CN111034875A - Natural residue-free disease-resistant growth promoter for aquatic livestock and preparation method thereof - Google Patents

Natural residue-free disease-resistant growth promoter for aquatic livestock and preparation method thereof Download PDF

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CN111034875A
CN111034875A CN201911410875.8A CN201911410875A CN111034875A CN 111034875 A CN111034875 A CN 111034875A CN 201911410875 A CN201911410875 A CN 201911410875A CN 111034875 A CN111034875 A CN 111034875A
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parts
growth promoter
resistant growth
aquatic livestock
natural residue
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许俊才
刘金亮
甘雨海
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Nanjing Firstv Animal Husbandry Technology Co ltd
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Nanjing Firstv Animal Husbandry Technology Co ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms

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Abstract

The invention relates to the technical field of disease-resistant growth promoters, and discloses a natural residue-free disease-resistant growth promoter for aquatic livestock, which is prepared from the main raw materials of isatis root, dandelion, hawthorn, rhizoma atractylodis, magnolia officinalis, epimedium and 60-100 parts of traditional Chinese medicine extract, the natural residue-free disease-resistant growth promoter for aquatic livestock is used as a feed additive and a disease-resistant growth promoter by adding the traditional Chinese medicine components such as the isatis root, the hawthorn, the epimedium herb, the traditional Chinese medicine extract and the like, has low cost, and has obvious effect of improving the disease resistance rate and the survival rate of the broiler chickens, the survival rate can reach 92 to 96 percent, through detecting the content of the chicken manure, the contents of nutrient substances such as protein, phosphorus and calcium are all reduced, the dressing percentage is obviously improved, and the natural residue-free disease-resistant growth promoter for aquatic livestock can be inferred to have good digestion and absorption promoting effect and growth promoting effect on the broiler chickens.

