CN111418844A - Bamboo leaf flavone tablet and preparation method thereof - Google Patents

Bamboo leaf flavone tablet and preparation method thereof Download PDF

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Publication number
CN111418844A
CN111418844A CN202010399493.6A CN202010399493A CN111418844A CN 111418844 A CN111418844 A CN 111418844A CN 202010399493 A CN202010399493 A CN 202010399493A CN 111418844 A CN111418844 A CN 111418844A
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China
Prior art keywords
parts
bamboo leaf
leaf flavone
tablet
preparing
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CN202010399493.6A
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Chinese (zh)
Inventor
徐德锋
龚顺泽
胡航
周欢
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Jiangsu Huibo Biotechnology Co ltd
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Jiangsu Huibo Biotechnology Co ltd
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Priority to CN202010399493.6A priority Critical patent/CN111418844A/en
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
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    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
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Abstract

The invention discloses a bamboo leaf flavone tablet and a preparation method thereof, wherein the bamboo leaf flavone tablet is prepared from the following raw materials in percentage by mass: 10-30 parts of bamboo leaf flavone, 5-20 parts of corn peptide, 20-40 parts of thickening agent, 5-15 parts of sweetening agent, 5-15 parts of soybean lecithin, 0.5-3 parts of food preservative and 0.5-3 parts of glidant auxiliary material. Mixing the above materials, tabletting by dry method, coating, detecting, and packaging. The bamboo leaf flavone tablet prepared by the formula has the advantages of quick dissolution of the effective ingredients of the bamboo leaf flavone, high bioavailability and better pharmacological effect of the bamboo leaf flavone. After the bamboo leaf flavone tablet candy is taken, the functions of preventing cardiovascular and cerebrovascular diseases, regulating blood fat, reducing blood viscosity, preventing hypertension, protecting liver and gallbladder, enhancing immunity and the like are achieved.

Description

Bamboo leaf flavone tablet and preparation method thereof
Technical Field
The invention relates to a bamboo leaf flavone tablet and a preparation method thereof, in particular to a formula for preparing the bamboo leaf flavone tablet by using bamboo leaf flavone as a raw material and a preparation method thereof, belonging to the technical field of food processing.
Background
With the continuous improvement of living standard of people, the acceleration of life rhythm and the change of diet culture, many people cause blood hypertension, high blood fat, hyperglycemia and other common problems seriously affecting the body health due to learning, living, working pressure and the like. Meanwhile, more and more people pay attention to food health preservation and prevention. The health food has effects of supplementing nutrition and improving life quality.
The bamboo leaf flavone is a natural compound extracted from the lophatherum gracile leaves, contains a large amount of flavone, phenolic acid, anthraquinone compounds and the like, and has the effects of preventing cardiovascular and cerebrovascular diseases, expanding capillary vessels, dredging microcirculation, regulating blood fat, reducing blood viscosity, protecting liver, improving sleep and the like. Bamboo leaf flavone is approved as a new resource food in the country in 2014, and the eating amount is less than or equal to 2 g/day.
The corn oligopeptide is a new resource food approved by the national ministry of health in 2010, and is a micromolecule polypeptide extracted by using corn protein powder as a raw material and utilizing a bioengineering directional enzyme digestion technology. Has effects in lowering blood pressure, reducing blood lipid, reducing cholesterol, relieving fatigue, resisting aging, and protecting liver.
Soybean lecithin is extracted from soybean oil residue, and contains active components such as lecithin, cephalin, inositol phospholipid, and phosphatidylserine. It is mainly used for treating atherosclerosis, acute and chronic hepatitis, fatty liver, liver cirrhosis, neurasthenia, etc.
