CN111345309A - Insecticidal and bactericidal composition, preparation and application thereof - Google Patents
Insecticidal and bactericidal composition, preparation and application thereof Download PDFInfo
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- CN111345309A CN111345309A CN201811562040.XA CN201811562040A CN111345309A CN 111345309 A CN111345309 A CN 111345309A CN 201811562040 A CN201811562040 A CN 201811562040A CN 111345309 A CN111345309 A CN 111345309A
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- insecticidal
- tiadinil
- bactericidal
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- guadipyr
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
Abstract
The invention relates to the technical field of pesticides, and particularly relates to an insecticidal and bactericidal composition, a preparation and application thereof. The active ingredients of the composition are guadipyr and tiadinil, and the two active ingredients are reasonably compounded, so that the composition can treat insect pests and diseases at the same time, and has an obvious synergistic effect. The medicine has less times of administration, multiple action targets and low resistance risk. In addition, the environment-friendly insecticidal and bactericidal composition has good environmental compatibility, low use cost and good control effect.
Description
Technical Field
The invention relates to the technical field of pesticides, and particularly relates to an insecticidal and bactericidal composition, a preparation and application thereof.
Background
The crops such as fruit trees, rice, vegetables and the like in China suffer serious losses due to diseases and insect pests every year, and the use of the insecticidal bactericide for preventing and treating the diseases and insect pests has important significance for protecting the normal growth of the crops. Especially in situations where fungi and/or pests are susceptible to mixing or where resistance to currently known products has developed or is at risk of developing resistance, there is a greater need to find a more effective method of control or prevention. The most easily-generated problem of preventing and treating the diseases and insect pests is the generation of drug resistance, secondly, most importantly, the prevention and treatment functions are multiple, the prevention and treatment effect is excellent, however, the existing pesticides are single, in the aspect of preventing and treating the diseases and insect pests, farmers need to take medicaments for multiple times to respectively prevent and treat different diseases and insect pests, the labor force is increased, the medicament cost is increased, the effect of preventing and treating the diseases every time is not comprehensive and ideal enough, the using amount is large every time, the pesticides are frequently taken, the pollution to the environment is large, the pesticide residue of crops is large, and the human health is not facilitated.
For example, CN 105613520B discloses a bactericidal composition containing tiadinil, which contains an active ingredient a and an active ingredient B, wherein the active ingredient a is selected from tiadinil, and the active ingredient B is selected from any one of the following compounds: dimethomorph, metalaxyl and salt, propamocarb and salt, cymoxanil. The invention can only control diseases and has no effect on insect pests
CN104872167A, CN103444763B, CN104824011B and CN102792964B disclose pesticide compositions containing guadipyr, which can only control pests and have no effect on diseases.
CN101087531B discloses an insecticide based on selected neonicotinoids and strobilurins, which is compounded by neonicotinoids (one selected from clothianidin, imidacloprid, thiacloprid, dinotefuran, acetamiprid, nitenpyram and thiamethoxam) and at least one selected from strobilurin fungicides (picoxystrobin, pyraclostrobin, dimoxystrobin, metominostrobin and orysastrobin). Wherein the neonicotinoid insecticide component threatens the survival of pollinating insects such as bees and the like, and is not beneficial to ecological environmental protection.
CN103141500B discloses an insecticidal and bactericidal composition containing tiadinil, which comprises two active ingredients of an effective amount of a component A and a component B, wherein the component A is tiadinil, and the component B is selected from one of nicotine insecticidal ingredients of nitenpyram, thiamethoxam, acetamiprid, thiacloprid, dinotefuran and clothianidin. Wherein the neonicotinoid insecticide component threatens the survival of pollinating insects such as bees and the like, and is not beneficial to ecological environmental protection.
Neonicotinoid insecticides are the insecticides which grow the fastest in the world agricultural chemical market in recent years, live at the first of various insecticide markets, the environmental problems brought by the neonicotinoid insecticides are more and more concerned by people, such as the problems of easy generation of resistance and phytotoxicity after long-term use, and high toxicity to bees, and more evidences show that neonicotinoid insecticides threaten the survival of pollinating insects such as bees and lead to the reduction of bee habitats and population quantity, all countries in the world pay high attention, and some countries adopt forbidden measures, such as: in 8 months 2012, the department of french agriculture banned the use of thiamethoxam for the treatment of oilseed rape seed and called for the complete ban of thiamethoxam within the european union; three neonicotinoid insecticides imidacloprid, thiamethoxam and clothianidin are temporarily forbidden in European Union beginning 12 months in 2013; against the potential risk of neonicotinoid pesticides to bees, countries in the united states, canada, brazil, etc. have begun to follow up with the examination of neonicotinoid insecticides; the ministry of agriculture in China also organizes the risk analysis workshop of neonicotinoid insecticides on bees in China, emphasizing that the influence on bees is more concerned in the product registration review. Therefore, the development of low-toxicity alternative insecticide varieties safe to bees is a development trend at home and abroad, and has great ecological and environmental protection significance.
