CN110999984A - Hypoallergenic infant formula milk powder and preparation method thereof - Google Patents

Hypoallergenic infant formula milk powder and preparation method thereof Download PDF

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CN110999984A
CN110999984A CN201911346012.9A CN201911346012A CN110999984A CN 110999984 A CN110999984 A CN 110999984A CN 201911346012 A CN201911346012 A CN 201911346012A CN 110999984 A CN110999984 A CN 110999984A
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powder
infant formula
milk
hypoallergenic infant
parts
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王世杰
封肖颖
朱宏
魏立华
荀一萍
冯丽莉
薛玉玲
张栋
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Shijiazhuang Junlebao Dairy Co Ltd
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Shijiazhuang Junlebao Dairy Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C21/00—Whey; Whey preparations
    • A23C21/06—Mixtures of whey with milk products or milk components
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C21/00—Whey; Whey preparations
    • A23C21/04—Whey; Whey preparations containing non-milk components as source of fats or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C21/00—Whey; Whey preparations
    • A23C21/08—Whey; Whey preparations containing other organic additives, e.g. vegetable or animal products

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
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Abstract

The invention belongs to the technical field of food, and discloses hypoallergenic infant formula milk powder, which comprises the following active ingredients of raw materials, wherein the raw materials for preparing the active ingredients comprise cow milk, lactose, desalted whey powder subjected to partial enzymolysis, soybean oil, concentrated whey protein powder, anhydrous cream, galacto-oligosaccharide, polyfructose, fructo-oligosaccharide, phospholipid, arachidonic acid powder, compound minerals, compound vitamins, fish oil powder, calcium carbonate, potassium hydroxide, choline chloride and nucleotide; the invention also discloses a preparation method of the hypoallergenic infant formula milk powder, which comprises the steps of mixing, preheating, homogenizing, sterilizing, concentrating, spray drying, adding arachidonic acid powder and nucleotide and the like. The hypoallergenic infant formula milk powder disclosed by the invention is added with the partially enzymolyzed desalted whey powder, so that main protein allergens in the milk powder can be effectively destroyed, the anaphylactic reaction is reduced, and the problem that the conventional infant formula milk powder is easy to cause infant allergy is solved. The product of the invention is suitable for infants.