A polypeptide food containing bamboo leaf flavone (Chinese patent CN 110477396A) is reported to prepare health food from leaf flavone, soybean peptide powder, active Lumbricus protein, radix Puerariae, semen Persicae, etc. Natto bamboo leaf flavone tablet candy (Chinese patent CN 109315576A) reports preparation of Natto bamboo leaf flavone tablet candy by adopting bamboo leaf flavone, natto powder, red yeast rice powder, hydrolyzed collagen powder and other raw materials. A processing technology of bamboo leaf flavone chewable tablets (Chinese patent CNCN 103719840A) reports that the bamboo leaf flavone chewable tablets are prepared by adopting the processing and extraction of the bamboo leaf flavone as raw materials. At present, tablets such as bamboo leaf flavone tablet candies, a plurality of bamboo leaf flavone tablets, bamboo leaf flavone chewable tablets and the like are seen in the market, but functional health food supplements are not used in the food formulas, so that the bioavailability of effective active molecules in the bamboo leaf flavone product is low, the dissolution rate of effective components is slow, the synergistic effect is not fully utilized by combining with the functional health food supplements, and the health care effect of the bamboo leaf flavone can be improved. The invention aims at the bamboo leaf flavone tablet, invents a tablet formula which takes bamboo leaf flavone, corn peptide, soybean lecithin and the like as raw materials, has good bioavailability of bamboo leaf flavone active molecules, can synergistically reduce blood fat, blood pressure and blood sugar, effectively protects cardiovascular and cerebrovascular, protects liver, benefits gallbladder, enhances immune function and the like.
Disclosure of Invention
The purpose is as follows: in order to solve the defects of the prior art, the invention provides the bamboo leaf flavone tablet and the preparation method thereof, and the health food supplements such as corn oligopeptide, soybean lecithin and the like are added, so that the bamboo leaf flavone active molecules have good bioavailability and quick solubility of effective molecules. Has effects of reducing blood lipid, lowering blood pressure, and lowering blood sugar, and is helpful for health recovery.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows: the preparation method of the bamboo leaf flavone tablet is characterized by comprising the following raw materials, by mass, 10-30 parts of bamboo leaf flavone, 5-20 parts of corn peptide, 5-20 parts of a thickening agent, 5-15 parts of a sweetening agent, 5-15 parts of soybean phospholipid, 0.5-3 parts of a food preservative and 0.5-3 parts of a flow aid auxiliary material.
According to the preferable scheme, the bamboo leaf flavone tablet and the preparation method thereof comprise the following raw materials, by mass, 15-25 parts of bamboo leaf flavone, 10-15 parts of corn peptide, 10-15 parts of thickening agent, 8-12 parts of sweetening agent, 8-12 parts of soybean phospholipid, 1-2 parts of food preservative and 1-2 parts of glidant auxiliary materials.
After being uniformly mixed, the mixture is tabletted by a dry method; coating with food-grade coating, vacuum microwave sterilizing, testing, and packaging to obtain folium Bambusae flavone tablet.
Furthermore, the corn peptide is corn oligopeptide powder, and a mixture of various small peptides obtained by degrading corn protein through enzyme reaches a new resource food standard approved by the national ministry of health.
The thickening agent is one or more of maltodextrin, microcrystalline cellulose, corn starch and sodium carboxymethyl cellulose;
the sweetener is one or more of xylo-oligosaccharide, xylitol, maltitol, stevioside and trehalose;
the food preservative is one or more of citric acid, D-sodium erythorbate, malic acid and lactic acid;
the glidant auxiliary materials are one or more of magnesium stearate, micro-powder silica gel and talcum powder.
The food-grade coating agent is one or two of polyethylene glycol or hydroxypropyl methyl cellulose.
The method for preparing the bamboo leaf flavone tablet comprises the following steps:
the ingredients are mixed according to the proportion, the prepared raw materials are added into a mixing machine, the rotating speed is set to be 100-300 r/min, the stirring is carried out for 20-40 min, after the raw materials are uniformly mixed, the dry tabletting and coating are carried out, the vacuum microwave sterilization is carried out, and the bamboo leaf flavonoid tablet is obtained after the detection is qualified.
