CN111096981A - External-use medicine for treating various skin diseases and its preparing method - Google Patents
External-use medicine for treating various skin diseases and its preparing method Download PDFInfo
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- CN111096981A CN111096981A CN202010150158.2A CN202010150158A CN111096981A CN 111096981 A CN111096981 A CN 111096981A CN 202010150158 A CN202010150158 A CN 202010150158A CN 111096981 A CN111096981 A CN 111096981A
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- skin diseases
- realgar
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- 208000017520 skin disease Diseases 0.000 title claims abstract description 37
- 239000003814 drug Substances 0.000 title claims abstract description 28
- 238000000034 method Methods 0.000 title claims description 10
- 229910052957 realgar Inorganic materials 0.000 claims abstract description 17
- 239000002674 ointment Substances 0.000 claims abstract description 15
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 claims abstract description 13
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims abstract description 13
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims abstract description 13
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229930003471 Vitamin B2 Natural products 0.000 claims abstract description 13
- 239000004202 carbamide Substances 0.000 claims abstract description 13
- 238000001816 cooling Methods 0.000 claims abstract description 13
- 229960002477 riboflavin Drugs 0.000 claims abstract description 13
- 239000011716 vitamin B2 Substances 0.000 claims abstract description 13
- 235000019164 vitamin B2 Nutrition 0.000 claims abstract description 13
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 claims abstract description 11
- 235000001892 vitamin D2 Nutrition 0.000 claims abstract description 11
- 239000011653 vitamin D2 Substances 0.000 claims abstract description 11
- 238000002360 preparation method Methods 0.000 claims abstract description 10
- 229910021532 Calcite Inorganic materials 0.000 claims abstract description 7
- 238000003756 stirring Methods 0.000 claims abstract description 7
- 229910052956 cinnabar Inorganic materials 0.000 claims abstract description 6
- 241000402754 Erythranthe moschata Species 0.000 claims abstract description 5
- 229960003291 chlorphenamine Drugs 0.000 claims abstract description 5
- 238000004806 packaging method and process Methods 0.000 claims abstract description 4
- 238000003860 storage Methods 0.000 claims abstract description 4
- 241000972155 Moschus Species 0.000 claims abstract 4
- 238000000227 grinding Methods 0.000 claims description 6
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 5
- 238000004140 cleaning Methods 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 238000005360 mashing Methods 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 abstract description 4
- 230000003266 anti-allergic effect Effects 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 3
- 244000153234 Hibiscus abelmoschus Species 0.000 description 4
- 206010024229 Leprosy Diseases 0.000 description 2
- 241000234314 Zingiber Species 0.000 description 2
- 235000006886 Zingiber officinale Nutrition 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 235000008397 ginger Nutrition 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 206010052891 Skin bacterial infection Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000024386 fungal infectious disease Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/36—Arsenic; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Marine Sciences & Fisheries (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses an external medicine for treating various skin diseases and a preparation method thereof, wherein the external medicine for treating the skin diseases comprises the following components in parts by weight: 35g of calcite (prepared in a cooling mode), 10g of realgar, 5g of cinnabar, 5g of vermilion, 5g of abalone shell, 1g of musk, 10 tablets of vitamin B2, 40mg of chlorphenamine maleate and 50g of urea ointment, wherein during preparation, the realgar and the cinnabar are processed, crushed by a crusher and ground for later use; respectively stirring processed Mirabilitum crystallina (processed by cooling) 35g, Realgar 10g, Cinnabaris 5g, Vermilion 5g, Concha Haliotidis 5g, Moschus 1g, vitamin B2 tablet 10g, chlorphenamine 40mg, and urea ointment 50g, and standing; packaging the externally applied medicine for treating the skin diseases in the steps and placing the packaged externally applied medicine for treating the skin diseases in a refrigerated cabinet for storage; the external medicine for treating various skin diseases and the preparation method thereof have good curative effects on intractable skin diseases such as psoriasis and the like, have an anti-allergic effect, are suitable for old people and children, and can be popularized and used in a large range.
Description
Technical Field
The invention belongs to the field of pharmacy, and particularly relates to an external medicine for treating various skin diseases and a preparation method thereof.
