CN111153382A - Hydrogen sustained release agent containing ammonia borane and application thereof - Google Patents

Hydrogen sustained release agent containing ammonia borane and application thereof Download PDF

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Publication number
CN111153382A
CN111153382A CN202010015597.2A CN202010015597A CN111153382A CN 111153382 A CN111153382 A CN 111153382A CN 202010015597 A CN202010015597 A CN 202010015597A CN 111153382 A CN111153382 A CN 111153382A
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hydrogen
release agent
ammonia borane
sustained release
magnesium
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邝允
孙晓明
李佳伟
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Beijing University of Chemical Technology
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Beijing University of Chemical Technology
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    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B3/00—Hydrogen; Gaseous mixtures containing hydrogen; Separation of hydrogen from mixtures containing it; Purification of hydrogen
    • C01B3/02—Production of hydrogen or of gaseous mixtures containing a substantial proportion of hydrogen
    • C01B3/06—Production of hydrogen or of gaseous mixtures containing a substantial proportion of hydrogen by reaction of inorganic compounds containing electro-positively bound hydrogen, e.g. water, acids, bases, ammonia, with inorganic reducing agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/45—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the shape
    • A61F13/49—Absorbent articles specially adapted to be worn around the waist, e.g. diapers
    • A61F13/496—Absorbent articles specially adapted to be worn around the waist, e.g. diapers in the form of pants or briefs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/84—Accessories, not otherwise provided for, for absorbent pads
    • A61F13/8405—Additives, e.g. for odour, disinfectant or pH control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B3/00—Hydrogen; Gaseous mixtures containing hydrogen; Separation of hydrogen from mixtures containing it; Purification of hydrogen
    • C01B3/02—Production of hydrogen or of gaseous mixtures containing a substantial proportion of hydrogen
    • C01B3/06—Production of hydrogen or of gaseous mixtures containing a substantial proportion of hydrogen by reaction of inorganic compounds containing electro-positively bound hydrogen, e.g. water, acids, bases, ammonia, with inorganic reducing agents
    • C01B3/065—Production of hydrogen or of gaseous mixtures containing a substantial proportion of hydrogen by reaction of inorganic compounds containing electro-positively bound hydrogen, e.g. water, acids, bases, ammonia, with inorganic reducing agents from a hydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/84—Accessories, not otherwise provided for, for absorbent pads
    • A61F13/8405—Additives, e.g. for odour, disinfectant or pH control
    • A61F2013/8408—Additives, e.g. for odour, disinfectant or pH control with odour control
    • A61F2013/8414—Additives, e.g. for odour, disinfectant or pH control with odour control with anti-microbic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30—Hydrogen technology
    • Y02E60/36—Hydrogen production from non-carbon containing sources, e.g. by water electrolysis

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  • Combustion & Propulsion (AREA)
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  • Medicinal Chemistry (AREA)
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Abstract

The invention belongs to the technical field of hydrogen production, and particularly relates to a hydrogen slow release agent containing ammonia borane and application thereof. The hydrogen slow release agent comprises the following components: ammonia borane, alkaline earth metal salt and drying agent. The invention also discloses the application of the hydrogen sustained release agent in paper diapers and daily health care. The invention innovatively utilizes the characteristic that ammonia borane is slowly hydrolyzed in water to release hydrogen for the first time, and obtains the hydrogen slow release agent capable of slowly releasing hydrogen by adding a plurality of specific components. The product belongs to a green pollution-free product which can quickly generate hydrogen-rich gas, has high safety and relatively low cost, is very easy to be applied to industrial expanded production, and particularly meets the requirement of modern people on daily health care by using hydrogen.

