CN1108785C

CN1108785C - Skin care composition

Info

Publication number: CN1108785C
Application number: CN97193727A
Authority: CN
Inventors: Z·纳瓦茨; E·欧文
Original assignee: Procter and Gamble Co
Current assignee: Procter and Gamble Co
Priority date: 1996-03-05
Filing date: 1997-02-19
Publication date: 2003-05-21
Anticipated expiration: 2017-02-19
Also published as: EP0884996A1; CN1215324A; GB9604674D0; KR100299499B1; AU726435B2; WO1997032560A1; KR19990087558A; CZ284098A3; JP3621112B2; JPH11506125A; AU2130197A; EP0884996A4; CA2247825A1

Abstract

A skin care composition in the form of an oil-in-water emulsion comprising: (a) from about 0.1 % to about 10 % by weight of a particulate component having an average particle size of about 50 microns or less; (b) from about 0.1 % to about 20 % by weight of an organic liquid crystal-forming amphiphilic surfactant; (c) emulsified oil phase; and (d) water. The compositions of the invention provide improved skin feel, reduced greasiness/stickiness and faster absorption.

Description

Skin care compositions

Technical field

The present invention relates to cosmetic composition, relate to the cosmetic composition of emulsion form especially, it provides improved humidification, dermal sensation, and skin protection, the oils and fats of outward appearance benefit and reduction and excellent rubbing are wiped and are infiltrated and absorption characteristic.Under room temperature and temperature rising situation, compositions also shows excellent stability.

Background of invention

Skin is made up of several cellular layers, and its covering and protection form the keratin and the collagen fiber albumen of skin texture skeleton.The outermost layer of these cellular layers is called horny layer, and known is the protein Shu Zucheng of 25 nanometers that is surrounded by the thick-layer of 8 nanometers by skin.Anion surfactant and organic solvent infiltrate the cutin tunic usually and destroy its integrity by degreasing (sloughing the class ester in the horny layer).This skin surface structural damage causes harsh feeling and may finally make surfactant or solvent and keratin reaction, produces pain.

Suitable water content gradient is important to its function in the now cognitive maintenance horny layer.Most water is considered to cuticular flexibility agent sometimes, comes from the body.If humidity is too low,, there is not adequate moisture to keep organizing normal pliability, skin will become squamous and producing Pruritus in outer layer of stratum corneum as at cold day.When cuticular moisture content was inadequate, percutaneous permeability also had certain reduction.On the other hand, the too many moisture content of skin outer layer will cause horny layer finally to absorb the 3-5 doubly knot and the water of himself weight.This makes puffiness of skin wrinkling, causes skin that the permeability of moisture content or other polar molecule is approximately increased by 2 to 3 times.

Need compositions like this, although it is in washing, the deleterious interaction that runs in work and the amusement still can help horny layer to keep its barrier and water retaining function is in optimum state.

Traditional cosmetic emulsion and detergent composition in the document, for example, " Sagarin cosmetic science and technology ", the 2nd edition, volume 1, Wiley Interscience publishes (1972) and " encyclopedia of chemical technology ", the third edition, in the volume 7, the known skin moistening in various degree that provides, the advantage of barrier and water conservation (humidification).Yet also there is serious adverse (being that skin often feels greasy) in they and has relatively poor rubbing to wipe aspect dermal sensation infiltrates and persistence characteristic, and skin absorbs is very slow.

Therefore, still need a kind of compositions, it can help horny layer to keep its gradation of moisture, but have again simultaneously improvement skin feel, rub and wipe accessibility and persistence characteristic and skin absorption.

The known chemical compound that will embody liquid crystal property is used for skin care compositions.Liquid crystal is a kind of special material phase.Liquid crystalline phase is between solid-state and isotropic liquid state (i.e. intermediate state between the crystal state of three-dimensional order and unordered dissolved state).During liquid crystal state, because molecule association structure and long-range is intermolecular makes that in order the molecular assembly characteristic of some solid phase is kept in liquid state.The ability that some chemical compound can form the liquid crystal mesomorphic phase is found before a century.From then on, synthesized the chemical compound of many embodiment liquid crystal properties, and be used for entrapped drug, flavoring agent, nutrient and other chemical compound and be used as their delivery vehicles and be used for skin care compositions.

Known pigment/the colorant that will be used as such as the granule of silicon dioxide, titanium dioxide and zinc oxide in the cosmetics, and benefit such as uv absorption and oil absorption is provided.But still need and reduce on the viscosity of skin/greasy and improve at skin feel, skin absorbs speed.

Shockingly find now, by in the cosmetic emulsion compositions, adding material and the about 50 μ m of mean diameter or the lower grain fraction that can form liquid crystal, a kind of compositions that strengthens wettability and skin feel can be provided, and said composition especially produces faster absorption and has reduced the viscosity and the greasy feeling of skin.

Summary of the invention

According to an aspect of the present invention, provide the skin care compositions of O/w emulsion form, it comprises:

(a) from about 0.1% to about 10% heavy particulate component, its mean diameter is about 50 μ m or lower;

(b) from about 0.1% to about 20% heavy organic amphiphilic surfactant that can form liquid crystal;

(c) emulsive oil phase; With

(d) water.

According to another aspect of the present invention, provide retention type humidification emulsion, it comprises:

(b) emulsive oil phase; With

(c) water.

Compositions of the present invention provides the skin feel of improvement, and the greasy/viscosity of reduction and absorption are faster.

In accordance with a further aspect of the present invention, provide a kind of cosmetic method of handling skin, wherein this method comprises to dermal administration skin care compositions of the present invention.

Detailed Description Of The Invention

Compositions of the present invention exists with the form of O/w emulsion, and it comprises one or more different emulsifying oil phases and a kind of basic one-tenth liquid crystal emulsifier component, and multiple non-essential composition as follows.The present composition also contains the basis particulate component, and its mean diameter is 50 μ m or lower.Unless indicate in addition, all content and ratio are all by the weight of whole compositionss.The degree of chain length and ethoxylation also indicates on the weight average basis.

The term of Shi Yonging " skin conditioning agent " means a kind of material with " conditioning skin advantage " herein.Here, term " conditioning skin advantage " means any cosmetic conditioning benefit to skin, include but are not limited to humidification, moisture-keeping function (be about to water or moisture keep or remain on ability in the skin), skin moistening effect, improve skin surface visual sense of beauty, make skin comfortable, make the skin softness, improve skin feel and similar function.

The term of Shi Yonging " fusing point fully " means the fusing point that records with the differential scanning calorimetry of knowing (DSC) herein.Fully fusing point is that baseline is promptly than the temperature of the intersection point of hot line and endothermic peak afterbody tangent line.Adopt 5 ℃/minute scanning temperature when measuring fine melt point among the present invention.But, should be realized that under particular environment this area analytical chemistry personnel may think that rate of scanning is suitable faster.A kind of technology that measures fine melt point licenses to people's such as Letton U.S.P.No.5 on April 26th, 1994, description is also arranged in 306,514, and its content is all quoted as a reference at this.

The term of Shi Yonging " non-occlusive " means described material and is not plugged in the penetrating of the air of skin surface and moisture basically herein.

First basis of the compositions here is particulate component, the about 50 μ m or lower of its mean diameter, preferred about 30 microns or lower, more preferably from about 10 microns or lower.Usually the preferred mean diameter of particulate component is at least about 0.5 micron, more preferably at least about 1 micron, and most preferably from about 2 to about 8 microns.Usually, the granule that adopts here is preferably inert.Here 'inertia' is meant that they only have limited chemical reaction ability.Found that particulate component is especially valuable for the application properties of improving skin feel and retention type humidification emulsion.Therefore, according to a further aspect in the invention, provide a kind of retention type humidification emulsion, it comprises:

(b) emulsive oil phase; With

(c) water.

Particulate component content is about 0.1% to about 10% in the said composition, and preferred about 0.5% to about 5% weight.

Here the particulate matter of Shi Yonging comprises the inorganic and organic particulate matter that is applicable to skin care compositions, this class particulate matter comprises inorganic, metal oxide or nitride, as zinc oxide, titanium dioxide, iron oxides and boron nitride, plastic particle, as low density polyethylene (LDPE), high density polyethylene (HDPE), polypropylene, nylon, polytetrafluoroethylene, the nylon that collagen is handled and based on the spherolite of methacrylate, organic granular, as starch, flour, the silk powder, starch ocentyl succinic aluminum, esters, as N-lauryl-l-lysine and silicon derivatized particles, as Muscovitum, silicon dioxide, Silicon stone and magnesium silicate/aluminium silicate.

From improving the angle of skin feel and application properties, preferably adopt inorganic, metal oxide and plastic particle here.In preferred embodiments, grain fraction is selected from: silicon dioxide, polyethylene and composition thereof.In especially preferred embodiment, particulate matter is silicon dioxide and poly mixture, and its weight ratio is about 3: 1 to about 1: 3, preferred about 2: 1 to about 1: 2.

Here preferred polyethylene is a low density polyethylene (LDPE), as the product of being sold with trade name Flo-Beads level LE-1080 by Sumitomo Seika chemistry company limited.The mean diameter of this material is about 6 microns.Here preferred silica dioxide granule thing is silica beads SB-300, is prepared by CosmoTrends company.

Amphiphilic surfactant

Another solvent of the present composition is organic amphiphilic surfactant, can form the molten smectic type crystal that causes when it is applied on the skin in product or under room temperature or the higher temperature.Preferred amphiphilic substance can form liquid crystal at about 20 ℃ to about 40 ℃ of scopes.Preferred amphiphilic surfactant can form the molten smectic crystal that causes.In case after being applied in product on the skin, in skin surface or horny layer, may can not identify liquid crystal.The content of amphiphilic substance is about 0.1% to about 20%, and preferred about 0.1% to about 10% weight.

The amphiphilic substance that is applicable to this formation liquid crystal contains hydrophilic and two kinds of groups of oleophylic, and obviously embodies the trend (being that they are surface-active) that is adsorbed on surface or the interface.Here the amphiphilic surface active substance of Cai Yonging comprises nonionic (neutral), anionic (electronegative), cationic (positively charged) and amphoteric (band positive and negative electric charge), and whether this produces ionization based on them in aqueous medium.

