CN111214618A

CN111214618A - Freckle-removing traditional Chinese medicine composition and application thereof

Info

Publication number: CN111214618A
Application number: CN202010149220.6A
Authority: CN
Inventors: 于忠
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-03-06
Filing date: 2020-03-06
Publication date: 2020-06-02

Abstract

The invention provides a freckle-removing traditional Chinese medicine composition and application thereof. The freckle-removing traditional Chinese medicine composition comprises the following components in parts by weight: 1.5-2.5 parts of angelica, 1.5-2.5 parts of ginseng, 4.5-5.5 parts of Babaisan, 1.5-2.5 parts of astragalus, 0.5-1.5 parts of liquorice, 1.5-2.5 parts of rose, 0.5-1.5 parts of salvia miltiorrhiza and 4.5-5.5 parts of persimmon leaves. The freckle-removing traditional Chinese medicine composition can effectively aim at the freckles of different ages, different symptoms and different courses of disease, and has high cure rate and remarkable freckle-removing effect.

Description

Freckle-removing traditional Chinese medicine composition and application thereof

Technical Field

The invention relates to the technical field of freckle removal, and particularly relates to a freckle-removing traditional Chinese medicine composition and application thereof.

Background

Melanin is a protein in nature, which is present in the basal layer of the skin of everyone, and when ultraviolet rays are irradiated to the skin, the tyrosine in melanin is changed to become the activity of neuraminidase to protect the skin cells. The tyrosinase reacts with the leucine in the blood to generate a dopa substance, dopa is the precursor of melanin, and the leucine in the meridians is oxidized to release the melanin. Melanin in turn migrates to the surface layers of the skin via the layers of the metabolism. Beauty is the nature of human, various color spots such as freckles, chloasma, age spots and the like appear on the human face due to various reasons, the traditional Chinese medicine considers that the color spots are caused by common pigmentation dermatosis or capillary vessel blockage, and the traditional Chinese medicine considers that the color spots are removed and the pigmentation is eliminated due to deficiency of liver-kidney yin blood, unsmooth qi and blood and facial oxygen loss.

Chinese patent application with publication number CN 108553587A discloses a traditional Chinese medicine composition for whitening and removing freckles, which consists of 10 to 15 parts of ginseng, 10 to 15 parts of ligusticum wallichii, 10 to 15 parts of pyracantha fortuneana fruit, 15 to 30 parts of ampelopsis japonica, 15 to 30 parts of white muscardine silkworm, 15 to 30 parts of bletilla striata and 15 to 30 parts of cortex dictamni. When the whitening and freckle-removing traditional Chinese medicine composition is used for treatment, only 5 of 44 treatment groups are basically cured. Chinese patent application with publication number CN 108635489A discloses a freckle-removing traditional Chinese medicine composition, which is prepared from the following raw materials in parts by weight: 10-20 parts of radix rehmanniae, 10-20 parts of salvia miltiorrhiza, 10-20 parts of prepared rhizome of rehmannia, 5-20 parts of glossy privet fruit, 5-20 parts of polygonum multiflorum, 5-20 parts of white poria, 5-15 parts of eclipta alba, 5-15 parts of white paeony root, 5-15 parts of angelica, 5-15 parts of donkey-hide gelatin, 5-15 parts of medlar and 10-20 parts of Chinese yam. The freckle removing traditional Chinese medicine composition is used for treating 50 female chloasma patients, and only 21 female chloasma patients are basically cured. Therefore, most of the existing freckle-removing traditional Chinese medicine compositions have the defects of low cure rate and the like.

In view of this, the invention is particularly proposed.

Disclosure of Invention

The invention aims to provide a freckle-removing traditional Chinese medicine composition and application thereof, the freckle-removing traditional Chinese medicine composition can be used for removing freckles of different ages, different symptoms and different courses of disease, and has high cure rate and remarkable freckle-removing effect.

The invention provides a freckle-removing traditional Chinese medicine composition which comprises the following components in parts by weight: 1.5-2.5 parts of angelica, 1.5-2.5 parts of ginseng, 4.5-5.5 parts of Babaisan, 1.5-2.5 parts of astragalus, 0.5-1.5 parts of liquorice, 1.5-2.5 parts of rose, 0.5-1.5 parts of salvia miltiorrhiza and 4.5-5.5 parts of persimmon leaves.

