CN111228358A - Lung moistening medicine and preparation method thereof - Google Patents

Abstract

The invention relates to the technical field of traditional Chinese medicine products, in particular to a lung moistening medicine and a preparation method thereof. The technical scheme is as follows: the lung moistening medicine consists of the following components in parts by mass: 20-30 parts of honeysuckle, 12-17 parts of selfheal, 15-20 parts of houttuynia cordata, 8-12 parts of kudzu root, 8-12 parts of dandelion, 6-12 parts of perilla fruit, 6-10 parts of chrysanthemum and 5-10 parts of liquorice. The preparation method of the lung moistening medicine is characterized by comprising the following steps: a) weighing; b) respectively oven drying flos Lonicerae, Prunellae Spica, herba Houttuyniae, radix Puerariae, herba Taraxaci, fructus Perillae, flos Chrysanthemi, and Glycyrrhrizae radix, and pulverizing; c) mixing the medicinal powder obtained in the step b) with water in proportion to prepare a soft material; d) preparing the soft material obtained in the step c) into wet particles, performing shot blasting and drying. The invention provides a medicine for effectively treating upper respiratory tract infection and a preparation method thereof.

Description

Lung moistening medicine and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicine products, in particular to a lung moistening medicine and a preparation method thereof.

Background

The Chinese medicinal decoction pieces are prepared by specially processing Chinese medicinal materials according to the requirements of dialectical administration, dispensing and preparation under the guidance of the Chinese medicinal theory. The traditional Chinese medicine decoction pieces are the characteristics of traditional Chinese medicine, are not only used for clinical prescription medication directly according to the principle of treatment based on syndrome differentiation, but also are raw materials for preparing Chinese patent medicine. The traditional Chinese medicine decoction pieces are the material basis for forming decoction, and with the development of times and the progress of science and technology, the defects of inconvenient taking and unstable quality of the traditional decoction pieces are gradually highlighted, thereby influencing the clinical application and restricting the development of clinical subjects of traditional Chinese medicine. In addition, the traditional Chinese medicine decoction pieces always have the phenomena of lagged processing method, improper softening pretreatment of the raw medicinal materials and the like, and are sold directly after being processed by the methods of moistening, cutting, selecting, steaming, boiling and the like for a long time, and the influences of processing conditions, equipment, environment, packaging storage, sales means of a manual weighing scale and the like cause three influences and two disadvantages on the traditional Chinese medicine decoction pieces, namely influence on accurate formula metering, influence on storage quality of the decoction pieces, influence on the decocting rate of effective ingredients of the medicines, and are not beneficial to the sanitation, storage and transportation of the decoction pieces.

The flos Lonicerae is dried bud or flower of Lonicera Japonica flos, Lonicera hypoglauca Miq, Lonicera confusa or Lonicera dasystyla of Caprifoliaceae. Recent pharmacological experiments and clinical application prove that the honeysuckle has stronger antibacterial action and better treatment effect on various pathogenic bacteria. The Chinese patent application No. 201110312031.7 provides a processing method of honeysuckle decoction pieces, which adopts the technical scheme that the honeysuckle decoction pieces are cleaned to remove impurities, subjected to steam deactivation, dehumidified by cool air, dried by hot air, naturally cooled, packaged and warehoused. The traditional honeysuckle decoction pieces as described in the patent are prepared by processing honeysuckle through the steps of removing impurities, cleaning, cutting and drying, and are bulky and fluffy and difficult to store and package.

However, the existing honeysuckle product has single function, only can play a role of clearing heat, and is difficult to be used as a medicine. While upper respiratory tract infection usually has multiple symptoms, the single honeysuckle product is difficult to effectively treat the upper respiratory tract infection.

Disclosure of Invention

The invention overcomes the defects of the prior art, provides the lung-moistening medicine for effectively treating the upper respiratory tract infection and the preparation method thereof, and solves the problem that the existing honeysuckle product has poor treatment effect on the upper respiratory tract infection.

In order to solve the technical problems, the invention adopts the following technical scheme:

the lung moistening medicine consists of the following components in parts by mass: 20-30 parts of honeysuckle, 12-17 parts of selfheal, 15-20 parts of houttuynia cordata, 8-12 parts of kudzu root, 8-12 parts of dandelion, 6-12 parts of perilla fruit, 6-10 parts of chrysanthemum and 5-10 parts of liquorice.

