CN110917496A - Difference frequency electric interference equipment, system and method - Google Patents
Difference frequency electric interference equipment, system and method Download PDFInfo
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- CN110917496A CN110917496A CN201911267110.3A CN201911267110A CN110917496A CN 110917496 A CN110917496 A CN 110917496A CN 201911267110 A CN201911267110 A CN 201911267110A CN 110917496 A CN110917496 A CN 110917496A
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- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/323—Interference currents, i.e. treatment by several currents summed in the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
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- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0531—Measuring skin impedance
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- A—HUMAN NECESSITIES
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- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
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- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/42—Bus transfer protocol, e.g. handshake; Synchronisation
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Abstract
The invention discloses a difference frequency electric interference device, which comprises a user interaction module, a signal generation module, an impedance detection module and a signal output module which are connected in sequence; the user interaction module is used for transmitting the setting parameters of the electric interference signals to the signal generation module according to the requirements input by a receiving user; the signal generating module is used for generating a plurality of paths of current signals with different frequencies according to the received parameters and sending the current signals to the signal output module; the impedance detection module is used for collecting current signals of each pair of electrodes and calculating to obtain a real-time impedance value; and the signal output module is used for transmitting the multipath current signals to the corresponding pairs of electrodes through a plurality of output interfaces so as to enable the intersection region of the multipath current signals on the stimulated object to generate difference frequency signals. The invention has the function of impedance detection, can test the skin impedance in real time, and monitors whether the program electrode is in states of loosening, falling and the like in real time.
Description
Technical Field
The invention relates to the technical field of detection, in particular to a difference frequency electric interference device, a system and a method.
Background
Parkinson's Disease (PD) is one of the major economic burdens of society today and is exacerbated as the progress of "aging" of society advances. Parkinson's disease is currently prevalent in more than 1% of the elderly population, and is the second most common neurodegenerative disorder after alzheimer's disease. The main symptoms of the Parkinson disease comprise motor symptoms of bradykinesia, tremor, rigidity and unstable posture, mental neurological symptoms such as cognitive disorder, sleep disorder and depression, and the like, and the major symptoms have great influence on the life of patients.
Although the pathogenic mechanism of the Parkinson's disease is not yet clarified, scientific research discovers that: the main pathological change in parkinson's disease is degenerative death of Dopaminergic (DA) neurons in the substantia nigra, thereby causing a significant reduction in striatal dopamine levels, which in turn leads to abnormal activity in the striatal-thalamic-cortical pathway. Dopamine neurotransmitter is a chemical messenger involved in the coordinated movement of neurons and muscles, and when the concentration of the neurotransmitter is reduced, symptoms such as tremor, muscle stiffness and bradykinesia occur. Dopamine replacement therapy can improve motor symptoms during the early stages of PD. Levodopa is a precursor drug of dopamine, enters the brain to be decarboxylated to become dopamine to play a pharmacological role, the balance of dopamine and acetylcholine is artificially realized, and the levodopa can be used for treating PD.
The effectiveness of this pharmacological procedure is significant, but as the condition progresses, the response to treatment diminishes, while levodopa results in serious motor complications, including levodopa-induced dyskinesia. This deficiency ultimately leads to difficulty in curing parkinson's disease with conventional dopamine replacement.
Deep Brain Stimulation (DBS) of subthalamic nucleus (STN) was the first treatment for PD in 1994. This approach proves to be very effective in eliminating the motor symptoms of excess and deficiency in the condition. Deep brain stimulation is also currently the most common and effective form of electrical stimulation for the treatment of PD, and is also considered to be the ultimate treatment option in the failure of conventional therapy. However, the application population of DBS is limited, requiring invasive surgical implantation of electrodes on patients, with the risk of serious complications and neuropsychiatric side effects and at higher cost.
Disclosure of Invention
The present invention is directed to a differential frequency electrical interference apparatus and method to solve the above problems.
In order to achieve the purpose, the invention provides the following scheme: a difference frequency electric interference device comprises a user interaction module, a signal generation module, an impedance detection module and a signal output module which are connected in sequence;
the user interaction module is used for transmitting the setting parameters of the electric interference signals to the signal generation module according to the requirements input by the receiving user;
the signal generating module is used for generating a plurality of paths of current signals with different frequencies according to the received parameters and sending the current signals to the signal output module;
the impedance detection module is used for collecting current signals of each pair of electrodes and calculating to obtain a real-time impedance value;
the signal output module is used for transmitting the multipath current signals to a plurality of corresponding pairs of electrodes through a plurality of output interfaces so as to enable the intersection region of the multipath current signals on the stimulated object to generate difference frequency signals.
