CN111012723B - Mosquito-proof wet tissue and preparation method thereof - Google Patents
Mosquito-proof wet tissue and preparation method thereof Download PDFInfo
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- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K8/00—Cosmetics or similar toiletry preparations
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Abstract
The invention relates to an anti-mosquito wet tissue and a preparation method thereof. According to the anti-mosquito functional liquid, copaiba oil and anophelifuge ester are used in a matching mode, and are mixed with other anti-allergy (namely plant extracts), moisturizing and anti-corrosion liquid medicines according to a certain concentration ratio to prepare the functional liquid, a good anti-mosquito effect can be achieved, particularly the synergistic effect of the copaiba oil and the anophelifuge ester is achieved, the anti-mosquito effect is greatly improved, and experiments prove that the anti-mosquito wet tissue can effectively prevent mosquito bites and is effective for more than 4 hours through a third party Aedes albopictus functional test. In addition, the anti-mosquito wet tissue also passes through oral toxicology tests and skin irritation tests of a third party, and experiments prove that the formula of the anti-mosquito functional liquid is safe, non-toxic and non-irritant, can be used for infants and adults, and can be used for wiping various parts on the surface of a body.
Description
Technical Field
The invention belongs to the technical field of wet tissue manufacturing, and particularly relates to an anti-mosquito wet tissue and a preparation method thereof.
Background
Many mosquito-proof products on the market can not achieve 100% mosquito prevention actually, or the mosquito-proof time is only dozens of minutes. The traditional mosquito-proof product has toxic or pungent smell more or less, and cannot be used for infants. Especially, some spray products can not be directly sprayed on the face for use.
And to wet wipe products, mosquito-proof wet wipes in the current industry can be roughly divided into two types:
the first type is wet tissue taking deet as main mosquito-proof effect, and the dosage of the wet tissue is between 5 and 15 percent. Has certain mosquito-proof effect and long time effect. However, the deet has certain toxic and side effects, possibly causes symptoms such as erythema, urticaria and the like to a user, and has certain permeability and irritation to the skin. Therefore, for the daily necessities of the wet tissue which is in direct contact with the skin of a human body, if the deet is used, the using amount of the deet is not too much, and if the using amount is small, the mosquito-preventing effect is inevitably poor unless the safety is not considered, only the mosquito-preventing effect is needed.
The second type of anti-mosquito wet tissue mainly adopts natural plant essential oil with anti-mosquito effect, is called as pure natural and has no additive. But is not known to be purely natural. And the mosquito-proof aging of the pure natural plant mosquito-proof essential oil is very short, only dozens of minutes, and at most dozens of minutes. Is not suitable for long-time outdoor camping. For example, chinese patent CN10634461A discloses a multifunctional environment-friendly wet tissue for infants and a preparation method thereof, the wet tissue comprises high-grade moisture-proof facial tissue and wet tissue liquid, wherein the wet tissue liquid is composed of the following raw materials: deionized water, a preservative, chamomile essential oil, perilla extract, polyhexamethylene guanidine, folium artemisiae argyi extract, absolute ethyl alcohol, xylitol, lavender extract, geranium extract, menthol, eucalyptus oil, olive extract, vitamin E, aloe extract and glycerol. In the patent document, although the wet tissue is mentioned to have the mosquito prevention effect, plant essential oil is adopted, the mosquito prevention effect is inevitably shorter, and the mosquito prevention effect is not good.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides an improved mosquito-proof wet tissue.
The invention also provides a preparation method of the mosquito-proof wet tissue.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
the mosquito-proof wet tissue comprises a wet tissue body and mosquito-proof functional liquid, and the raw material formula of the mosquito-proof functional liquid comprises the following components in percentage by weight:
preferably, the raw material formula of the mosquito-proof functional liquid comprises the following components in percentage by weight:
in a further embodiment, the plant extract is a combination of one or more of a chamomile extract, an aloe vera extract, and a peach leaf extract.