As a preferred embodiment of the present invention, the composition is composed of, by mass: 25 parts of honeysuckle, 14 parts of selfheal, 17 parts of houttuynia cordata, 10 parts of kudzu root, 10 parts of dandelion, 9 parts of perilla fruit, 8 parts of chrysanthemum and 7 parts of liquorice.

As a preferred embodiment of the present invention, the composition is composed of, by mass: 30 parts of honeysuckle, 17 parts of selfheal, 20 parts of houttuynia cordata, 12 parts of kudzu root, 12 parts of dandelion, 12 parts of perilla fruit, 10 parts of chrysanthemum and 10 parts of liquorice.

As a preferred embodiment of the present invention, the composition is composed of, by mass: 20 parts of honeysuckle, 12 parts of selfheal, 15 parts of houttuynia cordata, 8 parts of kudzu root, 8 parts of dandelion, 6 parts of perilla fruit, 6 parts of chrysanthemum, 5 parts of liquorice and 3 parts of microcrystalline cellulose.

A preparation method of a lung moistening medicine comprises the following steps:

a) weighing: weighing 10-15 parts of honeysuckle, 12-17 parts of selfheal, 15-20 parts of houttuynia cordata, 8-12 parts of kudzu vine root, 8-12 parts of dandelion, 6-12 parts of perilla fruit, 6-10 parts of chrysanthemum and 5-10 parts of liquorice;

b) respectively drying and crushing honeysuckle, selfheal, houttuynia cordata, kudzu vine root, dandelion, perilla fruit, chrysanthemum and liquorice to obtain powder of each component;

c) mixing the medicinal powder obtained in the step b) with water according to the weight ratio of 1: 0.6-0.95 to prepare a soft material;

d) preparing the soft material obtained in the step c) into wet granules, placing the wet granules into a centrifugal ball rolling machine for ball blasting, drying the prepared wet shot blasting at the temperature of 60-105 ℃, taking out, placing to room temperature, sieving, and taking out 10-24-mesh shot blasting.

As a preferable scheme of the invention, in the step d), the process parameters of the shot blasting process are the polishing rotation speed of 600-650 rpm and the polishing time of 15-20 min.

Compared with the prior art, the invention has the beneficial effects that:

the invention prepares the pills by pulverizing and mixing the honeysuckle, the selfheal, the houttuynia cordata, the kudzu vine root, the dandelion, the perilla fruit, the chrysanthemum and the liquorice according to a certain proportion, and the medicines supplement each other and have the effects of clearing away heat and toxic material, eliminating phlegm and relieving cough, reducing swelling and relieving pain, inducing diuresis and freeing strangury, relieving cough and asthma, moistening lung and widening intestines, and the like. Because the medicine has the effects, the medicine can be used for treating diseases such as pneumonia, pharyngitis, rhinitis, cold and common cold, respiratory tract infection, serious respiratory tract infection and the like. Meanwhile, the preparation process is easy to stabilize and uniform, the quality is controllable, and the development direction of modern research of the traditional Chinese medicine is met. The traditional Chinese medicine composition for treating upper respiratory tract infection has the characteristics of convenience in taking, controllable quality and good curative effect.

Detailed Description

The present invention will be described in detail below.

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

Example 1:

the medicine of the invention comprises the following components by mass: 25 parts of honeysuckle, 14 parts of selfheal, 17 parts of houttuynia cordata, 10 parts of kudzu root, 10 parts of dandelion, 9 parts of perilla fruit, 8 parts of chrysanthemum and 7 parts of liquorice.

The preparation process comprises the following steps:

a) weighing: weighing 25 parts of honeysuckle, 14 parts of selfheal, 17 parts of houttuynia cordata, 10 parts of kudzu root, 10 parts of dandelion, 9 parts of perilla fruit, 8 parts of chrysanthemum and 7 parts of liquorice;

b) respectively drying and crushing honeysuckle, selfheal, houttuynia cordata, kudzu vine root, dandelion, perilla fruit, chrysanthemum and liquorice to obtain powder of each component;

c) mixing the medicinal powder obtained in the step b) with water according to the weight ratio of 1: 0.6-0.95 to prepare a soft material;

d) and c), preparing the soft material obtained in the step c) into wet granules, placing the wet granules into a centrifugal ball rolling machine for ball blasting, drying the prepared wet shot blasting at the temperature of 60-105 ℃, taking out the wet shot blasting, placing the dried wet shot blasting to room temperature, sieving the dried wet shot blasting, and taking 10-24-mesh shot blasting, wherein the ball blasting rotation speed is 600-650 rpm, and the ball blasting time is 15-20 min.