Background
Skin disorders are a general term for disorders occurring in the skin and skin appendages. The skin is the largest organ of the human body, the skin diseases are not only various, but also diseases occurring in various internal organs can be shown on the skin. The skin diseases caused by various reasons, such as skin diseases caused by infection factors, such as leprosy, scabies, mycosis, skin bacterial infection and the like, have certain infectivity, not only affect the physical health, but also cause panic and social discrimination, but with the improvement of the living standard of people and the improvement of scientific and technological processes, the infectious diseases such as leprosy and the like are obviously controlled all over the world. Other internal and external factors causing skin diseases, such as mechanical, physical, chemical, biological, endocrine, immunity and the like, are more and more valued by people at present;
the existing externally applied medicine for treating the skin diseases can not well treat intractable skin diseases such as psoriasis and the like, has no antiallergic effect, and can not be well suitable for the old and children at the same time, so that the externally applied medicine for treating various skin diseases and the preparation method thereof are provided.
Disclosure of Invention
The invention mainly aims to provide an external medicine for treating various skin diseases and a preparation method thereof, which can effectively solve the problems in the background technology.
In order to achieve the purpose, the invention adopts the technical scheme that:
the externally applied medicine for treating various skin diseases comprises the following components in parts by weight: 35g of calcite (prepared by cooling), 10g of realgar, 5g of cinnabar, 5g of vermilion, 5g of abalone shell, 1g of musk, 10 vitamin B2 tablets, 40mg of chlorphenamine maleate tablets and 50g of urea ointment.
A preparation method of an external medicine for treating various skin diseases comprises the following steps:
s1: cleaning rhizoma Zingiberis recens, mashing to obtain juice, slightly adding clear water, adding Mirabilitum crystallina, decocting in a pot until the juice is dry, taking out, sun drying, and grinding;
s2: processing Realgar and Cinnabaris, pulverizing with pulverizer, and grinding;
s3: respectively stirring processed Mirabilitum crystallina (processed by cooling) 35g, Realgar 10g, Cinnabaris 5g, Vermilion 5g, Concha Haliotidis 5g, Moschus 1g, vitamin B2 tablet 10g, chlorphenamine 40mg, and urea ointment 50g, and standing;
s4: packaging the externally applied medicine for treating the skin diseases in the steps and placing the packaged externally applied medicine for treating the skin diseases in a refrigerated cabinet for storage.
Preferably, 10kg of ginger is used for every 100kg of calcite in the process of processing the calcite.
Preferably, Mirabilitum crystallina (processed by cooling), Realgar, Cinnabaris, Vermilion, Concha Haliotidis, Moschus, vitamin B2 tablet, chlorphenamine maleate tablet, and urea ointment are mixed for 5-6 min.
Preferably, Mirabilitum crystallina (processed by cooling), Realgar, Cinnabaris, Vermilion, Concha Haliotidis, Moschus, vitamin B2 tablet, chlorphenamine maleate tablet, and urea ointment by stirring and standing for 20-30 min.
Preferably, the temperature of the refrigerated cabinet is controlled at 2-8 ℃.
Compared with the prior art, the invention has the following beneficial effects: the external medicine for treating various skin diseases and the preparation method thereof have good curative effect on intractable skin diseases such as psoriasis and the like, have anti-allergic effect, are suitable for old people and children, and can be popularized and used in a large range.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
Example 1
The externally applied medicine for treating various skin diseases comprises the following components in parts by weight: 35g of calcite (prepared by cooling), 10g of realgar, 5g of cinnabar, 5g of vermilion, 5g of abalone shell, 1g of musk, 10 vitamin B2 tablets, 40mg of chlorphenamine maleate tablets and 50g of urea ointment;
the user is female, the age is 71 years old, and the psoriasis on the whole body can be cured for more than 10 years without relapse after being treated in 2006, 7 months by using the ointment.
Example 2
The externally applied medicine for treating various skin diseases comprises the following components in parts by weight: 35g of calcite (prepared by cooling), 10g of realgar, 5g of cinnabar, 5g of vermilion, 5g of abalone shell, 1g of musk, 10 vitamin B2 tablets, 40mg of chlorphenamine maleate tablets and 50g of urea ointment;
the user is male, the age is 55 years old, and the skin disease can be cured for many years by using the ointment.