Description

Hydrogen sustained release agent containing ammonia borane and application thereof
Technical Field
The invention belongs to the technical field of hydrogen production, and particularly relates to a hydrogen slow release agent containing ammonia borane and application thereof.
Background
Hydrogen, as an inert gas with reducing properties, is almost ubiquitous in nature. The existing medicine shows that hydrogen can selectively remove hydroxyl free radicals, has stronger antioxidant effect, does not influence the functions of other active oxygen, and can improve on the aspect of energy metabolism, so that the hydrogen has good improvement and control effects on various pathological changes in vivo. In Japan, hydrogen has been added as an additive to foods, beauty masks, etc., and has effects of enhancing immunity, removing color spots, reducing weight, improving endocrine, etc. The hydrogen has no toxic or side effect on human bodies, and is widely suitable for various crowds. Therefore, the hydrogen-containing substance capable of slowly releasing hydrogen has a large market development space.
If a formula of the hydrogen slow-release agent which can be stable, safe and nontoxic for a long time can be provided, reductive hydrogen can be slowly released when the hydrogen slow-release agent needs to be used, and the hydrogen slow-release agent has important value.
Disclosure of Invention
The invention uses ammonia borane which is a substance with higher hydrogen storage value (up to 19.6wt percent of hydrogen storage capacity) for the first time to prepare the hydrogen slow release agent capable of slowly releasing hydrogen when in use. The theoretical basis of the invention is as follows: the ammonia borane is white solid at normal temperature and normal pressure, has a melting point of 104 ℃, is relatively stable and is convenient to store and transport. When ammonia borane is dissolved in water, hydrolysis reaction can be slowly carried out, and hydrogen is slowly released, so that a certain hydrogen concentration is always maintained in the solution.
The molecular formula of the ammonia borane is NH3·BH3Also known as borazane.
The invention provides a hydrogen slow release agent containing ammonia borane, which comprises the following components: ammonia borane, alkaline earth metal salt and drying agent.
Preferably, the desiccant is selected from at least one of calcium chloride, silica gel, molecular sieves, mineral desiccants, or fibrous desiccants. The drying agent can keep the hydrogen slow-release agent in a dry state and prevent the hydrogen from being released by moisture.
Preferably, the hydrogen slow release agent further comprises an adsorbent.
Preferably, the adding amount of the ammonia borane is 1-35% of the mass of the hydrogen slow release agent.
Preferably, the adsorbent is selected from one or more of attapulgite, kaolin, montmorillonite, talcum powder or sericite. The above are all natural minerals. The adsorbent can also be other substances with adsorbability: such as activated carbon.
The adsorbent has the following functions: the adsorbent has excellent adsorbability, and has a certain adsorption effect on substances such as peculiar smell and products obtained after ammonia borane hydrolysis; meanwhile, water can be stored, the continuous reaction in the ammonia borane hydrolysis process is ensured, and the hydrogen slow release agent is always in a reductive hydrogen-rich environment in a certain range.
Preferably, the alkaline earth metal salt is selected from at least one of calcium salt or magnesium salt, and the calcium salt or magnesium salt has a solubility in water of not less than 10g/100g water at 25 ℃.
Preferably, the alkaline earth metal salt is selected from at least one of calcium chloride, calcium nitrate, calcium bicarbonate, calcium dihydrogen phosphate, calcium acetate, calcium formate, magnesium chloride, magnesium nitrate, magnesium sulfate, magnesium acetate, magnesium formate, magnesium bicarbonate, or magnesium dihydrogen phosphate.
Preferably, the ratio of moles of the ammonia borane to moles of the alkaline earth metal salt is less than 2.
The metaborate ions after the ammonia borane hydrolysis are harmful to human bodies, so that the alkaline earth metal salts such as calcium chloride and magnesium chloride are added to precipitate the metaborate ions, and the harm of the metaborate ions in the solution can be removed.
Preferably, the hydrogen slow-release agent is in the form of powder, spheres, blocks or tablets.
Preferably, when the hydrogen slow release agent is in the form of powder, the particle size is not greater than 100 microns.
Preferably, when the hydrogen slow release agent is in a spherical shape, a block shape or a sheet shape, the inside is a mixture of the ammonia borane and the alkaline earth metal salt, and the outside coating layer is a mixture of an adsorbent and a drying agent.
Preferably, in the hydrogen slow release agent, by mass, the ammonia borane is 0.1-6 parts, the adsorbent is 80-95 parts, the desiccant is 6-20 parts, and the mole ratio of the ammonia borane to the alkaline earth metal salt is less than 2.
In a second aspect, the invention provides a use of the hydrogen sustained release agent of the first aspect in a diaper.
The panty-shape diapers can not in time be changed in the use for the panty-shape diapers breed the bacterium easily, if there is the wound in the panty-shape diapers package scope, probably aggravate the infection. When the product is added into the paper diaper, the paper diaper is soaked in use, and the hydrogen slow-release agent in the paper diaper can slowly release hydrogen, so that the range covered by the paper diaper is in a reductive hydrogen-rich environment, and the breeding of aerobic bacteria is inhibited.
In a third aspect, the invention provides the use of the hydrogen sustained release agent of the first aspect for daily health care.
The daily health care means that the hydrogen slow release agent can be added into daily necessities or daily chemicals for use, wherein the daily necessities or daily chemicals comprise, but are not limited to, washing or bathing products such as bath foam and facial cleanser, cosmetics, skin care products and the like.
The hydrogen slow release agent can also be added into daily chemicals such as facial masks. The hydrogen slow release agent is added when the mask is used, and the addition amount of the hydrogen slow release agent is 2 wt% of the mask base solution. This amount is reasonable and maintains the hydrogen concentration for a long period of time.
