CN111280330A - Feed additive for solving growth retardation of weaned piglets and preparation method and application thereof - Google Patents

Feed additive for solving growth retardation of weaned piglets and preparation method and application thereof Download PDF

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CN111280330A
CN111280330A CN202010161531.4A CN202010161531A CN111280330A CN 111280330 A CN111280330 A CN 111280330A CN 202010161531 A CN202010161531 A CN 202010161531A CN 111280330 A CN111280330 A CN 111280330A
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powder
parts
mixing
premixing
vitamin
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葛如兴
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Skarn Animal Health Products Shangqiu Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87—Re-use of by-products of food processing for fodder production

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  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)

Abstract

The invention belongs to the field of feed additives, and particularly discloses a feed additive for solving growth obstruction of weaned pigs, a preparation method and application thereof, wherein vitamin B is used1Vitamin B2Vitamin B6Bacillus subtilis, Bacillus licheniformis, Clostridium butyricum, protease, lipase, glucose oxidase, fructus crataegi powder, fructus Hordei Germinatus powder, Massa Medicata Fermentata powder, radix Angelicae sinensis powder, pericarpium Citri Tangerinae powder, rhizoma Drynariae powder, and radix Puerariae powderThe feed comprises raw materials of poria cocos powder, licorice powder, dandelion powder, mulberry leaf powder and motherwort powder, and the raw materials can solve the problem of growth obstruction of weaned piglets, improve the growth speed, enhance the immunity and disease resistance and improve the economic benefit of breeding.

Description

Feed additive for solving growth retardation of weaned piglets and preparation method and application thereof
Technical Field
The invention belongs to the field of feed additives, and particularly relates to a feed additive for solving growth retardation of weaned pigs, and a preparation method and application thereof.
Background
With the rapid development of the breeding industry and the continuous expansion of the pig raising scale, the early weaning technology of piglets is gradually popularized and popularized in the modern pig raising production. The problem of growth obstruction of early weaned piglets is easily caused by the influence of factors such as growth, physiological characteristics, environment, nutrition, stress and the like.
The growth of the weaned piglets is hindered after weaning due to the influence of various factors, namely the growth is shown as follows: several days after weaning, anorexia, malnutrition, growth retardation, not only no weight gain, but also weight loss may occur, which lasts for about 1 week, known as weaning, and after 1 week, there is a slow adaptation and weight gain again.
At present, the reason for the growth obstruction of weaned piglets is as follows: firstly, because the digestive tract of the piglet is lack of acid secretion, and stress generated after weaning reduces gastrointestinal digestive enzymes, the activity is insufficient, the digestion of the feed is influenced, and the dyspepsia diarrhea is easily caused; meanwhile, intestinal villi which plays a very important role in absorption can be broken, reduced and atrophied after weaning, so that the absorption capacity is reduced; the immune protection can be obtained by the piglets in the lactation period, the immune system of the piglets is built only after 3 weeks of age, and 3-10 weeks of age is the immune risk period of the piglets, and the piglets are easy to be attacked by pathogenic bacteria and are easy to have digestive and respiratory diseases. Secondly, the growth and development of piglets are influenced by the change of piggery and the stress of swarming, namely the stress of eating the hard solid pellet feed from eating breast milk, and the psychological stress caused by suddenly leaving sows to lose maternal love and protection. The third is that the disease factors mainly include bacterial viruses such as escherichia coli, mycoplasma, reproductive and respiratory syndrome virus, circovirus and the like, and factors such as parasites, mycotoxin and the like. The reason why the growth of weaned piglets is hindered by 80% is determined by the physiological characteristics of the weaned piglets.
The growth of weaned piglets is retarded, the immunity and disease resistance are reduced, the death rate of the piglets is increased, and the economic benefit of the breeding and the enthusiasm of farmers are seriously influenced. At present, few reports for stopping growth obstruction of weaned piglets through a nutritional approach are reported. The invention researches a nutrition regulation and control technology of weaned pigs to develop a feed additive for solving the problem of hindered growth of the weaned pigs, mainly aims at solving the problem of hindered growth of the weaned pigs, improving the growth speed, enhancing the immunity and disease resistance and improving the culture economic benefit, and gradually becomes a hotspot problem of the current research.
Disclosure of Invention
The invention provides a feed additive for solving growth blockage of weaned pigs, and a preparation method and application thereof, which are used for solving growth blockage of the weaned pigs, improving the growth speed, enhancing the immunity and disease resistance and improving the economic benefit of breeding.
