CN111249379A - Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation and preparation method and application thereof - Google Patents
Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation and preparation method and application thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of Chinese herbal medicine compositions for livestock, and particularly relates to a Chinese herbal medicine composition for resisting stress response of cattle in long-distance transportation, and a preparation method and application thereof. According to the theory of traditional Chinese medicine, the traditional Chinese medicinal materials with the functions of nourishing the heart and the liver, relieving convulsion and calming the nerves, tonifying middle-jiao and Qi, strengthening the spleen and nourishing the stomach are selected for treatment, each traditional Chinese medicinal component plays its own role, the division of labor is clear, and the traditional Chinese medicine has a good effect of relieving stress reaction of the cattle after long-distance transportation. The results of the embodiments show that after the formula is used for treatment, the average recovery time of sick cattle is 16-19 days, and the average recovery time of the sick cattle in a normal feeding management group is 38-44 days.
Description
Technical Field
The invention relates to the technical field of veterinary Chinese herbal medicine formula, in particular to a Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation, and a preparation method and application thereof.
Background
With the development of national economy and the improvement of the living standard of people, the consumption concept of meat of people is continuously changed, and the consumption demand of beef is continuously improved. The beef demand is improved, so that the circulation of beef cattle is accelerated, a large amount of allopatric transportation of the cattle is involved, and the northern cattle southern regulation is formed. During or after transportation, partial cattle often have the phenomena of organism immunity reduction, body temperature rise, feed intake reduction, weight reduction, digestive tract or respiratory tract diseases and the like, which all affect the performance of the later-period production performance of the cattle, and the phenomena of elimination, death and the like of the cattle can occur when serious treatment is not timely carried out.
Although the prior art has a traditional Chinese medicine prescription for relieving stress reaction of cattle in long-distance transportation, the traditional Chinese medicine prescription can play a certain relieving role only by feeding a large amount of medicines, and the effect is not obvious.
Disclosure of Invention
The invention aims to provide a Chinese herbal medicine formula for resisting stress reaction of long-distance transportation of cattle, and a preparation method and application thereof.
In order to achieve the above purpose, the invention provides the following technical scheme:
the invention provides a Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation, which comprises the following Chinese herbal medicines in parts by mass: 40-60 parts of rhizoma cyperi, 40-60 parts of elecampane, 70-90 parts of spina date seeds, 70-90 parts of schisandra chinensis, 70-90 parts of codonopsis pilosula, 40-60 parts of pericarpium citri reticulatae, 40-60 parts of astragalus membranaceus and 70-90 parts of liquorice.
Preferably, the Chinese herbal medicine formula comprises: 50 parts of rhizoma cyperi, 50 parts of elecampane, 80 parts of spina date seeds, 80 parts of schisandra chinensis, 80 parts of codonopsis pilosula, 50 parts of pericarpium citri reticulatae, 50 parts of astragalus membranaceus and 80 parts of liquorice.
Preferably, the Chinese herbal medicine formula also comprises auxiliary materials, wherein the Chinese herbal medicine in the Chinese herbal medicine formula accounts for 12-17% by mass, and the auxiliary materials account for 83-88%.
Preferably, the herbal medicine is 15% and the adjuvant is 85%.
Preferably, the auxiliary material is corn flour.
The invention provides a preparation method of a Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation, which comprises the following steps: the Chinese herbal medicines are mixed and then are sequentially dried, crushed and sieved to obtain the Chinese herbal medicine formula.
Preferably, when the Chinese herbal medicine formula further comprises auxiliary materials, the sieving further comprises: mixing the obtained Chinese herbal medicine powder with auxiliary materials to obtain the Chinese herbal medicine formula. Preferably, the drying temperature is 50-60 ℃; the sieving is 60-mesh sieving.
The invention also provides the application of the Chinese herbal medicine formula or the Chinese herbal medicine formula obtained by the preparation method in the technical scheme in the stress response of cattle in long-distance transportation.