In the literature, liquid crystal is also referred to as the 4th attitude, surfactant associative structure or the mesomorphic phase of anisotropic fluid, material.These terms are used alternatingly usually.Here term " molten causing " is meant the liquid crystal system that contains polar solvent such as water.Here used liquid crystal is preferably stratiform, six squares, bar-shaped or cystic structures or its mixed structure.

The liquid crystalline phase that adopts in the present composition can be differentiated with different modes.Liquid crystalline phase is being sheared current downflow and is being characterised in that its viscosity obviously is different from the viscosity of its isotropic solution phase.Rigid gel can not sheared current downflow as liquid crystal.Equally, when observing with polarizing microscope, liquid crystal illustrates identifiable birefringence, as plane stratiform birefringence, but when isotropic aqueous solution and rigid gel are observed, all shows the visual field of black under polarisation.

Other proper method of differentiating liquid crystal comprises X-ray diffraction, NMR spectrum and transmission electron microscope.

Usually, the preferred here organic amphiphilic substance that uses can be described as liquid state, semisolid or the dispersible material of waxy water, and it has formula X-Y, and wherein the X representative is hydrophilic, especially non-ionic part, and Y represents oleophilic moiety.

The organic amphiphilic substance that is applicable to this comprises those weight averages HLB (hydrophile-lipophile balance value) about 2 to about 12, preferred about 4 to about 8 material.

Here the oleophylic chain that the preferred organic amphiphilic substance that adopts has long saturated or unsaturated branching or line style, this chain has about 12 to about 30 carbon atoms, as oil base, lanoline base, tetradecyl, palmityl, iso stearyl, lauryl, cocoa base, stearyl or alkyl phenyl chain.When the hydrophilic group of the amphiphilic substance that forms liquid crystalline phase is non-ionic group, can adopt polyoxyethylene, polyglycols, polyol ester (can or not alkoxylate) and for example poly-alkoxylation sorbitol or sugar ester.When the hydrophilic group of the amphiphilic substance that forms liquid crystalline phase is ionic group, preferably be adopted as the phosphatidylcholine residue that having of hydrophilic group found in lecithin.

Here the preferred hydrophilic segment that adopts is selected from:

(1) have the ether of polyglycols line style or branching of following general formula:

R-(Gly) _n-OH

Wherein n is the integer between 1 to 6, and that R is selected from is aliphatic series, line style or branching, saturated or undersaturated, the chain with 12 to 30 carbon atoms, the alkyl of lanolin alcohol and the 2-hydroxy alkyl residue of long-chain salmefamol, and Gly represents diol residue;

(2) polyethoxylated aliphatic alcohol for example has formula R ¹(C ₂R ₄O) _xThose of OH, wherein R ¹Be the alkyl or alkenyl of C12-C30 line style or branching, X on average about 0 is to about 20, and preferred about 0.1 to about 6, and more preferably from about 1 to about 4;

(3) polyol ester of polyol ester and poly-alkoxylation and composition thereof, polyhydric alcohol is preferably from sugar, C2-C6 aklylene glycol, glycerol, polyglycereol, sorbitol, anhydro sorbitol, Polyethylene Glycol and polypropylene glycol, wherein the polyol ester of poly-alkoxylation contains every mole of polyol ester about 2 to about 20, and preferred about 2 to about 4 moles alkylene oxide (especially oxirane).

(4) natural or synthetic phosphoglyceride, glycolipid and sphingolipid are as cerebroside, ceramide and lecithin.

The example that is applicable to this amphiphilic surfactant comprises following amphoteric, anionic, the cationic and non-ionic surfactant of listing that contains C8-C30 alkyl and acyl group.

Amphoteric:

N-alkyl amino acid (as N-p dialkylaminobenzoic acid sodium);

N-lauroyl glutamate cholesterol ester (for example Eldew CL-301 Ajinomoto)

Anionic:

Acyl glutamate (as: N-lauroyl glutamate disodium);

Sarcosinate (as: sodium lauryl sarcosinate, Grace, Seppic);

Taurate (taurates) (as: lauryl sodium taurocholate, the basic sodium taurocholate of methyl Cortex cocois radicis (acyl));

Carboxylic acid and salt (as: potassium oleate, potassium laurate, 10-potassium undecylenate, 11-(to styryl)-hendecanoic acid potassium);

The carboxylate of ethoxylation (as methyl alkyl ethoxylation carboxylic acid sodium)

The ether carboxylic acid;

Phosphate ester and salt (as: lecithin, DEA-oleth-10 phosphate);

Acyl isethinate (as: 2-lauroyl oxygen ethyl sulfonic acid sodium);

Alkylsulfonate (as: the X-sodium alkyl sulfonate (x/l) of branching;

Sulfosuccinate ester salt, as

Sulfosuccinic dibutyl phthalate sodium,

2-Sulfosuccinic acid two-2-pentyl ester sodium,

2-Sulfosuccinic acid two-2-ethyl butyl ester sodium,

2-Sulfosuccinic acid dihexyl sodium,

2-Sulfosuccinic acid two-2-Octyl Nitrite sodium (AOT),

2-Sulfosuccinic acid two-2-ethyl dodecyl ester sodium,

2-Sulfosuccinic acid two-2-ethyl stearyl sodium,

Sodium docusate,

2-Sulfosuccinic acid laureth ester disodium (Mackanate EI, McIntyre GroupLtd.)

Sulfuric ester (as: sulphuric acid (2-ethyl heptan-6-alkene) ester sodium, sulphuric acid (11-heneicosane) ester sodium, sulphuric acid (9-heptadecane) ester sodium),

Alkyl sulfate/salt (as: MEA alkyl sulfate/salt, for example MEA-lauryl sulfate ester/salt).

Cationic:

Alkyl imidazoline (for example: alkyl hydroxyethyl imidazoline, octadecyl hydroxyethyl imidazole quinoline (supplier has Akzo, Finetex and Hoechst));

Ethoxylated amine (as: PEG-n alkylamine, PEG-n alkyl amino propylamine, Poloxamine, PEG-cocoa polyamines, PEG-15 tallow amine);

Alkylamine (as: dimethyl alkylamine, dihydroxy ethyl alkylamine dioleate).

Quaternary compound:

Alkyl benzyl dimethyl ammonium salt (as: stearalkonium chloride);

Alkyl betaine (as: dodecyl dimethyl ammino (ammonio) acetas, oil-based betaine);

Heterocycle ammonium salt (as: alkyl ethyl morpholine ethyl-sulfate);

Tetraalkylammonium salt (as: dimethyl dioctadecyl ammonium chloride (Witco));

The chloride (the Schercoquat 21AP of ScherChemicals company) of two-(isooctadecane acylamino-propyl group hydroxypropyl) diammonium

1.8-two (decyl dimethyl amminos)-3,6-dioxo octane xylene sulfonate.

Non-ionic surface active agent:

The ethoxylated glycerol ester;

Monoglyceride (as: glycerin mono-fatty acid ester, glycerol list linoleate, glyceryl monolaurate, 1-dodecanoyl-glyceryl monolaurate, 1,13-docosene acyl-glycerol list eruciate;

The double glyceride fatty acid (as: diglycerol list isooctadecane acid esters Cosmol 41, fractionated, Nisshin Oil Mills Ltd.);

Polyglycerol esters (as: Triglyceryl monooleate (Grindsted TS-T122), two glycerin mono-fatty acid esters (Grindsted TST-T101));

Polyhydroxy alkyl ester and ether (as: sucrose cocoa acid esters, and cetearyl (cetostearyl) glucoside (Montanol, Seppic), β-octyl group-glucofuranose glycosides ester, alkyl-glucoside, as C10-C16 (Henkel));

Di-phosphate ester (as: di(2-ethylhexyl)phosphate oil base ester sodium);

Alkyl amido CAB (as: cocoamidopropyl);

Amide (as: N-(dodecanoyl aminoethyl)-2-Pyrrolidone);

Amide oxide (as: 1,1-dihydro perfluoro capryl dimethyl amine oxide, dodecyl dimethyl amine oxide, 2-hydroxyl-dodecyl dimethyl amine oxide, 2-hydroxyl-dodecyl-two (2-ethoxy) amine oxide, 2-hydroxyl-4-oxa--hexadecyldimethyl benzyl ammonium amine oxide);

Ethoxylation amide (as: PEG-n amide);

Ammino phosphate ester (as: two caprinoyl lecithins);

Amine (as: octylame);

The ammino amide, as:

N-trimethyl ammino caprinoyl aminate,

N-trimethyl ammino 12 phosphinylidyne aminates,

The ammino carboxylate, as

Dodecyl dimethyl ammino acetas,

The two dodecyl methyl ammino alkyl caproates of 6-,

Phosphonate ester and phosphate ester and amide, as:

Methyl-N-methyl-dodecyl-phosphonic acid amide thing,

Dodecyl phosphonic acids dimethyl esters,

Methylphosphonic acid dodecyl methyl ester,

N, N-dimethyl dodecyl phosphonic acids diamides

Ethoxylated alcohol,

Polyoxyethylene (C8), as:

Five Polyethylene Glycol P-n-octyl phenyl ethers,

Six Polyethylene Glycol P-n-octyl phenyl ethers,

Nine Polyethylene Glycol P-n-octyl phenyl ethers

Polyoxyethylene (C10), as

Five Polyethylene Glycol P-n-decyl phenyl ethers, decyl glycerin ether, 4-oxa--tetradecane-1,2-glycol, nine Polyethylene Glycol P-n-decyl phenyl ethers.