The guadipyr has the chemical name of 1-nitro-3- [ (6-chloropyridine-3-yl) methyl ] -4-pentamethylene aminoguanidine, belongs to a nitro aminoguanidine compound, is a high-efficiency, low-toxicity and low-residue all-new pesticide, constructs the active structures of a neonicotinoid pesticide and a semicarbazone pesticide into the same molecule, and has the structural characteristics of the neonicotinoid pesticide and a sodium ion channel inhibitor pesticide, so that the insecticidal spectrum of the two pesticides is combined, the application range is wide, the insecticidal spectrum has the characteristic of multiple action targets, and the speed of generating the drug resistance of pests is greatly reduced. The product has good control effect on various pests such as aphids, plant hoppers, cotton bollworms and the like. The guadipyr has a unique action mechanism, so that the guadipyr has an obvious control effect and a longer lasting period compared with a neonicotinoid insecticide, has low toxicity to beneficial organisms such as bees, is 10800mg/L and 51.82 mu g/bee respectively for LC50 of acute ingestion (48h) and acute contact killing (48h) of the bees, is far lower than the neonicotinoid insecticide (for example, imidacloprid is 11.99mg/L and 0.0723 mu g/bee respectively), and overcomes the disadvantage of biotoxicity of the neonicotinoid insecticide.
Tiadinil (tiadinil), the chemical name of which is 3 '-chloro-4, 4' -dimethyl-1, 2, 3-thiadiazole-5-formanilide, is a novel thiadiazole formamide bactericide, and the effect of the tiadinil is mainly used for preventing pathogenic bacteria hyphae from invading adjacent healthy cells and inducing the generation of disease-resistant genes. Can interfere germination and infection of pathogenic bacteria hyphae, can activate the disease resistance function of crops, is suitable for water management, has long lasting period and good safety, and has better control effect on the pyricularia grisea and the pyricularia paniculata. In addition, tiadinil also has certain effects on powdery mildew, rust disease, late blight or epidemic disease, downy mildew and the like. The recommended dosage is safe to various crops, low in toxicity to mammals and safe to the environment. But tiadinil alone is costly and risks drug resistance.
Although a great number of preparations are available in the prior art, which combine insecticides and bactericides, the use of the combination of the pentaerythrina and tiadinil has not been reported.
Disclosure of Invention
In view of the above, the invention provides an insecticidal and bactericidal composition with good insecticidal and bactericidal effects, less drug use times and low resistance risk, a preparation and use thereof.
The invention provides an insecticidal and bactericidal composition which comprises guadipyr and tiadinil.
The guadipyr belongs to a nitroaminoguanidine compound, is a high-efficiency, low-toxicity and low-residue all-new pesticide, has the structural characteristics of both the neonicotinoid pesticide and the sodium ion channel inhibitor pesticide, has the insecticidal spectrum of the two pesticides, has a wide application range, has the characteristic of multiple action targets, and can greatly reduce the speed of the drug resistance of pests. Low toxicity to beneficial organisms such as bees.
The tiadinil and the thiadiazole carboxamide novel bactericide has the action mechanism of mainly preventing pathogenic bacteria hypha from invading adjacent healthy cells and can induce to generate disease-resistant genes. Can interfere the germination and infection of pathogenic bacteria hypha and activate the disease resistance of crops, has long lasting period and good safety, is safe to various crops under recommended dosage, has low toxicity to mammals and is safe to the environment.
The two effective components, namely the guadipyr and the tiadinil, have different action mechanisms and are compounded, and the embodiment of the invention shows that the pesticide composition has certain complementary action and synergistic action in a reasonable range, can reduce the use amount of pesticide active ingredients and improve the control effect. The mass ratio of the guadipyr to the tiadinil is 1: 100-50: 1, preferably 1: 40-10: 1, and more preferably 1: 10-1: 1.
