CN111381063B - In-vitro diagnosis analyzer and multiplexing method of sample rack thereof - Google Patents
In-vitro diagnosis analyzer and multiplexing method of sample rack thereof Download PDFInfo
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- 238000000338 in vitro Methods 0.000 title claims abstract description 61
- 238000000034 method Methods 0.000 title claims abstract description 36
- 238000003745 diagnosis Methods 0.000 title claims abstract description 9
- 238000012360 testing method Methods 0.000 claims abstract description 376
- 238000003908 quality control method Methods 0.000 claims abstract description 80
- 238000013102 re-test Methods 0.000 claims abstract description 16
- 230000003993 interaction Effects 0.000 claims description 32
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- 239000013062 quality control Sample Substances 0.000 description 3
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- 238000010586 diagram Methods 0.000 description 2
- 238000003018 immunoassay Methods 0.000 description 2
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- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
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Abstract
According to the in-vitro diagnosis analyzer and the multiplexing method of the sample rack, the target sample rack is determined according to the sample rack information input by a user on a preset display interface; modifying the type of the target sample rack in a system of an in vitro diagnostic analyzer; the sample rack is in a conventional rack, a quality control rack, a calibration rack, an emergency treatment rack or a retest rack, and the type of the sample rack corresponds to the test type; scanning a target sample rack entering the in-vitro diagnostic analyzer to obtain a scanning result; and obtaining the type of the target sample rack according to the scanning result, and testing the corresponding test type according to the type of the target sample rack. It can be seen that the present invention enables multiplexing of sample holders by modifying the type of sample holder.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to an in-vitro diagnosis analyzer and a multiplexing method of a sample rack thereof.
Background
For in-vitro diagnostic analyzers with large test throughput, sample introduction by a sample holder is an indispensable ring. Within the industry, sample holders are typically identical in structure, but differ in color, barcode type.
For example, a sample rack of a particular color can only be used for a particular type of test, such as a conventional rack can only be used for conventional tests, and cannot be used for emergency or calibration tests.
The advantages of this approach are: the sample racks are distinguished in color, so that a user can clearly select the sample rack for each test type, and confusion in use of the sample rack is avoided.
Disadvantages: the number of the sample rack configurations is fixed, and if a user needs to intensively perform a certain type of test in a period of time, the problem of insufficient sample racks can occur. For example, the manufacturer only has 3 calibration frames, each calibration frame can only apply for the calibration of 3 items, so when the user needs to perform the calibration of more than 9 items at the same time, the user can only perform the test in batches, and the operation is relatively complex and time-consuming.
The problem can be solved by adjusting the proportion of each sample rack and increasing the total number, but the cost of the user is increased for a while, and the scene requirements of all users cannot be met.
Disclosure of Invention
The invention mainly provides an in-vitro diagnosis analyzer and a multiplexing method of a sample rack thereof, and aims to realize multiplexing of the sample rack.
An embodiment provides a multiplexing method of a sample rack, including the following steps:
Determining a target sample rack according to input sample rack information on a preset display interface;
modifying the type of the target sample rack in a system of an in vitro diagnostic analyzer; the sample rack is in a conventional rack, a quality control rack, a calibration rack, an emergency treatment rack or a retest rack, and the type of the sample rack corresponds to the test type;
scanning a target sample rack entering the in-vitro diagnostic analyzer to obtain a scanning result;
and obtaining the type of the target sample rack according to the scanning result, and testing the corresponding test type according to the type of the target sample rack.
In one embodiment, the target sample holder is a conventional holder, and the modifying the type of the target sample holder in the system of the in vitro diagnostic analyzer includes: the conventional rack is designated as a quality control rack or a calibration rack.
In an embodiment, the obtaining the type of the target sample rack according to the scan result, and performing the test of the corresponding test type according to the type of the target sample rack includes:
if the type of the target sample rack is identified as a calibration rack or a quality control rack according to the scanning result, but calibration or quality control test is not required to be executed, the type of the target sample rack is identified as a conventional rack;
If the type of the target sample rack is identified as a calibration rack or a quality control rack according to the scanning result, and calibration or quality control test of a preset item needs to be executed at a preset position of the target sample rack, the type of the target sample rack is identified as the calibration rack or the quality control rack;
and correspondingly testing the sample on the target sample rack according to the type.
In an embodiment, the sample rack information includes a sample rack selection signal or a sample rack number; the step of determining the target sample rack according to the input sample rack information comprises the following steps:
and receiving a selection signal or an input sample rack number for selecting the sample rack, and determining a selected target sample rack according to the selection signal or the sample rack number.
In one embodiment, the step of modifying the type of the target specimen rack in an in vitro diagnostic analyzer system comprises:
and receiving a selection signal for selecting the target type, determining the selected target type according to the selection signal, and modifying the type of the target sample rack into the target type.
In an embodiment, after obtaining the type of the target sample rack according to the scanning result, the method further includes:
and marking the target sample rack as a first mark corresponding to the target type on a sample rack display interface.
In an embodiment, the preset display interface includes a test type application interface; the step of modifying the type of the target specimen rack in an in vitro diagnostic analyzer system comprises:
modifying the type of the target sample rack to a type corresponding to a test type application; the test type is a conventional test, a quality control test, a calibration test, an emergency test or a retest.
In one embodiment, the sample rack information includes: sample rack selection signals or sample rack numbers, sample bit selection signals or sample bits, test item selection signals or test item codes; the step of determining the target sample rack according to the input sample rack information comprises the following steps:
receiving a selection signal or an input sample rack number for selecting a sample rack, and determining the number of a selected target sample rack according to the selection signal or the sample rack number;
receiving a selection signal or an input sample position for selecting a sample position, and determining a target sample position of a sample used as a test on a target sample rack according to the selection signal or the sample position;
and receiving a selection signal for selecting the test item or an input test item code, and determining the test item of the target sample position according to the selection signal or the test item code.