The invention prepares pills by pulverizing and mixing 25 parts of honeysuckle, 14 parts of selfheal, 17 parts of houttuynia cordata, 10 parts of kudzu root, 10 parts of dandelion, 9 parts of perilla fruit, 8 parts of chrysanthemum and 7 parts of liquorice, and the medicines supplement each other, and have the effects of clearing away heat and toxic materials, removing phlegm and relieving cough, reducing swelling and relieving pain, inducing diuresis and treating stranguria, relieving cough and asthma, moistening lung and widening intestines and the like. Because the medicine has the effects, the medicine can be used for treating diseases such as pneumonia, pharyngitis, rhinitis, cold and common cold, respiratory tract infection, serious respiratory tract infection and the like. Meanwhile, the preparation process is easy to stabilize and uniform, the quality is controllable, and the development direction of modern research of the traditional Chinese medicine is met. The traditional Chinese medicine composition for treating upper respiratory tract infection has the characteristics of convenience in taking, controllable quality and good curative effect.

Example 2:

the medicine of the invention comprises the following components by mass: 30 parts of honeysuckle, 17 parts of selfheal, 20 parts of houttuynia cordata, 12 parts of kudzu root, 12 parts of dandelion, 12 parts of perilla fruit, 10 parts of chrysanthemum and 10 parts of liquorice.

The preparation process comprises the following steps:

a) weighing: weighing 30 parts of honeysuckle, 17 parts of selfheal, 20 parts of houttuynia cordata, 12 parts of kudzu root, 12 parts of dandelion, 12 parts of perilla fruit, 10 parts of chrysanthemum and 10 parts of liquorice;

b) respectively drying and crushing honeysuckle, selfheal, houttuynia cordata, kudzu vine root, dandelion, perilla fruit, chrysanthemum and liquorice to obtain powder of each component;

c) mixing the medicinal powder obtained in the step b) with water according to the weight ratio of 1: 0.6-0.95 to prepare a soft material;

d) and c), preparing the soft material obtained in the step c) into wet granules, placing the wet granules into a centrifugal ball rolling machine for ball blasting, drying the prepared wet shot blasting at the temperature of 60-105 ℃, taking out the wet shot blasting, placing the dried wet shot blasting to room temperature, sieving the dried wet shot blasting, and taking 10-24-mesh shot blasting, wherein the ball blasting rotation speed is 600-650 rpm, and the ball blasting time is 15-20 min.

30 parts of honeysuckle, 17 parts of selfheal, 20 parts of houttuynia cordata, 12 parts of kudzu vine root, 12 parts of dandelion, 12 parts of perilla fruit, 10 parts of chrysanthemum and 10 parts of liquorice are pulverized and mixed to prepare pills, and the medicines supplement each other, so that the pills have the effects of clearing away heat and toxic materials, removing phlegm and stopping cough, reducing swelling and relieving pain, promoting urination and treating stranguria, relieving cough and asthma, moistening lung and widening intestines and the like. Because the medicine has the effects, the medicine can be used for treating diseases such as pneumonia, pharyngitis, rhinitis, cold and common cold, respiratory tract infection, serious respiratory tract infection and the like. Meanwhile, the preparation process is easy to stabilize and uniform, the quality is controllable, and the development direction of modern research of the traditional Chinese medicine is met. The traditional Chinese medicine composition for treating upper respiratory tract infection has the characteristics of convenience in taking, controllable quality and good curative effect.

Example 3:

the medicine of the invention comprises the following components by mass: 20 parts of honeysuckle, 12 parts of selfheal, 15 parts of houttuynia cordata, 8 parts of kudzu root, 8 parts of dandelion, 6 parts of perilla fruit, 6 parts of chrysanthemum, 5 parts of liquorice and 3 parts of microcrystalline cellulose.