The invention also provides application of the composition in preventing and treating crop diseases and insect pests. Preferably, the crops are rice, wheat, vegetables, bananas, watermelons, corns, peanuts, rapes, fruit trees and ornamental plants. Wherein the vegetables include cucumber, cabbage, beans, potato, tomato, etc.
The insect pests are rice planthopper, stem borer, leafhopper, aphid and noctuid; the diseases comprise rice blast, wheat powdery mildew, cucumber downy mildew and potato late blight.
The invention also provides an insecticidal and bactericidal preparation which comprises the insecticidal and bactericidal composition and auxiliary materials acceptable in pesticide preparations.
The insecticidal and bactericidal composition is preferably 1-80% by mass, and more preferably 5-50% by mass.
A person skilled in the art can prepare any agriculturally acceptable dosage form by selecting auxiliary materials according to a method known in the art, and the preferred dosage form is wettable powder, suspending agent, water dispersible granules, dry powder, suspoemulsion, suspended seed coating agent and seed treatment dispersible powder.
The adjuvant may be one well known to those skilled in the art and suitable for use in pesticide formulations, and the present invention preferably includes one or a mixture of two or more of a dispersant, a wetting agent, an emulsifier, a spreader, a stabilizer, a thickener, an antifreeze, a disintegrant, a binder, an antifoaming agent, a film-forming agent, a colorant, a filler and a solvent.
Preferably, the dispersant is selected from: one or more of lignosulfonate, sodium naphthalene sulfonate formaldehyde condensate, formaldehyde condensate sulfate, polycarboxylate, alkylbenzene sulfonate, alkylphenol polyoxyethylene phosphate, alkylphenol polyoxyethylene and fatty acid polyoxyethylene ester.
The wetting agent is selected from: one or more of sodium dodecyl sulfate, calcium dodecyl benzene sulfonate, sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, lignosulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, fatty alcohol sulfate, nonylphenol polyoxyethylene ether, nekal BX, Chinese honeylocust fruit powder and tea seed cake powder.
The emulsifier is selected from: one or more of calcium alkyl benzene sulfonate, benzyl dimethyl phenol polyoxyethylene ether, phenyl phenol polyoxyethylene ether, alkylphenol formaldehyde resin polyoxyethylene ether, phenylethylphenol polyoxyethylene polypropylene ether, tween series and span series.
The spreader is one or more of polyvinyl alcohol, alkyl diphenyl ether disulfonic acid sodium, polytrisiloxane and triethanolamine oleate.
The stabilizer is epoxidized vegetable oil, preferably one or more of epoxidized soybean oil and epoxidized linseed oil.
The thickening agent is selected from: one or more of gelatin, xanthan gum, polyethylene glycol and polyvinyl alcohol.
The antifreeze agent is selected from: one or more of ethylene glycol, propylene glycol, glycerol, sorbitol, urea, and polyethylene glycol.
The disintegrant is selected from: one or more of bentonite, ammonium sulfate, aluminum chloride, urea, magnesium chloride and glucose.
The adhesive is selected from: one or more of diatomite, organic bentonite, cyclodextrin, rosin, starch, PVA and sodium carboxymethyl (ethyl) cellulose.
The defoaming agent is selected from: one or more of organic silicone oil, ethanol, epoxidized soybean oil, silicone compounds, C10-C20 saturated fatty acid compounds and C8-210 fatty alcohol compounds.
The film-forming agent is selected from: one or more of polyvinyl alcohol, polyethylene glycol, gelatin, arabic gum, xanthan gum, high molecular organic compounds, etc.
The filler is selected from: white carbon black, corn starch, kaolin, diatomite, sodium sulfate, ammonium sulfate bentonite, attapulgite and light calcium carbonate.
The solvent is selected from: one or more of turpentine-based oil, petroleum ether, isopropanol, ethanol, ethyl acetate, soybean oil, methyl oleate, white oil, and turpentine methylnaphthalene higher fatty hydrocarbon oil.
The invention also provides a method for treating seeds, which comprises the step of contacting seeds and a medium for sowing the seeds with the insecticidal and bactericidal preparation. The term "seed-sowing medium" refers to any growing environment suitable for the seed to grow plants and/or seedlings, such as soil and other growing media. The insecticidal and bactericidal composition preparation is preferably a suspended seed coating agent which consists of the following components:
the insecticidal and bactericidal composition comprises 5-50% of an insecticidal and bactericidal composition, 2-10% of a dispersing agent, 2-10% of a wetting agent, 0.1-5% of a film forming agent, 1-6% of an antifreeze agent, 0.1-5% of a coloring agent, 1-5% of a thickening agent, 0-2% of a defoaming agent, 0-2% of an adhesive and the balance of water.
