CN111091302B - Nuclide drug order processing method and nuclide drug customization system - Google Patents
Nuclide drug order processing method and nuclide drug customization system Download PDFInfo
- Publication number
- CN111091302B CN111091302B CN201911337214.7A CN201911337214A CN111091302B CN 111091302 B CN111091302 B CN 111091302B CN 201911337214 A CN201911337214 A CN 201911337214A CN 111091302 B CN111091302 B CN 111091302B
- Authority
- CN
- China
- Prior art keywords
- nuclide
- drug
- information
- medicine
- demand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 349
- 229940079593 drug Drugs 0.000 title claims abstract description 194
- 238000003672 processing method Methods 0.000 title claims abstract description 15
- 238000012545 processing Methods 0.000 claims abstract description 11
- 230000000694 effects Effects 0.000 claims description 81
- 238000002360 preparation method Methods 0.000 claims description 57
- 238000000034 method Methods 0.000 claims description 47
- 238000004519 manufacturing process Methods 0.000 claims description 43
- 230000010365 information processing Effects 0.000 claims description 33
- 238000000605 extraction Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 238000007865 diluting Methods 0.000 description 6
- 238000009826 distribution Methods 0.000 description 6
- 238000012546 transfer Methods 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- 238000012790 confirmation Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000003113 dilution method Methods 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 229940121896 radiopharmaceutical Drugs 0.000 description 1
- 239000012217 radiopharmaceutical Substances 0.000 description 1
- 230000002799 radiopharmaceutical effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q10/00—Administration; Management
- G06Q10/06—Resources, workflows, human or project management; Enterprise or organisation planning; Enterprise or organisation modelling
- G06Q10/063—Operations research, analysis or management
- G06Q10/0631—Resource planning, allocation, distributing or scheduling for enterprises or organisations
- G06Q10/06315—Needs-based resource requirements planning or analysis
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q50/00—Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
- G06Q50/10—Services
- G06Q50/22—Social work or social welfare, e.g. community support activities or counselling services
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P90/00—Enabling technologies with a potential contribution to greenhouse gas [GHG] emissions mitigation
- Y02P90/30—Computing systems specially adapted for manufacturing
Landscapes
- Business, Economics & Management (AREA)
- Human Resources & Organizations (AREA)
- Engineering & Computer Science (AREA)
- Strategic Management (AREA)
- Tourism & Hospitality (AREA)
- Economics (AREA)
- Entrepreneurship & Innovation (AREA)
- Theoretical Computer Science (AREA)
- Physics & Mathematics (AREA)
- Marketing (AREA)
- General Physics & Mathematics (AREA)
- General Business, Economics & Management (AREA)
- Health & Medical Sciences (AREA)
- Educational Administration (AREA)
- Quality & Reliability (AREA)
- Operations Research (AREA)
- Game Theory and Decision Science (AREA)
- Development Economics (AREA)
- Child & Adolescent Psychology (AREA)
- General Health & Medical Sciences (AREA)
- Primary Health Care (AREA)
- Medical Treatment And Welfare Office Work (AREA)
Abstract
The invention relates to a nuclide medicine order processing method and a nuclide medicine customizing system, which are used for improving the efficiency of producing nuclide medicines according to hospital orders by pharmaceutical companies and processing orders and efficiency.
Description
Technical Field
The invention relates to the technical field of medicine customization, in particular to a nuclide medicine order processing method and a nuclide medicine customization system.
Background
Because of the commodity specificity of pharmaceutical commodities, particularly some very popular pharmaceutical commodities, generally require a throughput to be determined according to the amount required for use, so as to avoid the disappearance of the efficacy caused by the accumulation of pharmaceutical commodities and the long-term non-use of pharmaceutical commodities.
Radiopharmaceuticals are a typical and very commonly used pharmaceutical commodity, commonly referred to as nuclide drugs. The radioactivity of a nuclide drug is generally produced by an element in the drug, and a specified amount of radionuclide is added into the nuclide drug according to the requirement during production, and the radionuclide can be continuously decayed into isotopes with lower molar mass until the radioactivity is lost due to the natural property. Among these, the concentration of a given radionuclide in a nuclide drug is commonly referred to as activity.