The preparation process comprises the following steps:

a) weighing: weighing 20 parts of honeysuckle, 12 parts of selfheal, 15 parts of houttuynia cordata, 8 parts of kudzu root, 8 parts of dandelion, 6 parts of perilla fruit, 6 parts of chrysanthemum, 5 parts of liquorice and 3 parts of microcrystalline cellulose;

b) respectively drying and crushing honeysuckle, selfheal, houttuynia cordata, kudzu vine root, dandelion, perilla fruit, chrysanthemum and liquorice to obtain powder of each component;

c) mixing the medicinal powder obtained in the step b) with water according to the weight ratio of 1: 0.6-0.95 to prepare a soft material;

d) and c), preparing the soft material obtained in the step c) into wet granules, placing the wet granules into a centrifugal ball rolling machine for ball blasting, drying the prepared wet shot blasting at the temperature of 60-105 ℃, taking out the wet shot blasting, placing the dried wet shot blasting to room temperature, sieving the dried wet shot blasting, and taking 10-24-mesh shot blasting, wherein the ball blasting rotation speed is 600-650 rpm, and the ball blasting time is 15-20 min.

20 parts of honeysuckle, 12 parts of selfheal, 15 parts of houttuynia cordata, 8 parts of kudzu vine root, 8 parts of dandelion, 6 parts of perilla fruit, 6 parts of chrysanthemum, 5 parts of liquorice and 3 parts of microcrystalline cellulose are prepared into powder and mixed to prepare pills, and the medicines supplement each other and have the effects of clearing away heat and toxic materials, eliminating phlegm and relieving cough, reducing swelling and relieving pain, inducing diuresis and freeing strangury, relieving cough and asthma, moistening lung and widening intestines and the like. Because the medicine has the effects, the medicine can be used for treating diseases such as pneumonia, pharyngitis, rhinitis, cold and common cold, respiratory tract infection, serious respiratory tract infection and the like. Meanwhile, the preparation process is easy to stabilize and uniform, the quality is controllable, and the development direction of modern research of the traditional Chinese medicine is met. The traditional Chinese medicine composition for treating upper respiratory tract infection has the characteristics of convenience in taking, controllable quality and good curative effect.

Case 1

Wu Chi, female, age 35, with persistent high fever for 4 days, accompanied by aversion to cold, headache, dry throat, red tongue with yellow coating, floating and rapid pulse. After the intravenous drip therapy of ceftizoxime, ribavirin and the like is carried out in the hospital, the illness state is not obviously improved, and the physical examination is as follows: the body temperature is 39.6 ℃, the pharynx is congested, the tonsil on both sides is slightly enlarged, the viral upper respiratory tract infection is diagnosed in western medicine, and the wind-warm syndrome is distinguished in traditional Chinese medicine. The method is to dispel wind, release exterior syndrome, clear heat and remove toxicity. The formula of the embodiment 1 is adopted, and three doses are given, one dose is taken every day. After taking the above three doses, the patient can get rid of the body and calm.

Case 2

Li Shi, male, 28 years old, will be diagnosed in 3 days mainly due to fever. The patient has fever for 3 days, the temperature fluctuation is 37-39 ℃, the patient is accompanied with nasal discharge, sneeze and cough, parents give treatment such as 'Meilin' and 'Isatis root granules', and the patient relapses after temporary fever subsidence. When the patient is in intravenous drip for 2 days, the fever still occurs, and the body temperature rises to 39.4 ℃. Physical examination: pharyngeal congestion (+++), swollen tonsil I; viral upper respiratory tract infection was diagnosed in western medicine. The syndrome differentiation of the traditional Chinese medicine is wind-heat type common cold. By adopting the formula of the example 1, three doses are given, one dose is taken every day, and after 3 doses are taken, all symptoms disappear and the clinical cure is realized.

Case 3

Tang Dynasty, women, age 30, fever for 1 day, aversion to wind, slight headache, flushing, thirst, sometimes cough, anorexia, dry stool and yellow urine. Body examination: t38.9 ℃, pharyngeal congestion, and no abnormality in cardiopulmonary examination. Viral upper respiratory tract infection was diagnosed in western medicine. The syndrome differentiation of the traditional Chinese medicine is wind-heat type common cold. The formulation of example 1 was used. After the medicine is taken twice, the patient sweats more, the body temperature is gradually reduced, the body temperature is reduced to normal after 24 hours, no headache exists, the cough basically disappears, and the patient is easy to feel smooth and can be cured after 2 doses of the medicine are taken continuously.

