CN110946814A - Skin mesoderm repair liquid and preparation method thereof - Google Patents
Skin mesoderm repair liquid and preparation method thereof Download PDFInfo
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- CN110946814A CN110946814A CN202010056372.1A CN202010056372A CN110946814A CN 110946814 A CN110946814 A CN 110946814A CN 202010056372 A CN202010056372 A CN 202010056372A CN 110946814 A CN110946814 A CN 110946814A
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- mesoderm
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/982—Reproductive organs; Embryos, Eggs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Reproductive Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
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- Developmental Biology & Embryology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a skin mesoderm repair liquid which comprises the following components in parts by weight: 5-10 parts of polyethylene glycol; 3-8 parts of ectoin; 52-6 parts of vitamin B; 2-6 parts of vitamin E; 5-10 parts of nicotinamide; 1-5 parts of micromolecule HA; 5-10 parts of a mucosa repairing agent; 10-20 parts of normal saline. The preparation method comprises the following steps of (1) preparing 5-10 parts of polyethylene glycol; 3-8 parts of ectoin; 52-6 parts of vitamin B; 2-6 parts of vitamin E; 5-10 parts of nicotinamide; 1-5 parts of micromolecule HA; 5-10 parts of a mucosa repairing agent; and mixing 10-20 parts of physiological saline together, putting the mixture into a stirrer to be stirred at the rotating speed of 300rpm/min until the physiological saline is completely dissolved, and reducing the rotating speed to 60rpm/min to ensure that the physiological saline is stirred until no bubbles exist, thus obtaining the skin mesoderm repairing liquid. The hydrolyzed animal placenta extract in the skin mesoderm repair liquid has unique regeneration characteristics, and has unique advantages in stem cell delivery, tissue engineering, wound healing and inflammation prevention compared with other decellularized tissues.
Description
Technical Field
The invention relates to a repair liquid, in particular to a skin mesoderm repair liquid and a preparation method thereof.
Background
At present, for repairing the mesoderm of the skin, although micro-needle beautifying, a radio frequency instrument, an external wrinkle removing paste, essential oil and the like are applied, the effect is very little. Therefore, there is a need for developing a skin mesoderm repair solution with good effect and a preparation method thereof.
Disclosure of Invention
The invention aims to solve the defects and provides a skin mesoderm repair liquid and a preparation method thereof.
The above object of the present invention is achieved by the following technical means: the skin mesoderm repair liquid comprises the following components in parts by weight: 5-10 parts of polyethylene glycol; 3-8 parts of ectoin; 52-6 parts of vitamin B; 2-6 parts of vitamin E; 5-10 parts of nicotinamide; 1-5 parts of micromolecule HA; 5-10 parts of a mucosa repairing agent; 10-20 parts of normal saline.
Preferably, the skin mesoderm repair liquid consists of the following components in parts by weight: 6-9 parts of polyethylene glycol; 4-7 parts of ectoin; 53-5 parts of vitamin B; 3-7 parts of vitamin E; 6-9 parts of nicotinamide; 2-4 parts of micromolecule HA; 6-9 parts of a mucosa repairing agent; 12-18 parts of normal saline.
Preferably, the skin mesoderm repair liquid consists of the following components in parts by weight: 8 parts of polyethylene glycol; 5 parts of ectoin; 54 parts of vitamin B; 4 parts of vitamin E; 8 parts of nicotinamide; 3 parts of micromolecule HA; 8 parts of a mucosa repairing agent; and 15 parts of normal saline.
Preferably, the mucosa repair agent is a hydrolyzed animal placenta extract.
Preferably, the hydrolyzed animal placenta extract is a hydrolyzed placenta extract of swine.
The invention discloses a preparation method of a skin mesoderm repair liquid, which is characterized by comprising the following steps: 5-10 parts of polyethylene glycol; 3-8 parts of ectoin; 52-6 parts of vitamin B; 2-6 parts of vitamin E; 5-10 parts of nicotinamide; 1-5 parts of micromolecule HA; 5-10 parts of a mucosa repairing agent; and mixing 10-20 parts of physiological saline together, putting the mixture into a stirrer to be stirred at the rotating speed of 300rpm/min until the physiological saline is completely dissolved, and reducing the rotating speed to 60rpm/min to ensure that the physiological saline is stirred until no bubbles exist, thus obtaining the skin mesoderm repairing liquid.
Compared with the prior art, the invention has the advantages that: the hydrolyzed animal placenta extract in the skin mesoderm repair liquid has unique regeneration characteristics, and has unique advantages in stem cell delivery, tissue engineering, wound healing and inflammation prevention compared with other decellularized tissues.
Detailed Description
The present invention will be described in more detail with reference to examples.
Example 1: the invention relates to a skin mesoderm repair liquid which comprises the following components in parts by weight: 5 parts of polyethylene glycol; 8 parts of ectoin; 52 parts of vitamin B; 6 parts of vitamin E; 5 parts of nicotinamide; 5 parts of small molecular HA; 5 parts of a mucosa repairing agent; 20 parts of normal saline. The mucosa repairing agent is hydrolyzed animal placenta extract. The hydrolyzed animal placenta extract is hydrolyzed placenta extract of pig. The preparation method comprises the following steps of (1) preparing 5-10 parts of polyethylene glycol; 3-8 parts of ectoin; 52-6 parts of vitamin B; 2-6 parts of vitamin E; 5-10 parts of nicotinamide; 1-5 parts of micromolecule HA; 5-10 parts of a mucosa repairing agent; and mixing 10-20 parts of physiological saline together, putting the mixture into a stirrer to be stirred at the rotating speed of 300rpm/min until the physiological saline is completely dissolved, and reducing the rotating speed to 60rpm/min to ensure that the physiological saline is stirred until no bubbles exist, thus obtaining the skin mesoderm repairing liquid.
Example 2: the invention relates to a skin mesoderm repair liquid which comprises the following components in parts by weight: 8 parts of polyethylene glycol; 5 parts of ectoin; 54 parts of vitamin B; 4 parts of vitamin E; 8 parts of nicotinamide; 3 parts of micromolecule HA; 8 parts of a mucosa repairing agent; and 15 parts of normal saline. The mucosa repairing agent is hydrolyzed animal placenta extract. The hydrolyzed animal placenta extract is hydrolyzed placenta extract of pig. The preparation method comprises the following steps of (1) 8 parts of polyethylene glycol; 5 parts of ectoin; 54 parts of vitamin B; 4 parts of vitamin E; 8 parts of nicotinamide; 3 parts of micromolecule HA; 8 parts of a mucosa repairing agent; and mixing 15 parts of normal saline together, putting the mixture into a stirrer to be stirred at the rotating speed of 300rpm/min until the normal saline is completely dissolved, and reducing the rotating speed to 60rpm/min to stir the mixture till no bubbles exist, thereby obtaining the skin mesoderm repairing liquid.
Example 3: the invention relates to a skin mesoderm repair liquid which comprises the following components in parts by weight: 10 parts of polyethylene glycol; 3 parts of ectoin; 56 parts of vitamin B; 2 parts of vitamin E; 10 parts of nicotinamide; 1 part of micromolecule HA; 10 parts of a mucosa repairing agent; 10 parts of normal saline. The mucosa repairing agent is hydrolyzed animal placenta extract. The hydrolyzed animal placenta extract is hydrolyzed placenta extract of pig. The preparation method comprises the following steps of (1) 10 parts of polyethylene glycol; 3 parts of ectoin; 56 parts of vitamin B; 2 parts of vitamin E; 10 parts of nicotinamide; 1 part of micromolecule HA; 10 parts of a mucosa repairing agent; and mixing 10 parts of normal saline together, putting the mixture into a stirrer to be stirred at the rotating speed of 300rpm/min until the normal saline is completely dissolved, and reducing the rotating speed to 60rpm/min to stir the mixture till no bubbles exist, thereby obtaining the skin mesoderm repairing liquid.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes performed by the present invention or directly or indirectly applied to other related technical fields are included in the scope of the present invention.
Claims (6)
1. A skin mesoderm repair liquid is characterized in that: the composition consists of the following components in parts by weight: 5-10 parts of polyethylene glycol; 3-8 parts of ectoin; 52-6 parts of vitamin B; 2-6 parts of vitamin E; 5-10 parts of nicotinamide; 1-5 parts of micromolecule HA; 5-10 parts of a mucosa repairing agent; 10-20 parts of normal saline.
2. The mesoderm repair liquid according to claim 1, wherein: the skin mesoderm repair liquid comprises the following components in parts by weight: 6-9 parts of polyethylene glycol; 4-7 parts of ectoin; 53-5 parts of vitamin B; 3-7 parts of vitamin E; 6-9 parts of nicotinamide; 2-4 parts of micromolecule HA; 6-9 parts of a mucosa repairing agent; 12-18 parts of normal saline.
3. The mesoderm repair liquid according to claim 1, wherein: the skin mesoderm repair liquid comprises the following components in parts by weight: 8 parts of polyethylene glycol; 5 parts of ectoin; 54 parts of vitamin B; 4 parts of vitamin E; 8 parts of nicotinamide; 3 parts of micromolecule HA; 8 parts of a mucosa repairing agent; and 15 parts of normal saline.
4. The mesoderm repair liquid according to claim 1, wherein: the mucosa repairing agent is hydrolyzed animal placenta extract.
5. The mesoderm repair liquid according to claim 1, wherein: the hydrolyzed animal placenta extract is hydrolyzed placenta extract of pig.
6. The method for preparing a skin mesoderm repair liquid according to claim 1, wherein: 5-10 parts of polyethylene glycol; 3-8 parts of ectoin; 52-6 parts of vitamin B; 2-6 parts of vitamin E; 5-10 parts of nicotinamide; 1-5 parts of micromolecule HA; 5-10 parts of a mucosa repairing agent; and mixing 10-20 parts of physiological saline together, putting the mixture into a stirrer to be stirred at the rotating speed of 300rpm/min until the physiological saline is completely dissolved, and reducing the rotating speed to 60rpm/min to ensure that the physiological saline is stirred until no bubbles exist, thus obtaining the skin mesoderm repairing liquid.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010056372.1A CN110946814A (en) | 2020-01-18 | 2020-01-18 | Skin mesoderm repair liquid and preparation method thereof |
| EP20879268.9A EP4048298A4 (en) | 2019-10-24 | 2020-10-26 | Preparation and use of therapeutic hydrogels |
| PCT/US2020/057431 WO2021081540A1 (en) | 2019-10-24 | 2020-10-26 | Preparation and use of therapeutic hydrogels |
| US17/727,804 US20220249550A1 (en) | 2019-10-24 | 2022-04-24 | Preparation and use of tissue matrix derived powder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010056372.1A CN110946814A (en) | 2020-01-18 | 2020-01-18 | Skin mesoderm repair liquid and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110946814A true CN110946814A (en) | 2020-04-03 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010056372.1A Pending CN110946814A (en) | 2019-10-24 | 2020-01-18 | Skin mesoderm repair liquid and preparation method thereof |
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| Country | Link |
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| CN (1) | CN110946814A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113520965A (en) * | 2021-07-21 | 2021-10-22 | 广州德贝芙生物科技有限公司 | Anti-allergy repairing composition |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103547254A (en) * | 2011-05-18 | 2014-01-29 | 株式会社日冷生物科学 | Wrinkle-improving composition containing placenta-derived component |
| CN108042461A (en) * | 2018-01-25 | 2018-05-18 | 丛硕 | A kind of moisturizing maintenance Essence |
| CN108652994A (en) * | 2018-08-03 | 2018-10-16 | 广东丸美生物技术股份有限公司 | A kind of skin matrix and its preparation method and application with moisturizing, improvement wrinkle and anti-oxidation efficacy |
| CN108853001A (en) * | 2018-09-20 | 2018-11-23 | 北京原肽干细胞医学研究院有限公司 | A kind of skin repair liquid and preparation method thereof containing stem cell extract |
| CN109568151A (en) * | 2019-01-14 | 2019-04-05 | 恒天量子（厦门）科技有限公司 | A kind of Essence skin care moisture saver mask and preparation method thereof containing small-molecular peptides |
| CN110123692A (en) * | 2019-05-24 | 2019-08-16 | 广州维真渼生物科技有限公司 | Extreme-moistening smooth film and preparation method thereof |
-
2020
- 2020-01-18 CN CN202010056372.1A patent/CN110946814A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103547254A (en) * | 2011-05-18 | 2014-01-29 | 株式会社日冷生物科学 | Wrinkle-improving composition containing placenta-derived component |
| CN108042461A (en) * | 2018-01-25 | 2018-05-18 | 丛硕 | A kind of moisturizing maintenance Essence |
| CN108652994A (en) * | 2018-08-03 | 2018-10-16 | 广东丸美生物技术股份有限公司 | A kind of skin matrix and its preparation method and application with moisturizing, improvement wrinkle and anti-oxidation efficacy |
| CN108853001A (en) * | 2018-09-20 | 2018-11-23 | 北京原肽干细胞医学研究院有限公司 | A kind of skin repair liquid and preparation method thereof containing stem cell extract |
| CN109568151A (en) * | 2019-01-14 | 2019-04-05 | 恒天量子（厦门）科技有限公司 | A kind of Essence skin care moisture saver mask and preparation method thereof containing small-molecular peptides |
| CN110123692A (en) * | 2019-05-24 | 2019-08-16 | 广州维真渼生物科技有限公司 | Extreme-moistening smooth film and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113520965A (en) * | 2021-07-21 | 2021-10-22 | 广州德贝芙生物科技有限公司 | Anti-allergy repairing composition |
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