Preferably, the signal generating module comprises a waveform generator, a hollander current pump; the waveform generator generates sine wave digital signals through built-in data through calculation and transmits the sine wave digital signals to the digital-to-analog converter; the Holland current pump forms a sinusoidal current with a specific current size by reading an analog signal converted by the digital-to-analog converter.
Preferably, the user interaction module comprises a screen; the screen is used for receiving the electric interference parameters input by a user and displaying the electric interference information and the impedance value in real time.
Preferably, the impedance detection module comprises an impedance detection system; the impedance detection system inputs the voltage generated by the current input to the skin into the analog-to-digital converter through the processing of the following circuit and the voltage division circuit; the digital signal is transmitted to a central processing unit by an analog-to-digital converter to calculate an impedance value; and feeding back the real-time calculated impedance value to the user interaction interface.
Preferably, the signal output module comprises a pair of electrodes connected to each of the output interfaces; at least two pairs of the electrodes are arranged at the stimulated part of the stimulated object; each pair of electrodes has a group of impedance detection functions, and the skin impedance can be checked in real time.
Preferably, the difference frequency electrical interference device further comprises a housing; the user interaction module, the impedance detection module and the signal generation module are all arranged in the shell, and the signal output module is arranged outside the shell.
Preferably, the system further comprises an upper computer; and the upper computer is in communication connection with the difference frequency electric interference equipment.
Preferably, a difference frequency electrical interference method is applied to upper computer software of the difference frequency electrical interference system, and includes the following steps: acquiring stimulation parameters sent by the difference frequency electrical interference equipment, and determining electrode combinations corresponding to the stimulation parameters; acquiring the impedance of a stimulated object sent by the difference frequency electrical interference equipment, and judging whether the electrode combination is qualified in connection or not according to the impedance of the stimulated object; when the electrode combination is qualified in connection, acquiring electric field information sent by the difference frequency electric interference equipment; and inputting the electric field information into an electric field model corresponding to the electrode combination to obtain and display an electric field dynamic image in real time.
Preferably, the method further comprises: in the process of electric interference, acquiring and displaying the impedance of the stimulated object in real time, and monitoring whether the electrode combination is qualified in connection or not according to the impedance of the stimulated object; when the electrode combination is qualified in connection, receiving electrical interference information sent by the difference frequency electrical interference equipment; recording experimental data of the stimulated object according to the electrical interference information, and displaying the electrical interference information in real time; and when the electrode combination connection is unqualified, sending out an alarm prompt.
The invention discloses the following technical effects: the invention provides a difference frequency electric interference device, which transmits two or more groups of currents with different frequencies to a stimulated object through two or more pairs of electrodes, and in the crossing region of the currents, pulse currents with low frequency modulation, namely difference frequency signals, can be generated, and the low frequency modulation currents have the regulating effect on brain cells. Because the low-frequency modulation current can stimulate the deep part of the brain without influencing the surface neuron cells, the defect that the low-frequency current cannot penetrate into the brain tissue can be overcome, the safety is high, a user is more willing to accept the low-frequency modulation current, and the applicability is strong. Meanwhile, the device also has an impedance detection function, can test skin impedance in real time, monitors whether the program electrode is in states of loosening, falling and the like in real time, and can effectively feed back the state of an experiment in real time.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without inventive exercise.
FIG. 1 is a schematic flow diagram of the present invention;
FIG. 2 is a schematic circuit diagram of a portion of a user interaction module according to the present invention;
FIG. 3 is a schematic circuit diagram of a signal generating module according to the present invention;
FIG. 4 is a signal attenuation circuit of the present invention;
fig. 5 shows an operational amplifier front-end circuit, a voltage follower, according to the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.
Referring to fig. 1 to 5, the present embodiment provides a difference frequency electrical interference device, which includes a user interaction module, a signal generation module, an impedance detection module, and a signal output module, which are connected in sequence;
the user interaction module is used for transmitting the setting parameters of the electric interference signals to the signal generation module according to the requirements input by the receiving user;
the signal generating module is used for generating a plurality of paths of current signals with different frequencies according to the received parameters and sending the current signals to the signal output module;
the impedance detection module is used for collecting current signals of each pair of electrodes and calculating to obtain a real-time impedance value;
the signal output module is used for transmitting the multipath current signals to a plurality of corresponding pairs of electrodes through a plurality of output interfaces so as to enable the intersection region of the multipath current signals on the stimulated object to generate difference frequency signals.
