CN111138525B - Antibody purification and recovery device and operation method - Google Patents
Antibody purification and recovery device and operation method Download PDFInfo
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- CN111138525B CN111138525B CN201911350161.2A CN201911350161A CN111138525B CN 111138525 B CN111138525 B CN 111138525B CN 201911350161 A CN201911350161 A CN 201911350161A CN 111138525 B CN111138525 B CN 111138525B
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- fixed ring
- circular arc
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- Genetics & Genomics (AREA)
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Abstract
The utility model provides an antibody purification recovery unit and operation method, includes curved pipe, standpipe, lower solid fixed ring, goes up solid fixed ring, mounting panel, locating plate, fastening circular arc board, the standpipe is connected on curved pipe upper portion, and the siphon inserts in standpipe, the curved pipe, and the recovery bottle is connected to the siphon outer end, the solid fixed ring down is connected in the curved pipe outside, gu fixed ring is connected in the standpipe outside, go up solid fixed ring is connected to solid fixed ring upside down, down solid fixed ring passes through the mounting axle and connects the mounting panel, the mounting panel inboard has the installation arch, and the installation arch is blocked respectively on solid fixed ring down, last solid fixed ring, mounting panel both sides pass through rotation axis connection fastening circular arc board, lower solid fixed ring, last solid fixed ring are connected to fastening circular arc inboard, fastening circular arc board card is on solid fixed ring down, last solid fixed ring, fastening circular arc board middle part has the fastening arch, and fastening arch is blocked respectively at down solid fixed ring.
Description
Technical Field
The invention relates to the field of antibody purification, in particular to an antibody purification and recovery device and an operation method.
Background
The antibody purification operation is completed by utilizing the cooperation of a curved pipe, a vertical pipe and the like, and solution recovery is completed by penetrating the siphon pipe into the vertical pipe and the curved pipe, however, the conventional antibody purification recovery device is inconvenient to operate, and inconvenience is brought to fixing between the curved pipe and the vertical pipe.
Disclosure of Invention
The invention provides an antibody purification and recovery device convenient to operate and an operation method thereof aiming at the defects in the prior art.
The invention aims at realizing the following technical scheme:
the utility model provides an antibody purification recovery unit, includes curved pipe, standpipe, lower solid fixed ring, goes up solid fixed ring, mounting panel, locating plate, fastening circular arc board, the standpipe is connected on curved pipe upper portion, and the siphon inserts standpipe, curved intraductal, and the recovery bottle is connected to the siphon outer end, gu the fixed ring down is connected in the curved pipe outside, gu the fixed ring is connected in the standpipe outside, gu the fixed ring is connected to fixed ring upside down, the fixed ring passes through the installation hub connection mounting panel down, the mounting panel inboard has the installation arch, and the installation arch is blocked respectively on fixed ring down, last fixed ring, the mounting panel both sides pass through rotation axis connection fastening circular arc board, solid fixed ring down is connected to fastening circular arc inboard, go up fixed ring down, fastening circular arc board card is on fixed ring down, last fixed ring, fastening circular arc board middle part has the fastening arch respectively the card down, go up fixed ring, the locating plate is connected to the locating plate left end, the locating plate lower part inlays on the fastening circular arc board.
The middle part of the positioning plate is provided with a positioning convex plate, two sides of the positioning convex plate are provided with positioning protrusions, the positioning protrusions are connected with the fastening circular arc plate, the positioning protrusions are clamped in the fastening circular arc plate, two sides of the positioning plate are provided with positioning convex rods, and the positioning convex rods are inserted into the fastening circular arc plate.
The beneficial effects are that:
the fastening bulges are respectively clamped on the lower fixing ring and the upper fixing ring, so that the connection and the positioning between the mounting plate and the lower fixing ring and between the mounting plate and the upper fixing ring are accurate, the connection and the positioning between the lower fixing ring and the upper fixing ring are accurate, convenience is brought to the connection between the lower fixing ring and the upper fixing ring, and the operation is simple and convenient. The fastening bulges are respectively clamped on the lower fixing ring and the upper fixing ring, so that the lower fixing ring and the upper fixing ring are relatively stable in structure, and the bent pipe and the vertical pipe are firmly connected. The positioning protrusions are clamped on the fastening circular arc plates, so that the position between the fastening circular arc plates at two sides is accurately positioned. The positioning convex rod is inserted into the fastening circular arc plate, so that the position of the fastening circular arc plate is limited, the fastening circular arc plates on two sides are tightly connected with the lower fixing ring and the upper fixing ring, and then the relative structures of the lower fixing ring, the upper fixing ring, the mounting plate and the fastening circular arc plate are stable, the relative structures of the curved pipe and the vertical pipe are stable, the relative positions among the curved pipe, the vertical pipe and the siphon pipe are determined, and the structure is reasonable.