In one embodiment, the scan result includes a target sample rack number and a sample bit; the step of obtaining the type of the target sample rack according to the scanning result, and the step of testing the corresponding test type according to the type of the target sample rack comprises the following steps:
obtaining target sample positions and corresponding test items of the target sample rack according to the target sample rack numbers;
judging whether the reagent required by the test item meets the preset test requirement or not;
if so, testing corresponding test items on the sample on the target sample position according to the test type corresponding to the type of the target sample rack.
In one embodiment, the test type application is a quality test application or a calibration test application; the scanning result comprises a target sample rack number and a sample position; the step of determining the target sample rack according to the input sample rack information further comprises the following steps: receiving an input request for modifying the state of the test item of the target sample position, and modifying the state of the test item of the target sample position into an application state;
the step of obtaining the type of the target sample rack according to the scanning result, and the step of testing the corresponding test type according to the type of the target sample rack comprises the following steps:
Obtaining target sample positions and corresponding test items of the target sample rack according to the target sample rack numbers;
and judging whether the state of the test item is an application state, if so, testing the corresponding test item on the sample on the target sample position according to the test type corresponding to the type of the target sample rack.
In one embodiment, the method further comprises:
after the test of the corresponding test item is completed, the number of the target sample rack, the type of the target sample rack, the target sample position and the test item are associated for use in the next test.
One embodiment provides an in vitro diagnostic analyzer comprising:
the scanning device is used for scanning the sample frame to obtain a scanning result;
the testing device is used for testing the samples in the sample rack;
the man-machine interaction device is used for receiving the input and output visual information of a user;
the processor is used for receiving input sample rack information through the human-computer interaction device on a display interface preset by the human-computer interaction device, and determining a target sample rack according to the sample rack information; modifying the type of the target sample rack in an in vitro diagnostic analyzer system; scanning a target sample rack entering the in-vitro diagnostic analyzer through a scanning device to obtain a scanning result; obtaining the type of a target sample rack according to the scanning result, and testing the corresponding test type through a testing device according to the type of the target sample rack; the sample rack is a conventional rack, a quality control rack, a calibration rack, an emergency treatment rack or a retest rack, and the type of the sample rack corresponds to the test type.
In an embodiment, the sample rack information includes a sample rack selection signal or a sample rack number; the processor determines a target sample rack according to the input sample rack information, and comprises:
and receiving a selection signal or an input sample rack number for selecting the sample rack, and determining a selected target sample rack according to the selection signal or the sample rack number.
In one embodiment, the processor modifies a type of the target specimen rack in an in vitro diagnostic analyzer system, comprising:
and receiving a selection signal for selecting the target type, determining the selected target type according to the selection signal, and modifying the type of the target sample rack into the target type.
In an embodiment, the processor is further configured to:
and after the type of the target sample rack is obtained according to the scanning result, marking the target sample rack as a first mark corresponding to the target type on a sample rack display interface of the human-computer interaction device.
In an embodiment, the preset display interface includes a test type application interface; the processor modifies a type of the target specimen rack in an in vitro diagnostic analyzer system, comprising:
modifying the type of the target sample rack to a type corresponding to a test type application; the test type is a conventional test, a quality control test, a calibration test, an emergency test or a retest.
In one embodiment, the sample rack information includes: sample rack selection signals or sample rack numbers, sample bit selection signals or sample bits, test item selection signals or test item codes; the processor determines a target sample rack from the sample rack information, comprising:
receiving a selection signal or a sample rack number for selecting a sample rack through a human-computer interaction device, and determining the number of a selected target sample rack according to the selection signal or the sample rack number;
receiving a selection signal or a sample position for selecting a sample position through a human-computer interaction device, and determining a target sample position of a sample used as a test on a target sample rack according to the selection signal or the sample position;
and receiving a selection signal or a test item code number for selecting the test item through the human-computer interaction device, and determining the test item of the target sample position according to the selection signal or the test item code number.
In one embodiment, the scan result includes a target sample rack number and a sample bit; the processor performs a test of a corresponding test type through a test device according to the type of the target sample rack, and the processor comprises:
obtaining target sample positions and corresponding test items of the target sample rack according to the target sample rack numbers;
Judging whether the reagent required by the test item meets the preset test requirement or not;
if so, testing corresponding test items on the sample on the target sample position through the testing device according to the test type corresponding to the type of the target sample rack.
In an embodiment, the test type application is a quality control test application or a calibration test application, and the scan result includes a target sample rack number and a sample position; the processor determining a target sample rack from the input sample rack information further comprises: receiving an input request for modifying the state of the test item of the target sample position through a human-computer interaction device, and modifying the state of the test item of the target sample position into an application state; the processor performs a test of a corresponding test type through a test device according to the type of the target sample rack, and the processor comprises:
obtaining target sample positions and corresponding test items of the target sample rack according to the target sample rack numbers;
judging whether the state of the test item is an application state, if so, testing the corresponding test item of the sample on the target sample position through the testing device according to the test type corresponding to the type of the target sample rack.
In one embodiment, the processor is further configured to:
after the test of the corresponding test item is completed, the number of the target sample rack, the type of the target sample rack, the target sample position and the test item are associated for use in the next test.
An embodiment provides a computer readable storage medium comprising a program executable by a processor to implement a method as described above.
According to the in-vitro diagnosis analyzer and the multiplexing method of the sample rack thereof, the target sample rack is determined according to the input sample rack information on the preset display interface; modifying the type of the target sample rack in a system of an in vitro diagnostic analyzer; the sample rack is in a conventional rack, a quality control rack, a calibration rack, an emergency treatment rack or a retest rack, and the type of the sample rack corresponds to the test type; scanning a target sample rack entering the in-vitro diagnostic analyzer to obtain a scanning result; and obtaining the type of the target sample rack according to the scanning result, and testing the corresponding test type according to the type of the target sample rack. It can be seen that the present invention enables multiplexing of sample holders by modifying the type of sample holder.