The use of nuclide drugs is very strict, and a certain amount of nuclide drugs with certain activity are required to be used at a certain moment, and the activity of the nuclide drugs is continuously reduced once the nuclide drugs are produced, so that the nuclide drugs generally need to be customized by a hospital to a pharmaceutical company. The number of hospitals that single pharmaceutical company docks is more, and the quantity and the activity of the nuclide medicine that need in hospital are also various, and this can make pharmaceutical company receive huge, the various nuclide medicine orders of great variety, if can be to the order that pharmaceutical company received better processing, just can make things convenient for pharmaceutical company to produce the process of corresponding nuclide medicine according to the order.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a radioactive drug order information processing method, by adopting the method, a pharmaceutical company can conveniently classify and process complicated drug order information and process for producing nuclide drugs according to the drug order information, so that the pharmaceutical company can conveniently process the order information and efficiently produce nuclide drugs.
The above object of the present invention is achieved by the following technical solutions:
a nuclide drug order information processing method comprises the following steps:
collecting medicine requirement information of nuclide medicines; the medicine requirement information is as follows: hospital A x For the inclusion of nuclide P y The z-th requirement of nuclide drugs includes: time of demand T xyz Demand activity c xyz Demand volume V xyz The method comprises the steps of carrying out a first treatment on the surface of the Wherein x, y, z E n, n is a positive integer;
acquisition reference time T 0 According to nuclide P y Species-tuned species P of (2) y Decay curve L of (2) py According to the drug demand information and nuclide P y Decay curve L of (2) py Calculating drug production information; the drug production information is as follows: comprising a nuclide P y Nuclide drug at time of demand T xyz The activity is the required activity c xyz The volume is the required volume V xyz It is at the reference time T 0 The activity is the reference activity c xyz0 The volume is the reference volume V xyz0 The method comprises the steps of carrying out a first treatment on the surface of the Wherein the reference volume V xyz0 ≥V xyz ；
Collecting drug production information and generating drug preparation information according to the drug production information; the drug preparation information comprises nuclide P y Preparation activity c of nuclide drug y Preparation of volume V y, wherein ,cy ＝max(c xyz0 )，
Collecting production information and preparation information of a drug society, and generating drug proportioning information according to the production information and the preparation information of the drug; the medicine proportion information comprises the preparation activity of c y Comprises a nuclide P y The extraction ratio volume V 'of nuclide medicine' xyz And dilute it to the desired activity c xyz The volume is the required volume V xyz, wherein ,
by adopting the technical scheme, after a pharmaceutical company receives the medicine requirement information of each hospital for each nuclide medicine containing single nuclide, the reference activity and the reference volume of the nuclide medicine at the reference moment are reversely pushed according to the requirement activity and the decay curve of the appointed nuclide, then the preparation activity is determined according to the maximum reference activity of the nuclide medicine containing the same nuclide, the preparation volume is determined according to the preparation activity and the total quantity of the nuclides contained in the nuclide medicine, and the nuclide medicine containing the same nuclide is prepared together according to the preparation activity, so that the pharmaceutical company is convenient for the preparation process of the medicine, and the pharmaceutical company is convenient for purchasing nuclides according to the requirement; after the preparation of the nuclide medicine according to the preparation activity is completed, calculating a proportioning volume according to the reference activity, the reference volume and the preparation activity, and diluting the nuclide medicine with the proportioning volume to the reference volume, namely diluting the nuclide medicine with the preparation activity to the reference activity, so that the nuclide medicine with the reference activity and the reference volume at the reference moment is obtained; the nuclide medicine with the activity being the reference activity and the volume being the reference volume at the reference time, and the nuclide medicine with the required activity becomes the nuclide medicine with the required activity when naturally decaying to the required time so as to meet the requirements of hospitals; the method for preparing the nuclide drugs containing the same nuclide together and then diluting the nuclide drugs one by one to obtain the required activity and quantity of the nuclide drugs after the preparation facilitates the preparation of the nuclide drugs by pharmaceutical companies, improves the efficiency of preparing the corresponding nuclide drugs according to orders by the pharmaceutical companies, and improves the processing speed of the pharmaceutical companies on the orders.