Has the advantages that: according to the bamboo leaf flavone tablet and the preparation method thereof provided by the invention, a health food supplement such as corn oligopeptide, soybean phospholipid and the like is added, a thickener, a sweetening agent, a food preservative, a glidant auxiliary material and the like are adopted, and a food-grade coating agent is used for coating, the specific proportion and the production process are adopted, the components have a synergistic effect, and the bamboo leaf flavone tablet is prepared by fine processing; the edible food is safe and effective, and is nontoxic and harmless; compared with the existing ginger tablet control product, the solubility of the effective molecule bamboo leaf flavonoid is greatly improved, and the bioavailability of the bamboo leaf flavonoid active molecule is good; the effective active ingredients are dissolved out quickly, the bioavailability is high, the drug effect of the bamboo leaf flavone active molecules which are the effective ingredients can be better exerted, and the medication cost is reduced. The invention has the functions of preventing cardiovascular and cerebrovascular diseases, regulating blood fat, reducing blood viscosity, preventing hypertension, protecting liver and benefiting gallbladder, enhancing immunity and the like, and particularly has the best effect on reducing blood fat and improving the immunity of organisms.
The specific implementation mode is as follows:
example 1: bamboo leaf flavone tablet
30 parts of bamboo leaf flavone, 5 parts of corn peptide (5 parts of corn oligopeptide powder), 20 parts of thickening agent (10 parts of maltodextrin and 10 parts of microcrystalline cellulose), 15 parts of sweetening agent (10 parts of xylo-oligosaccharide and 5 parts of xylitol), 15 parts of soybean phospholipid, 0.5 part of food preservative (0.2 part of citric acid and 0.3 part of D-sodium isoascorbate), and 3 parts of glidant auxiliary materials (1.0 part of magnesium stearate and 2.0 parts of silica gel).
The corn peptide is corn oligopeptide powder;
the thickening agent is a mixture of maltodextrin and microcrystalline cellulose;
the sweetener is a mixture of xylo-oligosaccharide and xylitol.
The food preservative is a mixture of citric acid and D-sodium erythorbate;
the auxiliary materials of the glidant are a mixture of magnesium stearate and aerosil.
The food-grade coating agent is polyethylene glycol.
A bamboo leaf flavone tablet and a preparation method thereof, the method comprises the following processes:
the ingredients are mixed according to the proportion, the prepared raw materials are added into a mixing machine, the rotating speed is set to be 100-300 r/min, the stirring is carried out for 40 min, after the raw materials are uniformly mixed, the dry tabletting is carried out, the food-grade coating agent is polyethylene glycol for coating, the vacuum microwave sterilization is carried out, and after the detection is qualified, the packaging is carried out, thus obtaining the bamboo leaf flavonoid tabletting 1.
Example 2: bamboo leaf flavone tablet
10 parts of bamboo leaf flavone, 20 parts of corn peptide (20 parts of corn oligopeptide powder), 5 parts of thickening agent (2 parts of maltodextrin, 2 parts of microcrystalline cellulose and 1 part of corn starch), 5 parts of sweetening agent (2 parts of maltitol, 2 parts of stevioside and 1 part of trehalose), 5 parts of soybean lecithin, 3 parts of food preservative (2 parts of malic acid and 1 part of lactic acid) and 0.5 part of glidant auxiliary material (0.5 part of magnesium stearate).
The corn peptide is corn oligopeptide powder;
the thickening agent is a mixture of maltodextrin, microcrystalline cellulose and corn starch;
the sweetener is a mixture of maltitol, stevioside and trehalose;
the food preservative is a mixture of malic acid and lactic acid;
the glidant auxiliary material is magnesium stearate.
The food-grade coating agent is a 1:1 mixture of polyethylene glycol and hydroxypropyl methyl cellulose.
A bamboo leaf flavone tablet and a preparation method thereof, the method comprises the following processes:
the ingredients are mixed according to the proportion, the prepared raw materials are added into a mixing machine, the rotating speed is set to be 100-300 r/min, the stirring is carried out for 20 min, the dry tabletting is carried out after the raw materials are uniformly mixed, the food-grade coating agent is the mixture of polyethylene glycol and hydroxypropyl methyl cellulose for coating, the vacuum microwave sterilization is carried out, and the bamboo leaf flavonoid tablet 2 is prepared after the detection is qualified.
Example 3: bamboo leaf flavone tablet
The raw materials comprise, by mass, 10 parts of bamboo leaf flavone, 12 parts of corn peptide (12 parts of corn oligopeptide powder), 12 parts of thickening agent (5 parts of maltodextrin, 5 parts of microcrystalline cellulose and 2 parts of sodium carboxymethylcellulose), 10 parts of sweetening agent (8 parts of xylo-oligosaccharide, 1 part of maltitol and 1 part of trehalose), 10 parts of soybean lecithin, 1.5 parts of food preservative (1.0 part of citric acid and 0.5 part of D-sodium isoascorbate) and 1.5 parts of glidant auxiliary material (1.0 part of magnesium stearate and 0.5 part of talcum powder).
The corn peptide is corn oligopeptide powder;
the thickening agent is a mixture of maltodextrin, microcrystalline cellulose and sodium carboxymethyl cellulose;
the sweetener is a mixture of xylo-oligosaccharide, maltitol and trehalose.
The food preservative is a mixture of citric acid and D-sodium erythorbate;
the glidant auxiliary material is a mixture of magnesium stearate and talcum powder.
The food-grade coating agent is polyethylene glycol.
A bamboo leaf flavone tablet and a preparation method thereof, the method comprises the following processes:
the ingredients are mixed according to the proportion, the prepared raw materials are added into a mixing machine, the rotating speed is set to be 100-300 r/min, the stirring is carried out for 30 min, after the raw materials are uniformly mixed, the dry tabletting is carried out, the food-grade coating agent is polyethylene glycol for coating, the vacuum microwave sterilization is carried out, and after the detection is qualified, the packaging is carried out, thus obtaining the bamboo leaf flavonoid tabletting 3.
Example 4: bamboo leaf flavone tablet
The raw materials comprise, by mass, 20 parts of bamboo leaf flavone, 15 parts of corn peptide (15 parts of corn oligopeptide powder), 15 parts of thickening agent (5 parts of maltodextrin, 5 parts of microcrystalline cellulose and 5 parts of corn starch), 8 parts of sweetening agent (2 parts of xylitol, 4 parts of maltitol and 2 parts of stevioside), 8 parts of soybean lecithin, 2 parts of food preservative (0.5 part of citric acid, 0.5 part of malic acid and 1 part of lactic acid) and 1 part of glidant auxiliary material (1.0 part of magnesium stearate and 0.5 part of superfine silica gel powder).
The corn peptide is corn oligopeptide powder;
the thickening agent is a mixture of maltodextrin, microcrystalline cellulose and corn starch;
the sweetener is a mixture of xylitol, maltitol and stevioside.
The food preservative is a mixture of citric acid, malic acid and lactic acid;
the auxiliary materials of the glidant are a mixture of magnesium stearate and aerosil.
The food-grade coating agent is polyethylene glycol.
A bamboo leaf flavone tablet and a preparation method thereof, the method comprises the following processes:
the ingredients are mixed according to the proportion, the prepared raw materials are added into a mixing machine, the rotating speed is set to be 100-300 r/min, the stirring is carried out for 35 min, after the raw materials are uniformly mixed, the dry tabletting is carried out, the food-grade coating agent is polyethylene glycol for coating, the vacuum microwave sterilization is carried out, and after the detection is qualified, the packaging is carried out, thus obtaining the bamboo leaf flavonoid tabletting 4.
Taking the bamboo leaf flavone tablets 1-4 prepared in the above embodiments and the existing bamboo leaf flavone tablets as a reference, adding into a rotary basket, dropping into a container, immediately starting timing, respectively sucking appropriate amount of solution at specified sampling points when 1, 5, 15, 30 and 45 minutes, immediately filtering through a 0.45 μm microporous membrane, and completing the filtration within 60 seconds from sampling to filtering. The filtrate was taken and absorbance was measured at 425nm by UV-visible spectrophotometry, the measurement results are shown in Table 1 below:
TABLE 1 dissolution test of bamboo leaf flavone tablets
Figure BDA0002488873200000071
The tests show that compared with the existing bamboo leaf flavone tablet control product, the bamboo leaf flavone tablet prepared by the formula has the advantages of fast dissolution of the effective ingredients of the bamboo leaf flavone, high bioavailability and better play of the pharmacological effects of the effective ingredients of the bamboo leaf flavone. The invention has the functions of preventing cardiovascular and cerebrovascular diseases, regulating blood fat, reducing blood viscosity, preventing hypertension, protecting liver and gallbladder, enhancing immunity and the like. Especially has the best effects of reducing blood fat and improving the immunity of the organism.
The present invention has been disclosed in terms of the preferred embodiment, but it is not intended to be limited to the embodiment, and all technical solutions obtained by substituting or converting the equivalent embodiments fall within the scope of the present invention.

Claims (9)

1. The preparation method of the bamboo leaf flavone tablet is characterized by comprising the following raw materials in parts by mass: 10-30 parts of bamboo leaf flavone, 5-20 parts of corn peptide, 5-20 parts of thickening agent, 5-15 parts of sweetening agent, 5-15 parts of soybean lecithin, 0.5-3 parts of food preservative and 0.5-3 parts of glidant auxiliary material. The preferable scheme is that the composition comprises 15-25 parts of bamboo leaf flavone, 10-15 parts of corn peptide, 10-15 parts of thickening agent, 8-12 parts of sweetening agent, 8-12 parts of soybean lecithin, 1-2 parts of food preservative and 1-2 parts of glidant auxiliary materials.
2. The method for preparing the bamboo leaf flavonoid tablet as claimed in claim 1, wherein the preparation method comprises the steps of proportioning according to the proportion of claim 1, adding the prepared raw materials into a mixer, setting the rotation speed at 100-300 rpm, stirring for 20-40 minutes, performing dry tabletting and coating after uniformly mixing, performing vacuum microwave sterilization, and packaging after qualified detection.
3. The method for preparing the bamboo leaf flavonoid tablet according to claim 1, wherein the bamboo leaf flavonoid is extracted from the raw material of the bamboo leaves by ethanol, and reaches the new resource food standard approved by the national ministry of health.
4. The method for preparing the bamboo leaf flavonoid tablet as claimed in claim 1, wherein the corn peptide is corn oligopeptide powder, which meets the new resource food standard approved by the national ministry of health.
5. The method for preparing the bamboo leaf flavonoid tablet according to claim 1, wherein the thickening agent is one or more of maltodextrin, microcrystalline cellulose, corn starch and sodium carboxymethyl cellulose.
6. The method for preparing the bamboo leaf flavonoid tablet according to claim 1, wherein the sweetener is one or more of xylo-oligosaccharide, xylitol, maltitol, stevioside and trehalose.
7. The method for preparing the bamboo leaf flavonoid tablet according to claim 1, wherein the food preservative is one or more of citric acid, sodium D-isoascorbate, malic acid and lactic acid.
8. The method for preparing the bamboo leaf flavonoid tablet according to claim 1, wherein the glidant auxiliary materials are one or more of magnesium stearate, micro-powder silica gel and talcum powder.
9. The method for preparing the bamboo leaf flavonoid tablet according to claim 1, wherein the food-grade coating agent is one or two of polyethylene glycol or hydroxypropyl methylcellulose.
CN202010399493.6A 2020-05-12 2020-05-12 Bamboo leaf flavone tablet and preparation method thereof Pending CN111418844A (en)

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Application publication date: 20200717