CN111420720A - Liquid transfer equipment - Google Patents

Liquid transfer equipment Download PDF

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Publication number
CN111420720A
CN111420720A CN202010378050.9A CN202010378050A CN111420720A CN 111420720 A CN111420720 A CN 111420720A CN 202010378050 A CN202010378050 A CN 202010378050A CN 111420720 A CN111420720 A CN 111420720A
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CN
China
Prior art keywords
plate group
slot
chuck mechanism
vertical direction
tray
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010378050.9A
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Chinese (zh)
Inventor
孙刘涛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou HYC Technology Co Ltd
Original Assignee
Suzhou HYC Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou HYC Technology Co Ltd filed Critical Suzhou HYC Technology Co Ltd
Priority to CN202010378050.9A priority Critical patent/CN111420720A/en
Publication of CN111420720A publication Critical patent/CN111420720A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/50Clamping means, tongs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/54Supports specially adapted for pipettes and burettes

Abstract

The invention relates to the technical field of liquid transfer, and discloses a liquid transfer device which comprises a liquid transfer pipe, a liquid transfer mechanism, an installation frame and two chuck mechanisms. The pipette includes a tube, a tip, and a plunger. The liquid-transfering mechanism includes upper plate group and lower plate group, and the upper end of plunger is installed in upper plate group, and the body is installed in lower plate group. The two chuck mechanisms are arranged on the mounting frame in a liftable manner along the vertical direction, the upper plate group is detachably clamped on the upper chuck mechanism, and the lower plate group is detachably clamped on the lower chuck mechanism; the upper chuck mechanism can drive the plunger to lift along the vertical direction through the upper plate group so as to ensure that the gun head absorbs or discharges liquid; the chuck mechanism of below can drive the chuck mechanism of top and go up and down along vertical direction to adjust the height of pipette in vertical direction. This move liquid equipment not only is convenient for install fixedly to the pipette, can accomplish the adjustment of imbibition, flowing back and high position moreover to be favorable to improve equipment's work efficiency.

Description

Liquid transfer equipment
Technical Field
The invention relates to the technical field of liquid transfer, in particular to a liquid transfer device.
Background
In the fields of disease control, food safety, forensic identification, and the like, liquid transfer is typically accomplished using pipetting devices. However, the prior pipetting device is generally inconvenient for mounting and fixing the pipette and has low working efficiency.
Therefore, there is a need for a new type of pipetting device to solve the above mentioned technical problems.
Disclosure of Invention
The invention aims to provide a liquid transfer device which can facilitate the mounting and fixing of a liquid transfer pipe and improve the working efficiency.
In order to achieve the purpose, the invention adopts the following technical scheme:
a pipetting apparatus comprising:
the pipette comprises a pipe body, a pipette head and a plunger, wherein the pipette head is installed at the lower end of the pipe body, and the plunger is slidably arranged in the pipe body in a penetrating manner;
the liquid transfer mechanism comprises an upper plate group and a lower plate group, the upper end of the plunger is installed in the upper plate group, and the pipe body is installed in the lower plate group;
a mounting frame;
the two chuck mechanisms are arranged on the mounting frame in a vertically lifting manner, the upper plate group is detachably clamped on the chuck mechanism above, and the lower plate group is detachably clamped on the chuck mechanism below; the chuck mechanism above can drive the plunger piston to lift along the vertical direction through the upper plate group so as to enable the gun head to suck or discharge liquid; the lower chuck mechanism can drive the upper chuck mechanism to lift along the vertical direction so as to adjust the height of the pipette in the vertical direction.
As the preferable scheme of the liquid removing equipment, the liquid removing equipment further comprises a chuck slide rail and chuck slide blocks which are in sliding fit, the chuck slide rail is installed on the installation frame along the vertical direction, at least two chuck slide blocks are arranged on the chuck slide rail along the vertical direction, and each chuck mechanism is connected with at least one chuck slide block.
As a preferable scheme of the pipetting device, the chuck mechanism includes a clamping plate, the clamping plate is installed on the mounting frame in a manner of being lifted up and down along the vertical direction, a clamping groove is formed in the clamping plate, and the upper plate group or the lower plate group can be inserted into the clamping groove.
As a preferable scheme of the liquid removing apparatus, the clamping groove is a wedge-shaped groove, and the chuck mechanism further includes a wedge block, the wedge block is disposed corresponding to the clamping groove and is inserted into the clamping groove in a position-adjustable manner, so that the upper plate group or the lower plate group is fixed in the clamping groove.
As a preferable scheme of the liquid removing device, the chuck mechanism further comprises an adjusting piece, a first end of the adjusting piece is connected with the wedge block, a second end of the adjusting piece is connected with the clamping plate, and the adjusting piece can drive the wedge block to move along the depth direction of the clamping groove so as to adjust the inserting position of the wedge block in the clamping groove.
As a preferable scheme of the liquid transfer apparatus, an adjusting protrusion is arranged in the clamping groove, an adjusting groove extending in the depth direction of the clamping groove is arranged on the wedge block, the adjusting groove is sleeved on the adjusting protrusion, a second end of the adjusting piece is in threaded connection with the adjusting protrusion, and the first end of the adjusting piece is screwed to drive the wedge block to move in the depth direction of the clamping groove.