Example 3
The preparation method comprises cleaning rhizoma Zingiberis recens, mashing to obtain juice, slightly adding clear water, adding Mirabilitum crystallina, decocting in a pot to dry, taking out, sun drying, and grinding; processing Realgar and Cinnabaris, pulverizing with pulverizer, and grinding; respectively stirring processed Mirabilitum crystallina (processed by cooling) 35g, Realgar 10g, Cinnabaris 5g, Vermilion 5g, Concha Haliotidis 5g, Moschus 1g, vitamin B2 tablets 10, chlorphenamine 40mg, and urea ointment 50g together, standing for 5-6min with ginger 10kg for each 100kg of Mirabilitum crystallina, and controlling the temperature of the refrigerator at 2-8 deg.C; packaging the externally applied medicine for treating the skin diseases in the steps and placing the packaged externally applied medicine for treating the skin diseases in a refrigerated cabinet for storage.
The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (6)
1. The externally applied medicine for treating various skin diseases is characterized by comprising the following components in parts by weight: 35g of calcite (prepared by cooling), 10g of realgar, 5g of cinnabar, 5g of vermilion, 5g of abalone shell, 1g of musk, 10 vitamin B2 tablets, 40mg of chlorphenamine maleate tablets and 50g of urea ointment.
2. The method for preparing an external medicine for treating various skin diseases as claimed in claim 1, wherein: the preparation method comprises the following steps:
s1: cleaning rhizoma Zingiberis recens, mashing to obtain juice, slightly adding clear water, adding Mirabilitum crystallina, decocting in a pot until the juice is dry, taking out, sun drying, and grinding;
s2: processing Realgar and Cinnabaris, pulverizing with pulverizer, and grinding;
s3: respectively stirring processed Mirabilitum crystallina (processed by cooling) 35g, Realgar 10g, Cinnabaris 5g, Vermilion 5g, Concha Haliotidis 5g, Moschus 1g, vitamin B2 tablet 10g, chlorphenamine 40mg, and urea ointment 50g, and standing;
s4: packaging the externally applied medicine for treating the skin diseases in the steps and placing the packaged externally applied medicine for treating the skin diseases in a refrigerated cabinet for storage.
3. The method for preparing an external medicine for treating various skin diseases as claimed in claim 2, wherein: in the process of processing Mirabilitum crystalline, 10kg of rhizoma Zingiberis recens is used for every 100kg of Mirabilitum crystalline.
4. The method for preparing an external medicine for treating various skin diseases as claimed in claim 2, wherein: mixing Mirabilitum crystallina (processed by cooling), Realgar, Cinnabaris, Vermilion, Concha Haliotidis, Moschus, vitamin B2 tablet, chlorphenamine maleate tablet, and urea ointment, and stirring for 5-6 min.
5. The method for preparing an external medicine for treating various skin diseases as claimed in claim 2, wherein: gypsum Fibrosum (processed by cooling), Realgar, Cinnabaris, Vermilion, Concha Haliotidis, Moschus, vitamin B2 tablet, chlorphenamine, and urea ointment by stirring and standing for 20-30 min.
6. The method for preparing an external medicine for treating various skin diseases as claimed in claim 2, wherein: the temperature of the refrigerated cabinet is controlled at 2-8 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010150158.2A CN111096981A (en) | 2020-03-02 | 2020-03-02 | External-use medicine for treating various skin diseases and its preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010150158.2A CN111096981A (en) | 2020-03-02 | 2020-03-02 | External-use medicine for treating various skin diseases and its preparing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111096981A true CN111096981A (en) | 2020-05-05 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010150158.2A Pending CN111096981A (en) | 2020-03-02 | 2020-03-02 | External-use medicine for treating various skin diseases and its preparing method |
Country Status (1)
| Country | Link |
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| CN (1) | CN111096981A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106668864A (en) * | 2016-10-19 | 2017-05-17 | 毕明华 | External-use ointment for treatment of dermatopathy |
-
2020
- 2020-03-02 CN CN202010150158.2A patent/CN111096981A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106668864A (en) * | 2016-10-19 | 2017-05-17 | 毕明华 | External-use ointment for treatment of dermatopathy |
Non-Patent Citations (1)
| Title |
|---|
| 齐国华: "嘎玛・珠尔新用", 医学文选, no. 04, 31 December 1991 (1991-12-31), pages 59 * |
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