Drawings
FIG. 1 is a block diagram of an embodiment of an in vitro diagnostic analyzer according to the present invention;
FIG. 2 is a block diagram of an embodiment of an in vitro diagnostic analyzer according to the present invention;
fig. 3 is a flowchart of an embodiment of a method for multiplexing a sample rack according to the present invention.
Detailed Description
The invention will be described in further detail below with reference to the drawings by means of specific embodiments. Wherein like elements in different embodiments are numbered alike in association. In the following embodiments, numerous specific details are set forth in order to provide a better understanding of the present application. However, one skilled in the art will readily recognize that some of the features may be omitted, or replaced by other elements, materials, or methods in different situations. In some instances, some operations associated with the present application have not been shown or described in the specification to avoid obscuring the core portions of the present application, and may not be necessary for a person skilled in the art to describe in detail the relevant operations based on the description herein and the general knowledge of one skilled in the art.
Furthermore, the described features, operations, or characteristics of the description may be combined in any suitable manner in various embodiments. Also, various steps or acts in the method descriptions may be interchanged or modified in a manner apparent to those of ordinary skill in the art. Thus, the various orders in the description and drawings are for clarity of description of only certain embodiments, and are not meant to be required orders unless otherwise indicated.
The numbering of the components itself, e.g. "first", "second", etc., is used herein merely to distinguish between the described objects and does not have any sequential or technical meaning. The terms "coupled" and "connected," as used herein, are intended to encompass both direct and indirect coupling (coupling), unless otherwise indicated.
As shown in fig. 1, the in-vitro diagnostic analyzer provided by the present invention is used for analyzing an acquired sample to be tested, and includes: the device comprises a scanning device 10, a processor 20, a man-machine interaction device 30, a testing device 40 and a memory 50.
The scanning device 10 is used for scanning a sample rack entering an in-vitro diagnostic analyzer and a test tube carried by the sample rack to obtain a scanning result. Samples are typically placed in test tubes, which are often inconvenient to transport directly, so that a sample rack is required for carrying the samples, i.e. transport of the samples is effected by the sample rack. Each sample rack has an identity. The scan result includes an identification of the sample rack, such as a sample rack number. Typically a sample rack may carry a plurality of samples, i.e. the sample rack has a plurality of sample positions. The scan results may also include individual sample positions on the sample rack. The sample frame is provided with a two-dimensional code, a bar code or a radio frequency label and the like, and a scanning result is obtained by scanning the sample frame, so that the sample frame and the sample position thereof can be identified.
Referring to fig. 2, the testing device 40 is configured to test the sample in the sample rack a and output a detection result, for example, to the processor 20 or stored in the memory 50. In the embodiment of the present invention, the testing device 40 may be used for performing an immunoassay to detect an antigen and an antibody in a sample, and the corresponding in vitro diagnostic analyzer is an immunoassay analyzer; the biochemical analysis can also be carried out, various substance components in the sample can be detected, and the corresponding in-vitro diagnostic analyzer is a biochemical analyzer. Depending on the purpose of the analysis, the components of the test device 40 and the detection process may vary, and for example, a biochemical analyzer, the test device 40 generally includes a sampling mechanism (or referred to as a sample dispensing mechanism) 420, a reagent tray 430, a reaction tray 440, a measuring device 410, and a reagent collecting mechanism (or referred to as a reagent dispensing mechanism) 460. A test rail 450 is typically provided at the front end (i.e., near the side of the operator) or the rear end (i.e., the back of the instrument) of the test device 40, a sample sucking position 451 is designed on the test rail 450, and the sampling mechanism 420 is used to suck the sample to be tested from the sample rack a located at the sample sucking position 451 and add the sucked sample to the reaction container 441 placed in the reaction tray 440. The reagent collection mechanism 460 is used to draw reagent from the reagent tray 430 and add the reagent to the corresponding reaction vessel 441 such that the sample and reagent react in the reaction vessel 441. The sampling mechanism 420 and the reagent collection mechanism 460 may be different mechanisms or the same mechanism. The measurement device 410 is used to measure the reacted sample, thereby obtaining a detection result. In other embodiments, the testing device 40 may also be a chemiluminescent instrument, which also includes a magnetic separation disc, although this is not repeated.
The memory 50 is used to hold various test data, analysis results, and/or programs.
The man-machine interaction device 30 is used as an interaction interface between the analyzer and the user, and is used for receiving information input by the user and outputting the information in an acoustic, optical or electrical mode. For example, a touch screen may be used, which is capable of receiving an instruction input by a user and displaying visual information; a mouse, a keyboard, a track ball, a joystick, etc. may be used as an input device of the man-machine interaction device 30 to receive an instruction input by a user, and a display may be used as a display device of the man-machine interaction device 30 to display visual information. The display displays the analysis result and/or prompt information obtained by the processor 20 or information such as detection progress to the user in a visual mode.
The processor 20 is configured to receive, at a display interface preset by the man-machine interaction device 30, sample frame information input by a user through the man-machine interaction device 30, and determine a target sample frame according to the sample frame information; modifying the type of the target sample rack in the in vitro diagnostic analyzer; scanning a target sample rack entering the in-vitro diagnostic analyzer through a scanning device 10 to obtain a scanning result; the type of the target sample rack is obtained according to the scanning result, and the test of the corresponding test type is performed by the test device 40 according to the type of the target sample rack. The sample rack is of a conventional rack, a quality control rack, a calibration rack, an emergency treatment rack or a retest rack, and the type of the sample rack corresponds to the test type. For example, the types of tests supported by in vitro diagnostic analyzers are: the five types of conventional testing, quality control testing, calibration testing, emergency testing and retesting are adopted, and the corresponding sample frames are also five types: a conventional rack for conventional testing, a quality control rack for quality control testing, a calibration rack for calibration testing, an emergency rack for emergency testing, and a retest rack for retesting.