As a preferable scheme of the pipetting device, the number of the clamping plates in each clamping head mechanism is two, the two clamping plates are arranged at intervals and oppositely, and the clamping grooves are formed in the inner side walls of the clamping plates.
The liquid transfer apparatus preferably further comprises a tray movably disposed below the chuck mechanism in a first direction, the tray being provided with a plurality of liquid tanks arranged in the first direction, each liquid tank being movable to a position directly below the pipette, so that the gun head sucks liquid from or discharges liquid into the liquid tank.
As the preferred scheme of liquid-transfering equipment, still include the tray slide, the tray slide sets up the below of chuck mechanism, the tray along first direction slidable ground sets up on the tray slide, the bottom of tray is provided with spacing recess, be provided with along the spacing arch of vertical direction telescopic on the tray slide, spacing arch can with spacing recess cooperatees, so that the cistern stops under the pipette.
As a preferable aspect of the pipetting apparatus, the method further comprises:
the first driving mechanism is arranged on the mounting frame, and the driving end of the first driving mechanism is connected with the chuck mechanism below the first driving mechanism so as to drive the chuck mechanism below the first driving mechanism to lift along the vertical direction;
and the driving end of the second driving mechanism is connected with the chuck mechanism above the second driving mechanism so as to drive the chuck mechanism above the second driving mechanism to lift along the vertical direction.
The invention has the beneficial effects that:
according to the liquid transfer equipment provided by the invention, the two chuck mechanisms are utilized to respectively and detachably clamp the upper plate group and the lower plate group, namely, the upper plate group and the lower plate group are fixedly installed on the liquid transfer equipment in a clamping mode, so that the liquid transfer pipe is fixedly installed, the operation is simple, the liquid transfer mechanism and the liquid transfer pipe are convenient to disassemble, and the installation reliability is guaranteed; in addition, through the cooperation of two chuck mechanisms and upper plate group and lower plate group, can also make the pipette accomplish the adjustment of imbibition, flowing back and high position to be favorable to improving pipetting equipment's work efficiency.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments of the present invention will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the contents of the embodiments of the present invention and the drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a pipette provided in an embodiment of the present invention;
fig. 2 is a cross-sectional view of a pipette provided in accordance with an embodiment of the present invention;
FIG. 3 is an enlarged view at A in FIG. 2;
FIG. 4 is a schematic structural diagram of a pipetting mechanism provided by an embodiment of the invention;
FIG. 5 is a first cross-sectional view of a pipetting mechanism provided by an embodiment of the invention;
FIG. 6 is a second cross-sectional view of the pipetting mechanism provided by an embodiment of the invention;
FIG. 7 is a schematic structural diagram of a pipetting device provided by an embodiment of the invention;
FIG. 8 is a schematic view of a first partial structure of a pipetting device provided by an embodiment of the invention;
FIG. 9 is a second partial schematic view of a pipetting device according to an embodiment of the invention;
FIG. 10 is a third partial structural view of the pipetting device provided by the embodiment of the invention;
FIG. 11 is a bottom view of a tray according to an embodiment of the present invention;
fig. 12 is a sectional view of a pipetting apparatus provided by an embodiment of the invention.
In the figure:
1-a pipette; 11-a tube body; 111-a chamber; 112-a seal groove; 12-gun head; 13-a plunger; 14-a first sealing ring; 141-sealing lip; 15-sealing the space; 16-a spacer; 17-a second sealing ring;
2-a pipetting mechanism; 21-upper plate group; 211-upper fixing plate; 2111-first mounting hole; 212-upper liner plate; 2121-a second mounting hole; 2122-a third mounting hole; 22-lower plate group; 221-lower fixing plate; 2211-step mounting hole; 2212-first rod withdrawing hole; 222-a lower liner plate; 2221-a fourth mounting hole; 23-withdrawing the plate assembly; 231-retreating the rod; 232-withdrawing the plate; 2321-step plate hole withdrawing; 233-a reset piece; 234-sleeve; 24-an adjusting plunger; 25-a sealing ring; 26-an auxiliary plate; 261-a pilot hole; 262-second rod withdrawing hole;
3-mounting a frame;
4-a chuck mechanism; 41-clamping plate; 411-a clamping slot; 412-adjustment projection; 42-wedge block; 421-a regulating tank; 43-an adjustment member; 44-a connecting plate;
51-a chuck slide rail; 52-collet slide;
6-a tray; 61-a liquid bath; 62-a stop;
7-a pallet slide; 71-a guide;
8-a first drive mechanism; 81-a first driver; 82-a first lead screw; 83-a first nut seat;
9-a second drive mechanism; 91-a second driver; 92-a second lead screw; 93-second nut seat.
Detailed Description
In order to make the technical problems solved, technical solutions adopted and technical effects achieved by the present invention clearer, the technical solutions of the embodiments of the present invention will be described in further detail below with reference to the accompanying drawings, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like are used for descriptive purposes only or to distinguish between different structures or components and are not to be construed as indicating or implying relative importance. Wherein the terms "first position" and "second position" are two different positions.