Preferably, the freckle-removing traditional Chinese medicine composition comprises the following components in parts by weight: 2 parts of angelica sinensis, 2 parts of ginseng, 5 parts of babaosan, 2 parts of astragalus membranaceus, 1 part of liquorice, 2 parts of rose, 1 part of salvia miltiorrhiza and 5 parts of persimmon leaves.

The theory of traditional Chinese medicine considers that "the outer side with the interior and the minor with the left and the five internal organs with the twelve main meridians qi and blood flow ascending on the face". Chloasma is related to various factors of liver qi stagnation, blood stasis, liver and kidney deficiency, qi and blood deficiency, phlegm stagnation and the like of a human body. The pathogenesis of the liver-qi stagnation is caused by liver-qi stagnation, heat transformation over time and fumigation on the face, or the qi stagnation and blood stasis, nutrient-defense disharmony and obstruction of collaterals all occur on the face, or the liver and kidney deficiency impairs the Chong and ren disharmony, deficiency of essence and blood cannot nourish the face, or the spleen deficiency fails to strengthen the body and phlegm dampness is endogenous, and turbid pathogen stagnates on the face. In clinic, the treatment approaches of internal and external acupuncture and massage are mainly adopted, and the emphasis is on starting from the liver, spleen and kidney, correcting visceral dysfunction, and eliminating pathological factors such as qi stagnation, phlegm dampness and heat. The commonly used preparation methods comprise soothing liver and relieving qi stagnation, regulating qi and activating blood circulation, nourishing liver and kidney, soothing liver and strengthening spleen, warming yang and activating spleen, promoting diuresis and reducing phlegm, and removing dampness and heat.

The qi and blood theory of traditional Chinese medicine considers that the qi and blood circulation process is a material basis for all tissues and organs of a human body to work, the qi and blood are noble in smooth balance, if the qi and blood are smooth, blood stasis can be generated and blocked in the body, the qi and blood circulation can be further deteriorated, more serious congestion can be caused, and the ancient Chinese medicine takes the qi and blood as the principle, and can eliminate diseases, strengthen the body, nourish the blood and beautify the skin by regulating qi and activating blood to ensure smooth balance. The skin spots are basically stagnant, the skin spots are removed firstly when the worker is off duty, the stagnant needs to be treated as blood circulation, the blood circulation needs to tonify qi and regulate qi, qi is the commander of blood, the blood runs along with the blood, the blood keeps qi in place, the qi is quiet, the stagnation of qi is blood coagulation, the deficiency of qi is blood loss, and the qi is forced to remove the blood. Both qi and blood are harmonized. The qi is regulated in the liver, qi is supplemented in the lung and kidney, and the lung governs the skin and hair. The qi-blood circulation function of the lung, spleen, liver and kidney is affected by qi stagnation and blood stasis, so that chloasma, freckles and other stains appear on the face, and even alopecia areata occurs. The invention is mainly based on the principle of dialectical treatment of the traditional Chinese medicine, integrates peculiar drug secret recipes of the Bo-shou region, which is owned by the public and widely collected, extracts essences, is based on the understanding and treatment principle of the traditional Chinese medicine on the pathogenesis of facial color spots, refers to the pharmacological research achievements of the ancient and modern traditional Chinese medicines, screens natural traditional Chinese medicines for tonifying qi and activating blood, tonifying qi and invigorating yang, soothing liver and resolving depression, calming liver and suppressing yang, nourishing yin and tonifying kidney, clearing heat and removing toxicity, clearing heat and purging fire, strengthens body resistance and eliminating evil, purges and purges for toxin, activates blood circulation and removes stasis, regulates the metabolism function of a human body, improves the blood circulation and the liver detoxifying capability of the human body, and is summarized by the clinical practice.

The disease is called as 'blackish facial patch', 'liver patch', 'face dust' and the like in traditional Chinese medicine. The disease is caused by obvious endocrine, nervous system or digestive system dysfunction, and is influenced by a plurality of external physical and chemical factors such as sun exposure, heat radiation, trauma (scratching, rubbing and the like), exposure to photosensitive drugs or compounds, external silver preparations, mercury preparations and the like, so that the combination of internal and external treatment is generally claimed. And because the disease is located on the skin, the external treatment method becomes a key aspect in the treatment of the disease.