In the embodiment of the present invention, a number of a conventional rack, for example, N0001, may be input into the calibration test interface, the conventional rack is set as a calibration rack, and then some sample bits of the sample rack N001 are designated for a specific calibration test item, for example, positions 1-3 (sample bits) of N0001 are set as CA153 calibration test positions, so that the conventional rack N0001 can be used as a calibration test. After the sample frame N0001 is automatically sampled, the number of the sample frame is N0001, and the sample on the sample frame applies for the CA153 calibration test, the software can identify the sample frame N0001 as the calibration frame, and execute the corresponding calibration test. Therefore, the method can realize the multiplexing of different types of sample frames by modifying the attributes of the sample frames when the number of the sample frames of certain types is insufficient, can save the cost of purchasing the sample frames for users, and provides convenience for the users.
Further, the processor 20 is further configured to associate the identity of the target sample rack with the type of the target sample rack after the test of the corresponding test type is completed, so that the binding of the target sample rack and the modified type is completed, and only one type of sample rack can be tested corresponding to the type, for example, the quality control rack can only be used for performing the quality control test, and when the next test is performed, the corresponding test is directly performed with the new type, so that the user does not need to repeatedly set the sample rack, and the operation is convenient; for example, when the conventional rack N0001 is set as the calibration rack and the positions 1 to 3 are set as the CA153 calibration tests, after the test of the CA153 calibration project is performed by using the sample rack N0001, the sample rack N0001 can be used as the calibration test next time, and the positions 1 to 3 of the sample rack can still be used as the corresponding calibration test without repeated setting. If the test of the corresponding test type is not completed, the identity of the target sample rack is not related to the type of the target sample rack, and the corresponding test is still carried out in the original type when the next test is carried out, in other words, if the test of the corresponding test type is not completed, the type of the target sample rack is restored to the type before modification, and the type modification fails; for example, the normal rack N0001 is set as a calibration rack, and when the sample rack N0001 is scanned, the test type corresponding to the sample rack should be a calibration test, but the sample of the sample rack does not apply for the calibration test, the sample rack N0001 is still considered as the normal rack, not the calibration rack. Of course, after the sample rack type is successfully modified, the sample rack type can be restored to the type before modification according to the instruction of a user.
In a specific embodiment, the preset display interface is a setting interface, and the user sets the target sample rack of the type to be modified in the setting interface. For example, the setup interface displays a plurality of sample rack numbers. The sample rack information includes a sample rack selection signal, and the processor 20 receives the selection signal for selecting a sample rack through the man-machine interaction device 30, and determines a target sample rack selected by a user according to the selection signal. For another example, the sample rack information includes a sample rack number; the processor 20 receives the sample rack number input by the user through the man-machine interaction device 30, and determines the target sample rack selected by the user according to the sample rack number. In this embodiment, the identity of the sample rack is a sample rack number, that is, the user may determine, by selecting or inputting, the sample rack (target sample rack) of the type that needs to be modified.
After determining the target sample rack, the processor 20 receives a selection signal for selecting a target type through the man-machine interaction device 30, determines the target type selected by the user according to the selection signal, and modifies the type of the target sample rack to the target type, thereby associating the target sample rack number with the target type.
After a user determines a target sample rack of a type to be modified in a system of the analyzer, placing a sample in the target sample rack, and placing the target sample rack in a sample injection area of the analyzer. After the sample is introduced into the target sample rack, the scanning device 10 scans the target sample rack entering the in-vitro diagnostic analyzer to obtain the number of the target sample rack. The processor 20 obtains the type of the target sample rack according to the number of the target sample rack, tests the corresponding test type according to the type of the target sample rack, and marks the target sample rack as a first mark corresponding to the target type on the sample rack display interface of the man-machine interaction device 30 so as to prompt the user. The first mark is used for marking the type of the sample rack on the display interface, and can be a color mark, a graphic mark or a mark combining colors and graphics. Taking the example that the first mark of the conventional sample rack is medium gray, the first mark of the quality control sample rack is lake blue, the first mark of the calibration sample rack is orange, the first mark of the emergency sample rack is red, and the first mark of the retest sample rack is dark blue, if the user modifies the conventional sample rack into the quality control sample rack, the first mark seen on the sample display interface is lake blue after the scanning device 10 scans the target sample rack, so that the current type of the sample rack is marked and is distinguished from other types of sample racks, and the user can conveniently view various types of sample racks according to color classification.
In one embodiment, the preset display interface includes a test type application interface; the processor 20 modifies the type of target sample rack in the in vitro diagnostic analyzer system, including: modifying the type of the target sample rack into a type corresponding to the test type application; the test type is a conventional test, a quality control test, a calibration test, an emergency test or a retest. For example, during the quality control test, the user can input the sample rack information of a conventional sample rack on the quality control test application interface, and the processor 20 can automatically modify the conventional sample rack into the quality control sample rack, so that the multiplexing of the sample rack is realized, and the operation is simple and efficient.
In this embodiment, the sample rack information includes: a sample rack selection signal or sample rack number, a sample bit selection signal or sample bit, a test item (e.g., tg-1, tg, CEA, E3, CA153, etc.) selection signal or test item code. The processor 20 receives a selection signal for selecting a sample rack or an input sample rack number through the man-machine interaction device 30, and determines the number of the selected target sample rack according to the selection signal or the sample rack number; receiving a selection signal or a sample position for selecting a sample position through the man-machine interaction device 30, and determining a target sample position of a sample used as a test on a target sample rack according to the selection signal or the sample position; a selection signal or a test item code for selecting a test item is received through the man-machine interaction device 30, and the test item of the target sample position is determined according to the selection signal or the test item code.
In this embodiment, the scan result includes the target sample rack number and the sample bit; the processor 20 performs a test of a corresponding test type by the test device 40 according to the type of the target sample rack, including: obtaining target sample positions and corresponding test items of the target sample rack according to the number of the target sample rack; judging whether the reagent required by the test item meets the preset test requirement; for example, determining whether reagents required for testing items within the analyzer are present, sufficient, etc.; if so, testing corresponding test items on the sample on the target sample position through the testing device 40 according to the test type corresponding to the type of the target sample rack; otherwise, testing is carried out according to the testing type corresponding to the type before modification, namely the sample rack type is failed to be modified.