In the description of the present invention, it should be noted that unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection or a removable connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
As shown in fig. 1 to 3, the present embodiment provides a pipette 1, and the pipette 1 includes a tube 11, a tip 12, a plunger 13, and a first sealing ring 14. A chamber 111 is provided in the tube 11. The lance tip 12 is mounted at the lower end of the tubular body 11 and communicates with the chamber 111. A plunger 13 is slidably disposed through the chamber 111 in the direction of extension of the chamber 111 to aspirate or expel fluid from the lance tip 12. At least two first sealing rings 14 are arranged between the plunger 13 and the tube body 11, at least two sealing lips 141 are arranged on the first sealing ring 14, at least one sealing lip 141 is abutted with the plunger 13, and at least another sealing lip 141 is abutted with the tube body 11.
According to the pipette 1 provided by the embodiment, at least two first sealing rings 14 are arranged between the plunger 13 and the tube body 11, and at least two sealing lips 141 are arranged on the first sealing ring 14, so that the sealing performance between the plunger 13 and the tube body 11 can be effectively ensured through the matching of the two first sealing rings 14 and the at least two sealing lips 141 in each first sealing ring 14, and the pipette 1 can accurately and quantitatively suck and discharge liquid.
Specifically, in the present embodiment, the number of the first seal rings 14 is two. Of course, in other embodiments, the number of the first sealing rings 14 may also be three or four, etc., and is not limited herein.
Optionally, the at least two first seal rings 14 are one or more of X-seal rings, Y-seal rings, or V-seal rings. In this embodiment, the two first seal rings 14 may be the same type of seal ring, or may be different types of seal rings, for example, both the two first seal rings 14 are X-type seal rings, or one first seal ring 14 is an X-type seal ring, and the other is a Y-type seal ring, etc., the combination type of the two first seal rings 14 may be any combination type, which is not limited herein, and in addition, when the two first seal rings are Y-type seal rings or V-type seal rings, the opening direction of the Y-type seal ring or V-type seal ring is also not limited.
Preferably, as shown in fig. 3, two adjacent first sealing rings 14 are spaced apart to form a sealing space 15. Further, a lubricating fluid is provided in the sealed space 15. The lubricating liquid in the sealed space 15 can play a role of liquid sealing, thereby being beneficial to further improving the sealing effect between the plunger 13 and the tube body 11.
Optionally, as shown in fig. 3, the pipette 1 further includes a spacer 16, and the spacer 16 is disposed between two adjacent first sealing rings 14 to maintain the two adjacent first sealing rings 14 at a spacing. By providing the spacer 16, it is advantageous to ensure the dimensional stability of the sealed space 15, and thus to prevent the lubricating liquid in the sealed space 15 from overflowing. Specifically, in the present embodiment, the spacer 16 is an annular spacer.
Specifically, the upper end of the pipe body 11 is provided with a sealing groove 112, and at least two first sealing rings 14 are disposed in the sealing groove 112. The sealing groove 112 is advantageous for preventing the first sealing ring 14 from being displaced, and ensures the position stability of the first sealing ring 14.
Preferably, as shown in fig. 2, the pipette 1 further comprises a second sealing ring 17, at least two second sealing rings 17 being arranged between the tip 12 and the tubular body 11. The second sealing ring 17 is advantageous in ensuring the sealing between the lance tip 12 and the tubular body 11. Specifically, in the present embodiment, the second seal ring 17 is an O-ring seal. Further, in the present embodiment, the number of the second seal rings 17 is two.
Optionally, the lower end of the tube 11 is provided with an outer conical surface, and the upper end of the gun head 12 is provided with an inner conical surface, where the outer conical surface can be attached to the inner conical surface. Through setting up outer conical surface and interior conical surface, can be convenient for the grafting cooperation of rifle head 12 and body 11.
As shown in fig. 4-6, the present embodiment further provides a pipetting mechanism 2 for mounting the above-mentioned pipette 1, and the pipetting mechanism 2 includes an upper plate group 21, a lower plate group 22 and a back plate group 23. The upper ends of the plungers 13 are mounted in the upper plate group 21. The tubes 11 are mounted in the lower plate group 22. The withdrawing plate assembly 23 comprises a withdrawing rod 231 and a withdrawing plate 232, the first end of the withdrawing rod 231 penetrates through the lower plate group 22 in a liftable mode along the vertical direction, the second end of the withdrawing rod 231 is connected with the withdrawing plate 232, and the withdrawing plate 232 can be abutted to the upper end face of the gun head 12. The upper plate set 21 can bring the plunger 13 to move upwards so as to suck the gun heads 12. The upper plate set 21 can move the plunger 13 downwards to discharge liquid from the gun head 12. The upper plate group 21 continues to move downwards and can be abutted against the first end of the withdrawing rod 231, and the withdrawing rod 231 drives the withdrawing plate 232 to push the upper end face of the gun head 12 downwards, so that the gun head 12 is separated from the tube body 11.
When liquid is required to be absorbed, the lower plate group 22 is fixed, namely the pipe body 11 is kept still, and the upper plate group 21 independently drives the plunger 13 to move upwards, so that the gun head 12 absorbs liquid; when liquid drainage is needed, the lower plate group 22 is fixed, the upper plate group 21 drives the plunger 13 to move downwards (at the moment, the upper plate group 21 is not in contact with the withdrawing rod 231), and the gun head 12 drains liquid; when the lance head 12 needs to be taken down from the pipe body 11, the lower plate group 22 is fixed, the upper plate group 21 continues to move downwards and pushes the withdrawing rod 231, so that the withdrawing rod 231 drives the withdrawing plate 232 to move downwards and pushes the lance head 12 to move downwards, and the separation of the lance head 12 and the pipe body 11 is realized.