Polyoxyethylene (C11), as:

Four Polyethylene Glycol undecyl ethers

Polyoxyethylene (C12), as:

3,6,9,13-four oxa-pentacosanes-1, the 11-glycol,

3,6,9-trioxa docosane-1, the 8-glycol,

3,6,9,12,16-five oxa-octacosanes-1, the 14-glycol,

3,6,9,12,15-five oxa-nonacosanes-1, the 17-glycol,

3,7-two oxa-nonadecanes-1, the 5-glycol,

3,6,12,15,19-six oxa-hentriacontanes-1, the 16-glycol,

Five Polyethylene Glycol lauryl ethers,

Nine Polyethylene Glycol dodecylphenyl ethers.

Polyoxyethylene (C14), as:

3,6,9,12,16-five oxa-octacosanes-1, the 14-glycol,

3,6,9,12,15,19-six oxa-melissanes-1,17-glycol.

The sulfone diimine, as:

Decyl methyl sulfone diimine.

Sulfoxide; As:

3-oxygen in last of the ten Heavenly stems base-2-hydroxyl-propyl group methyl sulfoxide,

4-oxygen in last of the ten Heavenly stems base-3-hydroxyl-butyl methyl sulfoxide.

Sulfoximines, as:

N-methyl dodecyl methyl sulfoximine.

Here preferred organic amphiphilic surfactant is the ion-type amphiphilic surfactant, it has the polyol ester of being selected from, the hydrophilic segment of poly-alkoxylation polyol ester and composition thereof, polyhydric alcohol is preferably selected from sugar, the C2-C6 aklylene glycol, glycerol, polyglycereol, sorbitol, anhydro sorbitol, Polyethylene Glycol and polypropylene glycol, and wherein every mole of polyol ester contains about 2 to about 20 in the poly-alkoxylation polyol ester, preferred about 2 to about 4 moles alkylene oxide (especially ethylene oxide), this surfactant also has oleophilic moiety, it is selected from saturated or unsaturated long branched chain or linear oleophylic chain, it has about 12 to about 30 carbon atoms, as oil base, the lanoline base, myristyl, cetyl, iso stearyl, lauryl, the cocoa base, stearyl or alkyl phenyl chain.

Highly preferred employed in the present invention organic amphiphilic surfactant is selected from polyol ester and ether.Especially preferred amphiphilic surfactant is sugar ester, poly-alkoxylation sugar ester.

Employed sugar ester can be categorized as the alkyl and the alkyl polyoxy alkylidene ester of ring-type polyhydroxy saccharide among the present invention, and wherein one or more hydroxyls of sugar moieties are replaced by acyl group or polyoxy alkylidene.The alkyl sugar ester can prepare by the mode of knowing, promptly add hot acid or carboxylic acid halides and sugar prepare by simple esterification.

The used steamed bun stuffed with sugar of preparation sugar ester is drawn together monosaccharide, disaccharide and the oligosaccharide of knowing in this area, for example glucose of dextrorotation and levorotatory form, fructose, mannose, galactose, arabinose and xylose.Typical disaccharide comprises maltose, cellobiose, lactose and trehalose.Typical trisaccharide comprises Raffinose and gentianose.Here the disaccharide that preferably uses is sucrose.

One or more in eight hydroxyls of sucrose can be esterified to produce employed sucrose ester here.When sucrose when mol ratio combined with 1: 1 with esterifying agent, form sucrose monoester; When the ratio of esterifying agent and sucrose is 2: 1 or when bigger, form diester, three esters etc., until the highest octaester.

Here preferred sugar ester is that those pass through esterifying agent: sugared mol ratio is the sugar ester prepared in reaction of 1: 1 and 3: 1 o'clock, i.e. monoacyl and two or three acyl group sugar esters.Especially preferred is list, two and three acyl group sugar esters and composition thereof, and wherein acyl substituent contains about 8 to about 24 carbon atoms, and preferred about 8 to about 20 carbon atoms and 0,1 or 2 unsaturated part.In monoacyl and diacyl sugar ester, especially preferred disaccharide sugar, sucrose ester separately especially, wherein acyl group contains about 8 to about 20 carbon atoms.Here preferred sugar ester is sucrose cocoa acid esters, sucrose monooctanoate, sucrose monocaprate, sucrose monolaurate, sucrose list myristate, sucrose palmitic acid ester, Sucrose monostearic acid ester, sucrose monooleate acid esters, sucrose list linoleate, sucrose dioleate, sucrose dipalmitate, sucrose distearate, sucrose dilaurate and sucrose dilinoleic acid ester, and composition thereof.The cocoa acid esters of having found sucrose is effective especially in the present composition.Monoacyl sugar ester and two, three and the mixture of the sugar ester of more acyl groups in, single and diacyl ester preferably account for sugar ester mixture total weight amount at least about 40%, more preferably from about 50% to about 95%.

Other sugar ester that is applicable to the present composition is an alkyl polyoxy alkylidene sugar ester, and one of them hydroxyl is by C ₈-C ₁₈Alkyl replaces, and the one or more hydroxyls on the glycan molecule are contained [(CH ₂) _x-O] _yThe ester or the ether substituent group of polyoxy alkylidene substituent group part replace, and wherein X is 2 to about 4,, be preferably 2 integer, Y is about 1 to about 50, preferred 8 to 30 integer.Here the polyoxy alkylidene substituent group in the especially preferred sugar ester is to contain the about 8 polyoxyethylene substituent groups to about 30 polyoxyethylene groups.Anhydro sorbitol is that this class material of sugar moieties can be purchased under commodity " Tweens ".The preparation of this class mixed ester is: at first take acyl group sugar with the alkyl carboxylic acid halides with 1: 1 mol ratio, subsequently with corresponding polyoxy alkylidene carboxylic acid halides or reactions of alkylene oxide to make required material.The simple polyoxy alkylidene ester of disaccharide, especially sucrose (wherein polyoxy alkylidene group contain be no more than about 20 oxyalkylene parts) is another kind of here useful sugar ester.The preferred sugar ester of this apoplexy due to endogenous wind is the sorbitol olein with 20 moles of ethylene oxide ethoxylations.The mixture of sugar ester and other polyol esters such as diol ester also can be used for this, for example Plam OilSucroglyceride (Luo Na-Rhone-Poulenc).

Terminology used here " lecithin " is meant the material into phospholipid.Can use natural or synthetic phospholipid.Phosphatidylcholine or lecithin are the glycerol with the cholinester esterification of phosphoric acid and two kinds of fatty acids, and fatty acid wherein normally has 16-20 carbon atom and is no more than the saturated or unsaturated fatty acid of 4 two bond distance's chains.Other phospholipid that can form stratiform or hexagon liquid crystal can replace lecithin to use or mix use with it.These phospholipid are the same with lecithin to be the glyceride that forms with two kinds of fatty acids, but choline is by ethanolamine (cephalin) or serine (alanine; Phosphatidylserine) or inositol (phosphatidylinositols).Although the present invention illustrates with lecithin, think that other phospholipid of this class also can use.

Can use many kinds of lecithin.American Lecithin Company supply Nattermann Phospholipid, Phospholipan 80 and Phosal 75.Other the lecithin that can use separately or be used in combination with these is: from Actifla Series, Centrocap Series, Central Ca, Centrol Series, Centrolene, Centrolex, Centromix, Centrophase and the CentrolphilSeries of Central Soya company; Alcolec and Alcolec 439-C from American Lecithin company; From the Canaspersa of Canada Packers company, from the Lexin K and the Natipide of American Lecithin company; With L-Clearate, Clearate LV and Clearate WD from W.A.Cleary Co. company.The lecithin of supply is dissolved in ethanol, fatty acid, triglyceride and other solvent.Their mixture of lecithin normally during supply, and be 15% to 50% solution.

Natural can use with synthetic lecithin.Natural lecithin comes from oily seed, as Semen Helianthi, Semen sojae atricolor, Semen Flos Carthami and Semen Gossypii.Lecithin decomposes from oil in subtractive process.

Found that organic amphiphilic surfactant is especially valuable to the stability and the skin feel that improve the present composition.

In the compositions addition of amphiphilic surfactant be preferably composition weight about 0.1% to about 20%, preferred about 0.1% to about 10%, more preferably from about 0.1% to about 8%.

Here highly preferred a kind of fatty acid ester blends, it is based on the mixture of anhydro sorbitol or Span and sucrose fatty acid ester, the preferred C8-C24 of fatty acid in every kind of situation, more preferably C10-C20.From the angle of humidification, preferred fatty acid ester emulsifier is blend, the especially sorbitan monostearate of anhydro sorbitol or sorbitol C16-C20 fatty acid ester and sucrose C10-C16 fatty acid ester and the blend of sucrose cocoa acid esters.This can be that the commodity that are purchased from ICI are the product of Arlatone 2121.

Here compositions comprises oil or oil mixture.From physically, usually compositions is an emulsion form, and one or more oil phases are scattered in and contain in the water continuous phase, and each oil phase comprises single kind of oil ingredient, or with the mixture of the oil ingredient of homogeneous form perhaps mutually, but contain different material or different mixture of substances between the different oil phase.The total content of oil phase component is preferably about 0.1% to about 60% in the present composition, and preferred about 1% to about 30%, and more preferably from about 1% to about 10% weight.

The present composition preferably comprise contain polysiloxanes first as all or part of of above-mentioned oil phase, it includes crosslinked poly-organopolysiloxane and silicone oil, wherein comprise and account for composition weight 0.1% to about 20%, preferred 0.5% to about 10%, more preferably from about 0.5% to about 5% the crosslinked polysiloxane and the mixture of silicone oil.

Contain first of polysiloxanes and comprise mutually and account for its weight about 10% to about 40%, more preferably from about 20% to about 30% crosslinked poly-organopolysiloxane and about 60% is to about 90%, preferred about 70% to about 80% silicone oil.

Crosslinked poly-organopolysiloxane comprises with the crosslinked poly-organopolysiloxane of cross-linking agent.The cross-linking agent here comprises any cross-linking agent that is used to prepare crosslinked polysiloxane.Here the cross-linking agent of Shi Yonging comprises those that following formula is represented:

Wherein R1 is methyl, ethyl, propyl group or phenyl, R2 be H or-(CH ₂) nCH=CH ₂, wherein n is about 1 to about 50 number, and z is about 1 to about 1000 number, and preferred about 1 to about 100, and R is the alkyl of C1-C50.

