CN111426852A - Urine detection device and urinal - Google Patents

Urine detection device and urinal Download PDF

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Publication number
CN111426852A
CN111426852A CN202010330012.6A CN202010330012A CN111426852A CN 111426852 A CN111426852 A CN 111426852A CN 202010330012 A CN202010330012 A CN 202010330012A CN 111426852 A CN111426852 A CN 111426852A
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China
Prior art keywords
sample
module
urine
microscopic examination
communicated
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Withdrawn
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CN202010330012.6A
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Chinese (zh)
Inventor
李春林
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Chongqing Defang Information Technology Co ltd
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Chongqing Defang Information Technology Co ltd
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Priority to CN202010330012.6A priority Critical patent/CN111426852A/en
Publication of CN111426852A publication Critical patent/CN111426852A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N15/1436Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004Cleaning sample transfer devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486Counting the particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • G01N2035/00158Elements containing microarrays, i.e. "biochip"

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides a urine detection device, which comprises a microscopic examination module, wherein the microscopic examination module comprises a microscopic examination electromagnetic valve, a pressure sensor, a counting cell, a cut-off electromagnetic valve and an image acquisition module; the inlet end of the counting cell is communicated with the outlet end of the microscopic examination electromagnetic valve; the outlet end of the counting chamber is communicated with the inlet end of a cut-off solenoid valve, and the cut-off solenoid valve is communicated with the urinal; the image acquisition module is used for acquiring images of samples in the counting cell. The urine detection device can be arranged on the urinal, can finish sampling of urine, and can perform microscopic examination on the urine. The device can take a sample automatically, need not artifical sample and the artifical transmission sample of connecing, has higher convenience. Particularly, after the counting cell is completely filled with the sample, the sample is stopped being conveyed to the counting cell, the microscopic examination electromagnetic valve and the cutoff electromagnetic valve are closed, the sample in the counting cell is in a static state at the moment, and a detection result with higher accuracy can be obtained by collecting a sample image in the static state.