The technical scheme of the invention is realized as follows:
a feed additive for solving growth retardation of weaned piglets comprises the following components in parts by weight:
vitamin B11-8 parts of vitamin B23-15 parts of vitamin B64-15 parts of bacillus subtilis, 10-100 parts of bacillus licheniformis, 5-80 parts of clostridium licheniformis, 1-20 parts of clostridium butyricum, 20-150 parts of protease, 30-150 parts of lipase, 10-100 parts of glucose oxidase, 200-500 parts of hawthorn powder, 150-400 parts of malt powder, 180-450 parts of medicated leaven powder, 30-50 parts of angelica powder, 10-20 parts of orange peel powder, 20-40 parts of drynaria powder, 15-20 parts of kudzu root powder, 7-10 parts of poria cocos powder, 20-30 parts of licorice powder, 5-10 parts of dandelion powder, 5-10 parts of mulberry leaf powder and 30-50 parts of motherwort powder.
Further, the composition comprises the following components in parts by weight: vitamin B13 to 6 parts of vitamin B25-12 parts of vitamin B66-12 parts of bacillus subtilis, 30-60 parts of bacillus subtilis, 20-40 parts of bacillus licheniformis, 5-14 parts of clostridium butyricum, 50-100 parts of protease, 60-120 parts of lipase, 30-70 parts of glucose oxidase, 250-450 parts of hawthorn powder, 200-350 parts of malt powder, 250-350 parts of medicated leaven powder, 30-40 parts of angelica powder, 15-20 parts of orange peel powder, 25-35 parts of drynaria powder, 15-20 parts of kudzu root powder, 8-10 parts of poria cocos powder, 24-28 parts of licorice powder, 5-10 parts of dandelion powder, 8-10 parts of mulberry leaf powder and 35-45 parts of motherwort powder.
Further, the bacterial activity of the bacillus subtilis is 1000 hundred million/g, the bacterial activity of the bacillus licheniformis is 1000 hundred million/g, the bacterial activity of the clostridium butyricum is 10 hundred million/g, the enzyme activity of the protease is 10 ten thousand/g, the enzyme activity of the lipase is 10 ten thousand/g, and the enzyme activity of the glucose oxidase is 10 ten thousand/g.
The invention also provides a preparation method of the feed additive for solving the problem of growth obstruction of the weaned pigs, which comprises the following steps:
1) premixing 1: collecting vitamin B1Vitamin B2Vitamin B6Premixing the hawthorn powder to obtain a premixed material 1;
2) and (2) premixing: premixing bacillus subtilis, bacillus licheniformis, clostridium butyricum and malt powder to obtain a premix 2 material;
3) and (3) premixing: premixing protease, lipase, glucose oxidase, Massa Medicata Fermentata powder, radix Angelicae sinensis powder, pericarpium Citri Tangerinae powder, rhizoma Drynariae powder, radix Puerariae powder, Poria powder, Glycyrrhrizae radix powder, herba Taraxaci powder, folium Mori powder and herba Leonuri powder to obtain premix 3;
4) total mixing: and (3) totally mixing the premix 1 material, the premix 2 material and the premix 3 material to obtain the feed additive for solving the problem of growth retardation of the weaned piglets.
Further, in the step 1), the mixing time of the premixing step 1 is 5-15 min, and the mixing rotation speed is 5-20 r/min.
Further, in the step 2), the mixing time of the premixing 2 is 3-18 min, and the mixing rotating speed is 10-25 r/min.
Further, in the step 3), the mixing time of the premixing 3 is 7-20 min, and the mixing rotating speed is 15-30 r/min.
Further, in the step 4), the mixing time of the total mixing is 10-30 min, and the mixing rotating speed is 20-35 r/min.
The invention also provides an application of the feed additive for solving the problem of growth blockage of the weaned pigs in solving the problem of growth blockage of the weaned pigs.
The invention provides a feed additive for solving the problem of growth obstruction of weaned pigs, a preparation method and application thereof, and vitamin B is used1Vitamin B2Vitamin B6Bacillus subtilis, bacillus licheniformis, clostridium butyricum, protease, lipase, glucose oxidase, hawthorn powder, malt meal and medicated leaven powder as raw materials, and the raw materials can solve the problem of growth obstruction of weaned piglets, improve growth speed and enhanceImmunity and disease resistance, and raising economic benefit of cultivation.
Detailed Description
The invention provides a feed additive for solving growth retardation of weaned piglets, which comprises the following components in parts by weight:
vitamin B11-8 parts of vitamin B23-15 parts of vitamin B64-15 parts of bacillus subtilis, 10-100 parts of bacillus licheniformis, 5-80 parts of clostridium licheniformis, 1-20 parts of clostridium butyricum, 20-150 parts of protease, 30-150 parts of lipase, 10-100 parts of glucose oxidase, 200-500 parts of hawthorn powder, 150-400 parts of malt powder, 180-450 parts of medicated leaven powder, 30-50 parts of angelica powder, 10-20 parts of orange peel powder, 20-40 parts of drynaria powder, 15-20 parts of kudzu root powder, 7-10 parts of poria cocos powder, 20-30 parts of licorice powder, 5-10 parts of dandelion powder, 5-10 parts of mulberry leaf powder and 30-50 parts of motherwort powder.
