CN111089750A - Sampling device - Google Patents
Sampling device Download PDFInfo
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- CN111089750A CN111089750A CN202010072246.5A CN202010072246A CN111089750A CN 111089750 A CN111089750 A CN 111089750A CN 202010072246 A CN202010072246 A CN 202010072246A CN 111089750 A CN111089750 A CN 111089750A
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- material returning
- drill
- sample
- sampling device
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- 238000005070 sampling Methods 0.000 title claims abstract description 60
- 239000000463 material Substances 0.000 claims abstract description 113
- 229910000831 Steel Inorganic materials 0.000 claims description 18
- 239000010959 steel Substances 0.000 claims description 18
- 239000003638 chemical reducing agent Substances 0.000 claims description 16
- 238000009434 installation Methods 0.000 claims description 14
- 230000005540 biological transmission Effects 0.000 claims description 12
- 238000000429 assembly Methods 0.000 claims description 7
- 230000000712 assembly Effects 0.000 claims description 7
- 239000000523 sample Substances 0.000 abstract description 51
- 230000008014 freezing Effects 0.000 abstract description 11
- 238000007710 freezing Methods 0.000 abstract description 11
- 238000010257 thawing Methods 0.000 abstract description 7
- 239000012520 frozen sample Substances 0.000 abstract description 4
- 230000000007 visual effect Effects 0.000 description 6
- 230000033001 locomotion Effects 0.000 description 5
- 239000012472 biological sample Substances 0.000 description 4
- 238000006073 displacement reaction Methods 0.000 description 4
- 238000005553 drilling Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 3
- 238000001125 extrusion Methods 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000035943 smell Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a sampling device, which comprises a shell, wherein a driving assembly, a drill point assembly and a material returning assembly are arranged in the shell, the drill point assembly comprises a drill point and a drill point mounting shaft, the drill point mounting shaft is connected with the driving assembly and can drive the drill point to rotate under the driving of the driving assembly, the material returning assembly comprises a knob and a material returning screw rod, the material returning screw rod is connected with the drill point assembly, and the knob is connected with the material returning screw rod and can drive the material returning screw rod to rotate for material returning; the laboratory technician one-hand operation to the female sample centre gripping that will take a sample is on special freezing mesa, and the special stop collar of centre gripping is pressed down sampling device and is carried out sample work to start button on the sample test tube. And when the sampling amount meets the original set amount, finishing the sampling work and screwing out the sampled sample to the target container. On the premise of keeping the frozen state of the mother sample without freezing and thawing, the frozen sample is taken out in a targeted and quantitative manner, and the original tissue properties of the experimental sample are kept to the maximum extent.
Description
Technical Field
The invention relates to the field of sampling devices, in particular to a sampling device.
Background
In the current biological sample library, a simpler and original mode is adopted for various sampling means of frozen samples. Under the freezing state of-196 degrees or-80 degrees and the like, the biological sample becomes abnormally hard, if a part of the sample needs to be taken out for an experiment, a researcher usually freezes and freezes the mother sample firstly, then uses a forceps tip or a tool nose to knock the surface of the mother sample, so that cracks are generated on the surface of the mother sample and even small sample blocks are collapsed, and the small sample blocks are picked up and put into a target container for the next scientific experiment.
However, the repeated freezing and thawing can cause great loss of RNA in biological samples, and some brain tissue proteins can lose RNA or degrade after freezing and thawing, which directly influences the medical research results. Some samples are also very precious, and quantitative sampling is used for scientific research experiments on the premise of limited mother samples, so that the problem which needs to be solved urgently in a laboratory is solved. For pathological change biological samples such as tumor, pathological change central tissues need to be taken at fixed points to the maximum extent during research, and the conventional traditional means cannot solve the problems.
Disclosure of Invention
In view of the above-mentioned shortcomings, the present invention provides a sampling device capable of performing targeted drilling of frozen tissue samples while maintaining the original cryofrozen state of the samples.
In order to achieve the above purpose, the embodiment of the invention adopts the following technical scheme:
the utility model provides a sampling device, sampling device includes the casing, be equipped with drive assembly, drill point subassembly and material returned subassembly in the casing, the drill point subassembly includes drill point and drill point installation axle, drill point installation axle is connected with drive assembly and can drives the drill point rotation under drive assembly's drive, the material returned subassembly includes knob and material returned lead screw, the material returned lead screw with the drill point subassembly is connected, the knob is connected with the material returned lead screw and can drives the material returned lead screw rotation and carry out the material returned.
According to one aspect of the invention, the material returning assembly further comprises a limiting screw rod, a main gear, a first pinion and a second pinion, the knob is connected with the axis of the main gear, the first pinion is arranged on the material returning screw rod, the second pinion is arranged on the limiting screw rod, the first pinion and the second pinion are respectively located on an upper plane and a lower plane, and the main gear can move up and down to be respectively meshed with the first pinion and the second pinion.
According to one aspect of the invention, a spring is arranged above the main gear and is in interference fit with the upper end of the shell, and the first auxiliary gear and the main gear are normally located on the same plane.
According to one aspect of the invention, the drill point comprises a hollow drill point needle body and a drill point mandril positioned in the drill point needle body, the material returning screw rod is provided with a material returning nut, and the material returning nut can move up and down to extrude the upper end of the drill point mandril or separate from the upper end of the drill point mandril when the material returning screw rod rotates.
According to one aspect of the invention, the limiting screw rod is provided with a limiting nut, and the limiting nut can move up and down when the limiting screw rod rotates so as to limit the up-and-down moving upper end position of the material returning nut.
According to one aspect of the invention, the shell is provided with scales, the limit nut is connected with a limit indicator capable of moving synchronously with the limit nut, the upper end of the drill point ejector rod is provided with a feeding indicator capable of moving synchronously with the drill point ejector rod, the material returning nut is connected with a material returning indicator capable of moving synchronously with the material returning nut, and the limit indicator, the feeding indicator and the material returning indicator are arranged on the scales.
According to one aspect of the invention, the drill point component further comprises a drill point fixing sleeve, a steel ball and a drill point ejection spring, the drill point fixing sleeve is sleeved on the drill point mounting shaft, the drill point ejection spring is arranged between the drill point fixing sleeve and the drill point mounting shaft, a groove is arranged in the drill point fixing sleeve, and the steel ball is arranged in the groove.
According to one aspect of the invention, the driving assembly comprises a circuit board, a motor, a speed reducer and a transmission gear set, wherein a power interface is arranged on the circuit board, the motor is respectively connected with the circuit board and the speed reducer, the speed reducer is connected with the drill point mounting shaft through the transmission gear set, and the circuit board is connected with a button switch arranged on the shell.
According to one aspect of the invention, the sampling device further comprises an upper needle assembly and a lower needle assembly, the upper needle assembly and the lower needle assembly comprise a bracket and a rotating shaft, the bracket is movably connected with the rotating shaft and can rotate around the rotating shaft, a drill needle fixing sleeve buckle is arranged at the end part of the bracket on one side of the rotating shaft, a pressing seat is arranged at the end part of the bracket on the other side of the rotating shaft, and the drill needle fixing buckle is movably connected with the drill needle fixing sleeve.
According to one aspect of the invention, the upper and lower needle assemblies further comprise a mounting seat, a through hole is formed in the mounting seat, a button is arranged in the through hole, and the button can move in the through hole and is connected with the pressing seat.