Further, when the test type application is a quality control test application or a calibration test application, the human-computer interaction device receives sample frame information input by a user at a quality control test application interface or a calibration test application interface, determines a target sample frame according to the sample frame information, and modifies the type of the target sample frame in the in-vitro diagnostic analyzer system. At the quality control test application interface or calibration test application interface of the man-machine interaction device 30, according to the request of modifying the state of the test item of the target sample position input by the user, the processor 20 modifies the state of the test item of the target sample position into the application state; scanning a target sample rack entering the in-vitro diagnostic analyzer through a scanning device 10 to obtain a target sample rack number and a sample position, obtaining the type of the target sample rack according to the target sample rack number, and obtaining the target sample position and a corresponding test item of the target sample rack according to the target sample rack number; judging whether the state of the test item is an application state, if so, testing the corresponding test item of the sample on the target sample position through the test device 40 according to the test type corresponding to the type of the target sample rack; after the quality control test of the corresponding test item is completed, displaying that the quality control test is completed on a display interface; after the calibration test of the corresponding test item is completed, switching the state of the test item into a successful state; after the test of the corresponding test item is completed, the target sample frame number, the type of the target sample frame, the target sample position and the test item are associated, the sample frame type is the modified type in the next test, and the sample frame number can be displayed on an application interface corresponding to the new type for selection by a user. If the state of the test item is not the application state, the type of the target sample rack is restored to the type before modification, the test is not performed or the test corresponding to the type before modification is performed, and the type of the sample rack is still the type before modification in the next test. The arrangement is beneficial to fool-proofing. For example, at the quality test application interface or calibration test application interface, the user determines the conventional rack numbered N0001 as the target sample rack (target sample rack is conventional rack) by inputting sample rack information, with 1-3 sample bits for calibration of CA153 (test item, the most important specific marker of breast cancer). The in vitro diagnostic analyzer designates the conventional rack N0001 as a quality control rack or a calibration rack. After N0001 automatic sample injection, the scanning device scans N0001 to obtain a scanning result, for example, the number of a sample frame is N0001, the sample position of a sample to be tested is 1-3, and the corresponding test item is CA153; obtaining the type of the target sample rack N0001 as a quality control rack or a calibration rack according to the sample rack number; if the target sample rack N0001 does not need to perform calibration or quality control test, for example, whether 1-3 sample bits of the test type application interface have the application state of CA153 is determined, if it is not stated that the target sample rack N0001 does not need to perform calibration or quality control test, the type of the target sample rack N0001 is determined to be a conventional rack, and the conventional test is performed. If the target sample position (preset position) of the target sample frame N0001 needs to execute the calibration or quality control test of a preset item, if the 1-3 sample positions of the test type application interface have the application state of CA153, the type of the target sample frame N0001 is determined to be the quality control frame or the calibration frame, and then the quality control test or the calibration test corresponding to CA153 is carried out on the samples on the 1-3 sample positions; after the test is finished, when the N0001 is used for carrying out a quality control test application or a calibration test application, the default 1-3 sample positions of the system are CA153 quality control test or calibration test, and a user does not need to repeatedly set the sample positions, so that the efficiency is improved.
Therefore, the invention realizes the multiplexing of the sample rack by modifying the type of the sample rack, and one sample rack type can only be tested in a corresponding type, thereby being beneficial to foolproof.
Based on the in-vitro diagnostic analyzer provided by the embodiment, the invention provides a method for multiplexing a sample rack, as shown in fig. 3, comprising the following steps:
step 1, determining a target sample rack on a preset display interface according to sample rack information input by a user.
Step 2, modifying the type of the target sample rack in an in-vitro diagnosis analyzer system; the sample rack is a conventional rack, a quality control rack, a calibration rack, an emergency treatment rack or a retest rack, and the type of the sample rack corresponds to the test type.
And 3, scanning the target sample rack and the test tube carried by the sample rack which enter the in-vitro diagnostic analyzer to obtain a scanning result.
And 4, obtaining the type of the target sample rack according to the scanning result, and testing the corresponding test type according to the type of the target sample rack. After the test of the corresponding test type is finished, the identity of the target sample rack is related to the type of the target sample rack, the binding of the target sample rack and the modified type is finished, one type of sample rack can only be used for testing the corresponding type, for example, the quality control rack can only be used for quality control testing, when the next test is carried out, the corresponding test is directly carried out by the new type, the user does not need to repeatedly set, and the operation is convenient; for example, when the conventional rack N0001 is set as the calibration rack and the positions 1 to 3 are set as the CA153 calibration tests, after the test of the CA153 calibration project is performed by using the sample rack N0001, the sample rack N0001 can be used as the calibration test next time, and the positions 1 to 3 of the sample rack can still be used as the corresponding calibration test without repeated setting. If the test of the corresponding test type is not completed, the identity of the target sample rack is not related to the type of the target sample rack, and the corresponding test is still carried out in the original type when the next test is carried out, in other words, if the test of the corresponding test type is not completed, the type of the target sample rack is restored to the type before modification, and the type modification fails; for example, the normal rack N0001 is set as a calibration rack, and when the sample rack N0001 is scanned, the test type corresponding to the sample rack should be a calibration test, but the sample of the sample rack does not apply for the calibration test, the sample rack N0001 is still considered as the normal rack, not the calibration rack. Of course, after the sample rack type is successfully modified, the sample rack type can be restored to the type before modification according to the instruction of a user.
In a specific embodiment, the preset display interface is a setting interface, and the user sets the target sample rack of the type to be modified in the setting interface. For example, the setup interface displays a plurality of sample rack numbers. The sample rack information includes a sample rack selection signal, a selection signal for selecting a sample rack is received, and a target sample rack selected by a user is determined based on the selection signal. For another example, the sample rack information includes a sample rack number; and receiving a sample rack number input by a user, and determining a target sample rack selected by the user according to the sample rack number. In this embodiment, the identity of the sample rack is a sample rack number, that is, the user may determine, by selecting or inputting, the sample rack (target sample rack) of the type that needs to be modified.