The invention uses vitamin B1Vitamin B2Vitamin B6The feed comprises the raw materials of bacillus subtilis, bacillus licheniformis, clostridium butyricum, protease, lipase, glucose oxidase, hawthorn powder, malt powder, medicated leaven powder, angelica sinensis powder, tangerine peel powder, drynaria powder, kudzu root powder, poria cocos powder, licorice powder, dandelion powder, mulberry leaf powder and motherwort powder.
In the examples of the present invention, vitamin B13 to 6 parts of vitamin B25-12 parts of vitamin B66-12 parts of bacillus subtilis, 30-60 parts of bacillus subtilis, 20-40 parts of bacillus licheniformis, 5-14 parts of clostridium butyricum, 50-100 parts of protease, 60-120 parts of lipase, 30-70 parts of glucose oxidase, 250-450 parts of hawthorn powder, 200-350 parts of malt powder, 250-350 parts of medicated leaven powder, 30-40 parts of angelica powder, 15-20 parts of orange peel powder, 25-35 parts of drynaria powder, 15-20 parts of kudzu root powder, 8-10 parts of poria cocos powder, 24-28 parts of licorice powder, 5-10 parts of dandelion powder, 8-10 parts of mulberry leaf powder and 35-45 parts of motherwort powder.
It should be noted that the bacterial activity of bacillus subtilis is 1000 hundred million/g, the bacterial activity of bacillus licheniformis is 1000 hundred million/g, the bacterial activity of clostridium butyricum is 10 hundred million/g, the enzymatic activity of protease is 10 ten thousand/g, the enzymatic activity of lipase is 10 ten thousand/g, and the enzymatic activity of glucose oxidase is 10 ten thousand/g.
It is to be noted that the present invention is directed to vitamin B1Vitamin B2Vitamin B6The sources of the bacillus subtilis, the bacillus licheniformis, the clostridium butyricum, the protease, the lipase, the glucose oxidase, the hawthorn powder, the malt meal and the medicated leaven powder are not particularly limited, and the commercial raw materials can be adopted.
The invention also provides a preparation method of the feed additive for solving the problem of growth obstruction of the weaned pigs, which comprises the following steps:
1) premixing 1: collecting vitamin B1Vitamin B2Vitamin B6Premixing the hawthorn powder to obtain a premixed material 1;
2) and (2) premixing: premixing bacillus subtilis, bacillus licheniformis, clostridium butyricum and malt powder to obtain a premix 2 material;
3) and (3) premixing: premixing protease, lipase, glucose oxidase, Massa Medicata Fermentata powder, radix Angelicae sinensis powder, pericarpium Citri Tangerinae powder, rhizoma Drynariae powder, radix Puerariae powder, Poria powder, Glycyrrhrizae radix powder, herba Taraxaci powder, folium Mori powder and herba Leonuri powder to obtain premix 3;
4) total mixing: and (3) totally mixing the premix 1 material, the premix 2 material and the premix 3 material to obtain the feed additive for solving the problem of growth retardation of the weaned piglets.
Wherein, vitamin B1Vitamin B2Vitamin B6The bacillus subtilis, the bacillus licheniformis, the clostridium butyricum, the protease, the lipase, the glucose oxidase, the hawthorn powder, the malt powder, the medicated leaven powder, the angelica sinensis powder, the tangerine peel powder, the drynaria powder, the pueraria powder, the poria cocos powder, the licorice powder, the dandelion powder, the mulberry leaf powder and the motherwort powder are all the same as the above, and no further description is provided herein.
The preparation method is simple, and the prepared feed additive is used for solving the problem of growth obstruction of weaned piglets, improving the growth speed, enhancing the immunity and disease resistance and improving the economic benefit of breeding.
In the step 1), the mixing time of the premixing step 1 is 5-15 min, and the mixing rotating speed is 5-20 r/min. . In the embodiment of the invention, the mixing time of the premix 1 is 7-13 min, and the mixing rotating speed of the premix 1 is 8-15 r/min.
In the step 2), the mixing time of the premixing step 2 is 3-18 min, and the mixing speed is 10-25 r/min. In the embodiment of the invention, the mixing time of the pre-mixing 2 is 6-15 min, and the mixing rotating speed of the pre-mixing 2 is 12-20 r/min.
In the step 3), the mixing time of the premixing 3 is 7-20 min, and the mixing rotating speed is 15-30 r/min. In the embodiment of the invention, the mixing time of the pre-mixing 3 is 10-15 min, and the mixing rotating speed of the pre-mixing 3 is 20-25 r/min.
In the step 4), the mixing time of the total mixing is 10-30 min, and the mixing rotating speed is 20-35 r/min. In the embodiment of the invention, the mixing time of the total mixing is 15-25 min, and the mixing rotating speed of the total mixing is 23-32 r/min.
The invention also provides an application of the feed additive for solving the problem of growth blockage of the weaned pigs in solving the problem of growth blockage of the weaned pigs.
The feed additive for solving the problem of growth blockage of the weaned pigs can solve the problem of growth blockage of the weaned pigs, improve the growth speed, enhance the immunity and disease resistance and improve the breeding economic benefit.