The freckle-removing traditional Chinese medicine composition has the following effects:

chinese angelica: it is sweet and heavy in flavor, so it can tonify blood, and its qi is light and pungent, so it can also invigorate blood, tonify the middle-jiao and move, and tonify qi in blood, also holy herbs in blood, so it can nourish nutrient, nourish blood, tonify qi and produce essence. To calm the five zang organs and strengthen the body and benefit the mind, it is not suitable for diseases with physical deficiency and can be used with the assistance of the other one to treat diseases with physical deficiency and deficiency syndrome, so it can relieve pain, relax bowels, activate tendons and bones, paralysis and dampness, etc., and it is weak in nutrient and exterior. For those who want to calm and avoid sexual slip, move and defecate insecurely, the actions of qi are pungent and motile, while those who want to calm and avoid yin-middle fire, the actions of Chinese angelica root and blood are not suitable, and those who are yin-middle yang deficient can nourish blood.

Ginseng: the ginseng is a traditional Chinese medicine for tonifying qi, is a representative of qi tonifying, can achieve the effects of tonifying qi, relieving collapse and rescuing from collapse by restoring yang with a single medicine, has the main effective component of ginsenoside in the ginseng, and has the effects of resisting oxidation, tumors, improving the immunity of the organism and the like at present, so the ginseng is a traditional Chinese medicine with stronger health-care effect, can enhance the excitability of cerebral cortex, improve the memory, enhance the anti-fatigue capability of a human body, also has the effects of resisting tumors, improving the immunity, resisting oxidation and the like, and is very helpful for protecting the cardiovascular and cerebrovascular vessels and preventing coronary heart disease and cerebrovascular disease.

BABAI SAN: the formula is as follows: clove, white muscardine silkworm, white pharbitis, tribulus terrestris, bletilla striata, angelica dahurica, rhizoma typhonii, white poria, Chinese honeylocust fruit, and mung bean. Wherein:

white clove: can remove freckle and wine thorn on noodles. Pungent flavor and warm nature. The white clove is the male sparrow feces. It can be used for treating facial sore and acne by soaking in honey, and has the effect of beautifying skin like jade.

White morning glory: the medicine is very smooth, and the effect of promoting flow of qi and blood is good for treating diseases caused by smooth qi and blood such as dark freckle or acne, and the diseases can be cured by self.

Tribulus terrestris: bitter and pungent in flavor and warm in nature. The compendium of materia Medica (Ben Cao gang mu) is characterized in that: wash face black, curt an, wash scar.

Bletilla striata: has the functions of nourishing skin, eliminating turbidity and stagnation, and treating dry skin ulcer on facial epithelium and smooth skin. Not only for dark field and dark face, but also for rhagadia manus et pedis, etc., it is a common medicine for ancient beauty treatment.

Radix angelicae: not only has fragrant smell, but also can promote skin growth and moisten color. In Benjing, it is said that it is used as face fat for nourishing and moistening skin. Radix Angelicae Dahuricae is the principal drug for preparing facial fat, whether from Qian jin Fang Lian Zhi or Yu Ling san.

Giant typhonium rhizome: the book Ben Cao Meng Jian (materia Medica Mongolia identification) is characterized in that: for treating various diseases on face, it can be used as face fat, smashed into fine powder, mixed with water, and applied to face for treating acne and freckle. It also has effects of perfuming body and eliminating scar and sore.

White poria: can eliminate black spot and acne. The book Ben Cao Pin Hui Jing Yao (materia Medica essence essences) says: the white poria is powder, mixed with honey, and applied on face to treat face sore and puerpera black purse such as sparrow egg. The white poria cocos can remove dark and white flour, can also fasten teeth and blacken hair, and can prolong life.

White atractylodes rhizome: can remove skin black spot, blackness, dizziness, acne and depressive psychosis. The Atractylodis rhizoma can be used for treating freckle and black speck by soaking in wine (vinegar) such as ink, and applying on face. The Sheng Yi Li Shizhen says that the side formulation treats the freckles 'extremely cause'.

Astragalus root: astragalus root, radix astragali, being mainly used for tonifying deficiency, can tonify qi, strengthen superficial resistance, induce diuresis, expel toxin, discharge pus, heal wound, promote the generation of tissue regeneration, and is indicated for qi and blood deficiency with ulceration and abscess, with pus failing to ulcerate or ulcerate for a long time. It has good toxin-expelling and vital-generating functions, and can promote the formation of abscess and tumor. Modern medical research shows that astragalus contains various antibacterial active ingredients, and the astragalus can enhance the immune function of organisms, so that astragalus can also be used for preventing certain infectious diseases. The herbal meet original Tibetan: astragalus root is a good medicine for reinforcing resistance and preventing diseases, which can tonify deficiency of five internal organs, treat wiry pulse spontaneous perspiration, purge yin fire to remove lung heat, and stop sweating if no sweating occurs.