Preferably, when the Chinese herbal medicine formula is fed to the cattle after the cattle are transported, the feeding method comprises the following steps: the medicine is taken for 2 times every day and is continuously taken for 16-19 days; the feeding amount is adjusted according to the growth stage of the cattle, and specifically comprises the following steps: feeding 340-360 g of son-calf per head or 600-800 g of adult calf per head or 150-200 g of calf per head per calf per time;
when the Chinese herbal medicine formula is fed to the cattle before the cattle are transported, the feeding method comprises the following steps: feeding for 2 times every day, and continuously feeding for 7 days before transportation; the feeding amount is adjusted according to the growth stage of the cattle, and specifically comprises the following steps: the cattle is fed with 340-360 g/head of son cattle or 600-800 g/head of adult cattle or 150-200 g/head of calf every time.
The invention provides a Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation, which comprises the following Chinese herbal medicines in parts by mass: 40-60 parts of rhizoma cyperi, 40-60 parts of elecampane, 70-90 parts of spina date seeds, 70-90 parts of schisandra chinensis, 70-90 parts of codonopsis pilosula, 40-60 parts of pericarpium citri reticulatae, 40-60 parts of astragalus membranaceus and 70-90 parts of liquorice. According to the invention, according to the traditional Chinese medicine theory, traditional Chinese medicinal materials with the functions of nourishing the heart and tonifying the liver, relieving convulsion and soothing the nerves, tonifying middle-jiao and qi, strengthening the spleen and nourishing the stomach are selected for treatment, wherein the rhizoma cyperi has the functions of soothing the liver and relieving the depression, regulating the flow of qi and regulating the middle-jiao, and nourishing the heart and tonifying the liver; the semen Ziziphi Spinosae has effects of nourishing heart, benefiting liver, relieving convulsion, and tranquilizing; fructus Schisandrae chinensis, radix Codonopsis, and radix astragali have effects in invigorating spleen, replenishing qi, invigorating qi, and promoting fluid production; pericarpium Citri Tangerinae, radix aucklandiae and radix astragali have effects of invigorating spleen and promoting digestion; the liquorice has the effects of tonifying spleen and qi and harmonizing the effects of the other medicines, each traditional Chinese medicine component plays its own role, and the division of labor is clear, so that the liquorice has a good effect of relieving the stress reaction after long-distance transportation.
In addition, the whole traditional Chinese medicine formula has no drug resistance and drug resistance, no drug residue and adverse reaction, avoids the harm of antibiotics and chemical drugs to cattle and the pollution to the environment, and ensures the safety of meat products.
Furthermore, the invention directly and evenly mixes and crushes all the traditional Chinese medicines, adds the corn flour concentrate, evenly mixes and feeds, saves time and labor, and is economical and practical and good in drug effect.
The results of the examples show that the Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation provided by the invention obviously shortens the disease course of the cattle, and has the effects of reducing or eliminating the occurrence of epidemic diseases of the cattle after long-distance transportation and improving the resistance of the cattle.
Detailed Description
The invention provides a Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation, which comprises the following Chinese herbal medicines in parts by mass: 40-60 parts of rhizoma cyperi, 40-60 parts of elecampane, 70-90 parts of spina date seeds, 70-90 parts of schisandra chinensis, 70-90 parts of codonopsis pilosula, 40-60 parts of pericarpium citri reticulatae, 40-60 parts of astragalus membranaceus and 70-90 parts of liquorice.
Unless otherwise specified, the sources of the components in the Chinese herbal medicine formula are not particularly required, and the Chinese herbal medicine formula can be prepared from commercially available products well known to those skilled in the art.
The Chinese herbal medicine formula disclosed by the invention preferably comprises 42-55 parts of rhizoma cyperi by mass, and further preferably comprises 45-50 parts of rhizoma cyperi by mass.
Based on the mass parts of the rhizoma cyperi Chinese herbal medicine, the Chinese herbal medicine formula provided by the invention preferably comprises 45-58 parts of elecampane, and more preferably 50-55 parts of elecampane.