To further illustrate the present invention, the following will describe in detail a feed additive for solving growth retardation of weaned pigs, its preparation method and application, which are provided by the present invention, with reference to the examples, but they should not be construed as limiting the scope of the present invention.
Example 1
1) Premixing 1: according to the weight portion, taking vitamin B14000mg of vitamin B28000mg of vitamin B65000mg of hawthorn powder and 250000mg of hawthorn powder are mixed in a premixing mode 1, the mixing time of the premixing mode 1 is 8min, and the mixing speed of the premixing mode 1 is 12r/min, so that a premixing mode 1 material is obtained;
2) and (2) premixing: taking 35000mg of bacillus subtilis (bacterial viability: 1000 hundred million/g), 32000mg of bacillus licheniformis (bacterial viability: 1000 hundred million/g), 8000mg of clostridium butyricum (bacterial viability: 10 hundred million/g) and 280000mg of malt meal according to parts by weight, and carrying out premixing 2 and mixing for 14min, wherein the mixing speed of the premixing 2 is 22r/min, so as to obtain a material of the premixing 2;
3) and (3) premixing: according to the weight parts, 58000mg of protease (enzyme activity: 10 ten thousand/g), 102000mg of lipase (enzyme activity: 10 ten thousand/g), 38000mg of glucose oxidase (enzyme activity: 10 ten thousand/g), 180000mg of medicated leaven powder, 30000mg of angelica powder, 10000mg of orange peel powder, 20000mg of drynaria powder, 15000mg of radix puerariae powder, 7000mg of tuckahoe powder, 20000mg of liquorice powder, 5000mg of dandelion powder, 5000mg of mulberry leaf powder and 300000mg of motherwort powder are taken for premixing 3 and mixing for 13min, and the premixing 3 is carried out at a mixing speed of 23r/min to obtain a premixing 3 material;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 18min, and the total mixing rotating speed is 28r/min, so as to obtain a total mixed material, namely the feed additive for solving the problem of growth blockage of the weaned piglets.
Example 2
1) Premixing 1: according to the weight portion, taking vitamin B15000mg of vitamin B210000mg of vitamin B68000mg of hawthorn powder and 180000mg of hawthorn powder are mixed in a premixing mode 1, the mixing time of the premixing mode 1 is 10min, and the mixing speed of the premixing mode 1 is 11r/min, so that a premixing mode 1 material is obtained;
2) and (2) premixing: taking 42000mg of bacillus subtilis (bacteria viability: 1000 hundred million/g), 28000mg of bacillus licheniformis (bacteria viability: 1000 hundred million/g), 12000mg of clostridium butyricum (bacteria viability: 10 hundred million/g) and 240000mg of malt meal according to the parts by weight, and carrying out premixing 2 for mixing for 8min, wherein the mixing speed of the premixing 2 is 15r/min, so as to obtain a material of the premixing 2;
3) and (3) premixing: according to the weight parts, 52000mg of protease (enzyme activity: 10 ten thousand/g), 95000mg of lipase (enzyme activity: 10 ten thousand/g), 43000mg of glucose oxidase (enzyme activity: 10 ten thousand/g), 285000mg of medicated leaven powder, 50000mg of angelica powder, 20000mg of orange peel powder, 40000mg of drynaria powder, 20000mg of radix puerariae powder, 10000mg of poria cocos powder, 30000mg of liquorice powder, 10000mg of dandelion powder, 10000mg of mulberry leaf powder and 50000mg of motherwort powder are taken for premixing 3 and mixed for 11min, and the premixing 3 is mixed at a mixing speed of 21r/min for 3 to obtain a premixing 3 material;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 20min, and the total mixing rotating speed is 25r/min, so as to obtain the total mixed material, namely the feed additive for solving the problem of growth retardation of the weaned piglets.
Example 3
1) Premixing 1: according to the weight portion, taking vitamin B14500mg, vitamin B28500mg of vitamin B611000mg and 150000mg of hawthorn powder, and mixing the materials in a premixing step 1 for 12min, wherein the mixing speed of the premixing step 1 is 14r/min, so as to obtain a premixing step 1 material;
2) and (2) premixing: according to the weight parts, 58000mg of bacillus subtilis (bacterial viability: 1000 hundred million/g), 37000mg of bacillus licheniformis (bacterial viability: 1000 hundred million/g), 10000mg of clostridium butyricum (bacterial viability: 10 hundred million/g) and 190000mg of malt meal are taken for premixing 2 and mixing, the mixing time of the premixing 2 is 10min, and the mixing speed of the premixing 2 is 10r/min, so that a premixing 2 material is obtained;
3) and (3) premixing: 94000mg of protease (10 ten thousand per gram), 65000mg of lipase (10 ten thousand per gram), 65000mg of glucose oxidase (10 ten thousand per gram), 307000mg of medicated leaven powder, 30000mg of angelica powder, 15000mg of orange peel powder, 25000mg of drynaria powder, 15000mg of kudzuvine root powder, 8000mg of tuckahoe powder, 24000mg of liquorice powder, 5000mg of dandelion powder, 8000mg of mulberry leaf powder and 35000mg of motherwort powder. Mixing 3 of premix 3 for 12min, and obtaining premix 3 material at 22r/min of mixing speed of 3 of premix;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 17min, and the total mixing rotating speed is 26r/min, so as to obtain a total mixed material, namely the feed additive for solving the problem of growth blockage of the weaned piglets.