The technicians in the field can also add proper plant growth regulator and trace element fertilizer into the suspension seed coating agent according to the characteristics of different crops to promote the growth and the stress resistance.
The insecticidal and fungicidal preparations according to the invention can be used for controlling plant pests and diseases, for preventing or destroying fungi and pests which occur on plants or on plant organs of different useful plants (fruit trees, flowers, leaves, stems, tubers, roots), after which the plant organs which continue to grow are not contaminated by these fungi and pests, or for post-harvest or seed-dressing applications, or for treating plant propagation material, in particular seeds.
Preferably, the insecticidal and bactericidal preparation is used for controlling fungal diseases and pests of rice, wheat, vegetables (such as cucumbers, cabbages, beans, potatoes and tomatoes), bananas, watermelons, corns, peanuts, rapes, fruit trees and ornamental plants.
Preferably, the pests are rice planthoppers, stem borers, leafhoppers, aphids and noctuids.
Preferably, the diseases are rice blast, panicle blast, wheat powdery mildew, cucumber downy mildew and potato late blight.
The method of using the pesticidal and bactericidal agent of the present invention is not particularly limited, and a method generally used in agriculture, preferably a method of treating seeds or spraying, may be used depending on the form of the agent. Before sowing, the seeds are treated by the seed treatment preparation, the active ingredients of the E-imidacloprid guanidine and the bacillus subtilis are mutually synergistic, the E-imidacloprid guanidine can act from different target points at the same time, the seeds are protected in an all-round way, the environmental compatibility is good, the toxicity is low, and the E-imidacloprid seed treatment preparation is safe to the organisms such as human beings, livestock, natural enemies and the like; after seedling emergence or at the time of field planting and at the initial stage of disease occurrence, the pesticide can be sprayed once, so that the plant diseases and insect pests can be effectively prevented and treated, and the lasting period is long.
The invention has the beneficial effects that:
(1) the active ingredients of the composition, namely the guadipyr and the tiadinil, show good complementary action in a specific range, have multi-action targets, can treat insect pests and diseases at the same time, have obvious synergistic action, have field control effect obviously higher than that of a single agent, and provide a new choice for treating the insect pest groups with drug resistance of the existing insecticidal/bactericidal agent.
(2) The active ingredients of the guadipyr and the tiadinil in the insecticidal and bactericidal composition are synergistic, so that the application frequency can be reduced, the application cost of crop pest control can be effectively reduced, and the resistance risk is low.
(3) The insecticidal and bactericidal composition has good safety to crops, has low toxicity to beneficial organisms such as bees and the like, and can be used as an ideal substitute of neonicotinoid insecticides with high toxicity to bees.
Detailed Description
The invention discloses a pesticidal and bactericidal composition, a preparation and application thereof, and a person skilled in the art can realize the pesticidal and bactericidal composition by properly improving process parameters by referring to the content. It is expressly intended that all such similar substitutes and modifications which would be obvious to one skilled in the art are deemed to be included in the invention. While the methods and applications of this invention have been described in terms of preferred embodiments, it will be apparent to those of ordinary skill in the art that variations and modifications in the methods and applications described herein, as well as other suitable variations and combinations, may be made to implement and use the techniques of this invention without departing from the spirit and scope of the invention.
The insecticidal and bactericidal composition, the preparation and the raw materials, the auxiliary agents and the fillers used in the application of the insecticidal and bactericidal composition can be purchased from the market.
The invention is further illustrated by the following examples:
example 1: 51% of guadipyr and tiadinil seed treatment dispersible powder (active ingredient 50:1) 50% of guadipyr, 1% of tiadinil, 3% of sodium dodecyl sulfate, 1.5% of sodium lignosulfonate, 3% of carboxyethyl cellulose, 0.5% of a colorant, 6% of white carbon black and kaolin for 100%. The raw materials are mixed according to a conventional method for preparing the seed treatment dispersible powder to prepare 51 percent of the guadipyr-guadipyr seed treatment dispersible powder.