Licorice root: clearing heat and removing toxicity: the liquorice can purge heart fire and has the functions of clearing heat and removing toxicity, modern medicine proves that the liquorice has better detoxifying function and can inhibit gastric acid secretion, and the liquorice has certain prevention and improvement effects on gastrointestinal tract ulcer disease after being eaten in a proper amount; the liquorice can tonify spleen and qi, is yellow and sweet in color and taste, has the effect of tonifying qi at atmospheric temperature, is a common medicine for tonifying spleen and qi, is often used together with spleen-tonifying and qi-tonifying medicines such as codonopsis pilosula, bighead atractylodes rhizome and the like, and is used for treating various qi deficiency syndromes, such as symptoms of heart qi deficiency, palpitation, weakness of spleen and stomach and the like; adjusting the drug property: the liquorice has unique sweet taste and has the function of relieving the properties of other medicines, so the liquorice can play a role of coordinating the properties and the tastes of other medicines when being commonly used in a compound prescription, and the liquorice can enable various medicines to be harmonious in various prescriptions, so the predecessor thinks that the liquorice can harmonize various medicines and is a medicine with different properties to be harmonious and play a role.

And (3) rose: sweet taste, slight bitter taste and warm nature, entering liver and stomach, recorded in Ben Cao gang mu Shi Yi: fragrant, warm in nature, sweet and slightly bitter in taste, enters spleen and liver meridians to regulate blood flow. Drug property (medicine): rose is warm in nature and has the actions of promoting blood circulation and removing blood stasis. "Renzhan of materia Medica" means: the rose flower is pungent and fragrant and can disperse and play roles in promoting qi circulation, resolving stagnation, removing blood stasis and removing ecchymoses.

Red sage root: is dried root and rhizome of Salvia miltiorrhiza Bunge of Labiatae. Collected in spring and autumn, removed of silt and dried. Most areas of the country have subdivisions. Has the effects of activating blood circulation to dissipate blood stasis, stimulating the menstrual flow to relieve pain, clearing away the heart-fire and relieving restlessness, cooling blood and eliminating carbuncle. Can be used for treating thoracic obstruction, heart pain, abdominal pain, hypochondriac pain, abdominal mass, paralysis pain, vexation, insomnia, menoxenia, dysmenorrhea, amenorrhea, and swelling and pain.

Persimmon leaf: the persimmon leaves contain a lot of tannic acid, which can play a role in sterilizing and relieving itching, and if people take the persimmon leaves for bathing, the persimmon leaves not only have the functions of cleaning and sterilizing the skin, but also can help to moisten the skin. The persimmon leaf also contains rich vitamins, has much higher content than that of a plurality of vegetables eaten by people in daily life, not only can diminish inflammation and invigorate blood circulation, but also has the effects of cancer prevention and cancer resistance, can be used for preparing drinks, can be prepared into food through corresponding conditioning, has good effects on human health care, particularly hypertension of the old, coronary heart disease and the like, and can promote human metabolism and dispel sub-health states.

The invention also provides application of the freckle-removing traditional Chinese medicine composition in preparing freckle-removing products.

The invention also provides a freckle removing composition, which comprises a first composition, a second composition and the freckle removing traditional Chinese medicine composition; wherein:

the first composition comprises the following components in parts by weight: 1.5-2.5 parts of vitamin C phosphate magnesium, 3.5-4.5 parts of EDTA (ethylene diamine tetraacetic acid), 1-2 parts of glycylglycine and 2.5-3.5 parts of arbutin;

the second composition comprises the following components in parts by weight: 0.5-1.5 parts of resveratrol, 1.5-2.5 parts of tea polyphenol, 1.5-2.5 parts of glutathione and 3.5-4.5 parts of sodium hyaluronate.

Preferably, the first composition comprises the following components in parts by weight: 2 parts of vitamin C phosphate magnesium, 4 parts of EDTA (ethylene diamine tetraacetic acid), 1.5 parts of glycylglycine and 3 parts of arbutin; the second composition comprises the following components in parts by weight: 1 part of resveratrol, 2 parts of tea polyphenol, 2 parts of glutathione and 4 parts of sodium hyaluronate.