Case 4

Some morning, female, age 40, fever, pharyngalgia, pharynx itch, cough 4 days, pharyngalgia obvious swallowing, pharynx itch and adverse qi flow, cough, yellow and turbid phlegm, dry and bitter mouth, red tongue with yellow and greasy coating, and smooth and rapid pulse. Physical examination: the body temperature was 38.9 ℃, and the bilateral tonsils were enlarged II degrees and suppurative. And (3) Western diagnosis: suppurative tonsillitis. Traditional Chinese medicine syndrome differentiation: wind-heat affecting the lung. The method is to dispel wind, release exterior syndrome, clear heat and remove toxicity. By adopting the formula of the embodiment 2, the patient can obviously relieve the sore throat and fever and improve the cough after taking 1 dose of the medicine. After 4 doses, patients have no cough, no pharyngalgia, throat itching and normal body temperature.

Case 5

In the case of male, 39 years old, fever and aversion to cold after raining, 39.2 ℃, general soreness, hypodynamia, cough, yellow phlegm, thick phlegm, bitter taste and yellow urine. A red tongue with yellow coating and a slippery and rapid pulse. The treatment effect is poor when the medicine is taken by people for daily and night, such as Baifuning, amoxicillin capsules and the like. The syndrome differentiation of the traditional Chinese medicine is wind-heat type common cold. The method is to dispel wind, release exterior syndrome, clear heat and remove toxicity. The formulation of example 3 was used to cure the disease after 3 doses of the drug.

Claims (6)

1. The lung moistening medicine is characterized by comprising the following components in parts by mass: 20-30 parts of honeysuckle, 12-17 parts of selfheal, 15-20 parts of houttuynia cordata, 8-12 parts of kudzu root, 8-12 parts of dandelion, 6-12 parts of perilla fruit, 6-10 parts of chrysanthemum and 5-10 parts of liquorice.

2. The lung moistening medicine according to claim 1, which is characterized by comprising the following components in parts by mass: 25 parts of honeysuckle, 14 parts of selfheal, 17 parts of houttuynia cordata, 10 parts of kudzu root, 10 parts of dandelion, 9 parts of perilla fruit, 8 parts of chrysanthemum and 7 parts of liquorice.

3. The lung moistening medicine according to claim 1, which is characterized by comprising the following components in parts by mass: 30 parts of honeysuckle, 17 parts of selfheal, 20 parts of houttuynia cordata, 12 parts of kudzu root, 12 parts of dandelion, 12 parts of perilla fruit, 10 parts of chrysanthemum and 10 parts of liquorice.

4. The lung moistening medicine according to claim 1, which is characterized by comprising the following components in parts by mass: 20 parts of honeysuckle, 12 parts of selfheal, 15 parts of houttuynia cordata, 8 parts of kudzu root, 8 parts of dandelion, 6 parts of perilla fruit, 6 parts of chrysanthemum, 5 parts of liquorice and 3 parts of microcrystalline cellulose.

5. The preparation method of the lung moistening medicine is characterized by comprising the following steps:

a) weighing: weighing 10-15 parts of honeysuckle, 12-17 parts of selfheal, 15-20 parts of houttuynia cordata, 8-12 parts of kudzu vine root, 8-12 parts of dandelion, 6-12 parts of perilla fruit, 6-10 parts of chrysanthemum and 5-10 parts of liquorice;

b) respectively drying and crushing honeysuckle, selfheal, houttuynia cordata, kudzu vine root, dandelion, perilla fruit, chrysanthemum and liquorice to obtain powder of each component;

c) mixing the medicinal powder obtained in the step b) with water according to the weight ratio of 1: 0.6-0.95 to prepare a soft material;

d) preparing the soft material obtained in the step c) into wet granules, placing the wet granules into a centrifugal ball rolling machine for ball blasting, drying the prepared wet shot blasting at the temperature of 60-105 ℃, taking out, placing to room temperature, sieving, and taking out 10-24-mesh shot blasting.

6. The preparation method of the lung moistening medicine according to claim 5, wherein in the step d), the shot blasting process has the process parameters of a throwing rotation speed of 600-650 rpm and a throwing time of 15-20 min.