Description

Hypoallergenic infant formula milk powder and preparation method thereof
Technical Field
The invention belongs to the technical field of food, and relates to infant milk powder, in particular to hypoallergenic infant formula milk powder and a preparation method thereof.
Background
However, in recent years, the cow milk allergy phenomenon of the infants is more and more serious, the infant milk powder is greatly influenced to eat by the infants and even the normal growth and development of the infants, and the investigation finds that about 8 percent of the infants in China have cow milk protein allergy, and casein and β -lactoglobulin existing in the cow milk are main allergic sources and can cause infant eczema, gastrointestinal tract reaction and the like.
At present, the hydrolyzed protein formula milk powder is developed by mainly hydrolyzing allergens at foreign countries aiming at milk allergy infants, the price of the hydrolyzed protein formula milk powder is 2-2.5 times of that of common infant milk powder, and related products at home are few.
Disclosure of Invention
The invention aims to provide hypoallergenic infant formula milk powder to solve the problem that the conventional infant formula milk powder is easy to cause infant allergy;
the invention also aims to provide a preparation method of the hypoallergenic infant formula.
In order to achieve the purpose, the invention adopts the technical scheme that:
the hypoallergenic infant formula milk powder comprises the following raw materials of active ingredients in parts by weight: 60-80 parts of cow milk, 10-15 parts of lactose, 5-15 parts of partially-enzymolyzed desalted whey powder, 3-5 parts of soybean oil, 2-4 parts of concentrated whey protein powder, 1-2 parts of anhydrous cream, 1-3 parts of galacto-oligosaccharide, 0.5-1.5 parts of polyfructose, 0.5-1 part of fructo-oligosaccharide, 0.1-1 part of phospholipid, 0.1-0.3 part of arachidonic acid powder, 0.1-0.3 part of compound mineral, 0.1-0.5 part of compound vitamin, 0.1-0.5 part of fish oil powder, 0.2-0.6 part of calcium carbonate, 0.1-0.5 part of potassium hydroxide, 0.1-0.5 part of choline chloride and 0.01-0.06 part of nucleotide.
As a limitation, the enzymatic hydrolysis degree of the desalted whey powder is 7-15%.
As another limitation, the amount of the surfactant, in weight percent,
20-22% of the desalted whey powder has a molecular weight of less than 0.5kDa,
10-12% of the desalted whey powder has a molecular weight of 0.5-1kDa,
10-12% of the desalted whey powder has a molecular weight of 1-2kDa,
8-10% of the desalted whey powder has a molecular weight of 2-5kDa,
8-10% of the desalted whey powder has a molecular weight of 5-10kDa,
8-10% of the desalted whey powder has a molecular weight of 10-20kDa,
the remaining desalted whey powder had a molecular weight of >20 kDa.
As a third limitation, the hypoallergenic infant formula contains whey protein and casein in a weight ratio of 6: 3-5.
The invention also provides a preparation method of the hypoallergenic infant formula milk powder, which comprises the following steps in sequence:
1) mixing and fully dissolving cow milk, lactose, partially-enzymolyzed desalted whey powder, soybean oil, concentrated whey protein powder, anhydrous cream, galacto-oligosaccharide, polyfructose, fructo-oligosaccharide, phospholipid, compound mineral substances, compound vitamins, fish oil powder, calcium carbonate, potassium hydroxide and choline chloride to prepare a material A;
2) preheating, homogenizing and sterilizing the material A to obtain a material B;
3) concentrating the material B to obtain concentrated milk C;
4) spray drying and cooling the concentrated milk C to obtain a material D;
5) and adding arachidonic acid powder and nucleotide into the material D, and uniformly mixing to obtain the hypoallergenic infant formula milk powder.
As a limitation, the milk is prepared by standardizing raw milk, separating impurities and pasteurizing.
As a further limitation, the pasteurization temperature is 60-75 ℃ and the time is 15-18 s.
As a second limitation, in step 2), the temperature of the preheating is 60-65 ℃;
the homogenizing pressure is 15-18 MPa;
the sterilization temperature is 85-95 ℃ and the sterilization time is 20-30 s.
As a third limitation, in step 3), the concentration process is a four-effect falling film evaporation concentration;
the density of the concentrated milk C is 1080-3。
As a fourth limitation, in the step 4), the air inlet temperature is 160-200 ℃ and the air outlet temperature is 75-95 ℃ in the spray drying process.
Due to the adoption of the technical scheme, compared with the prior art, the invention has the technical progress that:
the ratio of whey protein to casein contained in the hypoallergenic infant formula of the present invention is adjusted to 6: 3-5, the proportion of casein is reduced, and the partially enzymolyzed desalted whey powder is added, so that main protein allergens in the milk powder can be effectively destroyed, and particularly, compared with completely hydrolyzed whey protein, the partially enzymolyzed desalted whey powder can lower the total IgE level in serum and is more effective in reducing anaphylactic reaction;
the hypoallergenic infant formula milk powder disclosed by the invention is added with two prebiotics, namely galactooligosaccharide and fructooligosaccharide, so that the increase of the number of intestinal bifidobacteria can be promoted. The increase of the number of the probiotics can promote the maturity of the immune system of the infant and enhance the immune function, thereby protecting the infant from infection and allergy and further improving the anti-allergy effect of the product;
meanwhile, the hypoallergenic infant formula milk powder disclosed by the invention is added with hypoallergenic protein and various nutrients. The infant formula milk powder can reduce the allergic symptoms of infants, ensure the nutrition required by the growth and development of the infants, and promote the healthy development of the easily allergic infants.
The hypoallergenic infant formula milk powder is suitable for infants, and is particularly suitable for infants with allergy.
Drawings
FIG. 1 is a graph showing the scores of allergic symptoms in example 7 of the present invention;
FIG. 2 is a graph showing the concentration levels of total serum IgE in example 7 of the present invention.
Detailed Description
The present invention is further illustrated by the following specific examples, which are to be construed as merely illustrative, and not limitative of the remainder of the disclosure.
Examples 1-6 hypoallergenic infant formula milk powder and method for preparing the same
Examples 1 to 6 are hypoallergenic infant formula milk powders, respectively, and the raw materials for preparing the effective ingredients are the same, except that the amounts of the raw materials in different examples are different, and the specific details are shown in table 1:
table 1 raw material ratio summary table
Figure 185643DEST_PATH_IMAGE001
In the above examples, the multivitamins contained the following components: vitamin A, vitamin D, vitamin E, and vitamin K1Vitamin B2Vitamin B6Vitamin B12Nicotinamide, folic acid, vitamin C, biotin, pantothenic acid;
the compound mineral comprises the following components: sodium, potassium, copper, magnesium, iron, zinc, manganese, calcium, phosphorus, iodine, chlorine and selenium.
The following is a preparation method of the hypoallergenic infant formula in example 1, which comprises the following steps performed in sequence according to the raw material dosage in example 1:
1) weighing raw milk, standardizing, separating impurities, pasteurizing at 60 deg.C for 18s, and cooling to obtain pasteurized milk;
adding lactose, desalted whey powder subjected to partial enzymolysis, soybean oil, concentrated whey protein powder, anhydrous cream, galacto-oligosaccharide, polyfructose, fructo-oligosaccharide, phospholipid, compound mineral substances, compound vitamins, fish oil powder, calcium carbonate, potassium hydroxide and choline chloride into pasteurized milk, stirring and mixing uniformly, and dissolving sufficiently to obtain a material A;
2) preheating the material A to 64 ℃, homogenizing under the pressure of 15MPa, and then heating to 90 ℃ for sterilization for 25s to obtain a material B;
3) evaporating and concentrating the material B by a four-effect falling film to prepare concentrated milk C, wherein the density of the concentrated milk C is 1085kg/m3
4) Pumping the concentrated milk C into a drying tower by a high-pressure pump for spray drying, wherein the air inlet temperature is 180 ℃, and the air exhaust temperature is 80 ℃ to prepare a material D;
5) and adding arachidonic acid powder and nucleotide into the material D, and uniformly mixing to obtain the hypoallergenic infant formula milk powder.
The following methods for preparing hypoallergenic infant formula milk powder in examples 2 to 6 respectively are the same as the preparation method in example 1 in terms of the raw material dosage in examples 2 to 6 respectively, except that the process parameters in the steps are different, and the specific different process parameters are as follows:
TABLE 2 summary of the different process parameters of examples 2 to 6
Figure 846432DEST_PATH_IMAGE002
The indexes of the partially enzymolyzed whey protein powder added into the hypoallergenic infant formula milk powder corresponding to the embodiments 1-6 are shown in table 3:
TABLE 3 degree of hydrolysis and molecular weight distribution of partially hydrolyzed and desalted whey protein powder
Figure 51017DEST_PATH_IMAGE003
The mass ratio of whey protein and casein added to hypoallergenic infant formulas corresponding to examples 1-6 is shown in table 4:
TABLE 4 summary of the mass ratios of whey protein and casein
Figure 280004DEST_PATH_IMAGE004
Example 7 sensitization evaluation of hypoallergenic infant formulas
110 male BALB/c mice of 4 weeks old were selected and randomly divided into 11 groups (n = 11), which were blank group, CT group, 80% whey protein concentrate (WPC 80) group, hypoallergenic infant formula (pHWF 1-6) group prepared in examples 1-6, whey protein deep-hydrolyzed powder (WPH) group, and normal Skim Milk Powder (SMP), respectively. Wherein the WPC80 group is positive control group, the blank group is not treated, the CT group is only perfused with 10 μ g/one Vibrio Cholerae Toxin (CT), the culture period is 6 weeks, and 1 time per week. The sensitizing dose of the first 5 times of the gavage of the experimental group is 20 mg/mouse, 10 mu g/mouse of vibrio Cholerae Toxin (CT) is supplemented to prevent the mice from generating immune tolerance, the sensitizing dose of the last time of the gavage is 50 mg/mouse, each group takes ultrapure water as a solvent, and the gavage volume is 0.3 mL. The mice of each group were weighed before the last gavage and scored for allergic symptoms 1 hour after gavage. Allergic symptoms occur 15-30 min after gavage and peak 40-50 min after the first symptom occurs. Allergy symptom evaluation system: 0= no symptoms; 1= scratch and rub around nose and head; 2= puffiness around eyes and mouth, hair cocked, reduced activity and/or reduced activity with tachypnea; 3= wheezing, shortness of breath and cyanosis around the mouth and tail; 4= no activity after stimulation, tremor and twitch; 5= death.
As can be seen from the results shown in FIG. 1, the score of allergic symptoms was highest in the WPC80 group, lower in the SMP group, and 0 in each of the blank group, CT group, pHWF1-6 group and WPH group, indicating that the sensitization of whey protein concentrate was the strongest, resulting in severe sensitization of the mice in this group, and mild sensitization of the mice in the ordinary skim milk powder group, whereas the hypoallergenic infant formulas prepared in examples 1-6 had no sensitization symptoms in both of the groups 1-6 and the whey protein deep hydrolyzed powder group.
Serum total IgE levels are one of the markers of allergic reactions, and are clearly associated with allergic symptoms in children. Referring to fig. 2, it can be seen that the total IgE level in the serum of WPC80 group was significantly higher than those of blank group, CT group, pHWF1-6 group and WPH group (P < 0.01), but the difference from SMP group was not significant (P > 0.05). The total IgE level in the serum of the SMP group is obviously higher than that of the blank group, the CT group and the pHWF1-6 group (P < 0.05), but the difference between the SMP group and the WPH group is not obvious (P > 0.05). There was no significant difference in total IgE levels in serum between the blank, CT, pHWF1-6 and WPH groups (P > 0.05), but total IgE levels in serum of pHWF1-6 was lower than in WPH group. These results show that: the whey protein is used as an important allergen in milk protein, can obviously improve the content of total IgE in the serum of an allergic mouse, further strongly stimulates the generation of IgE-mediated immediate-type anaphylactic reaction, and can obviously weaken the stimulation of the whey protein on the IgE-mediated immediate-type anaphylactic reaction after being moderately hydrolyzed. Therefore, by eating the hypoallergenic infant formula milk powder disclosed by the invention, the anaphylactic reaction of mice can be effectively reduced.

Claims (10)

1. The hypoallergenic infant formula milk powder is characterized in that the raw materials for preparing the effective components comprise the following components in parts by weight: 60-80 parts of cow milk, 10-15 parts of lactose, 5-15 parts of partially-enzymolyzed desalted whey powder, 3-5 parts of soybean oil, 2-4 parts of concentrated whey protein powder, 1-2 parts of anhydrous cream, 1-3 parts of galacto-oligosaccharide, 0.5-1.5 parts of polyfructose, 0.5-1 part of fructo-oligosaccharide, 0.1-1 part of phospholipid, 0.1-0.3 part of arachidonic acid powder, 0.1-0.3 part of compound mineral, 0.1-0.5 part of compound vitamin, 0.1-0.5 part of fish oil powder, 0.2-0.6 part of calcium carbonate, 0.1-0.5 part of potassium hydroxide, 0.1-0.5 part of choline chloride and 0.01-0.06 part of nucleotide.
2. A soft unripe cheese containing dietary fiber according to claim 1, wherein the desalted whey powder has an enzymatic hydrolysis degree of 7-15%.
3. Hypoallergenic infant formula according to claim 1, characterized in that, in weight percentages,
20-22% of the desalted whey powder has a molecular weight of less than 0.5kDa,
10-12% of the desalted whey powder has a molecular weight of 0.5-1kDa,
10-12% of the desalted whey powder has a molecular weight of 1-2kDa,
8-10% of the desalted whey powder has a molecular weight of 2-5kDa,
8-10% of the desalted whey powder has a molecular weight of 5-10kDa,
8-10% of the desalted whey powder has a molecular weight of 10-20kDa,
the remaining desalted whey powder had a molecular weight of >20 kDa.
4. The hypoallergenic infant formula according to claim 1, characterized in that the weight ratio of whey protein to casein in the hypoallergenic infant formula is 6: 3-5.
5. A method of preparing a hypoallergenic infant formula according to any one of claims 1-4, characterized in that the method of preparation comprises the following steps carried out in succession:
1) mixing and fully dissolving cow milk, lactose, partially-enzymolyzed desalted whey powder, soybean oil, concentrated whey protein powder, anhydrous cream, galacto-oligosaccharide, polyfructose, fructo-oligosaccharide, phospholipid, compound mineral substances, compound vitamins, fish oil powder, calcium carbonate, potassium hydroxide and choline chloride to prepare a material A;
2) preheating, homogenizing and sterilizing the material A to obtain a material B;
3) concentrating the material B to obtain concentrated milk C;
4) spray drying and cooling the concentrated milk C to obtain a material D;
5) and adding arachidonic acid powder and nucleotide into the material D, and uniformly mixing to obtain the hypoallergenic infant formula milk powder.
6. The method of claim 5, wherein the milk is prepared by standardizing raw milk, separating impurities, and pasteurizing.
7. The method of claim 6, wherein the pasteurization temperature is 60-75 ℃ and the time is 15-18 s.
8. The method for preparing hypoallergenic infant formula according to any one of claims 5 to 7, characterized in that,
in the step 2), the preheating temperature is 60-65 ℃;
the homogenizing pressure is 15-18 MPa;
the sterilization temperature is 85-95 ℃ and the sterilization time is 20-30 s.
9. The method for preparing hypoallergenic infant formula according to any one of claims 5 to 7, characterized in that,
in the step 3), the concentration process is four-effect falling film evaporation concentration;
the density of the concentrated milk C is 1080-3。
10. The method for preparing hypoallergenic infant formula according to any one of claims 5 to 7, characterized in that,
in the step 4), the air inlet temperature in the spray drying process is 160-200 ℃, and the air exhaust temperature is 75-95 ℃.
CN201911346012.9A 2019-12-24 2019-12-24 Hypoallergenic infant formula milk powder and preparation method thereof Pending CN110999984A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111493160A (en) * 2020-05-09 2020-08-07 河北东康乳业有限公司 Antiallergic high-oil hydrolyzed whey ingredient powder and production process thereof
CN111869733A (en) * 2020-07-31 2020-11-03 贝因美股份有限公司 Hypoallergenic lactoprotein functional factor composition, application thereof and hypoallergenic child formula milk powder

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101199300A (en) * 2007-12-17 2008-06-18 石家庄三鹿集团股份有限公司 Yishengyuan powdered milk and preparation method thereof
CN104522175A (en) * 2014-12-29 2015-04-22 光明乳业股份有限公司 Preparation and detecting method for muting sensitive infant formula milk powder
CN108651634A (en) * 2018-04-24 2018-10-16 宁波米拉山国际贸易有限公司 A kind of formula milk and preparation method thereof being suitble to 0 to 6 months babies
CN108967557A (en) * 2018-09-29 2018-12-11 贝因美（杭州）食品研究院有限公司 A kind of infant formula and preparation method thereof
CN110558379A (en) * 2019-09-23 2019-12-13 石家庄君乐宝乳业有限公司 hypoallergenic infant formula dairy product and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101199300A (en) * 2007-12-17 2008-06-18 石家庄三鹿集团股份有限公司 Yishengyuan powdered milk and preparation method thereof
CN104522175A (en) * 2014-12-29 2015-04-22 光明乳业股份有限公司 Preparation and detecting method for muting sensitive infant formula milk powder
CN108651634A (en) * 2018-04-24 2018-10-16 宁波米拉山国际贸易有限公司 A kind of formula milk and preparation method thereof being suitble to 0 to 6 months babies
CN108967557A (en) * 2018-09-29 2018-12-11 贝因美（杭州）食品研究院有限公司 A kind of infant formula and preparation method thereof
CN110558379A (en) * 2019-09-23 2019-12-13 石家庄君乐宝乳业有限公司 hypoallergenic infant formula dairy product and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111493160A (en) * 2020-05-09 2020-08-07 河北东康乳业有限公司 Antiallergic high-oil hydrolyzed whey ingredient powder and production process thereof
CN111869733A (en) * 2020-07-31 2020-11-03 贝因美股份有限公司 Hypoallergenic lactoprotein functional factor composition, application thereof and hypoallergenic child formula milk powder

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