The efficacy of each component in the first and second compositions is as follows:

vitamin C phosphate ester: has effects in inhibiting activity of tyrosinase, reducing melanin, removing speckle, whitening skin, and eliminating oxygen free radical after being administered into human body, thereby removing wrinkle, resisting aging, and has synergistic effect with vitamin E.

EDTA: EDTA is an important complexing agent. EDTA has a wide range of applications, and can be used as a bleaching fixing solution for processing a color photosensitive material, a dyeing auxiliary, a fiber treatment auxiliary, a cosmetic additive, a blood anticoagulant, a detergent, a stabilizer, a synthetic rubber polymerization initiator, and EDTA is a representative substance of a chelating agent. Can form stable water-soluble complex with alkali metal, rare earth element and transition metal.

D, phyllanthin: is an effective ingredient extracted from Phyllanthus emblica of Euphorbiaceae; the emblic leafflower fruit is sour and slightly astringent in taste, and has the effects of clearing heat, cooling blood, promoting digestion, tonifying spleen, promoting the production of body fluid and quenching thirst. It can be used for treating blood heat and blood stasis, dyspepsia, abdominal distention, cough, laryngalgia, xerostomia and vitamin C deficiency. In the Tibetan medicine, the emblic leafflower fruit is mainly used for treating bacon diseases, red bara diseases, blood diseases, hypertension and the like. The research results in recent years show that the emblic leafflower fruit has the effects of resisting inflammation, resisting oxidation, resisting aging, protecting the liver and the like. The emblic leafflower fruit contains various trace elements, is richer than the apple in content, and mainly contains selenium, zinc, calcium, phosphorus, iron, potassium and the like. The emblic leafflower fruit seed contains 26% of fatty acid and mainly comprises the following components: linolenic acid, linoleic acid, oleic acid, stearic acid, palmitic acid, myristic acid, and the like. The fructus Phyllanthi contains flavonoids; vitamin C, vitamin B1, vitamin B2, carotene, vitamin A, vitamin pp and the like, and particularly, the fruit vinegar is rich in vitamin C, the content of the vitamin C can reach 0.6% -0.92%, the content of the fruit in spring is the highest, sometimes even can reach 1.82%, the content of the vitamin C is 160 times of that of apples, and simultaneously is 100 times of that of oranges, and the fruit vinegar is only inferior to roxburgh roses of fruit vitamin C. The emblic leafflower fruit also contains 17 amino acids, including 8 amino acids required by human body, the total content of the amino acids reaches 185mg/100g, and the amino acids mainly comprise glutamic acid, proline, aspartic acid, alanine and lysine.

Arbutin: also called as arbutin, in the form of white needle crystals or powder. The extract is extracted from folium Vaccinii Vitis-idaeae, and has effects in inhibiting the activity of tyrosinase in vivo, preventing melanin generation, reducing skin pigmentation, removing mottle and freckle, killing bacteria, and relieving inflammation. Is mainly used for preparing high-grade cosmetics. The chemical formula of arbutin is C₁₂H₁₆O₇. The arbutin is a natural active substance derived from green plants, integrates the green plants, the safety and the reliability and the high-efficiency decoloration into a whole, can quickly permeate into the skin, can effectively inhibit the activity of the tyrosinase in the skin and block the formation of melanin while not influencing the cell proliferation concentration, accelerates the decomposition and excretion of the melanin by directly combining with the tyrosinase, thereby reducing the skin pigmentation, removing color spots and freckles, does not generate toxic, irritant, allergic and other side effects on the melanocytes, and also has the effects of sterilization and inflammation diminishing.

Resveratrol: is a non-flavonoid polyphenol compound, and is an antitoxin produced when many plants are stimulated. Can be synthesized in grape leaf and grape skin, and is bioactive component in wine and grape juice. It is easy to be absorbed by oral administration, and excreted via urine and feces after metabolism. In vitro experiments and animal experiments show that resveratrol has antioxidant, antiinflammatory, anticancer and cardiovascular protecting effects.

Tea polyphenol: it can effectively eliminate free radicals of human body, block lipid peroxidation process of human body, enhance activity of substances in human body, and effectively prevent cancer. Can accelerate the decomposition and metabolism of redundant fat of human body, reduce the deposition of cholesterol and triglyceride on the vessel wall, purify blood, soften blood vessel, and can effectively prevent hypertension, hyperlipemia and hyperglycemia by frequent administration. Improving immunity and enhancing disease resistance.

