, and is taken orally at the same time, 5ml each time, and the liquor is taken on an empty stomach in the morning and at night every day, and the patient can be cured after taking the medicine for 6 courses.
4. Ran for a certain time, men and Chongqing Yuanyang county are diagnosed in 2019 in 24 days 3 and month, gout and kidney stone are diagnosed, symptoms are improved after the medicine is taken for one treatment course, and the patients are cured after the medicine is continuously taken for 3 treatment courses.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (10)

1. The Miao medicine composition for treating gout is characterized by comprising the following raw material components:
6-10 parts of angelica, 4-6 parts of ligusticum wallichii, 6-15 parts of radix rehmanniae, 4-6 parts of cinnamon, 6-15 parts of eucommia ulmoides, 3-5 parts of myrrh, 3-5 parts of edible tulip, 2-4 parts of polygonum cuspidatum and 1-3 parts of menthol.
2. The Miao medicine composition for treating gout according to claim 1, wherein the raw material components comprise:
8 parts of angelica, 5 parts of ligusticum wallichii, 10.5 parts of radix rehmanniae, 5 parts of cinnamon, 10.5 parts of eucommia ulmoides, 4 parts of myrrh, 4 parts of Indian iphigenia bulb, 3 parts of polygonum cuspidatum and 2 parts of menthol.
3. The Miao medicine composition for treating gout according to any one of claims 1 to 2, wherein the dosage form of the Miao medicine composition is any one of powder, wine and paste.
4. The method for preparing a miao medicine composition for treating gout of claim 3, wherein the preparation of the medicated wine comprises the following steps:
(1) mixing the raw materials except Mentholum, extracting with wine under sealed condition, and filtering to obtain extractive solution and residue;
(2) squeezing the filter residue, mixing the squeezed liquid with the leaching liquor, and filtering to obtain wine base;
(3) dissolving Mentholum in wine, adding into the wine base, and stirring to obtain Mentholum wine base;
(4) adjusting the alcohol degree of the menthol base wine by using wine and purified water to obtain adjusted wine; and then standing, filtering and encapsulating the adjusted wine to obtain the wine.
5. The method for preparing a Miao medicine composition for treating gout as set forth in claim 4, wherein the wine is any one of kaoliang wine, corn wine, glutinous rice wine or pea wine.
6. The method for preparing a Miao medicine composition for the treatment of gout as claimed in claim 5, wherein the alcohol content of the wine is 60-65% vol.
7. The preparation method of the Miao medicine composition for treating gout according to claim 4, wherein in the step (1), the mass ratio of the raw materials to the wine is 1 (6-10); the leaching time is 8-12 days.
8. The method for preparing the Miao medicine composition for treating gout as claimed in claim 4, wherein in the step (2), the filter is a stainless steel filter screen of 100-150 meshes.
9. The preparation method of the Miao medicine composition for treating gout according to claim 4, wherein in the step (3), the mass ratio of the menthol to the wine is 1 (6-10); the stirring speed is 25-60r/min, and the stirring time is 20-30 min.
10. The method for preparing the Miao medicine composition for treating gout according to claim 4, wherein in the step (4), the alcohol content of the adjusted wine is 53 to 55% vol; the standing time is 10-14 h; the filtration uses a plate-and-frame filter with the aperture of the filter membrane of 0.1-1 um.
CN202010325688.6A 2020-04-23 2020-04-23 Miao medicine composition for treating gout and preparation method thereof Pending CN111450193A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109321418A (en) * 2018-12-12 2019-02-12 张朔生 A kind of sealwort health wine and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109321418A (en) * 2018-12-12 2019-02-12 张朔生 A kind of sealwort health wine and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
代榭: "《痛风病的治疗与调养》", 31 July 2018, 上海科学技术文献出版社 *
李溪: "辨证分型治疗痛风性关节炎临床观察", 《实用中医内科杂志》 *

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