In a further optimization scheme, the signal generation module comprises a waveform generator and a Holland current pump; the waveform generator generates sine wave digital signals through built-in data through calculation, and transmits the sine wave digital signals to a digital-to-analog converter; the Holland current pump forms a sinusoidal current with a specific current size by reading an analog signal converted by the digital-to-analog converter.
In the further optimization scheme, the signal generation module firstly outputs 3 paths of sine waves to 3 groups of following circuits through a 3-digital-to-analog converter of a single chip microcomputer of STM32, then outputs the sine waves to a Holland current pump through the 3 groups of following circuits, and finally generates a required waveform through the Holland current pump.
In order to stabilize the output current, a Howland current pump is adopted to output a desired electrical interference signal. The Holland current pump comprises an operational amplifier, an amplifier and a digital potentiometer. The model of the operational amplifier is AD8630, the models of the amplifiers are INA592 and OPA4197, and the model of the digital potentiometer is AD 5235. This circuit uses a sinusoidal signal and a set of SPI communications to control the output of the electrical interference signal. All circuits adopt one-ten-thousandth precision resistors, so that the output current is more precise, and the device can be normally used for stimulation under the condition that the skin is not grounded.
According to a further optimization scheme, the user interaction module comprises a screen; the screen is used for receiving the electric interference parameters input by a user and displaying the electric interference information and the impedance value in real time.
The user interaction module is formed by controlling a capacitive touch screen by an STM32 singlechip in a serial port communication mode, wherein two groups of XH2.54 PINs are used as interfaces for connecting a power supply, a 4PIN FPC is used as an interface for serial port signal communication and is connected to the touch screen, a 4PPIN FPC is used as an interface for an SPI communication protocol and is connected to a signal generation module, and a CAN port is used as an interface for external communication to form all external communication interfaces of the whole circuit board. The 12V voltage is converted into the stable 3.3V voltage by the LP2985 to supply power to the singlechip.
In a further optimization scheme, the impedance detection module comprises an impedance detection system; the impedance detection system inputs the voltage generated by the current input to the skin into the analog-to-digital converter through the processing of the following circuit and the voltage division circuit; the digital signal is transmitted to a central processing unit by an analog-to-digital converter to calculate an impedance value; and feeding back the real-time calculated impedance value to the user interaction interface.
In a further optimization scheme, the impedance detection module is a signal processing circuit consisting of a group of attenuation circuits and operational amplifier circuits. And then the signal processing circuit is connected to an ADC port of an STM32 singlechip. The ADG1421 is a set of multiplexers, and different resistors can be selected to reduce the voltage of the acquired signal to ± 1.65V by means of resistor division. Then the AD8253 instrument amplifier and a group of pull-up resistors change the signal of +/-1.65V into a signal of 0-3.3V and input the signal into the ADC.
According to a further optimization scheme, the signal output module comprises a pair of electrodes connected with each output interface; at least two pairs of the electrodes are arranged at the stimulated part of the stimulated object; each pair of electrodes has a group of impedance detection functions, and the skin impedance can be checked in real time.
In a further optimization scheme, one group of signal output modules of the signal output modules consists of three silver disc electrodes. Two of the output electrodes are connected near the corresponding target points, and one of the ground electrodes is connected to the abdomen of the user.
In a further optimized scheme, the difference frequency electric interference equipment further comprises a shell; the user interaction module, the impedance detection module and the signal generation module are all arranged in the shell, and the signal output module is arranged outside the shell.
The further optimization scheme is that the difference frequency electric interference system further comprises an upper computer; and the upper computer is in communication connection with the difference frequency electric interference equipment.
A method of difference frequency electrical interference, the method comprising: acquiring stimulation parameters sent by the difference frequency electrical interference equipment, and determining electrode combinations corresponding to the stimulation parameters; acquiring the impedance of a stimulated object sent by the difference frequency electrical interference equipment, and judging whether the electrode combination is qualified in connection or not according to the impedance of the stimulated object; when the electrode combination is qualified in connection, acquiring electric field information sent by the difference frequency electric interference equipment; and inputting the electric field information into an electric field model corresponding to the electrode combination to obtain and display an electric field dynamic image in real time.