Description

Urine detection device and urinal
Technical Field
The invention relates to the technical field of urine detection, in particular to a urine detection device and a urinal.
Background
Urine is a daily necessary procedure for all people, the urine condition can directly reflect the health conditions of various bodies, the urine can reflect whether diseases such as kidney diseases, lower urinary tract diseases, extrarenal diseases, liver and gall diseases, diabetes and the like exist, and urine detection has a great effect on early detection of the diseases and health condition assessment, and comprises routine urine analysis, detection of visible components in urine (such as urine red blood cells, white blood cells and the like) and the like.
The rapid screening analysis of urine by using a multi-linked biochip, namely urine routine, is a simple, convenient and rapid urine screening method, although the method is rapid and simple, only qualitative and semi-quantitative effects can be exerted due to the methodological limitation, the detection result has false positive and false negative, and the result is influenced by a plurality of factors.
Microscopic examination (referred to as microscopic examination for short) using urine is an important content of urine examination. Urine microscopy can detect cast, cell, crystal, bacteria, and other visible amorphous and amorphous components of microorganisms, parasites, and bacteria in urine.
Generally, a series of processes of registering to a hospital, visiting a clinic, paying a fee, queuing by a clinical laboratory, waiting for a detection report and revising a doctor are required for urine examination, and a great deal of time and energy are required for routine urine examination.
Disclosure of Invention
The first purpose of the invention is to provide a urine detection device, which can solve the problem that the conventional detection of urine needs long time;
a second object of the present invention is to provide a urinal using the urine detection device as described above.
A urine detection device comprises a microscopic examination module, wherein the microscopic examination module comprises a microscopic examination electromagnetic valve, a pressure sensor, a counting cell, a cutoff electromagnetic valve and an image acquisition module;
the inlet end of the counting cell is communicated with the outlet end of the microscopic examination electromagnetic valve;
the outlet end of the counting chamber is communicated with the inlet end of a cut-off solenoid valve, and the cut-off solenoid valve is communicated with the urinal;
the image acquisition module is used for acquiring images of samples in the counting cell.
Preferably, the microscopic examination module further comprises a pressure sensor, and the pressure sensor is arranged on a connecting pipeline between the counting cell and the microscopic examination electromagnetic valve.
Preferably, the image acquisition module comprises a microscope, a microscope light source and a camera;
the microscope and the microscope light source are oppositely arranged, and the counting cell is arranged between the microscope and the microscope light source;
the camera is arranged at the image acquisition interface of the microscope.
Preferably, the microscope comprises an objective lens, a lens barrel and an image acquisition interface;
the microscope light source is arranged on the base bracket right below the objective lens, and the counting cell is fixed between the microscope light source and the objective lens;
the objective lens and the image acquisition interface are connected to the lens cone, and the lens cone is fixed on the base support.
Preferably, the urine detection device comprises a urine sampling module, a sample pipeline switching module and a sample adding module;
the urine collection module is communicated with the sample adding module and the microscopic examination module through the sample pipeline switching module, and the sample pipeline switching module selectively guides the sample collected by the urine collection module to the sample adding module and/or the microscopic examination module.
Preferably, the urine collection module comprises a straight flow pump;
the inlet end of the direct current pump is connected with the sample collecting end through a pipeline, and the outlet end of the direct current pump is communicated with the sample pipeline switching module.
Preferably, the sample pipeline switching module comprises a sample buffer pool, a sample adding pump and an overflow pipe;
the inlet end of the sample buffer pool is communicated with the outlet end of the urine collection module, the outlet end of the sample buffer pool is communicated with the inlet end of the sample adding pump, and an overflow port on the sample buffer pool is communicated with an overflow pipe;
the pipeline connected with the outlet end of the sample adding pump is divided into two paths, the first path is communicated with the sample adding electromagnetic valve of the sample adding module, and the second path is communicated with the inlet end of the microscopic examination electromagnetic valve.
A urinal comprising a urine detection device as described above.
Has the advantages that:
in the present embodiment, the urine detection device can be installed on a urinal, and can complete sampling of urine and perform microscopic examination of urine.
The device can take a sample automatically, need not artifical sample and the artifical transmission sample of connecing, has higher convenience.
Particularly, after the counting cell is completely filled with the sample, the sample is stopped being conveyed to the counting cell, the microscopic examination electromagnetic valve and the cutoff electromagnetic valve are closed, the sample in the counting cell is in a static state at the moment, and a detection result with higher accuracy can be obtained by collecting a sample image in the static state.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a process flow diagram of a urine testing device according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a microscopy module according to an embodiment of the present invention.
Description of reference numerals:
100: a urine collection module; 200: a sample pipeline switching module; 300: a sample adding module; 400: a microscopic examination module;
401: a counting pool; 402: a microscope light source; 403: an image acquisition module; 404: an objective lens; 405: a lens barrel; 406: an image acquisition interface; 407: a base support.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, features defined as "first", "second", may explicitly or implicitly include one or more of the described features. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise. Furthermore, the terms "mounted," "connected," and "connected" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
As shown in fig. 1 and 2, in the present embodiment, a urine detection device is provided, which includes a microscopy module 400, wherein the microscopy module 400 includes a microscopy solenoid valve, a counting cell 401, a truncation solenoid valve, and an image acquisition module 403.
The inlet end of the counting cell 401 is communicated with the outlet end of the microscopic examination electromagnetic valve. The outlet end of the counting chamber 401 is communicated with the inlet end of a cut-off solenoid valve, and the cut-off solenoid valve is communicated with the urinal. The term "the shut-off solenoid valve is in communication with the urinal" means that the sample discharged from the shut-off valve can flow into the urinal. The image acquisition module 403 is used for acquiring images of the samples in the counting cell 401.
In the present embodiment, the device can be installed in a urinal, and can complete sampling of urine and perform microscopic examination of the urine.