Example 4
1) Premixing 1: according to the weight portion, taking vitamin B13500mg of vitamin B211000mg of vitamin B69500mg and 195000mg of fructus crataegi powder, mixing for 9min, and mixing for 1Rotating at a speed of 13r/min to obtain a premixed material 1;
2) and (2) premixing: taking 53000mg of bacillus subtilis (bacteria activity: 1000 hundred million/g), 35,000mg of bacillus licheniformis (bacteria activity: 1000 hundred million/g), 13000mg of clostridium butyricum (bacteria activity: 10 hundred million/g), 220000mg of malt powder, angelica powder, tangerine peel powder, drynaria powder, kudzuvine root powder, tuckahoe powder, liquorice powder, dandelion powder, mulberry leaf powder and motherwort powder according to parts by weight, premixing 2 and mixing for 12min, and the mixing speed of 2 and 18r/min to obtain a material of 2;
3) and (3) premixing: according to the weight parts, 75000mg of protease (enzyme activity: 10 ten thousand/g), 82000mg of lipase (enzyme activity: 10 ten thousand/g), 58000mg of glucose oxidase (enzyme activity: 10 ten thousand/g), 24000mg of medicated leaven powder, 40000mg of angelica powder, 20000mg of orange peel powder, 35000mg of drynaria powder, 20000mg of radix puerariae powder, 10000mg of poria cocos powder, 28000mg of licorice powder, 10000mg of dandelion powder, 10000mg of mulberry leaf powder and 45000mg of motherwort powder are taken. Mixing 3 of premix 3 for 10min, and obtaining premix 3 material at 24r/min of mixing speed of 3 of premix;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 23min, and the total mixing rotating speed is 30r/min, so as to obtain a total mixed material, namely the feed additive for solving the problem of growth blockage of the weaned piglets.
Example 5
1) Premixing 1: according to the weight portion, taking vitamin B15500mg, vitamin B29000mg of vitamin B67500mg and 208000mg of hawthorn powder, mixing the materials in a premixing step 1 for 11min, and obtaining a material in the premixing step 1 at a mixing speed of 9r/min in the premixing step 1;
2) and (2) premixing: according to the weight parts, 48000mg of bacillus subtilis (bacterial viability: 1000 hundred million/g), 22000mg of bacillus licheniformis (bacterial viability: 1000 hundred million/g), 14000mg of clostridium butyricum (bacterial viability: 10 hundred million/g) and 201000mg of malt meal are taken for premixing 2 and mixed, the mixing time of the premixing 2 is 13min, and the mixing speed of the premixing 2 is 16r/min, so that a premixing 2 material is obtained;
3) and (3) premixing: according to the weight parts, 65000mg of protease (enzyme activity: 10 ten thousand/g), 78000mg of lipase (enzyme activity: 10 ten thousand/g), 46000mg of glucose oxidase (enzyme activity: 10 ten thousand/g), 296000mg of medicated leaven powder, 35000mg of angelica powder, 18000mg of orange peel powder, 30000mg of drynaria powder, 17000mg of radix puerariae powder, 9000mg of tuckahoe powder, 26000mg of liquorice powder, 6000mg of dandelion powder, 9000mg of mulberry leaf powder and 40000mg of motherwort powder are taken for premixing 3 and mixing, the premixing 3 is carried out for 14min, the mixing speed of the premixing 3 is 20r/min, and premixed material 3 is obtained;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 25min, and the total mixing rotating speed is 24r/min, so as to obtain a total mixed material, namely the feed additive for solving the problem of growth blockage of the weaned piglets.
Example 6
1) Premixing 1: according to the weight portion, taking vitamin B11000mg of vitamin B23000mg, vitamin B64000mg of hawthorn powder and 200000mg of hawthorn powder, and performing premixing 1 and mixing, wherein the mixing time of the premixing 1 is 11min, and the mixing speed of the premixing 1 is 9r/min, so as to obtain a premixing 1 material;
2) and (2) premixing: taking 10000mg of bacillus subtilis (bacterial viability: 1000 hundred million/g), 5000mg of bacillus licheniformis (bacterial viability: 1000 hundred million/g), 1000mg of clostridium butyricum (bacterial viability: 10 hundred million/g) and 150000mg of malt meal according to parts by weight, and carrying out premixing 2 and mixing for 13min, wherein the mixing speed of the premixing 2 is 16r/min, so as to obtain a material of the premixing 2;
3) and (3) premixing: taking 20000mg of protease (enzyme activity: 10 ten thousand/g), 30000mg of lipase (enzyme activity: 10 ten thousand/g), 10000mg of glucose oxidase (enzyme activity: 10 ten thousand/g), 180000mg of medicated leaven powder, 30000mg of angelica powder, 10000mg of orange peel powder, 20000mg of drynaria powder, 15000mg of radix puerariae powder, 7000mg of tuckahoe powder, 20000mg of liquorice powder, 5000mg of dandelion powder, 5000mg of mulberry leaf powder and 30000mg of motherwort powder according to parts by weight, carrying out premixing 3 for mixing for 14min, and carrying out premixing 3 at a mixing speed of 20r/min to obtain a premixing 3 material;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 25min, and the total mixing rotating speed is 24r/min, so as to obtain a total mixed material, namely the feed additive for solving the problem of growth blockage of the weaned piglets.
Example 7
1) Premixing 1: according to the weight portion, taking vitamin B18000mg of vitamin B215000mg, vitamin B615000mg and 500000mg of hawthorn powder, and mixing the materials in a premixing step 1 for 11min, wherein the mixing speed of the premixing step 1 is 9r/min, so as to obtain a material in the premixing step 1;
2) and (2) premixing: taking 100000mg of bacillus subtilis (bacteria activity: 1000 hundred million/g), 80000mg of bacillus licheniformis (bacteria activity: 1000 hundred million/g), 20000mg of clostridium butyricum (bacteria activity: 10 hundred million/g) and 400000mg of malt meal according to parts by weight, and carrying out premixing 2 and mixing for 13min, wherein the mixing speed of the premixing 2 is 16r/min, so as to obtain a premixing 2 material;
3) and (3) premixing: according to the weight parts, taking 150000mg of protease (enzyme activity: 10 ten thousand/g), 150000mg of lipase (enzyme activity: 10 ten thousand/g), 100000mg of glucose oxidase (enzyme activity: 10 ten thousand/g), 450000mg of medicated leaven powder, 50000mg of angelica powder, 20000mg of orange peel powder, 40000mg of drynaria powder, 20000mg of radix puerariae powder, 10000mg of tuckahoe powder, 30000mg of liquorice powder, 10000mg of dandelion powder, 10000mg of mulberry leaf powder and 50000mg of motherwort powder, and carrying out premixing 3 and mixing for 14min, wherein the premixing 3 is carried out for 3 and the mixing speed is 20r/min, so as to obtain a premixing 3 material;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 25min, and the total mixing rotating speed is 24r/min, so as to obtain a total mixed material, namely the feed additive for solving the problem of growth blockage of the weaned piglets.
Example 8
1) Premixing 1: according to the weight portion, taking vitamin B13000mg, vitamin B25000mg of vitamin B66000mg and 250000mg of hawthorn powder, and performing premixing 1 and mixing, wherein the premixing 1 and mixing time is 11min, and the mixing rotating speed of the premixing 1 is 9r/min, so as to obtain a premixing 1 material;
2) and (2) premixing: taking 30000mg of bacillus subtilis (bacterial viability: 1000 hundred million/g), 20000mg of bacillus licheniformis (bacterial viability: 1000 hundred million/g), 5000mg of clostridium butyricum (bacterial viability: 10 hundred million/g) and 200000mg of malt flour in parts by weight, and carrying out premixing 2 and mixing for 13min, wherein the mixing speed of the premixing 2 is 16r/min, so as to obtain a material of the premixing 2;
3) and (3) premixing: according to the weight parts, taking 50000mg of protease (enzyme activity: 10 ten thousand/g), 60000mg of lipase (enzyme activity: 10 ten thousand/g), 30000mg of glucose oxidase (enzyme activity: 10 ten thousand/g), 250000mg of medicated leaven powder, 30000mg of angelica powder, 15000mg of orange peel powder, 25000mg of drynaria powder, 15000mg of radix puerariae powder, 8000mg of tuckahoe powder, 24000mg of liquorice powder, 5000mg of dandelion powder, 8000mg of mulberry leaf powder and 35000mg of motherwort powder, premixing 3 and mixing for 3, wherein the premixing 3 is carried out for 14min, and the mixing speed of the premixing 3 is 20r/min, so as to obtain a premixing 3 material;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 25min, and the total mixing rotating speed is 24r/min, so as to obtain a total mixed material, namely the feed additive for solving the problem of growth blockage of the weaned piglets.