When used in daily chemical products such as facial masks, the paste facial mask can be prepared by adding one or more of natural mineral soils such as attapulgite, montmorillonite and kaolin, and adding glycerol, fish oil, skin care powder, etc. The mud-shaped mask has the function of skin water retention, can maintain hydrogen on the surface of skin for a longer time, and further improves the using curative effect of the product.
When the hydrogen slow-release agent is used in a bath, the hydrogen slow-release agent can be pressed into a spherical shape, a sheet shape or powder wrapped by powder, and is soaked in water when in use.
Preferably, when the hydrogen slow-release agent is a powder coated with a powder, the powder coating can coat the generated insoluble precipitate such as metaboric acid alkaline earth metal salt in the powder coating, and is permeable to air and water.
Preferably, the material of the powder bag is wrapped by conventional filter paper.
The hydrogen slow release agent needs to be sterilized by ultraviolet rays and needs to be stored in a dry and ventilated place.
The application schemes can be freely combined on the premise of no contradiction.
The invention has the following beneficial effects:
(1) currently, ammonia borane is mostly applied to the industrial field as a rocket high-energy fuel, and is not applied to the biochemical field by people. The invention innovatively utilizes the characteristic that ammonia borane can be slowly hydrolyzed to release hydrogen when meeting water for the first time, and obtains the hydrogen sustained-release agent capable of slowly releasing and controlling hydrogen by adding a plurality of specific components, belonging to a green pollution-free product rich in nano hydrogen, having high safety and relatively low cost, being easy for industrial production, and meeting the requirement of contemporary people on daily health care by using the hydrogen-rich product.
(2) The compatibility is high. The main auxiliary agents in the formula, such as alkaline earth metal salt, adsorptive clay, drying agent and the like, are common reagents for daily chemical products, have no problem of poor compatibility, and can be suitable for different cosmetic formulas comprising facial mask base solution.
(3) Has wide application. Uses of the hydrogen sustained release agent of the invention include, but are not limited to, applications in bath daily chemicals. When being used in the paper diaper, the hydrogen slow release agent can enable the paper diaper to be always in a hydrogen-rich reducing environment in the wrapping range, and bacteria are not easy to breed. When the hydrogen slow release agent is used in bath daily chemical products, the skin is in a hydrogen-rich state, and the released hydrogen can reduce active oxygen free radicals with high reactivity on the surface layer of the skin, so that oxidative damage and local inflammatory damage of the skin can be prevented.
(4) The hydrogen slow release agent slowly releases hydrogen for 36 hours when in use, and keeps the hydrogen concentration in the solution to be always more than 1400ppb, so the hydrogen slow release agent is always in the state of releasing hydrogen in the air and has higher stability.
Drawings
FIG. 1 is a graph showing the change in hydrogen concentration in the extruded solution when the diaper of example 1 is wetted with water for 0.5 to 36 hours.
FIG. 2 is a graph showing the change in hydrogen concentration of the hydrogen sustained release agent powder package of example 2 in water for 0.5 to 36 hours.
Detailed Description
The present invention will be further described with reference to the following embodiments.
The following experiments were all performed at room temperature of 25 ℃. The diapers used in the tests were commercially available.
Example 1
(1) Take 100g of hydrogen sustained release powder as an example. Taking 2g of ammonia borane, 69g of attapulgite, 8g of calcium chloride, 8g of magnesium chloride and 10g of silica gel to obtain a mixture.
(2) And (2) uniformly mixing and ball-milling the mixture obtained in the step (1), putting 10g of ball-milled powder into a filter paper powder bag, and sterilizing by ultraviolet rays for 10min to obtain a hydrogen sustained-release agent powder bag.
(3) And (3) placing the powder packet obtained in the step (2) into a paper diaper.
Preparing 7 same paper diapers containing the hydrogen slow-release agent powder bags, pouring 0.5L of water on each paper diaper, simulating the state of the paper diapers used by a person, sequentially waiting for 0.5, 3, 6, 9, 18, 24 and 36 hours, extruding the solution in the corresponding paper diapers, and testing the hydrogen concentration in the solution by using a hydrogen concentration test pen.
FIG. 1 is a graph showing the change in hydrogen concentration in the extruded solution when the diaper of example 1 is wetted with water for 0.5 to 36 hours.
As can be seen from fig. 1, the hydrogen concentration in the solution is always greater than 1400ppb, and the hydrogen sustained release agent will always be in a state of releasing hydrogen in the air due to the temperature of the use environment, which is approximately 37 degrees celsius of human body temperature. In addition, the posture of the human body is constantly changed during the use, and the hydrogen release rate of the hydrogen sustained release agent is accelerated.
Example 2
See the procedure in example 1, with the only differences: and (3) filling 5g of the ball-milled powder obtained in the step (2) into a filter paper powder bag, and sterilizing by ultraviolet rays for 10min to obtain a hydrogen sustained-release agent powder bag. The powder packet was then placed in 20ml of water to simulate the environment in which it was matched with a cosmetic mask base solution. The solution containing the hydrogen sustained release agent powder package is tested by a hydrogen test pen.
FIG. 2 is a graph showing the hydrogen concentration change of the hydrogen sustained release agent powder package of example 2 in water for 0.5 to 36 hours.
As can be seen from fig. 2, the hydrogen concentration in the solution was always greater than 1400 ppb. Therefore, the hydrogen eluting agent is always in a state of releasing hydrogen.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (10)