According to the liquid transfer mechanism 2 provided by the embodiment, the upper end of the plunger 13 is arranged in the upper plate group 21, and the pipe body 11 is arranged in the lower plate group 22, so that the installation reliability can be ensured, and the plunger 13 and the pipe body 11 can be independently disassembled and assembled, when the pipette 1 needs to be maintained, for example, when a sealing ring is replaced, the whole pipette 1 does not need to be taken out of the liquid transfer mechanism 2, and only the lower plate group 22 needs to be independently disassembled, so that the disassembling and assembling process can be simplified, and the sealing ring can be replaced more simply and conveniently; in addition, the cooperation between the upper plate group 21 and the lower plate group 22 and the retreat plate group 23 enables the pipette tip 12 to be smoothly detached from the tube 11, which is advantageous for improving the working efficiency of the liquid transfer mechanism 2.
In this embodiment, a plurality of pipettes 1 are mounted in a rectangular array on the pipetting mechanism 2.
Specifically, in the present embodiment, the number of the retreat bars 231 is four, and the four retreat bars 231 are respectively located at four corners of the retreat plate 232. Of course, in other embodiments, the number and distribution positions of the backing rods 231 may also be adjusted according to actual requirements, and are not limited herein.
Optionally, a buffer member is provided at an upper end of the withdrawing rod 231 to prevent a hard collision between the upper plate group 21 and the withdrawing rod 231. Specifically, the buffer may be a rubber pad or the like.
As shown in fig. 5, the upper plate group 21 provided in the present embodiment includes an upper fixing plate 211 and an upper liner plate 212. An upper mounting groove with an upward opening is formed in the upper fixing plate 211, a first mounting hole 2111 is formed in the bottom of the upper mounting groove, the plunger 13 penetrates through the first mounting hole 2111, and a flange at the upper end of the plunger 13 can abut against the inner bottom surface of the upper mounting groove. The upper liner 212 is mounted in the upper mounting groove, the upper liner 212 is provided with a second mounting hole 2121, the second mounting hole 2121 is coaxial with the first mounting hole 2111, and a flange of an upper end of the plunger 13 is disposed in the second mounting hole 2121. The flange at the upper end of the plunger 13 is clamped between the upper fixing plate 211 and the upper liner plate 212, so that the upper plate group 21 can drive the plunger 13 to move up and down.
In this embodiment, the pipetting mechanism 2 further includes an adjusting plunger 24, the upper liner 212 is provided with a third mounting hole 2122, the third mounting hole 2122 is coaxial with and communicates with the second mounting hole 2121, and the adjusting plunger 24 can be inserted into the third mounting hole 2122 and pressed against the top of the plunger 13, so that the flange of the plunger 13 abuts against the inner bottom surface of the upper mounting groove. Specifically, in the present embodiment, the adjusting plunger 24 is screwed into the third mounting hole 2122, and the adjusting plunger 24 can be pressed against the top of the plunger 13 by screwing, so that the flange of the plunger 13 is tightly attached to the inner bottom surface of the upper mounting groove, thereby preventing a mounting gap between the two and ensuring the mounting accuracy of the plunger 13.
The lower plate set 22 provided in this embodiment includes a lower fixing plate 221 and a lower liner plate 222. The lower fixing plate 221 is provided with a lower mounting groove with a downward opening, the top of the lower mounting groove is provided with a step mounting hole 2211, the flange at the upper end of the tube body 11 is arranged in the step mounting hole 2211, the top surface of the flange is abutted against the step surface of the step mounting hole 2211, and the plunger 13 can pass through the step mounting hole 2211 and be inserted into the tube body 11. The lower liner 222 is mounted in the lower mounting groove, the lower liner 222 is provided with a fourth mounting hole 2221, the fourth mounting hole 2221 is coaxial with the step mounting hole 2211, the pipe body 11 is inserted into the fourth mounting hole 2221, and the bottom surface of the upper end flange of the pipe body abuts against the lower liner 222. The flange of the upper end of the pipe 11 is between the lower fixing plate 221 and the lower liner plate 222, so that the lower plate set 22 can move the pipe 11 up and down.
Preferably, the pipetting mechanism 2 provided by the present embodiment further comprises a sealing ring 25, and the sealing ring 25 is disposed between the lower fixing plate 221 and the tube 11. The sealing ring 25 is advantageous to ensure the sealing performance between the lower fixing plate 221 and the pipe body 11. Optionally, the seal ring 25 is an O-ring seal.
The pipetting mechanism 2 provided by the present embodiment further comprises an auxiliary plate 26, the auxiliary plate 26 is connected to the lower fixing plate 221 and is located below the lower fixing plate 221, the auxiliary plate 26 is provided with a guide hole 261, and the tube 11 is inserted into the guide hole 261. The guide hole 261 is advantageous for preventing the pipe body 11 from shaking in the lifting process, and the accuracy of the lifting path of the pipe body 11 is ensured.
Specifically, in the present embodiment, the top surface of the auxiliary plate 26 abuts against the bottom surface of the lower liner plate 222 to fix the lower liner plate 222 in the lower mounting groove, ensuring stability and reliability of mounting of the lower liner plate 222.