Preferably, the plant extract is a combination of a white-flowered chrysanthemum extract, an aloe extract and a peach leaf extract, wherein the white-flowered chrysanthemum extract accounts for 0.1-0.6% of the total weight of the functional liquid, the aloe extract accounts for 0.1-0.6% of the total weight of the functional liquid, and the peach leaf extract accounts for 0.1-1.05% of the total weight of the functional liquid.
In further embodiments, the humectant is a combination of one or more of 1, 3-butanediol, D-panthenol, dipropylene glycol, PEG-7 glyceryl cocoate.
In a further embodiment, the preservative is one or a combination of several of polyaminopropyl biguanide, phenoxyethanol, and ethylhexyl glycerol.
Preferably, the preservative is a combination of polyaminopropyl biguanide, phenoxyethanol and ethylhexylglycerin, and the polyaminopropyl biguanide accounts for 0.1-0.6% of the total weight of the functional liquid, the phenoxyethanol accounts for 0.2-1.5% of the total weight of the functional liquid, and the ethylhexylglycerin accounts for 0.02-0.15% of the total weight of the functional liquid.
In a further embodiment, the raw material formula of the mosquito-proof functional liquid comprises the following components in percentage by weight:
in a further embodiment, the wet tissue body is non-woven fabric or dust-free paper.
The other technical scheme adopted by the invention is as follows: the preparation method of the anti-mosquito wet tissue comprises the steps of uniformly mixing copaiba ester, anophelifuge ester, a plant extract, a humectant, an antiseptic and water according to the formula of the anti-mosquito functional liquid to prepare the anti-mosquito functional liquid, and then spraying the anti-mosquito functional liquid on a wet tissue body to prepare the anti-mosquito wet tissue.
Due to the application of the technical scheme, compared with the prior art, the invention has the following advantages:
the functional liquid for the mosquito-proof wet tissue is prepared by using the copaiba oil and the anophelifuge ester in a matching way, and mixing the functional liquid with other antiallergic (plant extracts) moisturizing and antiseptic liquid medicines according to a certain concentration ratio, so that a good mosquito-repellent effect can be obtained, particularly, the synergistic effect of the copaiba oil and the anophelifuge ester is realized, the mosquito-repellent effect is greatly improved, and experiments prove that the mosquito-proof wet tissue can effectively prevent mosquito bites through a third party Aedes albopictus functional test, the effective time is more than 4 hours, and the outdoor camping time of personnel can be met. In addition, the anti-mosquito wet tissue also passes through oral toxicology tests and skin irritation tests of a third party, and experiments prove that the formula of the functional liquid for the anti-mosquito wet tissue is safe, non-toxic and non-irritant, even can reach the oral level, can be used for infants and adults, and can be used for wiping various parts on the surface of the body.
The mosquito-proof wet tissue is convenient to carry and use, and can be uniformly wiped on the naked parts (legs, ankles, arms, faces and necks) of the body when people go out to play and work in summer, so that the mosquito-proof wet tissue can effectively prevent mosquitoes from biting for more than 4 hours. And the mask is safe, nontoxic and non-irritant, and can be safely used for the face and neck of the infant which is most easily bitten by mosquitoes.
Detailed Description
Copaiba ester CAS No. 8001-61-4 is a pure natural plant essential oil extracted from a leguminous plant of rainforest of brazil, has a natural woody flavor, has various beneficial effects on the human body, and can also be used as a food additive, and has passed FDA agency food certification in the united states. In recent years, the Gouba ester has been researched and found by Kyogi university of Japan to have a certain mosquito repellent effect. The acute diametral toxicological data LD of copaiba ester is 3790mg/kg, (the acute diametral toxicological data LD of salt is 3000 mg/kg) is safer than that of salt.
The 3- (N-N-butyl-N-acetyl) -ethyl aminopropionate is commonly known as anophelifuge, imatinib and IR3535, and CAS No. 52304-36-6, and is a broad-spectrum, high-efficiency, non-toxic, non-irritating and environment-friendly repellent developed and developed by Germany Merck company. The acute diametral toxicological data LD of the anophelifuge is more than 5000mg/kg, and the acute diametral toxicological data LD of the salt is 3000mg/kg, which is safer than that of the salt.