Drawings
Fig. 1 is a schematic structural diagram of an antibody purification recovery apparatus according to the present invention.
Fig. 2 is a side view of fig. 1 according to the present invention.
FIG. 3 is a top cross-sectional view of an antibody purification and recovery apparatus according to the present invention.
Fig. 4 is an isometric view of a locating plate according to the present invention.
Detailed Description
The invention is described in further detail below with reference to the drawings and examples:
the utility model provides an antibody purification recovery unit, includes curved pipe 1, standpipe 2, lower solid fixed ring 3, goes up solid fixed ring 4, mounting panel 6, locating plate 9, fastening circular arc board 14, standpipe 2 is connected on curved pipe 1 upper portion, and the siphon inserts standpipe 2, in curved pipe 1, and the recovery bottle is connected to the siphon outer end, gu fixed ring 3 is connected down in curved pipe 1 outside, gu fixed ring 4 is connected in standpipe 2 outside, go up solid fixed ring 4 is connected to solid fixed ring 3 upside down, gu fixed ring 3 passes through mounting axle 5 and connects mounting panel 6 down, the mounting panel 6 inboard has installation arch 7, and the installation arch 7 is blocked respectively on solid fixed ring 3 down, go up solid fixed ring 4, the fastening circular arc board 14 is connected through axis of rotation 15 to mounting panel 6 both sides, gu fixed ring 3, go up solid fixed ring 4 down is connected to fastening circular arc board 14 inboard, gu fixed ring 3 is gone up solid fixed ring 4, gu the fastening circular arc board 14 middle part has fastening arch 13 block respectively on solid fixed ring 3 down, go up solid fixed ring 4, the left end connection locating plate 9, locating plate 9 inserts down in the locating plate.
The middle part of the locating plate 9 is provided with a locating convex plate 10, two sides of the locating convex plate 10 are provided with locating protrusions 11, the locating protrusions 11 are connected with a fastening circular arc plate 14, the locating protrusions 11 are clamped in the fastening circular arc plate 14, two sides of the locating plate 9 are provided with locating convex rods 12, and the locating convex rods 12 are inserted into the fastening circular arc plate 14.
The fastening bulges 13 are respectively clamped on the lower fixing ring 3 and the upper fixing ring 4, so that the connection and the positioning between the mounting plate 6 and the lower fixing ring 3 and the connection and the positioning between the mounting plate 6 and the upper fixing ring 4 are accurate, the connection and the positioning between the lower fixing ring 3 and the upper fixing ring 4 are accurate, convenience is brought to the connection between the lower fixing ring 3 and the upper fixing ring 4, and the operation is simple and convenient. The fastening bulges 13 are respectively clamped on the lower fixing ring 3 and the upper fixing ring 4, so that the lower fixing ring 3 and the upper fixing ring 4 have a stable relative structure, and the curved pipe 1 and the vertical pipe 2 are stably connected. The positioning protrusions 11 are clamped on the fastening circular arc plates 14, so that the position between the fastening circular arc plates 14 on two sides is accurately positioned. The positioning convex rod 12 is inserted into the fastening circular arc plate 14, so that the position of the fastening circular arc plate 14 is limited, the fastening circular arc plates 14 on two sides are tightly connected with the lower fixing ring 3 and the upper fixing ring 4, the lower fixing ring 3, the upper fixing ring 4, the mounting plate 6 and the fastening circular arc plate 14 are stable in relative structure, the curved pipe 1 and the vertical pipe 2 are stable in relative structure, the relative positions among the curved pipe 1, the vertical pipe 2 and the siphon are determined, and the structure is reasonable.
An operating method of an antibody purification recovery device, comprising the steps of:
the first step, connecting the bent pipe 1 and the vertical pipe 2 with each other, turning the mounting plate 6 upwards, and clamping the mounting bulges 7 on the lower fixing ring 3 and the upper fixing ring 4 respectively;
secondly, rotating the fastening circular arc plate 14, clamping the fastening circular arc plate 14 on the lower fixing ring 3 and the upper fixing ring 4, and respectively clamping the fastening protrusions 13 on the lower fixing ring 3 and the upper fixing ring 4;
thirdly, the positioning plate 9 is pushed downwards, the positioning convex plate 10 is clamped on the fastening circular arc plate 14, and then the positioning convex rod 12 is inserted into the fastening circular arc plate 14, so that the fixation is completed.