As shown in fig. 6, preferably, the withdrawing plate assembly 23 further includes a restoring member 233, and the restoring member 233 is sleeved on the withdrawing rod 231 and can push the withdrawing rod 231 to restore. The restoring members 233 are provided in one-to-one correspondence with the returning levers 231, and in the present embodiment, the number of the restoring members 233 is four. Specifically, in the present embodiment, the restoring member 233 is a restoring spring.
Further, a first rod retreating hole 2212 is formed in the lower fixing plate 221, a second rod retreating hole 262 is formed in the auxiliary plate 26, the first rod retreating hole 2212 is coaxial with the second rod retreating hole 262, the rod retreating 231 is arranged in the first rod retreating hole 2212 and the second rod retreating hole 262 in a penetrating mode in a vertically liftable mode, the resetting piece 233 is sleeved on the rod retreating 231, the upper end of the resetting piece 233 is abutted to a flange at the upper end of the rod retreating 231, and the lower end of the resetting piece 233 is abutted to the bottom face of the second rod retreating hole 262. The restoring member 233 can push the flange of the upper end of the withdrawing rod 231 upward to restore the withdrawing rod 231 upward. In the present embodiment, the restoring member 233 is mounted in the second lever returning hole 262 of the auxiliary plate 26, but in other embodiments, the restoring member 233 may be mounted on the lower fixing plate 221 without limitation as long as the restoring lever 231 can be restored.
Optionally, as shown in fig. 5, a stepped returning plate hole 2321 is provided on the returning plate 232, and a stepped surface of the stepped returning plate hole 2321 can abut against an upper end surface of the lance head 12 to push the lance head 12 to separate from the tube 11. The step surface of the step back plate hole 2321 can be uniformly contacted with the circumferential direction of the upper end surface of the gun head 12, so that the upper end surface of the gun head 12 is uniformly stressed, and the gun head 12 can be favorably separated from the tube body 11 smoothly.
Note that, in the present embodiment, since a plurality of pipettes 1 are arranged in a rectangular array on the pipetting mechanism 2, the various mounting holes on the upper plate group 21, the lower plate group 22, the auxiliary plate 26, and the retreat plate 232 are also arranged in a rectangular array.
Optionally, in this embodiment, a number is provided on an edge of the bottom surface of the returning plate 232, and the number is provided in one-to-one correspondence with the step returning plate hole 2321 on the outermost circle in the rectangular array, so as to identify the row and the column where the pipette 1 is located.
As shown in fig. 4-6, the withdrawing plate assembly 23 of the present embodiment further includes a sleeve 234, the sleeve 234 is sleeved on the lower end of the withdrawing rod 231, and the upper end of the sleeve 234 can abut against the bottom surface of the auxiliary plate 26 to limit the upward moving stroke of the withdrawing rod 231. The sleeves 234 are provided in one-to-one correspondence with the retreat bars 231, and in the present embodiment, the number of the sleeves 234 is four.
As shown in fig. 7 to 9 in conjunction with fig. 1 and 4, the present embodiment also provides a pipetting apparatus including a pipette 1, a pipetting mechanism 2, a mounting frame 3, and two chuck mechanisms 4. The pipette 1 comprises a tube 11, a tip 12 and a plunger 13, wherein the tip 12 is mounted at the lower end of the tube 11, and the plunger 13 is slidably inserted into the tube 11. The pipetting mechanism 2 comprises an upper plate group 21 and a lower plate group 22, the upper end of the plunger 13 is mounted in the upper plate group 21, and the tube 11 is mounted in the lower plate group 22. The two chuck mechanisms 4 are arranged on the mounting frame 3 in a vertically lifting manner, the upper plate group 21 is detachably clamped on the upper chuck mechanism 4, and the lower plate group 22 is detachably clamped on the lower chuck mechanism 4; the upper chuck mechanism 4 can drive the plunger 13 to lift in the vertical direction through the upper plate group 21 so as to enable the gun head 12 to suck or discharge liquid; the lower chuck mechanism 4 can drive the upper chuck mechanism 4 to lift vertically so as to adjust the height of the pipette 1 in the vertical direction.
When liquid needs to be absorbed, the lower chuck mechanism 4 drives the upper chuck mechanism 4 to move in the vertical direction to integrally adjust the pipette 1 to the liquid absorption position, then the lower chuck mechanism 4 is fixed, namely the lower plate group 22 and the tube body 11 are kept stationary, and the upper chuck mechanism 4 drives the plunger 13 to move upwards through the upper plate group 21 independently to absorb liquid by the gun head 12; when liquid needs to be discharged, the lower chuck mechanism 4 drives the upper chuck mechanism 4 to move in the vertical direction to integrally adjust the pipette 1 to the liquid discharge position, then the lower chuck mechanism 4 is fixed, and the upper chuck mechanism 4 drives the upper plate group 21 and the plunger 13 to move downwards (at this time, the upper plate group 21 is not in contact with the retreating rod 231), so that the pipette head 12 discharges liquid; when the gun head 12 needs to be taken down from the tube body 11, the lower chuck mechanism 4 is fixed, the upper chuck mechanism 4 continues to move downwards and enables the upper plate group 21 to push the withdrawing rod 231, and meanwhile, the withdrawing rod 231 drives the withdrawing plate 232 to move downwards and pushes the gun head 12 to move downwards, so that the gun head 12 is separated from the tube body 11.
