CN111227965B - 一种仿牙周膜牙种植体表面结构的设计与制造方法 - Google Patents

一种仿牙周膜牙种植体表面结构的设计与制造方法 Download PDF

Info

Publication number
CN111227965B
CN111227965B CN202010052031.7A CN202010052031A CN111227965B CN 111227965 B CN111227965 B CN 111227965B CN 202010052031 A CN202010052031 A CN 202010052031A CN 111227965 B CN111227965 B CN 111227965B
Authority
CN
China
Prior art keywords
dental implant
porosity
layer
pores
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202010052031.7A
Other languages
English (en)
Other versions
CN111227965A (zh
Inventor
孙玉春
张磊
周永胜
王勇
梁姗姗
原福松
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Peking University School of Stomatology
Original Assignee
Peking University School of Stomatology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peking University School of Stomatology filed Critical Peking University School of Stomatology
Priority to CN202010052031.7A priority Critical patent/CN111227965B/zh
Publication of CN111227965A publication Critical patent/CN111227965A/zh
Application granted granted Critical
Publication of CN111227965B publication Critical patent/CN111227965B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
    • B22F10/20—Direct sintering or melting
    • B22F10/28—Powder bed fusion, e.g. selective laser melting [SLM] or electron beam melting [EBM]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/48—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on zirconium or hafnium oxides, zirconates, zircon or hafnates
    • C04B35/486—Fine ceramics
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B38/00—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/65—Aspects relating to heat treatments of ceramic bodies such as green ceramics or pre-sintered ceramics, e.g. burning, sintering or melting processes
    • C04B2235/66—Specific sintering techniques, e.g. centrifugal sintering
    • C04B2235/665—Local sintering, e.g. laser sintering
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P10/00—Technologies related to metal processing
    • Y02P10/25—Process efficiency

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Structural Engineering (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Composite Materials (AREA)
  • Prostheses (AREA)

Abstract

本发明一种仿牙周膜牙种植体表面结构的设计与制造方法，有以下步骤：1)所述牙种植体分为2层，用3D打印软件生成打印文件；2)内层为实体结构，外层为从内向外孔隙率逐渐增大的梯度镂空结构；3)镂空结构的最内层孔隙率为0，最外层孔隙率为50‑80％；4)孔隙与隙间小梁形状为类骨小梁结构；5)用激光熔覆3D打印机打印成形；6)所用材料可为纯钛、钛合金、氧化锆或钛锆基非晶金属玻璃；8)消毒后能作为牙种植体产品使用。本发明能有效提升牙种植体表面的成骨性能，在一定程度上模仿牙周膜的力学缓冲效果，减少咀嚼功能状态下的局部应力集中，并可通过复杂的牙种植体的骨界面结构，显著降低牙种植体周围炎症的发生、进展，提高牙种植修复的远期成功率。