Description

Natural residue-free disease-resistant growth promoter for aquatic livestock and preparation method thereof
Technical Field
The invention relates to the technical field of disease-resistant growth promoters, in particular to a natural residue-free disease-resistant growth promoter for aquatic livestock and a preparation method thereof.
Background
With the continuous development of modern livestock and poultry, livestock and poultry products in China grow rapidly, broiler meat is delicious, taste is good, nutrition is rich, contents of nutrients such as protein and mineral substances are high, fat content is low, digestion is easy, and the feed has an important effect on improving dietary structure of people.
The feed additive is a small amount of or trace substances added in the production, processing and using processes of feeds, has an obvious growth promotion effect, is a raw material inevitably used in the modern feed industry, and has obvious effects on enhancing the nutritive value of basic feeds, improving the production performance of animals, ensuring the health of the animals, saving the feed cost, improving the quality of animal products and the like, but the existing feed additive is difficult to integrate disease resistance and growth promotion into a whole, so that the feed cost is greatly increased.
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a natural residue-free disease-resistant growth promoter for aquatic livestock and a preparation method thereof, and solves the problems that the disease-resistant growth promoter is difficult to dissolve in water, the dissolution rate of the medicine is slow, and the dissolution rate and the release rate are low.
(II) technical scheme
In order to achieve the purpose, the invention provides the following technical scheme: a natural residue-free disease-resistant growth promoter for aquatic livestock comprises the following formula raw materials in parts by weight: 140 parts of isatis root, 30-60 parts of dandelion, 250 parts of hawthorn, 8-15 parts of rhizoma atractylodis, 10-15 parts of mangnolia officinalis, 160 parts of epimedium and 60-100 parts of traditional Chinese medicine extract, wherein the medicinal materials comprise 100-140 parts of isatis root, 30-60 parts of dandelion, 150-250 parts of hawthorn, 8-15 parts of rhizoma atractylodis, 10-15 parts of mangnoli.
Preferably, the traditional Chinese medicine extract comprises astragalus polysaccharides compounds, astragalus flavonoids compounds, eucommia flavonoids compounds and eucommia chlorogenic acids compounds, and the mass ratio of the astragalus polysaccharides compounds, the astragalus flavonoids compounds, the eucommia flavonoids compounds and the eucommia chlorogenic acids compounds is 100:40-80:40-55: 20-30.
Preferably, the preparation method of the natural residue-free disease-resistant growth promoter for aquatic livestock comprises the following steps:
(1) adding ethanol solvent, 100-150 parts of astragalus mongholicus, 100-140 parts of isatis root, 30-60 parts of dandelion, 150-250 parts of hawthorn, 8-15 parts of rhizoma atractylodis, 10-15 parts of mangnolia officinalis, 100-160 parts of epimedium and 60-100 parts of traditional Chinese medicine extract into a planetary ball mill, performing ball milling until the materials pass through a 100-mesh 200-mesh screen at the revolution speed of 400-mesh 600rpm and the rotation speed of 200-mesh 300 rpm.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 2-6:1, adding a ball-milling mixed product, placing the ball-milling mixed product into an oil bath pot, heating for reaction, drying the solution in vacuum to completely remove the solvent, adding distilled water for dilution, controlling the total mass fraction of the solution to be 35-60%, and preparing the natural residue-free disease-resistant growth promoter for aquatic livestock.
Preferably, the heating temperature of the oil bath kettle is 90-120 ℃, and the reaction time is 6-12 h.
(III) advantageous technical effects
Compared with the prior art, the invention has the following beneficial technical effects:
the natural residue-free disease-resistant growth promoter for the aquatic livestock is prepared by adding traditional Chinese medicine components such as isatis roots, hawthorn fruits, epimedium herbs and traditional Chinese medicine extracts to serve as a feed additive and the disease-resistant growth promoter, is low in cost, has an obvious effect of improving the disease resistance rate and the survival rate of broiler chickens, can reach the survival rate of 92-96%, reduces the contents of protein, phosphorus and calcium which are nutrient substances through detecting the content of excrement of chickens, obviously improves the slaughter rate, can be inferred, and has good digestion and absorption promoting effects and growth promoting effects on the broiler chickens.
Detailed Description
To achieve the above object, the present invention provides the following embodiments and examples: a natural residue-free disease-resistant growth promoter for aquatic livestock comprises the following formula raw materials in parts by weight: 140 parts of isatis root, 30-60 parts of dandelion, 250 parts of hawthorn, 8-15 parts of rhizoma atractylodis, 10-15 parts of mangnolia officinalis, 160 parts of epimedium and 60-100 parts of traditional Chinese medicine extracts, wherein the traditional Chinese medicine extracts comprise astragalus polysaccharide compounds, astragalus flavonoid compounds, eucommia flavonoid compounds and eucommia chlorogenic acid compounds in a mass ratio of 100:40-80:40-55: 20-30.
The preparation method of the natural residue-free disease-resistant growth promoter for aquatic livestock comprises the following steps:
(1) adding an ethanol solvent, 100-150 parts of astragalus mongholicus, 100-140 parts of isatis root, 30-60 parts of dandelion, 150-250 parts of hawthorn, 8-15 parts of rhizoma atractylodis, 10-15 parts of mangnolia officinalis, 100-160 parts of epimedium and 60-100 parts of a traditional Chinese medicine extract into a planetary ball mill, wherein the traditional Chinese medicine extract comprises astragalus polysaccharide compounds, astragalus mongholicus flavonoid compounds, eucommia ulmoides flavonoid compounds and eucommia ulmoides chlorogenic acid compounds, the mass ratio of the four is 100:40-80:40-55:20-30, the revolving speed of the ball mill is 400-300 rpm, the rotating speed of the ball mill is 200-300rpm, and ball milling is carried out until the materials pass through a 100-mesh 200-mesh screen.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 2-6:1, adding a ball-milling mixed product, placing the ball-milling mixed product in an oil bath pot, heating to 90-120 ℃, and stirring at a constant speed for reacting for 6-12 hours. And completely removing the solvent by vacuum drying the solution, adding distilled water for dilution, controlling the total mass fraction of the solution to be 35-60%, and preparing the natural residue-free disease-resistant growth promoter for the aquatic livestock.
Example 1
(1) Adding ethanol solvent, 100 parts of astragalus, 100 parts of radix isatidis, 30 parts of dandelion, 150 parts of hawthorn, 8 parts of rhizoma atractylodis, 10 parts of magnolia officinalis, 100 parts of epimedium and 60 parts of traditional Chinese medicine extract into a planetary ball mill, performing ball milling at the revolution speed of 400rpm and the rotation speed of 200rpm of the ball mill until the materials pass through a 100-mesh 200-mesh screen.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 2:1, adding a ball-milling mixed product, placing the ball-milling mixed product in an oil bath pot, heating to 90 ℃, and stirring at a constant speed for reacting for 6 hours. And completely removing the solvent by vacuum drying the solution, adding distilled water for dilution, controlling the total mass fraction of the solution to be 35-60%, and preparing the natural residue-free disease-resistant growth promoter 1 for the aquatic livestock.
Example 2
(1) Adding ethanol solvent, 110 parts of astragalus, 110 parts of isatis root, 60 parts of dandelion, 150 parts of hawthorn, 15 parts of rhizoma atractylodis, 10 parts of magnolia officinalis, 160 parts of epimedium and 65 traditional Chinese medicine extracts into a planetary ball mill, and performing ball milling until the materials pass through a 100-mesh 200-mesh screen when the revolution speed of the ball mill is 600rpm and the rotation speed is 300 rpm.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 2:1, adding a ball-milling mixed product, placing the ball-milling mixed product in an oil bath pot, heating to 120 ℃, and stirring at a constant speed for reaction for 12 hours. And completely removing the solvent by vacuum drying the solution, adding distilled water for dilution, controlling the total mass fraction of the solution to be 35-60%, and preparing the natural residue-free disease-resistant growth promoter 2 for the aquatic livestock.
Example 3
(1) Adding an ethanol solvent, 130 parts of astragalus, 140 parts of isatis root, 40 parts of dandelion, 250 parts of hawthorn, 15 parts of rhizoma atractylodis, 10-15 parts of magnolia officinalis, 100 parts of epimedium and 80 parts of a traditional Chinese medicine extract into a planetary ball mill, performing ball milling at the revolution speed of 400-300 rpm and the rotation speed of 200-300rpm of the ball mill until the materials pass through a 200-mesh screen.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 5:1, adding a ball-milling mixed product, placing the ball-milling mixed product in an oil bath pot, heating to 100 ℃, and stirring at a constant speed for reacting for 8 hours. And completely removing the solvent by vacuum drying the solution, adding distilled water for dilution, controlling the total mass fraction of the solution to be 40%, and preparing the natural residue-free disease-resistant growth promoter 3 for the aquatic livestock.
Example 4
(1) Adding an ethanol solvent, 125 parts of astragalus mongholicus, 120 parts of radix isatidis, 45 parts of dandelion, 200 parts of hawthorn, 11 parts of rhizoma atractylodis, 10-15 parts of mangnolia officinalis, 140 parts of epimedium and 80 parts of traditional Chinese medicine extract into a planetary ball mill, performing ball milling at the revolution speed of 500rpm and the rotation speed of 250rpm of the ball mill until the materials pass through a 200-mesh screen.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 4:1, adding a ball-milling mixed product, placing the ball-milling mixed product in an oil bath pot, heating to 100 ℃, and stirring at a constant speed for reacting for 8 hours. And completely removing the solvent by vacuum drying the solution, adding distilled water for dilution, controlling the total mass fraction of the solution to be 50%, and preparing the natural residue-free disease-resistant growth promoter for the aquatic livestock 4.
Example 5
(1) Adding ethanol solvent, 150 parts of radix astragali, 100 parts of radix isatidis, 30-60 parts of dandelion, 210 parts of hawthorn, 12 parts of rhizoma atractylodis, 11 parts of magnolia officinalis, 160 parts of epimedium and 60-100 parts of traditional Chinese medicine extract into a planetary ball mill, performing ball milling at the revolution speed of 540rpm and the rotation speed of 270rpm of the ball mill until the materials pass through a 100-mesh and 200-mesh screen.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 5:1, adding a ball-milling mixed product, placing the ball-milling mixed product in an oil bath pot, heating to 110 ℃, and stirring at a constant speed for reaction for 10 hours. And completely removing the solvent by vacuum drying the solution, adding distilled water for dilution, controlling the total mass fraction of the solution to be 35%, and preparing the natural residue-free disease-resistant growth promoter 5 for the aquatic livestock.
Example 6
(1) Adding ethanol solvent, 150 parts of radix astragali, 140 parts of radix isatidis, 60 parts of dandelion, 250 parts of hawthorn, 15 parts of rhizoma atractylodis, 15 parts of magnolia officinalis, 160 parts of epimedium and 100 parts of traditional Chinese medicine extract into a planetary ball mill, wherein the revolution speed of the ball mill is 400rpm, and the rotation speed is 300rpm, and carrying out ball milling until the materials pass through a 200-mesh screen.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 6:1, adding a ball-milling mixed product, placing the ball-milling mixed product in an oil bath pot, heating to 120 ℃, and stirring at a constant speed for reaction for 12 hours. And completely removing the solvent by vacuum drying the solution, adding distilled water for dilution, controlling the total mass fraction of the solution to be 60%, and preparing the natural residue-free disease-resistant growth promoter 6 for the aquatic livestock.
The healthy laying cocks are randomly divided into a blank control group and an experimental group 1-6, each group comprises 50 cocks, the initial weight is weighed and recorded, the experimental group 1-6 is respectively fed with quantitative common feed and natural residue-free disease-resistant growth promoting agent 1-6 for aquatic poultry, the weight accounts for 5% of the weight of the common feed, the cocks are respectively fed three times in the morning, at noon and evening, the feeding temperature is 30 ℃, the feeding period is 30 days, excrement samples of the broilers in the blank control group and the experimental group are collected after the feeding period is finished, the content of crude protein, calcium and phosphorus is tested by a liquid chromatography-mass spectrometer, the nutrient absorption rate is compared, and the survival rate, the total weight and the average mass, the dressing percentage and the complete evisceration of the control group and the blank are.
Content of protein, calcium and phosphorus in feces
Figure BDA0002349928080000061
Survival rate, average quality, dressing percentage and total smoothbore percentage
Figure BDA0002349928080000062

Claims (4)

1. The natural residue-free disease-resistant growth promoter for aquatic livestock comprises the following formula raw materials and components in parts by weight, and is characterized in that: 140 parts of isatis root, 30-60 parts of dandelion, 250 parts of hawthorn, 8-15 parts of rhizoma atractylodis, 10-15 parts of mangnolia officinalis, 160 parts of epimedium and 60-100 parts of traditional Chinese medicine extract, wherein the medicinal materials comprise 100-140 parts of isatis root, 30-60 parts of dandelion, 150-250 parts of hawthorn, 8-15 parts of rhizoma atractylodis, 10-15 parts of mangnoli.
2. The natural residue-free disease-resistant growth promoter for aquatic livestock according to claim 1, which is characterized in that: the traditional Chinese medicine extract comprises astragalus polysaccharides compounds, astragalus flavonoids compounds, eucommia flavonoids compounds and eucommia chlorogenic acid compounds, and the mass ratio of the astragalus polysaccharides compounds, the astragalus flavonoids compounds, the eucommia flavonoids compounds and the eucommia chlorogenic acid compounds is 100:40-80:40-55: 20-30.
3. The natural residue-free disease-resistant growth promoter for aquatic livestock according to claim 1, which is characterized in that: the preparation method of the natural residue-free disease-resistant growth promoter for aquatic livestock comprises the following steps:
(1) adding ethanol solvent, 100-150 parts of astragalus mongholicus, 100-140 parts of isatis root, 30-60 parts of dandelion, 150-250 parts of hawthorn, 8-15 parts of rhizoma atractylodis, 10-15 parts of mangnolia officinalis, 100-160 parts of epimedium and 60-100 parts of traditional Chinese medicine extract into a planetary ball mill, performing ball milling until the materials pass through a 100-mesh 200-mesh screen at the revolution speed of 400-mesh 600rpm and the rotation speed of 200-mesh 300 rpm.
(2) Adding distilled water and an ethanol solvent into a reaction bottle, wherein the volume ratio of the distilled water to the ethanol solvent is 2-6:1, adding a ball-milling mixed product, placing the ball-milling mixed product into an oil bath pot, heating for reaction, drying the solution in vacuum to completely remove the solvent, adding distilled water for dilution, controlling the total mass fraction of the solution to be 35-60%, and preparing the natural residue-free disease-resistant growth promoter for aquatic livestock.
4. The natural residue-free disease-resistant growth promoter for aquatic livestock according to claim 2, which is characterized in that: the heating temperature of the oil bath kettle is 90-120 ℃, and the reaction time is 6-12 h.
CN201911410875.8A 2019-12-31 2019-12-31 Natural residue-free disease-resistant growth promoter for aquatic livestock and preparation method thereof Pending CN111034875A (en)

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CN104857376A (en) * 2015-05-11 2015-08-26 安阳工学院 Compound traditional Chinese medicine capable of promoting growing of broilers
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Application publication date: 20200421