Preferred cross-linking agents has general formula:

Wherein R1, R2 and z as above define.

In especially preferred embodiment, cross-linking agent has following general formula:

Wherein z is about 1 to about 1000 number, preferred about 1 to about 100.

Crosslinked polysiloxane preferably comprise account for its weight about 10% to about 50%, 20% to about 30% cross-linking agent more preferably from about.

Here can adopt any poly-organopolysiloxane that is applicable to skin care compositions.Here Shi Yi poly-organopolysiloxane comprises those of following general formula:

Wherein R1 is methyl, ethyl, propyl group or phenyl, R2 be H or-(CH ₂) nCH=CH ₂Wherein n is about 1 to about 50 number, R3 and R4 independently are selected from methyl, ethyl, propyl group and phenyl, and R is a terminal groups, as the C1-C50 alkyl of nonessential hydroxyl replacement, preferred C1-C5 alkyl, more preferably C1-C2 alkyl, p is about 1 to about 2000 integer, preferred about 1 to about 500, q is about 1 to about 1000 integer, preferred about 1 to about 500.

In preferred embodiments, poly-organopolysiloxane is selected from the polymer of following formula:

Wherein R1, R2, R3, R4, p and q as above define.

As what define here, the number of Si-O connection unit in p and the q reflection polymer chain, R1 and R2 and R3 and R4 can change to another monomeric unit from a monomeric unit.For example, the suitable poly-organopolysiloxane that adopts here comprises methyl ethylene dimethicone, methyl ethylene diphenyl dimethicone and methyl ethylene phenyl methyl diphenyl dimethicone.

Crosslinked in order between poly-organopolysiloxane and cross-linking agent, to produce, (Si-H) base must with-Si-(CH ₂) nCH=CH ₂Group is crosslinked, makes for any specific crosslinked, and the R2 group is necessary different in poly-organopolysiloxane and cross-linking agent.For example, for any specific crosslinked, when R2 in poly-organopolysiloxane is-(CH ₂) nCH=CH ₂The time, R2 must be H in cross-linking agent, vice versa.But, concerning every kind of poly-organopolysiloxane and cross-linking agent, can have the mixture of R2.

In preferred embodiments, poly-organopolysiloxane is selected from the alkylaryl polysiloxanes with following general formula:

Wherein R2 is selected from-CH=CH ₂Or H, preferred-CH=CH ₂, and wherein l is about 1 to about 1000, and preferred about 1 to about 500 integer, m are 0 to about 1000, and preferred about 0 to about 500 integer, n are about 1 to about 1000, preferred about 1 to about 100 integer.

Wherein l, m and n are as mentioned above.In preferred embodiments, m is about 1 to about 1000, preferred about 200 to about 800.

Contain first of polysiloxanes and also comprise silicone oil mutually.Any straight chain, side chain and the cyclic polysiloxanes that are applicable to skin care compositions are applicable to this.Silicone oil can be volatility or nonvolatile.The silicone oil that is suitable for that is used for this comprises weight average molecular weight about 100,000 or lower silicone oil, and preferable weight-average molecular weight is 50,000 or lower.It is about 100 to about 50,000 that preferred silicone oil is selected from weight average molecular weight, preferred about 200 to about 40,000 silicone oil.In preferred embodiments, silicone oil is selected from dimethicone, decamethylcyclopentaandoxane, octamethylcy-clotetrasiloxane and phenyl methyl polysiloxanes and composition thereof, most preferably phenyl methyl polysiloxanes.

The suitable substance that is applicable to first phase that contains polysiloxanes can be the product of the commodity KSG by name that provides of Shinetsu chemistry company limited, for example KSG-15, KSG-16, KSG-17, KSG-18.These materials contain the crosslinked poly-organopolysiloxane and the combination of silicone oil.Especially be preferred for this, particularly the material that combines with organic amphiphilic emulsifying agent is KSG-18.The INCI title of KSG-15, KSG-16, KSG-17, KSG-18 regulation is respectively cross linked polymer, dimethicone dimethicone/vinyl dimethicone crosspolymers, SILIBIONE OIL 70047 V20 DC-21330 DC21330 dimethicone/vinyl dimethicone crosspolymers and the phenyl front three polysiloxanes dimethicone/phenyl vinyl dimethicone cross linked polymer of SILIBIONE OIL 70047 V20 DC-21330 DC21330 dimethicone/vinyl-dimethyl polysiloxanes.

Here preferred compositions also comprises second phase that contains noncrosslinking polysiloxanes.In preferred embodiments, the content that contains second phase of polysiloxanes be compositions weight about 0.1% to about 20%, especially about 0.1% to about 10%.

The suitable polysiloxane fluid that is used for this second phase that contains polysiloxanes comprises non-volatile poly-alkyl and poly-aryl silicone gum and fluidic water-insoluble polysiloxanes, volatile ring-type and linear poly-alkylsiloxane, poly-oxyalkylsiloxane, amino and quaternary ammonium modified polyorganosiloxane and composition thereof.

In preferred embodiments, contain the polysiloxane mixture that second of polysiloxanes comprises silicone gum mutually or contains it.It is about 200,000 to refer to that at this term " silicone gum " the quality mean molecule quantity surpasses, preferred about 200,000 to about 400,000 high-molecular weight fluid based on polysiloxanes.Silicone oil generally has and is lower than about 200,000 molecular weight.Usually, they are under 25 ℃, and it is about 1,000 that viscosity surpasses, 000mm ²s ^-1Silicone gum comprises the US-A-4 that licensed to comprising of Petrarch and other people such as Spitzer etc. on May 1st, 1979,152,416, and Noll, " chemistry and technology of siloxanes " of Walter, New York, publishing house of institute, 1968 described dimethicones.General Electric's silicone rubber products catalog SE30 in addition, SE33, SE54 has also described silicone gum among the SE76.

The silicone gum that is used for this comprises any silicone gum that is applicable to skin care compositions.The molecular weight that is used for this suitable silicone gum is about 200,000 to about 4,000,000, is selected from dimethicone alcohol, fluoro polysiloxanes and dimethicone and composition thereof.

The siloxanes based on dimethicone alcohol that is suitable for this has following chemical constitution (II):

HO(CH ₃) ₂SiO[(CH ₃) ₂SiO] _n(CH ₃) ₂SiOH

In the formula, it is about 40,000 that n is about 2000-, preferably about 3000-about 30,000.

Can be about 200,000 to about 300,000, preferred about 240,000 to about 260,000 at the molecular weight of the fluoro polysiloxanes of this useful illustrative, most preferably from about 250,000.

The example of concrete silicone gum comprises polydimethylsiloxane, (polydimethylsiloxane) (ethylene methacrylic radical siloxane) copolymer, poly-(dimethyl siloxane) (diphenyl) (ethylene methacrylic radical siloxane) copolymer and composition thereof.

The silicone gum that is used for this can add the part of compositions as polysiloxane mixture, and it preferably accounts for about 5% to about 40%, especially about 10% to about 20% of polysiloxane mixture weight weight.Polysiloxanes or polysiloxane mixture preferably account for composition weight about 0.1% to about 20%, more preferably from about 0.1% to about 15%, especially about 0.1% to about 10%.

Being used for the suitable polysiloxane mixture based on silicone gum that the present composition contains second phase of polysiloxanes comprises basically by the following mixture of forming:

(i) from dimethicone alcohol (dimethiconol), the molecular weight of selecting in fluoro polysiloxanes and dimethicone and composition thereof is about 200, about 4,000,000 the polysiloxanes of 000-,

The (ii) about 100mm of the about 0.65-of viscosity ².s ^-1The carrier based on polysiloxanes.

At this, (i), ratio (ii) is about 10: 90 to about 20: 80, and the final viscosity of wherein being mentioned based on the silicone components of silicone gum is about 500 to about 10,000mm ².s ^-1

The carrier based on polysiloxanes that is suitable for this comprises certain polysiloxane fluid.Siloxanes fluids may be poly-alkylsiloxane, poly-aryl siloxanes, polyoxyethylene alkyl aryl radical siloxane or polyether siloxane copolymer.In certain embodiments, also use and preferred these fluidic mixture.

The poly-alkylsiloxane fluid that can be used comprises, for example, is about 0.65-600,000mm 25 ℃ of following viscosity ².s ^-1, preferred about 0.65 to about 10,000mm ².s ^-1Polydimethylsiloxane.These polysiloxanes for example can obtain from Dow Corning 200 series of the Viscasil (RTM) of General Electric Co. Limited series and Dow Corning Corporation.Substantially the nonvolatile polyoxyethylene alkyl aryl radical siloxane fluid that can be used comprises that as under 25 ℃, viscosity is about 0.65-30,000mm ².s ^-1PSI.These polysiloxanes can obtain from 556 cosmetics-stage fluids as the SF1075 aminomethyl phenyl fluid of General Electric Co. Limited or Dow Corning Corporation.Some has and contains about 3 to about 7 (CH at this ₃) ₂The volatile cyclic polydimethylsiloxane of the ring structure of SiO part also is suitable for.

According to the regulation of the test method CTM004 of Dow Corning Corporation on the 29th July in 1970, measure viscosity by a kind of glass capillary tube viscometer.The viscosity preferably about 500 of polysiloxane mixture of forming the second fluid phase is to about 100,000mm ².s ^-1, more preferably from about 1000 to about 10,000mm ².s ^-1

In this especially preferred component based on silicone gum is that a kind of molecular weight is about 200, and about 4,000,000 dimethicone alcohol gum stock of 000-and viscosity are about 0.65-100mm ².s ^-1Silicone carrier.The Dow Corning Q2-1403 (85%5mm that an example of this polysiloxanes component is a Dow Corning Corporation ².s ^-1Dimethicone fluid/15% dimethicone alcohol) and Dow Corning Q2-1401.