Claims (2)
1. The antibody purifying and recycling device is characterized by comprising a curved pipe, a vertical pipe, a lower fixed ring, an upper fixed ring, a mounting plate, a positioning plate and a fastening circular arc plate, wherein the upper part of the curved pipe is connected with the vertical pipe, the siphon is inserted into the vertical pipe and the curved pipe, the outer end of the siphon is connected with a recycling bottle, the outer side of the curved pipe is connected with the lower fixed ring, the outer side of the vertical pipe is connected with the upper fixed ring, the upper fixed ring is connected with the mounting plate through a mounting shaft, the inner side of the mounting plate is provided with a mounting bulge which is respectively clamped on the lower fixed ring and the upper fixed ring, two sides of the mounting plate are connected with the fastening circular arc plate through a rotating shaft, the inner side of the fastening circular arc plate is connected with the lower fixed ring and the upper fixed ring, the middle part of the fastening circular arc plate is provided with a fastening bulge, the fastening bulge is respectively clamped on the lower fixed ring and the upper fixed ring, the left end of the fastening circular arc plate is connected with the positioning plate, and the lower part of the positioning plate is embedded on the fastening circular arc plate; the middle part of the positioning plate is provided with a positioning convex plate, two sides of the positioning convex plate are provided with positioning protrusions, the positioning protrusions are connected with the fastening circular arc plate, the positioning protrusions are clamped in the fastening circular arc plate, two sides of the positioning plate are provided with positioning convex rods, and the positioning convex rods are inserted into the fastening circular arc plate.
2. The method for operating an antibody purification and recovery apparatus according to claim 1, comprising the steps of:
the first step, connecting the bent pipe and the vertical pipe with each other, turning the mounting plate upwards, and clamping the two mounting bulges on the lower fixing ring and the upper fixing ring respectively;
secondly, rotating the fastening circular arc plate, clamping the fastening circular arc plate on the lower fixing ring and the upper fixing ring, and respectively clamping the fastening bulges on the lower fixing ring and the upper fixing ring;
thirdly, pushing the positioning plate downwards, clamping the positioning convex plate on the fastening circular arc plate, and then inserting the positioning convex rod into the fastening circular arc plate to finish the fixation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911350161.2A CN111138525B (en) | 2019-12-24 | 2019-12-24 | Antibody purification and recovery device and operation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911350161.2A CN111138525B (en) | 2019-12-24 | 2019-12-24 | Antibody purification and recovery device and operation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111138525A CN111138525A (en) | 2020-05-12 |
| CN111138525B true CN111138525B (en) | 2023-04-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911350161.2A Active CN111138525B (en) | 2019-12-24 | 2019-12-24 | Antibody purification and recovery device and operation method |
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| Country | Link |
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| CN (1) | CN111138525B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009014590A (en) * | 2007-07-06 | 2009-01-22 | Koyo Sangyo Kk | Gas meter, and connecting structure for gas meter and gas pipe |
| JP2015086620A (en) * | 2013-10-31 | 2015-05-07 | シントク工業株式会社 | Relative rotation prevention structure |
| CN208362228U (en) * | 2018-05-29 | 2019-01-11 | 成都正能生物技术有限责任公司 | A kind of novel antibodies purification devices |
| CN209292266U (en) * | 2018-10-29 | 2019-08-23 | 武汉巴菲尔生物技术服务有限公司 | A kind of purification and recovery device of antibody |
| CN209385894U (en) * | 2018-12-26 | 2019-09-13 | 江苏亚光波纹管有限公司 | A kind of combined type elbow pressure balanced compensator |
-
2019
- 2019-12-24 CN CN201911350161.2A patent/CN111138525B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009014590A (en) * | 2007-07-06 | 2009-01-22 | Koyo Sangyo Kk | Gas meter, and connecting structure for gas meter and gas pipe |
| JP2015086620A (en) * | 2013-10-31 | 2015-05-07 | シントク工業株式会社 | Relative rotation prevention structure |
| CN208362228U (en) * | 2018-05-29 | 2019-01-11 | 成都正能生物技术有限责任公司 | A kind of novel antibodies purification devices |
| CN209292266U (en) * | 2018-10-29 | 2019-08-23 | 武汉巴菲尔生物技术服务有限公司 | A kind of purification and recovery device of antibody |
| CN209385894U (en) * | 2018-12-26 | 2019-09-13 | 江苏亚光波纹管有限公司 | A kind of combined type elbow pressure balanced compensator |
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| Publication number | Publication date |
|---|---|
| CN111138525A (en) | 2020-05-12 |
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Effective date of registration: 20230912 Address after: 300000 West of Lanjiazhuang Village, Dajianchang Town, Wuqing District, Tianjin City Patentee after: TIANJIN KANGERKE BIOSCIENCE Co.,Ltd. Address before: No. 2 Guotai Road, Dajianchang Town, Wuqing District, Tianjin, 300000 Patentee before: TIANJIN QITEER BIOTECHNOLOGY Co.,Ltd. |
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