According to the liquid transfer equipment provided by the embodiment, the two chuck mechanisms 4 are used for respectively and detachably clamping the upper plate group 21 and the lower plate group 22, namely, the upper plate group 21 and the lower plate group 22 are fixedly installed on the liquid transfer equipment in a clamping mode, and further the liquid transfer pipe 1 is fixedly installed, so that the operation is simple, the liquid transfer mechanism 2 and the liquid transfer pipe 1 are convenient to detach, and the installation reliability of the upper plate group 21 and the lower plate group 22 is ensured; in addition, through the cooperation of the two chuck mechanisms 4 and the upper plate group 21 and the lower plate group 22, the pipette 1 can complete liquid suction, liquid discharge and height position adjustment, thereby being beneficial to improving the working efficiency of the pipetting equipment.
Preferably, as shown in fig. 9, the chuck mechanism 4 includes a clamping plate 41, the clamping plate 41 is vertically installed on the mounting frame 3 in a liftable manner, a clamping slot 411 is formed in the clamping plate 41, and the upper plate group 21 or the lower plate group 22 can be inserted into the clamping slot 411. Specifically, in the present embodiment, flanges are provided on both the upper fixing plate 211 and the lower fixing plate 221, and the flanges can be inserted into the clip slots 411.
In this embodiment, the number of the clamping plates 41 in each chuck mechanism 4 is two, the two clamping plates 41 are spaced and arranged oppositely, and the clamping slot 411 is opened on the inner side wall of the clamping plate 41. The two clamping slots 411 of the two clamping plates 41 can respectively clamp the two ends of the upper plate set 21 or the lower plate set 22, so as to ensure the stability of clamping and avoid the interference between the clamping plates 41 and the pipette 1. Of course, in other embodiments, a clamping plate 41 may be provided in each chuck mechanism 4, and a through-shaped clamping slot 411 may be formed in the clamping plate 41, so that the clamping function may be achieved by clamping the middle portion of the upper plate set 21 or the lower plate set 22.
In this embodiment, the clamping slot 411 is a wedge-shaped slot, and the chuck mechanism 4 further includes a wedge 42, wherein the wedge 42 is disposed corresponding to the clamping slot 411 and is inserted into the clamping slot 411 in a position adjustable manner, so that the upper plate set 21 or the lower plate set 22 is fixed in the clamping slot 411. By adjusting the insertion depth of the wedge 42 into the clip slot 411, it is not only advantageous to prevent a movable gap from being left between the upper plate group 21 or the lower plate group 22 and the slot surface of the clip slot 411 so that the upper plate group 21 or the lower plate group 22 is stably clipped in the clip slot 411, but also to facilitate the removal of the upper plate group 21 or the lower plate group 22 from the clip slot 411.
Specifically, in the present embodiment, each clamping plate 41 is provided with one clamping slot 411, that is, the number of the clamping slots 411 is four, and the number of the wedges 42 corresponding to the clamping slots 411 is also four.
The chuck mechanism 4 provided by this embodiment further includes an adjusting member 43, a first end of the adjusting member 43 is connected to the wedge 42, a second end of the adjusting member 43 is connected to the clamping plate 41, and the adjusting member 43 can drive the wedge 42 to move along the depth direction of the clamping slot 411, so as to adjust the inserting position of the wedge 42 in the clamping slot 411. That is, the insertion position of the wedge 42 in the clip slot 411 is adjusted by the adjusting member 43.
Preferably, an adjusting protrusion 412 is disposed in the clamping slot 411, an adjusting slot 421 extending along the depth direction of the clamping slot 411 is disposed on the wedge 42, the adjusting slot 421 is sleeved on the adjusting protrusion 412, the second end of the adjusting member 43 is in threaded connection with the adjusting protrusion 412, and the first end of the adjusting member 43 is screwed to drive the wedge 42 to move along the depth direction of the clamping slot 411. By screwing the adjusting member 43, the adjusting member 43 can move relative to the adjusting protrusion 412 along the depth direction of the clamping slot 411, so as to drive the wedge 42 to move, and the wedge 42 fixes the upper plate group 21 or the lower plate group 22 in the clamping slot 411.
Preferably, as shown in fig. 8, the pipetting device provided by the present embodiment further includes a cartridge slide rail 51 and a cartridge slide block 52 which are slidably fitted, the cartridge slide rail 51 is mounted on the mounting frame 3 in the vertical direction, at least two cartridge slide blocks 52 are arranged on the cartridge slide rail 51 in the vertical direction, and each cartridge mechanism 4 is connected to at least one cartridge slide block 52. The cooperation of the collet slide rail 51 and the collet slide block 52 is beneficial to ensuring the stability of the lifting of the collet mechanism 4 and the accuracy of the lifting path. In addition, in the present embodiment, the two chuck mechanisms 4 adopt a common rail design, that is, share the same chuck slide rail 51, so as to facilitate simplifying the structure of the equipment, improve the compactness of the structure, and reduce the cost of the equipment.