Be applicable to that at this another kind of polysiloxanes component of second phase that contains polysiloxanes comprises the poly-diorganosiloxane-polyoxyalkylene copolymers that contains at least one poly-diorganosiloxane segment and at least one polyoxyalkylene segment.The poly-diorganosiloxane segment of being mentioned is basically by R _bSiO _(4-b)/2Siloxane unit is formed, wherein the b value is about 3 (comprising) of about 0-, for all siloxane units in the copolymer, each silicon atom contains average about 2 R groups, R represents from methyl, ethyl, vinyl, the group that the polyoxyalkylene segment that phenyl and a kind of combination are mentioned is selected in the poly-segmental bilvalent radical of diorganosiloxane is a methyl at least about 95% in all R bases; The mean molecule quantity of the polyoxyalkylene segment of being mentioned is at least about 1000, form by the polyoxyethylene units of the polypropylene oxide unit of the about 50mol% of about 0-and the about 100mol% of about 50-, the poly-diorganosiloxane segment that the polyoxyalkylene segment of being mentioned has at least a terminal combination to be mentioned, the end that any one of the polyoxyalkylene segment of being mentioned is not joined on the poly-diorganosiloxane segment of being mentioned is all saturated by an end group; In the copolymer of being mentioned, the weight ratio of poly-diorganosiloxane segment and polyoxyalkylene segment is about 2 to about 8.These polymer can be referring to US-A-4, and 268,499.

At this poly-diorganosiloxane-polyoxyalkylene copolymers that preferably uses general formula is arranged:

X in the formula, it is about 8 that the choosing of y makes the weight ratio of poly-diorganosiloxane segment and polyoxyalkylene segment be about 2-, mol ratio a: (a+b) about 0.5 to about 1, and R is a terminated radical, especially from hydrogen; Hydroxyl; Alkyl such as methyl, ethyl, propyl group, butyl, benzyl; Aryl such as phenyl; Alkoxyl such as methoxyl group, ethyoxyl, propoxyl group, butoxy; Benzyloxy; Aryloxy group such as phenoxy group; Alkene oxygen base such as ethyleneoxy and allyloxy; Acyloxy such as acetoxyl group, acryloxy, propionyloxy is with amino as to choosing in the dimethylamino.

Copolymer medium chain hop count and segment mean molecule quantity should make the weight ratio preferably about 2.5 to about 4.0 of poly-diorganosiloxane segment and polyoxyalkylene segment.

Commercially available suitable copolymer is the Wacker-Chemie company limited, CompanyAddress: Geschaftsbereich S, the trade name Belsil (RTM) and the Th.Goldschmidt company limited in Postfach D-8000 Munich 22, CompanyAddress: TegoHouse, Victoria Road, Ruislip, Middlesex, the product of the trade name Abi of HA40YL (RTM).At this preferred especially Belsil (RTM) 6031 and Abil (RTM) B88183.Here especially preferred copolymer comprises the Dow Corning DC 3225C with CTFA called after dimethicone/dimethicone polyol.

Non-essential composition

In preferred embodiments, the 3rd oil phase account for composition weight about 0.1% to about 15%, more preferably from about 1% to about 10%.The 3rd oil phase can be independent phase or with first and second mutually in one mutually or biphase formation one phase.Preferred the 3rd oil phase is independent phase.

The 3rd oil phase preferably includes the organic oil of non-silicone, as from mineral, and vegetable, the oil of animal, fat and wax, fatty acid ester, aliphatic alcohol, the natural or artificial oil of selecting in fatty acid and their mixture that is used to improve moisturizing cosmetics character.The preferred essentially no polysiloxanes of first oil phase component promptly is no more than approximately 10% by weight based on the material content of polysiloxanes, preferably be no more than about 5%.Be appreciated that oil phase for example can contain, at most about 25%, preferred at most only 10% oil phase solubility emulsifying agent compositions.Consider that from decision oil phase amount and required HLB angle these components are not considered to oil phase component.In preferred embodiments, it is about 12 that the required total HLB of oil phase is about 8-, is about 9-about 11 especially.Required HLB depend on the required monomer HLB value of each component in the oil phase and its percentage by weight in oil phase product add and (referring to the ICI Literature of relevant HLB system, ICI reference paper ref51/0010/303/15m., the first seal in 1976 is in May, 1984 and 1992 revision).

First oil phase component that is applicable to this for example comprises, the C that optional hydroxyl replaces ₈-C ₅₀Unsaturated fatty acid and ester thereof, C ₈-C ₃₀The C of satisfied fatty acid ₁-C ₂₄Ester such as isopropyl myristate, isopropyl palmitate, cetyl palmitate and Wickenol 142 (Wickenol 142), Cera Flava, saturated and unsaturated fatty alcohol such as the pure and mild spermol of docosane, hydrocarbon such as mineral oil, vaseline and squalane, fat dehydration Pyrusussuriensis sugar ester is (referring to the US-A-3988255 that authorized on October 26th, 1976, Seiden,), lanoline and lanolin derivative, triglyceride of animal and vegetable such as almond oil, Oleum Arachidis hypogaeae semen, wheat germ oil, Semen Lini oil, simmondsia belongs to oil, japanese plum seed oil, Oleum Juglandis, the Petiolus Trachycarpi fruit oil, pistachio nut oil, Oleum sesami, Oleum Brassicae campestris, cade oil, Semen Maydis oil, peach kernel oil, poppy seed oil, Oleum Pini, Oleum Ricini, Oleum Glycines, American Avocado Tree oil, safflower oil, Oleum Cocois, hazelnut oil, olive oil, Oleum Vitis viniferae, Adeps Bovis seu Bubali resin, the C of sal fat and Oleum Helianthi and dimerization and trimer acid ₁-C ₂₄Ester, as the dimeric dibasic acid diisopropyl ester, malic acid two iso stearyl esters, dimeric dibasic acid two different stearyl esters, trimer acid three different stearyl esters.In the said components, it is highly preferred that mineral oil, vaseline, unsaturated fatty acid and ester thereof and their mixture.

Comprise about by weight 0.1% to about 10% unsaturated fatty acid or ester in these preferred a plurality of embodiments.At this unsaturated fatty acid that preferably uses and ester is the C that optional hydroxyl replaces ₈-C ₅₀The ester of unsaturated fatty acid and ester, particularly castor oil acid.In this unsaturated fatty acid or ester component with becoming liquid crystal emulsifier to use together and rubbing that to wipe the infiltration characteristic be important to the dermal sensation that improves compositions.This respect is the ricinoleic acid cetyl most preferably.

Here the compositions preferred ingredients is the polyol ester skin conditioning agent except organic amphiphilic surfactant.

Compositions of the present invention preferably comprises about 0.01% to about 20%, and more preferably from about 0.1% to about 15%, especially preferred about 1% to about 10% heavy polyol ester.Level of polyol ester be preferably oil content weight in the compositions about 1% to about 30%, more preferably from about 5% to about 20%.

Here the preferred polyol ester that uses is the liquid or liquable polyol carboxylate of non-occlusive.This polyol ester is derived with one or more hydroxy-acid groups or part by a kind of polyhydric alcohol group or part.In other words, these esters comprise a part and an one or more part of being come by carboxylic acid derivatives of being come by polyol derivative.These carboxylates also can come from carboxylic acid derivatives.These carboxylates also can be described to liquid fat acid polyol resin, because for the expert of those technical fields, term carboxylic acid and fatty acid normally can exchange use.

The preferred liquid polyol polyester that uses contains certain polyhydric alcohol among the present invention, particularly by the sugar of at least four fatty acid group esterifications or sugar alcohol.Correspondingly, but the polyhydric alcohol raw material must have the hydroxyl of at least four esterifications.The example of preferred polyhydric alcohols is a sugar, comprises monosaccharide and disaccharidase and sugar alcohol.The example that contains the monosaccharide of four hydroxyls is xylose and arabinose, and the sugar alcohol that five hydroxyls are arranged of being derived and by xylose, i.e. xylitol.The monosaccharide erythrose is unsuitable for the present invention and uses, because it only contains 3 hydroxyls, but the sugar alcohol that contains four hydroxyls of deriving and from erythrose, promptly erithritol can use.The suitable monosaccharide that contains five hydroxyls is galactose, fructose and sorbose.The sugar alcohol that contains 6 hydroxyls from sucrose and glucose and sorbose hydrolyzate are derived and as sorbitol, also is well suited for.The example of available disaccharidase polyhydric alcohol comprises maltose, lactose and sucrose, and all these is the disaccharidase polyhydric alcohol that contains eight hydroxyls.

The polyhydric alcohol that is used for preparing the polyester that uses in the present invention preferably is selected from erithritol, xylitol, sorbitol, dextrose plus saccharose.Particularly preferably be sucrose.

Polyhydric alcohol raw material with at least four hydroxyls is to have at least four hydroxyls to be contained about 8 ester fat acid esterizations to about 22 carbon atoms.That the example of this class fatty acid comprises is sad, decanol, lauric acid, myristic acid, myristoleic acid, Palmic acid, palmitoleic acid, stearic acid, oleic acid, castor oil acid, linoleic acid, linolenic acid, eleostearic acid, arachidic acid, arachidonic acid, behenic acid and erucic acid.These fatty acids can be derived by natural or synthetic fatty acid, and they are saturable or undersaturated, comprise position isomer and geometric isomer.But for the preferred herein liquid polyester that uses is provided, the about at least 50% heavy fatty acid that adds in the polyester molecule should be undersaturated, and oleic acid, linoleic acid and composition thereof are particularly preferred.

The fatty polyol polyester that can use in the present invention must comprise at least four fatty acid ester group.Though all hydroxyls of polyhydric alcohol needn't be by fatty acid esterification, preferably polyester comprises and is no more than two nonesterified hydroxyls.Most preferably, all hydroxyls of polyhydric alcohol are all by fatty acid esterification, and promptly polyol moiety is esterified substantially fully.The fatty acid of esterification polyol molecule can be identical or blended, but as above-mentioned, have a considerable amount of unsaturated acids ester groups to exist to guarantee that this polyester is a liquid form.