In the embodiment of the present invention, the following may be specifically mentioned: 50 parts of rhizoma cyperi, 50 parts of elecampane, 80 parts of spina date seeds, 80 parts of schisandra chinensis, 80 parts of codonopsis pilosula, 50 parts of pericarpium citri reticulatae, 50 parts of astragalus membranaceus and 80 parts of liquorice.
In the invention, the Chinese herbal medicine formula preferably further comprises auxiliary materials; preferably, the Chinese herbal medicine composition comprises 12-17% of Chinese herbal medicine and 83-88% of auxiliary materials by mass percent, and further preferably comprises 15% of Chinese herbal medicine and 85% of auxiliary materials by mass percent. In the present invention, the auxiliary material is preferably corn flour; the corn meal preferably has a particle size of 20 mesh.
The invention provides a preparation method of a Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation, which comprises the following steps: mixing the raw materials corresponding to the Chinese herbal medicine components, and then sequentially drying, crushing and sieving to obtain the Chinese herbal medicine formula. The invention directly and uniformly mixes and crushes the traditional Chinese medicines, saves time and labor, and is economical, practical and good in drug effect.
In the invention, the drying temperature is preferably 50-60 ℃ and the drying time is 3-5 hours; the screening is preferably a 60 mesh screen.
When the Chinese herbal medicine formula also comprises auxiliary materials, the Chinese herbal medicine powder obtained by sieving is preferably mixed with the auxiliary materials to obtain the Chinese herbal medicine formula. The mixing mode of the Chinese herbal medicine powder and the auxiliary materials does not have special requirements, and the mixing mode known by the technical personnel in the field is adopted.
The invention provides application of the Chinese herbal medicine formula in the technical scheme or the Chinese herbal medicine formula obtained by the preparation method in resisting stress reaction of cattle in long-distance transportation.
In the invention, when the Chinese herbal medicine formula is fed after the cattle are transported, the feeding method comprises the following steps: the medicine is taken for 2 times every day and is continuously taken for 16-19 days; the feeding amount is adjusted according to the growth stage of the cattle by ropes, and specifically comprises the following steps: the daily cattle are fed with 340-360 g/head or adult cattle with 600-800 g/head or calf with 150-200 g/head; furthermore, the medicine is taken before ingestion in the morning and evening. The invention starts to feed after long-distance transportation, and can reduce or eliminate stress reaction of cattle in long-distance transportation.
The Chinese herbal medicine formula can also be fed to the cattle to be transported before the cattle are transported, so that the stress response of long-distance transportation can be prevented; feeding the cattle to be transported for 2 times per day preferably, and continuously feeding for 7 days before transportation; the feeding amount is adjusted according to the growth stage of the cattle, and specifically comprises the following steps: the daily cattle can be fed with 340-360 g/head or the adult cattle can be fed with 600-800 g/head or the calf can be fed with 150-200 g/head. In order to further illustrate the present invention, the following examples are provided to describe the Chinese herbal medicine formulation of the present invention and the preparation method and application thereof in detail, but they should not be construed as limiting the scope of the present invention.
Example 1
The Chinese herbal medicine formula for resisting stress reaction of cattle in long-distance transportation comprises the following components: 60g of rhizoma cyperi, 60g of costustoot, 90g of spina date seed, 90g of Chinese magnoliavine fruit, 90g of codonopsis pilosula, 60g of dried orange peel, 40g of astragalus mongholicus and 70g of liquorice.
The preparation method of the Chinese herbal medicine formula comprises the following steps: weighing various Chinese herbal medicines according to a proportion, mixing the Chinese herbal medicines, drying at 50 ℃, crushing, sieving by a 60-mesh sieve to obtain Chinese herbal medicine powder, and then adding 3kg of corn flour and uniformly mixing to obtain the Chinese herbal medicine formula.