In a further optimization scheme, the method further comprises the following steps: in the process of electric interference, acquiring and displaying the impedance of the stimulated object in real time, and monitoring whether the electrode combination is qualified in connection or not according to the impedance of the stimulated object; when the electrode combination is qualified in connection, receiving electrical interference information sent by the difference frequency electrical interference equipment; recording experimental data of the stimulated object according to the electrical interference information, and displaying the electrical interference information in real time; and when the electrode combination connection is unqualified, sending out an alarm prompt.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, are merely for convenience of description of the present invention, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
The above-described embodiments are merely illustrative of the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various modifications and improvements of the technical solutions of the present invention can be made by those skilled in the art without departing from the spirit of the present invention, and the technical solutions of the present invention are within the scope of the present invention defined by the claims.
Claims (9)
1. A difference frequency electrical interference apparatus, comprising: the system comprises a user interaction module, a signal generation module, an impedance detection module and a signal output module which are connected in sequence;
the user interaction module is used for transmitting the setting parameters of the electric interference signals to the signal generation module according to the requirements input by the receiving user;
the signal generating module is used for generating a plurality of paths of current signals with different frequencies according to the received parameters and sending the current signals to the signal output module;
the impedance detection module is used for collecting current signals of each pair of electrodes and calculating to obtain a real-time impedance value;
the signal output module is used for transmitting the multipath current signals to a plurality of corresponding pairs of electrodes through a plurality of output interfaces so as to enable the intersection region of the multipath current signals on the stimulated object to generate difference frequency signals.
2. The difference frequency electrical interference apparatus of claim 1, wherein: the signal generation module comprises a waveform generator and a Holland current pump; the waveform generator generates sine wave digital signals through built-in data through calculation and transmits the sine wave digital signals to the digital-to-analog converter; the Holland current pump forms a sinusoidal current with a specific current size by reading an analog signal converted by the digital-to-analog converter.
3. The difference frequency electrical interference apparatus of claim 1, wherein: the user interaction module comprises a screen; the screen is used for receiving the electric interference parameters input by a user and displaying the electric interference information and the impedance value in real time.
4. The difference frequency electrical interference apparatus of claim 1, wherein: the impedance detection module comprises an impedance detection system; the impedance detection system inputs the voltage generated by the current input to the skin into the analog-to-digital converter through the processing of the following circuit and the voltage division circuit; the digital signal is transmitted to a central processing unit by an analog-to-digital converter to calculate an impedance value; and feeding back the real-time calculated impedance value to the user interaction interface.
5. The difference frequency electrical interference apparatus of claim 1, wherein: the signal output module comprises a pair of electrodes connected with each output interface; at least two pairs of the electrodes are arranged at the stimulated part of the stimulated object; each pair of electrodes has a group of impedance detection functions, and the skin impedance can be checked in real time.
6. The difference frequency electrical interference apparatus of claims 1-5, characterized by: the difference frequency electrical interference device further comprises a housing; the user interaction module, the impedance detection module and the signal generation module are all arranged in the shell, and the signal output module is arranged outside the shell.
7. A difference frequency electrical interference system, comprising: the difference frequency electric interference device of any one of the preceding claims 1-6, further comprising an upper computer; and the upper computer is in communication connection with the difference frequency electric interference equipment.
8. A method of differential frequency electrical interference, comprising: upper computer software for use in a difference frequency electrical interference system according to claim 7, comprising the steps of: acquiring stimulation parameters sent by the difference frequency electrical interference equipment, and determining electrode combinations corresponding to the stimulation parameters; acquiring the impedance of a stimulated object sent by the difference frequency electrical interference equipment, and judging whether the electrode combination is qualified in connection or not according to the impedance of the stimulated object; when the electrode combination is qualified in connection, acquiring electric field information sent by the difference frequency electric interference equipment; and inputting the electric field information into an electric field model corresponding to the electrode combination to obtain and display an electric field dynamic image in real time.