The implementation of the invention has the advantages that: the sampling device comprises a shell, wherein a driving assembly, a drill point assembly and a material returning assembly are arranged in the shell, the drill point assembly comprises a drill point and a drill point mounting shaft, the drill point mounting shaft is connected with the driving assembly and can drive the drill point to rotate under the driving of the driving assembly, the material returning assembly comprises a knob and a material returning screw rod, the material returning screw rod is connected with the drill point assembly, and the knob is connected with the material returning screw rod and can drive the material returning screw rod to rotate for material returning; the laboratory technician one-hand operation to the female sample centre gripping that will take a sample is on special freezing mesa, and the special stop collar of centre gripping is pressed down sampling device and is carried out sample work to start button on the sample test tube. And when the sampling amount meets the original set amount, finishing the sampling work and screwing out the sampled sample to the target container. On the premise of keeping the frozen state of the mother sample without freezing and thawing, the frozen sample is taken out in a targeted and quantitative manner, and the original tissue properties of the experimental sample are kept to the maximum extent. The device can avoid artificial freeze thawing damage and sample waste when precious samples are sampled. The researchers do not directly contact the sample, and various unpleasant smells are avoided.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic diagram of the internal structure of a sampling device according to the present invention;
FIG. 2 is a schematic structural view of a material returning assembly according to the present invention;
FIG. 3 is a schematic view of a driving assembly according to the present invention;
FIG. 4 is a schematic cross-sectional view of a drill bit assembly according to the present invention;
FIG. 5 is a schematic external view of a sampling device according to the present invention;
FIG. 6 is a schematic view of a drill point according to the present invention;
fig. 7 and 8 are schematic structural views of the upper and lower needle assemblies according to the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
As shown in fig. 1 to 8, a sampling device includes a housing 1, a driving assembly 2, a drill point assembly 3 and a material returning assembly 4 are arranged in the housing, the drill point assembly includes a drill point 31 and a drill point mounting shaft 32, the drill point mounting shaft is connected with the driving assembly and can drive the drill point to rotate under the driving of the driving assembly, the material returning assembly includes a knob 41 and a material returning screw rod 42, the material returning screw rod is connected with the drill point assembly, and the knob 41 is connected with the material returning screw rod and can drive the material returning screw rod to rotate for material returning.
In this embodiment, the material returned subassembly includes installing support 40, the installing support is fixed in the casing, the installing support top is equipped with apron 401, the knob sets up in the apron top, the apron is equipped with the through-hole, is equipped with knob pole 45 in the through-hole, be equipped with mount table 402 and lower mount table 403 on the installing support of apron below, it is equipped with master gear 43 and first pinion 44 on the mount table to go up, knob pole and knob fixed connection are passed through in the axle center of master gear, material returned lead screw swing joint is between last mount table 402 and lower mount table 403, mount table 402 and first pinion 44 axle center fixed connection are passed to the upper end of material returned lead screw, master gear and first pinion meshing. The material returning screw rod is provided with threads and is sleeved with a material returning nut 46, a sliding rail or smooth contact connection is arranged between the material returning nut and the mounting bracket, so that the material returning nut can move up and down under the action of the threads when the material returning screw rod rotates. The material returned nut is connected with a material returned indictor 461 that can follow material returned nut synchronous motion, be equipped with scale 11 and visual groove 12 on the casing, can see the position of material returned indictor through visual groove, can more clearly judge the removal displacement of material returned indictor through the scale.
In this embodiment, the drill bit 31 includes a hollow drill bit body 311 and a drill bit top rod 312 located in the drill bit body, and the material returning nut can move up and down to press or separate the upper end of the drill bit top rod 312 when the material returning screw rod rotates. The knob 41 is turned to drive the main gear 43 to rotate, and the first pinion 44 is engaged with the main gear 43 to rotate the first pinion, so as to drive the material returning screw rod to rotate, at this time, the material returning nut can move up and down, and then the drilled material is pushed out of the drill point through the drill point ejector rod 312. The upper end of the drill point ejector rod is provided with a feeding indicator 313 capable of moving synchronously with the drill point ejector rod, the position of the feeding indicator can be seen through the visual groove, and the moving displacement of the feeding indicator can be judged more clearly through scales.
In this embodiment, the drill point component 3 further includes a drill point fixing sleeve 33, a steel ball 34 and a drill point ejection spring 35, the drill point fixing sleeve is sleeved on the drill point mounting shaft, the drill point ejection spring is arranged between the drill point fixing sleeve and the drill point mounting shaft, a groove is arranged in the drill point fixing sleeve, and the steel ball is arranged in the groove. The drill point mounting shaft is provided with an ejection spring which acts on the drill point fixing sleeve all the time to eject the drill point fixing sleeve to a position flush with the end face of the drill point mounting shaft.
In this embodiment, when the drill point is installed, the drill point fixing sleeve is pulled by external force, the spring force of the ejection spring is overcome, the fixing steel balls slide into the grooves of the drill point fixing sleeve, the freedom degree of the steel balls is released, the drill point is inserted into the drill point installation shaft at the moment, after the steel balls of the drill point are ejected by the polygonal drill point sleeve, the drill point is continuously inserted into the drill point installation shaft until the installation limit is reached, the external force is released at the moment, the drill point fixing sleeve is ejected to the end face parallel and level position of the installation shaft by the spring again, meanwhile, the steel balls of the drill point slide into the grooves of the polygonal drill point sleeve under the extrusion force, the drill point sleeve is clamped, the vertical movement.
In this embodiment, an automatic upper and lower needle assembly 5 may be used, which includes a bracket 51 and a rotating shaft 52, the bracket is movably connected with the rotating shaft and can rotate around the rotating shaft, the end of the bracket on one side of the rotating shaft is provided with a drill fixing sleeve fastener 53, the end of the bracket on the other side of the rotating shaft is provided with a pressing seat 54, and the drill fixing fastener is movably connected with the drill fixing sleeve.
In practical application, the upper and lower needle assemblies further comprise a mounting seat 56, a through hole is formed in the mounting seat, a button 55 is arranged in the through hole, and the button can move in the through hole and is connected with the pressing seat. And (3) pressing the button by external force to enable the button to downwards prop against a pressing seat of the support, applying force to enable the support to rotate around the rotating shaft, driving the fastener of the drill point fixing sleeve to upwards move, releasing the freedom degree of the steel ball of the drill point, and installing or detaching the drill point.
In this embodiment, the driving assembly 2 includes a circuit board 21, a motor 22, a speed reducer 23 and a transmission gear set 24, the circuit board is provided with a power interface 211, the motor is connected with the circuit board and the speed reducer respectively, the speed reducer is connected with a drill point installation shaft through the transmission gear set, and the circuit board is connected with a button switch 212 arranged on the casing. The motor is connected with a speed reducer, the rotating speed can be adjusted, and the motor drives a transmission gear set to output the rotating force to the drill point mounting shaft. The drill point mounting shaft is internally provided with a polygonal inner hole or an inner hole with a limiting structure, so that the drill point mounting shaft can drive a drill point matched with the drill point when rotating.
The whole sampling device works as follows:
the laboratory technician operates the sampling device by one hand, clamps a mother sample to be sampled on a special freezing table surface, clamps a special limiting sleeve on a sampling test tube, starts a button, presses down the sampling device to perform sampling work, and drives a transmission gear set by a motor and a speed reducer and drives a drill point to rotate to drill the sample; and drilling a sample to the inner wall of the drill point, wherein the stacking height of the drilled sample in the inner wall pushes the drill point ejector rod and the drill point ejector rod pushes the feeding indicator, and after the feeding indicator rises to the set height, the quantitative sampling is finished (the sample amount is converted according to a volume formula and the bonding density). And (4) screwing the knob, ejecting the sample to a target container, and finishing one-time sampling. The special stop collar is equipped with on the mother's sample test tube, can be according to the sample condition, the free choice sampling point. The whole sampling process is completed on a low-temperature workbench, and the temperature of the mother sample and the temperature of the taken sample are ensured in the whole process. And pressing the automatic upper and lower needle button to automatically separate the used drill needle from the sampling device. And installing a new drill point to the sampling device, and starting the next sampling operation.
Example two
As shown in fig. 1 to 8, a sampling device includes a housing 1, a driving assembly 2, a drill point assembly 3 and a material returning assembly 4 are arranged in the housing, the drill point assembly includes a drill point 31 and a drill point mounting shaft 32, the drill point mounting shaft is connected with the driving assembly and can drive the drill point to rotate under the driving of the driving assembly, the material returning assembly includes a knob 41 and a material returning screw rod 42, the material returning screw rod is connected with the drill point assembly, and the knob 41 is connected with the material returning screw rod and can drive the material returning screw rod to rotate for material returning.
In this embodiment, the material returning assembly includes a mounting bracket 40 fixed in the housing, a cover plate 401 is disposed above the mounting bracket, the knob is disposed above the cover plate, the cover plate is provided with a through hole, a knob rod 45 is disposed in the through hole, an upper mounting table 402 and a lower mounting table 403 are disposed on the mounting bracket below the cover plate, a main gear 43, a first pinion 44 and a second pinion 47 are disposed on the upper mounting table, the first pinion and the second pinion are respectively located on two different upper and lower planes, the main gear can move up and down to be respectively engaged with the first pinion and the second pinion, a spring 405 is disposed above the main gear to be abutted to an upper end of the housing in an interference fit manner, and the first pinion and the main gear are normally located on the same plane; the axle center of master gear passes through knob pole and knob fixed connection, material returned lead screw swing joint is between last mount table 402 and mount table 403 down, goes up mount table 402 and still is equipped with spacing lead screw 404 down between the mount table 403, the upper end of material returned lead screw passes mount table 402 and first pinion 44 axle center fixed connection, the upper end of spacing lead screw passes mount table 402 and second pinion 47 axle center fixed connection. The material returning screw rod is provided with threads and is sleeved with a material returning nut 46, a sliding rail or smooth contact connection is arranged between the material returning nut and the mounting bracket, so that the material returning nut can move up and down under the action of the threads when the material returning screw rod rotates. The limiting screw rod is provided with threads and sleeved with a limiting nut 406, and a sliding rail or smooth contact connection is arranged between the limiting nut and the mounting bracket, so that the limiting nut can move up and down under the action of the threads when the limiting screw rod rotates. The limiting nut is positioned above the material returning nut and limits the space where the material returning nut continues to rise. The material returned nut is connected with a material returned indictor 461 that can follow material returned nut simultaneous movement, limit nut is connected with a spacing indictor 407 that can follow limit nut simultaneous movement, be equipped with scale 11 and visual groove on the casing, can see material returned indictor and spacing indictor's position through visual groove, can more clearly judge material returned indictor and spacing indictor's removal displacement through the scale. The knob is screwed to drive the main gear (a spring is arranged below the mounting bracket cover plate and always presses the main gear), the main gear is meshed with the first pinion, the material returning lead screw is immediately driven, and the material returning nut moves up and down to push the drilled material out of the drill point. The knob is pulled upwards to drive the main gear upwards (to overcome the spring force on the main gear). And the limiting screw rod is meshed with the second auxiliary gear, the limiting nut is driven to move up and down, and the drilling limiting height value is adjusted.
In this embodiment, the drill bit 31 includes a hollow drill bit body 311 and a drill bit top rod 312 located in the drill bit body, and the material returning nut can move up and down to press or separate the upper end of the drill bit top rod 312 when the material returning screw rod rotates. The knob 41 is turned to drive the main gear 43 to rotate, and the first pinion 44 is engaged with the main gear 43 to rotate the first pinion, so as to drive the material returning screw rod to rotate, at this time, the material returning nut can move up and down, and then the drilled material is pushed out of the drill point through the drill point ejector rod 312. The upper end of the drill point ejector rod is provided with a feeding indicator 313 capable of moving synchronously with the drill point ejector rod, the position of the feeding indicator can be seen through the visual groove, and the moving displacement of the feeding indicator can be judged more clearly through scales.
In this embodiment, the drill point component 3 further includes a drill point fixing sleeve 33, a steel ball 34 and a drill point ejection spring 35, the drill point fixing sleeve is sleeved on the drill point mounting shaft, the drill point ejection spring is arranged between the drill point fixing sleeve and the drill point mounting shaft, a groove is arranged in the drill point fixing sleeve, and the steel ball is arranged in the groove. The drill point mounting shaft is provided with an ejection spring which acts on the drill point fixing sleeve all the time to eject the drill point fixing sleeve to a position flush with the end face of the drill point mounting shaft.
In this embodiment, when the drill point is installed, the drill point fixing sleeve is pulled by external force, the spring force of the ejection spring is overcome, the fixing steel balls slide into the grooves of the drill point fixing sleeve, the freedom degree of the steel balls is released, the drill point is inserted into the drill point installation shaft at the moment, after the steel balls of the drill point are ejected by the polygonal drill point sleeve, the drill point is continuously inserted into the drill point installation shaft until the installation limit is reached, the external force is released at the moment, the drill point fixing sleeve is ejected to the end face parallel and level position of the installation shaft by the spring again, meanwhile, the steel balls of the drill point slide into the grooves of the polygonal drill point sleeve under the extrusion force, the drill point sleeve is clamped, the vertical movement.
In this embodiment, an automatic upper and lower needle assembly 5 may be used, which includes a bracket 51 and a rotating shaft 52, the bracket is movably connected with the rotating shaft and can rotate around the rotating shaft, the end of the bracket on one side of the rotating shaft is provided with a drill fixing sleeve fastener 53, the end of the bracket on the other side of the rotating shaft is provided with a pressing seat 54, and the drill fixing fastener is movably connected with the drill fixing sleeve.
In practical application, the upper and lower needle assemblies further comprise a mounting seat 56, a through hole is formed in the mounting seat, a button 55 is arranged in the through hole, and the button can move in the through hole and is connected with the pressing seat. And (3) pressing the button by external force to enable the button to downwards prop against a pressing seat of the support, applying force to enable the support to rotate around the rotating shaft, driving the fastener of the drill point fixing sleeve to upwards move, releasing the freedom degree of the steel ball of the drill point, and installing or detaching the drill point.
In this embodiment, the driving assembly 2 includes a circuit board 21, a motor 22, a speed reducer 23 and a transmission gear set 24, the circuit board is provided with a power interface 211, the motor is connected with the circuit board and the speed reducer respectively, the speed reducer is connected with a drill point installation shaft through the transmission gear set, and the circuit board is connected with a button switch 212 arranged on the casing. The motor is connected with a speed reducer, the rotating speed can be adjusted, and the motor drives a transmission gear set to output the rotating force to the drill point mounting shaft. The drill point mounting shaft is internally provided with a polygonal inner hole or an inner hole with a limiting structure, so that the drill point mounting shaft can drive a drill point matched with the drill point when rotating.
The whole sampling device works as follows:
the laboratory technician operates the sampling device by one hand, clamps a mother sample to be sampled on a special freezing table surface, clamps a special limiting sleeve on a sampling test tube, starts a button, presses down the sampling device to perform sampling work, and drives a transmission gear set by a motor and a speed reducer and drives a drill point to rotate to drill the sample; and drilling a sample to the inner wall of the drill point, wherein the stacking height of the drilled sample in the inner wall pushes the drill point ejector rod and the drill point ejector rod pushes the feeding indicator, and after the feeding indicator rises to the set height, the quantitative sampling is finished (the sample amount is converted according to a volume formula and the bonding density). And (4) screwing the knob, ejecting the sample to a target container, and finishing one-time sampling. The special stop collar is equipped with on the mother's sample test tube, can be according to the sample condition, the free choice sampling point. The whole sampling process is completed on a low-temperature workbench, and the temperature of the mother sample and the temperature of the taken sample are ensured in the whole process. And pressing the automatic upper and lower needle button to automatically separate the used drill needle from the sampling device. And installing a new drill point to the sampling device, and starting the next sampling operation.
The implementation of the invention has the advantages that: the sampling device comprises a shell, wherein a driving assembly, a drill point assembly and a material returning assembly are arranged in the shell, the drill point assembly comprises a drill point and a drill point mounting shaft, the drill point mounting shaft is connected with the driving assembly and can drive the drill point to rotate under the driving of the driving assembly, the material returning assembly comprises a knob and a material returning screw rod, the material returning screw rod is connected with the drill point assembly, and the knob is connected with the material returning screw rod and can drive the material returning screw rod to rotate for material returning; the laboratory technician one-hand operation to the female sample centre gripping that will take a sample is on special freezing mesa, and the special stop collar of centre gripping is pressed down sampling device and is carried out sample work to start button on the sample test tube. And when the sampling amount meets the original set amount, finishing the sampling work and screwing out the sampled sample to the target container. On the premise of keeping the frozen state of the mother sample without freezing and thawing, the frozen sample is taken out in a targeted and quantitative manner, and the original tissue properties of the experimental sample are kept to the maximum extent. The device can avoid artificial freeze thawing damage and sample waste when precious samples are sampled. The researchers do not directly contact the sample, and various unpleasant smells are avoided.
The above description is only an embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention disclosed herein are intended to be covered by the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. The utility model provides a sampling device, sampling device includes the casing, its characterized in that, be equipped with drive assembly, drill point subassembly and material returned subassembly in the casing, the drill point subassembly includes drill point and drill point installation axle, drill point installation axle is connected with drive assembly and can drives the drill point rotation under drive assembly's drive, the material returned subassembly includes knob and material returned lead screw, the material returned lead screw with the drill point subassembly is connected, the knob is connected with the material returned lead screw and can drives the rotation of material returned lead screw and carry out the material returned.
2. The sampling device as claimed in claim 1, wherein the material returning assembly further comprises a limit screw, a main gear, a first pinion and a second pinion, the knob is connected with the main gear, the first pinion is disposed on the material returning screw, the second pinion is disposed on the limit screw, the first and second pinions are respectively located on two different upper and lower planes, and the main gear can move up and down to be engaged with the first and second pinions respectively.
3. A sampler device as claimed in claim 2, wherein a spring is provided above the main gear in interference fit with the upper end of the housing, and the first pinion and the main gear are normally located on the same plane.
4. The sampling device according to claim 2, wherein the drill point comprises a hollow drill point body and a drill point mandril positioned in the drill point body, the material returning screw rod is provided with a material returning nut, and the material returning nut can move up and down to extrude the upper end of the drill point mandril or separate from the upper end of the drill point mandril when the material returning screw rod rotates.
5. The sampling device as claimed in claim 4, wherein the limiting screw is provided with a limiting nut, and the limiting nut can move up and down when the limiting screw rotates to limit the up-and-down moving upper end position of the material returning nut.
6. The sampling device as claimed in claim 5, wherein the housing is provided with a scale, the limit nut is connected with a limit indicator capable of moving synchronously with the limit nut, the upper end of the drill bit mandril is provided with a feeding indicator capable of moving synchronously with the drill bit mandril, the material returning nut is connected with a material returning indicator capable of moving synchronously with the material returning nut, and the limit indicator, the feeding indicator and the material returning indicator are all arranged on the scale.
7. The sampling device as claimed in claim 1, wherein the drill point assembly further comprises a drill point fixing sleeve, a steel ball and a drill point ejection spring, the drill point fixing sleeve is sleeved on the drill point mounting shaft, the drill point ejection spring is arranged between the drill point fixing sleeve and the drill point mounting shaft, a groove is arranged in the drill point fixing sleeve, and the steel ball is arranged in the groove.
8. The sampling device according to claim 7, wherein the driving assembly comprises a circuit board, a motor, a speed reducer and a transmission gear set, the circuit board is provided with a power interface, the motor is respectively connected with the circuit board and the speed reducer, the speed reducer is connected with the drill point mounting shaft through the transmission gear set, and the circuit board is connected with a button switch arranged on the housing.
9. The sampling device as claimed in one of claims 1 to 8, further comprising upper and lower needle assemblies, wherein the upper and lower needle assemblies comprise a bracket and a rotating shaft, the bracket is movably connected with the rotating shaft and can rotate around the rotating shaft, the end of the bracket at one side of the rotating shaft is provided with a drill needle fixing sleeve fastener, the end of the bracket at the other side of the rotating shaft is provided with a pressing seat, and the drill needle fixing fastener is movably connected with the drill needle fixing sleeve.
10. The sampling device of claim 9, wherein the upper and lower needle assemblies further comprise a mounting seat, the mounting seat is provided with a through hole, a button is arranged in the through hole, and the button can move in the through hole and is connected with the pressing seat.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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| CN115491293A (en) * | 2022-11-18 | 2022-12-20 | 深圳希吉亚生物技术有限公司 | Quick sampling device is used in biological enzyme detection |
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