Example 2: 21% aqueous emulsion of guadipyr and tiadinil (active ingredient 20:1)
20% of penta-imidacloprid guanidine, 1% of tiadinil, 3% of calcium alkylbenzene sulfonate, 5% of phenethyl phenol polyoxyethylene polypropylene ether, 5% of alkylphenol formaldehyde resin polyoxyethylene ether, 2% of polyethylene glycol and deionized water for making up 100%. The raw materials are prepared into 21 percent aqueous emulsion of the guadipyr and the tiadinil according to a conventional method for preparing the aqueous emulsion.
Example 3 44% Guadipyr tiadinil suspension seed coating (active ingredient 10:1)
The pesticide composition comprises 40% of penta-imidacloprid guanidine, 4% of tiadinil, 4% of alkylphenol polyoxyethylene phosphate, 8% of alkylphenol polyoxyethylene, 4% of polyvinyl alcohol, 5% of ethylene glycol, 1% of colorant, 1% of xanthan gum, 3% of sodium carboxymethylcellulose, 0.4% of epoxidized soybean oil, 0.5% of starch and deionized water for making up 100%. The raw materials are mixed according to a conventional method for preparing the suspending agent seed coating to prepare the 44% E Pihong guanidine-tiadinil suspending seed coating.
Example 4 5% Guadipyr tiadinil suspension seed coating (active ingredient 4:1)
4% of penta-imidacloprid guanidine, 1% of tiadinil, 5% of alkylphenol polyoxyethylene, 6% of calcium dodecyl benzene sulfonate, 9% of polyethylene glycol, 10% of propylene glycol, 0.5% of colorant, 4% of xanthan gum, 5% of sodium carboxymethylcellulose and the balance of deionized water to 100%. The raw materials are mixed according to a conventional method for preparing the seed coating of the suspension concentrate to prepare the 5 percent penta imidacloprid guanidine-tiadinil suspension seed coating.
Example 5: 2% aqueous emulsion of guadipyr and tiadinil (active ingredient 1:1)
E, E. The raw materials are mixed according to a conventional method for preparing missible oil to prepare 2% aqueous emulsion of the guadipyr and the tiadinil.
Example 6 20% Guadipyr tiadinil suspension seed coating (active ingredient 1:3)
The pesticide composition comprises, by weight, 5% of penta-imidacloprid guanidine, 15% of tiadinil, 5% of alkylphenol polyoxyethylene phosphate, 5% of alkylphenol polyoxyethylene, 3% of polyvinyl alcohol, 2% of propylene glycol, 0.1% of a coloring agent, 2% of xanthan gum, 2% of sodium carboxymethylcellulose, 0.5% of epoxidized soybean oil, 0.5% of starch and the balance of deionized water to 100%. The raw materials are mixed according to a conventional method for preparing the suspending agent seed coating to prepare the 20% E Pihong guanidine-tiadinil suspending seed coating.
Example 7: 80% guadipyr-tiadinil water dispersible granule (active ingredient 1:7)
The pesticide composition comprises the following components, by weight, 10% of penta-imidacloprid guanidine, 70% of penta-imidacloprid guanidine, 6% of sodium lignin sulfonate, 2% of ammonium sulfate, 3% of polycarboxylate, 2% of starch and the balance of light calcium carbonate to 100%. The raw materials are mixed according to a conventional method for preparing the water dispersible granule to obtain the 80% penta-imidacloprid guanidine tiadinil water dispersible granule.
Example 8: 33% guadipyr tiadinil suspoemulsion (active ingredient 1:10)
3% of penta-imidacloprid guanidine, 30% of tiadinil, 7% of sodium dodecyl benzene sulfonate, 4% of nekal, 4% of polyethylene glycol, 6% of alkylphenol polyoxyethylene ether, 0.3% of silicone compound and the balance of deionized water to 100%. The raw materials are mixed according to a conventional method for preparing a suspoemulsion to prepare the 33% E Ping guanidine-tiadinil suspension.
Example 9 16% Guadipyr tiadinil suspension (active ingredient 1:15)
1% of penta-imidacloprid guanidine, 15% of tiadinil, 6% of saponin powder, 5% of sodium lignosulfonate, 1% of organic silicone oil, 3% of ethylene glycol, 6% of sodium carboxymethylcellulose and the balance of deionized water to 100%. The raw materials are mixed according to a conventional method for preparing the suspending agent to prepare the 16% E Pihong guanidine-tiadinil suspending agent.
Example 10 21% Guadipyr tiadinil suspension (active ingredient 1:20)
1% of penta-imidacloprid guanidine, 20% of tiadinil, 5% of saponin powder, 5% of sodium lignosulfonate, 1% of organic silicone oil, 2% of ethylene glycol, 4% of sodium carboxymethylcellulose and deionized water, wherein the balance is 100%. The raw materials are mixed according to a conventional method for preparing the suspending agent to prepare the 21% E Pihong guanidine-tiadinil suspending agent.
Example 11: 41% penta imidacloprid guanidine tiadinil wettable powder (active ingredient 1:40)
1% of penta-imidacloprid guanidine, 40% of tiadinil, 5% of tea seed powder, 2% of ethanol, 5% of sodium lignosulfonate and diatomite for 100%. The raw materials are mixed according to a conventional method for preparing wettable powder, the mixture is crushed to a certain fineness and then is uniformly mixed to obtain the 41 percent penta-imidacloprid guanidine-tiadinil wettable powder.
Example 12 Water dispersible granules of 51% Guadipyr tiadinil (active ingredient 1:50)
1% of penta-imidacloprid guanidine, 50% of tiadinil, 5% of sodium lignosulfonate, 4% of ammonium sulfate, 5% of polycarboxylate, 2% of starch and the balance of kaolin to 100%. The 51% penta imidacloprid guanidine tiadinil water dispersible granules are prepared by mixing the raw materials according to a conventional method for preparing the water dispersible granules.
Example 13: 61% penta imidacloprid guanidine tiadinil dry powder agent (active component 1:60)
1% of penta-imidacloprid guanidine, 60% of tiadinil, 5% of carboxymethyl cellulose, 4% of sodium dodecyl sulfate, 1% of sodium lignin sulfonate, 3% of polyethylene glycol, 5% of white carbon black and the balance of talcum powder to 100%. The raw materials are crushed and mixed according to a conventional dry powder preparation method to prepare 61% penta imidacloprid guanidine-tiadinil dry powder.
Example 14: 50.5% guadipyr-guadipyr wettable powder (active ingredient 1:100)
E. The raw materials are mixed according to a conventional method for preparing wettable powder, the mixture is crushed to a certain fineness and then is mixed uniformly to form a product, and the 50.5% penta imidacloprid guanidine tiadinil wettable powder is obtained.
Example 15: indoor toxicity determination method for compounding of guadipyr and tiadinil
1. Combined toxicity test of guadipyr and tiadinil in different proportions
1.1 test agent
96% of penta-imidacloprid guanidine technical, 97% of tiadinil technical, and mixed preparations of the penta-imidacloprid guanidine and tiadinil in different proportions
1.2 test targets
Rice blast, cucumber downy mildew, rice planthopper
1.3 indoor toxicity test of rice blast: under the aseptic operation condition, quantitatively adding the pre-melted sterile culture medium into an aseptic conical flask, quantitatively sucking liquid medicines from low concentration to high concentration in sequence, respectively adding into the conical flasks, and fully shaking up. The aliquots were then poured into 9cm diameter dishes with 3 replicates per concentration. And (3) cutting the bacterial cake from the edge of a bacterial colony by using a puncher with the diameter of 5mm under aseptic conditions, inoculating the bacterial cake to the center of a drug-containing flat plate by using an inoculator, enabling the hypha surface to face upwards, covering a dish cover, culturing at a proper temperature, setting a clear water blank control, and observing the result after 48 hours. The diameter of each colony was measured perpendicularly by the cross method once and averaged. And calculating the hypha growth inhibition rate of each treatment concentration on the pathogenic bacteria according to the investigation result.
1.4 indoor virulence determination of rice planthopper: the volume of the capillary micro dropper is 1.0 microliter by adopting a capillary micro dropping method. Dripping the medicinal liquid on the back of rice planthopper larva by head with micro dropper, treating 30 larvae for each concentration, placing each 5 larvae into a culture dish with diameter of 9cm, and placing small amount of feed in the dish for feeding. Clean water was also used as a control. The treated larvae were kept in the rearing room and checked for mortality after 48 h. Data were statistically processed using SPSS software.
1.5 indoor toxicity determination of cucumber downy mildew: the method is the same as 1.3.
The results of the virulence determinations of rice blast, cucumber downy mildew and rice planthopper are shown in Table 1.
TABLE 1 toxicity test results of E Piperidium guanidine and tiadinil in different proportions on rice blast, cucumber downy mildew and rice planthopper
As can be seen from Table 1, after the E-imidacloprid guanidine and the tiadinil are compounded, compared with a single agent, the E-imidacloprid guanidine and the tiadinil have obvious synergistic effect on the control effects of rice blast, cucumber downy mildew and rice planthopper, which is shown in that LC50 and EC50 are obviously reduced, and the synergistic effect is especially obvious within the range of 1: 10-1: 1. Therefore, the combination of the two has strong rationality.
Example 16: pesticide effect test of compounding penta imidacloprid guanidine and tiadinil
1. The efficacy test for preventing and treating wheat powdery mildew comprises the following steps: the compound preparation of the embodiment and single agent of each component are used for carrying out field efficacy test. Selecting windless and rainless weather for testing, wherein rainless weather exists in the whole investigation stage, and wheat powdery mildew is used as a test object. The application method adopts diluted spray (application in the early stage of onset of disease), and a control test is set. And (5) the disease condition of wheat powdery mildew, and calculating the control effect. The control effect is calculated according to the following formula:
disease grading criteria are as follows:
level 0: the whole plant is disease-free;
level 1: the fourth leaf and the leaf sheaths and leaves below the fourth leaf (sword leaf is taken as the first leaf);
and 3, level: the third leaf and the leaf sheaths and leaves below the third leaf are attacked;
and 5, stage: the second leaf and the leaf sheaths and leaves below the second leaf are attacked;
and 7, stage: attack of Jianye leaf and the leaf sheaths and leaves below the Jianye leaf;
and 9, stage: the whole plant is attacked and withered in advance.
The drug effect calculation method comprises the following steps: according to the investigation result, the disease index and the prevention effect are calculated according to the following formula.
The drug effect calculation method comprises the following steps: according to the investigation result, the disease index and the prevention effect are calculated according to the following formula.
In the formula: CK0 and CK1 are disease indexes before and after drug administration in the blank control area respectively; PT0 and PT1 are the disease indexes before and after the drug treatment area.
Table 2: prevention and treatment effect of guadipyr-tiadinil composition on wheat powdery mildew
As can be seen from the table 2, the E-imidacloprid guanidine is ineffective to the wheat powdery mildew, but the E-imidacloprid guanidine and tiadinil can effectively prevent and treat the wheat powdery mildew after being compounded, the prevention and treatment effect is better than that of a single agent, and in the test application range, the E-imidacloprid guanidine has no phytotoxicity to target crops.
2. Pesticide effect test for preventing and treating cabbage aphids
The compound preparation of the embodiment and single agent of each component are used for carrying out field efficacy test. Selecting windless and rainless weather for testing, wherein rainless weather exists in the whole investigation stage, and cabbage aphids are used as test objects. Diluted spray (application at the initial stage of disease) is adopted for application, a control test is set, cabbage aphids are investigated, and the control effect is calculated. The control effect is calculated according to the following formula:
the control effect (%) - (1-T)aCb/TbCa)×100％
In the formula: t isaNumber of individuals surviving control in the treatment area; t isbNumber of individuals surviving before control for treatment area; caNumber of individuals surviving control; caNumber of individuals surviving before control.
The test results are as follows:
table 3: pepper guanidine and tiadinil composition for preventing and treating cabbage aphids
As can be seen from the table 3, tiadinil is ineffective on aphids of cabbage, but the combination of the guadipyr and tiadinil can effectively control the aphids of cabbage, the control effect is better than that of a single dose, and no phytotoxicity is caused to target crops in the application range of the test.
3. Field efficacy test of seed treatment preparation
The examples, comparative examples and clear water controls were used to perform efficacy tests on rice blast control, and the emergence rate and the diseased plant rate were used to measure the degree of control of the agents on rice blast. The field test needs to be arranged in the disease-affected areas of the past year, the cultivation conditions (soil type, fertilizer, sowing period, growth stage and crop plant row spacing) of all test districts need to be uniform and consistent, and the management level is consistent. The examples, comparative examples and clear water controls were set up and each treatment was repeated 4 times in random block arrangements. Each treatment required the seeds to be uniformly coated with the agent, and the application amount of the agent active ingredient was the same for each 1kg of seeds in the examples and comparative examples. And (4) investigating twice, namely the first investigation, namely investigating the seedling emergence conditions of quantitative sowing rows in all the districts and calculating the seedling emergence rate when aligning seedlings in the control districts by clear water. And (4) second investigation, namely investigating the number of plants with diseases of all cells when clear water contrasts the cells to have obvious symptoms, sampling five points on the diagonal of each cell, surveying and connecting 5 clusters and 25 clusters at each point, recording the total number of plants and the number of plants with diseases, and calculating the plant disease rate and the prevention and treatment effect. The formula is as follows.
TABLE 4 contrast table for emergence rate of first investigation after seed dressing and sowing with medicament
| Drug treatment | Emergence of seedlings% |
| Example 1 | 96.5 |
| Example 3 | 97.8 |
| Example 4 | 99.5 |
| Example 6 | 99.6 |
| Example 13 | 95.8 |
| 24% tiadinil suspension | 91.9 |
| Clear water control | —— |
TABLE 5 comparison table for calculating disease and plant rate in second investigation after seed dressing and sowing with medicament
According to the embodiments, the comparative examples and the clear water of the invention, the emergence rate of seeds treated by seed dressing and the control effect on rice sheath blight can be seen, and the emergence rate and the control effect on rice blast of the insecticidal and bactericidal composition preparation provided by the invention are obviously higher than those of a single agent under the condition of the same using amount of the effective components. Compared with a single agent, the dosage can be obviously reduced, the environmental pollution is reduced, and the resistance risk is reduced.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (10)
1. An insecticidal and bactericidal composition is characterized by comprising guadipyr and tiadinil.
2. The insecticidal and bactericidal composition as claimed in claim 1, wherein the mass ratio of the guadipyr to the tiadinil is 1: 100-50: 1.
3. The insecticidal and bactericidal composition as claimed in claim 1, wherein the mass ratio of the guadipyr to the tiadinil is 1: 40-10: 1.
4. The use of the insecticidal and fungicidal composition according to any one of claims 1 to 3 for controlling crop pests.
5. The use according to claim 4, wherein the crop is rice, wheat, vegetables, bananas, watermelons, corn, peanuts, rape, fruit trees, ornamental plants.
6. The use according to claim 4, wherein the pests are rice planthoppers, borers, leafhoppers, aphids and noctuids; the diseases comprise rice blast, wheat powdery mildew, cucumber downy mildew and potato late blight.
7. An insecticidal and bactericidal preparation, which is characterized by comprising the insecticidal and bactericidal composition as defined in any one of claims 1 to 3 and an agriculturally and pharmaceutically acceptable auxiliary material.
8. The insecticidal and bactericidal preparation as claimed in claim 7, wherein the insecticidal and bactericidal composition is present in the insecticidal and bactericidal preparation in an amount of 2 to 80% by weight.
9. The insecticidal and bactericidal preparation according to claim 7, wherein the formulation of the insecticidal and bactericidal preparation is wettable powder, suspending agent, water dispersible granule, suspoemulsion, suspended seed coating agent or seed treatment dispersible powder.
10. The insecticidal and bactericidal formulation as claimed in claim 9, wherein the suspended seed coating agent consists of the following components:
5-50% of insecticidal and bactericidal composition, 2-10% of dispersing agent, 2-10% of wetting agent, 0.1-5% of film forming agent, 1-6% of antifreeze agent, 0.1-5% of colorant, 1-5% of thickening agent, 0-2% of defoaming agent, 0-2% of adhesive and the balance of water.
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Citations (3)
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|---|---|---|---|---|
| CN102812964A (en) * | 2012-09-06 | 2012-12-12 | 中国农业大学 | Pesticide composition containing thiacloprid and validamycin |
| CN106614695A (en) * | 2016-12-29 | 2017-05-10 | 成都格瑞赛斯科技有限公司 | Rice insecticide and fungicide composition containing guadipyr |
| CN107372570A (en) * | 2017-07-07 | 2017-11-24 | 中国农业大学 | A kind of suspension seed-coating agent containing guadipyr and its preparation method and application |
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- 2018-12-20 CN CN201811562040.XA patent/CN111345309A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102812964A (en) * | 2012-09-06 | 2012-12-12 | 中国农业大学 | Pesticide composition containing thiacloprid and validamycin |
| CN106614695A (en) * | 2016-12-29 | 2017-05-10 | 成都格瑞赛斯科技有限公司 | Rice insecticide and fungicide composition containing guadipyr |
| CN107372570A (en) * | 2017-07-07 | 2017-11-24 | 中国农业大学 | A kind of suspension seed-coating agent containing guadipyr and its preparation method and application |
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