After the target sample rack is determined, a selection signal for selecting the target type is received, the target type selected by a user is determined according to the selection signal, and the type of the target sample rack is modified to be the target type, so that the number of the target sample rack is associated with the target type.
After a user determines a target sample rack of a type to be modified in a system of the analyzer, placing a sample in the target sample rack, and placing the target sample rack in a sample injection area of the analyzer. After the sample is introduced into the target sample rack, scanning the target sample rack entering the in-vitro diagnostic analyzer to obtain a target sample rack number; and obtaining the type of the target sample rack according to the number of the target sample rack, testing the corresponding test type according to the type of the target sample rack, and marking the target sample rack as a first mark corresponding to the target type on a sample rack display interface so as to prompt a user. The first identifier is used for identifying the type of the sample rack on the display interface.
In one embodiment, the preset display interface includes a test type application interface; step 2 comprises: modifying the type of the target sample rack into a type corresponding to the test type application; the test type is a conventional test, a quality control test, a calibration test, an emergency test or a retest. For example, in an embodiment of the present invention, a number of a conventional rack, such as N0001, may be input to the calibration test interface, the conventional rack is set as a calibration rack, and then some sample bits of the sample rack N001 are designated for a specific calibration test item, such as positions 1-3 (sample bits) of N0001 are set as CA153 calibration test positions, so that the conventional rack N0001 can be used as a calibration test. After the sample frame N0001 is automatically sampled, the number of the sample frame is N0001, and the sample on the sample frame applies for the CA153 calibration test, the software can identify the sample frame N0001 as the calibration frame, and execute the corresponding calibration test. Therefore, the method can realize the multiplexing of different types of sample frames by modifying the attributes of the sample frames when the number of the sample frames of certain types is insufficient, can save the cost of purchasing the sample frames for users, and provides convenience for the users.
In this embodiment, the sample rack information includes: sample rack select signal or sample rack number, sample bit select signal or sample bit, test item select signal or test item code number. The step 1 comprises the following steps: receiving a selection signal or an input sample rack number for selecting a sample rack, and determining the number of a selected target sample rack according to the selection signal or the sample rack number; receiving a selection signal or a sample bit for selecting a sample bit, and determining a target sample bit of a sample used for testing on a target sample rack according to the selection signal or the sample bit; and receiving a selection signal or a test item code for selecting the test item, and determining the test item of the target sample position according to the selection signal or the test item code.
In this embodiment, the scan result includes the target sample rack number and the sample bit; in step 4, testing of the corresponding test type is performed according to the type of the target sample rack, including: obtaining target sample positions and corresponding test items of the target sample rack according to the number of the target sample rack; judging whether the reagent required by the test item meets the preset test requirement; for example, determining whether reagents required for testing items within the analyzer are present, sufficient, etc.; if so, testing corresponding test items on the sample on the target sample position according to the test type corresponding to the type of the target sample rack; otherwise, testing is carried out according to the testing type corresponding to the type before modification, namely the sample rack type is failed to be modified.
Further, when the test type application is a quality control test application or a calibration test application, the sample rack information input by the user is received at the quality control test application interface or the calibration test application interface, the target sample rack is determined according to the sample rack information, and the type of the target sample rack in the in-vitro diagnosis analyzer system is modified. Modifying the state of the test item corresponding to the target sample position in the quality control test application into an application state according to a request for modifying the state of the test item of the target sample position, which is input by a user, in a quality control test application interface; in a calibration test application interface, according to a request for modifying the state of a test item of a target sample position input by a user, modifying the state of the test item corresponding to the target sample position in the calibration test application into an application state; scanning a target sample rack entering the in-vitro diagnostic analyzer to obtain a target sample rack number and a sample position, obtaining the type of the target sample rack according to the target sample rack number, and obtaining the target sample position and a corresponding test item of the target sample rack according to the target sample rack number; judging whether the state of the test item is an application state, if so, testing the corresponding test item on the sample on the target sample position according to the test type corresponding to the type of the target sample rack; after the test of the corresponding test item is completed, the target sample frame number, the type of the target sample frame, the target sample position and the test item are associated, the sample frame type is the modified type in the next test, and the sample frame number can be displayed on an application interface corresponding to the new type for selection by a user. If the state of the test item is not the application state, the type of the target sample rack is restored to the type before modification, the test is not performed or the test corresponding to the type before modification is performed, and the type of the sample rack is still the type before modification in the next test. The arrangement is beneficial to fool-proofing. For example, at the quality test application interface or calibration test application interface, the user determines the conventional rack numbered N0001 as the target sample rack (target sample rack is conventional rack) by inputting sample rack information, with 1-3 sample bits for calibration of CA153 (test item, the most important specific marker of breast cancer). The in vitro diagnostic analyzer designates the conventional rack N0001 as a quality control rack or a calibration rack. After N0001 automatic sample injection, the scanning device scans N0001 to obtain a scanning result, for example, the number of a sample frame is N0001, the sample position of a sample to be tested is 1-3, and the corresponding test item is CA153; obtaining the type of the target sample rack N0001 as a quality control rack or a calibration rack according to the sample rack number; if the target sample rack N0001 does not need to perform calibration or quality control test, for example, whether 1-3 sample bits of the test type application interface have the application state of CA153 is determined, if it is not stated that the target sample rack N0001 does not need to perform calibration or quality control test, the type of the target sample rack N0001 is determined to be a conventional rack, and the conventional test is performed. If the target sample position (preset position) of the target sample frame N0001 needs to execute the calibration or quality control test of a preset item, if the 1-3 sample positions of the test type application interface have the application state of CA153, the type of the target sample frame N0001 is determined to be the quality control frame or the calibration frame, and then the quality control test or the calibration test corresponding to CA153 is carried out on the samples on the 1-3 sample positions; after the test is finished, when the N0001 is used for carrying out a quality control test application or a calibration test application, the default 1-3 sample positions of the system are CA153 quality control test or calibration test, and a user does not need to repeatedly set the sample positions, so that the efficiency is improved.