For above-mentioned viewpoint is described, sucrose fat three esters are not suitable for this, because it does not contain four required fatty acid ester group.Sucrose-fatty four esters are fit to, but are not preferred, because it has the hydroxyl more than two esterification.Sucrose-fatty six esters are preferred, because it has no more than two nonesterified hydroxyl.All hydroxyls are comprised the substituted fatty acid octaester of liquid sucrose in the highly preferred molecule by fatty acid-esterified chemical compound.

Below be to be applicable to the non-limitative example that contains the concrete fatty polyol polyester of at least four fatty acid ester group of the present invention: four oleic acid glucose esters, the glucose tetra-ester of soy(a)-bean oil fatty acid (unsaturation), mannose four esters of mixed soy(a)-bean oil fatty acid, oleic galactose four esters, linoleic arabinose four esters, four linoleic acid xylose esters, five oleic acid gala sugar esters, four oleic acid sorbitol esters, sorbitol six esters of undersaturated soy(a)-bean oil fatty acid, the five oleic acid esters of xylitol, four oleic acid sucrose ester, five oleic acid sucrose ester, six oleic acid sucrose ester, seven oleic acid sucrose ester, eight oleic acid sucrose ester, and composition thereof.

As noted above, highly preferred polyol fatty acid ester be those wherein fatty acid contain the ester of about 14 to 18 carbon atoms.

Here the complete fusing point of preferred liquid polyol polyester is lower than about 30 ℃, preferably is lower than about 27.5 ℃, and more preferably is lower than about 25 ℃.Here Bao Dao complete fusing point is to be recorded by differential scanning calorimetry (DSC).

Be fit to that the fatty polyol polyester can be by prepared in various methods as used herein, these methods are thoroughly cookedly to know to those experts in this technical field.These methods comprise: the transesterification of carrying out with polyhydric alcohol and fatty acid methyl ester, ethyl ester or the glyceride of various catalysts; The acylation that polyhydric alcohol and fatty acid acyl chlorides carry out; The acylation that polyhydric alcohol and fatty acid anhydride carry out; The acylation that polyhydric alcohol and fatty acid carry out itself.See and licensed to the U.S.P.No.2 of Jandacek, 831,854 on January 25th, 1977; With the U.S.P.No.4 that licensed to Jandacek on January 25th, 1977,005,196.

The highly preferred composition of said composition is a urea, and its content is preferably about 0.1% to about 20% by the weight of compositions, and more preferably from about 0.5% to about 10%, especially about 1%-about 5%.

In preferred embodiments, oil phase and organic amphiphilic substance mix in advance under the temperature of (but preferably being lower than about 60 ℃) more than the Kraft of the organic amphiphilic substance point and form liquid crystal/oil-in-water disperse system in water before adding urea.Find that at this urea uses providing excellent skin to heat and softening effective especially together with amphiphilic emulsifier surface activating agent and polyol fatty acid polyesters in oil-in-water skin protection emulsifier combination.And, find that shockingly urea becomes more stable for hydrolytic degradation.Therefore can increase the pH value of compositions.

Can add multiple nonessential component such as non-occlusive humidizer, wetting agent, gellant, nertralizer, spice, pigment and surfactant in this skin care compositions.

This compositions contains wetting agent.Suitable wetting agent comprises sorbitol, propylene glycol, butanediol, hexanediol, ethyoxyl glucosan derivative, hexanetriol, glycerol, glycine, hyaluronic acid, arginine, Ajidew (NaPCA), water-soluble poly glyceryl methacrylate lubricant and pantothenylol.Preferred humectants is a glycerol.From chemically analyzing, glycerol is 1,2, and the 3-glycerol is a kind of commodity.The main source of raw material is in soap is produced.From angle glycerol the present composition of auxiliary humidification is particularly preferred.At this butanediol in addition that preferably uses.From promoting the angle of humidification, the especially combination of preferably glycerine and urea.

In the present composition, humectant content is pressed composition weight meter preferably about 0.1% to about 20%, and more preferably from about 1%-is about 15%, especially preferably about 5%-about 15%.

The polyisobutylene acid glyceride lubricant that is suitable in the compositions of the present invention can be by Guardian chemical company, CompanyAddress: 230 Marcus Blvd., Hauppage, the commodity of N.Y.11787. are called in the product of Lubrajel (RTM) and obtain.Usually, Lubrajels may be described to hydrate or clathrate compound, and it is generated by sodium glycerinate and methacrylic acid polymer reaction.After this hydrate or clathrate compound are stable with a spot of butanediol, then control the product hydration.(monoglyceride: polymer) sell with multiple rank by ratio and viscosity by different for Lubrajels.The Lubrajel that is suitable for comprises Lubrajel TW, Lubrajel CG, Lubrajel MS, Lubrajel WA, Lubrajel DV and so-called Lubrajel Oil.

At least the part of wetting agent (can reach at most about composition weight 5%) can add with the form that particulate lipophilic or hydrophobic carrier material forms mixture.Carrier material and wetting agent both can be added to aqueous phase, also can be added in the decentralized photo.

Copolymer is to reducing gloss and control oiliness and helping to provide effective humidification benefit particular importance.Crosslinked hydrophobic polymer preferred copolymer form crystal lattice, it has at least a kind of active ingredient to disperse equably and wraps in the copolymer lattice.In addition, hydrophobic polymer can adopt surface area (N ₂, BET) about 50-500, preferred 100-300m ².g ^-1The porous particle form and absorbed active component therein.

The amount of crosslinked hydrophobic polymer preferred by weight about 0.1% is to about 10%, and preferably joins outside aqueous phase.Active ingredient may be a skin-friendliness oil, skin-friendliness wetting agent, emollient, one or more in humidizer and the sunscreen or mixture.In one embodiment, polymeric material adopts powder type, this powder is a groups of grains syzygy, powder particle system forms a kind of lattice, this lattice comprises that average diameter is less than 1 micron unit grain, the grumeleuse that the fused unit grain agglomerate of the about 20-100 micron of average diameter and the melt granules of the about 200-1200 micron of average diameter are agglomerated into.

The dusty material of this embodiment is described to crosslinked " absorbing the back " hydrophobic polymer lattice more.Powder preferably wherein is surrounded by and is dispersed with solid, the active ingredient that liquid or gas form exist.Lattice is a particulate forms, forms free-pouring discontinuous solid particle after adding active material.Lattice may contain the active material of scheduled volume.The polymer that is suitable for has structural formula:

The ratio of x and y is 80: 20 in the formula, and R ' is-CH ₂CH ₂-, R " be-(CH ₂) ₁₁CH ₃

Hydrophobic polymer is highly cross-linked polymer, the copolymer of particularly highly cross-linked polyisobutylene acid esters.This material is that the Dow Corning Corporation of the U.S.'s close supporting root state Midland produces, and sells with trade mark POLYTRAP (RTM).It is the free-pouring white powder of a kind of ultralight, and this granule can absorb the character that a large amount of lipophile liquids and some water seeking liquids keep free flowing powder simultaneously.Mealy structure is made up of the lattice less than 1 micron unit grain, and granule is melt into the agglomerate of 20-100 micron, and this agglomerate loosely is agglomerated into diameter about 200 to about 1200 microns bulky grain or grumeleuse.Polymer powder can hold the fluid of four times of its weight, emulsion, dispersion liquid or molten solids.

Available rustless steel mixing channel of effect and little spoon that active material absorbs on the polymer powder are finished, and at this, active component are added in the powder, lentamente active material are mixed in the polymer powder with little spoon.The low viscous flow body can contain in the sealed container of polymer by fluid being added to one, stirs then up to reaching certain denseness to be absorbed.Also can use more complicated mixing apparatus such as strip-type or double cone blender.At this, the preferred active ingredient that uses is a glycerol.The weight ratio of preferred humectants and carrier about 1: 4 to about 3: 1.

Microsponges 5647 also is suitable for as highly cross-linked polyisobutylene acid copolymer.It typically is the circular granular of crosslinked hydrophobic polymer, the have an appointment aperture of the about 0.05 μ m of 0.01-of this granule, surface area is 200-300m ²/ g.Preferably add wetting agent by above-mentioned amount.

Compositions of the present invention also contains a kind of hydrophilic gellant, and content preferably about 0.01% is to about 10%, and more preferably from about 0.02% to about 2%, and especially preferred about 0.02% to about 0.5%.Its viscosity (1% aqueous solution, 20 ℃, Brookfield RVT) is preferably at least about 4000mPa.s, more preferably at least about 10, and 000mpa.s, especially preferably at least about 50,000mPa.s.

Suitable hydrophilic gelling agent is described as water solublity or the water miscible polymer of colloidal state usually, comprises cellulose ether (hydroxyethyl-cellulose for example, methylcellulose, hydroxypropyl emthylcellulose), polyvinylpyrrolidone, polyvinyl alcohol, guar gum, hydroxypropyl guar gum and xanthan gum.

Yet, be that the trade mark of being sold by Goodrich Corporation is acrylic acid/ethyl acrylate copolymer and the carboxy vinyl polymer of Carbopol resins in this preferred hydrophilic gelling agent.These resins are basically by forming with the crosslinked acrylate copolymer of the crosslinked colloidal state water-soluble poly alkylene polyethers of 0.75%-2.00% cross-linking agent (as polyene propyl group sucrose or polyene propyl group tetramethylolmethane).Example comprises Carbopol 934, and Carbopol 940, and Carbopol 950, Carbopol954, and Carbopol 980, and Carbopol 951, and Carbopol 981.Carbopol 934 is crosslinked acrylic acid water-soluble polymers of sucrose polyallyl ether that 5.8 allyl group are arranged approximately with average each sucrose molecule of about 1%.Most preferred polymer is Carbopol 951.Hydrophobic modified acrylic crosslinking polymer with amphipathic characteristic also is suitable at this, and its article number is Carbopol 1382, Carbopol 1342 and Pemulen TR-1 (CTFA name: acrylate/acrylic acid 10-30 alkyl ester cross-linked polymer).The compositions of polyolefin-based polyethers crosslinked acrylic acid polymer and hydrophobic modified crosslinked acrylic acid polymer also is suitable for and preferred the use at this.Gellant under room temperature and elevated temperature to excellent stable particular importance is provided.