Example 9
1) Premixing 1: according to the weight portion, taking vitamin B15500mg, vitamin B29000mg of vitamin B67500mg and 208000mg of hawthorn powder, mixing the materials in a premixing step 1 for 11min, and obtaining a material in the premixing step 1 at a mixing speed of 9r/min in the premixing step 1;
2) and (2) premixing: according to the weight parts, 48000mg of bacillus subtilis (bacterial viability: 1000 hundred million/g), 22000mg of bacillus licheniformis (bacterial viability: 1000 hundred million/g), 14000mg of clostridium butyricum (bacterial viability: 10 hundred million/g) and 350000mg of malt flour are taken to be premixed for 2 and mixed, the premixing time for 2 and the mixing speed for 2 and 16r/min are carried out, and the premixed 2 material is obtained;
3) and (3) premixing: taking 100000mg of protease (enzyme activity: 10 ten thousand/g), 120000mg of lipase (enzyme activity: 10 ten thousand/g), 70000mg of glucose oxidase (enzyme activity: 10 ten thousand/g), 350000mg of medicated leaven powder, 40000mg of angelica powder, 20000mg of orange peel powder, 35000mg of drynaria powder, 20000mg of radix puerariae powder, 10000mg of tuckahoe powder, 28000mg of liquorice powder, 10000mg of dandelion powder, 10000mg of mulberry leaf powder and 45000mg of motherwort powder according to parts by weight, premixing 3 for mixing for 14min, and premixing 3 for mixing at a mixing speed of 20r/min to obtain a premixed 3 material;
4) total mixing: and (3) performing total mixing on the premix 1 material, the premix 2 material and the premix 3 material, wherein the total mixing time is 25min, and the total mixing rotating speed is 24r/min, so as to obtain a total mixed material, namely the feed additive for solving the problem of growth blockage of the weaned piglets.
The feed additive prepared in the embodiment 1-5 and used for solving the problem of growth obstruction of the weaned piglets is applied to solving the problem of growth obstruction of the weaned piglets.
The test method comprises the following steps: selecting 120 healthy weaned piglets with close weight in a certain pig farm of Shanghai at the age of 21 days at random, and dividing the weaned piglets into 2 groups, namely an experimental group and a control group, wherein the two groups respectively have 60 heads; each group was repeated 4 times (15 replicates each time), the control group was fed with basal diet, and the experimental group was fed with 0.1% of the feed additive for solving growth retardation of weaned piglets, prepared in example 3, on the basal diet basis for 7 days. The feeding amount of each group is the same.
Wherein the basal ration in the experimental group and the control group is the same, and the basal ration is shown in table 1.
TABLE 1 feed ration composition table
Raw materials The weight parts of the raw materials in 100g basic daily ration
Corn (corn) 37.80
Puffed corn 20.00
Peeled soybean meal 16.30
Whey powder 10.00
Spray-dried plasma protein powder 4.00
Soy protein concentrate 3.00
Imported fish meal 4.00
Soybean oil 1.40
Stone powder 0.50
Calcium hydrogen phosphate 1.10
Salt 0.20
1% premix 1.00
L-lysine hydrochloride 0.20
L-threonine 0.06
DL-methionine 0.04
TABLE 2 Effect of weaned piglets 22-28 days old on Productivity
Figure BDA0002405964320000111
Figure BDA0002405964320000121
Note: a. b-letter shoulder marks indicate significant difference (P < 0.05); a. the c letter shoulder mark indicates that the difference is extremely significant (P <0.01)
And (3) test results: as can be seen from Table 2, the weight of the test group at 28 days is averagely 0.5kg higher than that of the control group and reaches 8.6 percent; the average daily gain (g) of 22-28 days old is 107.14g in the test group, and the average daily gain is 34.29g in the control group, which is 212.5 percent higher, and the difference is very obvious (P is less than 0.01); the daily average feed intake (g) of the head of 22-28 days old, the control group is 126.26g, the test group is 181.56g, the feed intake is improved by 43.8 percent, and the difference is obvious (P is less than 0.05); the material weight ratio of the control group is 3.68, the test group is 1.69, and the difference is very significant (P is less than 0.01).
And (4) conclusion: the feed additive for solving the growth retardation of the weaned piglets, which is prepared in the embodiment 3 and is added into the daily ration in 0.1 percent (mass percentage) within one week of weaning, can obviously improve the daily gain of the weaned piglets and solve the problem of growth retardation of the weaned piglets, and is very valuable to the growth of the piglets.
In conclusion, the above embodiments are merely intended to illustrate the technical solution of the present invention and not to limit, although the present invention has been described by referring to certain preferred embodiments thereof, it should be understood by those of ordinary skill in the art that various changes in form and details may be made therein without departing from the spirit and scope of the present invention as defined by the following claims.

Claims (9)

1. The feed additive for solving the problem of growth retardation of weaned piglets is characterized by comprising the following components in parts by weight:
vitamin B11-8 parts of vitamin B23-15 parts of vitamin B64-15 parts of bacillus subtilis, 10-100 parts of bacillus licheniformis, 5-80 parts of bacillus licheniformis, 1-20 parts of clostridium butyricum, 20-150 parts of protease, 30-150 parts of lipase, 10-100 parts of glucose oxidase, 200-500 parts of hawthorn powder, 150-400 parts of malt powder, medicated leaven powder180-450 parts of angelica powder, 30-50 parts of orange peel powder, 10-20 parts of broken bone powder, 20-40 parts of kudzu root powder, 7-10 parts of tuckahoe powder, 20-30 parts of liquorice powder, 5-10 parts of dandelion powder, 5-10 parts of mulberry leaf powder and 30-50 parts of motherwort powder.