Sodium hyaluronate: the extract of rooster comb is white or white-like granule or powder obtained by fermentation of lactococcus lactis, has no odor, and has nitrogen content of 2.8-4.0% and glucuronic acid content of 37.0-51.0% in dry state. Is widely used in the field of cosmetics. The product is a physiologically active substance widely existing in animals and human bodies, and is distributed in human skin, synovial fluid of joints, umbilical cord, aqueous humor and vitreous humor. The molecular weight is 500000-730000 dalton, the solution has high viscoelasticity and imitability, and is used as adjuvant for ophthalmic surgery, and the medicinal liquid can be injected into anterior chamber to maintain certain anterior chamber depth, and is convenient for surgical operation, and has effects of protecting corneal endothelial cells and intraocular tissue, reducing surgical complications, and promoting wound healing.

Glutathione: widely exists in animals and plants, and plays an important role in organisms. The contents of yeast of bread, wheat germ and animal liver are very high, and excessive free radicals generated by organism metabolism can damage biological membranes, clear life macromolecules, accelerate the aging of organism and induce the occurrence of tumors or major arteriosclerosis. Glutathione plays an important role in the biochemical defense system of the human body and has various physiological functions, and the main physiological function of the glutathione is to remove free radicals in the human body, be used as an important antioxidant in the human body and protect the sulfydryl of molecules such as a plurality of proteins, enzymes and the like. The glutathione can not only remove free radicals of the human body, but also improve the immunity of the human body and maintain the health and resist aging. Plays an important role in the serious cells of the old. It also has a great effect on protecting the liver. Has strong protective effect on leucopenia caused by radioactive rays and radiopharmaceuticals.

The invention also provides application of the freckle removing composition in preparing freckle removing products.

The invention also provides a freckle-removing cream, which comprises a third composition, a fourth composition and the freckle-removing traditional Chinese medicine composition of claim 4 or 5; wherein:

the third composition comprises the following components in parts by weight: 3-5 parts of monoglyceride stearate, 8-12 parts of octadecanol, 6-8 parts of stearic acid, 1-2 parts of jojoba oil and 1-3 parts of dipotassium glycyrrhizinate;

the fourth composition comprises the following components in parts by weight: 10-12 parts of propylene glycol, 0.1-0.2 part of methylparaben, 802-3 parts of tween and 90-110 parts of deionized water.

Preferably, the third composition comprises the following components in parts by weight: 4 parts of monoglyceride stearate, 10 parts of octadecanol, 7 parts of stearic acid, 1.5 parts of jojoba oil and 2 parts of dipotassium glycyrrhizinate; the fourth composition comprises the following components in parts by weight: 11 parts of propylene glycol, 0.1 part of methylparaben, 802.2 parts of tween and 100 parts of deionized water.

The partial component efficacies of the third and fourth compositions are as follows:

jojoba oil: jojoba oil is a native plant in mexico, is planted globally, is most suitable for growth of the jojoba oil in the American-ink junction and Israel desert terrain, and has the best quality. The oil in the seed of the shrub plant with more than one person has good permeability and high temperature resistance. It can be used for various maintenance and treatment before 1000 years.

Dipotassium glycyrrhizinate: is white or quasi-white fine powder, has purity up to 98%, special sweet taste, good water solubility and pure taste. The dipotassium glycyrrhizinate has multiple effects of bacteriostasis, inflammation diminishing, detoxification, anti-allergy, deodorization and the like. Has wide application in the industries of medicine, cosmetics, daily chemicals, food and the like. Can be used in eye drop and stomatitis. Can activate corticosterone compound, can be used in all cosmetics such as ointment, cream, water, lotion, milk and honey, can neutralize or reduce toxic substances in cosmetics, can prevent anaphylactic reaction of some cosmetics, and is more suitable for advanced invention or cosmetics.

Furthermore, the freckle removing cream also comprises an additive, wherein the additive comprises 0.01-0.1 part of bronopol, and essence and the like.

The invention also provides a preparation method of the freckle removing cream, which comprises the following steps:

heating and stirring the third composition to 80-90 deg.C, heating and stirring the fourth composition to 40-50 deg.C, mixing and emulsifying to obtain a first mixture;

cooling the first mixture to 40-50 ℃, adding the first composition and the second composition, and stirring to obtain a second mixture;

adding the Chinese medicinal composition into the second mixture under slowly stirring and cooling to obtain freckle-removing cream.