The nertralizer that the neutralization that is applicable to this contains the acidic-group of hydrophilic gelling agent comprises sodium hydroxide, potassium hydroxide, aqua ammonia, monoethanolamine, diethanolamine and triethanolamine.

Compositions of the present invention is an emulsion form, and preferred product viscosity is at least about 4000mPa.s, preferred about 4,000-300,000mPa.s, more preferably from about 8,000-is about 200,000mPa.s, especially preferred about 10,000-about 100,000mPa.s more preferred about 10,000 to about 50, (25 ℃ of 000mPaS, pure, Brookfield RVT Spindle No.5).

The present composition also contains has an appointment 0.1% to about 10%, preferred about 1% to about 5% pantothenylol humidizer.The pantothenylol humidizer can be from D-panthenol ([R]-2,4-dihydroxy-N-(3-hydroxypropyl))-3, the 3-amide dimethyl butyrate), the DL-pantothenylol, calcium pantothenate, Lac regis apis, pantethine (panthetine), pantetheine (pantotheine), general benzyl ethyl ether (panthenyl ethyl ether), vitamin B ₁₅, pyridoxin is selected in pantoyl lactose and the vitamin B complex.Consider from skin protection and minimizing viscosity angle, most preferably D-panthenol.

The present composition generally contains about by weight 0.001% to about 0.5%, and preferred about 0.002% to about 0.05%, more preferably from about 0.005% to about 0.02% carboxymethyl chitosan.Chitin is a kind of polysaccharide of the shell that is present in shrimp and Eriocheir sinensis and the mucopolysaccharide of N-acetyl group-D-glycosamine that a kind of β of containing-(1,4) connects.The chitin raw material of purification prepares carboxymethyl chitosan by handling with chloracetic acid then with alkali.Its commercial form sale with dilution (about by weight 0.1%-0.5%) aqueous solution is by the A ﹠amp of the Fordingbridge of Hampshire, Britain; E Connock company limited provides, and commodity are called Chitin Liquid.

Other nonessential raw materials comprise keratolytic such as salicylic acid; Protein and polypeptide and derivant thereof; But water solublity or solubilising preservative agent such as Germall 115, the methyl of hydroxy benzoic acid, ethyl, propyl group and butyl ester, benzylalcohol, EDTA, Euxyl (RTM) K400, Bromopol (2-bromo-2-nitro-1, ammediol) and benzene oxygen propanol; Antibacterial such as Irgasan (RTM) and phenoxyethanol (preferred content 0.1% is to about 5%); Solvable and colloidal state solubility humidizer such as hylaronic acid and SANWET such as USA-A-4,076, Sanwet (RTM) IM-1000 that the Celanese Superabsorbent Materials company of describing in 663 by the Portsmith of Virginia, USA provides, IM-1500 and IM-2500; Vitamin is as vitamin A, C, E and K; α-and beta-hydroxy acid; Lu Yun; Sphingosine, phytosphingosine, cholesterol; Skin whitener; The N-acetylcysteine; Toner; Spice and spice solubilizing agent and additional surfactant/emulsifying agent such as alcohol ethoxylate, the ethyoxyl mulit-hydroxy fatty acid ester, wherein polyol can be from glycerol, propylene glycol, ethylene glycol, sorbitol, anhydro sorbitol, polypropylene glycol is chosen in the dextrose plus saccharose.Example comprises monohydroxy tristerin and octadecanol, and wherein every mol of alcohol is on average used the ethoxylated octadecanol and the PEG-6 caprylic/capric glyceride of the oxirane of 10-200 mole.

Here available also have sun-proof reagent.A variety of sun-proof reagent have been described: people's such as mandate on February 11st, 1992 Haffey U.S.P.No.5,087,445 in following article; People's such as December in 1991 mandate on the 17th Turner U.S.P.No.5,073,372; People's such as December in 1991 mandate on the 17th Turner U.S.P.No.5,073,371; People such as Segarin, chapter 8, after 189 pages, " cosmetic science and technology ".In compositions of the present invention in the available sun-proof reagent, preferably be selected from p-methoxycinnamic acid 2-Octyl Nitrite, N, N-dimethyl para-amino benzoic acid 2-Octyl Nitrite, para-amino benzoic acid, 2-Phenylbenzimidazole-5-sulphuric acid, octocrilene, oxybenzone, the high  ester of salicylic acid, ethylhexyl salicylate, 4,4 '-methoxyl group-t-butyl dibenzoyl methane, 4-isopropyl diphenyl formyl methane, 3-benzylidene Camphora, 3-(4-methylbenzene methylene) Camphora, titanium dioxide, zinc oxide, Silicon stone, ferrum oxide, Parsol MCX, Eusolex 6300, octocrilene, Parsol 1789 and their mixture.

Also have some other available sunscreen open in following patent: to authorize the U.S.P.No.4 of Sabatelli, 937,370 June 26 nineteen ninety; People's such as mandate on March 12nd, 1991 Sabatelli U.S.P.No.4,999,186.Wherein in disclosed sun-proof reagent individual molecule 2 different chromophores with different ultraviolet radiation absorption spectrums are arranged.One of them chromophore mainly absorbs in the UVB radiation scope, and another absorbs in the UVA radiation scope by force.Compare with common sun-proof reagent, these sun-proof reagent are more effective, and the uv absorption scope is wideer, are difficult for penetrating into skin and effectiveness longer duration.Particularly preferred sun-proof reagent is selected from 2, the 4-N of 4-dihydroxy benaophenonel, N-(2-ethylhexyl) methylamino benzoate, the 4-N that forms with 4-hydroxy benzophenone acyl methane, the 4-N of N-(2-ethylhexyl) methylamino benzoate, 2-hydroxyl-4-(2-hydroxyl-oxethyl) benzophenone, the 4-N of N-(2-ethylhexyl) methylamino benzoate, 4-(2-hydroxyl-oxethyl) dibenzoyl methane, N-(2-ethylhexyl) methylamino benzoate, and their mixture.

Usually, sunscreen can account for about 0.5% to about 20% of compositions used herein.Its accurate consumption changes with selecteed sunscreen and desired sun protection factor (SPF).SPF is generally used for weighing sunscreen and prevents that illumination from playing erythema.See Federal Register, the 43rd volume, No.166, pp.38206-38269, on August 25th, 1978.

Compositions example of the present invention also comprises about by weight 0.1% to about 5% starch ocentyl succinic aluminum.Starch ocentyl succinic aluminum is the aluminum salt of the product of octenyl succinic acid anhydride and starch, and commercial trade name is from Dry Flo National Starch ﹠amp; Chemical Ltd..In this angle from dermal sensation and application characteristic, Dry Flo is useful.

Comprise pigment at these other optional raw material, if its non-dissolubility then be included in the total amount of oil phase composition.The pigment that is suitable for present composition use can be Organic substance and/or inorganic matter.Having the material of low color or low gloss such as unglazed lacquer and light scattering agent is also included within the pigment item.The example of suitable pigment has ferrum oxide, acyl glutamic acid iron oxides (acyglutamateiron oxide), ultramarine blue, D; The C dyestuff, carmine and composition thereof.Depend on types of compositions, use the mixture of pigment usually.From humidification, dermal sensation considers that from the angle of the skin appearance and the emulsion compatibility the preferred pigment that uses is treated pigment in addition.Pigment may be used chemical compound such as aminoacid, siloxanes, and lecithin and ester oil are handled.

Compositions pH value preferably about 4 is to about 9, and more preferably from about 6 to about 8.0.

The remainder of compositions is water or is suitable for aqueous carrier to topical application.Be about 30% to about 98.89%, preferred about 50% by weight to about 95% at the water content of this compositions, especially preferred about 60% to about 90%.

Preferably from the form of humidification breast or humidifying liquid, it is the retention type product that is applied to skin to the present composition.

Following examples are used to illustrate the present invention

Example I is to V

	I/％	II/％	III/％	IV/％	V/％
	I/％	II/％	III/％	IV/％	V/％	Spermol	0.72	0.5	0.8	0.65	0.75
Stearic acid	0.11	0.2	0.1	0.2	0.1	Spermol	0.72	0.5	0.8	0.65	0.75
Stearic acid	0.11	0.2	0.1	0.2	0.1	Steareth?100	0.1	0.1	0.15	0.15	0.15
Propyl p-hydroxybenzoate	0.17	0.08	0.07	0.15	0.07	Steareth?100	0.1	0.1	0.15	0.15	0.15
Propyl p-hydroxybenzoate	0.17	0.08	0.07	0.15	0.07	Arlatone(RTM)2121(1)	1.0	2.0	1.5	1.0	4.0
Glycerol	3	4	8	2.5	3.5	Arlatone(RTM)2121(1)	1.0	2.0	1.5	1.0	4.0
Glycerol	3	4	8	2.5	3.5	Carbopol(RTM)1382	0.1	0.075	0.08	0.075	0.075
Carbopol(RTM)954	0.7	0.56	0.5	0.65	0.45	Carbopol(RTM)1382	0.1	0.075	0.08	0.075	0.075
Carbopol(RTM)954	0.7	0.56	0.5	0.65	0.45	EDTA four sodium	0.1	0.2	0.1	0.1	0.1
Methyl parahydroxybenzoate	0.2	0.2	0.175	0.175	0.175	EDTA four sodium	0.1	0.2	0.1	0.1	0.1
Methyl parahydroxybenzoate	0.2	0.2	0.175	0.175	0.175	NaOH (40% solution)	1.0	0.8	0.8	0.8	0.8
Dimethicone Q21403	1.0	1.0	0.5	2.0	1.0	NaOH (40% solution)	1.0	0.8	0.8	0.8	0.8
Dimethicone Q21403	1.0	1.0	0.5	2.0	1.0	TiO ₂	0.15	0.15	0.15	0.15	0.15
Spice	0.2	0.2	-	0.2	-	TiO ₂	0.15	0.15	0.15	0.15	0.15
Spice	0.2	0.2	-	0.2	-	Urea	2.5	1.5	3	2	2.5
SEFA(2)	0.0	0.0	2.5	2.0	2.2	Urea	2.5	1.5	3	2	2.5
SEFA(2)	0.0	0.0	2.5	2.0	2.2	Benzoic acid octyl group dodecylate	0.0	0.0	0.0	1.0	1.0
KSG-18(3)	3.0	0.0	2.0	0.0	0.0	Benzoic acid octyl group dodecylate	0.0	0.0	0.0	1.0	1.0
KSG-18(3)	3.0	0.0	2.0	0.0	0.0	Silicon dioxide (4)	1.5	1.5	2.0	3.0	0.0
Polyethylene beads (5)	0.0	1.5	2.0	0.0	3.0	Silicon dioxide (4)	1.5	1.5	2.0	3.0	0.0
Polyethylene beads (5)	0.0	1.5	2.0	0.0	3.0	Colorant	0.0004	0.0002	0.0003	0.0	0.0
Water	To 100	To 100	To 100	To 100	To 100	Colorant	0.0004	0.0002	0.0003	0.0	0.0

1. provide by ICI.

2. liquid sucrose polyfatty acid esters, it is the mixture of six esters, seven esters and octaester with the sucrose of blended soy(a)-bean oil fatty acid esterification, mainly is octaester.

3. provide by Shinetsu chemistry company limited.

4. the Silica Bead SB-300 that provides by Miyoshi Kasei Inc..

5. the Flo-Beads LE-1080 that provides by Sumitomoo Seika chemistry company limited.

Preparation of compositions is as follows:

Thickening agent, presumable silicon dioxide, methyl parahydroxybenzoate, glycerol/TiO ₂Pre-composition, Arlatone 2121 and other water-soluble components except urea mix in water and be heated to 80 ℃ makes first kind of premix material.By mixing and adding second oil phase of hot preparation and become 0 part of premix material and be added in the water premix material except silicone gum.

The gained mixture is cooled to 60 ℃, then NaOH solution, EDTA, presumable polyethylene, presumable KSG-18, silicone gum and urea solution then (molten 1g in the 1ml water) are added in the O/w emulsion of making cooling mixture before adding accessory constituent.Compositions is prepared packing.

The improved humidification of compositions display, dermal sensation and skin protection characteristic and minimizing oiliness and excellent rubbing are wiped and are infiltrated and fast absorption characteristic.

Claims

1. the skin care compositions of an O/w emulsion form, it comprises:

(a) from 0.1% to 10% heavy comprises poly particulate component, and its mean diameter is 50 μ m or lower;

(b) from 0.1% to the 20% organic amphiphilic surfactant that can form liquid crystal that weighs;

(c) emulsive oil phase; With

(d) water.

2. according to the compositions of claim 1, wherein the mean diameter of particulate component is 30 microns or lower.

3. according to the compositions of claim 1 or 2, wherein the mean diameter of particulate component is 20 microns or lower.

4. according to the compositions of claim 3, wherein the mean diameter of particulate component is 2 microns to 8 microns.

5. according to each compositions of claim 1 to 4, wherein particulate component is selected from inert inorganic metal-oxide, silicon derivatized particles thing and polyethylene and composition thereof.

6. according to each compositions of claim 1 to 5, wherein particulate component also comprises inert inorganic metal-oxide, silicon derivatized particles thing or its mixture.

7. according to each compositions of claim 1 to 6, wherein said particulate component also comprises silicon dioxide.

8. according to each compositions of claim 1 to 7, wherein amphiphilic surfactant is selected from polyol ester, alkoxylated polyol ester and composition thereof.

9. compositions according to Claim 8, wherein said ester is selected from list, two and three esters.

10. according to each compositions of claim 1 to 9, wherein surfactant is the blend of stearic acid Isosorbide Dinitrate and theobromic acid sucrose ester.

11. according to each compositions of claim 1 to 10, also comprise the oil phase component that accounts for composition weight 1% to 60% in addition, this oil phase component comprises the liquid polyol carboxylate that accounts for composition weight 0.01% to 20%, this ester has polyol moiety and at least 4 carboxylic moiety, wherein polyol moiety is selected from sugar and the sugar alcohol that contains 4 to 8 hydroxyls, and wherein each carboxylic moiety has 8 to 22 carbon atoms, and wherein said liquid polyol carboxylate has the complete fusing point less than 30 ℃.

12. according to the compositions of claim 11, wherein said liquid polyol carboxylate contains and is no more than 2 free hydroxyl.

13. according to the compositions of claim 11 or 12, wherein said carboxylic moiety contains 14 to 18 carbon atoms.

14. according to each compositions of claim 11 to 13, wherein said polyol moiety is selected from erithritol, xylitol, sorbitol, glucose, sucrose and composition thereof.

15. according to each compositions of claim 11 to 13, wherein said polyol moiety is a sucrose.

16. according to each compositions of claim 11 to 14, the complete fusing point of wherein said liquid polyol carboxylate is lower than 27.5 ℃.

17. according to each compositions of claim 11 to 15, the complete fusing point of wherein said liquid polyol carboxylic acid polyester is lower than 25 ℃.

18. according to each compositions of claim 11 to 16, wherein said liquid polyol carboxylate is selected from sucrose five oleates, sucrose six oleates, sucrose seven oleates, sucrose eight oleates and composition thereof.

19. according to each compositions of claim 1 to 18, comprise the phase that contains polysiloxanes, this comprises crosslinked poly-organopolysiloxane and silicone oil mutually, wherein compositions comprises 0.1% to the 20% heavy crosslinked poly-organopolysiloxane and the mixture of silicone oil.

20., comprise and account for the crosslinked poly-organopolysiloxane of composition weight 0.5% to 10% and the mixture of silicone oil according to each compositions of claim 1 to 19.

21., comprise the crosslinked poly-organopolysiloxane that accounts for composition weight about 0.5% to about 5% and the mixture of silicone oil according to the compositions of claim 20.

22. according to Claim 8 or 21 compositions, the wherein crosslinked poly-organopolysiloxane and the mixture of silicone oil are made up of 10% to 40% crosslinked polymer that accounts for its weight and 60% to 90% the silicone oil that accounts for its weight.

23. according to the compositions of claim 22, the wherein crosslinked poly-organopolysiloxane and the mixture of silicone oil are made up of 20% to 30% crosslinked polymer that accounts for its weight and 70% to 80% the silicone oil that accounts for its weight.

24. according to each compositions of claim 19 to 23, wherein crosslinked poly-organopolysiloxane comprises and is crosslinked the crosslinked poly-organopolysiloxane of agent, wherein cross-linking agent has the following formula structure:

Wherein R1 is methyl, ethyl, propyl group or phenyl, R2 be H or-(CH ₂) nCH=CH ₂, z is 1 to 1000 number.

25. according to the compositions of claim 24, wherein cross-linking agent has the following formula structure:

Wherein x is 1 to 1000.

26. according to the compositions of claim 24 or 25, wherein crosslinked polysiloxane comprises the cross-linking agent that accounts for its weight 10% to 50%.

27. according to the compositions of claim 26, wherein crosslinked polysiloxane comprises the cross-linking agent that accounts for its weight 20% to 30%.

28. according to each compositions of claim 24 to 27, wherein poly-organopolysiloxane is selected from the polymer of following formula

Wherein R1 is methyl, ethyl, propyl group or phenyl, R2 be H or-(CH ₂) nCH=CH ₂, R3 and R4 independently are selected from methyl, ethyl, propyl group and phenyl, and p is 1 to 2000 integer, and q is 1 to 1000 integer.

29. according to each compositions of claim 24 to 28, wherein poly-organopolysiloxane is selected from the polymer of following formula:

Wherein l is 1 to 1000 integer, and m is 0 to 1000 integer, and n is 1 to 1000 integer.

30. according to the compositions of claim 29, wherein m is 1 to 1000 integer.

31. according to the compositions of claim 30, wherein m is 200 to about 800 integer.

32. according to each compositions of claim 24 to 31, wherein silicone oil is selected from weight average molecular weight about 100,000 or lower silicone oil.

33. according to the compositions of claim 32, wherein silicone oil is selected from weight average molecular weight 50,000 or lower silicone oil.

34. according to the compositions of claim 33, wherein silicone oil is selected from the silicone oil of weight average molecular weight 100 to 50,000.

35. according to the compositions of claim 34, wherein silicone oil is selected from the silicone oil of weight average molecular weight 200 to 40,000.

36. according to each compositions of claim 24 to 35, wherein silicone oil is selected from dimethicone, decamethylcyclopentaandoxane, octamethylcy-clotetrasiloxane and phenyl methyl polysiloxanes and composition thereof.

37. according to each compositions of claim 24 to 36, wherein silicone oil is the phenyl methyl polysiloxanes.

38. according to each compositions of claim 1 to 37, wherein particulate matter is selected from silicon dioxide and poly mixture, weight ratio is 3: 1 to 1: 3.

39. according to the compositions of claim 38, wherein particulate matter is selected from silicon dioxide and poly mixture, weight ratio is 2: 1 to 1: 2.

40., comprise 0.1% to 20% heavy urea in addition according to each compositions of claim 1 to 39.

41., comprise 0.5% to 10% heavy urea in addition according to the compositions of claim 40.

42., comprise 1% to 5% heavy urea in addition according to each compositions of claim 1 to 39.

43. according to each compositions of claim 1 to 42, comprise 0.1% to 20% heavy wetting agent in addition, be selected from glycerol, polymethyl acid glyceride lubricant, butanediol, sorbitol, pantothenylol, propylene glycol, hexanediol, ethoxylated glucose derivant, hexanetriol and glucose ether and composition thereof.

44. according to the compositions of claim 43, wherein wetting agent is a glycerol.

45. a retention type humidification emulsion comprises:

(a) from 0.1% to 10% heavy comprises poly particulate material, and its mean diameter is 50 μ m or lower;

(b) emulsive oil phase; With

(c) water.

46. the cosmetic method of nursing skin comprises to each skin care compositions of dermal administration claim 1 to 45.