Application example 1
In 2018, after 65 shelve cattle of a certain breeding cooperative society in Yuanyang county, Henan province, shipped from inner Mongolia to local, the cattle have symptoms of depressed spirit, absence of spirit in two eyes, anorexia, abdominal distension, rise in body temperature, rough and disorderly fur, cough, asthma, sticky nasal fluid, diarrhea, emaciation and the like, and the cattle are diagnosed as long-distance transport stress syndrome.
1. Grouping of test animals
The 61 cattle of the batch were randomly divided into 2 groups, namely a normal rearing management group and a treatment group, wherein the normal rearing management group had 30 cattle and the treatment group had 31 cattle.
2. Feeding management
The normal feeding management group carries out feeding management according to the conventional method; the treatment group is treated by the traditional Chinese medicine formula on the basis of conventional feeding management, and the use method of the traditional Chinese medicine formula comprises the following steps: the feed is taken 2 times a day for each day at 350 g/head of cattle, and is taken before ingestion in the early morning and evening.
3. Evaluation of therapeutic Effect
Counting the number of the cattle with diseases, the disease course time (the days from the disease to the healing) of the cattle with diseases and the number of the cattle with deaths. And (4) performing one-factor analysis of variance on all data, and processing and analyzing all data by adopting SPSS.
The statistical results are shown in table 1.
TABLE 1 statistics of the number of cattle with disease, the course of disease and the number of deaths
| Index (I) | Normal feeding management group | Treatment group |
| Number of sick cattle | 25 | 27 |
| Duration/number of days | 41.2±3.23a | 18.6±3.17b |
| Number of dead heads | 0 | 0 |
Note: the data in the same row are marked with different lower case letters to show obvious difference (P < 0.05), the data in the same row are marked with the same or no letters to show the obvious difference (P > 0.05)
As can be seen from Table 1, the number of cattle in the treatment group was equivalent to that in the normal feeding management group, the number of cattle with disease was equivalent, there was no statistical difference, and none of the cattle died. But the disease course time of the cattle with the disease is obviously different (P is less than 0.05), the cattle with the disease can be cured in 18.6 days on average after being treated by the Chinese herbal medicine, and the cattle with the disease can be cured in 41.2 days on average in a normal feeding management group.
Example 2
The Chinese herbal medicine formula for resisting stress reaction of cattle in long-distance transportation comprises the following components: 60g of rhizoma cyperi, 60g of costustoot, 90g of spina date seed, 90g of Chinese magnoliavine fruit, 90g of codonopsis pilosula, 60g of dried orange peel, 40g of astragalus mongholicus and 70g of liquorice.
The preparation method of the Chinese herbal medicine formula comprises the following steps: weighing various Chinese herbal medicines according to a proportion, mixing the Chinese herbal medicines, drying at 50 ℃, crushing, sieving by a 60-mesh sieve to obtain Chinese herbal medicine powder, and then adding 3kg of corn flour and uniformly mixing to obtain the Chinese herbal medicine formula.
The using method comprises the following steps: the feed is taken for 360 g/head of cattle every time, 2 times per day, and before ingestion in the early morning and evening.
Application example 2
In 2018, 9 months, after 213 shelf cattle of a certain breeding company in Yuanyang county in Henan province are transported to the local place from inner Mongolia, the cattle have the symptoms of depressed spirit, unconsciousness of eyes, anorexia, abdominal distension, firm rumen, content full of heavy breath, even odor, increased body temperature, rough and disordered hair, cough, asthma, viscous or purulent nasal fluid, diarrhea, hematochezia, extreme emaciation and the like, and the symptoms are diagnosed as long-distance transport stress syndrome.
1. Grouping of test animals
The 213 cattle in this batch were randomly divided into 2 groups, namely a normal rearing management group and a treatment group, wherein the normal rearing management group had 106 cattle and the treatment group had 107 cattle.
2. Feeding management
The normal feeding management group carries out feeding management according to the conventional method; the treatment group is treated by the medicine of the formula on the basis of conventional feeding management.