The inventor discovers through research that copaiba ester and anophelifuge with certain concentration are added into the anti-mosquito functional liquid of the wet tissue and mixed with other anti-allergic, moisturizing and anti-corrosive liquid medicines according to a certain concentration ratio to prepare the functional liquid for the wet tissue, the good mosquito repelling effect can be obtained, the effective time can reach more than 4h, and through oral toxicology tests and skin irritation tests of a third party, experiments prove that the formula of the functional liquid for the anti-mosquito wet tissue is safe, non-toxic and non-irritant, and can be used for infants and adults.
The main mosquito prevention method of the mosquito prevention wet tissue has two aspects: on one hand, the special fragrance emitted by the plant essential oil copaiba ester is the taste which is disliked by mosquitoes, and the mosquitoes can be far away from the emission source of the fragrance (namely the skin surface); on the other hand, the anophelifuge in the anti-mosquito functional liquid can form a protective film on the skin, so that the mosquito can not smell the smell emitted by the body, feel that the mosquito is not a blood-sucking object and can not stay on the surface of the skin. The two effects are both effective, and the mosquito-proof effect is greatly improved.
The invention is further described below. The following examples are only for illustrating the technical solutions of the present invention more clearly, and the protection scope of the present invention is not limited thereby.
The CAS numbers corresponding to the raw materials used in the examples of the present invention are shown in table 1:
table 1 shows CAS numbers corresponding to the raw materials used in examples
Name of raw materials | CAS number |
Copaiba balsam | 8001-61-4 |
3- (N-N-butyl-N-acetyl) -aminopropionic acid ethyl ester (anophelifuge) | 52304-36-6 |
Extract of white-flower spring yellow chrysanthemum | 84649-86-5 |
Aloe extract | 85507-69-3 |
Peach leaf extract | 84012-34-0 |
1, 3-butanediol | 107-88-0 |
D-panthenol | 81-13-0 |
Dipropylene glycol | 110-98-5 |
PEG-7 Glycerol cocoate | 68201-46-7 |
Polyaminopropylbiguanides | 133029-32-0 |
Phenoxyethanol | 122-99-6 |
Ethyl hexyl glycerol | 70445-33-9 |
Pure water | 7732-18-5 |
Example 1
The anti-mosquito wet tissue provided by the embodiment comprises a wet tissue body and an anti-mosquito functional liquid sprayed on the wet tissue body, wherein the raw material formula of the anti-mosquito functional liquid is 6% of copaiba ester, 5% of anophelate, 0.2% of feverfew extract, 0.2% of aloe extract, 0.35% of peach leaf extract, 0.75% of 1, 3-butanediol, 0.5% of D-panthenol, 0.5% of dipropylene glycol, 0.5% of PEG-7 glyceryl cocoate, 0.2% of polyaminopropyl biguanide, 0.5% of phenoxyethanol, 0.05% of ethylhexyl glycerol and 85.25% of pure water.
The specific preparation method of the anti-mosquito wet tissue comprises the following steps:
(1) Preparing mosquito-repellent functional liquid
According to the raw material formula of the mosquito-repellent functional liquid, copaiba ester, anophelifuge, chamomile extract, aloe extract, peach leaf extract, 1, 3-butanediol, D-panthenol, dipropylene glycol, PEG-7 glyceryl cocoate, polyaminopropyl biguanide, phenoxyethanol, ethylhexyl glycerol and water are uniformly mixed to prepare the mosquito-repellent functional liquid.
(2) Making mosquito-proof wet tissue
And (2) uniformly spraying the mosquito-repellent functional liquid prepared in the step (1) on non-woven fabrics or dust-free paper according to a certain amount (2.8 times of the weight of the non-woven fabrics or the dust-free paper), and then packaging by adopting an aluminum film to prepare the mosquito-repellent wet tissue.
Evaluation of Performance
The mosquito-repellent wet tissue prepared in example 1 was tested as follows:
1. effective time for mosquito prevention (detection of Chinese disease prevention and control center for preventing and controlling parasitic disease)
1. Test methods and descriptions
The test method comprises the following steps: according to GB/T13917.9-2009 indoor pesticide effect test and evaluation part 9 of pesticide registration sanitary insecticides: repellent (repellent)
The test insects: aedes albopictus, male adult insects which do not take blood 3-5 days after emergence
The test conditions are as follows: the temperature is 26.3 ℃, and the relative humidity is 67.2 percent
2. Test items and test results
Test items: mosquito repellent effect of the mosquito repellent wet tissue of example 1
And (4) evaluating the drug effect according to the effective protection time (h) of the repellent to the testers.
And (3) test results: see table 2.
Table 2 shows the repelling effect of the mosquito-repellent wet tissue of example 1 on repelling aedes albopictus
Subject of the disease | Effective guard time (h) |
1 | 4 |
2 | 5 |
3 | 4 |
4 | 4 |
Average effective guard time (h) | 4.3 |
As can be seen from table 2, the anti-mosquito wet tissue of example 1 can effectively prevent mosquito bites, and the effective time is more than 4 hours.
2. Detection of anti-mosquito Effect (detection of prevention and control of parasitic diseases in the center of prevention and control of Chinese diseases)
1. Test methods and descriptions
The test basis is as follows: according to GB/T13917.9-2009 indoor pesticide effect test and evaluation part 9 of pesticide registration sanitary insecticide: repellent and GB/T30126-2013 detection and evaluation of mosquito prevention performance of textiles
Test insects: aedes albopictus, male imago not sucking blood 4-7 days after eclosion
The test conditions are as follows: the temperature is 26.4 ℃, and the relative humidity is 63.8 percent
And arranging a test group and a control group, wherein the test group is used for immediately testing after the functional liquid in the wet tissue is coated, and the control group is not coated.
2. Test items and test results
Test items: mosquito-repelling effect of the mosquito-repelling wet wipe of example 1
And (3) test results: see table 3.
Table 3 shows the repelling effect of the mosquito-repellent wet tissue of example 1 on repelling aedes albopictus
Control group stop number (only) | Test group stop number (only) | Repellency Rate (%) |
92 | 0 | 100 |
As can be seen from table 3, the wet anti-mosquito tissue of example 1 has a repellent rate of 100% against aedes albopictus.
3. Acute oral toxicity test (SGS test)
1. Detection standard
& lt & ltDisinfection technical Specification & gt 2002 edition
2. Detecting an environment
SPF animal house, room temperature 22 + -1 deg.C, humidity 60 + -5%.
3. Experimental animals and feed
20 SPF-level Kunming mice (10 females and 10 males) with the weight of 18.0-20.0 g, and experimental animals and feeds are purchased from the center of Guangdong provincial medical experimental animals.
4. Sample processing
(1) Sample treatment: the mosquito-proof wet tissue in the embodiment 1 is cut into pieces and is soaked in ultrapure water according to the experimental design dosage;
(2) Dosage: adopting a maximum test, wherein the test dose is designed to be 5000mg/kg body weight;
(3) Preparation: weighing 25.0g of the cut sample, adding ultrapure water to 100mL, stirring, carrying out water bath at 37 ℃ for 2h, stirring uniformly, cooling to room temperature, and taking the soaking filtrate as a test solution.
5. Test procedure
(1) Contamination: using a gavage needle to orally and once gavage the test solution according to the amount of 0.2mL/10g of body weight, fasting for 4 hours before gavage, freely drinking water, and feeding normal diet after gavage for 1 hour;
(2) And (4) observation: observing for 14 days, recording intoxication symptom and death condition, and calculating LD 50 。
6. Results of the experiment
All the tested animals have no obvious toxic symptom and death (death) in the observation periodRate 0%), so mice had acute toxicity of LD by mouth 50 >5000mg/kg body weight.
4. Skin irritation test (Japanese SOUKEN test)
1. Test methods and descriptions
The test basis is as follows: section 3 skin irritation test of skin irritation test according to "method for carrying out skin irritation and sensitivity test and skin Property measurement and method" of Chapter 1
Subject: 10 Japanese men and women aged 20 years and 60 years, respectively, were 20 in total.
Liquid medicine for test: example 1 functional liquid for mosquito repellent wet tissues, physiological saline and vaseline.
The test method comprises the following steps: the three kinds of test solutions were applied to the inner part of the forearm of a subject, and 20. Mu.l of each solution was applied to 3 regions of the inner part of the forearm. The state of the skin was confirmed by the doctor after 60 minutes and 24 hours, respectively, to judge whether there was an abnormality in the applied skin.
2. Test results
The criteria for determination are shown in Table 4
Table 4 is a score reference for skin testing
Criterion for determination | Determination | Scoring |
No reaction | Negative (-) | 0 |
One point of erythema | Weak positive (±) | 0.5 |
Obvious erythema | Positive (+) | 1.0 |
Erythema, edema, pimples | Strong positive (+ +) | 2.0 |
Erythema, edema, papule and small blisters | Strong positive (+ ++) | 3.0 |
Blister (blister) | Strong positives (+ +++) | 4.0 |
Table 5 shows judgment criteria for skin irritation
Skin irritation index value | Classification |
5.0 or less | Security article |
5.0~15.0 | Permissive article |
15.0~30.0 | To be improved |
30.0 or more | Hazardous article |
Each subject was scored by doctor's observation after 60 minutes and 24 hours of application, respectively, on the scoring scale of table 4, and then according to the formula: skin irritation index = (sum of all subject scores/number of subjects) × 100. As a result, all subjects scored 0 for three medications after 60min of application; all subjects scored 0 for three medications 24 hours after application.
Therefore, the skin irritation index of the mosquito-repellent wet wipe of example 1 was also 0, and the result of the test was regarded as a safe product with reference to the determination criteria of table 5.
Example 2
The anti-mosquito wet tissue provided by the embodiment comprises a wet tissue body and anti-mosquito functional liquid sprayed on the wet tissue body, and the raw material formula of the anti-mosquito functional liquid is shown in table 1. The rest was the same as in example 1.
The mosquito-proof function of the mosquito-proof wet tissue is detected, and the result is as follows: the anti-mosquito aging time is about 1 to 2 hours.
Example 3
The anti-mosquito wet tissue provided by the embodiment comprises a wet tissue body and anti-mosquito functional liquid sprayed on the wet tissue body, and the raw material formula of the anti-mosquito functional liquid is shown in table 1. The rest is the same as example 1.
The mosquito-proof wet tissue of the embodiment is subjected to mosquito-proof detection, and the result is as follows: the anti-mosquito effect is about 6 to 8 hours, no anaphylactic reaction exists, and the effect of preventing mosquito for one day by wiping can be achieved.
Comparative example 1
The wet tissue provided by the comparative example comprises a wet tissue body and the functional liquid sprayed on the wet tissue body, and the raw material formula of the functional liquid is shown in table 1. The rest is the same as example 1.
The difference from the embodiment 1 is that: mosquito repellent ester is not added.
The mosquito-proof wet tissue of the embodiment is subjected to mosquito-proof detection, and the result is as follows: the anti-mosquito effect is about 1 to 2 hours. However, the mosquito-proof wet tissue with the formula increases the use frequency of consumers and causes unnecessary troubles. The mosquito-proof effect of one-time wiping for half a day cannot be met.
Comparative example 2
The wet tissue provided by the comparative example comprises a wet tissue body and the functional liquid sprayed on the wet tissue body, and the raw material formula of the functional liquid is shown in table 1. The rest was the same as in example 1.
The difference from the embodiment 1 is that: copaiba ester was not added.
The mosquito-proof wet tissue of the embodiment is subjected to mosquito-proof detection, and the result is as follows: the anti-mosquito aging time is about 1 to 2 hours. However, the mosquito-proof wet tissue with the formula increases the use frequency of consumers and causes unnecessary troubles. The mosquito-proof effect of one-time wiping for half a day cannot be met.
Comparative example 3
The wet tissue provided by the comparative example comprises a wet tissue body and the functional liquid sprayed on the wet tissue body, and the raw material formula of the functional liquid is shown in table 1. The rest was the same as in example 1.
The mosquito-proof wet tissue of the embodiment is subjected to mosquito-proof detection, and the result is as follows: the anti-mosquito effect is only ten minutes.
Comparative example 4
The wet tissue provided by the comparative example comprises a wet tissue body and the functional liquid sprayed on the wet tissue body, and the raw material formula of the functional liquid is shown in table 1. The rest is the same as example 1.
The anti-mosquito effect of the embodiment can reach 4 hours, the content of the copaiba ester needs to reach 10 percent, however, the copaiba ester with the amount is often too strong in fragrance, and is estimated to be a little pungent for the public and is not easy to accept; in addition, the raw materials are imported from Japan, so that the production cost is not high due to high consumption.
Comparative example 5
The wet tissue provided by the comparative example comprises a wet tissue body and the functional liquid sprayed on the wet tissue body, and the raw material formula of the functional liquid is shown in table 1. The rest is the same as example 1.
The anti-mosquito effect of the mosquito repellent composition can reach 4 hours, however, the content of the anophelifuge needs to reach 11%, and the anophelifuge with the amount of the anophelifuge is often unsafe or not, and the consumer is caused with a question that the concentration of the anophelifuge is too high.
Table 2 shows the raw material formulas of the mosquito repellent functional liquids of examples 2 to 3 and comparative examples 1 to 5
Name of raw materials | Example 2 | Example 3 | Comparative example 1 | Comparative example 2 | Comparative example 3 | Comparative example 4 | Comparative example 5 |
Copaiba balsam | 3% | 13% | 6% | 0% | 0.5% | 10 | 0 |
Mosquito repellent ester | 2% | 12% | 0% | 5% | 0.5% | 0 | 11 |
Extract of white-flower spring yellow chrysanthemum | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% |
Aloe extract | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% |
Peach leaf extract | 0.35% | 0.35% | 0.35% | 0.35% | 0.35% | 0.35% | 0.35% |
1, 3-butanediol | 0.75% | 0.75% | 0.75% | 0.75% | 0.75% | 0.75% | 0.75% |
D-panthenol | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% |
Dipropylene glycol | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% |
PEG-7 Glycerol cocoate | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% |
Polyaminopropylbiguanides | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% | 0.2% |
Phenoxyethanol | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% | 0.5% |
Ethyl hexyl glycerol | 0.05% | 0.05% | 0.05% | 0.05% | 0.05% | 0.05% | 0.05% |
Pure water | 91.25% | 71.25% | 90.25% | 91.25% | 95.25% | 86.25% | 85.25 |
The above embodiments are only for illustrating the technical idea and features of the present invention, and the purpose of the present invention is to enable those skilled in the art to understand the content of the present invention and implement the present invention, and not to limit the protection scope of the present invention by this means. All equivalent changes and modifications made according to the spirit of the present invention should be covered within the protection scope of the present invention.
Claims (3)
1. The mosquito-proof wet tissue comprises a wet tissue body and mosquito-proof functional liquid, and is characterized in that the mosquito-proof functional liquid comprises the following components in percentage by weight: 6% copaiba ester, 5% anophelifuge, 0.2% chamomile extract, 0.2% aloe vera extract, 0.35% peach leaf extract, 0.75%1, 3-butylene glycol, 0.5% D-panthenol, 0.5% dipropylene glycol, 0.5% PEG-7 glyceryl cocoate, 0.2% polyaminopropyl biguanide, 0.5% phenoxyethanol, 0.05% ethylhexyl glycerin and 85.25% water.
2. The mosquito-repellent wet wipe according to claim 1, characterized in that: the wet tissue body is made of non-woven fabrics or dust-free paper.
3. A preparation method of the anti-mosquito wet tissue as claimed in claim 1 or 2, wherein the preparation method comprises the steps of uniformly mixing copaiba ester, anophelifuge, a chamomile extract, an aloe extract, a peach leaf extract, 1, 3-butanediol, D-panthenol, dipropylene glycol, PEG-7 glyceryl cocoate, polyaminopropyl biguanide, phenoxyethanol, ethylhexylglycerol and water according to the formula of the anti-mosquito functional liquid to prepare the anti-mosquito wet tissue, and then spraying the anti-mosquito functional liquid on a wet tissue body to prepare the anti-mosquito wet tissue.
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