1. A hydrogen slow release agent containing ammonia borane is characterized in that the composition of the hydrogen slow release agent comprises: ammonia borane, alkaline earth metal salt and drying agent.
2. The hydrogen release formulation of claim 1, further comprising an adsorbent.
3. The hydrogen sustained release agent according to claim 1, wherein the amount of the ammonia borane added is 1 to 35 percent of the mass of the hydrogen sustained release agent.
4. The hydrogen releasing agent according to claim 1, wherein the adsorbent is one or more selected from the group consisting of attapulgite, kaolin, montmorillonite, talc, and sericite.
5. The hydrogen sustained release agent according to claim 1, wherein the alkaline earth metal salt is at least one selected from calcium salts and magnesium salts, and the calcium salts and magnesium salts have a solubility in water of not less than 10g/100g of water at 25 ℃.
6. The hydrogen sustained release agent according to claim 1, wherein the alkaline earth metal salt is at least one selected from the group consisting of calcium chloride, calcium nitrate, calcium hydrogen carbonate, calcium dihydrogen phosphate, calcium acetate, calcium formate, magnesium chloride, magnesium nitrate, magnesium sulfate, magnesium acetate, magnesium formate, magnesium hydrogen carbonate, and magnesium dihydrogen phosphate.
7. The hydrogen sustained release agent according to claim 1, wherein the ratio of the number of moles of the ammonia borane to the alkaline earth metal salt is less than 2.
8. The hydrogen sustained release agent according to claim 1, wherein the hydrogen sustained release agent is in the form of powder, sphere, block, or tablet.
9. Use of the hydrogen sustained-release agent according to claim 1 in a diaper.
10. Use of the hydrogen sustained release formulation of claim 1 for daily health care.
CN202010015597.2A 2020-01-07 2020-01-07 Hydrogen sustained release agent containing ammonia borane and application thereof Pending CN111153382A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113975401A (en) * 2021-09-29 2022-01-28 中国科学院深圳先进技术研究院 Medical hydrogen storage material and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
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CN101837953A (en) * 2010-05-12 2010-09-22 四川大学 Novel ammonia borane composite material for hydrolysis hydrogen production
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