3. Evaluation of therapeutic Effect
Counting the number of the cattle with diseases, the disease course time (the days from the disease to the healing) of the cattle with diseases and the number of the cattle with deaths. And (4) performing one-factor analysis of variance on all data, and processing and analyzing all data by adopting SPSS. The statistical results are shown in table 2.
TABLE 2 statistics of the number of cattle with disease, the duration of disease and the number of dead cattle
| Index (I) | Normal feeding management group | Treatment group |
| Number of sick cattle | 90 | 88 |
| Duration/number of days | 43.5±4.31a | 17.2±3.26b |
| Number of dead heads | 2 | 0 |
Note: the data in the same row are marked with different lower case letters to show obvious difference (P < 0.05), the data in the same row are marked with the same or no letters to show the obvious difference (P > 0.05)
As can be seen from Table 2, the number of cattle in the treatment group was comparable to that in the normal feeding management group and that in the affected cattle, there was no statistical difference.
No cattle in the treatment group died, and 2 cattle in the normal feeding management group died. The disease course time of the cattle with the disease is obviously different (P is less than 0.05), the cattle with the disease can be cured within 17.2 days on average after being treated by the Chinese herbal medicine, and the cattle with the disease can be cured within 43.5 days on average in a normal feeding management group.
Example 3
The Chinese herbal medicine formula for resisting stress reaction of cattle in long-distance transportation comprises the following components: 50g of rhizoma cyperi, 50g of costustoot, 90g of spina date seed, 80g of Chinese magnoliavine fruit, 70g of codonopsis pilosula, 50g of dried orange peel, 50g of astragalus mongholicus and 80g of liquorice.
The preparation method of the Chinese herbal medicine formula comprises the following steps: weighing various Chinese herbal medicines according to a proportion, mixing the Chinese herbal medicines, drying at 50 ℃, crushing, sieving by a 60-mesh sieve to obtain Chinese herbal medicine powder, and then adding 3kg of corn flour and uniformly mixing to obtain the Chinese herbal medicine formula.
The using method comprises the following steps: the feed is taken 2 times per day at a dose of 350g per cow, and is taken before ingestion in the early morning and evening.
Application example 3
In 2016, 9 and 13 days, after 71 cattle in Yuanyang county of Henan province are transported to local places from inner Mongolia, the cattle have symptoms of depression, poor appetite, weakness in chewing, anorexia, abdominal distension, belching, reduction in rumination, rise in body temperature, rough and disorderly fur, cough, asthma, diarrhea, hematochezia, emaciation and the like, and are diagnosed as long-distance transportation stress syndrome.
1. Grouping of test animals
The 71 cattle of the batch were randomly divided into 2 groups, namely a normal rearing management group and a treatment group, wherein the normal rearing management group had 35 cattle and the treatment group had 36 cattle.
2. Feeding management
The normal feeding management group carries out feeding management according to the conventional method; the treatment group is treated by the medicine of the formula on the basis of conventional feeding management.
3. Evaluation of therapeutic Effect
Counting the number of the cattle with diseases, the disease course time (the days from the disease to the healing) of the cattle with diseases and the number of the cattle with deaths. And (4) performing one-factor analysis of variance on all data, and processing and analyzing all data by adopting SPSS.
The statistical results are shown in table 3.
TABLE 3 statistics of the number of cattle with disease, the duration of disease and the number of dead cattle
| Index (I) | Normal feeding management group | Treatment group |
| Number of sick cattle | 28 | 29 |
| Duration/number of days | 38.7±4.82a | 16.5±3.04b |
| Number of dead heads | 1 | 0 |
Note: the data in the same row are marked with different lower case letters to show obvious difference (P < 0.05), the data in the same row are marked with the same or no letters to show the obvious difference (P > 0.05)
As can be seen from Table 3, the number of cattle in the treatment group was equivalent to that in the normal rearing and management group and that in the affected cattle, and there was no statistical difference.
No cattle in the treatment group died, and 1 cattle in the normal feeding management group died. The disease course time of the cattle with the disease is obviously different (P is less than 0.05), the cattle with the disease can be cured within 16.5 days on average after being treated by the Chinese herbal medicine, and the cattle with the disease can be cured within 38.7 days on average in a normal feeding management group.