Description

一种仿牙周膜牙种植体表面结构的设计与制造方法
技术领域
本发明涉及一种口腔医用制品制作方法，具体涉及一种仿牙周膜牙种植体表面结构的设计与制造方法。
背景技术
现有的牙种植体表面结构非三维贯通结构，虽然能在牙种植体上使用，但主要问题在于：一是种植体表面结构为单一平直的界面，无贯通孔隙的表面骨结合面积相对较小，骨整合力不足，且无法有效阻断牙周细菌的快速侵入，不能降低种植体周围炎症的发生、进展；二是种植体材料与人体骨组织的弹性模量差异很大，易产生应力屏障，造成种植体-骨结合界面的应力集中，无法模拟天然牙齿牙周膜的缓冲性能。
发明内容
本发明的目的是提供一种仿牙周膜牙种植体表面结构的设计与制造方法，能有效提升牙种植体表面的成骨性能，在一定程度上模仿牙周膜的力学缓冲效果，减少咀嚼功能状态下的局部应力集中，并可通过复杂的牙种植体的骨界面结构，显著降低牙种植体周围炎症的发生、进展，提高牙种植修复的远期成功率。
为了达到上述目的，本发明有如下技术方案：
本发明的一种仿牙周膜牙种植体表面结构的设计与制造方法，有以下步骤：
1)所述牙种植体分为2层，用CAD软件设计并用3D打印软件生成打印文件；
2)内层为实体结构，外层厚度约0.1-0.5mm，为从内向外孔隙率逐渐增大的梯度
镂空结构；
3)镂空结构的最内层孔隙率为0，最外层孔隙率为50-80％；
4)孔隙与隙间小梁形状为类骨小梁结构，孔隙为圆柱形、圆锥形或圆台形，横截面直径约0.05-0.2mm；
5)用激光熔覆3D打印机打印成形；
6)所用材料可为纯钛、钛合金、氧化锆或钛锆基非晶金属玻璃；
8)消毒后能作为牙种植体产品使用。
其中，所述相邻孔隙之间三维贯通的孔隙，所述骨小梁结构为圆柱形状的单元结构交错堆积组成。
本发明的优点在于：能有效提升牙种植体表面的成骨性能，在一定程度上模仿牙周膜的力学缓冲效果，减少咀嚼功能状态下的局部应力集中，并可通过复杂的牙种植体的骨界面结构，显著降低牙种植体周围炎症的发生、进展，提高牙种植修复的远期成功率。
附图说明
图1是牙种植体表面结构的示意图；
图2是三维贯通孔隙的放大示意图。
图中，1、内层；2、外层；3、表面孔隙；4、三维贯通孔隙。
具体实施方式
以下实施例用于说明本发明，但不用来限制本发明的范围。
本发明的一种仿牙周膜牙种植体表面结构的设计与制造方法，有以下步骤：
1)所述牙种植体分为2层，用CAD软件设计并用3D打印软件生成打印文件；
2)内层为实体结构，外层厚度约0.1-0.5mm，为从内向外孔隙率逐渐增大的梯
度镂空结构；
3)镂空结构的最内层孔隙率为0，最外层孔隙率为50-80％；
4)孔隙与隙间小梁形状为类骨小梁结构，孔隙为圆柱形孔隙为圆柱形、圆锥形
或圆台形，横截面直径约0.05-0.2mm；
5)用激光熔覆3D打印机打印成形；
6)所用材料可为纯钛、钛合金、氧化锆或钛锆基非晶金属玻璃；
8)消毒后能作为牙种植体产品使用。
所述步骤2)外层是一层梯度过渡层，梯度体现于孔隙率和孔隙的大小变化，从内向外孔隙率和孔隙的直径越来越大；
所述相邻孔隙之间三维贯通的孔隙，所述骨小梁结构为圆柱形状的单元结构交错堆积组成。
本发明与现有的牙种植体的无贯通孔隙粗糙表面相比较，这种外层梯度渐变、且外层内部三维贯通的孔隙，可以让与成骨有关的细胞、因子根据其自身尺寸特点进入适合的空间定植；并且能在牙种植体和骨之间形成一层梯度过渡层，有利于应力缓冲，增强牙种植体与骨的结合力；同时，可大幅度倍增牙种植体与骨的结合面积。最后，可以在牙种植体长期使用过程中，通过复杂的结合界面，有效阻断牙周细菌的侵入和向根部快速感染。
3D打印机和3D打印机的软件，采用中国北京实诺泰克科技有限公司出品的口腔医用3D打印机和配套3D打印机的软件。
孔隙率：牙种植体表面孔隙层中，所有孔隙体积累加之和与孔隙层整体体积的比值。
如上所述，便可较为充分的实现本发明。以上所述仅为本发明的较为合理的实施实例，本发明的保护范围包括但并不局限于此，本领域的技术人员任何基于本发明技术方案上非实质性变性变更均包括在本发明包括范围之内。

Claims (2)

1.一种仿牙周膜牙种植体表面结构的设计与制造方法，其特征在于有以下步骤：
1)所述牙种植体分为2层，用CAD软件设计并用3D打印软件生成打印文件；
2)内层为实体结构，外层厚度0.1-0.5mm，为从内向外孔隙率逐渐增大的梯度镂空结构；
3)镂空结构的最内层孔隙率为0，最外层孔隙率为50-80％；
4)孔隙与隙间小梁形状为类骨小梁结构，孔隙为圆柱形、圆锥形或圆台形，横截面直径0.05-0.2mm；
5)用激光熔覆3D打印机打印成形；
6)所用材料为纯钛、钛合金、氧化锆或钛锆基非晶金属玻璃；
7)消毒后能作为牙种植体产品使用；
这种外层梯度渐变、且外层内部三维贯通的孔隙，能让与成骨有关的细胞、因子根据其自身尺寸特点进入适合的空间定植；并且能在牙种植体和骨之间形成一层梯度过渡层，有利于应力缓冲，增强牙种植体与骨的结合力；同时，能大幅度倍增牙种植体与骨的结合面积；最后，能在牙种植体长期使用过程中，通过复杂的结合界面，有效阻断牙周细菌的侵入和向根部快速感染；
所述步骤2)外层是一层梯度过渡层，梯度体现于孔隙率和孔隙的大小变化，从内向外孔隙率和孔隙的直径越来越大，孔隙形成锥形孔；
孔隙率：牙种植体表面孔隙层中，所有孔隙体积累加之和与孔隙层整体体积的比值。
2.根据权利要求1所述的一种仿牙周膜牙种植体表面结构的设计与制造方法，其特征在于：所述孔隙为三维贯通的孔隙，所述类骨小梁结构为圆柱形状的单元结构交错堆积组成。
CN202010052031.7A 2020-01-17 2020-01-17 一种仿牙周膜牙种植体表面结构的设计与制造方法 Active CN111227965B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010052031.7A CN111227965B (zh) 2020-01-17 2020-01-17 一种仿牙周膜牙种植体表面结构的设计与制造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010052031.7A CN111227965B (zh) 2020-01-17 2020-01-17 一种仿牙周膜牙种植体表面结构的设计与制造方法