The device can take a sample automatically, need not artifical sample and the artifical transmission sample of connecing, has higher convenience.
Particularly, after the counting cell is completely filled with the sample, the sample is stopped being conveyed to the counting cell, the microscopic examination electromagnetic valve and the cutoff electromagnetic valve are closed, the sample in the counting cell is in a static state at the moment, and a detection result with higher accuracy can be obtained by collecting a sample image in the static state.
The microscopy module 400 further comprises a pressure sensor, and the pressure sensor is arranged on a connecting pipeline between the counting cell 401 and the microscopy solenoid valve.
After the microscopic examination solenoid valve and the cut-off valve are closed, whether the counting cell has a blockage condition can be judged through the detected pressure value of the pressure sensor, if the pressure value is normal, the condition that the counting cell is not blocked and accords with image acquisition is shown, if the pressure value of the pressure sensor exceeds the normal value, the condition that the counting cell pipeline is blocked and does not accord with image acquisition is shown, and detection is stopped.
The image acquisition module 403 includes a microscope, a microscope light source 402, and a camera. The microscope and the microscope light source 402 are arranged opposite to each other, and the counting cell 401 is arranged between the microscope and the microscope light source 402. The camera is disposed at the microscope image acquisition interface 406.
Specifically, the counting cell 401 is fixed between the microscope light source 402 and the microscope objective 404, so that the bottom surface of the channel inside the counting cell 401 is located at the focal plane of the microscope objective 404. The image acquisition module 403 is fixed on the microscope image acquisition interface 406, and the image acquisition module 403 is connected with the main control board through a data line.
The microscope comprises an objective 404, a lens barrel 405 and an image acquisition interface 406, wherein a microscope light source 402 is arranged on a base support 407 right below the objective 404, a counting cell 401 is fixed between the microscope light source 402 and the objective 404, the objective 404 and the image acquisition interface 406 are connected to the lens barrel 405, and the lens barrel 405 is fixed on the base support 407.
The urine detection device comprises a urine sampling module 100, a sample pipeline switching module 200 and a sample adding module 300. Urine collection module 100 switches module 200 through the sample pipeline and communicates with application of sample module 300, microscopic examination module 400, and sample pipeline switches module 200 and selectively leads the sample water conservancy diversion that urine collection module 100 gathered to application of sample module 300 and/or microscopic examination module 400.
Urine collection module 100 includes urine collection module includes the through-flow pump, and the entrance point of through-flow pump passes through the tube coupling sample collection end, and the exit end and the sample pipeline of through-flow pump switch the module intercommunication.
The collecting end is a filter head, the urine sample is collected through the filter head, and the collected sample is output to the sample pipeline switching module by the direct current pump. The straight-flow pump is specifically a straight-flow peristaltic pump.
The sample pipeline switching module 200 includes a sample buffer tank, a sample adding pump and an overflow pipe. The entrance point in sample buffer memory pond and urine collection module's exit end intercommunication, the exit end in sample buffer memory pond and the entry end intercommunication of application of sample pump, overflow mouth and overflow pipe intercommunication on the sample buffer memory pond.
The application of sample pump is wriggling application of sample pump, and the pipeline that application of sample pump outlet end is connected divide into two the tunnel, and first road communicates with the application of sample solenoid valve of application of sample module 300, and the second road communicates with the entry end of microscopic examination solenoid valve. The overflow pipe is communicated with the liquid outlet. Through the opening and closing of the sample adding electromagnetic valve and the microscopic examination electromagnetic valve, samples can be selectively conveyed to the sample adding module or the microscopic examination module.
The specific detection process of the urine detection device is as follows:
urine microscopic examination is started after the sample adding module finishes adding samples, at the moment, a main control board of the urine detection device sends a signal to a DC power supply control board, the DC power supply control board controls a microscopic examination electromagnetic valve and a cut-off valve to be electrified, a normally closed end of the microscopic examination electromagnetic valve is communicated with an input end of a pressure sensor, the cut-off valve is communicated, the main control board sends a signal to a motor driver, the motor driver controls a peristaltic sample adding pump to rotate forwards to enable a sample to flow through the microscopic examination electromagnetic valve, the pressure sensor, a counting cell 401, the cut-off valve and a liquid discharge pipeline to be finally discharged into a urinal water outlet, the main control board sends a signal to the DC power supply control board when the counting cell 401 is completely filled with the sample, the DC power supply control board controls a microscope light source 402 to be lightened, the peristaltic sample adding pump to be powered off, the microscopic examination electromagnetic valve to be powered off and the cut-off, the main control board sends a control signal to the image acquisition module 403, controls the image acquisition module 403 to take a picture and transmits the collected picture to the main control board through a data line, after taking the picture, the main control board sends a signal to the DC power control board and the motor driver, the DC power control board controls the power-on of the microscopic examination electromagnetic valve and the cut-off valve, the circulation pipeline of the microscopic examination sample is conducted, the motor driver controls the peristaltic sample adding pump to rotate forwards for a certain number of steps and then to be powered off, so that the sample in the counting cell 401 flows (namely, a new sample under the microscope is replaced), the main control board sends a signal to the DC power control board, the DC power control board controls the power-off of the microscopic examination electromagnetic valve and the power-off of the cut-off valve, at the moment, the front part and the back part of the sample in the counting cell 401 are cut off and in a static state, the main control board uploads the pictures to the server through WIFI or a mobile network; and executing the microscopic examination program, and circulating the photographing process until 20 times of photographing is completed.
If the pressure of the pressure sensor exceeds the normal value in the circulation process, the situation that the channel of the counting cell 401 is possibly blocked is indicated, and when the pressure is detected to be ultrahigh, the main control board sends a signal to the DC power supply control board to stop the detection process.
In the present embodiment, there is also provided a urinal using the urine detection device as described above.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims (8)

1. A urine detection device is characterized by comprising a microscopic examination module, wherein the microscopic examination module comprises a microscopic examination electromagnetic valve, a pressure sensor, a counting cell, a cut-off electromagnetic valve and an image acquisition module;
the inlet end of the counting cell is communicated with the outlet end of the microscopic examination electromagnetic valve;
the outlet end of the counting chamber is communicated with the inlet end of a cut-off solenoid valve, and the cut-off solenoid valve is communicated with the urinal;
the image acquisition module is used for acquiring images of samples in the counting cell.
2. The urine detection device of claim 1, wherein the microscopy module further comprises a pressure sensor disposed on a connection line between the counting cell and the microscopy solenoid valve.
3. The urine testing device of claim 1, wherein the image acquisition module comprises a microscope, a microscope light source and a camera;
the microscope and the microscope light source are oppositely arranged, and the counting cell is arranged between the microscope and the microscope light source;
the camera is arranged at the image acquisition interface of the microscope.
4. The urine testing device of claim 3, wherein the microscope comprises an objective lens, a lens barrel and an image acquisition interface;
the microscope light source is arranged on the base bracket right below the objective lens, and the counting cell is fixed between the microscope light source and the objective lens;
the objective lens and the image acquisition interface are connected to the lens cone, and the lens cone is fixed on the base support.
5. The urine testing device of claim 1, wherein the urine testing device comprises a urine sampling module, a sample pipeline switching module and a sample adding module;
the urine collection module is communicated with the sample adding module and the microscopic examination module through the sample pipeline switching module, and the sample pipeline switching module selectively guides the sample collected by the urine collection module to the sample adding module and/or the microscopic examination module.
6. The urine testing device of claim 5, wherein the urine collection module comprises a straight flow pump;
the inlet end of the direct current pump is connected with the sample collecting end through a pipeline, and the outlet end of the direct current pump is communicated with the sample pipeline switching module.
7. The urine detection device according to claim 5, wherein the sample pipeline switching module comprises a sample buffer pool, a sample adding pump and an overflow pipe;
the inlet end of the sample buffer pool is communicated with the outlet end of the urine collection module, the outlet end of the sample buffer pool is communicated with the inlet end of the sample adding pump, and an overflow port on the sample buffer pool is communicated with an overflow pipe;
the pipeline connected with the outlet end of the sample adding pump is divided into two paths, the first path is communicated with the sample adding electromagnetic valve of the sample adding module, and the second path is communicated with the inlet end of the microscopic examination electromagnetic valve.
8. A urinal comprising the urine detection device according to any one of claims 1 to 7.
CN202010330012.6A 2020-04-24 2020-04-24 Urine detection device and urinal Withdrawn CN111426852A (en)

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CN202010330012.6A CN111426852A (en) 2020-04-24 2020-04-24 Urine detection device and urinal

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Application Number Priority Date Filing Date Title
CN202010330012.6A CN111426852A (en) 2020-04-24 2020-04-24 Urine detection device and urinal

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112782420A (en) * 2020-12-30 2021-05-11 迈克医疗电子有限公司 Control method, device, equipment and medium for sample detection device
CN113391082A (en) * 2021-06-25 2021-09-14 湖南友哲科技有限公司 Full-automatic comprehensive analysis all-in-one machine for urine and full-automatic urine detection and analysis system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112782420A (en) * 2020-12-30 2021-05-11 迈克医疗电子有限公司 Control method, device, equipment and medium for sample detection device
CN112782420B (en) * 2020-12-30 2024-01-12 迈克医疗电子有限公司 Control method, device, equipment and medium of sample detection device
CN113391082A (en) * 2021-06-25 2021-09-14 湖南友哲科技有限公司 Full-automatic comprehensive analysis all-in-one machine for urine and full-automatic urine detection and analysis system

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Application publication date: 20200717