Further, the reference volume V xyz0 ≤1.2V xyz 。
By adopting the technical scheme, in the process of transferring the nuclide medicine, the nuclide medicine is wasted when being transferred from one container to the other container, and the reference volume is larger than the required volume, so that the problem that the quantity of the nuclide medicine caused by the waste cannot meet the requirement of the required volume due to the waste in the transfer process is avoided; the reference volume is smaller than 1.2 times of the required volume, so that the waste caused by natural invalidation of the nuclide medicine due to excessive preparation of the nuclide medicine which is not needed to be used and the overlarge reference volume is avoided.
Further, if p, q is e n and p < q, if x, z is e [ p, q]When it contains the same species of nuclide P y Reference activity c xyz0 Are equal, then the same nuclide P is contained in the proportioning step y Reference activity c xyz0 The same nuclide drugs are diluted together, namely the similar volume with the same proportion is needed to be taken outPreparation activity c of (2) y The nuclide medicine of (1) is similar to the volume of the same proportionThen the similar mixture ratio volume is->
Through adopting above-mentioned technical scheme, in the nuclide medicine that contains same nuclide, with consulting the same nuclide medicine of activity together dilute, dilute the back and go to the volume division according to the needs of corresponding reference volume again, made things convenient for the process of diluting, improved the efficiency of dilution, also made the nuclide medicine in the dilution process can pass through less container transfer, reduced the extravagant of nuclide medicine in the circulation process.
Further, the reference time T 0 And the time of demand T xyz Time interval deltat between xyz ≤24h。
By adopting the technical scheme, the reference time is generally the time when the production of the nuclide drug is finished and the nuclide drug can be delivered to a hospital, the time interval between the reference time and the demand time is less than 24 hours, and the loss of the nuclide drug caused by long natural decay of the nuclide drug due to overlong time interval between the production completion and the delivery of the nuclide drug to the hospital is avoided.
Further, the preparation of the nuclide drug is completedAfter that, hospital A x Is counted in hospital A x Statistics under statistics sub-directory of drug demand information includes nuclide P y Drug demand information of nuclide drugs.
Through adopting above-mentioned technical scheme, after nuclide medicine ratio is accomplished, firstly classify nuclide medicine according to hospital's name, classify the nuclide medicine that contains different nuclides to single hospital again to make things convenient for the hospital to confirm and receive nuclide medicine, made things convenient for pharmaceutical company's distribution process, reduced the extravagant time in pharmaceutical company's distribution process.
Another object of the present invention is to provide a nuclide drug ordering system by which a hospital orders drugs and a pharmaceutical company can conveniently process order information and efficiently produce nuclide drugs when the pharmaceutical company produces nuclide drugs through the system.
The above object of the present invention is achieved by the following technical solutions:
a nuclide drug ordering system, comprising:
the medicine requirement acquisition terminal is used for acquiring the medicine requirement information;
and the demand information processing platform is used for processing the medicine demand information according to the nuclide medicine order information processing method and generating the medicine production information, the medicine preparation information and the medicine proportioning information.
Through adopting above-mentioned technical scheme, the hospital obtains terminal input medicine demand information through the medicine demand in order to pharmaceutical company, demand information processing platform is according to medicine demand information and above-mentioned medicine order information processing method to the processing of medicine order information, generate medicine production information, medicine preparation information and medicine ratio information, pharmaceutical company is according to medicine production information, medicine demand information and medicine ratio information carry out the nuclide and purchase, nuclide medicine preparation and nuclide medicine ratio, can make things convenient for pharmaceutical company to produce the process of nuclide medicine according to order information, practice thrift pharmaceutical company's time of handling medicine order information, improve pharmaceutical company's efficiency according to medicine order information production nuclide medicine greatly.
Further, the demand information processing platform classifies and stores the medicine demand information, the medicine production information, the medicine preparation information and the medicine proportioning information according to the date.
By adopting the technical scheme, the classified storage mode of the medicine demand information, the medicine production information, the medicine preparation information and the medicine proportioning information according to the date is convenient for the pharmaceutical company to inquire the data according to the date.
Further, the demand information processing platform classifies and stores the medicine demand information, the medicine production information, the medicine preparation information and the medicine proportioning information according to the hospital name.
By adopting the technical scheme, the classified storage mode of the medicine demand information, the medicine production information, the medicine preparation information and the medicine proportioning information according to the hospital name is convenient for a pharmaceutical company to inquire the data according to the hospital name.
Further, the demand information processing platform is further used for acquiring the drug price information of the nuclide drug so as to output drug payment order information according to the drug demand information and the drug price information; the payment order information includes at least a payment amount.
Through adopting above-mentioned technical scheme, pharmaceutical company inputs the medicine price information that contains the real-time price of nuclide medicine through the demand information processing platform, and the hospital is after obtaining terminal input medicine demand information through the medicine demand, and demand information processing platform can automatic generation corresponding payment order information, and the hospital directly pays corresponding amount to pharmaceutical company through payment order information to pharmaceutical company's amount transaction process has been made things convenient for pharmaceutical company and hospital.
Further, the requirement information acquisition platform also generates medicine label information according to the medicine requirement information, medicine production information, medicine preparation information and medicine proportioning information; the drug label information includes a species of the nuclear drug contained in the nuclear drug and/or a reference activity at a reference time and/or a demand activity at a demand time and/or a reference volume and/or a demand volume.
By adopting the technical scheme, the pharmaceutical company gives corresponding nuclide medicines according to the medicine label information and gives the medicine label information, so that the identification and confirmation of the pharmaceutical company and hospitals on the nuclide medicines are facilitated, the time consumed in the nuclide medicine logistics process is reduced, the possibility of errors in the nuclide medicine logistics process is reduced, and the distribution efficiency of the pharmaceutical company on the nuclide medicines is also improved.
In summary, the present invention includes at least one of the following beneficial technical effects: the nuclide medicine order processing method and the nuclide medicine ordering system are convenient for pharmaceutical companies to classify complicated medicine order information and to carry out the process of producing nuclide medicines according to the medicine order information, so that the pharmaceutical companies can conveniently and efficiently process the order information and produce nuclide medicines.
Drawings
FIG. 1 is a flow chart of a method according to a first embodiment of the invention;
fig. 2 is a schematic diagram of a system structure according to a second embodiment of the present invention.
In the figure, 1, a medicine requirement activity terminal; 2. and (5) requiring an information processing platform.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings.
Embodiment one:
referring to fig. 1, a nuclide drug order information processing method includes the following steps performed in sequence:
s1, collecting medicine requirement information of nuclide medicines; the medicine requirement information is as follows: hospital A x For the inclusion of nuclide P y The z-th requirement of nuclide drugs includes: time of demand T xyz Demand activity c xyz Demand volume V xyz The method comprises the steps of carrying out a first treatment on the surface of the Wherein x, y, z E n, n is a positive integer; wherein, hospital A x Representing different hospital names, nuclide P y Representing different nuclide species contained in nuclide drugs, the time of demand T xyz Demand activity c xyz Volume of demand V xyz Indicating that the hospital is on a nuclide drug containing the nuclideA need. Collecting medicine requirement information of nuclide medicines; the medicine requirement information is as follows: hospital A x For the inclusion of nuclide P y The z-th requirement of nuclide drugs includes: time of demand T xyz Demand activity c xyz Demand volume V xyz The method comprises the steps of carrying out a first treatment on the surface of the Wherein x, y, z E n, n is a positive integer; wherein, hospital A x Representing different hospital names, nuclide P y Representing different nuclide species contained in nuclide drugs, the time of demand T xyz Demand activity c xyz Volume of demand V xyz Represents a need for a nuclide drug containing the nuclide for the hospital.
S2, collecting reference time T 0 According to nuclide P y Species-tuned species P of (2) y Decay curve L of (2) py According to the drug demand information and nuclide P y Decay curve L of (2) py Calculating drug production information; the drug production information is as follows: comprising a nuclide P y Nuclide drug at time of demand T xyz The activity is the required activity c xyz The volume is the required volume V xyz It is at the reference time T 0 The activity is the reference activity c xyz0 The volume is the reference volume V xyz0 The method comprises the steps of carrying out a first treatment on the surface of the Wherein the reference volume V xyz0 ≥V xyz The method comprises the steps of carrying out a first treatment on the surface of the Wherein the reference volume V xyz ≤V xyz0 ≤1.2V xyz Reference time T 0 And the time of demand T xyz Time interval deltat between xyz Less than or equal to 24 hours, in this embodiment preferably V xyz0 ＝1.1V xyz . The basic principle of the step is to push nuclide drugs with different demand moments to a reference moment by utilizing the natural law of nuclide decay, so that pharmaceutical companies can prepare nuclide drugs uniformly.
Setting the reference volume to 1.1 times the required volume mainly considers that the residual volume of the nuclide drug is reduced during the transfer process, such as when transferring from one container to another container, so that a certain margin is set to avoid that the required volume of the hospital cannot be met after the nuclide drug is reduced, and of course, the loss during the nuclide drug transfer process is limited, if the margin is too large, the nuclide drug is causedAfter the use, more residue still exists, and the inventor experiences that the residue is set to be 0.1V xyz The method is more suitable, and the allowance can not only meet the loss requirement in the nuclide drug circulation process, but also avoid excessive residue after the nuclide drug is used.
The time interval between the reference time and the demand time is set to be less than 24 hours, and the corresponding nuclide medicine is generally produced on the day of the demand time, wherein the time interval is used for a pharmaceutical company to produce, package, deliver and distribute the nuclide medicine, if the time interval is too short, the pharmaceutical company can not complete the production, packaging, delivering and delivering of the nuclide medicine on time, and if the time interval is too long, the nuclide medicine can lose a large amount of activity due to natural decay. Likewise, setting the time interval to be within 24 hours is a suitable time interval determined according to the experience of the inventor.
S3, acquiring drug production information and generating drug preparation information according to the drug production information; the drug preparation information comprises nuclide P y Preparation activity c of nuclide drug y Preparation of volume V y, wherein ,cy ＝max(c xyz0 )，The basic principle of the step is as follows: for the nuclide drugs containing the same nuclides, the total content of nuclides in the nuclide drugs with the prepared activities and the prepared volumes is equal to the sum of corresponding products of the reference activities and the reference volumes, namely the total amount of nuclides of the same nuclides is constant; the preparation volume can be accurately controlled by calculating the preparation volume, so that the prepared nuclide drug can just meet the requirement of the reference moment.
S4, collecting production information and preparation information of a drug society, and generating drug proportioning information according to the production information and the preparation information of the drug; the medicine proportion information comprises the preparation activity of c y Comprises a nuclide P y The extraction ratio volume V 'of nuclide medicine' xyz And dilute it to the desired activity c xyz The volume is the required volume V xyz, wherein ,For the nuclide drugs containing the same nuclide, since the preparation activity is the maximum reference activity, other smaller reference activities need to be obtained by diluting the nuclide drug with the preparation activity, the volume of the nuclide drug with the preparation activity needed by the nuclide drug with the reference time and the reference volume is fixed, and the dilution method for diluting the nuclide drug with higher activity and the nuclide drug to the nuclide drug with lower activity is a conventional technical means for those skilled in the art and is not described herein.
In S4, the reference activities of the nuclide drugs containing the same kind of nuclides are probably the same, the nuclide drugs with the same kind of nuclides and the same reference activity are proportioned together, and then the proportioned nuclide drugs are divided, so that the drug proportioning process is convenient, the frequency of transferring the nuclide drugs between different containers can be reduced, and the possibility of wasting the nuclide drugs in the transferring process is reduced. Specifically, if p, q εn and p < q, if x, z εp, q]When it contains the same species of nuclide P y Reference activity c xyz0 Are equal, then the same nuclide P is contained in the proportioning step y Reference activity c xyz0 The same nuclide drugs are diluted together, namely the similar volume with the same proportion is needed to be taken outPreparation activity c of (2) y The nuclide medicine of (2) is similar to the matching volume +.>Then the similar mixture ratio volume is->Divided into reference volumes V xyz0 。
S5, hospital A x Is counted in hospital A x Statistics under statistics sub-directory of drug demand information includes nuclide P y Drug demand information of nuclide drugs. The nuclide drugs are classified according to hospital names, and then the nuclide drugs are packaged for a single hospitalThe nuclide drugs containing different nuclides are classified, so that the confirmation and the reception of the nuclide drugs by hospitals are facilitated, the distribution process of pharmaceutical companies is facilitated, and the waste time in the distribution process of the pharmaceutical companies is reduced.
In the specific application process, when the method is used for processing the medicine demand information, firstly, the demand time, the demand activity, the nuclide medicine containing nuclide types and the demand volume are all different, the nuclide medicine is reversely pushed to the reference time according to the decay curve of the corresponding nuclide, the reference activity and the reference volume are calculated, and the process of delivering the nuclide and preparing and proportioning the nuclide medicine is carried out according to the reference activity and the reference volume, so that the production process of the nuclide medicine by pharmaceutical companies is facilitated, and the processing speed of the pharmaceutical companies on orders is improved.
Embodiment two:
referring to fig. 2, a nuclide drug ordering system includes a drug demand acquisition terminal for use by a hospital and a demand information processing platform 2 for use by a pharmaceutical company.
The medicine requirement acquisition terminal is used for acquiring the medicine requirement information in the first embodiment, and the medicine requirement acquisition terminal comprises a plurality of medicine requirement acquisition terminals for a plurality of customers of a pharmaceutical company, namely different hospitals. The requirement information processing platform 2 is in wireless communication connection with a drug requirement acquisition terminal, and in this embodiment, a 4G network is preferable. The requirement information processing platform 2 is used by pharmaceutical companies, and the requirement information processing platform 2 can process the medicine requirement information according to the nuclide medicine order information processing method in the first embodiment to generate medicine production information, medicine preparation information and medicine proportioning information in the first embodiment.
The requirement information processing platform 2 can also be used for classifying and storing the medicine requirement information, the medicine production information, the medicine preparation information and the medicine proportioning information according to dates, hospital names and nuclide types contained in nuclide medicines respectively, so that a pharmaceutical company can conveniently inquire appointed data according to requirements.
The demand information processing platform 2 can also generate medicine label information according to the medicine demand information, medicine production information, medicine preparation information and medicine proportioning information, the medicine label information comprises the kind of nuclide contained in nuclide medicine, the reference activity at the reference moment, the demand activity at the demand moment, the reference volume and the demand volume, and a pharmaceutical company is used for pasting labels containing appointed medicine label information on the packages of corresponding nuclide medicines after completing nuclide medicine production and packaging, so that the information of the nuclide medicines is clearly visible, thereby facilitating the identification and confirmation of the nuclide medicines by the pharmaceutical company and hospitals, reducing the time consumed in the nuclide medicine logistics process, reducing the possibility of errors in the nuclide medicine logistics process, and improving the distribution efficiency of the pharmaceutical company on the nuclide medicines.
The demand information processing platform 2 is further configured to obtain drug price information of a nuclide drug, the demand information processing platform 2 outputs drug payment order information according to the drug price information and the drug demand information, wherein the drug price information is a real-time price of the nuclide drug, a payment amount required to be paid by a hospital for customizing the nuclide drug is calculated according to a type and a volume of the nuclide drug required by the drug demand information, the drug payment order information comprises the payment amount required to be paid, it is understood that the drug demand acquisition terminal can be associated with an online banking account of the hospital through a setting of the hospital, the demand information processing platform 2 can be associated with an official account of the pharmaceutical company through a setting of the pharmaceutical company, and an amount transaction process of the hospital and the pharmaceutical company can be facilitated through cooperation of the drug demand acquisition terminal and the demand information processing platform 2.
Furthermore, the demand information processing platform 2 can also record the above-mentioned money transaction process, so that the pharmaceutical company can check the transaction records, and the transaction records can also be classified and stored in a manner of classifying according to date, hospital name and nuclide type contained in nuclide medicine, so that the pharmaceutical company can inquire the specified data according to the demand.
The specific application process comprises the following steps: the nuclide drug ordering system has the advantages that the nuclide drug ordering information processing method in the first embodiment is applied, and has all the beneficial effects of the nuclide drug ordering information processing method in the first embodiment; namely, the method and the system can also facilitate the classification processing of complicated medicine order information by pharmaceutical companies and the production process of nuclide medicines according to the medicine order information, thereby facilitating the efficient processing of the order information and the efficient production of nuclide medicines by the pharmaceutical companies, which are both the preferred embodiments of the invention, and are not used for limiting the protection scope of the invention, so that the method and the system can be used for effectively processing the order information and the efficient production of nuclide medicines: all equivalent changes in structure, shape and principle of the invention should be covered in the scope of protection of the invention.
Claims (6)
1. The nuclide medicine order information processing method is characterized by comprising the following steps:
collecting medicine requirement information of nuclide medicines; the medicine requirement information is as follows: hospital A x For the inclusion of nuclide P y The z-th requirement of nuclide drugs includes: time of demand T xyz Demand activity c xyz Demand volume V xyz The method comprises the steps of carrying out a first treatment on the surface of the Wherein x, y, z E n, n is a positive integer;
acquisition reference time T 0 According to nuclide P y Species-tuned species P y Decay curve L of (2) py According to the drug demand information and nuclide P y Decay curve L of (2) py Calculating drug production information; the drug production information is as follows: comprising a nuclide P y Nuclide drug at time of demand T xyz The activity is the required activity c xyz The volume is the required volume V xyz It is at the reference time T 0 The activity is the reference activity c xyz0 The volume is the reference volume V xyz0 The method comprises the steps of carrying out a first treatment on the surface of the Wherein the reference volume V xyz0 ≥V xyz ；
Collecting drug production information and generating drug preparation information according to the drug production information; the drug preparation information comprises nuclide P y Preparation activity c of nuclide drug y Preparation of volume V y, wherein ,cy ＝max(c xyz0 )，
Collecting production information of a drug society and preparation information of the drug,generating drug proportioning information according to the drug production information and the drug preparation information; the medicine proportion information comprises the preparation activity of c y Comprises a nuclide P y The extraction ratio volume V 'of nuclide medicine' xyz And dilute it to the desired activity c xyz The volume is the required volume V xyz ，
wherein ,
the reference volume V xyz0 ≤1.2V xyz ；
If p, q.epsilon.n and p < q, if x, z.epsilon.p, q]When it contains the same species of nuclide P y Reference activity c xyz0 Are equal, then the same nuclide P is contained in the proportioning step y Reference activity c xyz0 The same nuclide drugs are diluted together, namely the similar volume with the same proportion is needed to be taken outPreparation activity c of (2) y The nuclide medicine of (1) is similar to the volume of the same proportionThen the similar mixture ratio volume is->Divided into reference volumes V xyz0 ；
The reference time T 0 And the time of demand T xyz Time interval deltat between xyz ≤24h；
After the nuclide medicine proportioning is completed, hospital A is carried out x Is counted in hospital A x Statistics under statistics sub-directory of drug demand information includes nuclide P y Drug demand information of nuclide drugs.
2. A nuclide drug ordering system, comprising:
a medicine requirement acquisition terminal for acquiring the medicine requirement information of any one of claims 1;
the requirement information processing platform is used for processing the medicine requirement information by the nuclide medicine order information processing method according to any one of the claim 1 to generate medicine production information, medicine preparation information and medicine proportioning information according to any one of the claim 1.
3. The nuclide drug ordering system of claim 2, wherein the demand information processing platform sorts and stores the drug demand information, the drug production information, the drug preparation information, and the drug proportioning information by date.
4. The nuclide drug ordering system of claim 2, wherein the demand information processing platform sorts and stores the drug demand information, the drug production information, the drug preparation information, and the drug proportioning information by hospital names.
5. The nuclide drug ordering system of claim 2, wherein the demand information processing platform is further configured to obtain drug price information for a nuclide drug to output drug payment order information based on the drug demand information and drug price information; the payment order information includes at least a payment amount.
6. The nuclide drug ordering system of claim 2, wherein the demand information acquisition platform further generates drug label information based on the drug demand information, drug production information, drug preparation information, and drug proportioning information; the drug label information includes a species of the nuclear drug contained in the nuclear drug and/or a reference activity at a reference time and/or a demand activity at a demand time and/or a reference volume and/or a demand volume.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911337214.7A CN111091302B (en) | 2019-12-23 | 2019-12-23 | Nuclide drug order processing method and nuclide drug customization system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911337214.7A CN111091302B (en) | 2019-12-23 | 2019-12-23 | Nuclide drug order processing method and nuclide drug customization system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111091302A CN111091302A (en) | 2020-05-01 |
| CN111091302B true CN111091302B (en) | 2023-08-15 |
Family
ID=70395304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911337214.7A Active CN111091302B (en) | 2019-12-23 | 2019-12-23 | Nuclide drug order processing method and nuclide drug customization system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111091302B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001172204A (en) * | 1999-12-16 | 2001-06-26 | Hitachi Ltd | Method of making and selling examination chemical, installation for making and selling examination chemical, method for feeding examination chemical and supplying system therefor |
| CN103837880A (en) * | 2012-11-27 | 2014-06-04 | 周荣 | Method for correcting radionuclide activity measurement |
| CN104318393A (en) * | 2014-10-27 | 2015-01-28 | 北京智博高科生物技术有限公司 | Radiopharmaceutical production management system |
| CN104484793A (en) * | 2014-12-02 | 2015-04-01 | 北京智博高科生物技术有限公司 | Dynamic calibration system for radiopharmaceutical radionuclide activity |
| CN107462915A (en) * | 2017-04-07 | 2017-12-12 | 中国人民解放军北京军区疾病预防控制中心 | A kind of real-time measuring method of radiopharmaceutical activity and system |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010017605A2 (en) * | 2008-08-15 | 2010-02-18 | Caetano Norival | Method of standardization of injectable medicines and their diluents |
-
2019
- 2019-12-23 CN CN201911337214.7A patent/CN111091302B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001172204A (en) * | 1999-12-16 | 2001-06-26 | Hitachi Ltd | Method of making and selling examination chemical, installation for making and selling examination chemical, method for feeding examination chemical and supplying system therefor |
| CN103837880A (en) * | 2012-11-27 | 2014-06-04 | 周荣 | Method for correcting radionuclide activity measurement |
| CN104318393A (en) * | 2014-10-27 | 2015-01-28 | 北京智博高科生物技术有限公司 | Radiopharmaceutical production management system |
| CN104484793A (en) * | 2014-12-02 | 2015-04-01 | 北京智博高科生物技术有限公司 | Dynamic calibration system for radiopharmaceutical radionuclide activity |
| CN107462915A (en) * | 2017-04-07 | 2017-12-12 | 中国人民解放军北京军区疾病预防控制中心 | A kind of real-time measuring method of radiopharmaceutical activity and system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN111091302A (en) | 2020-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20110082811A1 (en) | Tracking recordation system for packages | |
| CN107408235A (en) | For the system and method for the transport for promoting the parcel to retracting commodity | |
| CN104484793B (en) | A kind of dynamic calibration system of radioactive drugs nucleic activity | |
| CN104318466A (en) | Transaction system and transaction settlement method | |
| CN106528701B (en) | Cross-border merchandise news sending method and system | |
| CN107392691A (en) | Electric business takes the operation system and method for the key of goods one generation hair in real time | |
| CN108090777A (en) | A kind of store commodity issue Auditing System | |
| CN108090754A (en) | A kind of store payment and settlement manages system | |
| CN106952135A (en) | Online transaction method and trading platform system based on staple commodities transaction platform | |
| CN108053165B (en) | Method and system for calculating freight rate through packing list summary data | |
| CN111091302B (en) | Nuclide drug order processing method and nuclide drug customization system | |
| CN109754271A (en) | A kind of product promotion method and system | |
| CN109711823A (en) | A kind of cross-border declaration system and method | |
| CN111429196A (en) | Order processing method and device, storage medium and e-commerce system | |
| CN109461015A (en) | A kind of method and system for sharing and calculate automatically international logistics kinds of goods freight charges unit price | |
| CN106570664A (en) | E-commerce logistics system | |
| CN106952136A (en) | Order generation method and trading platform system based on staple commodities transaction platform | |
| JP5602591B2 (en) | Traceability management system | |
| CN105719174A (en) | Website platform docking system and method | |
| CN111339259B (en) | Method for pre-packaging materials to be delivered in SAP | |
| JP2005235053A (en) | Distribution system for direct sale in specific remote place of agricultural product | |
| CN115018585A (en) | Crop culture method and related equipment thereof | |
| CN107545382A (en) | Distribution plan manufacturing system and distribution plan preparation method | |
| CN107564576A (en) | drug monitoring system and method based on short message | |
| WO2022040261A1 (en) | Methods and systems for product order fulfillment, processing, and management with reusable product and shipping containers |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |