CN1108951A - Antiphlogistic and sterilizing disinfectant and its preparation - Google Patents
Antiphlogistic and sterilizing disinfectant and its preparation Download PDFInfo
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- CN1108951A CN1108951A CN 94117551 CN94117551A CN1108951A CN 1108951 A CN1108951 A CN 1108951A CN 94117551 CN94117551 CN 94117551 CN 94117551 A CN94117551 A CN 94117551A CN 1108951 A CN1108951 A CN 1108951A
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- rhizoma
- radix
- sophorae flavescentis
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- total alkaloids
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Abstract
An antiphlogistic and sterilizing disinfectant used as skin or mucosa medicine and for stopping itch, haemostasis, insecticiding, and sterilication and fresh-keeping for fruit and vegetables is prepared with more than 10 Chinese-medicinal components through decoction, alcohol extraction and decolouring by activated carbon, and features broad-spectrum disinfecting and no toxic side-effect.
Description
The present invention relates to a kind of is medical antiinflammatory, sterilization, antibacterial and the production method thereof of feedstock production with the several kinds of Chinese medicinal materials.It can be done medical treatment and go up skin, mucosa medication, also can be used for the sterilization to the articles for daily use, people and animals' environment.
A kind of ideal disinfectant should all have pathogen such as antibacterial, fungus, virus, protozoon, spirillums simultaneously to be killed or inhibitory action reliably, and it is with low cost, easy to use, can extensive use, and human body do not had ill effect.Existing multiple disinfectant all can not reach ideal degree, and the scope of perhaps killing pathogen is wide inadequately, perhaps to human body, environment is had certain damaging effect.Simultaneously, the pathogen meeting developmental biology variation as the dissipation object produces adaptation and resistance to original disinfectant, even the effect of original disinfectant just weakens disappearance relatively.Therefore, constantly seek the task that new disinfectant reliable for effect just becomes medical hygiene circle.The disinfectant that particularly has tangible antiinflammation simultaneously is the needs in the medical treatment especially.
The objective of the invention is to, a kind of medicament with obvious antiinflammation and broad-spectrum bactericidal action is provided.It produces (to call the anti-inflammation and sterilization agent in the following text) easily, and is easy to use, kills the reliable for effect of pathogen, can do medical treatment and go up skin, mucosa medication, and human body is had no side effect.
Can solve in order to following method by this task of the present invention.
One medicament composing prescription and its weight are formed
1. medicament composing prescription
The agent of this anti-inflammation and sterilization is Main Ingredients and Appearance with the Radix Sophorae Flavescentis total alkaloids, is aided with the extract of multiple Chinese herbal medicine.Its prescription is Radix Sophorae Flavescentis total alkaloids, Rhizoma Coptidis, Foliumet Ramulus Evodiae, Tradescantia albiflora, Herba Violae, Radix Isatidis, Rhizoma Belamcandae, Radix Arnebiae (Radix Lithospermi), Cortex Fraxini, Rhizoma Acori Graminei, Semen Hydnocarpi, Herba Chenopodii, Rhizoma Polygoni Cuspidati, the Pseudobulbus Bletillae (Rhizoma Bletillae), Folium Eucalypti Robustae, totally 15 kinds of crude drug.
Can remove Foliumet Ramulus Evodiae and two kinds of crude drug of Rhizoma Belamcandae in the above prescription and keep the key property of medicine.
2. drug weight is formed
The percentage by weight of 15 kinds of crude drug is, Radix Sophorae Flavescentis total alkaloids 15～20,14 kinds of crude drug such as all the other each medicine-Rhizoma Coptidis, Foliumet Ramulus Evodiae, Tradescantia albiflora, Herba Violae, Radix Isatidis, Rhizoma Belamcandae, Radix Arnebiae (Radix Lithospermi), Cortex Fraxini, Rhizoma Acori Graminei, Semen Hydnocarpi, Herba Chenopodii, Rhizoma Polygoni Cuspidati, the Pseudobulbus Bletillae (Rhizoma Bletillae), Folium Eucalypti Robustae respectively account for 5.5～6.5.
Two production methods
1. by this product recipe quantity all crude drug except that Radix Sophorae Flavescentis total alkaloids are mixed, decoct three times.To add water an amount of at every turn, boils about 30 minutes, and it is standby to cross the leaching decoction liquor.
2. decoct filtrates merging with above-mentioned three times, add Radix Sophorae Flavescentis total alkaloids while hot, stir or boiled 2～5 minutes, Radix Sophorae Flavescentis total alkaloids is fully dissolved, adjusting amount of liquid medicine to per 100 milliliters of medicinal liquids, to contain the crude drug equivalent be about 10 grams, cools off fast or put cold.