2. The feed additive for solving growth retardation of weaned pigs according to claim 1, is characterized by comprising the following components in parts by weight: vitamin B13 to 6 parts of vitamin B25-12 parts of vitamin B66-12 parts of bacillus subtilis, 30-60 parts of bacillus subtilis, 20-40 parts of bacillus licheniformis, 5-14 parts of clostridium butyricum, 50-100 parts of protease, 60-120 parts of lipase, 30-70 parts of glucose oxidase, 250-450 parts of hawthorn powder, 200-350 parts of malt powder, 250-350 parts of medicated leaven powder, 30-40 parts of angelica powder, 15-20 parts of orange peel powder, 25-35 parts of drynaria powder, 15-20 parts of kudzu root powder, 8-10 parts of poria cocos powder, 24-28 parts of licorice powder, 5-10 parts of dandelion powder, 8-10 parts of mulberry leaf powder and 35-45 parts of motherwort powder.
3. The feed additive for solving growth retardation of weaned pigs according to claim 1 or 2, wherein the bacterial activity of bacillus subtilis is 1000 hundred million/g, the bacterial activity of bacillus licheniformis is 1000 hundred million/g, the bacterial activity of clostridium butyricum is 10 hundred million/g, the enzymatic activity of protease is 10 ten thousand/g, the enzymatic activity of lipase is 10 ten thousand/g, and the enzymatic activity of glucose oxidase is 10 ten thousand/g.
4. A method for preparing a feed supplement for solving the problem of hindered growth of weaned pigs according to any of claims 1 to 3, comprising the steps of:
1) premixing 1: collecting vitamin B1Vitamin B2Vitamin B6Premixing the hawthorn powder to obtain a premixed material 1;
2) and (2) premixing: premixing bacillus subtilis, bacillus licheniformis, clostridium butyricum and malt powder to obtain a premix 2 material;
3) and (3) premixing: premixing protease, lipase, glucose oxidase, Massa Medicata Fermentata powder, radix Angelicae sinensis powder, pericarpium Citri Tangerinae powder, rhizoma Drynariae powder, radix Puerariae powder, Poria powder, Glycyrrhrizae radix powder, herba Taraxaci powder, folium Mori powder and herba Leonuri powder to obtain premix 3;
4) total mixing: and (3) totally mixing the premix 1 material, the premix 2 material and the premix 3 material to obtain the feed additive for solving the problem of growth retardation of the weaned piglets.
5. The preparation method according to claim 4, wherein in the step 1), the mixing time of the pre-mixing step 1 is 5-15 min, and the mixing speed is 5-20 r/min.
6. The preparation method according to claim 4, wherein in the step 2), the mixing time of the pre-mixing 2 is 3-18 min, and the mixing speed is 10-25 r/min.
7. The preparation method according to claim 4, wherein in the step 3), the mixing time of the pre-mixing 3 is 7-20 min, and the mixing rotation speed is 15-30 r/min.
8. The preparation method according to claim 4, wherein in the step 4), the mixing time of the total mixing is 10-30 min, and the mixing rotation speed is 20-35 r/min.
9. Use of a feed supplement according to any of claims 1-3 for addressing growth retardation of weaned pigs.
CN202010161531.4A 2020-03-10 2020-03-10 Feed additive for solving growth retardation of weaned piglets and preparation method and application thereof Pending CN111280330A (en)

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CN109221675A (en) * 2018-11-02 2019-01-18 郑州瑞腾生物工程有限公司 A kind of feed additive for weaning piglet and preparation method thereof
CN109287876A (en) * 2018-11-27 2019-02-01 四川农业大学 A kind of nonreactive feed improving weanling pig feed intake
CN110150494A (en) * 2019-06-25 2019-08-23 黑龙江大牧人牧业有限公司 A kind of piglet strong feed addictive of fruity rush and preparation method thereof
CN110214868A (en) * 2019-06-03 2019-09-10 华北制药集团动物保健品有限责任公司 A kind of mixed feed additive of prevention of diarrhea in piglets and application
CN110604226A (en) * 2018-06-15 2019-12-24 江苏奥迈生物科技有限公司 Diarrhea-preventing growth-promoting composite feed additive for weaned piglets and preparation method thereof

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CN110604226A (en) * 2018-06-15 2019-12-24 江苏奥迈生物科技有限公司 Diarrhea-preventing growth-promoting composite feed additive for weaned piglets and preparation method thereof
CN109221675A (en) * 2018-11-02 2019-01-18 郑州瑞腾生物工程有限公司 A kind of feed additive for weaning piglet and preparation method thereof
CN109287876A (en) * 2018-11-27 2019-02-01 四川农业大学 A kind of nonreactive feed improving weanling pig feed intake
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Application publication date: 20200616