Since the process and effects of the method are described in detail in the embodiments of the analyzer, they are not described in detail herein.
Reference is made to various exemplary embodiments herein. However, those skilled in the art will recognize that changes and modifications may be made to the exemplary embodiments without departing from the scope herein. For example, the various operational steps and components used to perform the operational steps may be implemented in different ways (e.g., one or more steps may be deleted, modified, or combined into other steps) depending on the particular application or taking into account any number of cost functions associated with the operation of the system.
Additionally, as will be appreciated by one of skill in the art, the principles herein may be reflected in a computer program product on a computer readable storage medium preloaded with computer readable program code. Any tangible, non-transitory computer readable storage medium may be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROMs, DVDs, blu-Ray disks, etc.), flash memory, and/or the like. These computer program instructions may be loaded onto a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions which execute on the computer or other programmable data processing apparatus create means for implementing the functions specified. These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including means which implement the function specified. The computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified.
While the principles herein have been shown in various embodiments, many modifications of structure, arrangement, proportions, elements, materials, and components, which are particularly adapted to specific environments and operative requirements, may be used without departing from the principles and scope of the present disclosure. The above modifications and other changes or modifications are intended to be included within the scope of this document.
The foregoing detailed description has been described with reference to various embodiments. However, those skilled in the art will recognize that various modifications and changes may be made without departing from the scope of the present disclosure. Accordingly, the present disclosure is to be considered as illustrative and not restrictive in character, and all such modifications are intended to be included within the scope thereof. Also, advantages, other advantages, and solutions to problems have been described above with regard to various embodiments. The benefits, advantages, solutions to problems, and any element(s) that may cause any benefit, advantage, or solution to occur or become more pronounced are not to be construed as a critical, required, or essential feature. The terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, system, article, or apparatus. Furthermore, the term "couple" and any other variants thereof are used herein to refer to physical connections, electrical connections, magnetic connections, optical connections, communication connections, functional connections, and/or any other connection.
Those skilled in the art will recognize that many changes may be made to the details of the above-described embodiments without departing from the underlying principles of the invention. Accordingly, the scope of the invention should be determined from the following claims.
Claims (21)
1. A method of multiplexing a sample rack, comprising the steps of:
determining a target sample rack according to input sample rack information on a preset display interface; the target sample rack is a sample rack of a type needing to be modified; the type of the sample rack in the system of the in-vitro diagnosis analyzer is a conventional rack, a quality control rack, a calibration rack, an emergency treatment rack or a retest rack, and the type of the sample rack in the system corresponds to the test type;
modifying the type of the target specimen rack in a system of an in vitro diagnostic analyzer based on the display interface; the modified type of the target sample rack is a calibration rack or a quality control rack;
scanning a target sample rack entering the in-vitro diagnostic analyzer to obtain a scanning result;
obtaining the type of the target sample rack in the system according to the scanning result;
if the type of the target sample rack in the system is identified as a calibration rack or a quality control rack according to the scanning result, and calibration or quality control test of a preset item needs to be executed at a preset position of the target sample rack, the type of the target sample rack in the system is identified as the calibration rack or the quality control rack; and executing calibration or quality control test of a preset item on the sample at the preset position of the target sample rack.
2. The method of claim 1, wherein the target sample rack is a conventional rack, and wherein modifying the type of the target sample rack in a system of an in vitro diagnostic analyzer based on the display interface comprises: and designating the conventional rack as a calibration rack or a quality control rack based on the display interface.
3. The method as recited in claim 2, further comprising:
if the type of the target sample rack in the system is identified as a calibration rack or a quality control rack according to the scanning result, but calibration or quality control test is not required to be executed, the type of the target sample rack in the system is identified as a conventional rack; no testing or conventional testing of the samples on the target sample rack is performed depending on the type of identification.
4. The method of claim 1, wherein the sample rack information comprises a sample rack selection signal or a sample rack number; the step of determining the target sample rack according to the input sample rack information comprises the following steps:
and receiving a selection signal or an input sample rack number for selecting the sample rack, and determining a selected target sample rack according to the selection signal or the sample rack number.
5. The method of claim 4, wherein the step of modifying the type of the target specimen rack in an in vitro diagnostic analyzer system based on the display interface comprises:
And receiving a selection signal for selecting a target type based on the display interface, determining the selected target type according to the selection signal, and modifying the type of the target sample rack in the system into the target type.
6. The method of claim 1 or 5, further comprising, after deriving the type of target specimen rack in the system from the scan result:
and marking the target sample rack as a first mark corresponding to the target type on a sample rack display interface.
7. The method of claim 1, wherein the predetermined display interface comprises a test type application interface; the step of modifying the type of the target specimen rack in an in vitro diagnostic analyzer system based on the display interface comprises:
based on the test type application interface, modifying the type of the target sample rack in the system into a type corresponding to a test type application; the test type is a conventional test, a quality control test, a calibration test, an emergency test or a retest.
8. The method of claim 7, wherein the sample rack information comprises: sample rack selection signals or sample rack numbers, sample bit selection signals or sample bits, test item selection signals or test item codes; the step of determining the target sample rack according to the input sample rack information comprises the following steps:
Receiving a selection signal or an input sample rack number for selecting a sample rack, and determining the number of a selected target sample rack according to the selection signal or the sample rack number;
receiving a selection signal or an input sample position for selecting a sample position, and determining a target sample position of a sample used as a test on a target sample rack according to the selection signal or the sample position;
and receiving a selection signal for selecting the test item or an input test item code, and determining the test item of the target sample position according to the selection signal or the test item code.
9. The method of claim 8, wherein the scan result includes a target sample rack number and a sample bit; the performing calibration or quality control test of a preset item on a sample at a preset position of the target sample rack includes:
obtaining target sample positions and corresponding test items of the target sample rack according to the target sample rack numbers;
judging whether the reagent required by the test item meets the preset test requirement or not;
if yes, performing calibration or quality control test of the corresponding test item on the sample on the target sample position of the target sample rack.