9. The method of claim 8, further comprising: in the process of electric interference, acquiring and displaying the impedance of the stimulated object in real time, and monitoring whether the electrode combination is qualified in connection or not according to the impedance of the stimulated object; when the electrode combination is qualified in connection, receiving electrical interference information sent by the difference frequency electrical interference equipment; recording experimental data of the stimulated object according to the electrical interference information, and displaying the electrical interference information in real time; and when the electrode combination connection is unqualified, sending out an alarm prompt.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911267110.3A CN110917496A (en) | 2019-12-11 | 2019-12-11 | Difference frequency electric interference equipment, system and method |
| PCT/CN2020/114070 WO2021114778A1 (en) | 2019-12-11 | 2020-09-08 | Differential frequency electrical interference device, system, and method |
| CH000675/2022A CH718300B1 (en) | 2019-12-11 | 2020-09-08 | Apparatus and system for generating differential frequency electrical interference. |
| ZA2022/05655A ZA202205655B (en) | 2019-12-11 | 2022-05-23 | Difference frequency electrical interference device, system and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911267110.3A CN110917496A (en) | 2019-12-11 | 2019-12-11 | Difference frequency electric interference equipment, system and method |
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| Publication Number | Publication Date |
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| CN110917496A true CN110917496A (en) | 2020-03-27 |
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| CN201911267110.3A Pending CN110917496A (en) | 2019-12-11 | 2019-12-11 | Difference frequency electric interference equipment, system and method |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN110917496A (en) |
| CH (1) | CH718300B1 (en) |
| WO (1) | WO2021114778A1 (en) |
| ZA (1) | ZA202205655B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112315445A (en) * | 2020-11-11 | 2021-02-05 | 深圳市因特迈科技有限公司 | Wearable sweat monitoring device |
| WO2021114778A1 (en) * | 2019-12-11 | 2021-06-17 | 北京理工大学 | Differential frequency electrical interference device, system, and method |
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| CN102686272A (en) * | 2009-11-30 | 2012-09-19 | 罗伯特·莱 | Device for electrotherapeutic treatment |
| CN107261329A (en) * | 2017-01-26 | 2017-10-20 | 中国医学科学院生物医学工程研究所 | Electrical stimulation device and method based on difference frequency ultrasound and inverse magnetosonic coupling technique |
| CN108310639A (en) * | 2018-03-07 | 2018-07-24 | 北京大智商医疗器械有限公司 | Difference frequency electrical stimulation apparatus, system and method |
| US10322294B2 (en) * | 2005-01-21 | 2019-06-18 | Michael Sasha John | Systems and methods for vector stimulation in medical treatment |
| CN110200628A (en) * | 2019-05-13 | 2019-09-06 | 南京航空航天大学 | A kind of portable impedance detection system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN209154887U (en) * | 2018-03-07 | 2019-07-26 | 北京大智商医疗器械有限公司 | Difference frequency electrical stimulation apparatus and system for animal experiment |
| CN209154888U (en) * | 2018-03-07 | 2019-07-26 | 北京大智商医疗器械有限公司 | Difference frequency electrical stimulation apparatus and system |
| CN108671389A (en) * | 2018-04-25 | 2018-10-19 | 中国人民解放军军事科学院军事医学研究院 | Multi-mode is wearable through cranium electric current stimulating apparatus |
| CN110917496A (en) * | 2019-12-11 | 2020-03-27 | 北京理工大学 | Difference frequency electric interference equipment, system and method |
-
2019
- 2019-12-11 CN CN201911267110.3A patent/CN110917496A/en active Pending
-
2020
- 2020-09-08 CH CH000675/2022A patent/CH718300B1/en unknown
- 2020-09-08 WO PCT/CN2020/114070 patent/WO2021114778A1/en active Application Filing
-
2022
- 2022-05-23 ZA ZA2022/05655A patent/ZA202205655B/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US10322294B2 (en) * | 2005-01-21 | 2019-06-18 | Michael Sasha John | Systems and methods for vector stimulation in medical treatment |
| CN102686272A (en) * | 2009-11-30 | 2012-09-19 | 罗伯特·莱 | Device for electrotherapeutic treatment |
| CN107261329A (en) * | 2017-01-26 | 2017-10-20 | 中国医学科学院生物医学工程研究所 | Electrical stimulation device and method based on difference frequency ultrasound and inverse magnetosonic coupling technique |
| CN108310639A (en) * | 2018-03-07 | 2018-07-24 | 北京大智商医疗器械有限公司 | Difference frequency electrical stimulation apparatus, system and method |
| CN110200628A (en) * | 2019-05-13 | 2019-09-06 | 南京航空航天大学 | A kind of portable impedance detection system |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021114778A1 (en) * | 2019-12-11 | 2021-06-17 | 北京理工大学 | Differential frequency electrical interference device, system, and method |
| CN112315445A (en) * | 2020-11-11 | 2021-02-05 | 深圳市因特迈科技有限公司 | Wearable sweat monitoring device |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021114778A1 (en) | 2021-06-17 |
| ZA202205655B (en) | 2022-10-26 |
| CH718300B1 (en) | 2023-06-15 |
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