3. 95% ethanol with 4～5 times of amounts adds in the above-mentioned medicinal liquid, leaves standstill 24 hours after fully stirring, and filters, and reclaims ethanol, water intaking solution.
4. getting active carbon by 0.5～1.0%(W/V) adds in the above-mentioned medicinal liquid, boil, be incubated 30 minutes, charcoal is taken off in filtration, and it is 2.5～5.2 grams that adding distil water adjustment amount of liquid medicine to per 100 milliliters of medicinal liquids contain the crude drug equivalent, leaves standstill more than 48 hours, filter, the obtained aqueous solution outward appearance is brown or rose-colored deeply, and pH value is 7.2-8.0, is this anti-inflammation and sterilization agent finished product.
Embodiment is following, and the invention will be further described with the example of producing 10000 milliliters of anti-inflammation and sterilization agent.
1. measure Rhizoma Coptidis 30 grams, Foliumet Ramulus Evodiae 30 grams, Tradescantia albiflora 30 grams, Herba Violae 30 grams, Radix Isatidis 30 grams, Rhizoma Belamcandae 30 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Cortex Fraxini 30 grams, Rhizoma Acori Graminei 30 grams, Semen Hydnocarpi 30 grams, Herba Chenopodii 30 grams, Rhizoma Polygoni Cuspidati 30 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 30 grams, Folium Eucalypti Robustae 30 grams by this product prescription, mix, decoct three times, to add water an amount of at every turn, boiled respectively 40 minutes, 30 minutes, 20 minutes, it is standby to cross the leaching decoction liquor respectively.
2. the filtrate that decocts for above-mentioned three times is merged, add Radix Sophorae Flavescentis total alkaloids 100 grams while hot, boiled 3 minutes, adjust amount of liquid medicine to 5000 milliliter, put cold.
3. add 20000 milliliters of 95% ethanol in cooled medicinal liquid, left standstill 24 hours after fully stirring, filter, ethanol is reclaimed in distilling under reduced pressure.
4. 25 gram active carbons are added in the above-mentioned medicinal liquid, boil, be incubated 30 minutes, filter and to take off charcoal, adding distil water to 10500 milliliter, leave standstill 50 hours after, filtration, the gained amount of liquid medicine is 10000 milliliters, is this anti-inflammation and sterilization agent finished product, packing is stand-by.
It is 5.2%(W/V that the agent of present embodiment gained finished product anti-inflammation and sterilization contains the crude drug ratio), outward appearance is brown, pH value is 7.4.
Anti-inflammation and sterilization agent of the present invention shows still pathogen such as antibacterial, fungus, virus, protozoon, spirillum are had and kill reliably or inhibitory action behind the dilution several times through the antibacterial activity in vitro test; Through clinical 315 routine gynecological, cutaneous diseases patient treatment are observed, can be promoted that slough comes off, granulation tissue is grown, the wound immediate union.Have hemostasis simultaneously, cease functions such as pain is antipruritic, parasite killing delousing, human body is not found toxicity, zest and anaphylactic reaction.
The purposes of this anti-inflammation and sterilization agent: 1. surgery, gynecological, department of dermatologry, department of eye belong to the treatment of mucosa, scytitis and wound; 2. making sanltary towel, napkin, hand towel etc. has the articles for use of sterilization; 3. the sterilization of roofing, air, equipment and various the articles for daily uses in people and animals' environment; 4. fruit, Vegetable Preservation; 5. other need make the purposes that sterilizing is handled.
This anti-inflammation and sterilization agent using method: 1. directly embrocate the human body affected part; 2. dilution back washout or demibain; 3. environment is sprayed, equipment and apparatus are cleaned; 4. the dilution back is to the room air spraying disinfection; 5. soak fruit, vegetable in order to fresh-keeping.
Not seeing as yet with the matrine from present domestic and foreign literature and commercial goods is the disinfectant of Main Ingredients and Appearance preparation." JIEERYIN ", the application number that grace prestige generation prosperous pharmaceutical Co. Ltd in Chengdu produces is 93110896.9, publication number be the disclosed medicaments such as " powder medicine for wound and ulcer and manufacture methods thereof " of CN 1080866A employed all are the former medicines of Radix Sophorae Flavescentis.The present invention is different with above medicament, except that on the prescription of medicine, having the tangible difference, prior being, the present invention is the Main Ingredients and Appearance of anti-inflammation and sterilization agent with the active ingredient-Radix Sophorae Flavescentis total alkaloids of Radix Sophorae Flavescentis, easier preparation, its anti-inflammation and sterilization effect is more reliable, and can accurately adjust the consumption of Radix Sophorae Flavescentis total alkaloids according to different purposes.
Claims (3)
1, a kind of antiinflammatory, sterilization, antibacterial, it is Main Ingredients and Appearance with the Radix Sophorae Flavescentis total alkaloids, the extract that is aided with multiple Chinese herbal medicine is formulated, it is characterized in that its prescription is 15 kinds of crude drug such as Radix Sophorae Flavescentis total alkaloids, Rhizoma Coptidis, Foliumet Ramulus Evodiae, Tradescantia albiflora, Herba Violae, Radix Isatidis, Rhizoma Belamcandae, Radix Arnebiae (Radix Lithospermi), Cortex Fraxini, Rhizoma Acori Graminei, Semen Hydnocarpi, Herba Chenopodii, Rhizoma Polygoni Cuspidati, the Pseudobulbus Bletillae (Rhizoma Bletillae), Folium Eucalypti Robustae.
2, antiinflammatory according to claim 1, sterilization, antibacterial, it is characterized in that, the percentage by weight of prescription crude drug is, Radix Sophorae Flavescentis total alkaloids 15～20,14 kinds of crude drug such as all the other each medicine-Rhizoma Coptidis, Foliumet Ramulus Evodiae, Tradescantia albiflora, Herba Violae, Radix Isatidis, Rhizoma Belamcandae, Radix Arnebiae (Radix Lithospermi), Cortex Fraxini, Rhizoma Acori Graminei, Semen Hydnocarpi, Herba Chenopodii, Rhizoma Polygoni Cuspidati, the Pseudobulbus Bletillae (Rhizoma Bletillae), Folium Eucalypti Robustae respectively account for 5.5～6.5.
3, antiinflammatory according to claim 1, sterilization, antibacterial is characterized in that, its preparation method is with all crude drug mixing decoctions except that Radix Sophorae Flavescentis total alkaloids, to get decoction liquor and filter, the adding Radix Sophorae Flavescentis total alkaloids; 95% ethanol that the cooling back adds 4～5 times of amounts left standstill 24 hours, filtered once more, reclaimed ethanol; By 0.5～1.0% adding active carbon, boil, be incubated 30 minutes, filter and take off charcoal, it is 2.5～5.2 grams that adding distil water adjustment amount of liquid medicine to per 100 milliliters of medicinal liquids contain the crude drug equivalent, leaves standstill more than 48 hours filtration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94117551 CN1108951A (en) | 1994-10-31 | 1994-10-31 | Antiphlogistic and sterilizing disinfectant and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94117551 CN1108951A (en) | 1994-10-31 | 1994-10-31 | Antiphlogistic and sterilizing disinfectant and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1108951A true CN1108951A (en) | 1995-09-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 94117551 Pending CN1108951A (en) | 1994-10-31 | 1994-10-31 | Antiphlogistic and sterilizing disinfectant and its preparation |
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| CN (1) | CN1108951A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631693A (en) * | 2012-05-04 | 2012-08-15 | 柳州华力家庭品业股份有限公司 | Chinese herbal medicine aerosol for removing formaldehyde and peculiar smells and preparation method of Chinese herbal medicine aerosol |
| CN103141567A (en) * | 2013-03-27 | 2013-06-12 | 王金玉 | Litchi chinensis preservative based on Chinese medicinal herbs and preparation method thereof |
| CN104491555A (en) * | 2015-01-06 | 2015-04-08 | 杭州小姐妹卫生用品有限公司 | Disinfectant and hemostatic wet tissue and preparation method thereof |
| CN106421191A (en) * | 2016-08-31 | 2017-02-22 | 尹明义 | Traditional Chinese patent medicine for treating skin itch and preparation method thereof |
-
1994
- 1994-10-31 CN CN 94117551 patent/CN1108951A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631693A (en) * | 2012-05-04 | 2012-08-15 | 柳州华力家庭品业股份有限公司 | Chinese herbal medicine aerosol for removing formaldehyde and peculiar smells and preparation method of Chinese herbal medicine aerosol |
| CN102631693B (en) * | 2012-05-04 | 2014-04-30 | 柳州华力家庭品业股份有限公司 | Chinese herbal medicine aerosol for removing formaldehyde and peculiar smells and preparation method of Chinese herbal medicine aerosol |
| CN103141567A (en) * | 2013-03-27 | 2013-06-12 | 王金玉 | Litchi chinensis preservative based on Chinese medicinal herbs and preparation method thereof |
| CN104491555A (en) * | 2015-01-06 | 2015-04-08 | 杭州小姐妹卫生用品有限公司 | Disinfectant and hemostatic wet tissue and preparation method thereof |
| CN106421191A (en) * | 2016-08-31 | 2017-02-22 | 尹明义 | Traditional Chinese patent medicine for treating skin itch and preparation method thereof |
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