The embodiments show that the Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation obviously shortens the time of the disease course of the cattle, reduces or eliminates the occurrence of epidemic diseases of the cattle after long-distance transportation, improves the resistance of the cattle, and obviously improves the economic benefit of cattle farms.
Although the present invention has been described in detail with reference to the above embodiments, it is only a part of the embodiments of the present invention, not all of the embodiments, and other embodiments can be obtained without inventive step according to the embodiments, and the embodiments are within the scope of the present invention.
Claims (10)
1. The Chinese herbal medicine formula for resisting stress response of cattle in long-distance transportation is characterized by comprising the following Chinese herbal medicines in parts by mass: 40-60 parts of rhizoma cyperi, 40-60 parts of elecampane, 70-90 parts of spina date seeds, 70-90 parts of schisandra chinensis, 70-90 parts of codonopsis pilosula, 40-60 parts of pericarpium citri reticulatae, 40-60 parts of astragalus membranaceus and 70-90 parts of liquorice.
2. The Chinese herbal medicine formula of claim 1, which is characterized by comprising the following Chinese herbal medicines in parts by mass: 50 parts of rhizoma cyperi, 50 parts of elecampane, 80 parts of spina date seeds, 80 parts of schisandra chinensis, 80 parts of codonopsis pilosula, 50 parts of pericarpium citri reticulatae, 50 parts of astragalus membranaceus and 80 parts of liquorice.
3. The Chinese herbal medicine formula as claimed in claim 1 or 2, further comprising an auxiliary material, wherein the Chinese herbal medicine in the Chinese herbal medicine formula accounts for 12-17% and the auxiliary material accounts for 83-88% by mass.
4. The herbal formulation of claim 3, wherein the herbal formulation is 15% and the adjuvant is 85%.
5. The herbal formulation of claim 3, wherein the adjuvant is corn flour.
6. A method of preparing a herbal formulation as claimed in any one of claims 1 to 5, comprising the steps of: mixing the raw materials corresponding to the Chinese herbal medicine components, and then sequentially drying, crushing and sieving to obtain the Chinese herbal medicine formula.
7. The method of claim 6, wherein when the herbal formulation further comprises an adjuvant, the sieving further comprises: mixing the obtained Chinese herbal medicine powder with auxiliary materials to obtain the Chinese herbal medicine formula.
8. The method for preparing according to claim 6 or 7, wherein the temperature for drying is 50 ℃; the sieving is 60-mesh sieving.
9. Use of a herbal formulation according to any one of claims 1 to 5 or a herbal formulation obtained by a method according to any one of claims 6 to 8 for combating stress in cattle over long-distance transport.
10. The use of claim 9, wherein when the herbal formulation is fed after cattle transport, the feeding method is: the medicine is taken for 2 times every day and is continuously taken for 16-19 days; the feeding amount is adjusted according to the growth stage of the cattle, and specifically comprises the following steps: feeding 340-360 g of son cattle per head or 600-800 g of adult cattle per head or 150-200 g of calf per head each time;
when the Chinese herbal medicine formula is fed to the cattle before the cattle are transported, the feeding method comprises the following steps: feeding for 2 times every day, and continuously feeding for 7 days before transportation; the feeding amount is adjusted according to the growth stage of the cattle, and specifically comprises the following steps: the calf nursing liquid is used for feeding 340-360 g of son cows per time, 600-800 g of adult cows per time or 150-200 g of calves per time.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2793234C1 (en) * | 2022-09-08 | 2023-03-30 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Алтайский государственный аграрный университет" (ФГБОУ ВО Алтайский ГАУ) | Method for increasing the adaptive capacity of calves |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2793234C1 (en) * | 2022-09-08 | 2023-03-30 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Алтайский государственный аграрный университет" (ФГБОУ ВО Алтайский ГАУ) | Method for increasing the adaptive capacity of calves |
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Application publication date: 20200609 |