The freckle-removing traditional Chinese medicine composition can be used for treating the freckles of different ages, different symptoms and different disease courses, the cure rate is up to more than 90%, and the freckle-removing effect is obvious.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

The embodiment provides a freckle-removing traditional Chinese medicine composition which comprises the following components in parts by weight: 2 parts of angelica sinensis, 2 parts of ginseng, 5 parts of babaosan, 2 parts of astragalus membranaceus, 1 part of liquorice, 2 parts of rose, 1 part of salvia miltiorrhiza and 5 parts of persimmon leaves.

Example 2

The embodiment provides a freckle removing composition, which comprises a first composition, a second composition and the freckle removing traditional Chinese medicine composition in the embodiment 1; specifically, the freckle removing composition of the embodiment comprises the following components in parts by weight:

the freckle-removing traditional Chinese medicine composition comprises the following components: 2 parts of angelica sinensis, 2 parts of ginseng, 5 parts of babaosan, 2 parts of astragalus membranaceus, 1 part of liquorice, 2 parts of rose, 1 part of salvia miltiorrhiza and 5 parts of persimmon leaves;

a first composition: 2 parts of vitamin C phosphate magnesium, 4 parts of EDTA (ethylene diamine tetraacetic acid), 1.5 parts of glycylglycine and 3 parts of arbutin;

a second composition: 1 part of resveratrol, 2 parts of tea polyphenol, 2 parts of glutathione and 4 parts of sodium hyaluronate.

Example 3

The embodiment provides a freckle removing cream which comprises a third composition, a fourth composition and the freckle removing composition of the embodiment 2; specifically, the freckle removing cream comprises the following components in parts by weight:

a second composition: 1 part of resveratrol, 2 parts of tea polyphenol, 2 parts of glutathione and 4 parts of sodium hyaluronate;

third composition: 4 parts of monoglyceride stearate, 1 part of octadecanol, 7 parts of stearic acid, 1.5 parts of jojoba oil and 2 parts of dipotassium glycyrrhizinate;

fourth composition: 11 parts of propylene glycol, 0.1 part of methylparaben, 802.2 parts of tween and 100 parts of deionized water;

additive: 0.05 part of Brobopol.

The preparation method of the freckle removing cream comprises the following steps:

accurately preparing the components according to the parts by weight;

mixing the components in the third composition, and heating and stirring to 85 ℃;

mixing the components of the fourth composition, and heating and stirring to 45 ℃;

mixing and emulsifying the heated and stirred third composition and the fourth composition to obtain a first mixture;

cooling the first mixture to about 45 ℃, adding the first composition and the second composition, and stirring to obtain a second mixture;

adding the freckle-removing traditional Chinese medicine composition into the second mixture under the conditions of slow stirring and cooling, and uniformly stirring to prepare a third mixture;

and adding the additive into the third mixture to prepare the freckle-removing cream.

Example 4

the freckle-removing traditional Chinese medicine composition comprises the following components: 2.5 parts of angelica, 1.5 parts of ginseng, 5.5 parts of Chinese magnoliavine root powder, 2.5 parts of astragalus, 0.5 part of liquorice, 2.5 parts of rose, 1.5 parts of salvia miltiorrhiza and 4.5 parts of persimmon leaves;

a first composition: 2.5 parts of vitamin C phosphate magnesium, 4.5 parts of EDTA (ethylene diamine tetraacetic acid), 1 part of glycylglycine and 2.5 parts of arbutin;

a second composition: 0.5 part of resveratrol, 2.5 parts of tea polyphenol, 1.5 parts of glutathione and 4.5 parts of sodium hyaluronate;

third composition: 3 parts of monoglyceride stearate, 2 parts of octadecanol, 6 parts of stearic acid, 2 parts of jojoba oil and 1 part of dipotassium glycyrrhizinate;

fourth composition: 10 parts of propylene glycol, 0.2 part of methylparaben, 802 parts of tween and 110 parts of deionized water.