Publications (2)

Publication Number Publication Date
CN111227965A CN111227965A (zh) 2020-06-05
CN111227965B true CN111227965B (zh) 2022-03-01

Family

ID=70870251

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010052031.7A Active CN111227965B (zh) 2020-01-17 2020-01-17 一种仿牙周膜牙种植体表面结构的设计与制造方法

Country Status (1)

Country Link
CN (1) CN111227965B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112754943A (zh) * 2020-12-30 2021-05-07 北京大学口腔医学院 仿生牙釉质氧化锆陶瓷材料块、牙修复体和制备方法
CN115089328B (zh) 2022-06-17 2023-05-12 汪晓晖 一种表面梯度微孔结构的牙种植体系统及其制备方法
CN115054388B (zh) * 2022-07-05 2024-04-02 北京大学口腔医学院 功能引导个性仿生多孔纯钽牙种植体及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904534A (en) * 1985-06-10 1990-02-27 Kureha Kagaku Kogyo Kabushiki Kaisha Implant material
CN102715960A (zh) * 2012-06-01 2012-10-10 上海交通大学 一种牙种植体及其制备方法
CN204293280U (zh) * 2014-10-30 2015-04-29 重庆润泽医药有限公司 一种种植牙钉
KR20160087707A (ko) * 2015-01-14 2016-07-22 오세만 3차원 스캔 데이터 추출을 위한 임플란트용 어버트먼트 및 이를 이용한 임플란트 시술방법
CN106037965A (zh) * 2016-08-23 2016-10-26 天津医科大学口腔医院 个体化仿生的牙种植体及其制作方法
CN106109032A (zh) * 2016-06-27 2016-11-16 西北有色金属研究院 一种梯度多孔结构牙种植体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107260342A (zh) * 2017-06-30 2017-10-20 青岛大学附属医院 一种3d打印仿生牙种植体及其制作方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904534A (en) * 1985-06-10 1990-02-27 Kureha Kagaku Kogyo Kabushiki Kaisha Implant material
CN102715960A (zh) * 2012-06-01 2012-10-10 上海交通大学 一种牙种植体及其制备方法
CN204293280U (zh) * 2014-10-30 2015-04-29 重庆润泽医药有限公司 一种种植牙钉
KR20160087707A (ko) * 2015-01-14 2016-07-22 오세만 3차원 스캔 데이터 추출을 위한 임플란트용 어버트먼트 및 이를 이용한 임플란트 시술방법
CN106109032A (zh) * 2016-06-27 2016-11-16 西北有色金属研究院 一种梯度多孔结构牙种植体
CN106037965A (zh) * 2016-08-23 2016-10-26 天津医科大学口腔医院 个体化仿生的牙种植体及其制作方法

Also Published As

Publication number Publication date
CN111227965A (zh) 2020-06-05

Similar Documents

Publication Publication Date Title
CN111227965B (zh) 一种仿牙周膜牙种植体表面结构的设计与制造方法
US11497583B2 (en) Methods of designing and manufacturing customized dental prosthesis for periodontal or osseointegration and related systems
US20170172712A1 (en) Customized Dental Prosthesis For Periodontal or Osseointegration and Related Systems
Mangano et al. Early human bone response to laser metal sintering surface topography: a histologic report
CN102715961A (zh) 个体化解剖型牙根种植体
CN103892930A (zh) 氧化锆陶瓷熔附生物活性玻璃陶瓷人工骨粉的牙种植体
CN202724012U (zh) 个体化解剖型牙根种植体
CN105232169A (zh) 多段式种植体组件及其制备方法
CN106859792B (zh) 多段式通孔多孔牙种植体
CN107374760A (zh) 一种具有药物携带功能的梯度多孔种植体
CN110742705B (zh) 一种填充可降解陶瓷多孔超短种植体及其制备方法
CN205569105U (zh) 一种复合义齿
CN107280789B (zh) 一种牙种植体
CN204233231U (zh) 人工牙根植体
CN111449777A (zh) 一种3d打印牙齿种植体及其制备方法与应用
CN208481503U (zh) 一种具有多段结构的3d打印牙根植入体
CN106510872A (zh) 一种支架下种植系统及其植入方法
CN203873903U (zh) 氧化锆陶瓷熔附生物活性玻璃陶瓷人工骨粉的牙种植体
CN206365939U (zh) 牙槽骨塑形器
CN210784768U (zh) 具有多孔结构的牙种植体
CN113749802A (zh) 一种载有施万细胞来源外泌体的改良多孔种植体
CN201701319U (zh) 一种口腔种植修复体
Liu et al. Design and additive manufacturing of root analogue dental implants: a comprehensive review
CN209996508U (zh) 一种个性化多孔层牙根种植体
CN111451508B (zh) 一种仿釉牙本质界的牙科修复体表面结构设计制作方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant