CN111166794A - A Chinese medicinal composition for treating gynecological diseases - Google Patents

A Chinese medicinal composition for treating gynecological diseases Download PDF

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CN111166794A
CN111166794A CN202010164582.2A CN202010164582A CN111166794A CN 111166794 A CN111166794 A CN 111166794A CN 202010164582 A CN202010164582 A CN 202010164582A CN 111166794 A CN111166794 A CN 111166794A
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姚同意
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/413Gall bladder; Bile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition for treating gynecological diseases, which comprises the following raw materials in parts by weight: 10-15 parts of raw pseudo-ginseng, 10-15 parts of raw rhubarb, 8-12 parts of raw coptis, 5-8 parts of pig gall and 3-5 parts of indigo naturalis. The invention takes pure natural traditional Chinese medicine raw materials as main active ingredients, the active ingredients of the medicinal materials supplement each other and mutually cooperate and enhance the function, thus being suitable for gynecological inflammation and stubborn diseases thereof and having obvious effect. The traditional Chinese medicine finished product is safe, has no stimulation to human bodies, has no side effect, is suitable for various cervical erosion and colpoxerosis of vaginitis, and has certain efficacy on vagina contraction.

Description

A Chinese medicinal composition for treating gynecological diseases
Technical Field
The invention relates to a traditional Chinese medicine composition for treating gynecological diseases, belonging to the technical field of gynecological medicines.
Background
Vaginitis (nonspecific, mycotic and trichomonas vaginitis) is a common gynecological disease. The common gynecological diseases mainly comprise trichomonas vaginitis, bacterial vaginitis and candida vaginitis, and the common diseases comprise the following common diseases: leukorrhagia, pruritus vulvae, burning sensation, menoxenia, dysmenorrhea, amenorrhea, etc. Clinically, the leucorrhea is the major symptom. The disease is more in spring and summer. Due to the action of inflammation, the lower abdomen often has the symptoms of dropping and swelling pain, scanty and unsmooth urine, sticky and thick leucorrhea which is not beneficial to the passing of sperms, and the sterility of women often results, and the physical and mental health of women is seriously affected. The prevention and treatment of such diseases has attracted high academic attention. At present, the western medicine mostly adopts medicines such as antibiotics and the like for systemic or local treatment, and the curative effect is definite. But because it is a chemical synthetic drug, it has certain toxic and side effects and adverse reactions. If the traditional Chinese medicine is improperly used, flora imbalance can be caused, and drug-resistant strains are formed, so that the condition of the patient is lingering and difficult to cure; and most of the chemicals have serious irritation to the skin due to the antibacterial components.
The existing traditional Chinese medicine preparation formulation for treating the vaginitis mainly comprises suppository, tablet and lotion, the suppository and the tablet are inconvenient to use, easily cause foreign body sensation in the vagina and easily damage the vagina, simultaneously the drug effect is exerted relatively slowly, and the suppository is dissolved to form liquid which flows out to pollute clothes; lotion is easier to flow out of vagina and pollute clothes, so the action time is short, and the medicine is difficult to release completely. In view of the above, the present invention aims to research a Chinese medicinal composition which has no side effect on patients, does not irritate skin, and has a good curative effect on gynecological diseases.
Disclosure of Invention
Aiming at the problems, the technical problem to be solved by the invention is to provide a traditional Chinese medicine composition for treating gynecological diseases.
In order to achieve the purpose, the invention provides the following technical scheme: a traditional Chinese medicine composition for treating gynecological diseases comprises the following raw materials in parts by weight: 10-15 parts of raw pseudo-ginseng, 10-15 parts of raw rhubarb, 8-12 parts of raw coptis, 5-8 parts of pig gall and 3-5 parts of indigo naturalis.
Further preferably, the traditional Chinese medicine composition for treating gynecological diseases comprises the following raw materials in parts by weight: 12 parts of raw pseudo-ginseng, 12 parts of raw rhubarb, 10 parts of raw coptis, 7 parts of pig gall and 4 parts of natural indigo.
A preparation method of a traditional Chinese medicine composition for treating gynecological diseases comprises the following steps: according to the weight part raw material ratio of the traditional Chinese medicine composition, raw pseudo-ginseng, raw rhubarb, raw coptis and natural indigo are cleaned, dried, crushed, added with 4-5 times of water for mixing, extracted for 3-4 times to obtain an extracting solution, and concentrated and dried to obtain dry powder;
step two, preparing the live pig gall into pig gall powder, wherein the specific preparation method comprises the following steps: cleaning the pig gall to remove impurities on the surface, then cutting the gall bladder of the pig gall, collecting the bile flowing out, and storing for later use; filtering the collected bile, pumping the filtered pig bile into a single-effect concentrator, carrying out reduced pressure heating concentration to obtain pig bile concentrated solution, pumping the pig bile concentrated solution into a spray dryer, carrying out spray drying, and filling into a plastic bag for later use after drying is finished to obtain pig bile powder;
and step three, mixing the dry powder prepared in the step one with the pig gall powder prepared in the step two.
When the traditional Chinese medicine composition is used, 2 g of the medicine powder is soaked in a small cotton ball, the small cotton ball is placed into the deep vagina of a patient and is kept for 48 hours, then the small cotton ball is taken out, the medicine composition is used by the same method every 36 hours, 5 times of the treatment course is one treatment course, the traditional Chinese medicine composition is suitable for various cervical erosion and vaginitis, and has certain efficacy on vaginal dryness and vaginal shrinkage.
Compared with the prior art, the invention has the following beneficial effects: the invention takes pure natural traditional Chinese medicine raw materials as main active ingredients, the active ingredients of the medicinal materials supplement each other and mutually cooperate and enhance the function, thus being suitable for gynecological inflammation and stubborn diseases thereof and having obvious effect. The traditional Chinese medicine finished product is safe, has no stimulation to human bodies, has no side effect, is suitable for various cervical erosion and colpoxerosis of vaginitis, and has certain efficacy on vagina contraction.
Detailed Description
The technical solutions of the present invention will be described clearly and completely in the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a traditional Chinese medicine composition for treating gynecological diseases comprises the following raw materials in parts by weight: 10 parts of raw pseudo-ginseng, 10 parts of raw rhubarb, 8 parts of raw coptis, 5 parts of pig gall and 3 parts of natural indigo.
The preparation method of the traditional Chinese medicine composition for treating gynecological diseases comprises the following steps: according to the weight part raw material ratio of the traditional Chinese medicine composition, 10 parts of raw pseudo-ginseng, 10 parts of raw rhubarb, 8 parts of raw coptis and 3 parts of natural indigo are cleaned, dried, crushed, added with 4-5 times of water for mixing, extracted for 3-4 times to obtain an extracting solution, and concentrated and dried to obtain dry powder;
step two, preparing the live pig gall into pig gall powder, wherein the specific preparation method comprises the following steps: cleaning 5 parts of pig gallbladder to remove impurities on the surface, cutting the gallbladder of the pig gallbladder, collecting the bile, and storing for later use; filtering the collected bile, pumping the filtered pig bile into a single-effect concentrator, carrying out reduced pressure heating concentration to obtain pig bile concentrated solution, pumping the pig bile concentrated solution into a spray dryer, carrying out spray drying, and filling into a plastic bag for later use after drying is finished to obtain pig bile powder;
and step three, mixing the dry powder prepared in the step one and the pig gall powder prepared in the step two into medicinal powder.
The use method of the traditional Chinese medicine composition comprises the following steps: when in use, 2 g of the medicinal powder is soaked in a small cotton ball, the medicinal powder is put into the deep vagina of a patient and kept for 48 hours, then the medicinal powder is taken out, the medicinal powder is used by the same method every 36 hours, and 5 times are taken as a treatment course.
Example 2:
a traditional Chinese medicine composition for treating gynecological diseases comprises the following raw materials in parts by weight: 15 parts of raw pseudo-ginseng, 15 parts of raw rhubarb, 12 parts of raw coptis, 8 parts of pig gall and 5 parts of indigo naturalis.
Example 2 the preparation method was the same as in example 1.
Example 3:
a traditional Chinese medicine composition for treating gynecological diseases comprises the following raw materials in parts by weight: 12 parts of raw pseudo-ginseng, 12 parts of raw rhubarb, 10 parts of raw coptis, 7 parts of pig gall and 4 parts of natural indigo.
Example 3 the preparation method was the same as in example 1.
The comparative example is a commercially available gel-type gynecological drug.
And (3) experimental verification: 400 women with gynecological diseases, wherein the women are 29-45 years old, married, non-menstrual period and gestational period, are randomly divided into 4 groups, 100 persons are in each group, 50 cases of nonspecific vaginitis in each group, 25 cases of trichomonas vaginitis and 25 cases of mycotic vaginitis, the gel type gynecological medicines provided by the examples 1-3 and the comparative example are continuously used for 20 days, and symptoms, signs and routine laboratory examination results of leucorrhea are recorded respectively before and after the application of the gel type gynecological medicines. The results are shown in Table 1.
TABLE 1
Figure BDA0002406963490000041
Therefore, the traditional Chinese medicine composition for treating the gynecological diseases has a remarkable curative effect and is suitable for various gynecological diseases.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (4)

1. A traditional Chinese medicine composition for treating gynecological diseases is characterized in that: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-15 parts of raw pseudo-ginseng, 10-15 parts of raw rhubarb, 8-12 parts of raw coptis, 5-8 parts of pig gall and 3-5 parts of indigo naturalis.
2. The traditional Chinese medicine composition for treating gynecological diseases according to claim 1, which is characterized in that: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 12 parts of raw pseudo-ginseng, 12 parts of raw rhubarb, 10 parts of raw coptis, 7 parts of pig gall and 4 parts of natural indigo.
3. A preparation method of a traditional Chinese medicine composition for treating gynecological diseases is characterized by comprising the following steps: the preparation method comprises the following steps: according to the weight part raw material ratio of the traditional Chinese medicine composition, raw pseudo-ginseng, raw rhubarb, raw coptis and natural indigo are cleaned, dried, crushed, added with 4-5 times of water for mixing, extracted for 3-4 times to obtain an extracting solution, and concentrated and dried to obtain dry powder;
step two, preparing the live pig gall into pig gall powder, wherein the specific preparation method comprises the following steps: cleaning the pig gall to remove impurities on the surface, then cutting the gall bladder of the pig gall, collecting the bile flowing out, and storing for later use; filtering the collected bile, pumping the filtered pig bile into a single-effect concentrator, carrying out reduced pressure heating concentration to obtain pig bile concentrated solution, pumping the pig bile concentrated solution into a spray dryer, carrying out spray drying, and filling into a plastic bag for later use after drying is finished to obtain pig bile powder;
and step three, mixing the dry powder prepared in the step one with the pig gall powder prepared in the step two.
4. A use method of a traditional Chinese medicine composition for treating gynecological diseases is characterized in that: when in use, 2 g of the medicinal powder is soaked in a small cotton ball, the medicinal powder is put into the deep vagina of a patient and kept for 48 hours, then the medicinal powder is taken out, the medicinal powder is used by the same method every 36 hours, and 5 times are taken as a treatment course.
CN202010164582.2A 2020-03-11 2020-03-11 A Chinese medicinal composition for treating gynecological diseases Pending CN111166794A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112206277A (en) * 2020-09-30 2021-01-12 夏文娟 Compound preparation for repairing vagina and cervical mucosa and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105560877A (en) * 2016-02-22 2016-05-11 常培兰 Traditional Chinese medicine composition for treating cervical disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105560877A (en) * 2016-02-22 2016-05-11 常培兰 Traditional Chinese medicine composition for treating cervical disease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
王宏伟;等: "猪胆汁大黄粉外用治疗外阴溃疡46例小结", 《甘肃中医》 *
黄国庆: ""百灵散"的临床运用", 《四川中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112206277A (en) * 2020-09-30 2021-01-12 夏文娟 Compound preparation for repairing vagina and cervical mucosa and preparation method thereof

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