CN111315896A - 作为用于鉴定免疫细胞，特别是单核细胞骨髓源性抑制细胞(mMDSC)的表观遗传标志物的ERGIC1 - Google Patents

作为用于鉴定免疫细胞，特别是单核细胞骨髓源性抑制细胞(mMDSC)的表观遗传标志物的ERGIC1 Download PDF

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Publication number
CN111315896A
CN111315896A CN201880071954.8A CN201880071954A CN111315896A CN 111315896 A CN111315896 A CN 111315896A CN 201880071954 A CN201880071954 A CN 201880071954A CN 111315896 A CN111315896 A CN 111315896A
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cells
methylation
mdscs
seq
cpg
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Chinese (zh)
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斯文·欧莱克
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Precision for Medicine GmbH
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Epiontis GmbH
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201880071954.8A 2017-11-09 2018-11-06 作为用于鉴定免疫细胞，特别是单核细胞骨髓源性抑制细胞(mMDSC)的表观遗传标志物的ERGIC1 Withdrawn CN111315896A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102017126248.2 2017-11-09
DE102017126248.2A DE102017126248B4 (de) 2017-11-09 2017-11-09 ERGIC1 als epigenetischer Marker zur Identifizierung von Immunzellen, insbesonderemonozytischem myeloid-abgeleiteten Suppressor-Zellen (mMDSCs)
PCT/EP2018/080235 WO2019091942A1 (en) 2017-11-09 2018-11-06 ERGIC1 AS EPIGENETIC MARKER FOR THE IDENTIFICATION OF IMMUNE CELLS, IN PARTICULAR MONOCYTIC MYELOID-DERIVED SUPPRESSOR CELLS (mMDSCs)

Publications (1)

Publication Number Publication Date
CN111315896A true CN111315896A (zh) 2020-06-19

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CN201880071954.8A Withdrawn CN111315896A (zh) 2017-11-09 2018-11-06 作为用于鉴定免疫细胞，特别是单核细胞骨髓源性抑制细胞(mMDSC)的表观遗传标志物的ERGIC1

Country Status (7)

Country Link
US (1) US11976327B2 (https=)
EP (1) EP3669005B1 (https=)
JP (1) JP2021502809A (https=)
CN (1) CN111315896A (https=)
AU (1) AU2018364335A1 (https=)
DE (1) DE102017126248B4 (https=)
WO (1) WO2019091942A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2869295A1 (en) 2011-05-25 2012-11-29 Brown University Methods using dna methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies
JP6590790B2 (ja) * 2013-04-19 2019-10-16 エピオンティス ゲーエムベーハー 生体サンプルにおける定量的細胞組成を特定する方法
US10190169B2 (en) 2013-06-20 2019-01-29 Immunexpress Pty Ltd Biomarker identification
EP3132055A2 (en) 2014-04-14 2017-02-22 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. A method and kit for determining the tissue or cell origin of dna

Also Published As

Publication number Publication date
JP2021502809A (ja) 2021-02-04
DE102017126248B4 (de) 2019-10-17
US20200347453A1 (en) 2020-11-05
CA3082261A1 (en) 2019-05-16
DE102017126248A1 (de) 2019-05-09
AU2018364335A1 (en) 2020-05-28
WO2019091942A1 (en) 2019-05-16
EP3669005B1 (en) 2026-03-04
US11976327B2 (en) 2024-05-07
EP3669005A1 (en) 2020-06-24

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Application publication date: 20200619

WW01 Invention patent application withdrawn after publication