Specifically, in the present embodiment, two collet slide rails 51 are arranged in parallel at intervals, two collet slide blocks 52 are arranged on each collet slide rail 51, that is, the number of collet slide blocks 52 is four, and the collet slide blocks 52 are connected to the clamping plates 41 in a one-to-one correspondence manner.
As shown in fig. 7, 8 and 10, the pipetting apparatus provided in this embodiment further includes a tray 6, the tray 6 is movably disposed below the chuck mechanism 4 along the first direction, a plurality of liquid tanks 61 arranged along the first direction are disposed on the tray 6, and each liquid tank 61 can move to a position right below the pipette 1, so that the tip 12 sucks liquid from the liquid tank 61 or discharges liquid into the liquid tank 61. Specifically, in the present embodiment, the number of the liquid tanks 61 is three. After the liquid is completely absorbed by the gun head 12 in the first liquid tank 61, the lower chuck mechanism 4 drives the upper chuck mechanism 4 to move upwards to prevent the tray 6 from interfering with the pipette 1 when moving, then the tray 6 is pushed to move the second liquid tank 61 to the lower part of the gun head 12, and then the gun head 12 can discharge liquid into the second liquid tank 61. It should be noted that, in this embodiment, the structure of the bottom of the tray 6 in fig. 7 is slightly different from that of the bottom of the tray 6 in fig. 8, but the liquid grooves 61 are arranged on the bottom of the tray, and the liquid grooves can be matched with the pipettes 1 to complete pipetting.
The present embodiment provides that the edges of the tray 6 are provided with numbers identifying the row and column in which the pipette 1 is located.
The liquid-transfering equipment that this embodiment provided still includes tray slide 7, and tray slide 7 sets up in chuck mechanism 4's below, and tray 6 sets up on tray slide 7 along first direction slidable, and the bottom of tray 6 is provided with spacing recess, is provided with on the tray slide 7 along the spacing arch of vertical direction telescopic, and spacing arch can cooperate with spacing recess to make cistern 61 stop under pipette 1. Spacing arch can adopt ball and spring matched with structure, and the ball setting is on the top of spring, when tray 6 need remove, promotes tray 6 and can make the spring compression to make tray 6 can remove smoothly, after tray 6 removes to the right place, the ball falls into spacing recess, and the spring extension, thereby makes tray 6 stop under pipette 1.
In this embodiment, the tray 6 is moved by being manually pushed, but in other embodiments, the tray 6 may be moved by a structure such as an electric sliding table, and the like, which is not limited herein.
Alternatively, as shown in fig. 11, the limiting member 62 is disposed at the bottom of the tray 6, the tray slide 7 is disposed with a guide member 71 engaged with the limiting member 62, and when the tray 6 is disassembled, the limiting member 62 rotates 90 ° so that the limiting member 62 can pass through the inner hole of the guide member 71, thereby replacing the tray 6; after replacement, the limiting member 62 rotates 90 ° in the opposite direction, so that the limiting member 72 cannot pass through the inner hole of the guide member 71, thereby realizing limiting.
As shown in fig. 8 and fig. 12, the pipetting device provided in this embodiment further includes a first driving mechanism 8 and a second driving mechanism 9, the first driving mechanism 8 is mounted on the mounting frame 3, and a driving end of the first driving mechanism is connected to the lower chuck mechanism 4, so as to drive the lower chuck mechanism 4 to lift and lower along a vertical direction. The driving end of the second driving mechanism 9 is connected with the upper chuck mechanism 4 to drive the upper chuck mechanism 4 to lift along the vertical direction.
Specifically, in this embodiment, as shown in fig. 12, the first driving mechanism 8 includes a first driver 81, a first lead screw 82, and a first nut seat 83, the first driver 81 is installed on the mounting frame 3, the first lead screw 82 extends in the vertical direction and is in transmission connection with a driving end of the first driver 81, the first nut seat 83 is fixedly installed on the connecting plate 44 of the lower chuck mechanism 4, and the first driver 81 can drive the first lead screw 82 to rotate and enable the first nut seat 83 to drive the lower chuck mechanism 4 to move in the vertical direction.
Further, the first lead screw 82 is in transmission connection with the driving end of the first driver 81 through a transmission belt and a transmission wheel.
As shown in fig. 12, in this embodiment, the second driving mechanism 9 includes a second driver 91, a second lead screw 92 and a second nut seat 93, the second driver 91 is fixedly installed on the connecting plate 44 of the upper chuck mechanism 4, the second lead screw 92 extends in the vertical direction and is in transmission connection with the driving end of the second driver 91, the second nut seat 93 is fixedly installed on the connecting plate 44 of the lower chuck mechanism 4, and the second driver 91 can drive the second lead screw 92 to rotate, so that the second lead screw 92 drives the upper chuck mechanism 4 and the second driver 91 to move in the vertical direction. That is, the first lead screw 82 in the first driving mechanism 8 is not changed in position, and the first nut holder 83 is raised and lowered in the vertical direction, and the second nut holder 93 in the second driving mechanism 9 is not changed in position, and the second lead screw 92 is raised and lowered in the vertical direction.
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.