10. The method of claim 8, wherein the test type application is a calibration test application or a quality test application; the scanning result comprises a target sample rack number and a sample position; the step of determining the target sample rack according to the input sample rack information further comprises the following steps: receiving an input request for modifying the state of the test item of the target sample position, and modifying the state of the test item of the target sample position into an application state;
The performing calibration or quality control test of a preset item on a sample at a preset position of the target sample rack includes:
obtaining target sample positions and corresponding test items of the target sample rack according to the target sample rack numbers;
and judging whether the state of the test item is an application state, if so, performing calibration or quality control test of the corresponding test item on the sample on the target sample position of the target sample rack.
11. The method of claim 9 or 10, further comprising:
and after the test of the corresponding test item is completed, the number of the target sample rack, the type of the target sample rack in the system, the target sample position and the test item are associated for use in the next test.
12. An in vitro diagnostic analyzer comprising:
the scanning device is used for scanning the sample frame to obtain a scanning result;
the testing device is used for testing the samples in the sample rack;
the man-machine interaction device is used for receiving the input and output visual information of a user;
the processor is used for receiving input sample rack information through the human-computer interaction device on a display interface preset by the human-computer interaction device, and determining a target sample rack according to the sample rack information; the target sample rack is a sample rack of a type needing to be modified; modifying the type of the target specimen rack in an in vitro diagnostic analyzer system based on the display interface; the modified type of the target sample rack is a calibration rack or a quality control rack; scanning a target sample rack entering the in-vitro diagnostic analyzer through a scanning device to obtain a scanning result; obtaining the type of the target sample rack in the system according to the scanning result; if the type of the target sample rack in the system is identified as a calibration rack or a quality control rack according to the scanning result, and calibration or quality control test of a preset item needs to be executed at a preset position of the target sample rack, the type of the target sample rack in the system is identified as the calibration rack or the quality control rack; performing calibration or quality control test of a preset item on a sample at a preset position of the target sample rack through a testing device; the sample rack in the system is of a conventional rack, a quality control rack, a calibration rack, an emergency treatment rack or a retest rack, and the sample rack in the system corresponds to the test type.
13. The in vitro diagnostic analyzer of claim 12 wherein said sample rack information comprises a sample rack selection signal or a sample rack number; the processor determines a target sample rack according to the input sample rack information, and comprises:
and receiving a selection signal or an input sample rack number for selecting the sample rack, and determining a selected target sample rack according to the selection signal or the sample rack number.
14. The in-vitro diagnostic analyzer of claim 12 wherein the processor modifies a type of the target specimen rack in an in-vitro diagnostic analyzer system based on the display interface, comprising:
and receiving a selection signal for selecting a target type based on the display interface, determining the selected target type according to the selection signal, and modifying the type of the target sample rack in the system into the target type.
15. The in vitro diagnostic analyzer of claim 12 wherein said processor is further configured to:
and after the type of the target sample rack in the system is obtained according to the scanning result, marking the target sample rack as a first mark corresponding to the target type on a sample rack display interface of the human-computer interaction device.
16. The in-vitro diagnostic analyzer of claim 12 wherein said preset display interface comprises a test type application interface; the processor modifies a type of the target specimen rack in an in vitro diagnostic analyzer system based on the display interface, comprising:
based on the test type application interface, modifying the type of the target sample rack in the system into a type corresponding to a test type application; the test type is a conventional test, a quality control test, a calibration test, an emergency test or a retest.
17. The in vitro diagnostic analyzer of claim 16 wherein said sample rack information comprises: sample rack selection signals or sample rack numbers, sample bit selection signals or sample bits, test item selection signals or test item codes; the processor determines a target sample rack from the sample rack information, comprising:
receiving a selection signal or a sample rack number for selecting a sample rack through a human-computer interaction device, and determining the number of a selected target sample rack according to the selection signal or the sample rack number;
receiving a selection signal or a sample position for selecting a sample position through a human-computer interaction device, and determining a target sample position of a sample used as a test on a target sample rack according to the selection signal or the sample position;
And receiving a selection signal or a test item code number for selecting the test item through the human-computer interaction device, and determining the test item of the target sample position according to the selection signal or the test item code number.
18. The in vitro diagnostic analyzer of claim 17 wherein said scan results comprise a target sample rack number and sample bits; the processor performs calibration or quality control testing of a preset item on a sample at a preset position of the target sample rack through a testing device, and the calibration or quality control testing comprises the following steps:
obtaining target sample positions and corresponding test items of the target sample rack according to the target sample rack numbers;
judging whether the reagent required by the test item meets the preset test requirement or not;
if yes, the test device is used for carrying out calibration or quality control test on the sample on the target sample position of the target sample rack.
19. The in vitro diagnostic analyzer of claim 17 wherein said test type application is a calibration test application or a mass control test application, said scan results including a target sample rack number and sample position; the processor determining a target sample rack from the input sample rack information further comprises: receiving an input request for modifying the state of the test item of the target sample position through a human-computer interaction device, and modifying the state of the test item of the target sample position into an application state; the processor performs calibration or quality control testing of a preset item on a sample at a preset position of the target sample rack through a testing device, and the calibration or quality control testing comprises the following steps:
Obtaining target sample positions and corresponding test items of the target sample rack according to the target sample rack numbers;
and judging whether the state of the test item is an application state, if so, performing calibration or quality control test of the corresponding test item on the sample on the target sample position of the target sample rack through the test device.
20. The in vitro diagnostic analyzer of claim 18 or 19 wherein the processor is further configured to:
and after the test of the corresponding test item is completed, the number of the target sample rack, the type of the target sample rack in the system, the target sample position and the test item are associated for use in the next test.
21. A computer readable storage medium comprising a program executable by a processor to implement the method of any one of claims 1-11.
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