Example 5

the freckle-removing traditional Chinese medicine composition comprises the following components: 1.5 parts of angelica, 2.5 parts of ginseng, 4.5 parts of Chinese magnoliavine root powder, 1.5 parts of astragalus, 1.5 parts of liquorice, 1.5 parts of rose, 0.5 part of salvia miltiorrhiza and 5.5 parts of persimmon leaves;

a first composition: 1.5 parts of vitamin C phosphate magnesium, 3.5 parts of EDTA (ethylene diamine tetraacetic acid), 2 parts of glycylglycine and 3.5 parts of arbutin;

a second composition: 1.5 parts of resveratrol, 1.5 parts of tea polyphenol, 2.5 parts of glutathione and 3.5 parts of sodium hyaluronate;

third composition: 5 parts of monoglyceride stearate, 1 part of octadecanol, 8 parts of stearic acid, 1 part of jojoba oil and 3 parts of dipotassium glycyrrhizinate;

fourth composition: 12 parts of propylene glycol, 0.1 part of methylparaben, 803 parts of tween and 90 parts of deionized water.

Test examples

The freckle removing cream in the embodiment 3 is adopted for testing, the number of clinical cases is 3980, and the using method is as follows: after face cleaning, the freckle-removing cream in the embodiment 3 is uniformly applied to the face once a day, and one month is a treatment course. The therapeutic criteria are as follows:

and (3) curing: the color spot disappeared and the face was smooth as before.

The method has the following advantages: the color spot is lightened, and the area is obviously reduced.

And (4) invalidation: the color spot disappeared less than one third.

The statistical data of the spot-removing curative effect clinical treatment of the spot-removing cream are shown in table 1.

TABLE 1 speckle-removing cream speckle-removing effect clinical treatment statistical data

Course of treatment	Number of examples	Cure of disease	Is effective	Invalidation
					1 course of treatment	540	420	107	13
2 courses of treatment	2680	2478	182	20
					3 courses of treatment	760	734	17	9

Table 1 the results show that: 3980 cases are treated in clinic, wherein the cure rate is as high as 90.5%, and the effective rate is 98.86%, so that the freckle removing traditional Chinese medicine composition can effectively treat the freckles of different ages, different symptoms and different courses of disease, and has high cure rate and remarkable freckle removing effect.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. The freckle-removing traditional Chinese medicine composition is characterized by comprising the following components in parts by weight: 1.5-2.5 parts of angelica, 1.5-2.5 parts of ginseng, 4.5-5.5 parts of Babaisan, 1.5-2.5 parts of astragalus, 0.5-1.5 parts of liquorice, 1.5-2.5 parts of rose, 0.5-1.5 parts of salvia miltiorrhiza and 4.5-5.5 parts of persimmon leaves.

2. The freckle-removing traditional Chinese medicine composition according to claim 1, which is characterized by comprising the following components in parts by weight: 2 parts of angelica sinensis, 2 parts of ginseng, 5 parts of babaosan, 2 parts of astragalus membranaceus, 1 part of liquorice, 2 parts of rose, 1 part of salvia miltiorrhiza and 5 parts of persimmon leaves.

3. The application of the freckle-removing traditional Chinese medicine composition according to claim 1 or 2 in preparing freckle-removing products.

4. A spot-removing composition, which is characterized by comprising a first composition, a second composition and the spot-removing traditional Chinese medicine composition of claim 1 or 2; wherein:

5. The spot removing composition according to claim 1, wherein the first composition comprises the following components in parts by weight: 2 parts of vitamin C phosphate magnesium, 4 parts of EDTA, 1.5 parts of glycylglycine and 3 parts of arbutin; the second composition comprises the following components in parts by weight: 1 part of resveratrol, 2 parts of tea polyphenol, 2 parts of glutathione and 4 parts of sodium hyaluronate.

6. Use of a speckle-removing composition according to claim 4 or 5 in the manufacture of a speckle-removing product.

7. A spot removing cream comprising a third composition, a fourth composition and the spot removing composition of claim 4 or 5; wherein:

the third composition comprises the following components in parts by weight: 3-5 parts of monoglyceride stearate, 1-2 parts of octadecanol, 6-8 parts of stearic acid, 1-2 parts of jojoba oil and 1-3 parts of dipotassium glycyrrhizinate;

8. The spot removing cream according to claim 7, wherein the third composition comprises the following components in parts by weight: 4 parts of monoglyceride stearate, 1 part of octadecanol, 7 parts of stearic acid, 1.5 parts of jojoba oil and 2 parts of dipotassium glycyrrhizinate; the fourth composition comprises the following components in parts by weight: 11 parts of propylene glycol, 0.1 part of methylparaben, 802.2 parts of tween and 100 parts of deionized water.

9. The spot removing cream of claim 7, further comprising an additive comprising 0.01-0.1 parts of bronopol.

10. A method of preparing a spot-removing cream according to any one of claims 7 to 9, comprising: