CN110917513A - Scar treatment equipment - Google Patents

Scar treatment equipment Download PDF

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Publication number
CN110917513A
CN110917513A CN201911386228.8A CN201911386228A CN110917513A CN 110917513 A CN110917513 A CN 110917513A CN 201911386228 A CN201911386228 A CN 201911386228A CN 110917513 A CN110917513 A CN 110917513A
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scar tissue
scar
medicine
carrying
ultrasonic
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CN201911386228.8A
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Chinese (zh)
Inventor
陈茉弦
敖丽娟
李喆
陈绍春
罗凯旋
冯湘君
许永安
刘垚
王蕾
蒋飞云
周娅
徐璇
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Kunming Medical University
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Kunming Medical University
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Priority to CN201911386228.8A priority Critical patent/CN110917513A/en
Publication of CN110917513A publication Critical patent/CN110917513A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/10Terrestrial scenes
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00ICT specially adapted for the handling or processing of medical references
    • G16H70/60ICT specially adapted for the handling or processing of medical references relating to pathologies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0004Applications of ultrasound therapy
    • A61N2007/0034Skin treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0039Ultrasound therapy using microbubbles

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Primary Health Care (AREA)
  • General Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Surgical Instruments (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Multimedia (AREA)

Abstract

The embodiment of the application discloses scar treatment equipment. The apparatus comprises: the drug-loaded microbubble injection module is used for injecting drug-loaded microbubbles to a patient with scar tissue; and the ultrasonic emission module is used for carrying out ultrasonic irradiation on the scar tissue so that the medicine-carrying micro-bubbles of the scar tissue are released to the scar tissue from the blood vessel to treat the scar tissue. By executing the technical scheme provided by the embodiment, the safe, convenient and high-targeting treatment effect of inhibiting the scar hyperplasia can be realized. The device has the advantages of convenient operation, no pain, good curative effect, high safety, low requirement on operators and easy implementation. The therapeutic system can improve the utilization rate of the medicine and reduce side effects.

Description

Scar treatment equipment
Technical Field
The embodiment of the application relates to the technical field of medical equipment, in particular to scar treatment equipment.
Background
With the rapid development of the technology level, for the scars which are troubled by people, the effective treatment by adopting the equipment becomes a problem which is concerned by people.
Hypertrophic Scars (HS) are one of the pathophysiological bases of pathological scars, including the interaction between various microcellular effectors, including connective tissues (such as fibroblasts, myofibroblasts, keratinocytes, and the like), abnormal activation, proliferation, synthesis, differentiation, and secretion of growth factors and cytokines, which in turn lead to abnormal collagen synthesis and dysregulation of certain cell signaling pathways for HS formation, such as the TGF- β 1/Smad pathway.
Disclosure of Invention
The embodiment of the application provides a scar treatment device, which can realize safe, convenient and high-targeting treatment effect of inhibiting scar hyperplasia.
The embodiment of the application provides a scar treatment equipment, this equipment includes:
the drug-loaded microbubble injection module is used for injecting drug-loaded microbubbles to a patient with scar tissue;
and the ultrasonic emission module is used for carrying out ultrasonic irradiation on the scar tissue so that the medicine-carrying micro-bubbles of the scar tissue are released to the scar tissue from the blood vessel to treat the scar tissue.
Optionally, the ultrasound transmission module includes:
the fixing unit is used for controlling the pulse signal transmitting unit to be fixed to the scar tissue treatment position;
the pulse signal transmitting unit is used for providing an electric energy pulse signal to the energy converter unit;
and the transducer unit is used for converting the electric energy into sound energy so as to obtain ultrasonic waves with preset frequency.
Optionally, the ultrasound transmitting module is specifically configured to:
the scar tissue is irradiated by ultrasonic, the medicine-carrying micro-bubble is broken through the ultrasonic cavitation effect, so that the tight connection of the vascular endothelial cells is opened, and the medicine components in the medicine-carrying micro-bubble are absorbed and act on the scar tissue after being released.
Optionally, the apparatus further comprises:
the image acquisition module is used for acquiring a scar tissue image of a patient;
and the pathology identification module is used for identifying the pathology of the scar tissue according to the scar tissue image and determining the medicine components in the medicine-carrying microvesicle.
Optionally, the drug components in the drug-loaded microvesicle include: at least one of 5-fluorouracil, verapamil, bleomycin, imiquimod and interferon.
Optionally, the pathology of scar tissue comprises: at least one of scar color, scar shape, and scar depth.
According to the technical scheme provided by the embodiment of the application, the infrared image of the vehicle is acquired through the infrared camera arranged in the car; judging whether the infrared image contains children left in the car or not; if so, generating warning information, and sending the warning information to a terminal which is pre-bound with the vehicle to warn the owner that children are missing from the vehicle. Through adopting the technical scheme that this application provided, can realize omitting the effect of carrying out effectual supervision and warning in the car to children, can the auxiliary user guarantee drive the protection of accomplishing back to children, avoid appearing children and be omitted the condition that there is danger in the car.
Drawings
Fig. 1 is a schematic structural diagram of a scar treatment device according to an embodiment of the present application;
fig. 2 is a schematic view of the treatment effect of the scar treatment device provided in the second embodiment of the present application.
Detailed Description
The present application will be described in further detail with reference to the following drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the application and are not limiting of the application. It should be further noted that, for the convenience of description, only some of the structures related to the present application are shown in the drawings, not all of the structures.
Before discussing exemplary embodiments in more detail, it should be noted that some exemplary embodiments are described as processes or methods depicted as flowcharts. Although a flowchart may describe the steps as a sequential process, many of the steps can be performed in parallel, concurrently or simultaneously. In addition, the order of the steps may be rearranged. The process may be terminated when its operations are completed, but may have additional steps not included in the figure. The processes may correspond to methods, functions, procedures, subroutines, and the like.
Example one
Fig. 1 is a schematic structural diagram of a scar treatment device according to an embodiment of the present application, where the present embodiment may be suitable for treating a scar, and the device may be implemented by software and/or hardware.
As shown in fig. 1, the scar treatment device includes:
a drug-loaded microbubble injection module 110 for injecting drug-loaded microbubbles to a patient with scar tissue;
and the ultrasonic emission module 120 is used for performing ultrasonic irradiation on the scar tissue so that the medicament-carrying microvesicles of the scar tissue are released to the scar tissue from the blood vessel to treat the scar tissue.
Wherein, medicine carrying microbubble injection module can be according to scar tissue's patient's the condition, confirms the injection position to scar tissue's patient, if scar tissue is at patient's four limbs, can adopt and be close the scar tissue position mode of injecting, if at the face, neck and other be not convenient for position of injecting nearby, then can inject through the four limbs at patient, wait for after a period of time, confirm that the medicine carrying microbubble can be transported to scar tissue's position through blood circulation can.
In this embodiment, the ultrasonic transmission module may include a fixing unit, a pulse signal transmission unit, and a transducer unit. The ultrasonic transmitting module can achieve the purpose of irradiating ultrasonic waves by switching on a power supply through the combination of the units. In the technical scheme, the frequency of the ultrasonic wave can be preset, and can also be adjusted according to the condition of scar tissues of a patient. Such as knobs or graphical interfaces for the staff to adjust the ultrasound.
According to the technical scheme provided by the embodiment of the application, the infrared image of the vehicle is acquired through the infrared camera arranged in the car; judging whether the infrared image contains children left in the car or not; if so, generating warning information, and sending the warning information to a terminal which is pre-bound with the vehicle to warn the owner that children are missing from the vehicle. Through adopting the technical scheme that this application provided, can realize omitting the effect of carrying out effectual supervision and warning in the car to children, can the auxiliary user guarantee drive the protection of accomplishing back to children, avoid appearing children and be omitted the condition that there is danger in the car.
On the basis of the above technical solution, optionally, the ultrasound transmitting module is specifically configured to: the scar tissue is irradiated by ultrasonic, the medicine-carrying micro-bubble is broken through the ultrasonic cavitation effect, so that the tight connection of the vascular endothelial cells is opened, and the medicine components in the medicine-carrying micro-bubble are absorbed and act on the scar tissue after being released.
When the medicine-carrying microvesicle circulates to the scar tissue, the scar tissue is irradiated by therapeutic ultrasonic, the microvesicle is broken and the tight connection of vascular endothelial cells is opened through the cavitation effect of the ultrasonic, the medicine is locally and accurately absorbed after being released and acts on the scar tissue to play the role of inhibiting and treating the scar, and the rest tissues are not influenced by the medicine. This technical scheme can improve the target nature of treating scar tissue through such setting, improves treatment to can be through the processing of medicine carrying microbubble, as long as the position of ultrasonic irradiation can act on scar tissue, thereby reduce because the discomfort that the medicine injection led to the fact the patient.
On the basis of the above technical solution, optionally, the apparatus further includes: the image acquisition module is used for acquiring a scar tissue image of a patient; and the pathology identification module is used for identifying the pathology of the scar tissue according to the scar tissue image and determining the medicine components in the medicine-carrying microvesicle. In this technical scheme, can obtain the image of scar tissue through image acquisition module, wherein image acquisition module can include the camera, especially can include the combination of wide angle camera and macro camera. Wherein wide angle camera can be used for supplying the staff to confirm scar tissue's position, and the macro camera can be used for providing clear closely scar tissue image. The pathological recognition module can learn a large number of scars with known pathological conditions by means of machine learning and the like so as to obtain a recognition model capable of recognizing the pathological conditions of scar tissues. Through the arrangement, the position and the pathological condition of scar tissue can be quickly and accurately determined, and the specific scar tissue treatment is facilitated.
On the basis of the above technical scheme, optionally, the drug-loaded microvesicles comprise the following drug components: at least one of 5-fluorouracil, verapamil, bleomycin, imiquimod and interferon. Wherein, the medicine can be one medicine component or the combination of a plurality of components. In addition, other pharmaceutical ingredients may be included. The medicinal components in the medicament-carrying microvesicles can be determined according to the specific condition of scar tissue of a patient needing treatment. The device provided by the technical scheme can be suitable for more types of scar tissues by the arrangement, and the application range of the device is expanded.
On the basis of the above technical solution, optionally, the pathology of the scar tissue includes: at least one of scar color, scar shape, and scar depth. Wherein the scar color may be a direct-looking color, e.g., some scars may be reddish brown, or blackish brown. The scar behavior can be linear, blocky, and other shapes. The depth of the scar may be determined based on the cause of the scar, the elevation of the scar tissue, and the like. The benefit that this technical scheme set up like this can be to the scar of different grade type, confirms different medicine or ultrasonic frequency to can reach the effect that can all carry out effectual treatment to the scar tissue homoenergetic of different grade type.
Example two
Fig. 2 is a schematic view of the treatment effect of the scar treatment device provided in the second embodiment of the present application. The embodiment is further optimized on the basis of the above embodiment, and specifically optimized as follows: the ultrasound transmission module includes: the fixing unit is used for controlling the pulse signal transmitting unit to be fixed to the scar tissue treatment position; the pulse signal transmitting unit is used for providing an electric energy pulse signal to the energy converter unit; and the transducer unit is used for converting the electric energy into sound energy so as to obtain ultrasonic waves with preset frequency.
As shown in fig. 2, the ultrasound transmission module 120 includes: a fixing unit 121 for controlling the pulse signal emitting unit 122 to be fixed to the scar tissue treatment position; a pulse signal transmitting unit 122 for supplying an electric energy pulse signal to the transducer unit 123; and the transducer unit 123 is used for converting the electric energy into the sound energy so as to obtain the ultrasonic wave with the preset frequency.
In this embodiment, optionally, the transducer unit includes: at least one of a linear array transducer, a circular array transducer, a cambered array transducer, and a planar array transducer. The advantage of this arrangement is that it is possible to use either of the transducers to generate ultrasound with high efficiency and at low cost.
The technical scheme provides a safe, convenient and highly targeted treatment system for inhibiting the scar hyperplasia. Before treatment, the scar tissue condition of a patient is comprehensively evaluated, a proper treatment scheme is formulated, then medicine-carrying microvesicles (medicines which can inhibit scar hyperplasia, such as 5-fluorouracil, verapamil, bleomycin, imiquimod or interferon) are injected intravenously, and ultrasound is applied to irradiate the target scar tissue. Patients were followed after treatment. The relevant record of the whole treatment process is recorded into the system so as to optimize and integrally manage the subsequent treatment scheme. The comprehensive evaluation refers to the evaluation of the conditions of the color depth, the size and the like of scar tissues; the therapeutic ultrasonic part comprises a pulse signal transmitting unit, a transducer unit and a fixing unit. The part generates proper treatment ultrasonic waves to accurately act on the positioned scar tissues, a sound field with proper intensity is generated through ultrasonic irradiation, and the medicine-carrying micro-bubbles are continuously compressed and expanded under the action of sound energy until bursting (cavitation effect) releases medicines into the scar tissues while loosening the tight connection and opening of vascular endothelial cells to generate an inhibiting effect.
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present application and the technical principles employed. It will be understood by those skilled in the art that the present application is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the application. Therefore, although the present application has been described in more detail with reference to the above embodiments, the present application is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present application, and the scope of the present application is determined by the scope of the appended claims.

Claims (7)

1. A scar treatment device, comprising:
the drug-loaded microbubble injection module is used for injecting drug-loaded microbubbles to a patient with scar tissue;
and the ultrasonic emission module is used for carrying out ultrasonic irradiation on the scar tissue so that the medicine-carrying micro-bubbles of the scar tissue are released to the scar tissue from the blood vessel to treat the scar tissue.
2. The apparatus of claim 1, wherein the ultrasound transmission module comprises:
the fixing unit is used for controlling the pulse signal transmitting unit to be fixed to the scar tissue treatment position;
the pulse signal transmitting unit is used for providing an electric energy pulse signal to the energy converter unit;
and the transducer unit is used for converting the electric energy into sound energy so as to obtain ultrasonic waves with preset frequency.
3. The device according to claim 1, characterized in that said ultrasound transmission module is particularly adapted to:
the scar tissue is irradiated by ultrasonic, the medicine-carrying micro-bubble is broken through the ultrasonic cavitation effect, so that the tight connection of the vascular endothelial cells is opened, and the medicine components in the medicine-carrying micro-bubble are absorbed and act on the scar tissue after being released.
4. The apparatus of claim 1, further comprising:
the image acquisition module is used for acquiring a scar tissue image of a patient;
and the pathology identification module is used for identifying the pathology of the scar tissue according to the scar tissue image and determining the medicine components in the medicine-carrying microvesicle.
5. The apparatus of claim 4, wherein the drug content of the drug-loaded microvesicles comprises: at least one of 5-fluorouracil, verapamil, bleomycin, imiquimod and interferon.
6. The apparatus of claim 4, wherein the pathology of scar tissue comprises: at least one of scar color, scar shape, and scar depth.
7. The apparatus of claim 2, wherein the transducer unit comprises: at least one of a linear array transducer, a circular array transducer, a cambered array transducer, and a planar array transducer.
CN201911386228.8A 2019-12-30 2019-12-30 Scar treatment equipment Pending CN110917513A (en)

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CN201911386228.8A CN110917513A (en) 2019-12-30 2019-12-30 Scar treatment equipment

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