Claims (10)

1. A pipetting apparatus, characterized by comprising:
the pipette (1) comprises a pipe body (11), a gun head (12) and a plunger (13), wherein the gun head (12) is installed at the lower end of the pipe body (11), and the plunger (13) is slidably arranged in the pipe body (11) in a penetrating manner;
a pipetting mechanism (2) comprising an upper plate group (21) and a lower plate group (22), the upper end of the plunger (13) being mounted in the upper plate group (21) and the tube (11) being mounted in the lower plate group (22);
a mounting frame (3);
the two chuck mechanisms (4) are arranged on the mounting rack (3) in a vertically lifting manner, the upper plate group (21) is detachably clamped on the upper chuck mechanism (4), and the lower plate group (22) is detachably clamped on the lower chuck mechanism (4); the chuck mechanism (4) above can drive the plunger (13) to lift in the vertical direction through the upper plate group (21) so as to enable the gun head (12) to suck or discharge liquid; the lower chuck mechanism (4) can drive the upper chuck mechanism (4) to lift along the vertical direction so as to adjust the height of the pipette (1) in the vertical direction.
2. The pipetting apparatus according to claim 1, further comprising a cartridge slide rail (51) and a cartridge slide block (52) which are slidably fitted, wherein the cartridge slide rail (51) is mounted on the mounting rack (3) in the vertical direction, at least two cartridge slide blocks (52) are arranged on the cartridge slide rail (51) in the vertical direction, and each cartridge mechanism (4) is connected to at least one cartridge slide block (52).
3. Pipetting device according to claim 1, characterized in that the collet mechanism (4) comprises a clamping plate (41), the clamping plate (41) being vertically elevatably mounted on the mounting frame (3), the clamping plate (41) being provided with a clamping slot (411), the upper plate group (21) or the lower plate group (22) being insertable in the clamping slot (411).
4. A pipetting apparatus according to claim 3, characterized in that the slot (411) is a wedge-shaped slot, and the chuck mechanism (4) further comprises a wedge (42), the wedge (42) being disposed in correspondence with the slot (411) and being positionally adjustably inserted in the slot (411) to fix the upper plate group (21) or the lower plate group (22) in the slot (411).
5. A pipetting apparatus according to claim 4, characterized in that the gripper mechanism (4) further comprises an adjustment member (43), the adjustment member (43) being connected at a first end to the wedge (42) and at a second end to the clamping plate (41), the adjustment member (43) being capable of moving the wedge (42) in the depth direction of the gripper slot (411) for adjusting the insertion position of the wedge (42) in the gripper slot (411).
6. A pipetting apparatus as recited in claim 5, characterized in that an adjusting protrusion (412) is disposed in the holder slot (411), an adjusting slot (421) extending in the depth direction of the holder slot (411) is disposed on the wedge (42), the adjusting slot (421) is sleeved on the adjusting protrusion (412), the second end of the adjusting member (43) is in threaded connection with the adjusting protrusion (412), and screwing the first end of the adjusting member (43) can drive the wedge (42) to move in the depth direction of the holder slot (411).
7. A pipetting apparatus according to claim 3 characterized in that the number of said jaws (41) in each of said collet means (4) is two, two of said jaws (41) are spaced and oppositely disposed, and said jaw slot (411) opens on the inner side wall of said jaws (41).
8. A pipetting apparatus as recited in claim 3 further comprising a tray (6), wherein the tray (6) is movably disposed below the chuck mechanism (4) in a first direction, and wherein the tray (6) is provided with a plurality of liquid tanks (61) arranged in the first direction, and wherein each of the liquid tanks (61) is movable to a position directly below the pipette (1) so that the tips (12) are sucked from the liquid tanks (61) or discharged into the liquid tanks (61).
9. The pipetting apparatus according to claim 8, characterized by further comprising a tray slide (7), wherein the tray slide (7) is disposed below the chuck mechanism (4), the tray (6) is slidably disposed on the tray slide (7) along the first direction, a limiting groove is disposed at the bottom of the tray (6), a limiting protrusion which is retractable along the vertical direction is disposed on the tray slide (7), and the limiting protrusion can be matched with the limiting groove to make the liquid tank (61) stay right below the pipette (1).
10. The pipette device according to claim 1, characterized by further comprising:
the first driving mechanism (8) is arranged on the mounting frame (3), and the driving end of the first driving mechanism is connected with the chuck mechanism (4) below the first driving mechanism so as to drive the chuck mechanism (4) below the first driving mechanism to lift along the vertical direction;
and the driving end of the second driving mechanism (9) is connected with the chuck mechanism (4) above so as to drive the chuck mechanism (4) above to lift along the vertical direction.
CN202010378050.9A 2020-05-07 2020-05-07 Liquid transfer equipment Pending CN111420720A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010378050.9A CN111420720A (en) 2020-05-07 2020-05-07 Liquid transfer equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010378050.9A CN111420720A (en) 2020-05-07 2020-05-07 Liquid transfer equipment

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Application Number Title Priority Date Filing Date
CN202010378050.9A Pending CN111420720A (en) 2020-05-07 2020-05-07 Liquid transfer equipment

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Country Link
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113908899A (en) * 2021-09-17 2022-01-11 圣湘生物科技股份有限公司 Liquid transfer device, nucleic acid extraction and detection device, and liquid transfer device replacement method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113908899A (en) * 2021-09-17 2022-01-11 圣湘生物科技股份有限公司 Liquid transfer device, nucleic acid extraction and detection device, and liquid transfer device replacement method

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